Pamela A. Silver - Publications

Affiliations: 
Systems Biology Harvard Medical School, Boston, MA, United States 
Area:
Intracellular Compartmentation
Website:
http://www.fas.harvard.edu/~biophys/Pamela_A_Silver.htm

247 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kim J, Zhou Y, Carlson PD, Teichmann M, Chaudhary S, Simmel FC, Silver PA, Collins JJ, Lucks JB, Yin P, Green AA. De novo-designed translation-repressing riboregulators for multi-input cellular logic. Nature Chemical Biology. PMID 31686032 DOI: 10.1038/s41589-019-0388-1  1
2019 Riglar DT, Richmond DL, Potvin-Trottier L, Verdegaal AA, Naydich AD, Bakshi S, Leoncini E, Lyon LG, Paulsson J, Silver PA. Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator. Nature Communications. 10: 4665. PMID 31604953 DOI: 10.1038/s41467-019-12638-z  1
2019 Ziesack M, Gibson T, Oliver JKW, Shumaker AM, Hsu BB, Riglar DT, Giessen TW, DiBenedetto NV, Bry L, Way JC, Silver PA, Gerber GK. Engineered Interspecies Amino Acid Cross-Feeding Increases Population Evenness in a Synthetic Bacterial Consortium. Msystems. 4. PMID 31409662 DOI: 10.1128/mSystems.00352-19  1
2019 Giessen TW, Orlando BJ, Verdegaal AA, Chambers MG, Gardener J, Bell DC, Birrane G, Liao M, Silver PA. Large protein organelles form a new iron sequestration system with high storage capacity. Elife. 8. PMID 31282860 DOI: 10.7554/eLife.46070  1
2019 Cristea IM, Dorrestein PC, Eisen JA, Gilbert JA, Huber JA, Jansson JK, Knight R, Pollard KS, Raes J, Silver PA, Webster NS, Xu J. Early-Career Scientists Shaping the World. Msystems. 4. PMID 31219787 DOI: 10.1128/mSystems.00196-19  1
2019 Naydich AD, Nangle SN, Bues JJ, Trivedi D, Nissar N, Inniss MC, Niederhuber MJ, Way JC, Silver PA, Riglar DT. Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface. Msystems. 4. PMID 31186335 DOI: 10.1128/mSystems.00125-19  1
2019 Tscherner M, Giessen TW, Markey L, Kumamoto C, Silver PA. A synthetic system that senses Candida albicans and inhibits virulence factors. Acs Synthetic Biology. PMID 30608638 DOI: 10.1021/acssynbio.8b00457  1
2018 Stirling F, Bitzan L, O'Keefe S, Redfield E, Oliver JWK, Way J, Silver PA. Rational Design of Evolutionarily Stable Microbial Kill Switches. Molecular Cell. 72: 395. PMID 30340025 DOI: 10.1016/j.molcel.2018.10.002  0.48
2018 Kim S, Kerns SJ, Ziesack M, Bry L, Gerber GK, Way JC, Silver PA. Quorum sensing can be repurposed to promote information transfer between bacteria in the mammalian gut. Acs Synthetic Biology. PMID 30125499 DOI: 10.1021/acssynbio.8b00271  0.68
2018 Spady ES, Wyche TP, Rollins NJ, Clardy J, Way JC, Silver PA. Mammalian Cells Engineered to Produce Novel Steroids. Chembiochem : a European Journal of Chemical Biology. PMID 29931794 DOI: 10.1002/cbic.201800214  0.68
2018 Lau YH, Giessen TW, Altenburg WJ, Silver PA. Prokaryotic nanocompartments form synthetic organelles in a eukaryote. Nature Communications. 9: 1311. PMID 29615617 DOI: 10.1038/s41467-018-03768-x  1
2018 Ziesack M, Rollins N, Shah A, Dusel B, Webster G, Silver PA, Way JC. Chimeric Fatty Acyl-ACP Thioesterases Provide Mechanistic Insight into Enzyme Specificity and Expression. Applied and Environmental Microbiology. PMID 29549102 DOI: 10.1128/AEM.02868-17  0.68
2018 Riglar DT, Silver PA. Engineering bacteria for diagnostic and therapeutic applications. Nature Reviews. Microbiology. PMID 29398705 DOI: 10.1038/nrmicro.2017.172  0.4
2017 Stirling F, Bitzan L, O'Keefe S, Redfield E, Oliver JWK, Way J, Silver PA. Rational Design of Evolutionarily Stable Microbial Kill Switches. Molecular Cell. 68: 686-697.e3. PMID 29149596 DOI: 10.1016/j.molcel.2017.10.033  0.48
2017 Nangle SN, Sakimoto KK, Silver PA, Nocera DG. Biological-inorganic hybrid systems as a generalized platform for chemical production. Current Opinion in Chemical Biology. 41: 107-113. PMID 29136557 DOI: 10.1016/j.cbpa.2017.10.023  0.4
2017 Kuo J, Stirling F, Lau YH, Shulgina Y, Way JC, Silver PA. Synthetic genome recoding: new genetic codes for new features. Current Genetics. PMID 28983660 DOI: 10.1007/s00294-017-0754-z  0.68
2017 Niederhuber MJ, Lambert TJ, Yapp C, Silver PA, Polka JK. Superresolution microscopy of the β-carboxysome reveals a homogeneous matrix. Molecular Biology of the Cell. 28: 2734-2745. PMID 28963440 DOI: 10.1091/mbc.E17-01-0069  1
2017 Niederhuber MJ, Lambert TJ, Yapp C, Silver PA, Polka JK. Super-resolution microscopy of the ß-carboxysome reveals a homogenous matrix. Molecular Biology of the Cell. PMID 28794262 DOI: 10.1091/mbc.E17-01-0069  1
2017 Green AA, Kim J, Ma D, Silver PA, Collins JJ, Yin P. Complex cellular logic computation using ribocomputing devices. Nature. PMID 28746304 DOI: 10.1038/nature23271  0.16
2017 Riglar DT, Giessen TW, Baym M, Kerns SJ, Niederhuber MJ, Bronson RT, Kotula JW, Gerber GK, Way JC, Silver PA. Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation. Nature Biotechnology. PMID 28553941 DOI: 10.1038/nbt.3879  1
2017 Lau YH, Stirling F, Kuo J, Karrenbelt MAP, Chan YA, Riesselman A, Horton CA, Schäfer E, Lips D, Weinstock MT, Gibson DG, Way JC, Silver PA. Large-scale recoding of a bacterial genome by iterative recombineering of synthetic DNA. Nucleic Acids Research. PMID 28499033 DOI: 10.1093/nar/gkx415  0.68
2017 Liu C, Nangle SN, Colón BC, Silver PA, Nocera DG. (13)C-Labeling the carbon-fixation pathway of a highly efficient artificial photosynthetic system. Faraday Discussions. PMID 28294218 DOI: 10.1039/c6fd00231e  0.4
2017 Giessen TW, Silver PA. Widespread distribution of encapsulin nanocompartments reveals functional diversity. Nature Microbiology. 2: 17029. PMID 28263314 DOI: 10.1038/nmicrobiol.2017.29  1
2017 Hays SG, Yan LL, Silver PA, Ducat DC. Synthetic photosynthetic consortia define interactions leading to robustness and photoproduction. Journal of Biological Engineering. 11: 4. PMID 28127397 DOI: 10.1186/s13036-017-0048-5  1
2017 Giessen TW, Silver PA. Engineering carbon fixation with artificial protein organelles. Current Opinion in Biotechnology. 46: 42-50. PMID 28126670 DOI: 10.1016/j.copbio.2017.01.004  1
2016 Brown DM, Chan YA, Desai PJ, Grzesik P, Oldfield LM, Vashee S, Way JC, Silver PA, Glass JI. Efficient size-independent chromosome delivery from yeast to cultured cell lines. Nucleic Acids Research. PMID 27980064 DOI: 10.1093/nar/gkw1252  0.68
2016 Liu X, Lopez PA, Giessen TW, Giles M, Way JC, Silver PA. Engineering Genetically-Encoded Mineralization and Magnetism via Directed Evolution. Scientific Reports. 6: 38019. PMID 27897245 DOI: 10.1038/srep38019  1
2016 Giessen TW, Silver PA. A Catalytic Nanoreactor Based on in Vivo Encapsulation of Multiple Enzymes in an Engineered Protein Nanocompartment. Chembiochem : a European Journal of Chemical Biology. PMID 27504846 DOI: 10.1002/cbic.201600431  1
2016 Myhrvold C, Polka JK, Silver PA. Synthetic Lipid-Containing Scaffolds Enhance Production by Colocalizing Enzymes. Acs Synthetic Biology. PMID 27487319 DOI: 10.1021/acssynbio.6b00141  1
2016 Lee JW, Gyorgy A, Cameron DE, Pyenson N, Choi KR, Way JC, Silver PA, Del Vecchio D, Collins JJ. Creating Single-Copy Genetic Circuits. Molecular Cell. PMID 27425413 DOI: 10.1016/j.molcel.2016.06.006  1
2016 Giessen TW, Silver PA. Converting a natural protein compartment into a nanofactory for the size-constrained synthesis of antimicrobial silver nanoparticles. Acs Synthetic Biology. PMID 27276075 DOI: 10.1021/acssynbio.6b00117  0.01
2016 Polka JK, Hays SG, Silver PA. Building Spatial Synthetic Biology with Compartments, Scaffolds, and Communities. Cold Spring Harbor Perspectives in Biology. PMID 27270297 DOI: 10.1101/cshperspect.a024018  1
2016 Boeke JD, Church G, Hessel A, Kelley NJ, Arkin A, Cai Y, Carlson R, Chakravarti A, Cornish VW, Holt L, Isaacs FJ, Kuiken T, Lajoie M, Lessor T, Lunshof J, ... ... Silver PA, et al. The Genome Project-Write. Science (New York, N.Y.). PMID 27256881 DOI: 10.1126/science.aaf6850  0.68
2016 Burrill DR, Vernet A, Collins JJ, Silver PA, Way JC. Targeted erythropoietin selectively stimulates red blood cell expansion in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114509 DOI: 10.1073/pnas.1525388113  1
2016 Liu X, Hicks WM, Silver PA, Way JC. Engineering acyl carrier protein to enhance production of shortened fatty acids. Biotechnology For Biofuels. 9: 24. PMID 26839587 DOI: 10.1186/s13068-016-0430-4  1
2016 MacKellar D, Lieber L, Norman JS, Bolger A, Tobin C, Murray JW, Oksaksin M, Chang RL, Ford TJ, Nguyen PQ, Woodward J, Permingeat HR, Joshi NS, Silver PA, Usadel B, et al. Streptomyces thermoautotrophicus does not fix nitrogen. Scientific Reports. 6: 20086. PMID 26833023 DOI: 10.1038/srep20086  1
2016 Polka JK, Silver PA. A tunable protein piston that breaks membranes to release encapsulated cargo. Acs Synthetic Biology. PMID 26814170 DOI: 10.1021/acssynbio.5b00237  1
2016 Biteen JS, Blainey PC, Cardon ZG, Chun M, Church GM, Dorrestein PC, Fraser SE, Gilbert JA, Jansson JK, Knight R, Miller JF, Ozcan A, Prather KA, Quake SR, Ruby EG, ... Silver PA, et al. Tools for the Microbiome: Nano and Beyond. Acs Nano. 10: 6-37. PMID 26695070 DOI: 10.1021/acsnano.5b07826  0.01
2015 Myhrvold C, Kotula JW, Hicks WM, Conway NJ, Silver PA. A distributed cell division counter reveals growth dynamics in the gut microbiota. Nature Communications. 6: 10039. PMID 26615910 DOI: 10.1038/ncomms10039  1
2015 Giessen TW, Silver PA. Encapsulation as a Strategy for the Design of Biological Compartmentalization. Journal of Molecular Biology. PMID 26403362 DOI: 10.1016/j.jmb.2015.09.009  1
2015 Hays SG, Patrick WG, Ziesack M, Oxman N, Silver PA. Better together: engineering and application of microbial symbioses. Current Opinion in Biotechnology. 36: 40-49. PMID 26319893 DOI: 10.1016/j.copbio.2015.08.008  1
2015 Chen AH, Lubkowicz D, Yeong V, Chang RL, Silver PA. Transplantability of a circadian clock to a noncircadian organism. Science Advances. 1. PMID 26229984 DOI: 10.1126/sciadv.1500358  0.6
2015 Ford TJ, Silver PA. Synthetic biology expands chemical control of microorganisms. Current Opinion in Chemical Biology. 28: 20-28. PMID 26056951 DOI: 10.1016/j.cbpa.2015.05.012  1
2015 Chang ZL, Silver PA, Chen YY. Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors. Journal of Translational Medicine. 13: 161. PMID 25990251 DOI: 10.1186/s12967-015-0519-8  1
2015 Torella JP, Gagliardi CJ, Chen JS, Bediako DK, Colón B, Way JC, Silver PA, Nocera DG. Efficient solar-to-fuels production from a hybrid microbial-water-splitting catalyst system. Proceedings of the National Academy of Sciences of the United States of America. 112: 2337-42. PMID 25675518 DOI: 10.1073/pnas.1424872112  0.68
2015 Myhrvold C, Silver PA. Using synthetic RNAs as scaffolds and regulators. Nature Structural & Molecular Biology. 22: 8-10. PMID 25565027 DOI: 10.1038/nsmb.2944  1
2015 Torella JP, Gagliardi CJ, Chen JS, Bediako DK, Colón B, Way JC, Silver PA, Nocera DG. Correction: Efficient solar-to-fuels production from a hybrid microbial - Water-splitting catalyst system (Proc Natl Acad Sci USA (2015) 112 (2337-2342) 10.1073/pnas.1424872112) Proceedings of the National Academy of Sciences of the United States of America. 112: E1507. DOI: 10.1073/pnas.1503606112  0.68
2015 Hays SG, Patrick WG, Ziesack M, Oxman N, Silver PA. Better together: Engineering and application of microbial symbioses Current Opinion in Biotechnology. 36: 40-49. DOI: 10.1016/j.copbio.2015.08.008  1
2014 Robinson-Mosher A, Chen JH, Way J, Silver PA. Designing cell-targeted therapeutic proteins reveals the interplay between domain connectivity and cell binding. Biophysical Journal. 107: 2456-66. PMID 25418314 DOI: 10.1016/j.bpj.2014.10.007  1
2014 Green AA, Silver PA, Collins JJ, Yin P. Toehold switches: de-novo-designed regulators of gene expression. Cell. 159: 925-39. PMID 25417166 DOI: 10.1016/j.cell.2014.10.002  1
2014 Polka JK, Silver PA. Induced sensitivity of Bacillus subtilis colony morphology to mechanical media compression. Peerj. 2: e597. PMID 25289183 DOI: 10.7717/peerj.597  1
2014 Torella JP, Lienert F, Boehm CR, Chen JH, Way JC, Silver PA. Unique nucleotide sequence-guided assembly of repetitive DNA parts for synthetic biology applications. Nature Protocols. 9: 2075-89. PMID 25101822 DOI: 10.1038/nprot.2014.145  1
2014 Sachdeva G, Garg A, Godding D, Way JC, Silver PA. In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner. Nucleic Acids Research. 42: 9493-503. PMID 25034694 DOI: 10.1093/nar/gku617  1
2014 Silver PA, Way JC, Arnold FH, Meyerowitz JT. Synthetic biology: Engineering explored. Nature. 509: 166-7. PMID 24805338 DOI: 10.1038/509166a  1
2014 Mattozzi MD, Voges MJ, Silver PA, Way JC. Transient gene expression in tobacco using Gibson assembly and the Gene Gun. Journal of Visualized Experiments : Jove. PMID 24796418 DOI: 10.3791/51234  1
2014 Way JC, Collins JJ, Keasling JD, Silver PA. Integrating biological redesign: where synthetic biology came from and where it needs to go. Cell. 157: 151-61. PMID 24679533 DOI: 10.1016/j.cell.2014.02.039  1
2014 Kotula JW, Kerns SJ, Shaket LA, Siraj L, Collins JJ, Way JC, Silver PA. Programmable bacteria detect and record an environmental signal in the mammalian gut. Proceedings of the National Academy of Sciences of the United States of America. 111: 4838-43. PMID 24639514 DOI: 10.1073/pnas.1321321111  1
2014 Weyn-Vanhentenryck SM, Mele A, Yan Q, Sun S, Farny N, Zhang Z, Xue C, Herre M, Silver PA, Zhang MQ, Krainer AR, Darnell RB, Zhang C. HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism. Cell Reports. 6: 1139-52. PMID 24613350 DOI: 10.1016/j.celrep.2014.02.005  1
2014 Lienert F, Lohmueller JJ, Garg A, Silver PA. Synthetic biology in mammalian cells: next generation research tools and therapeutics. Nature Reviews. Molecular Cell Biology. 15: 95-107. PMID 24434884 DOI: 10.1038/nrm3738  1
2014 Torella JP, Boehm CR, Lienert F, Chen JH, Way JC, Silver PA. Rapid construction of insulated genetic circuits via synthetic sequence-guided isothermal assembly. Nucleic Acids Research. 42: 681-9. PMID 24078086 DOI: 10.1093/nar/gkt860  1
2013 Polka JK, Silver PA. Building synthetic cellular organization. Molecular Biology of the Cell. 24: 3585-7. PMID 24288075 DOI: 10.1091/mbc.E13-03-0155  1
2013 Wintermute EH, Lieberman TD, Silver PA. An objective function exploiting suboptimal solutions in metabolic networks. Bmc Systems Biology. 7: 98. PMID 24088221 DOI: 10.1186/1752-0509-7-98  1
2013 Inniss MC, Silver PA. Building synthetic memory. Current Biology : Cb. 23: R812-6. PMID 24028965 DOI: 10.1016/j.cub.2013.06.047  1
2013 Chen AH, Robinson-Mosher A, Savage DF, Silver PA, Polka JK. The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo. Plos One. 8: e76127. PMID 24023971 DOI: 10.1371/journal.pone.0076127  1
2013 Voges MJ, Silver PA, Way JC, Mattozzi MD. Targeting a heterologous protein to multiple plant organelles via rationally designed 5' mRNA tags. Journal of Biological Engineering. 7: 20. PMID 24011257 DOI: 10.1186/1754-1611-7-20  1
2013 Lienert F, Torella JP, Chen JH, Norsworthy M, Richardson RR, Silver PA. Two- and three-input TALE-based AND logic computation in embryonic stem cells. Nucleic Acids Research. 41: 9967-75. PMID 23982518 DOI: 10.1093/nar/gkt758  1
2013 Myhrvold C, Dai M, Silver PA, Yin P. Isothermal self-assembly of complex DNA structures under diverse and biocompatible conditions. Nano Letters. 13: 4242-8. PMID 23978049 DOI: 10.1021/nl4019512  1
2013 Robinson-Mosher A, Shinar T, Silver PA, Way J. Dynamics simulations for engineering macromolecular interactions. Chaos (Woodbury, N.Y.). 23: 025110. PMID 23822508 DOI: 10.1063/1.4810915  1
2013 Torella JP, Ford TJ, Kim SN, Chen AM, Way JC, Silver PA. Tailored fatty acid synthesis via dynamic control of fatty acid elongation. Proceedings of the National Academy of Sciences of the United States of America. 110: 11290-5. PMID 23798438 DOI: 10.1073/pnas.1307129110  1
2013 Selgrade DF, Lohmueller JJ, Lienert F, Silver PA. Protein scaffold-activated protein trans-splicing in mammalian cells. Journal of the American Chemical Society. 135: 7713-9. PMID 23621664 DOI: 10.1021/ja401689b  1
2013 Wang Q, Moore MJ, Adelmant G, Marto JA, Silver PA. PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth. Genes & Development. 27: 615-26. PMID 23512658 DOI: 10.1101/gad.212308.112  1
2013 Mattozzi Md, Ziesack M, Voges MJ, Silver PA, Way JC. Expression of the sub-pathways of the Chloroflexus aurantiacus 3-hydroxypropionate carbon fixation bicycle in E. coli: Toward horizontal transfer of autotrophic growth. Metabolic Engineering. 16: 130-9. PMID 23376595 DOI: 10.1016/j.ymben.2013.01.005  1
2013 Ford TJ, Silver P. Rephrasing the biofuel question Microbe. 8: 59-64.  1
2013 Green AA, Silver P, Collins JJ, Yin P. Highly orthogonal programmable riboregulators for complex digital logic in E. Coli Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 233-234.  1
2012 Chen AH, Afonso B, Silver PA, Savage DF. Spatial and temporal organization of chromosome duplication and segregation in the cyanobacterium Synechococcus elongatus PCC 7942. Plos One. 7: e47837. PMID 23112856 DOI: 10.1371/journal.pone.0047837  1
2012 Delebecque CJ, Silver PA, Lindner AB. Designing and using RNA scaffolds to assemble proteins in vivo. Nature Protocols. 7: 1797-807. PMID 22955695 DOI: 10.1038/nprot.2012.102  1
2012 Chen AH, Silver PA. Designing biological compartmentalization. Trends in Cell Biology. 22: 662-70. PMID 22841504 DOI: 10.1016/j.tcb.2012.07.002  1
2012 Burrill DR, Inniss MC, Boyle PM, Silver PA. Synthetic memory circuits for tracking human cell fate. Genes & Development. 26: 1486-97. PMID 22751502 DOI: 10.1101/gad.189035.112  1
2012 Chen AJ, Paik JH, Zhang H, Shukla SA, Mortensen R, Hu J, Ying H, Hu B, Hurt J, Farny N, Dong C, Xiao Y, Wang YA, Silver PA, Chin L, et al. STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA. Genes & Development. 26: 1459-72. PMID 22751500 DOI: 10.1101/gad.189001.112  1
2012 Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, Dewerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, ... ... Silver PA, et al. A BioBrick compatible strategy for genetic modification of plants. Journal of Biological Engineering. 6: 8. PMID 22716313 DOI: 10.1186/1754-1611-6-8  1
2012 Ducat DC, Silver PA. Improving carbon fixation pathways. Current Opinion in Chemical Biology. 16: 337-44. PMID 22647231 DOI: 10.1016/j.cbpa.2012.05.002  1
2012 Agapakis CM, Boyle PM, Silver PA. Natural strategies for the spatial optimization of metabolism in synthetic biology. Nature Chemical Biology. 8: 527-35. PMID 22596204 DOI: 10.1038/nchembio.975  1
2012 Garg A, Lohmueller JJ, Silver PA, Armel TZ. Engineering synthetic TAL effectors with orthogonal target sites. Nucleic Acids Research. 40: 7584-95. PMID 22581776 DOI: 10.1093/nar/gks404  1
2012 Adelmant G, Calkins AS, Garg BK, Card JD, Askenazi M, Miron A, Sobhian B, Zhang Y, Nakatani Y, Silver PA, Iglehart JD, Marto JA, Lazaro JB. DNA ends alter the molecular composition and localization of Ku multicomponent complexes. Molecular & Cellular Proteomics : McP. 11: 411-21. PMID 22535209 DOI: 10.1074/mcp.M111.013581  1
2012 Haynes KA, Ceroni F, Flicker D, Younger A, Silver PA. A sensitive switch for visualizing natural gene silencing in single cells. Acs Synthetic Biology. 1: 99-106. PMID 22530199 DOI: 10.1021/sb3000035  1
2012 Nishida K, Silver PA. Induction of biogenic magnetization and redox control by a component of the target of rapamycin complex 1 signaling pathway. Plos Biology. 10: e1001269. PMID 22389629 DOI: 10.1371/journal.pbio.1001269  1
2012 Lohmueller JJ, Armel TZ, Silver PA. A tunable zinc finger-based framework for Boolean logic computation in mammalian cells. Nucleic Acids Research. 40: 5180-7. PMID 22323524 DOI: 10.1093/nar/gks142  1
2012 Ducat DC, Avelar-Rivas JA, Way JC, Silver PA. Rerouting carbon flux to enhance photosynthetic productivity. Applied and Environmental Microbiology. 78: 2660-8. PMID 22307292 DOI: 10.1128/AEM.07901-11  1
2012 Bonacci W, Teng PK, Afonso B, Niederholtmeyer H, Grob P, Silver PA, Savage DF. Modularity of a carbon-fixing protein organelle. Proceedings of the National Academy of Sciences of the United States of America. 109: 478-83. PMID 22184212 DOI: 10.1073/pnas.1108557109  1
2012 Boyle PM, Silver PA. Parts plus pipes: synthetic biology approaches to metabolic engineering. Metabolic Engineering. 14: 223-32. PMID 22037345 DOI: 10.1016/j.ymben.2011.10.003  1
2012 Silver PA, Haynes K, Weiss R. Synthetic meets cell biology Molecular Biology of the Cell. 23: 967. DOI: 10.1091/mbc.E11-12-0978  1
2012 Lentzos F, Silver P. Synthesis of viral genomes Innovation Dual Use and Security: Managing the Risks of Emerging Biological and Chemical Technologies. 133-146.  1
2011 Burrill DR, Boyle PM, Silver PA. A new approach to an old problem: synthetic biology tools for human disease and metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 145-54. PMID 22169233 DOI: 10.1101/sqb.2011.76.010686  1
2011 Waks Z, Klein AM, Silver PA. Cell-to-cell variability of alternative RNA splicing. Molecular Systems Biology. 7: 506. PMID 21734645 DOI: 10.1038/msb.2011.32  1
2011 Delebecque CJ, Lindner AB, Silver PA, Aldaye FA. Organization of intracellular reactions with rationally designed RNA assemblies. Science (New York, N.Y.). 333: 470-4. PMID 21700839 DOI: 10.1126/science.1206938  1
2011 Burrill DR, Silver PA. Recording cellular experiences of DNA damage. Cell Cycle (Georgetown, Tex.). 10: 2410-1. PMID 21670599 DOI: 10.4161/cc.10.15.16384  1
2011 Haynes KA, Silver PA. Synthetic reversal of epigenetic silencing. The Journal of Biological Chemistry. 286: 27176-82. PMID 21669865 DOI: 10.1074/jbc.C111.229567  1
2011 Shih JD, Waks Z, Kedersha N, Silver PA. Visualization of single mRNAs reveals temporal association of proteins with microRNA-regulated mRNA. Nucleic Acids Research. 39: 7740-9. PMID 21653551 DOI: 10.1093/nar/gkr456  1
2011 Barstow B, Agapakis CM, Boyle PM, Grandl G, Silver PA, Wintermute EH. A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism. Journal of Biological Engineering. 5: 7. PMID 21615937 DOI: 10.1186/1754-1611-5-7  1
2011 Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC, Silver PA. Towards a synthetic chloroplast. Plos One. 6: e18877. PMID 21533097 DOI: 10.1371/journal.pone.0018877  1
2011 Senapedis WT, Kennedy CJ, Boyle PM, Silver PA. Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. Molecular Biology of the Cell. 22: 1791-805. PMID 21460183 DOI: 10.1091/mbc.E10-10-0854  1
2011 Smolke CD, Silver PA. Informing biological design by integration of systems and synthetic biology. Cell. 144: 855-9. PMID 21414477 DOI: 10.1016/j.cell.2011.02.020  1
2011 Ducat DC, Sachdeva G, Silver PA. Rewiring hydrogenase-dependent redox circuits in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America. 108: 3941-6. PMID 21368150 DOI: 10.1073/pnas.1016026108  1
2011 Burrill DR, Silver PA. Synthetic circuit identifies subpopulations with sustained memory of DNA damage. Genes & Development. 25: 434-9. PMID 21363961 DOI: 10.1101/gad.1994911  1
2011 Ducat DC, Way JC, Silver PA. Engineering cyanobacteria to generate high-value products. Trends in Biotechnology. 29: 95-103. PMID 21211860 DOI: 10.1016/j.tibtech.2010.12.003  1
2011 Way JC, Silver PA, Howard RJ. Sun-driven microbial synthesis of chemicals in space International Journal of Astrobiology. 10: 359-364. DOI: 10.1017/S1473550411000218  1
2010 Agapakis CM, Silver PA. Modular electron transfer circuits for synthetic biology: insulation of an engineered biohydrogen pathway. Bioengineered Bugs. 1: 413-8. PMID 21468209 DOI: 10.4161/bbug.1.6.12462  0.76
2010 Waks Z, Silver PA. Nuclear origins of cell-to-cell variability. Cold Spring Harbor Symposia On Quantitative Biology. 75: 87-94. PMID 21447820 DOI: 10.1101/sqb.2010.75.027  1
2010 Wintermute EH, Silver PA. Dynamics in the mixed microbial concourse. Genes & Development. 24: 2603-14. PMID 21123647 DOI: 10.1101/gad.1985210  1
2010 Wang Q, Silver PA. Genome-wide RNAi screen discovers functional coupling of alternative splicing and cell cycle control to apoptosis regulation. Cell Cycle (Georgetown, Tex.). 9: 4419-21. PMID 21088477 DOI: 10.4161/cc.9.22.14051  1
2010 Aldaye FA, Senapedis WT, Silver PA, Way JC. A structurally tunable DNA-based extracellular matrix. Journal of the American Chemical Society. 132: 14727-9. PMID 20925350 DOI: 10.1021/ja105431h  1
2010 Wintermute EH, Silver PA. Emergent cooperation in microbial metabolism. Molecular Systems Biology. 6: 407. PMID 20823845 DOI: 10.1038/msb.2010.66  1
2010 Moore MJ, Wang Q, Kennedy CJ, Silver PA. An alternative splicing network links cell-cycle control to apoptosis. Cell. 142: 625-36. PMID 20705336 DOI: 10.1016/j.cell.2010.07.019  1
2010 Silver PA. Knowing when to change: reprogramming (my) life. Nature Cell Biology. 12: 730. PMID 20680000 DOI: 10.1038/ncb0810-730  1
2010 Niederholtmeyer H, Wolfstädter BT, Savage DF, Silver PA, Way JC. Engineering cyanobacteria to synthesize and export hydrophilic products. Applied and Environmental Microbiology. 76: 3462-6. PMID 20363793 DOI: 10.1128/AEM.00202-10  1
2010 Savage DF, Afonso B, Chen AH, Silver PA. Spatially ordered dynamics of the bacterial carbon fixation machinery. Science (New York, N.Y.). 327: 1258-61. PMID 20203050 DOI: 10.1126/science.1186090  1
2010 Agapakis CM, Ducat DC, Boyle PM, Wintermute EH, Way JC, Silver PA. Insulation of a synthetic hydrogen metabolism circuit in bacteria. Journal of Biological Engineering. 4: 3. PMID 20184755 DOI: 10.1186/1754-1611-4-3  1
2010 Afonso B, Silver PA, Ajo-Franklin CM. A synthetic circuit for selectively arresting daughter cells to create aging populations. Nucleic Acids Research. 38: 2727-35. PMID 20150416 DOI: 10.1093/nar/gkq075  1
2010 Burrill DR, Silver PA. Making cellular memories. Cell. 140: 13-8. PMID 20085698 DOI: 10.1016/j.cell.2009.12.034  1
2010 Taylor ND, Way JC, Silver PA, Cironi P. Anti-glycophorin single-chain Fv fusion to low-affinity mutant erythropoietin improves red blood cell-lineage specificity. Protein Engineering, Design & Selection : Peds. 23: 251-60. PMID 20083493 DOI: 10.1093/protein/gzp085  1
2009 Haynes KA, Silver PA. Eukaryotic systems broaden the scope of synthetic biology. The Journal of Cell Biology. 187: 589-96. PMID 19948487 DOI: 10.1083/jcb.200908138  1
2009 Farny NG, Kedersha NL, Silver PA. Metazoan stress granule assembly is mediated by P-eIF2alpha-dependent and -independent mechanisms. Rna (New York, N.Y.). 15: 1814-21. PMID 19661161 DOI: 10.1261/rna.1684009  1
2009 Kennedy CJ, Boyle PM, Waks Z, Silver PA. Systems-level engineering of nonfermentative metabolism in yeast. Genetics. 183: 385-97. PMID 19564482 DOI: 10.1534/genetics.109.105254  1
2009 Agapakis CM, Silver PA. Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks. Molecular Biosystems. 5: 704-13. PMID 19562109 DOI: 10.1039/b901484e  1
2009 Hurt JA, Obar RA, Zhai B, Farny NG, Gygi SP, Silver PA. A conserved CCCH-type zinc finger protein regulates mRNA nuclear adenylation and export. The Journal of Cell Biology. 185: 265-77. PMID 19364924 DOI: 10.1083/jcb.200811072  1
2009 Boyle PM, Silver PA. Harnessing nature's toolbox: regulatory elements for synthetic biology. Journal of the Royal Society, Interface / the Royal Society. 6: S535-46. PMID 19324675 DOI: 10.1098/rsif.2008.0521.focus  1
2009 Waks Z, Silver PA. Engineering a synthetic dual-organism system for hydrogen production. Applied and Environmental Microbiology. 75: 1867-75. PMID 19201964 DOI: 10.1128/AEM.02009-08  1
2009 Lee SI, Dudley AM, Drubin D, Silver PA, Krogan NJ, Pe'er D, Koller D. Learning a prior on regulatory potential from eQTL data. Plos Genetics. 5: e1000358. PMID 19180192 DOI: 10.1371/journal.pgen.1000358  1
2008 Hurt JA, Silver PA. mRNA nuclear export and human disease. Disease Models & Mechanisms. 1: 103-8. PMID 19048072 DOI: 10.1242/dmm.000745  1
2008 Swinburne IA, Miguez DG, Landgraf D, Silver PA. Intron length increases oscillatory periods of gene expression in animal cells. Genes & Development. 22: 2342-6. PMID 18703678 DOI: 10.1101/gad.1696108  1
2008 Swinburne IA, Silver PA. Intron delays and transcriptional timing during development. Developmental Cell. 14: 324-30. PMID 18331713 DOI: 10.1016/j.devcel.2008.02.002  1
2008 Brown CR, Kennedy CJ, Delmar VA, Forbes DJ, Silver PA. Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes & Development. 22: 627-39. PMID 18316479 DOI: 10.1101/gad.1632708  1
2008 Cironi P, Swinburne IA, Silver PA. Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. The Journal of Biological Chemistry. 283: 8469-76. PMID 18230610 DOI: 10.1074/jbc.M708502200  1
2008 Savage DF, Way J, Silver PA. Defossiling fuel: how synthetic biology can transform biofuel production. Acs Chemical Biology. 3: 13-6. PMID 18205286 DOI: 10.1021/cb700259j  1
2008 Frietze S, Lupien M, Silver PA, Brown M. CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1. Cancer Research. 68: 301-6. PMID 18172323 DOI: 10.1158/0008-5472.CAN-07-1983  1
2008 Farny NG, Hurt JA, Silver PA. Definition of global and transcript-specific mRNA export pathways in metazoans. Genes & Development. 22: 66-78. PMID 18086857 DOI: 10.1101/gad.1616008  1
2008 Moore MJ, Silver PA. Global analysis of mRNA splicing. Rna (New York, N.Y.). 14: 197-203. PMID 18083834 DOI: 10.1261/rna.868008  1
2008 Komili S, Silver PA. Coupling and coordination in gene expression processes: a systems biology view. Nature Reviews. Genetics. 9: 38-48. PMID 18071322 DOI: 10.1038/nrg2223  1
2007 Komili S, Farny NG, Roth FP, Silver PA. Functional specificity among ribosomal proteins regulates gene expression. Cell. 131: 557-71. PMID 17981122 DOI: 10.1016/j.cell.2007.08.037  1
2007 Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EP, Landgraf D, Phillips I, Silver PA. Rational design of memory in eukaryotic cells. Genes & Development. 21: 2271-6. PMID 17875664 DOI: 10.1101/gad.1586107  1
2007 McKee AE, Neretti N, Carvalho LE, Meyer CA, Fox EA, Brodsky AS, Silver PA. Exon expression profiling reveals stimulus-mediated exon use in neural cells. Genome Biology. 8: R159. PMID 17683528 DOI: 10.1186/gb-2007-8-8-r159  1
2007 Silver PA, Way JC. Molecular systems biology in drug development. Clinical Pharmacology and Therapeutics. 82: 586-90. PMID 17637784 DOI: 10.1038/sj.clpt.6100293  1
2007 McKee AE, Silver PA. Systems perspectives on mRNA processing. Cell Research. 17: 581-90. PMID 17621309 DOI: 10.1038/cr.2007.54  1
2007 Zhou Z, Cironi P, Lin AJ, Xu Y, Hrvatin S, Golan DE, Silver PA, Walsh CT, Yin J. Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases. Acs Chemical Biology. 2: 337-46. PMID 17465518 DOI: 10.1021/cb700054k  1
2007 Brown CR, Silver PA. Transcriptional regulation at the nuclear pore complex. Current Opinion in Genetics & Development. 17: 100-6. PMID 17317147 DOI: 10.1016/j.gde.2007.02.005  1
2007 Drubin DA, Way JC, Silver PA. Designing biological systems. Genes & Development. 21: 242-54. PMID 17289915 DOI: 10.1101/gad.1507207  1
2007 Arbiser JL, Kau T, Konar M, Narra K, Ramchandran R, Summers SA, Vlahos CJ, Ye K, Perry BN, Matter W, Fischl A, Cook J, Silver PA, Bain J, Cohen P, et al. Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis. Blood. 109: 560-5. PMID 16990598 DOI: 10.1182/blood-2006-06-029934  1
2007 Way JC, Silver PA. Systems engineering without an engineer: Why we need systems biology Complexity. 13: 22-29. DOI: 10.1002/cplx.20198  1
2006 Yu MC, Lamming DW, Eskin JA, Sinclair DA, Silver PA. The role of protein arginine methylation in the formation of silent chromatin. Genes & Development. 20: 3249-54. PMID 17158743 DOI: 10.1101/gad.1495206  1
2006 Gama-Carvalho M, Barbosa-Morais NL, Brodsky AS, Silver PA, Carmo-Fonseca M. Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors. Genome Biology. 7: R113. PMID 17137510 DOI: 10.1186/gb-2006-7-11-r113  1
2006 Tsankov AM, Brown CR, Yu MC, Win MZ, Silver PA, Casolari JM. Communication between levels of transcriptional control improves robustness and adaptivity. Molecular Systems Biology. 2: 65. PMID 17130867 DOI: 10.1038/msb4100106  1
2006 Goffin L, Vodala S, Fraser C, Ryan J, Timms M, Meusburger S, Catimel B, Nice EC, Silver PA, Xiao CY, Jans DA, Gething MJ. The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins. Molecular Biology of the Cell. 17: 5309-23. PMID 17035634 DOI: 10.1091/mbc.E06-04-0292  1
2006 Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, et al. Genome-wide analysis of estrogen receptor binding sites. Nature Genetics. 38: 1289-97. PMID 17013392 DOI: 10.1038/ng1901  1
2006 Auld KL, Silver PA. Transcriptional regulation by the proteasome as a mechanism for cellular protein homeostasis. Cell Cycle (Georgetown, Tex.). 5: 1503-5. PMID 16861887  1
2006 Auld KL, Hitchcock AL, Doherty HK, Frietze S, Huang LS, Silver PA. The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae. Genetics. 174: 215-27. PMID 16816426 DOI: 10.1534/genetics.106.058362  1
2006 Swinburne IA, Meyer CA, Liu XS, Silver PA, Brodsky AS. Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription. Genome Research. 16: 912-21. PMID 16769980 DOI: 10.1101/gr.5211806  1
2006 McKee AE, Silver PA. Systems biology of gene regulation fulfills its promise. Genome Biology. 7: 316. PMID 16719937 DOI: 10.1186/gb-2006-7-5-316  1
2006 Brown CR, Silver PA. Pore-ing the right dose. Nature Cell Biology. 8: 430-1. PMID 16691206 DOI: 10.1038/ncb0506-430  1
2006 Drubin DA, Garakani AM, Silver PA. Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics. Bmc Cell Biology. 7: 19. PMID 16635267 DOI: 10.1186/1471-2121-7-19  1
2006 Auld KL, Brown CR, Casolari JM, Komili S, Silver PA. Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates. Molecular Cell. 21: 861-71. PMID 16543154 DOI: 10.1016/j.molcel.2006.02.020  1
2006 Bachand F, Lackner DH, Bähler J, Silver PA. Autoregulation of ribosome biosynthesis by a translational response in fission yeast. Molecular and Cellular Biology. 26: 1731-42. PMID 16478994 DOI: 10.1128/MCB.26.5.1731-1742.2006  1
2006 Hitchcock AL, Kahana JA, Silver PA. The uses of green fluorescent protein in yeasts. Methods of Biochemical Analysis. 47: 179-201. PMID 16335714 DOI: 10.1002/0471739499.ch9  1
2005 Robinson MA, Park S, Sun ZY, Silver PA, Wagner G, Hogle JM. Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p. The Journal of Biological Chemistry. 280: 35723-32. PMID 16105837 DOI: 10.1074/jbc.M505068200  1
2005 Brodsky AS, Meyer CA, Swinburne IA, Hall G, Keenan BJ, Liu XS, Fox EA, Silver PA. Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells. Genome Biology. 6: R64. PMID 16086846 DOI: 10.1186/gb-2005-6-8-r64  1
2005 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. Bmc Developmental Biology. 5: 14. PMID 16033648 DOI: 10.1186/1471-213X-5-14  1
2005 Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell. 122: 33-43. PMID 16009131 DOI: 10.1016/j.cell.2005.05.008  1
2005 Park S, Isaacson R, Kim HT, Silver PA, Wagner G. Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites. Structure (London, England : 1993). 13: 995-1005. PMID 16004872 DOI: 10.1016/j.str.2005.04.013  1
2005 Casolari JM, Brown CR, Drubin DA, Rando OJ, Silver PA. Developmentally induced changes in transcriptional program alter spatial organization across chromosomes. Genes & Development. 19: 1188-98. PMID 15905407 DOI: 10.1101/gad.1307205  1
2005 Schroeder FC, Kau TR, Silver PA, Clardy J. The psammaplysenes, specific inhibitors of FOXO1a nuclear export. Journal of Natural Products. 68: 574-6. PMID 15844952 DOI: 10.1021/np049624z  1
2004 Hieronymus H, Silver PA. A systems view of mRNP biology. Genes & Development. 18: 2845-60. PMID 15574591 DOI: 10.1101/gad.1256904  1
2004 Hieronymus H, Yu MC, Silver PA. Genome-wide mRNA surveillance is coupled to mRNA export. Genes & Development. 18: 2652-62. PMID 15489286 DOI: 10.1101/gad.1241204  1
2004 Yu MC, Bachand F, McBride AE, Komili S, Casolari JM, Silver PA. Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors. Genes & Development. 18: 2024-35. PMID 15314027 DOI: 10.1101/gad.1223204  1
2004 McKee AE, Silver PA. REF-ereeing the cytoplasmic fate of mRNA via nuclear export. Developmental Cell. 6: 740-2. PMID 15177019 DOI: 10.1016/j.devcel.2004.05.014  1
2004 Bachand F, Silver PA. PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits. The Embo Journal. 23: 2641-50. PMID 15175657 DOI: 10.1038/sj.emboj.7600265  1
2004 Casolari JM, Brown CR, Komili S, West J, Hieronymus H, Silver PA. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell. 117: 427-39. PMID 15137937 DOI: 10.1016/S0092-8674(04)00448-9  1
2004 Casolari JM, Silver PA. Guardian at the gate: preventing unspliced pre-mRNA export. Trends in Cell Biology. 14: 222-5. PMID 15130577 DOI: 10.1016/j.tcb.2004.03.007  1
2004 Devroe E, Erdjument-Bromage H, Tempst P, Silver PA. Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases. The Journal of Biological Chemistry. 279: 24444-51. PMID 15067004 DOI: 10.1074/jbc.M401999200  1
2004 Devroe E, Silver PA. Therapeutic potential of retroviral RNAi vectors. Expert Opinion On Biological Therapy. 4: 319-27. PMID 15006726 DOI: 10.1517/14712598.4.3.319  1
2004 Kau TR, Way JC, Silver PA. Nuclear transport and cancer: from mechanism to intervention. Nature Reviews. Cancer. 4: 106-17. PMID 14732865 DOI: 10.1038/nrc1274  1
2004 Jiang Y, Minet E, Zhang Z, Silver PA, Bai M. Modulation of interprotomer relationships is important for activation of dimeric calcium-sensing receptor. The Journal of Biological Chemistry. 279: 14147-56. PMID 14729680 DOI: 10.1074/jbc.M307422200  1
2003 Kau TR, Schroeder F, Ramaswamy S, Wojciechowski CL, Zhao JJ, Roberts TM, Clardy J, Sellers WR, Silver PA. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell. 4: 463-76. PMID 14706338 DOI: 10.1016/S1535-6108(03)00303-9  1
2003 Haggarty SJ, Koeller KM, Kau TR, Silver PA, Roberge M, Schreiber SL. Small molecule modulation of the human chromatid decatenation checkpoint. Chemistry & Biology. 10: 1267-79. PMID 14700634 DOI: 10.1016/j.chembiol.2003.11.014  1
2003 Hitchcock AL, Auld K, Gygi SP, Silver PA. A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery. Proceedings of the National Academy of Sciences of the United States of America. 100: 12735-40. PMID 14557538 DOI: 10.1073/pnas.2135500100  1
2003 Brodsky AS, Johnston AP, Trau M, Silver PA. Analysis of RNA-protein interactions by flow cytometry. Current Opinion in Molecular Therapeutics. 5: 235-40. PMID 12870432  1
2003 Lei EP, Stern CA, Fahrenkrog B, Krebber H, Moy TI, Aebi U, Silver PA. Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex. Molecular Biology of the Cell. 14: 836-47. PMID 12631707 DOI: 10.1091/mbc.E02-08-0520  1
2003 Kau TR, Silver PA. Nuclear transport as a target for cell growth. Drug Discovery Today. 8: 78-85. PMID 12565010 DOI: 10.1016/S1359-6446(02)02562-X  1
2003 Hieronymus H, Silver PA. Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery. Nature Genetics. 33: 155-61. PMID 12524544 DOI: 10.1038/ng1080  1
2003 Beilharz T, Egan B, Silver PA, Hofmann K, Lithgow T. Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 278: 8219-23. PMID 12514182 DOI: 10.1074/jbc.M212725200  1
2002 Brodsky AS, Silver PA. A microbead-based system for identifying and characterizing RNA-protein interactions by flow cytometry. Molecular & Cellular Proteomics : McP. 1: 922-9. PMID 12543929  1
2002 Damelin M, Silver PA. In situ analysis of spatial relationships between proteins of the nuclear pore complex. Biophysical Journal. 83: 3626-36. PMID 12496130 DOI: 10.1016/S0006-3495(02)75363-0  1
2002 Lei EP, Silver PA. Intron status and 3'-end formation control cotranscriptional export of mRNA. Genes & Development. 16: 2761-6. PMID 12414728 DOI: 10.1101/gad.1032902  1
2002 Devroe E, Silver PA. Retrovirus-delivered siRNA. Bmc Biotechnology. 2: 15. PMID 12199908 DOI: 10.1186/1472-6750-2-15  1
2002 Moy TI, Silver PA. Requirements for the nuclear export of the small ribosomal subunit. Journal of Cell Science. 115: 2985-95. PMID 12082158  1
2002 Damelin M, Silver PA, Corbett AH. Nuclear protein transport. Methods in Enzymology. 351: 587-607. PMID 12073370 DOI: 10.1016/S0076-6879(02)51870-X  1
2002 Brodsky AS, Silver PA. Identifying proteins that affect mRNA localization in living cells. Methods (San Diego, Calif.). 26: 151-5. PMID 12054891 DOI: 10.1016/S1046-2023(02)00017-8  1
2002 Moy TI, Boettner D, Rhodes JC, Silver PA, Askew DS. Identification of a role for Saccharomyces cerevisiae Cgr1p in pre-rRNA processing and 60S ribosome subunit synthesis. Microbiology (Reading, England). 148: 1081-90. PMID 11932453 DOI: 10.1099/00221287-148-4-1081  1
2002 Damelin M, Simon I, Moy TI, Wilson B, Komili S, Tempst P, Roth FP, Young RA, Cairns BR, Silver PA. The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Molecular Cell. 9: 563-73. PMID 11931764 DOI: 10.1016/S1097-2765(02)00475-6  1
2002 Lei EP, Silver PA. Protein and RNA export from the nucleus. Developmental Cell. 2: 261-72. PMID 11879632 DOI: 10.1016/S1534-5807(02)00134-X  1
2002 Valentini SR, Casolari JM, Oliveira CC, Silver PA, McBride AE. Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics. 160: 393-405. PMID 11861547  1
2001 Kahana JA, Silver PA. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 6.6. PMID 21965077 DOI: 10.1002/0471141755.ph0606s05  1
2001 Kahana JA, Silver PA. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.15. PMID 18428498 DOI: 10.1002/0471142301.ns0515s14  1
2001 Kahana JA, Silver PA. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit9.7C. PMID 18265287 DOI: 10.1002/0471142727.mb0907cs34  1
2001 Hitchcock AL, Krebber H, Frietze S, Lin A, Latterich M, Silver PA. The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Molecular Biology of the Cell. 12: 3226-41. PMID 11598205  1
2001 Tham WH, Wyithe JS, Ko Ferrigno P, Silver PA, Zakian VA. Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions. Molecular Cell. 8: 189-99. PMID 11511372 DOI: 10.1016/S1097-2765(01)00287-8  1
2001 McBride AE, Silver PA. State of the arg: protein methylation at arginine comes of age. Cell. 106: 5-8. PMID 11461695 DOI: 10.1016/S0092-8674(01)00423-8  1
2001 Lei EP, Krebber H, Silver PA. Messenger RNAs are recruited for nuclear export during transcription. Genes & Development. 15: 1771-82. PMID 11459827 DOI: 10.1101/gad.892401  1
2001 Hood JK, Hwang WW, Silver PA. The Saccharomyces cerevisiae cyclin Clb2p is targeted to multiple subcellular locations by cis- and trans-acting determinants. Journal of Cell Science. 114: 589-97. PMID 11171327  1
2000 Brodsky AS, Silver PA. Pre-mRNA processing factors are required for nuclear export Rna. 6: 1737-1749. PMID 11142374 DOI: 10.1017/S1355838200001059  1
2000 Colas P, Cohen B, Ferrigno PK, Silver PA, Brent R. Targeted modification and transportation of cellular proteins Proceedings of the National Academy of Sciences of the United States of America. 97: 13720-13725. PMID 11106396 DOI: 10.1073/pnas.97.25.13720  1
2000 Weiss VH, McBride AE, Soriano MA, Filman DJ, Silver PA, Hogle JM. The structure and oligomerization of the yeast arginine methyltransferase, Hmt1. Nature Structural Biology. 7: 1165-71. PMID 11101900 DOI: 10.1038/82028  1
2000 Stage-Zimmermann T, Schmidt U, Silver PA. Factors affecting nuclear export of the 60S ribosomal subunit in vivo Molecular Biology of the Cell. 11: 3777-3789. PMID 11071906  1
2000 Krebber H, Silver PA. Directing proteins to nucleus by fusion to nuclear localization signal tags Methods in Enzymology. 327: 283-296. PMID 11044991 DOI: 10.1016/S0076-6879(00)27284-4  1
2000 Hood JK, Silver PA. Diverse nuclear transport pathways regulate cell proliferation and oncogenesis Biochimica Et Biophysica Acta - Reviews On Cancer. 1471: M31-M41. PMID 10967423 DOI: 10.1016/S0304-419X(00)00018-4  1
2000 Prinz WA, Grzyb L, Veenhuis M, Kahana JA, Silver PA, Rapoport TA. Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. The Journal of Cell Biology. 150: 461-74. PMID 10931860 DOI: 10.1083/jcb.150.3.461  1
2000 Shen EC, Stage-Zimmermann T, Chui P, Silver PA. 7The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex. The Journal of Biological Chemistry. 275: 23718-24. PMID 10823828 DOI: 10.1074/jbc.M002312200  1
2000 Ferrigno P, Silver PA. Polyglutamine expansions: Proteolysis, chaperones, and the dangers of promiscuity Neuron. 26: 9-12. PMID 10798387  1
2000 Hood JK, Casolari JM, Silver PA. Nup2p is located on the nuclear side of the nuclear pore complex and coordinates Srp1p/importin-alpha export. Journal of Cell Science. 113: 1471-80. PMID 10725229  1
2000 Jones AL, Booth Quimby B, Hood JK, Ferrigno P, Keshava PH, Silver PA, Corbett AH. SAC3 may link nuclear protein export to cell cycle progression Proceedings of the National Academy of Sciences of the United States of America. 97: 3224-3229. PMID 10716708 DOI: 10.1073/pnas.050432997  1
2000 Damelin M, Silver PA. Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex Molecular Cell. 5: 133-140. PMID 10678175  1
2000 McBride AE, Weiss VH, Kim HK, Hogle JM, Silver PA. Analysis of the yeast arginine methyltransferase Hmt1p/Rmt1p and its in vivo function. Cofactor binding and substrate interactions. The Journal of Biological Chemistry. 275: 3128-36. PMID 10652296 DOI: 10.1074/jbc.275.5.3128  1
2000 Guarente L, Silver PA. Nucleus and gene expression: Function following form in the nucleus Current Opinion in Cell Biology. 12: 279. DOI: 10.1016/S0955-0674(00)00088-0  1
1999 Brodsky AS, Silver PA. Nuclear transport HEATs up Nature Cell Biology. 1: E66-E67. PMID 10559913  1
1999 Ferrigno P, Silver PA. Regulated nuclear localization of stress-responsive factors: How the nuclear trafficking of protein kinases and transcription factors contributes to cell survival Oncogene. 18: 6129-6134. PMID 10557104  1
1999 Morehouse H, Buratowski RM, Silver PA, Buratowski S. The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 12542-7. PMID 10535958  1
1999 Moy TI, Silver PA. Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes & Development. 13: 2118-33. PMID 10465789  1
1999 Krebber H, Taura T, Lee MS, Silver PA. Uncoupling of hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export Genes and Development. 13: 1994-2004. PMID 10444597  1
1999 Zeng X, Kahana JA, Silver PA, Morphew MK, McIntosh JR, Fitch IT, Carbon J, Saunders WS. Slk19p is a centromere protein that functions to stabilize mitotic spindles. The Journal of Cell Biology. 146: 415-25. PMID 10427094 DOI: 10.1083/jcb.146.2.415  1
1999 Hood JK, Silver PA. In or out? Regulating nuclear transport Current Opinion in Cell Biology. 11: 241-247. PMID 10209150 DOI: 10.1016/S0955-0674(99)80032-5  1
1999 Ferrigno P, Silver PA. Analysis of nuclear transport in vivo Methods in Cell Biology. 107-122.  1
1998 Ferrigno P, Posas F, Koepp D, Saito H, Silver PA. Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. The Embo Journal. 17: 5606-14. PMID 9755161 DOI: 10.1093/emboj/17.19.5606  1
1998 Koepp DM, Silver PA. Nucleocytoplasmic transport and cell proliferation Biochimica Et Biophysica Acta - Reviews On Cancer. 1377. PMID 9606975 DOI: 10.1016/S0304-419X(97)00036-X  1
1998 Shen EC, Henry MF, Weiss VH, Valentini SR, Silver PA, Lee MS. Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes & Development. 12: 679-91. PMID 9499403  1
1998 Vodicka MA, Koepp DM, Silver PA, Emerman M. HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. Genes & Development. 12: 175-85. PMID 9436978  1
1996 Corbett A, Ferrigno P, Henry M, Kahana J, Koepp D, Lee M, Nguyen L, Schlenstedt G, Seedorf M, Shen E, Taura T, Wong D, Silver P. Genetic analysis of macromolecular transport across the nuclear envelope. Experimental Cell Research. 229: 212-6. PMID 8986600 DOI: 10.1006/excr.1996.0362  1
1996 Koepp DM, Silver PA. A GTPase controlling nuclear trafficking: Running the right way or walking RANdomly? Cell. 87: 1-4. PMID 8858141 DOI: 10.1016/S0092-8674(00)81315-X  1
1996 Koepp DM, Wong DH, Corbett AH, Silver PA. Dynamic localization of the nuclear import receptor and its interactions with transport factors Journal of Cell Biology. 133: 1163-1176. PMID 8682856 DOI: 10.1083/jcb.133.6.1163  1
1995 Corbett AH, Koepp DM, Schlenstedt G, Lee MS, Hopper AK, Silver PA. Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import Journal of Cell Biology. 130: 1017-1026. PMID 7657689 DOI: 10.1083/jcb.130.5.1017  1
1995 Schlenstedt G, Wong DH, Koepp DM, Silver PA. Mutants in a yeast Ran binding protein are defective in nuclear transport Embo Journal. 14: 5367-5378. PMID 7489726  1
1986 Silver PA, Brent R, Ptashne M. DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae. Molecular and Cellular Biology. 6: 4763-6. PMID 3099172  1
1984 Silver PA, Keegan LP, Ptashne M. Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proceedings of the National Academy of Sciences of the United States of America. 81: 5951-5. PMID 6091123  1
1983 Watts C, Goodman JM, Silver P, Wickner W. Analysis of M13 procoat assembly into membranes in vitro. Methods in Enzymology. 97: 130-8. PMID 6361469 DOI: 10.1016/0076-6879(83)97126-4  1
1983 Silver P, Wickner W. Genetic mapping of the Escherichia coli leader (signal) peptidase gene (lep): A new approach for determining the map position of a cloned gene Journal of Bacteriology. 154: 569-572. PMID 6341355  1
1983 Sudate T, Silver P, Wickner W. [4] Molecular genetics of Escherichia coli leader peptidase Methods in Enzymology. 97: 46-57. PMID 6318034 DOI: 10.1016/0076-6879(83)97117-3  1
1982 Wolfe PB, Silver P, Wickner W. The isolation of homogeneous leader peptidase from a strain of Escherichia coli which overproduces the enzyme Journal of Biological Chemistry. 257: 7898-7902. PMID 6282859  1
1981 Watts C, Silver P, Wickner W. Membrane assembly from purified components. II. Assembly of M13 procoat into liposomes reconstituted with purified leader peptidase Cell. 25: 347-353. PMID 7026043 DOI: 10.1016/0092-8674(81)90053-2  1
1981 Silver P, Watts C, Wickner W. Membrane assembly from purified components. I. Isolated M13 procoat does not require ribosomes or soluble proteins for processing by membranes Cell. 25: 341-345. PMID 7026042 DOI: 10.1016/0092-8674(81)90052-0  1
1980 Silver P, Wickner WT. Role of M13 gene 1 protein in filamentous virus assembly Journal of Virology. 35: 256-258. PMID 7411692  1
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