Marius Wernig - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
iPS cells, Transdifferentiation
Website:
http://stemcell.stanford.edu/about/werniglab.html

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, Srinivasan R, Li X, Devarajan K, Prélot L, Ang CE, Shibuya Y, Benayoun BA, Chang ALS, Wernig M, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 574: 553-558. PMID 31645721 DOI: 10.1038/s41586-019-1658-5  0.64
2019 Huang YA, Zhou B, Nabet AM, Wernig M, Südhof TC. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31331998 DOI: 10.1523/JNEUROSCI.2994-18.2019  0.48
2019 Marro SG, Chanda S, Yang N, Janas JA, Valperga G, Trotter J, Zhou B, Merrill S, Yousif I, Shelby H, Vogel H, Kalani MYS, Südhof TC, Wernig M. Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons. Neuron. PMID 31257103 DOI: 10.1016/j.neuron.2019.05.043  0.48
2019 Chanda S, Ang CE, Lee QY, Ghebrial M, Haag D, Shibuya Y, Wernig M, Südhof TC. Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. Cell Stem Cell. PMID 31155484 DOI: 10.1016/j.stem.2019.04.021  0.64
2019 Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 8. PMID 30644360 DOI: 10.7554/eLife.40197  0.44
2019 Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, ... ... Wernig M, et al. The novel lncRNA is pro-neurogenic and mutated in human neurodevelopmental disorders. Elife. 8. PMID 30628890 DOI: 10.7554/eLife.41770  0.64
2018 Zhang Z, Marro SG, Zhang Y, Arendt KL, Patzke C, Zhou B, Fair T, Yang N, Südhof TC, Wernig M, Chen L. The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling. Science Translational Medicine. 10. PMID 30068571 DOI: 10.1126/scitranslmed.aar4338  0.48
2018 Ang CE, Wernig M. Profiling DNA-transcription factor interactions. Nature Biotechnology. 36: 501-502. PMID 29874211 DOI: 10.1038/nbt.4161  0.64
2018 Tanabe K, Ang CE, Chanda S, Olmos VH, Haag D, Levinson DF, Südhof TC, Wernig M. Transdifferentiation of human adult peripheral blood T cells into neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 29866841 DOI: 10.1073/pnas.1720273115  0.64
2017 Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, et al. Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons. Cell Reports. 20: 3236-3247. PMID 28954238 DOI: 10.1016/j.celrep.2017.09.011  0.64
2017 Chanda S, Hale WD, Zhang B, Wernig M, Südhof TC. Unique vs. Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28607166 DOI: 10.1523/JNEUROSCI.0125-17.2017  0.48
2017 Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, ... ... Wernig M, et al. Generation of pure GABAergic neurons by transcription factor programming. Nature Methods. PMID 28504679 DOI: 10.1038/nmeth.4291  0.64
2017 Mall M, Kareta MS, Chanda S, Ahlenius H, Perotti N, Zhou B, Grieder SD, Ge X, Drake S, Euong Ang C, Walker BM, Vierbuchen T, Fuentes DR, Brennecke P, Nitta KR, ... ... Wernig M, et al. Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates. Nature. PMID 28379941 DOI: 10.1038/nature21722  0.48
2017 Huang YA, Zhou B, Wernig M, Südhof TC. ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion. Cell. PMID 28111074 DOI: 10.1016/j.cell.2016.12.044  0.48
2016 Chao MP, Gentles AJ, Chatterjee S, Lan F, Reinisch A, Corces MR, Xavy S, Shen J, Haag D, Chanda S, Sinha R, Morganti RM, Nishimura T, Ameen M, Wu H, ... Wernig M, et al. Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease. Cell Stem Cell. PMID 28089908 DOI: 10.1016/j.stem.2016.11.018  0.48
2016 Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M. FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice. Proceedings of the National Academy of Sciences of the United States of America. 113: 8514-9. PMID 27402759 DOI: 10.1073/pnas.1607079113  0.48
2016 Treutlein B, Lee QY, Camp JG, Mall M, Koh W, Shariati SA, Sim S, Neff NF, Skotheim JM, Wernig M, Quake SR. Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq. Nature. PMID 27281220 DOI: 10.1038/nature18323  0.56
2016 Patzke C, Acuna C, Giam LR, Wernig M, Südhof TC. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. The Journal of Experimental Medicine. 213: 499-515. PMID 27001749 DOI: 10.1084/jem.20150951  0.48
2016 Carlson AL, Bennett NK, Francis NL, Halikere A, Clarke S, Moore JC, Hart RP, Paradiso K, Wernig M, Kohn J, Pang ZP, Moghe PV. Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds. Nature Communications. 7: 10862. PMID 26983594 DOI: 10.1038/ncomms10862  0.56
2016 Yi F, Danko T, Botelho SC, Patzke C, Pak C, Wernig M, Südhof TC. Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons. Science (New York, N.Y.). 352: aaf2669. PMID 26966193 DOI: 10.1126/science.aaf2669  0.48
2015 De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Corrigendum: Hallmarks of pluripotency. Nature. PMID 26675727 DOI: 10.1038/nature16470  0.56
2015 De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Wernig M, et al. Corrigendum: Failure to replicate the STAP cell phenomenon. Nature. PMID 26675720 DOI: 10.1038/nature16479  0.56
2015 Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, ... ... Wernig M, et al. The histone chaperone CAF-1 safeguards somatic cell identity. Nature. 528: 218-224. PMID 26659182 DOI: 10.1038/nature15749  0.56
2015 Kareta MS, Sage J, Wernig M. Crosstalk between stem cell and cell cycle machineries. Current Opinion in Cell Biology. 37: 68-74. PMID 26520682 DOI: 10.1016/j.ceb.2015.10.001  0.56
2015 Tanabe K, Haag D, Wernig M. Direct somatic lineage conversion. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26416679 DOI: 10.1098/rstb.2014.0368  0.56
2015 De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, ... ... Wernig M, et al. Failure to replicate the STAP cell phenomenon. Nature. 525: E6-9. PMID 26399835 DOI: 10.1038/nature15513  0.56
2015 De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Hallmarks of pluripotency. Nature. 525: 469-78. PMID 26399828 DOI: 10.1038/nature15515  0.56
2015 Patzke C, Han Y, Covy J, Yi F, Maxeiner S, Wernig M, Südhof TC. Analysis of conditional heterozygous STXBP1 mutations in human neurons. The Journal of Clinical Investigation. 125: 3560-71. PMID 26280581 DOI: 10.1172/JCI78612  0.48
2015 Pak C, Danko T, Zhang Y, Aoto J, Anderson G, Maxeiner S, Yi F, Wernig M, Südhof TC. Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1. Cell Stem Cell. 17: 316-28. PMID 26279266 DOI: 10.1016/j.stem.2015.07.017  0.48
2015 Lujan E, Zunder ER, Ng YH, Goronzy IN, Nolan GP, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 521: 352-6. PMID 25830878 DOI: 10.1038/nature14274  0.56
2015 Chanda S, Aoto J, Lee SJ, Wernig M, Südhof TC. Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking. Molecular Psychiatry. PMID 25778475 DOI: 10.1038/mp.2015.20  0.56
2015 Zunder ER, Lujan E, Goltsev Y, Wernig M, Nolan GP. A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. Cell Stem Cell. 16: 323-37. PMID 25748935 DOI: 10.1016/j.stem.2015.01.015  0.56
2015 Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O'Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, ... ... Wernig M, et al. Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis. Cell Stem Cell. 16: 39-50. PMID 25467916 DOI: 10.1016/j.stem.2014.10.019  0.56
2014 Batista PJ, Molinie B, Wang J, Qu K, Zhang J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, Carter AC, Flynn RA, Zhou C, Lim KS, Dedon P, ... Wernig M, et al. m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 15: 707-19. PMID 25456834 DOI: 10.1016/j.stem.2014.09.019  0.56
2014 Sebastiano V, Zhen HH, Haddad B, Derafshi BH, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, ... ... Wernig M, et al. Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. Science Translational Medicine. 6: 264ra163. PMID 25429056 DOI: 10.1126/scitranslmed.3009540  0.56
2014 Chanda S, Ang CE, Davila J, Pak C, Mall M, Lee QY, Ahlenius H, Jung SW, Südhof TC, Wernig M. Generation of induced neuronal cells by the single reprogramming factor ASCL1. Stem Cell Reports. 3: 282-96. PMID 25254342 DOI: 10.1016/j.stemcr.2014.05.020  0.64
2014 Ang CE, Wernig M. Induced neuronal reprogramming. The Journal of Comparative Neurology. 522: 2877-86. PMID 24771471 DOI: 10.1002/cne.23620  0.56
2014 Cho A, Tang Y, Davila J, Deng S, Chen L, Miller E, Wernig M, Graef IA. Calcineurin signaling regulates neural induction through antagonizing the BMP pathway. Neuron. 82: 109-24. PMID 24698271 DOI: 10.1016/j.neuron.2014.02.015  0.56
2014 Pak CH, Danko T, Zhang Y, Aoto J, Anderson G, Maxeiner S, Yi F, Wernig M, Südhof TC. Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused By Heterozygous Mutations in NRXN1 Cell Stem Cell. DOI: 10.1016/j.stem.2015.07.017  0.56
2013 Yang N, Wernig M. Harnessing the stem cell potential: a case for neural stem cell therapy. Nature Medicine. 19: 1580-1. PMID 24309657 DOI: 10.1038/nm.3425  0.56
2013 Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, ... ... Wernig M, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/j.cell.2013.09.028  0.48
2013 Chanda S, Marro S, Wernig M, Südhof TC. Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Proceedings of the National Academy of Sciences of the United States of America. 110: 16622-7. PMID 24046374 DOI: 10.1073/pnas.1316240110  0.48
2013 Webb AE, Pollina EA, Vierbuchen T, Urbán N, Ucar D, Leeman DS, Martynoga B, Sewak M, Rando TA, Guillemot F, Wernig M, Brunet A. FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. Cell Reports. 4: 477-91. PMID 23891001 DOI: 10.1016/j.celrep.2013.06.035  0.56
2013 Zhang Y, Pak C, Han Y, Ahlenius H, Zhang Z, Chanda S, Marro S, Patzke C, Acuna C, Covy J, Xu W, Yang N, Danko T, Chen L, Wernig M, et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron. 78: 785-98. PMID 23764284 DOI: 10.1016/j.neuron.2013.05.029  0.48
2013 Yang N, Zuchero JB, Ahlenius H, Marro S, Ng YH, Vierbuchen T, Hawkins JS, Geissler R, Barres BA, Wernig M. Generation of oligodendroglial cells by direct lineage conversion. Nature Biotechnology. 31: 434-9. PMID 23584610 DOI: 10.1038/nbt.2564  0.56
2013 Davila J, Chanda S, Ang CE, Südhof TC, Wernig M. Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts. Journal of Neuroscience Methods. 216: 104-9. PMID 23562599 DOI: 10.1016/j.jneumeth.2013.03.020  0.64
2013 Lujan E, Wernig M. An indirect approach to generating specific human cell types. Nature Methods. 10: 44-5. PMID 23269377 DOI: 10.1038/nmeth.2325  0.56
2012 Vierbuchen T, Wernig M. Molecular roadblocks for cellular reprogramming. Molecular Cell. 47: 827-38. PMID 23020854 DOI: 10.1016/j.molcel.2012.09.008  0.56
2012 Lujan E, Wernig M. The many roads to Rome: induction of neural precursor cells from fibroblasts. Current Opinion in Genetics & Development. 22: 517-22. PMID 22868177 DOI: 10.1016/j.gde.2012.07.002  0.56
2012 Lujan E, Chanda S, Ahlenius H, Südhof TC, Wernig M. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2527-32. PMID 22308465 DOI: 10.1073/pnas.1121003109  0.48
2011 Citri A, Pang ZP, Südhof TC, Wernig M, Malenka RC. Comprehensive qPCR profiling of gene expression in single neuronal cells. Nature Protocols. 7: 118-27. PMID 22193304 DOI: 10.1038/nprot.2011.430  0.48
2011 Yang N, Ng YH, Pang ZP, Südhof TC, Wernig M. Induced neuronal cells: how to make and define a neuron. Cell Stem Cell. 9: 517-25. PMID 22136927 DOI: 10.1016/j.stem.2011.11.015  0.48
2011 Ming GL, Brüstle O, Muotri A, Studer L, Wernig M, Christian KM. Cellular reprogramming: recent advances in modeling neurological diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16070-5. PMID 22072658 DOI: 10.1523/JNEUROSCI.4218-11.2011  0.56
2011 Vierbuchen T, Wernig M. Direct lineage conversions: unnatural but useful? Nature Biotechnology. 29: 892-907. PMID 21997635 DOI: 10.1038/nbt.1946  0.56
2011 Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell. 9: 374-82. PMID 21962918 DOI: 10.1016/j.stem.2011.09.002  0.48
2011 Sebastiano V, Maeder ML, Angstman JF, Haddad B, Khayter C, Yeo DT, Goodwin MJ, Hawkins JS, Ramirez CL, Batista LF, Artandi SE, Wernig M, Joung JK. In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells (Dayton, Ohio). 29: 1717-26. PMID 21898685 DOI: 10.1002/stem.718  0.56
2011 Pang ZP, Yang N, Vierbuchen T, Ostermeier A, Fuentes DR, Yang TQ, Citri A, Sebastiano V, Marro S, Südhof TC, Wernig M. Induction of human neuronal cells by defined transcription factors. Nature. 476: 220-3. PMID 21617644 DOI: 10.1038/nature10202  0.48
2011 Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, et al. Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature. 474: 399-402. PMID 21602826 DOI: 10.1038/nature10084  0.56
2010 Elefanty AG, Blelloch R, Passegué E, Wernig M, Mummery CL. On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell Stem Cell. 7: 443-50. PMID 20887950 DOI: 10.1016/j.stem.2010.09.002  0.56
2010 Lujan E, Wernig M. An imprinted signature helps isolate ESC-equivalent iPSCs. Cell Research. 20: 974-6. PMID 20697429 DOI: 10.1038/cr.2010.117  0.56
2010 Xi J, Khalil M, Shishechian N, Hannes T, Pfannkuche K, Liang H, Fatima A, Haustein M, Suhr F, Bloch W, Reppel M, Sarić T, Wernig M, Jänisch R, Brockmeier K, et al. Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2739-51. PMID 20371616 DOI: 10.1096/fj.09-145177  0.56
2010 Carette JE, Pruszak J, Varadarajan M, Blomen VA, Gokhale S, Camargo FD, Wernig M, Jaenisch R, Brummelkamp TR. Generation of iPSCs from cultured human malignant cells. Blood. 115: 4039-42. PMID 20233975 DOI: 10.1182/blood-2009-07-231845  0.56
2010 Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature. 463: 1035-41. PMID 20107439 DOI: 10.1038/nature08797  0.48
2009 Kuzmenkin A, Liang H, Xu G, Pfannkuche K, Eichhorn H, Fatima A, Luo H, Saric T, Wernig M, Jaenisch R, Hescheler J. Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4168-80. PMID 19703934 DOI: 10.1096/fj.08-128546  0.56
2009 Pfannkuche K, Liang H, Hannes T, Xi J, Fatima A, Nguemo F, Matzkies M, Wernig M, Jaenisch R, Pillekamp F, Halbach M, Schunkert H, Sarić T, Hescheler J, Reppel M. Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 24: 73-86. PMID 19590195 DOI: 10.1159/000227815  0.56
2008 Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 134: 521-33. PMID 18692474 DOI: 10.1016/j.cell.2008.07.020  0.56
2008 Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 454: 766-70. PMID 18600261 DOI: 10.1038/nature07107  0.56
2008 Wernig M, Lengner CJ, Hanna J, Lodato MA, Steine E, Foreman R, Staerk J, Markoulaki S, Jaenisch R. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nature Biotechnology. 26: 916-24. PMID 18594521 DOI: 10.1038/nbt1483  0.56
2008 Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis. Nature. 454: 49-55. PMID 18509334 DOI: 10.1038/nature07056  0.56
2008 Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell. 133: 250-64. PMID 18423197 DOI: 10.1016/j.cell.2008.03.028  0.56
2008 Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 5856-61. PMID 18391196 DOI: 10.1073/pnas.0801677105  0.56
2008 Brambrink T, Foreman R, Welstead GG, Lengner CJ, Wernig M, Suh H, Jaenisch R. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell. 2: 151-9. PMID 18371436 DOI: 10.1016/j.stem.2008.01.004  0.56
2008 Wernig M, Meissner A, Cassady JP, Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell. 2: 10-2. PMID 18371415 DOI: 10.1016/j.stem.2007.12.001  0.56
2008 Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A. Dissecting direct reprogramming through integrative genomic analysis (Nature (2008) 454, (49-55)) Nature. 454: 794. DOI: 10.1038/nature07196  0.56
2008 Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R. Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency (DOI:10.1016/j.cell.2008.03.028) Cell. 134: 365. DOI: 10.1016/j.cell.2008.07.013  0.56
2008 Wernig M, Lengner CJ, Hanna J. A drug-lnducible transgenic system for direct reprogramming of multiple somatic cell types Chemtracts. 21: 238-239.  0.56
2007 Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (New York, N.Y.). 318: 1920-3. PMID 18063756 DOI: 10.1126/science.1152092  0.56
2007 Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature Biotechnology. 25: 1177-81. PMID 17724450 DOI: 10.1038/nbt1335  0.56
2007 Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, ... ... Wernig M, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 448: 553-60. PMID 17603471 DOI: 10.1038/nature06008  0.56
2007 Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature. 448: 318-24. PMID 17554336 DOI: 10.1038/nature05944  0.56
2006 Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 125: 315-26. PMID 16630819 DOI: 10.1016/j.cell.2006.02.041  0.56
2006 Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 441: 349-53. PMID 16625203 DOI: 10.1038/nature04733  0.56
2005 Wernig G, Janzen V, Schäfer R, Zweyer M, Knauf U, Hoegemeier O, Mundegar RR, Garbe S, Stier S, Franz T, Wernig M, Wernig A. The vast majority of bone-marrow-derived cells integrated into mdx muscle fibers are silent despite long-term engraftment. Proceedings of the National Academy of Sciences of the United States of America. 102: 11852-7. PMID 16085712 DOI: 10.1073/pnas.0502507102  0.56
2004 Wernig M, Benninger F, Schmandt T, Rade M, Tucker KL, Büssow H, Beck H, Brüstle O. Functional integration of embryonic stem cell-derived neurons in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5258-68. PMID 15175396 DOI: 10.1523/JNEUROSCI.0428-04.200  0.56
2003 Benninger F, Beck H, Wernig M, Tucker KL, Brüstle O, Scheffler B. Functional integration of embryonic stem cell-derived neurons in hippocampal slice cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7075-83. PMID 12904468  0.56
2003 Steffel J, Wernig M, Knauf U, Kumar S, Wiestler OD, Wernig A, Brüstle O. Migration and differentiation of myogenic precursors following transplantation into the developing rat brain. Stem Cells (Dayton, Ohio). 21: 181-9. PMID 12634414 DOI: 10.1634/stemcells.21-2-181  0.56
2002 Wernig M, Tucker KL, Gornik V, Schneiders A, Buschwald R, Wiestler OD, Barde YA, Brüstle O. Tau EGFP embryonic stem cells: an efficient tool for neuronal lineage selection and transplantation. Journal of Neuroscience Research. 69: 918-24. PMID 12205684 DOI: 10.1002/jnr.10395  0.56
2002 Wernig M, Brüstle O. Fifty ways to make a neuron: shifts in stem cell hierarchy and their implications for neuropathology and CNS repair. Journal of Neuropathology and Experimental Neurology. 61: 101-10. PMID 11853015  0.56
2001 Zhang SC, Wernig M, Duncan ID, Brüstle O, Thomson JA. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nature Biotechnology. 19: 1129-33. PMID 11731781 DOI: 10.1038/nbt1201-1129  0.56
2000 Faiella A, Wernig M, Consalez GG, Hostick U, Hofmann C, Hustert E, Boncinelli E, Balling R, Nadeau JH. A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression. Human Molecular Genetics. 9: 227-36. PMID 10607833  0.56
1992 Glowka DA, Schafer DM, Scott DD, Wernig MD, Wright EK. Development and use of a return line flowmeter for lost circulation diagnosis in geothermal drilling Transactions - Geothermal Resources Council. 16: 39-46.  0.56
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