| Year |
Citation |
Score |
| 2016 |
Pal A, Das RS, Zhang W, Lang M, McLaughlin LW, Szostak JW. Effect of terminal 3'-hydroxymethyl modification of an RNA primer on nonenzymatic primer extension. Chemical Communications (Cambridge, England). 52: 11905-11907. PMID 27722518 DOI: 10.1039/C6Cc06925H |
0.768 |
|
| 2014 |
Yu H, Schlegel MK, McLaughlin LW. The synthesis and structural characterization of both diastereomers of 5′-(hydroxymethyl)-6,5′-cyclo-2′,5′-dideoxyuridine cyclonucleosides Rsc Advances. 4: 32588-32593. DOI: 10.1039/C4Ra04784B |
0.588 |
|
| 2013 |
Yueh H, Pal A, Chang K, Schlegel MK, McLaughlin LW. Synthesis and NMR assignment of the two diastereomers of 8,6′-Cyclo-2′,6′-Dideoxyadenosine Nucleosides, Nucleotides and Nucleic Acids. 32: 320-332. PMID 23638925 DOI: 10.1080/15257770.2013.778997 |
0.744 |
|
| 2013 |
Pal A, Salandria KJ, Arico JW, Schlegel MK, McLaughlin LW. 2,3-Dicyclohexylsuccinimide as a directing/protecting group for the regioselective glycosylation or alkylation of purines Chemical Communications. 49: 2936-2938. PMID 23459620 DOI: 10.1039/C3Cc37265K |
0.746 |
|
| 2012 |
Yueh H, Yu H, Theile CS, Pal A, Horhota A, Greco N, Christianson CV, McLaughlin LW. Synthesis and properties of DNA containing cyclonucleosides Nucleosides, Nucleotides and Nucleic Acids. 31: 661-679. PMID 23004930 DOI: 10.1080/15257770.2012.716189 |
0.785 |
|
| 2012 |
Theile CS, McLaughlin LW. An efficient synthetic approach to 6,5′-(S)- and 6,5′-(R)- cyclouridine Chemical Communications. 48: 5587-5589. PMID 22531603 DOI: 10.1039/C2Cc31597A |
0.699 |
|
| 2012 |
Theile CS, McLaughlin LW. Synthesis of 6,6′-(S)-cyclo-2′-deoxyuridine featuring a unique Barbier-style cyclization Rsc Advances. 2: 11678-11680. DOI: 10.1039/C2Ra21559D |
0.741 |
|
| 2012 |
Theile CS, McLaughlin LW. ChemInform Abstract: An Efficient Synthetic Approach to 6,5′-(S)- and 6,5′-(R)-Cyclouridine. Cheminform. 43: no-no. DOI: 10.1002/chin.201239214 |
0.679 |
|
| 2011 |
Akabayov B, Kulczyk AW, Akabayov SR, Theile C, McLaughlin LW, Beauchamp B, van Oijen AM, Richardson CC. Pyrovanadolysis, a pyrophosphorolysis-like reaction mediated by pyrovanadate, Mn2+, and DNA polymerase of bacteriophage T7. The Journal of Biological Chemistry. 286: 29146-57. PMID 21697085 DOI: 10.1074/Jbc.M111.250944 |
0.747 |
|
| 2011 |
Salandria KJ, Arico JW, Calhoun AK, McLaughlin LW. Stability of DNA containing a structural water mimic in an A-T rich sequence Journal of the American Chemical Society. 133: 1766-1768. PMID 21244084 DOI: 10.1021/Ja1103684 |
0.765 |
|
| 2010 |
Arico JW, Calhoun AK, McLaughlin LW. Preparation of the 2′-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation Journal of Organic Chemistry. 75: 1360-1365. PMID 20146451 DOI: 10.1021/Jo902616S |
0.338 |
|
| 2010 |
Arico JW, Calhoun AK, Salandria KJ, McLaughlin LW. Tetramethylsuccinimide as a directing/protecting group in purine glycosylates Organic Letters. 12: 120-122. PMID 19961189 DOI: 10.1021/Ol9025028 |
0.746 |
|
| 2009 |
Chen JJ, Tsai CH, Cai X, Horhota AT, McLaughlin LW, Szostak JW. Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates. Plos One. 4: e4949. PMID 19305495 DOI: 10.1371/Journal.Pone.0004949 |
0.478 |
|
| 2009 |
Chen JJ, Tsai CH, Cai X, Horhota AT, McLaughlin LW, Szostak JW. Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates Plos One. 4. DOI: 10.1371/journal.pone.0004949 |
0.305 |
|
| 2008 |
Chen H, Meena, McLaughlin LW. A Janus-Wedge DNA triplex with A-W1-T and G-W2-C base triplets Journal of the American Chemical Society. 130: 13190-13191. PMID 18783217 DOI: 10.1021/Ja804607V |
0.396 |
|
| 2007 |
Sun Z, McLaughlin LW. Probing the nature of three-centered hydrogen bonds in minor-groove ligand-DNA interactions: The contribution of fluorine hydrogen bonds to complex stability Journal of the American Chemical Society. 129: 12531-12536. PMID 17894492 DOI: 10.1021/Ja073981P |
0.401 |
|
| 2007 |
Sun Z, McLaughlin LW. Effects of the minor groove pyrimidine nucleobase functional groups on the stability of duplex DNA: The impact of uncompensated minor groove amino groups Biopolymers. 87: 183-195. PMID 17657710 DOI: 10.1002/Bip.20817 |
0.401 |
|
| 2007 |
Meena, Sam M, Pierce K, Szostak JW, McLaughlin LW. 2',3'-Dideoxy-3'-thionucleoside triphosphates: syntheses and polymerase substrate activities. Organic Letters. 9: 1161-3. PMID 17319676 DOI: 10.1021/Ol070147W |
0.433 |
|
| 2006 |
Horhota AT, Szostak JW, McLaughlin LW. Glycerol nucleoside triphosphates: Synthesis and polymerase substrate activities Organic Letters. 8: 5345-5347. PMID 17078714 DOI: 10.1021/Ol062232U |
0.348 |
|
| 2006 |
Meena, Sun Z, Mulligan C, McLaughlin LW. Removal of a single minor-groove functional group eliminates A-tract curvature Journal of the American Chemical Society. 128: 11756-11757. PMID 16953605 DOI: 10.1021/Ja0632310 |
0.34 |
|
| 2006 |
Sun Z, Ahmed S, McLaughlin LW. Syntheses of pyridine C-nucleosides as analogues of the natural nucleosides dC and dU Journal of Organic Chemistry. 71: 2922-2925. PMID 16555858 DOI: 10.1021/Jo060066Y |
0.338 |
|
| 2006 |
Joy A, Guler G, Ahmed S, McLaughlin LW, Schuster GB. Polaronic semiconductor behavior of long-range charge transfer in DNA oligomers in solution: controlling barriers to long-distance radical cation migration in DNA with thymine analogs. Faraday Discussions. 131: 357-65; discussion 3. PMID 16512383 DOI: 10.1039/B505550D |
0.374 |
|
| 2006 |
Sun Z, Lo W, McLaughlin LW. 6-Amino-3-(β-D-2-deoxy-erythro-furanosyl)-2-fluoropyridine: A nucleoside analogue Acta Crystallographica Section E: Structure Reports Online. 62: o1437-o1439. DOI: 10.1107/S1600536806007707 |
0.302 |
|
| 2005 |
Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW. High fidelity TNA synthesis by Therminator polymerase. Nucleic Acids Research. 33: 5219-25. PMID 16157867 DOI: 10.1093/Nar/Gki840 |
0.437 |
|
| 2005 |
Horhota A, Zou K, Ichida JK, Yu B, McLaughlin LW, Szostak JW, Chaput JC. Kinetic analysis of an efficient DNA-dependent TNA polymerase. Journal of the American Chemical Society. 127: 7427-34. PMID 15898792 DOI: 10.1021/Ja0428255 |
0.449 |
|
| 2005 |
Zou K, Horhota A, Yu B, Szostak JW, McLaughlin LW. Synthesis of α-L-threofuranosyl nucleoside triphosphates (tNTPs) Organic Letters. 7: 1485-1487. PMID 15816733 DOI: 10.1021/Ol050081+ |
0.339 |
|
| 2005 |
Ichida JK, Zou K, Horhota A, Yu B, McLaughlin LW, Szostak JW. An in vitro selection system for TNA. Journal of the American Chemical Society. 127: 2802-3. PMID 15740086 DOI: 10.1021/Ja045364W |
0.436 |
|
| 2004 |
Stewart KM, Rojo J, McLaughlin LW. Ru(II) tris(bipyridyl) complexes with six oligonucleotide arms as precursors for the generation of supramolecular assemblies Angewandte Chemie - International Edition. 43: 5808-5811. PMID 15523720 DOI: 10.1002/Anie.200460399 |
0.581 |
|
| 2004 |
Sharma SK, McLaughlin LW. Triplex mediated delivery of a platinum complex to a specific DNA target site Journal of Inorganic Biochemistry. 98: 1570-1577. PMID 15458818 DOI: 10.1016/J.Jinorgbio.2004.05.001 |
0.394 |
|
| 2004 |
Stewart KM, McLaughlin LW. Four-Arm Oligonucleotide Ni(II) - Cyclam-Centered Complexes as Precursors for the Generation of Supramolecular Periodic Assemblies Journal of the American Chemical Society. 126: 2050-2057. PMID 14971939 DOI: 10.1021/Ja037424O |
0.647 |
|
| 2004 |
Chen D, Meena, Sharma SK, McLaughlin LW. Formation and Stability of a Janus-Wedge Type of DNA Triplex Journal of the American Chemical Society. 126: 70-71. PMID 14709064 DOI: 10.1021/Ja038081X |
0.492 |
|
| 2003 |
Stewart KM, McLaughlin LW. Design and synthesis of DNA-tethered ruthenium complexes that self-assemble into linear arrays. Chemical Communications (Cambridge, England). 2934-5. PMID 14680248 DOI: 10.1039/B307544C |
0.645 |
|
| 2003 |
Vaish NK, Larralde R, Fraley AW, Szostak JW, McLaughlin LW. A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality Biochemistry. 42: 8842-8851. PMID 12873145 DOI: 10.1021/Bi027354I |
0.776 |
|
| 2003 |
Woods KK, Lan T, McLaughlin LW, Williams LD. The role of minor groove functional groups in DNA hydration. Nucleic Acids Research. 31: 1536-40. PMID 12595562 DOI: 10.1093/Nar/Gkg240 |
0.559 |
|
| 2003 |
Fraley AW, Chen D, Johnson K, McLaughlin LW. An HIV reverse transcriptase-selective nucleoside chain terminator Journal of the American Chemical Society. 125: 616-617. PMID 12526645 DOI: 10.1021/Ja020639Y |
0.789 |
|
| 2002 |
Sun Z, Chen D, Lan T, McLaughlin LW. Importance of minor groove functional groups for the stability of DNA duplexes Biopolymers. 65: 211-217. PMID 12228926 DOI: 10.1002/Bip.10223 |
0.601 |
|
| 2002 |
Sharma SK, McLaughlin LW. Cross-linking of a DNA conjugate tethering a cis-bifunctional platinated complex to a target DNA duplex Journal of the American Chemical Society. 124: 9658-9659. PMID 12175195 DOI: 10.1021/Ja020500N |
0.398 |
|
| 2002 |
Nunes-Düby SE, Radman-Livaja M, Kuimelis RG, Pearline RV, McLaughlin LW, Landy A. λ integrase complementation at the level of DNA binding and complex formation Journal of Bacteriology. 184: 1385-1394. PMID 11844768 DOI: 10.1128/Jb.184.5.1385-1394.2002 |
0.384 |
|
| 2001 |
O'Dea T, McLaughlin LW. Engineering specific cross-links in nucleic acids using glycol linkers. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 5.3. PMID 18428859 DOI: 10.1002/0471142700.Nc0503S00 |
0.396 |
|
| 2001 |
Lan T, McLaughlin LW. Synthesis of a dA-dT base pair analogue and its effects on DNA-ligand binding Bioorganic Chemistry. 29: 198-210. PMID 16256692 DOI: 10.1006/Bioo.2001.1209 |
0.614 |
|
| 2001 |
Gianolio DA, McLaughlin LW. Tethered naphthalene diimide intercalators enhance DNA triplex stability Bioorganic and Medicinal Chemistry. 9: 2329-2334. PMID 11553472 DOI: 10.1016/S0968-0896(01)00135-3 |
0.415 |
|
| 2001 |
Lan T, McLaughlin LW. The energetic contribution of a bifurcated hydrogen bond to the binding of DAPI to dA-dT rich sequences of DNA [4] Journal of the American Chemical Society. 123: 2064-2065. PMID 11456833 DOI: 10.1021/Ja003451S |
0.554 |
|
| 2001 |
Mohanty U, McLaughlin L. On the characteristics of migration of oligomeric DNA in polyacrylamide gels and in free solution Annual Review of Physical Chemistry. 52: 93-106. PMID 11326060 DOI: 10.1146/Annurev.Physchem.52.1.93 |
0.388 |
|
| 2001 |
Lan T, McLaughlin LW. Minor groove functional groups are critical for the B-form conformation of duplex DNA Biochemistry. 40: 968-976. PMID 11170418 DOI: 10.1021/Bi0015212 |
0.585 |
|
| 2000 |
Mohanty U, Searls T, McLaughlin LW. Anomalous Migration of Short Sequences of DNA: Comparison of Theory and Experiment. Journal of Biomolecular Structure & Dynamics. 17: 371-5. PMID 22607446 DOI: 10.1080/07391102.2000.10506643 |
0.383 |
|
| 2000 |
Dong Li Chen, McLaughlin LW. Use of pK(a) differences to enhance the formation of base triplets involving C-G and G-C base pairs Journal of Organic Chemistry. 65: 7468-7474. PMID 11076604 DOI: 10.1021/Jo000754W |
0.313 |
|
| 2000 |
Vaish NK, Fraley AW, Szostak JW, McLaughlin LW. Expanding the structural and functional diversity of RNA: Analog uridine triphosphates as candidates for in vitro selection of nucleic acids Nucleic Acids Research. 28: 3316-3322. PMID 10954600 DOI: 10.1093/Nar/28.17.3316 |
0.769 |
|
| 2000 |
Núñez ME, Noyes KT, Gianolio DA, McLaughlin LW, Barton JK. Long-range guanine oxidation in DNA restriction fragments by a triplex- directed naphthalene diimide intercalator Biochemistry. 39: 6190-6199. PMID 10821694 DOI: 10.1021/Bi000285S |
0.377 |
|
| 2000 |
Gianolio DA, Segismundo JM, McLaughlin LW. Tethered naphthalene diimide-based intercalators for DNA triplex stabilization Nucleic Acids Research. 28: 2128-2134. PMID 10773082 DOI: 10.1093/Nar/28.10.2128 |
0.443 |
|
| 2000 |
Searls T, Li Chen D, Lan T, McLaughlin LW. Nucleoside analogue substitutions in the trinucleotide DNA template recognition sequence 3'-(CTG)-5' and their effects on the activity of bacteriophage T7 primase Biochemistry. 39: 4375-4382. PMID 10757986 DOI: 10.1021/Bi992855Y |
0.62 |
|
| 2000 |
Mohanty U, Searls T, McLaughlin LW. Migration effects for small phosphate-labeled single-stranded DNA fragments in gels: Prediction and experiment [6] Journal of the American Chemical Society. 122: 1225-1226. DOI: 10.1021/Ja992241G |
0.367 |
|
| 2000 |
Lan T, McLaughlin LW. Minor groove hydration is critical to the stability of DNA duplexes [13] Journal of the American Chemical Society. 122: 6512-6513. DOI: 10.1021/Ja000686V |
0.383 |
|
| 2000 |
Vicie DA, Odom DT, Núñez ME, Gianolio DA, McLaughlin LW, Barton JK. Oxidative repair of a thymine dimer in DNA from a distance by a covalently linked organic intercalator Journal of the American Chemical Society. 122: 8603-8611. DOI: 10.1021/Ja000280I |
0.413 |
|
| 2000 |
Bevers S, Schutte S, McLaughlin LW. Naphthalene- and perylene-based linkers for the stabilization of hairpin triplexes Journal of the American Chemical Society. 122: 5905-5915. DOI: 10.1021/Ja0001714 |
0.445 |
|
| 1999 |
Gianolio DA, McLaughlin LW. Synthesis and triplex forming properties of pyrimidine derivative containing extended functionality Nucleosides and Nucleotides. 18: 1751-1769. PMID 10478483 DOI: 10.1080/07328319908044841 |
0.413 |
|
| 1999 |
Bevers S, Ha SB, McLaughlin LW. Critical nature of a specific uridine O2-carbonyl for cleavage by the hammerhead ribozyme Biochemistry. 38: 7710-7718. PMID 10387010 DOI: 10.1021/Bi982977A |
0.32 |
|
| 1999 |
Wiederholt K, McLaughlin LW. A 2, 2′-bipyridine ligand for incorporation into oligodeoxynucleotides: Synthesis, stability and fluorescence properties of ruthenium-DNA complexes Nucleic Acids Research. 27: 2487-2493. PMID 10352178 DOI: 10.1093/Nar/27.12.2487 |
0.375 |
|
| 1999 |
Searls T, McLaughlin LW. Synthesis of the analogue nucleoside 3-deaza-2'-deoxycytidine and its template activity with DNA polymerase Tetrahedron. 55: 11985-11996. DOI: 10.1016/S0040-4020(99)00703-6 |
0.413 |
|
| 1999 |
Smith SA, McLaughlin LW. Probing the interface of the trp repressor-operator complex using operator sequences containing isosteric base-pair analogues Bioorganic Chemistry. 27: 215-226. DOI: 10.1006/Bioo.1998.1129 |
0.362 |
|
| 1998 |
St. Clair A, Xiang G, McLaughlin LW. Synthesis and triplex forming properties of an acyclic N7-glycosylated guanine nucleoside Nucleosides and Nucleotides. 17: 925-937. PMID 9708332 DOI: 10.1080/07328319808003464 |
0.4 |
|
| 1998 |
Guo MJ, Hildbrand S, Leumann CJ, McLaughlin LW, Waring MJ. Inhibition of DNA polymerase reactions by pyrimidine nucleotide analogues lacking the 2-keto group Nucleic Acids Research. 26: 1863-1869. PMID 9518477 DOI: 10.1093/Nar/26.8.1863 |
0.42 |
|
| 1998 |
Wiederholt K, McLaughlin LW. Duplex stabilization by DNA-Hoechst 33258 conjugates: Effects of base pair mismatches Nucleosides and Nucleotides. 17: 1895-1904. DOI: 10.1080/07328319808004728 |
0.406 |
|
| 1998 |
Xiang G, McLaughlin LW. A cytosine analogue containing a conformationally flexible acyclic linker for triplex formation at sites with contiguous G-C base pairs Tetrahedron. 54: 375-392. DOI: 10.1016/S0040-4020(97)10289-7 |
0.34 |
|
| 1997 |
Rajur SB, Robles J, Wiederholt K, Kuimelis RG, McLaughlin LW. Hoechst 33258 Tethered by a Hexa(ethylene glycol) Linker to the 5'-Termini of Oligodeoxynucleotide 15-Mers: Duplex Stabilization and Fluorescence Properties. The Journal of Organic Chemistry. 62: 523-529. PMID 11671444 DOI: 10.1021/Jo9618536 |
0.461 |
|
| 1997 |
Kuimelis RG, McLaughlin LW. Application of a 5/-bridging phosphorothioate to probe divalent metal and hammerhead ribozyme mediated RNA cleavage Bioorganic and Medicinal Chemistry. 5: 1051-1061. PMID 9222498 DOI: 10.1016/S0968-0896(97)00041-2 |
0.364 |
|
| 1997 |
Smith SA, McLaughlin LW. Probing contacts to the DNA backbone in the trp repressor-operator sequence-specific protein-nucleic acid complex using diastereomeric methylphosphonate analogues Biochemistry. 36: 6046-6058. PMID 9166775 DOI: 10.1021/Bi9700781 |
0.376 |
|
| 1997 |
Wiederholt K, Rajur SB, McLaughlin LW. Oligonucleotides tethering Hoechst 33258 derivatives: Effect of the conjugation site on duplex stabilization and fluorescence properties Bioconjugate Chemistry. 8: 119-126. PMID 9095351 DOI: 10.1021/Bc960086E |
0.415 |
|
| 1997 |
Robles J, McLaughlin LW. DNA triplex stabilization using a tethered minor groove binding Hoechst 33258 analogue Journal of the American Chemical Society. 119: 6014-6021. DOI: 10.1021/Ja963694D |
0.415 |
|
| 1996 |
Xiang G, Bogacki R, McLaughlin LW. Use of a pyrimidine nucleoside that functions as a bidentate hydrogen bond donor for the recognition of isolated or contiguous G-C base pairs by oligonucleotide-directed triplex formation. Nucleic Acids Research. 24: 1963-70. PMID 8657581 DOI: 10.1093/Nar/24.10.1963 |
0.423 |
|
| 1996 |
Bevers S, Xiang G, McLaughlin LW. Importance of specific adenosine N3-nitrogens for efficient cleavage by a hammerhead ribozyme. Biochemistry. 35: 6483-90. PMID 8639595 DOI: 10.1021/Bi952868L |
0.311 |
|
| 1996 |
Kuimelis RG, McLaughlin LW. Ribozyme-mediated cleavage of a substrate analogue containing an internucleotide-bridging 5'-phosphorothioate: evidence for the single-metal model. Biochemistry. 35: 5308-17. PMID 8611518 DOI: 10.1021/Bi952994P |
0.311 |
|
| 1996 |
Wiederholt K, Rajur SB, Giuliano J, O'Donnell MJ, McLaughlin LW. DNA-tethered Hoechst groove-binding agents: Duplex stabilization and fluorescence characteristics Journal of the American Chemical Society. 118: 7055-7062. DOI: 10.1021/Ja960948M |
0.415 |
|
| 1996 |
Robles J, Rajur SB, McLaughlin LW. A parallel-stranded DNA triplex tethering a Hoechst 33258 analogue results in complex stabilization by simultaneous major groove and minor groove binding Journal of the American Chemical Society. 118: 5820-5821. DOI: 10.1021/Ja9608914 |
0.403 |
|
| 1995 |
Kuimelis RG, McLaughlin LW. Cleavage properties of an oligonucleotide containing a bridged internucleotide 5'-phosphorothioate RNA linkage. Nucleic Acids Research. 23: 4753-60. PMID 8532515 DOI: 10.1093/Nar/23.23.4753 |
0.345 |
|
| 1995 |
Mendelman LV, Kuimelis RG, McLaughlin LW, Richardson CC. Effects of base analog substitutions in the noncoding dC of the 3'-d(CTG)-5' template recognition site of the bacteriophage T7 primase. Biochemistry. 34: 10187-93. PMID 7640273 DOI: 10.1021/Bi00032A012 |
0.408 |
|
| 1995 |
O'Donnell MJ, Rajur SB, McLaughlin LW. Synthesis and properties of a Hoechst-like minor-groove binding agent tethered to an oligodeoxynucleotide. Bioorganic & Medicinal Chemistry. 3: 743-50. PMID 7582952 DOI: 10.1016/0968-0896(95)00055-L |
0.401 |
|
| 1994 |
Fidanza JA, Ozaki H, McLaughlin LW. Functionalization of oligonucleotides by the incorporation of thio-specific reporter groups. Methods in Molecular Biology (Clifton, N.J.). 26: 121-43. PMID 8313000 DOI: 10.1007/978-1-59259-513-6_4 |
0.305 |
|
| 1994 |
Smith SA, Rajur SB, McLaughlin LW. Specific purine N7-nitrogens are critical for high affinity binding by the trp repressor. Nature Structural Biology. 1: 18-22. PMID 7656001 DOI: 10.1038/Nsb0194-18 |
0.318 |
|
| 1994 |
Fu DJ, Rajur SB, McLaughlin LW. Activity of the hammerhead ribozyme upon inversion of the stereocenters for the guanosine 2'-hydroxyls. Biochemistry. 33: 13903-9. PMID 7524667 DOI: 10.1021/Bi00250A045 |
0.344 |
|
| 1994 |
O'Donnel MJ, Herbert N, McLaughlin LW. The stereospecific introduction of reporter groups to oligodeoxynucleotides by the labeling of individual phosphorus diastereomers Bioorganic and Medicinal Chemistry Letters. 4: 1001-1004. DOI: 10.1016/S0960-894X(01)80670-3 |
0.304 |
|
| 1994 |
Limauro S, Benseler F, McLaughlin LW. 1-Methylguanosine substitutions of the conserved guanosine residues inactive the hammerhead ribozyme Bioorganic and Medicinal Chemistry Letters. 4: 2189-2192. DOI: 10.1016/S0960-894X(00)80069-4 |
0.313 |
|
| 1993 |
Fu DJ, Rajur SB, McLaughlin LW. Importance of specific guanosine N7-nitrogens and purine amino groups for efficient cleavage by a hammerhead ribozyme. Biochemistry. 32: 10629-37. PMID 8399208 DOI: 10.1021/Bi00091A013 |
0.308 |
|
| 1993 |
Rink SM, Solomon MS, Taylor MJ, Rajur SB, McLaughlin LW, Hopkins PB. Covalent structure of a nitrogen mustard-induced DNA interstrand cross-link: An N7-to-N7 linkage of deoxyguanosine residues at the duplex sequence 5'-d(GNC) Journal of the American Chemical Society. 115: 2551-2557. DOI: 10.1021/Ja00060A001 |
0.393 |
|
| 1992 |
Mazzarelli JM, Rajur SB, Iadarola PL, McLaughlin LW. Interactions between the trp repressor and its operator sequence as studied by base analogue substitution. Biochemistry. 31: 5925-36. PMID 1610835 DOI: 10.1021/Bi00140A032 |
0.369 |
|
| 1992 |
Diekmann S, Mazzarelli JM, McLaughlin LW, von Kitzing E, Travers AA. DNA curvature does not require bifurcated hydrogen bonds or pyrimidine methyl groups. Journal of Molecular Biology. 225: 729-38. PMID 1602479 DOI: 10.1016/0022-2836(92)90397-3 |
0.408 |
|
| 1992 |
Hall KB, McLaughlin LW. Properties of pseudouridine N1 imino protons located in the major groove of an A-form RNA duplex. Nucleic Acids Research. 20: 1883-9. PMID 1579489 DOI: 10.1093/Nar/20.8.1883 |
0.331 |
|
| 1992 |
Ozaki H, McLaughlin LW. The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transfer. Nucleic Acids Research. 20: 5205-14. PMID 1408835 DOI: 10.1093/Nar/20.19.5205 |
0.397 |
|
| 1992 |
Patel N, Berglund H, Nilsson L, Rigler R, McLaughlin LW, Gräslund A. Thermodynamics of interaction of a fluorescent DNA oligomer with the anti-tumour drug netropsin. European Journal of Biochemistry / Febs. 203: 361-6. PMID 1310467 DOI: 10.1111/J.1432-1033.1992.Tb16558.X |
0.336 |
|
| 1992 |
Fidanza JA, McLaughlin LW. Use of a thiol tether for the site-specific attachment of reporter groups to DNA Journal of Organic Chemistry. 57: 2340-2346. DOI: 10.1021/Jo00034A028 |
0.436 |
|
| 1992 |
Fidanza JA, Ozaki H, McLaughlin LW. Site-specific labeling of DNA sequences containing phosphorothioate diesters Journal of the American Chemical Society. 114: 5509-5517. DOI: 10.1021/Ja00040A004 |
0.364 |
|
| 1992 |
Rajur SB, McLaughlin LW. The synthesis of oligodeoxynucleotides containing 2-thiothymine and 5-methyl-4-pyrimidinone base analogues Tetrahedron Letters. 33: 6081-6084. DOI: 10.1016/S0040-4039(00)60011-4 |
0.343 |
|
| 1991 |
Hall KB, McLaughlin LW. Properties of a U1/mRNA 5' splice site duplex containing pseudouridine as measured by thermodynamic and NMR methods. Biochemistry. 30: 1795-801. PMID 1993194 DOI: 10.1021/Bi00221A010 |
0.363 |
|
| 1991 |
Hall KB, McLaughlin LW. Thermodynamic and structural properties of pentamer DNA.DNA, RNA.RNA, and DNA.RNA duplexes of identical sequence. Biochemistry. 30: 10606-13. PMID 1931983 DOI: 10.1021/Bi00108A002 |
0.424 |
|
| 1991 |
Aiken CR, McLaughlin LW, Gumport RI. The highly homologous isoschizomers RsrI endonuclease and EcoRI endonuclease do not recognize their target sequence identically. The Journal of Biological Chemistry. 266: 19070-8. PMID 1918026 |
0.312 |
|
| 1991 |
Conway NE, McLaughlin LW. The covalent attachment of multiple fluorophores to DNA containing phosphorothioate diesters results in highly sensitive detection of single-stranded DNA. Bioconjugate Chemistry. 2: 452-7. PMID 1805943 DOI: 10.1021/Bc00012A013 |
0.412 |
|
| 1991 |
Patel N, Graslund A, Berglund H, Nilsson L, Rigler R, McLaughlin LW. Interaction of a minor groove binder with a fluorescent DNA oligomer containing the Eco RI recognition sequence Nucleosides and Nucleotides. 10: 547-548. DOI: 10.1080/07328319108046523 |
0.316 |
|
| 1990 |
Boger DL, Invergo BJ, Coleman RS, Zarrinmayeh H, Kitos PA, Thompson SC, Leong T, McLaughlin LW. A demonstration of the intrinsic importance of stabilizing hydrophobic binding and non-covalent van der Waals contacts dominant in the non-covalent CC-1065/B-DNA binding. Chemico-Biological Interactions. 73: 29-52. PMID 2406033 DOI: 10.1016/0009-2797(90)90107-X |
0.377 |
|
| 1990 |
Wu PG, Nordlund TM, Gildea B, McLaughlin LW. Base stacking and unstacking as determined from a DNA decamer containing a fluorescent base. Biochemistry. 29: 6508-14. PMID 2207092 DOI: 10.1021/Bi00479A024 |
0.314 |
|
| 1990 |
Onway NE, Fidanza JA, McLaughlin LW. Reaction of Internucleotidic Phosphorothioate Diesters with Fluorescent Reporter groups Phosphorus, Sulfur, and Silicon and the Related Elements. 51: 27-30. DOI: 10.1080/10426509008040674 |
0.372 |
|
| 1990 |
Casale R, McLaughlin LW. Synthesis and properties of an oligodeoxynucleotide containing a polycyclic aromatic hydrocarbon site specifically bound to the N2 amino group of a 2'-deoxyguanosine residue Journal of the American Chemical Society. 112: 5264-5271. DOI: 10.1021/Ja00169A039 |
0.373 |
|
| 1990 |
Bischoff R, McLaughlin LW. Chapter 2 HPLC of Transfer RNAS Using Ionic-Hydrophobic Mixed-Mode Chromatography and Hydrophobic-Interaction Chromatography Journal of Chromatography Library. 45: A73-A102. DOI: 10.1016/S0301-4770(08)61468-2 |
0.546 |
|
| 1990 |
Iocono JA, Gildea B, McLaughlin LW. Mild acid hydrolysis of 2-pyrimidinone-containing DNA fragments generates apurinic/apyrimidinic sites Tetrahedron Letters. 31: 175-178. DOI: 10.1016/S0040-4039(00)94363-6 |
0.42 |
|
| 1989 |
Hodges RR, Conway NE, McLaughlin LW. "Post-assay" covalent labeling of phosphorothioate-containing nucleic acids with multiple fluorescent markers. Biochemistry. 28: 261-7. PMID 2706249 DOI: 10.1021/Bi00427A036 |
0.334 |
|
| 1989 |
Gildea B, McLaughlin LW. The synthesis of 2-pyrimidinone nucleosides and their incorporation into oligodeoxynucleotides. Nucleic Acids Research. 17: 2261-81. PMID 2704620 DOI: 10.1093/Nar/17.6.2261 |
0.344 |
|
| 1989 |
Fidanza JA, McLaughlin LW. Introduction of reporter groups at specific sites in DNA containing phosphorothioate diesters Journal of the American Chemical Society. 111: 9117-9119. DOI: 10.1021/Ja00207A028 |
0.407 |
|
| 1988 |
Diekmann S, von Kitzing E, McLaughlin L, Ott J, Eckstein F. The influence of exocyclic substituents of purine bases on DNA curvature. Proceedings of the National Academy of Sciences of the United States of America. 84: 8257-61. PMID 3479789 DOI: 10.1073/Pnas.84.23.8257 |
0.38 |
|
| 1988 |
Blanks R, McLaughlin LW. An oligodeoxynucleotide affinity column for the isolation of sequence specific DNA binding proteins. Nucleic Acids Research. 16: 10283-99. PMID 3194200 DOI: 10.1093/Nar/16.21.10283 |
0.412 |
|
| 1988 |
Diekmann S, McLaughlin LW. DNA curvature in native and modified EcoRI recognition sites and possible influence upon the endonuclease cleavage reaction. Journal of Molecular Biology. 202: 823-34. PMID 3172240 DOI: 10.1016/0022-2836(88)90561-X |
0.456 |
|
| 1988 |
McLaughlin LW, Leong T, Benseler F, Piel N. A new approach to the synthesis of a protected 2-aminopurine derivative and its incorporation into oligodeoxynucleotides containing the Eco RI and Bam HI recognition sites. Nucleic Acids Research. 16: 5631-44. PMID 2838824 DOI: 10.1093/Nar/16.12.5631 |
0.373 |
|
| 1987 |
Hoffmann PU, McLaughlin LW. Synthesis and reactivity of intermediates formed in the T4 RNA ligase reaction. Nucleic Acids Research. 15: 5289-303. PMID 3299268 DOI: 10.1093/Nar/15.13.5289 |
0.373 |
|
| 1987 |
McLaughlin LW, Benseler F, Graeser E, Piel N, Scholtissek S. Effects of functional group changes in the EcoRI recognition site on the cleavage reaction catalyzed by the endonuclease. Biochemistry. 26: 7238-45. PMID 2827747 DOI: 10.1021/Bi00397A007 |
0.359 |
|
| 1987 |
Lycksell PO, Gräslund A, Claesens F, McLaughlin LW, Larsson U, Rigler R. Base pair opening dynamics of a 2-aminopurine substituted Eco RI restriction sequence and its unsubstituted counterpart in oligonucleotides. Nucleic Acids Research. 15: 9011-25. PMID 2825124 DOI: 10.1093/Nar/15.21.9011 |
0.323 |
|
| 1987 |
McLaughlin LW, Bischoff R. Resolution of RNA using high-performance liquid chromatography. Journal of Chromatography. 418: 51-72. PMID 2442185 DOI: 10.1016/0378-4347(87)80004-X |
0.536 |
|
| 1985 |
McLaughlin LW, Piel N, Graeser E. Donor activation in the T4 RNA ligase reaction. Biochemistry. 24: 267-73. PMID 3978074 DOI: 10.1021/Bi00323A005 |
0.336 |
|
| 1985 |
Bischoff R, McLaughlin LW. Isolation of specific tRNAs using an ionic-hydrophobic mixed-mode chromatographic matrix. Analytical Biochemistry. 151: 526-33. PMID 3913336 DOI: 10.1016/0003-2697(85)90215-5 |
0.52 |
|
| 1985 |
Clore GM, Gronenborn AM, McLaughlin LW. The structure of the double-stranded RNA pentamer 5'(CACAG) . 5'(CUGUG) determined by nuclear Overhauser enhancement measurements: interproton distance determination and structure refinement on the basis of X-ray coordinates. European Journal of Biochemistry / Febs. 151: 153-65. PMID 2992954 DOI: 10.1111/J.1432-1033.1985.Tb09080.X |
0.365 |
|
| 1985 |
Mclaughlin LW, Piel N, Hellmann T. Preparation of Protected Ribonucleosides Suitable for Chemical Oligoribonucleotide Synthesis Synthesis. 1985: 322-323. DOI: 10.1055/S-1985-31198 |
0.321 |
|
| 1985 |
Piel N, Benseler F, Graeser E, McLaughlin LW. Synthesis of the oligodeoxyribonucleotide, d(CpTpGpGpApTpCpCpApG), and its substrate activity with the restriction endonuclease, BamHI Bioorganic Chemistry. 13: 323-334. DOI: 10.1016/0045-2068(85)90032-X |
0.402 |
|
| 1984 |
Bischoff R, McLaughlin LW. Mixed-mode chromatographic matrices for the resolution of transfer ribonucleic acids. Journal of Chromatography. 317: 251-61. PMID 6570484 DOI: 10.1016/S0021-9673(01)91664-4 |
0.519 |
|
| 1984 |
Dabkowski W, Skrzypczynski Z, Michalski J, Piel N, McLaughlin LW, Cramer F. Synthesis and reactions of a nucleoside derivative of phosphoric sulfonic anhydride. Studies related to the mechanisms of coupling reactions in the chemical synthesis of oligodeoxyribonucleotides by phosphotriester procedures. Nucleic Acids Research. 12: 9123-35. PMID 6549065 DOI: 10.1093/Nar/12.23.9123 |
0.347 |
|
| 1984 |
Gronenborn AM, Clore GM, McLaughlin LW, Graeser E, Lorber B, Giegé R. Yeast tRNAAsp: codon and wobble codon-anticodon interactions. A transferred nuclear Overhauser enhancement study. European Journal of Biochemistry / Febs. 145: 359-64. PMID 6389132 DOI: 10.1111/J.1432-1033.1984.Tb08562.X |
0.354 |
|
| 1984 |
Wang GH, McLaughlin LW, Sternbach H, Cramer F. Preparation of oligonucleotides corresponding to the acceptor stem of yeast tRNAPhe and their interaction with yeast ATP(CTP):tRNA nucleotidyltransferase. Nucleic Acids Research. 12: 6909-22. PMID 6384932 DOI: 10.1093/Nar/12.17.6909 |
0.351 |
|
| 1984 |
Clore GM, Gronenborn AM, McLaughlin LW. Structure of the ribotrinucleoside diphosphate codon UpUpC bound to tRNAPhe from yeast. A time-dependent transferred nuclear Overhauser enhancement study. Journal of Molecular Biology. 174: 163-73. PMID 6371248 DOI: 10.1016/0022-2836(84)90370-X |
0.338 |
|
| 1984 |
Cosstick R, McLaughlin LW, Eckstein F. Fluorescent labelling of tRNA and oligodeoxynucleotides using T4 RNA ligase. Nucleic Acids Research. 12: 1791-810. PMID 6366740 DOI: 10.1093/Nar/12.4.1791 |
0.397 |
|
| 1984 |
Marugg JE, Piel N, McLaughlin LW, Tromp M, Veeneman GH, van der Marel GA, van Boom JH. Polymer supported DNA synthesis using hydroxybenzotriazole activated phosphotriester intermediates. Nucleic Acids Research. 12: 8639-51. PMID 6095205 DOI: 10.1093/Nar/12.22.8639 |
0.442 |
|
| 1984 |
Clore GM, Gronenborn AM, Piper EA, McLaughlin LW, Graeser E, van Boom JH. The solution structure of a RNA pentadecamer comprising the anticodon loop and stem of yeast tRNAPhe. A 500 MHz 1H-n.m.r. study. The Biochemical Journal. 221: 737-51. PMID 6089745 DOI: 10.1042/Bj2210737 |
0.319 |
|
| 1984 |
Bischoff R, McLaughlin LW. Nucleic acid resolution by mixed-mode chromatography Journal of Chromatography A. 296: 329-337. DOI: 10.1016/S0021-9673(01)96427-1 |
0.527 |
|
| 1983 |
Bischoff R, Graeser E, McLaughlin LW. tRNA separation by high-performance liquid chromatography using an aggregate of ODS-Hypersil and trioctylmethylammonium chloride. Journal of Chromatography. 257: 305-15. PMID 6304129 DOI: 10.1016/S0021-9673(01)88186-3 |
0.517 |
|
| 1983 |
Bischoff R, McLaughlin LW. Chemically synthesized hydrophobic anion-exchange high-performance liquid chromatography supports used for oligonucleotide resolution by mixed mode chromatography Journal of Chromatography A. 270: 117-126. DOI: 10.1016/S0021-9673(01)96356-3 |
0.534 |
|
| 1982 |
McLaughlin LW, Romaniuk E. The use of high-performance liquid chromatography in the isolation and analysis of oligoribonucleotides synthesized by the T4 RNA ligase reaction. Analytical Biochemistry. 124: 37-44. PMID 7125226 DOI: 10.1016/0003-2697(82)90216-0 |
0.382 |
|
| 1982 |
Romaniuk E, McLaughlin LW, Neilson T, Romaniuk PJ. The effect of acceptor oligoribonucleotide sequence on the T4 RNA ligase reaction. European Journal of Biochemistry / Febs. 125: 639-43. PMID 7117259 DOI: 10.1111/J.1432-1033.1982.Tb06730.X |
0.373 |
|
| 1982 |
McLaughlin LW, Graeser E. Enzymatic Synthesis of an RNA Fragment Corresponding to the Anti-Codon Loop and Stem of tRNAPhefrom Yeast Journal of Liquid Chromatography. 5: 2061-2077. DOI: 10.1080/01483918208067617 |
0.371 |
|
| 1981 |
Piechulla B, Hahn U, McLaughlin LW, Küntzel H. Nucleotide sequence of 5S ribosomal RNA from Aspergillus nidulans and Neurospora crassa. Nucleic Acids Research. 9: 1445-50. PMID 6453331 DOI: 10.1093/Nar/9.6.1445 |
0.338 |
|
| 1981 |
McLaughlin LW, Cramer F, Sprinzl M. Rapid analysis of modified tRNAphe from yeast by high-performance liquid chromatography: chromatography of oligonucleotides after RNase T1 digestion on aminopropylsilica and assignment of the fragments based on nucleoside analysis by chromatography on C18-silica. Analytical Biochemistry. 112: 60-9. PMID 6266277 DOI: 10.1016/0003-2697(81)90260-8 |
0.33 |
|
| 1980 |
Lown JW, Joshua AV, McLaughlin LW. Noval antitumor nitrosoureas and related compounds and their reactions with DNA. Journal of Medicinal Chemistry. 23: 798-805. PMID 7401107 |
0.464 |
|
| 1979 |
Lown JW, McLaughlin LW. Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Nature of the chemical reactions with deoxyribonucleic acid. Biochemical Pharmacology. 28: 2123-8. PMID 496996 DOI: 10.1016/0006-2952(79)90193-X |
0.528 |
|
| 1979 |
Lown JW, McLaughlin LW. Nitrosourea-induced DNA single-strand breaks. Biochemical Pharmacology. 28: 1631-8. PMID 383080 DOI: 10.1016/0006-2952(79)90176-X |
0.499 |
|
| 1979 |
Lown JW, McLaughlin LW, Plambeck JA. Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Nature of the intermediates from nitrosourea decomposition. Biochemical Pharmacology. 28: 2115-21. PMID 40555 DOI: 10.1016/0006-2952(79)90192-8 |
0.379 |
|
| 1978 |
Lown J, McLaughlin LW, Chang Y. Mechanism of action of 2-haloethylnitrosoureas on DNA and its relation to their antileukemic properties Bioorganic Chemistry. 7: 97-110. DOI: 10.1016/0045-2068(78)90021-4 |
0.506 |
|
| 1976 |
AKHTAR MH, BEGLEITER A, JOHNSON D, LOWN JW, MCLAUGHLIN L, SIM S. ChemInform Abstract: ANTITUMOR ANTIBIOTICS. VI. CORRELATION OF COVALENT CROSS-LINKING OF DNA BY BIFUNCTIONAL AZIRIDINOQUINONES WITH THEIR ANTINEOPLASTIC ACTIVITY Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197612204 |
0.528 |
|
| 1975 |
Akhtar MH, Begleiter A, Johnson D, Lown JW, McLaughlin L, Sim S. Studies Related to Antitumor Antibiotics. Part VI. Correlation of Covalent Cross-linking of DNA by Bifunctional Aziridinoquinones with their Antineoplastic Activity Canadian Journal of Chemistry. 53: 2891-2905. DOI: 10.1139/V75-409 |
0.506 |
|
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