Kathrin Plath - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
X Chromosome inactivation
Website:
http://www.biolchem.ucla.edu/labs/plath/

136 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Allison T, Langerman J, Sabri S, Otero-Garcia M, Lund A, Huang J, Wei X, Samarasinghe RA, Polioudakis D, Mody I, Cobos I, Novitch BG, Geschwind DH, Plath K, Lowry WE. Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis. Stem Cell Reports. PMID 34506726 DOI: 10.1016/j.stemcr.2021.08.006  1
2021 Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Fotion NN, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, et al. Identification of neural oscillations and epileptiform changes in human brain organoids. Nature Neuroscience. PMID 34426698 DOI: 10.1038/s41593-021-00906-5  1
2021 Deng W, Jacobson EC, Collier AJ, Plath K. The transcription factor code in iPSC reprogramming. Current Opinion in Genetics & Development. 70: 89-96. PMID 34246082 DOI: 10.1016/j.gde.2021.06.003  1
2021 Carraro G, Langerman J, Sabri S, Lorenzana Z, Purkayastha A, Zhang G, Konda B, Aros CJ, Calvert BA, Szymaniak A, Wilson E, Mulligan M, Bhatt P, Lu J, Vijayaraj P, ... ... Plath K, et al. Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition. Nature Medicine. PMID 33958799 DOI: 10.1038/s41591-021-01332-7  1
2021 Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, et al. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition. Nature Communications. 12: 1876. PMID 33767183 DOI: 10.1038/s41467-021-22166-4  1
2021 Deng W, Sha J, Plath K, Wohlschlegel JA. CMMB (Carboxylate Modified Magnetic Bead) -based isopropanol gradient peptide fractionation (CIF) enables rapid and robust off-line peptide mixture fractionation in bottom-up proteomics. Molecular & Cellular Proteomics : McP. 100039. PMID 33476790 DOI: 10.1074/mcp.RA120.002411  1
2021 Guo J, Sosa E, Chitiashvili T, Nie X, Rojas EJ, Oliver E, Plath K, Hotaling JM, Stukenborg JB, Clark AT, Cairns BR. Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment. Cell Stem Cell. PMID 33453151 DOI: 10.1016/j.stem.2020.12.004  1
2020 Patananan AN, Sercel AJ, Wu TH, Ahsan FM, Torres A, Kennedy SAL, Vandiver A, Collier AJ, Mehrabi A, Van Lew J, Zakin L, Rodriguez N, Sixto M, Tadros W, Lazar A, ... ... Plath K, et al. Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates. Cell Reports. 33: 108562. PMID 33378680 DOI: 10.1016/j.celrep.2020.108562  1
2020 Meshorer E, Plath K. Chromatin and Nuclear Architecture in Stem Cells. Stem Cell Reports. 15: 1155-1157. PMID 33296671 DOI: 10.1016/j.stemcr.2020.11.012  1
2020 Purkayastha A, Sen C, Garcia G, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, ... ... Plath K, et al. Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response. Cell Stem Cell. PMID 33259798 DOI: 10.1016/j.stem.2020.11.010  1
2020 Chitiashvili T, Dror I, Kim R, Hsu FM, Chaudhari R, Pandolfi E, Chen D, Liebscher S, Schenke-Layland K, Plath K, Clark A. Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation. Nature Cell Biology. PMID 33257808 DOI: 10.1038/s41556-020-00607-4  1
2020 Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Leon WRM, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, ... ... Plath K, et al. Publisher Correction: A protein assembly mediates Xist localization and gene silencing. Nature. PMID 33005055 DOI: 10.1038/s41586-020-2790-y  1
2020 Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Mancia Leon WR, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, ... ... Plath K, et al. A protein assembly mediates Xist localization and gene silencing. Nature. PMID 32908311 DOI: 10.1038/S41586-020-2703-0  1
2020 Purkayastha A, Sen C, Garcia G, Langerman J, Vijayaraj P, Shia DW, Meneses LK, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response. Biorxiv : the Preprint Server For Biology. PMID 32766588 DOI: 10.1101/2020.07.28.226092  1
2020 Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, ... Plath K, et al. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. 27: 181-185. PMID 32619514 DOI: 10.1016/j.stem.2020.06.006  1
2020 Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, ... Plath K, et al. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. PMID 32396864 DOI: 10.1016/J.Stem.2020.04.017  1
2019 Takahashi R, Grzenda A, Allison T, Rawnsley J, Balin SJ, Sabri S, Plath K, Lowry WE. Defining transcriptional signatures of human hair follicle cell states. The Journal of Investigative Dermatology. PMID 31676413 DOI: 10.1016/J.Jid.2019.07.726  1
2019 Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, ... ... Plath K, et al. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. PMID 31303374 DOI: 10.1016/J.Neuron.2019.06.011  1
2019 Bonora G, Rubbi L, Morselli M, Ma F, Chronis C, Plath K, Pellegrini M. DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS). Plos One. 14: e0214368. PMID 30946758 DOI: 10.1371/Journal.Pone.0214368  1
2019 Zhang W, Chronis C, Chen X, Zhang H, Spalinskas R, Pardo M, Chen L, Wu G, Zhu Z, Yu Y, Yu L, Choudhary J, Nichols J, Parast MM, Greber B, ... ... Plath K, et al. The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation. Cell Stem Cell. 24: 138-152.e8. PMID 30609396 DOI: 10.1016/J.Stem.2018.12.001  1
2018 Fu K, Chronis C, Soufi A, Bonora G, Edwards M, Smale ST, Zaret KS, Plath K, Pellegrini M. Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming. Bmc Genomics. 19: 956. PMID 30577748 DOI: 10.1186/S12864-018-5326-1  1
2018 Sun F, Chronis C, Kronenberg M, Chen XF, Su T, Lay FD, Plath K, Kurdistani SK, Carey MF. Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods. Molecular Cell. PMID 30527662 DOI: 10.1016/J.Molcel.2018.10.039  1
2018 Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, ... Plath K, et al. Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature Methods. PMID 30127506 DOI: 10.1038/S41592-018-0104-1  1
2018 Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA. Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. Journal of Visualized Experiments : Jove. PMID 29985359 DOI: 10.3791/57760  1
2018 Sahakyan A, Yang Y, Plath K. The Role of Xist in X-Chromosome Dosage Compensation. Trends in Cell Biology. PMID 29910081 DOI: 10.1016/J.Tcb.2018.05.005  1
2018 Allison TF, Smith AJH, Anastassiadis K, Sloane-Stanley J, Biga V, Stavish D, Hackland J, Sabri S, Langerman J, Jones M, Plath K, Coca D, Barbaric I, Gokhale P, Andrews PW. Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells. Stem Cell Reports. PMID 29779895 DOI: 10.1016/J.Stemcr.2018.04.015  1
2018 Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, ... ... Plath K, et al. Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. Stem Cell Reports. 10: 1453-1463. PMID 29742391 DOI: 10.1016/J.Stemcr.2018.04.001  1
2018 Pasque V, Karnik R, Chronis C, Petrella P, Langerman J, Bonora G, Song J, Vanheer L, Sadhu Dimashkie A, Meissner A, Plath K. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports. PMID 29681539 DOI: 10.1016/J.Stemcr.2018.03.019  1
2018 Keegan A, Plath K, Damoiseaux R. High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome. Methods in Molecular Biology (Clifton, N.J.). 1755: 75-87. PMID 29671264 DOI: 10.1007/978-1-4939-7724-6_6  1
2018 Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A. Correction: Epigenetic resetting of human pluripotency (doi:10.1242/dev.146811). Development (Cambridge, England). 145. PMID 29669738 DOI: 10.1242/Dev.166397  1
2018 Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, et al. Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nature Communications. 9: 754. PMID 29467410 DOI: 10.1038/S41467-018-02891-Z  1
2017 Sahakyan A, Plath K, Rougeulle C. Regulation of X-chromosome dosage compensation in human: mechanisms and model systems. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28947660 DOI: 10.1098/Rstb.2016.0363  1
2017 Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A. Epigenetic resetting of human pluripotency. Development (Cambridge, England). 144: 2748-2763. PMID 28765214 DOI: 10.1242/Dev.146811  1
2017 Huang C, Su T, Xue Y, Cheng C, Lay FD, McKee RA, Li M, Vashisht A, Wohlschlegel J, Novitch BG, Plath K, Kurdistani SK, Carey M. Cbx3 maintains lineage specificity during neural differentiation. Genes & Development. 31: 241-246. PMID 28270516 DOI: 10.1101/Gad.292169.116  1
2017 Chronis C, Fiziev P, Papp B, Butz S, Bonora G, Sabri S, Ernst J, Plath K. Cooperative Binding of Transcription Factors Orchestrates Reprogramming. Cell. PMID 28111071 DOI: 10.1016/J.Cell.2016.12.016  1
2016 Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K. Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell Stem Cell. PMID 27989770 DOI: 10.1016/J.Stem.2016.10.006  1
2016 Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJ, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Reports. PMID 27989715 DOI: 10.1016/J.Celrep.2016.11.054  1
2016 Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell. PMID 27618217 DOI: 10.1016/J.Stem.2016.08.008  1
2016 Sahakyan A, Plath K. Transcriptome Encyclopedia of Early Human Development. Cell. 165: 777-9. PMID 27153491 DOI: 10.1016/J.Cell.2016.04.042  1
2016 Pandya-Jones A, Plath K. The "lnc" between 3D Chromatin Structure and X Chromosome Inactivation. Seminars in Cell & Developmental Biology. PMID 27062886 DOI: 10.1016/J.Semcdb.2016.04.002  1
2016 Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT. Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell Stem Cell. 18: 323-329. PMID 26853856 DOI: 10.1016/J.Stem.2016.01.019  1
2015 Pasque V, Plath K. X chromosome reactivation in reprogramming and in development. Current Opinion in Cell Biology. 37: 75-83. PMID 26540406 DOI: 10.1016/J.Ceb.2015.10.006  1
2015 Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K. A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase. Epigenetics & Chromatin. 8: 42. PMID 26468331 DOI: 10.1186/S13072-015-0034-4  1
2015 McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, ... Plath K, et al. The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature. 521: 232-6. PMID 25915022 DOI: 10.1038/Nature14443  1
2014 Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, ... Plath K, et al. X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell. 159: 1681-97. PMID 25525883 DOI: 10.1016/J.Cell.2014.11.040  1
2014 Faingold CL, Kommajosyula SP, Long X, Plath K, Randall M. Serotonin and sudden death: differential effects of serotonergic drugs on seizure-induced respiratory arrest in DBA/1 mice. Epilepsy & Behavior : E&B. 37: 198-203. PMID 25064738 DOI: 10.1016/J.Yebeh.2014.06.028  1
2014 Minkovsky A, Sahakyan A, Rankin-Gee E, Bonora G, Patel S, Plath K. The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. Epigenetics & Chromatin. 7: 12. PMID 25028596 DOI: 10.1186/1756-8935-7-12  1
2014 Bonora G, Plath K, Denholtz M. A mechanistic link between gene regulation and genome architecture in mammalian development. Current Opinion in Genetics & Development. 27: 92-101. PMID 24998386 DOI: 10.1016/J.Gde.2014.05.002  1
2014 Valley NA, Blower PG, Wood SR, Plath KL, McWilliams LE, Richmond GL. Doubling down: delving into the details of diacid adsorption at aqueous surfaces. The Journal of Physical Chemistry. A. 118: 4778-89. PMID 24905587 DOI: 10.1021/Jp501498H  1
2013 Plath KL, Valley NA, Richmond GL. Ion-induced reorientation and distribution of pentanone in the air-water boundary layer. The Journal of Physical Chemistry. A. 117: 11514-27. PMID 24171463 DOI: 10.1021/Jp408188X  1
2013 Denholtz M, Bonora G, Chronis C, Splinter E, de Laat W, Ernst J, Pellegrini M, Plath K. Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell. 13: 602-16. PMID 24035354 DOI: 10.1016/J.Stem.2013.08.013  1
2013 Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA. Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1101-13. PMID 23949383 DOI: 10.4161/Epi.26025  1
2013 Trounson A, Daley GQ, Pasque V, Plath K. A new route to human embryonic stem cells. Nature Medicine. 19: 820-1. PMID 23836223 DOI: 10.1038/Nm.3266  1
2013 Engreitz JM, Pandya-Jones A, McDonel P, Shishkin A, Sirokman K, Surka C, Kadri S, Xing J, Goren A, Lander ES, Plath K, Guttman M. The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science (New York, N.Y.). 341: 1237973. PMID 23828888 DOI: 10.1126/Science.1237973  1
2013 Ho R, Papp B, Hoffman JA, Merrill BJ, Plath K. Stage-specific regulation of reprogramming to induced pluripotent stem cells by Wnt signaling and T cell factor proteins. Cell Reports. 3: 2113-26. PMID 23791530 DOI: 10.1016/J.Celrep.2013.05.015  1
2013 Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nature Cell Biology. 15: 872-82. PMID 23748610 DOI: 10.1038/Ncb2768  1
2013 Minkovsky A, Barakat TS, Sellami N, Chin MH, Gunhanlar N, Gribnau J, Plath K. The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo. Cell Reports. 3: 905-18. PMID 23523354 DOI: 10.1016/J.Celrep.2013.02.018  1
2013 Papp B, Plath K. Epigenetics of reprogramming to induced pluripotency. Cell. 152: 1324-43. PMID 23498940 DOI: 10.1016/J.Cell.2013.02.043  1
2012 Denholtz M, Plath K. Pluripotency in 3D: genome organization in pluripotent cells. Current Opinion in Cell Biology. 24: 793-801. PMID 23199754 DOI: 10.1016/J.Ceb.2012.11.001  1
2012 Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Translational Medicine. 1: 36-43. PMID 23197638 DOI: 10.5966/Sctm.2011-0001  1
2012 Chen XF, Lehmann L, Lin JJ, Vashisht A, Schmidt R, Ferrari R, Huang C, McKee R, Mosley A, Plath K, Kurdistani SK, Wohlschlegel J, Carey M. Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function. Cell Reports. 2: 1061-7. PMID 23177621 DOI: 10.1016/J.Celrep.2012.10.019  1
2012 Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR. Stem cells in the land of the rising sun: ISSCR 2012. Cell Stem Cell. 11: 607-14. PMID 23122288 DOI: 10.1016/J.Stem.2012.10.003  1
2012 Schmidt R, Plath K. The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation. Genome Biology. 13: 251. PMID 23088445 DOI: 10.1186/Gb-2012-13-10-251  1
2012 Pera MF, Plath K. Cell reprogramming. Current Opinion in Genetics & Development. 22: 401-2. PMID 23084811 DOI: 10.1016/J.Gde.2012.10.001  1
2012 Papp B, Plath K. Pluripotency re-centered around Esrrb. The Embo Journal. 31: 4255-7. PMID 23064149 DOI: 10.1038/Emboj.2012.285  1
2012 Nsair A, Schenke-Layland K, Van Handel B, Evseenko D, Kahn M, Zhao P, Mendelis J, Heydarkhan S, Awaji O, Vottler M, Geist S, Chyu J, Gago-Lopez N, Crooks GM, Plath K, et al. Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. Plos One. 7: e45603. PMID 23056209 DOI: 10.1371/Journal.Pone.0045603  1
2012 Diaz Perez SV, Kim R, Li Z, Marquez VE, Patel S, Plath K, Clark AT. Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin. Human Molecular Genetics. 21: 751-64. PMID 22058289 DOI: 10.1093/Hmg/Ddr506  1
2012 Minkovsky A, Patel S, Plath K. Concise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosome. Stem Cells (Dayton, Ohio). 30: 48-54. PMID 21997775 DOI: 10.1002/Stem.755  1
2011 Lin JJ, Lehmann LW, Bonora G, Sridharan R, Vashisht AA, Tran N, Plath K, Wohlschlegel JA, Carey M. Mediator coordinates PIC assembly with recruitment of CHD1. Genes & Development. 25: 2198-209. PMID 21979373 DOI: 10.1101/Gad.17554711  1
2011 Cooper AR, Patel S, Senadheera S, Plath K, Kohn DB, Hollis RP. Highly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration. Journal of Virological Methods. 177: 1-9. PMID 21784103 DOI: 10.1016/J.Jviromet.2011.06.019  1
2011 Sridharan R, Plath K. Small RNAs loom large during reprogramming. Cell Stem Cell. 8: 599-601. PMID 21624799 DOI: 10.1016/J.Stem.2011.05.009  1
2011 Plath K, Lowry WE. Progress in understanding reprogramming to the induced pluripotent state. Nature Reviews. Genetics. 12: 253-65. PMID 21415849 DOI: 10.1038/Nrg2955  1
2011 Papp B, Plath K. Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. Cell Research. 21: 486-501. PMID 21321600 DOI: 10.1038/Cr.2011.28  1
2011 Ho R, Chronis C, Plath K. Mechanistic insights into reprogramming to induced pluripotency. Journal of Cellular Physiology. 226: 868-78. PMID 20945378 DOI: 10.1002/Jcp.22450  1
2010 Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 7: 521-31. PMID 20887957 DOI: 10.1016/J.Stem.2010.07.017  1
2010 Mason MJ, Plath K, Zhou Q. Identification of context-dependent motifs by contrasting ChIP binding data. Bioinformatics (Oxford, England). 26: 2826-32. PMID 20870645 DOI: 10.1093/Bioinformatics/Btq546  1
2010 Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 7: 329-42. PMID 20727844 DOI: 10.1016/J.Stem.2010.06.024  1
2010 Chin MH, Pellegrini M, Plath K, Lowry WE. Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell. 7: 263-9. PMID 20682452 DOI: 10.1016/J.Stem.2010.06.019  1
2010 Takahashi K, Plath KL, Axson JL, Nelson GC, Skodje RT, Vaida V. Dynamics and spectroscopy of vibrational overtone excited glyoxylic acid and 2,2-dihydroxyacetic acid in the gas-phase. The Journal of Chemical Physics. 132: 094305. PMID 20210396 DOI: 10.1063/1.3327839  1
2010 Hiratani I, Ryba T, Itoh M, Rathjen J, Kulik M, Papp B, Fussner E, Bazett-Jones DP, Plath K, Dalton S, Rathjen PD, Gilbert DM. Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Research. 20: 155-69. PMID 19952138 DOI: 10.1101/Gr.099796.109  1
2010 Meshorer E, Plath K. Preface Advances in Experimental Medicine and Biology. 695: v-vii.  1
2009 Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST. Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes & Development. 23: 2824-38. PMID 20008934 DOI: 10.1101/Gad.1861209  1
2009 Mason MJ, Fan G, Plath K, Zhou Q, Horvath S. Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. Bmc Genomics. 10: 327. PMID 19619308 DOI: 10.1186/1471-2164-10-327  1
2009 Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 460: 863-8. PMID 19587682 DOI: 10.1038/Nature08212  1
2009 Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, ... ... Plath K, et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 5: 111-23. PMID 19570518 DOI: 10.1016/J.Stem.2009.06.008  1
2009 Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells (Dayton, Ohio). 27: 806-11. PMID 19350680 DOI: 10.1002/Stem.31  1
2009 Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells (Dayton, Ohio). 27: 783-95. PMID 19350678 DOI: 10.1002/Stem.13  1
2009 Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell. 4: 200-1; author reply . PMID 19265657 DOI: 10.1016/J.Stem.2009.02.009  1
2009 Plath KL, Takahashi K, Skodje RT, Vaida V. Fundamental and overtone vibrational spectra of gas-phase pyruvic acid. The Journal of Physical Chemistry. A. 113: 7294-303. PMID 19260671 DOI: 10.1021/Jp810687T  1
2009 Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. 33: 417-27. PMID 19250903 DOI: 10.1016/J.Molcel.2009.02.004  1
2009 Saxe JP, Tomilin A, Schöler HR, Plath K, Huang J. Post-translational regulation of Oct4 transcriptional activity. Plos One. 4: e4467. PMID 19221599 DOI: 10.1371/Journal.Pone.0004467  1
2009 Hochedlinger K, Plath K. Epigenetic reprogramming and induced pluripotency. Development (Cambridge, England). 136: 509-23. PMID 19168672 DOI: 10.1242/Dev.020867  1
2009 Sridharan R, Tchieu J, Mason MJ, Yachechko R, Kuoy E, Horvath S, Zhou Q, Plath K. Role of the murine reprogramming factors in the induction of pluripotency. Cell. 136: 364-77. PMID 19167336 DOI: 10.1016/J.Cell.2009.01.001  1
2009 Kanellopoulou C, Muljo SA, Dimitrov SD, Chen X, Colin C, Plath K, Livingston DM. X chromosome inactivation in the absence of Dicer. Proceedings of the National Academy of Sciences of the United States of America. 106: 1122-7. PMID 19164542 DOI: 10.1073/Pnas.0812210106  1
2009 Plath KL, Axson JL, Nelson GC, Takahashi K, Skodje RT, Vaidaa V. Gas-phase vibrational spectra of glyoxylic acid and its gem diol monohydrate. Implications for atmospheric chemistry Reaction Kinetics and Catalysis Letters. 96: 209-224. DOI: 10.1007/S11144-009-5528-2  1
2008 Lowry WE, Plath K. The many ways to make an iPS cell. Nature Biotechnology. 26: 1246-8. PMID 18997764 DOI: 10.1038/Nbt1108-1246  1
2008 Takahashi K, Plath KL, Skodje RT, Vaida V. Dynamics of vibrational overtone excited pyruvic acid in the gas phase: line broadening through hydrogen-atom chattering. The Journal of Physical Chemistry. A. 112: 7321-31. PMID 18637664 DOI: 10.1021/Jp803225C  1
2008 Schenke-Layland K, Rhodes KE, Angelis E, Butylkova Y, Heydarkhan-Hagvall S, Gekas C, Zhang R, Goldhaber JI, Mikkola HK, Plath K, MacLellan WR. Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells (Dayton, Ohio). 26: 1537-46. PMID 18450826 DOI: 10.1634/Stemcells.2008-0033  1
2008 Sridharan R, Plath K. Illuminating the black box of reprogramming. Cell Stem Cell. 2: 295-7. PMID 18397745 DOI: 10.1016/J.Stem.2008.03.015  1
2008 Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 105: 2883-8. PMID 18287077 DOI: 10.1073/Pnas.0711983105  1
2007 Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 1: 55-70. PMID 18371336 DOI: 10.1016/J.Stem.2007.05.014  1
2007 Nusinow DA, Sharp JA, Morris A, Salas S, Plath K, Panning B. The histone domain of macroH2A1 contains several dispersed elements that are each sufficient to direct enrichment on the inactive X chromosome. Journal of Molecular Biology. 371: 11-8. PMID 17570398 DOI: 10.1016/J.Jmb.2007.05.063  1
2007 Lane JR, Kjaergaard HG, Plath KL, Vaida V. Overtone spectroscopy of sulfonic acid derivatives. The Journal of Physical Chemistry. A. 111: 5434-40. PMID 17542563 DOI: 10.1021/Jp0688005  1
2007 Cushman-Vokoun AM, Plath KB, Landmark JD, Stickle DF. Predicted influence of sample hematocrit on injected mass of internal standard in mass spectrometry assays utilizing simple protein precipitation for sample preparation. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 45: 215-9. PMID 17311511 DOI: 10.1515/Cclm.2007.044  1
2006 Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/J.Cell.2006.02.041  1
2006 Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 441: 349-53. PMID 16625203 DOI: 10.1038/Nature04733  1
2006 Beard C, Hochedlinger K, Plath K, Wutz A, Jaenisch R. Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis (New York, N.Y. : 2000). 44: 23-8. PMID 16400644 DOI: 10.1002/Gene.20180  1
2006 Chu F, Nusinow DA, Chalkley RJ, Plath K, Panning B, Burlingame AL. Mapping post-translational modifications of the histone variant MacroH2A1 using tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 5: 194-203. PMID 16210244 DOI: 10.1074/Mcp.M500285-Mcp200  1
2005 de la Cruz CC, Fang J, Plath K, Worringer KA, Nusinow DA, Zhang Y, Panning B. Developmental regulation of Suz 12 localization. Chromosoma. 114: 183-92. PMID 15986205 DOI: 10.1007/S00412-005-0008-6  1
2004 Plath K, Talbot D, Hamer KM, Otte AP, Yang TP, Jaenisch R, Panning B. Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome. The Journal of Cell Biology. 167: 1025-35. PMID 15596546 DOI: 10.1083/Jcb.200409026  1
2004 Plath K, Wilkinson BM, Stirling CJ, Rapoport TA. Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum. Molecular Biology of the Cell. 15: 1-10. PMID 14617809 DOI: 10.1091/Mbc.E03-06-0390  1
2004 Ghadouani A, Pinel-Alloul B, Plath K, Codd GA, Lampert W. Effects of Microcystis aeruginosa and purified microcystin-LR on the feeding behavior of Daphnia pulicaria Limnology and Oceanography. 49: 666-679. DOI: 10.4319/Lo.2004.49.3.0666  1
2004 Kraetge A, Kalkner W, Plath KD, Plath R. Transiente Öldruckmessung zur Diagnose der Kurzschlussfestigkeit von Leistungstransformatoren Etg-Fachberichte (Energietechnische Gesellschaft Im Vde). 109-113.  1
2003 Plath K, Fang J, Mlynarczyk-Evans SK, Cao R, Worringer KA, Wang H, de la Cruz CC, Otte AP, Panning B, Zhang Y. Role of histone H3 lysine 27 methylation in X inactivation. Science (New York, N.Y.). 300: 131-5. PMID 12649488 DOI: 10.1126/Science.1084274  1
2003 Plath KE, Grabbe J, Gibbs BF. Calcineurin antagonists differentially affect mediator secretion, p38 mitogen-activated protein kinase and extracellular signal-regulated kinases from immunologically activated human basophils. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 33: 342-50. PMID 12614449 DOI: 10.1046/j.1365-2222.2003.01610.x  1
2002 Plath K, Mlynarczyk-Evans S, Nusinow DA, Panning B. Xist RNA and the mechanism of X chromosome inactivation. Annual Review of Genetics. 36: 233-78. PMID 12429693 DOI: 10.1146/Annurev.Genet.36.042902.092433  1
2002 Gibbs BF, Plath KE, Wolff HH, Grabbe J. Regulation of mediator secretion in human basophils by p38 mitogen-activated protein kinase: phosphorylation is sensitive to the effects of phosphatidylinositol 3-kinase inhibitors and calcium mobilization. Journal of Leukocyte Biology. 72: 391-400. PMID 12149431  1
2002 Plath KD, Plath R, Emanuel H, Kalkner W. Synchrone dreiphasige teilentladungsmessung an leistungstranformatoren vor ort und im labor Etg-Fachberichte (Energietechnische Gesellschaft Im Vde). 69-72.  1
2002 Plath KD, Plath R, Kalkner W. Diagnose der kurzschlussfestigkeit von leistungstransformatoren vor Ort Etg-Fachberichte (Energietechnische Gesellschaft Im Vde). 189-192.  1
2001 Strenzke N, Grabbe J, Plath KE, Rohwer J, Wolff HH, Gibbs BF. Mercuric chloride enhances immunoglobulin E-dependent mediator release from human basophils. Toxicology and Applied Pharmacology. 174: 257-63. PMID 11485386 DOI: 10.1006/taap.2001.9223  1
2001 Plath KE, Grabbe J, Strenzke N, Wolff HH, Gibbs BF. Effect of chloride channel blockers on anti-IgE-stimulated histamine and IL-4/IL-13 release from human basophils. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 50: S51-2. PMID 11411600  1
2001 Strenzke N, Grabbe J, Plath KE, Wolff HH, Gibbs BF. Effects of antioxidant vitamins on anti-IgE-induced mediator release from human basophils. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 50: S49-50. PMID 11411599  1
2001 Plath K, Boersma M. Mineral limitation of zooplankton: Stoichiometric constraints and optimal foraging Ecology. 82: 1260-1269.  1
2000 Menetret JF, Neuhof A, Morgan DG, Plath K, Radermacher M, Rapoport TA, Akey CW. The structure of ribosome-channel complexes engaged in protein translocation. Molecular Cell. 6: 1219-32. PMID 11106759 DOI: 10.1016/S1097-2765(00)00118-0  1
2000 Plath K, Rapoport TA. Spontaneous release of cytosolic proteins from posttranslational substrates before their transport into the endoplasmic reticulum. The Journal of Cell Biology. 151: 167-78. PMID 11018062 DOI: 10.1083/Jcb.151.1.167  1
1999 Rapoport TA, Matlack KE, Plath K, Misselwitz B, Staeck O. Posttranslational protein translocation across the membrane of the endoplasmic reticulum. Biological Chemistry. 380: 1143-50. PMID 10595576 DOI: 10.1515/Bc.1999.145  1
1999 Matlack KE, Misselwitz B, Plath K, Rapoport TA. BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane. Cell. 97: 553-64. PMID 10367885 DOI: 10.1016/S0092-8674(00)80767-9  1
1998 Plath K, Mothes W, Wilkinson BM, Stirling CJ, Rapoport TA. Signal sequence recognition in posttranslational protein transport across the yeast ER membrane. Cell. 94: 795-807. PMID 9753326 DOI: 10.1016/S0092-8674(00)81738-9  1
1998 Plath K. Adaptive feeding behavior of Daphnia magna in response to short-term starvation Limnology and Oceanography. 43: 593-599.  1
1997 Matlack KE, Plath K, Misselwitz B, Rapoport TA. Protein transport by purified yeast Sec complex and Kar2p without membranes. Science (New York, N.Y.). 277: 938-41. PMID 9252322 DOI: 10.1126/Science.277.5328.938  1
1996 Hanein D, Matlack KE, Jungnickel B, Plath K, Kalies KU, Miller KR, Rapoport TA, Akey CW. Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation. Cell. 87: 721-32. PMID 8929540 DOI: 10.1016/S0092-8674(00)81391-4  1
1996 Finke K, Plath K, Panzner S, Prehn S, Rapoport TA, Hartmann E, Sommer T. A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae. The Embo Journal. 15: 1482-94. PMID 8612571 DOI: 10.1002/J.1460-2075.1996.Tb00492.X  1
1995 Engel K, Schultz H, Martin F, Kotlyarov A, Plath K, Hahn M, Heinemann U, Gaestel M. Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif. The Journal of Biological Chemistry. 270: 27213-21. PMID 7592979 DOI: 10.1074/Jbc.270.45.27213  1
1994 Plath K, Engel K, Schwedersky G, Gaestel M. Characterization of the proline-rich region of mouse MAPKAP kinase 2: influence on catalytic properties and binding to the c-abl SH3 domain in vitro. Biochemical and Biophysical Research Communications. 203: 1188-94. PMID 8093038 DOI: 10.1006/Bbrc.1994.2308  1
1993 Engel K, Plath K, Gaestel M. The MAP kinase-activated protein kinase 2 contains a proline-rich SH3-binding domain. Febs Letters. 336: 143-7. PMID 8262198 DOI: 10.1016/0014-5793(93)81628-D  1
1914 Plath K. With the Tropic‐birds in Bermuda Ibis. 56: 552-559. DOI: 10.1111/j.1474-919X.1914.tb06645.x  1
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