Year |
Citation |
Score |
2017 |
Huang SC, Wei PC, Hwang-Verslues WW, Kuo WH, Jeng YM, Hu CM, Shew JY, Huang CS, Chang KJ, Lee EY, Lee WH. TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB. Embo Molecular Medicine. PMID 28993429 DOI: 10.15252/Emmm.201606914 |
0.378 |
|
2016 |
Chen JY, Tsai WS, Shao HJ, Wu JC, Lai JM, Lu SH, Hung TF, Yang CT, Wu LC, Chen JS, Lee WH, Chang YC. Sensitive and Specific Biomimetic Lipid Coated Microfluidics to Isolate Viable Circulating Tumor Cells and Microemboli for Cancer Detection. Plos One. 11: e0149633. PMID 26938471 DOI: 10.1371/Journal.Pone.0149633 |
0.34 |
|
2016 |
Kao SH, Wu KJ, Lee WH. Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes. Journal of Clinical Medicine. 5. PMID 26861406 DOI: 10.3390/Jcm5020024 |
0.334 |
|
2015 |
Lee WH, Wu HH, Huang CK. Targeting interleukin-17 receptors. Oncotarget. 6: 18244-5. PMID 26285835 DOI: 10.18632/Oncotarget.4892 |
0.312 |
|
2015 |
Zhu J, Chen H, Guo XE, Qiu XL, Hu CM, Chamberlin AR, Lee WH. Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors. European Journal of Medicinal Chemistry. 96: 196-208. PMID 25874343 DOI: 10.1016/J.Ejmech.2015.04.021 |
0.609 |
|
2015 |
Wu HH, Hwang-Verslues WW, Lee WH, Huang CK, Wei PC, Chen CL, Shew JY, Lee EY, Jeng YM, Tien YW, Ma C, Lee WH. Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines. The Journal of Experimental Medicine. 212: 333-49. PMID 25732306 DOI: 10.1084/Jem.20141702 |
0.301 |
|
2015 |
Hu CM, Zhu J, Guo XE, Chen W, Qiu XL, Ngo B, Chien R, Wang YV, Tsai CY, Wu G, Kim Y, Lopez R, Chamberlin AR, Lee EY, Lee WH. Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism. Oncogene. 34: 1220-30. PMID 24662830 DOI: 10.1038/onc.2014.67 |
0.788 |
|
2014 |
Wang DD, Guo XE, Modrek AS, Chen CF, Chen PL, Lee WH. Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes. The Journal of Biological Chemistry. 289: 16727-35. PMID 24770417 DOI: 10.1074/Jbc.M113.536540 |
0.585 |
|
2014 |
Guo XE, Ngo B, Modrek AS, Lee WH. Targeting tumor suppressor networks for cancer therapeutics. Current Drug Targets. 15: 2-16. PMID 24387338 DOI: 10.2174/1389450114666140106095151 |
0.762 |
|
2013 |
Ngo B, Hu CM, Guo XE, Ngo B, Wei R, Zhu J, Lee WH. Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression. The Journal of Biological Chemistry. 288: 34403-13. PMID 24129578 DOI: 10.1074/jbc.M113.490524 |
0.742 |
|
2013 |
Hwang-Verslues WW, Chang PH, Jeng YM, Kuo WH, Chiang PH, Chang YC, Hsieh TH, Su FY, Lin LC, Abbondante S, Yang CY, Hsu HM, Yu JC, Chang KJ, Shew JY, ... ... Lee WH, et al. Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy. Proceedings of the National Academy of Sciences of the United States of America. 110: 12331-6. PMID 23836662 DOI: 10.1073/Pnas.1222684110 |
0.39 |
|
2013 |
Chen PL, Chen CF, Chen Y, Guo XE, Huang CK, Shew JY, Reddick RL, Wallace DC, Lee WH. Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan. Oncogene. 32: 1193-201. PMID 22562243 DOI: 10.1038/Onc.2012.120 |
0.592 |
|
2013 |
Wang W, Lin L, Li C, Yang W, Wang DD, Chang W, Lee W, Wang J. Abstract 4926: Loss of ZBRK1 contributes to the increase of KAP1 and promotes KAP1-mediated metastasis and invasion in cervical cancer. Cancer Research. 73: 4926-4926. DOI: 10.1158/1538-7445.Am2013-4926 |
0.386 |
|
2012 |
Hwang-Verslues WW, Lee WH, Lee EY. Biomarkers to Target Heterogeneous Breast Cancer Stem Cells. Journal of Molecular Biomarkers & Diagnosis. 6. PMID 24977105 DOI: 10.4172/2155-9929.S8-006 |
0.366 |
|
2012 |
Chang PH, Hwang-Verslues WW, Chang YC, Chen CC, Hsiao M, Jeng YM, Chang KJ, Lee EY, Shew JY, Lee WH. Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway. Cancer Research. 72: 4652-61. PMID 22826604 DOI: 10.1158/0008-5472.Can-12-0877 |
0.413 |
|
2012 |
Tyan SW, Hsu CH, Peng KL, Chen CC, Kuo WH, Lee EY, Shew JY, Chang KJ, Juan LJ, Lee WH. Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change. Plos One. 7: e35128. PMID 22514714 DOI: 10.1371/Journal.Pone.0035128 |
0.391 |
|
2011 |
Guo XE, Chen CF, Wang DD, Modrek AS, Phan VH, Lee WH, Chen PL. Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation. The Journal of Biological Chemistry. 286: 38783-94. PMID 21911497 DOI: 10.1074/Jbc.M111.257956 |
0.589 |
|
2011 |
Wei R, Ngo B, Wu G, Lee WH. Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint. Molecular Biology of the Cell. 22: 3584-94. PMID 21832156 DOI: 10.1091/Mbc.E11-01-0012 |
0.756 |
|
2011 |
Tsai CY, Ngo B, Tapadia A, Hsu PH, Wu G, Lee WH. Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly. The Journal of Biological Chemistry. 286: 30097-106. PMID 21705324 DOI: 10.1074/Jbc.M111.266767 |
0.744 |
|
2011 |
Furuta S, Jeng YM, Zhou L, Huang L, Kuhn I, Bissell MJ, Lee WH. IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells. Science Translational Medicine. 3: 78ra31. PMID 21490275 DOI: 10.1126/Scitranslmed.3001374 |
0.698 |
|
2011 |
Tyan SW, Kuo WH, Huang CK, Pan CC, Shew JY, Chang KJ, Lee EY, Lee WH. Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis. Plos One. 6: e15313. PMID 21249190 DOI: 10.1371/Journal.Pone.0015313 |
0.383 |
|
2010 |
Ahmed KM, Tsai CY, Lee WH. Derepression of HMGA2 via removal of ZBRK1/BRCA1/CtIP complex enhances mammary tumorigenesis. The Journal of Biological Chemistry. 285: 4464-71. PMID 20007691 DOI: 10.1074/Jbc.M109.062265 |
0.456 |
|
2009 |
Hwang-Verslues WW, Kuo WH, Chang PH, Pan CC, Wang HH, Tsai ST, Jeng YM, Shew JY, Kung JT, Chen CH, Lee EY, Chang KJ, Lee WH. Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers. Plos One. 4: e8377. PMID 20027313 DOI: 10.1371/Journal.Pone.0008377 |
0.366 |
|
2009 |
Wu G, Wei R, Cheng E, Ngo B, Lee WH. Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1. Molecular Biology of the Cell. 20: 4686-95. PMID 19776357 DOI: 10.1091/Mbc.E08-11-1123 |
0.767 |
|
2009 |
Wang DD, Shu Z, Lieser SA, Chen PL, Lee WH. Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality. The Journal of Biological Chemistry. 284: 20812-21. PMID 19509288 DOI: 10.1074/Jbc.M109.009605 |
0.322 |
|
2009 |
Qiu XL, Li G, Wu G, Zhu J, Zhou L, Chen PL, Chamberlin AR, Lee WH. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. Journal of Medicinal Chemistry. 52: 1757-67. PMID 19243176 DOI: 10.1021/Jm8015969 |
0.377 |
|
2008 |
Hwang-Verslues WW, Chang KJ, Lee EY, Lee WH. Breast cancer stem cells and tumor suppressor genes. Journal of the Formosan Medical Association = Taiwan Yi Zhi. 107: 751-66. PMID 18926942 DOI: 10.1016/S0929-6646(08)60188-6 |
0.353 |
|
2008 |
Wu G, Qiu XL, Zhou L, Zhu J, Chamberlin R, Lau J, Chen PL, Lee WH. Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. Cancer Research. 68: 8393-9. PMID 18922912 DOI: 10.1158/0008-5472.Can-08-1915 |
0.446 |
|
2008 |
Khidr L, Wu G, Davila A, Procaccio V, Wallace D, Lee WH. Role of SUV3 helicase in maintaining mitochondrial homeostasis in human cells. The Journal of Biological Chemistry. 283: 27064-73. PMID 18678873 DOI: 10.1074/Jbc.M802991200 |
0.748 |
|
2008 |
Wu G, Lin YT, Wei R, Chen Y, Shan Z, Lee WH. Hice1, a novel microtubule-associated protein required for maintenance of spindle integrity and chromosomal stability in human cells. Molecular and Cellular Biology. 28: 3652-62. PMID 18362163 DOI: 10.1128/Mcb.01923-07 |
0.739 |
|
2007 |
Lin X, Liu CC, Gao Q, Zhang X, Wu G, Lee WH. RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survival. Molecular and Cellular Biology. 27: 4905-16. PMID 17470549 DOI: 10.1128/Mcb.02396-06 |
0.432 |
|
2007 |
Jeng YM, Cai-Ng S, Li A, Furuta S, Chew H, Chen PL, Lee EY, Lee WH. Brca1 heterozygous mice have shortened life span and are prone to ovarian tumorigenesis with haploinsufficiency upon ionizing irradiation. Oncogene. 26: 6160-6. PMID 17420720 DOI: 10.1038/Sj.Onc.1210451 |
0.707 |
|
2007 |
Zhou L, Zhu J, Konig H, Lin X, Bhatia R, Chamberlin AR, Chen P, Lee W. Small Molecules Targeting Rad51 Recombinase Synergize with Imatinib and Overcome Imatinib-Resistance in CML. Blood. 110: 466-466. DOI: 10.1182/Blood.V110.11.466.466 |
0.343 |
|
2006 |
Poole AJ, Li Y, Kim Y, Lin SC, Lee WH, Lee EY. Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist. Science (New York, N.Y.). 314: 1467-70. PMID 17138902 DOI: 10.1126/Science.1130471 |
0.374 |
|
2006 |
Wu G, Lee WH. CtIP, a multivalent adaptor connecting transcriptional regulation, checkpoint control and tumor suppression. Cell Cycle (Georgetown, Tex.). 5: 1592-6. PMID 16880746 DOI: 10.4161/Cc.5.15.3127 |
0.375 |
|
2006 |
Furuta S, Wang JM, Wei S, Jeng YM, Jiang X, Gu B, Chen PL, Lee EY, Lee WH. Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature. Cancer Cell. 10: 13-24. PMID 16843262 DOI: 10.1016/J.Ccr.2006.05.022 |
0.718 |
|
2006 |
Liu F, Lee WH. CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression. Molecular and Cellular Biology. 26: 3124-34. PMID 16581787 DOI: 10.1128/Mcb.26.8.3124-3134.2006 |
0.343 |
|
2005 |
Furuta S, Jiang X, Gu B, Cheng E, Chen PL, Lee WH. Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 9176-81. PMID 15967981 DOI: 10.1073/Pnas.0503793102 |
0.74 |
|
2004 |
Beischlag TV, Taylor RT, Rose DW, Yoon D, Chen Y, Lee WH, Rosenfeld MG, Hankinson O. Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia. The Journal of Biological Chemistry. 279: 54620-8. PMID 15485806 DOI: 10.1074/Jbc.M410456200 |
0.336 |
|
2004 |
Utomo A, Jiang X, Furuta S, Yun J, Levin DS, Wang YC, Desai KV, Green JE, Chen PL, Lee WH. Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells. The Journal of Biological Chemistry. 279: 43522-9. PMID 15294905 DOI: 10.1074/Jbc.M407141200 |
0.727 |
|
2004 |
Ting NS, Lee WH. The DNA double-strand break response pathway: becoming more BRCAish than ever. Dna Repair. 3: 935-44. PMID 15279779 DOI: 10.1016/J.Dnarep.2004.03.026 |
0.36 |
|
2004 |
Lin SC, Lee KF, Nikitin AY, Hilsenbeck SG, Cardiff RD, Li A, Kang KW, Frank SA, Lee WH, Lee EY. Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis. Cancer Research. 64: 3525-32. PMID 15150107 DOI: 10.1158/0008-5472.Can-03-3524 |
0.369 |
|
2004 |
Shu Z, Vijayakumar S, Chen CF, Chen PL, Lee WH. Purified human SUV3p exhibits multiple-substrate unwinding activity upon conformational change. Biochemistry. 43: 4781-90. PMID 15096047 DOI: 10.1021/Bi0356449 |
0.349 |
|
2003 |
Yun J, Lee WH. Degradation of transcription repressor ZBRK1 through the ubiquitin-proteasome pathway relieves repression of Gadd45a upon DNA damage. Molecular and Cellular Biology. 23: 7305-14. PMID 14517299 DOI: 10.1128/Mcb.23.20.7305-7314.2003 |
0.323 |
|
2003 |
Lin HR, Ting NS, Qin J, Lee WH. M phase-specific phosphorylation of BRCA2 by Polo-like kinase 1 correlates with the dissociation of the BRCA2-P/CAF complex. The Journal of Biological Chemistry. 278: 35979-87. PMID 12815053 DOI: 10.1074/Jbc.M210659200 |
0.396 |
|
2003 |
Wu G, Jiang X, Lee WH, Chen PL. Assembly of functional ALT-associated promyelocytic leukemia bodies requires Nijmegen Breakage Syndrome 1. Cancer Research. 63: 2589-95. PMID 12750284 |
0.318 |
|
2002 |
Chen Y, Riley DJ, Zheng L, Chen PL, Lee WH. Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation Journal of Biological Chemistry. 277: 49408-49416. PMID 12386167 DOI: 10.1074/jbc.M207069200 |
0.318 |
|
2002 |
Zheng L, Lee WH. Retinoblastoma tumor suppressor and genome stability. Advances in Cancer Research. 85: 13-50. PMID 12374284 |
0.305 |
|
2001 |
Lee WH, Boyer TG. BRCA1 and BRCA2 in breast cancer Lancet. 358. PMID 11784554 DOI: 10.1016/S0140-6736(01)07018-0 |
0.308 |
|
2001 |
Xiao J, Liu C, Chen P, Lee W. RINT-1, a Novel Rad50-interacting Protein, Participates in Radiation-induced G2/M Checkpoint Control Journal of Biological Chemistry. 276: 6105-6111. PMID 11096100 DOI: 10.1074/Jbc.M008893200 |
0.42 |
|
2001 |
Li S, Ting NSY, Zheng L, Chen P, Lee W. Effect of DNA damage on a BRCA1 complex Nature. 414: 36-36. DOI: 10.1038/35102121 |
0.329 |
|
2000 |
Zheng L, Li S, Boyer TG, Lee WH. Lessons learned from BRCA1 and BRCA2. Oncogene. 19: 6159-75. PMID 11156530 DOI: 10.1038/Sj.Onc.1203968 |
0.424 |
|
2000 |
Wu G, Lee W, Chen P. NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres. Journal of Biological Chemistry. 275: 30618-30622. PMID 10913111 DOI: 10.1074/Jbc.C000390200 |
0.381 |
|
1999 |
Utomo AR, Nikitin AY, Lee WH. Temporal, spatial, and cell type-specific control of Cre-mediated DNA recombination in transgenic mice. Nature Biotechnology. 17: 1091-6. PMID 10545915 DOI: 10.1038/15073 |
0.327 |
|
1999 |
Chen Y, Lee W, Chew HK. Emerging roles of BRCA1 in transcriptional regulation and DNA repair. Journal of Cellular Physiology. 181: 385-392. PMID 10528224 DOI: 10.1002/(Sici)1097-4652(199912)181:3<385::Aid-Jcp2>3.0.Co;2-4 |
0.417 |
|
1998 |
Baer R, Lee WH. Functional Domains of the BRCA1 and BRCA2 Proteins Journal of Mammary Gland Biology and Neoplasia. 3: 403-412. PMID 10819534 DOI: 10.1023/A:1018736115722 |
0.416 |
|
1998 |
Li S, Ku CY, Farmer AA, Cong YS, Chen CF, Lee WH. Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs. The Journal of Biological Chemistry. 273: 6183-9. PMID 9497340 DOI: 10.1074/Jbc.273.11.6183 |
0.398 |
|
1997 |
Chang KH, Chen Y, Chen TT, Chou WH, Chen PL, Ma YY, Yang-Feng TL, Leng X, Tsai MJ, O'Malley BW, Lee WH. A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein. Proceedings of the National Academy of Sciences of the United States of America. 94: 9040-5. PMID 9256431 DOI: 10.1073/Pnas.94.17.9040 |
0.358 |
|
1996 |
Shan B, Durfee T, Lee W. Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 93: 679-684. PMID 8570615 DOI: 10.1073/Pnas.93.2.679 |
0.403 |
|
1995 |
Zhu X, Mancini MA, Chang K, Liu C, Chen C, Shan B, Jones D, Yang-Feng TL, Lee W. Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression. Molecular and Cellular Biology. 15: 5017-5029. PMID 7651420 DOI: 10.1128/Mcb.15.9.5017 |
0.379 |
|
1995 |
Zhu X, Chang KH, He D, Mancini MA, Brinkley WR, Lee WH. The C terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization. The Journal of Biological Chemistry. 270: 19545-50. PMID 7642639 DOI: 10.1074/Jbc.270.33.19545 |
0.384 |
|
1995 |
Johnson EM, Chen PL, Krachmarov CP, Barr SM, Kanovsky M, Ma ZW, Lee WH. Association of human Pur alpha with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Pur alpha recognition element. The Journal of Biological Chemistry. 270: 24352-60. PMID 7592647 DOI: 10.1074/Jbc.270.41.24352 |
0.302 |
|
1994 |
Mancini MA, Shan B, Nickerson JA, Penman S, Lee WH. The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 418-22. PMID 8278403 DOI: 10.1073/Pnas.91.1.418 |
0.348 |
|
1994 |
Shan B, Chang C, Jones D, Lee W. The transcription factor E2F-1 mediates the autoregulation of RB gene expression. Molecular and Cellular Biology. 14: 299-309. PMID 8264596 DOI: 10.1128/Mcb.14.1.299 |
0.341 |
|
1994 |
Shan B, Lee WH. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis Molecular and Cellular Biology. 14: 8166-8173. PMID 7969153 DOI: 10.1128/Mcb.14.12.8166 |
0.376 |
|
1994 |
Chen Y, Chen P, Lee W. Hot-spot p53 mutants interact specifically with two cellular proteins during progression of the cell cycle. Molecular and Cellular Biology. 14: 6764-6772. PMID 7935394 DOI: 10.1128/Mcb.14.10.6764 |
0.395 |
|
1994 |
Riley DJ, Lee EYHP, Lee WH. The retinoblastoma protein: More than a tumor suppressor Annual Review of Cell Biology. 10: 1-29. PMID 7888173 DOI: 10.1146/Annurev.Cb.10.110194.000245 |
0.392 |
|
1994 |
Durfee T, Mancini MA, Jones D, Elledge SJ, Lee W. The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing. Journal of Cell Biology. 127: 609-622. PMID 7525595 DOI: 10.1083/Jcb.127.3.609 |
0.403 |
|
1993 |
Hollingsworth RE, Chen P, Lee W. Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein. Current Opinion in Cell Biology. 5: 194-200. PMID 8507491 DOI: 10.1016/0955-0674(93)90102-V |
0.37 |
|
1993 |
Goodrich DW, Lee WH. Molecular characterization of the retinoblastoma susceptibility gene Bba - Reviews On Cancer. 1155: 43-61. PMID 8504130 DOI: 10.1016/0304-419X(93)90021-4 |
0.41 |
|
1993 |
Hollingsworth RE, Hensey CE, Lee W. Retinoblastoma protein and the cell cycle. Current Opinion in Genetics & Development. 3: 55-62. PMID 8453276 DOI: 10.1016/S0959-437X(05)80341-7 |
0.36 |
|
1993 |
Durfee T, Becherer K, Chen P, Yeh S, Yang Y, Kilburn AE, Lee W, Elledge SJ. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes & Development. 7: 555-569. PMID 8384581 DOI: 10.1101/Gad.7.4.555 |
0.386 |
|
1993 |
Lee WH. Tumor suppressor genes - The hope Faseb Journal. 7: 819. PMID 8344480 DOI: 10.1096/Fasebj.7.10.8344480 |
0.304 |
|
1992 |
Goodrich DW, Lee WH. Abrogation by c-myc of Gl phase arrest induced by RB protein but not by p53 Nature. 360: 177-179. PMID 1436095 DOI: 10.1038/360177A0 |
0.324 |
|
1992 |
Lee EY, Chang CY, Hu N, Wang YC, Lai CC, Herrup K, Lee WH, Bradley A. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature. 359: 288-94. PMID 1406932 DOI: 10.1038/359288A0 |
0.336 |
|
1991 |
Huang S, Lee WH, Lee EY. A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product. Nature. 350: 160-2. PMID 2005966 DOI: 10.1038/350160A0 |
0.38 |
|
1991 |
Hong F, Lee WH. Sequence similarity between part of human retinoblastoma susceptibility gene product and a neurofilament protein subunit Bioscience Reports. 11: 159-163. PMID 1958811 DOI: 10.1007/Bf01182484 |
0.351 |
|
1991 |
Lee EY-P, Bookstein R, Lee W. Role of the retinoblastoma gene in the oncogenesis of human breast carcinoma Cancer Treatment and Research. 53: 23-44. PMID 1672079 DOI: 10.1007/978-1-4615-3940-7_2 |
0.42 |
|
1991 |
Goodrich DW, Wang NP, Qian Y, Lee EY-P, Lee W. The Retinoblastoma Gene Product Regulates Progression Through the G1 Phase of the Cell Cycle Cell. 67: 293-302. PMID 1655277 DOI: 10.1016/0092-8674(91)90181-W |
0.354 |
|
1991 |
Lin BT-, Gruenwald S, Morla AO, Lee W, Wang JYJ. Retinoblastoma Cancer Suppressor Gene Product Is A Substrate Of The Cell Cycle Regulator Cdc2 Kinase The Embo Journal. 10: 857-864. DOI: 10.1002/J.1460-2075.1991.Tb08018.X |
0.36 |
|
1990 |
Bookstein R, Shew J, Chen P, Scully P, Lee W. Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene Science. 247: 712-715. PMID 2300823 DOI: 10.1126/Science.2300823 |
0.419 |
|
1990 |
Chen P, Chen Y, Bookstein R, Lee W. Genetic mechanisms of tumor suppression by the human p53 gene. Science. 250: 1576-1580. PMID 2274789 DOI: 10.1126/Science.2274789 |
0.325 |
|
1990 |
Bookstein R, Rio P, Madreperla SA, Hong F, Allred C, Grizzle WE, Lee W. Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 87: 7762-7766. PMID 2217208 DOI: 10.1073/Pnas.87.19.7762 |
0.343 |
|
1990 |
Shew J, Lin BTY, Chen P, Tseng BY, Yang-Feng TL, Lee W. C-terminal truncation of the retinoblastoma gene product leads to functional inactivation Proceedings of the National Academy of Sciences of the United States of America. 87: 6-10. PMID 1688660 DOI: 10.1073/Pnas.87.1.6 |
0.441 |
|
1990 |
Lai CC, Lee WH. Human retinoblastoma susceptibility gene Genetic Engineering. 12: 21-35. PMID 1366702 DOI: 10.1007/978-1-4613-0641-2_2 |
0.387 |
|
1990 |
Cheng J, Scully P, Shew J, Lee W, Vila V, Haas M. Homozygous deletion of the retinoblastoma gene in an acute lymphoblastic leukemia (T) cell line. Blood. 75: 730-735. DOI: 10.1182/Blood.V75.3.730.Bloodjournal753730 |
0.352 |
|
1990 |
Huang S, Wang N, Tseng BY, Lee W, Lee EH-P. Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen. The Embo Journal. 9: 1815-1822. DOI: 10.1002/J.1460-2075.1990.Tb08306.X |
0.368 |
|
1989 |
Hong FD, Huang HJ, To H, Young LJ, Oro A, Bookstein R, Lee EY, Lee WH. Structure of the human retinoblastoma gene. Proceedings of the National Academy of Sciences of the United States of America. 86: 5502-6. PMID 2748600 DOI: 10.1073/Pnas.86.14.5502 |
0.376 |
|
1989 |
Bookstein R, Lee EY-P, Peccei A, Lee W. Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line Molecular and Cellular Biology. 9: 1628-1634. PMID 2725521 DOI: 10.1128/Mcb.9.4.1628 |
0.38 |
|
1989 |
Chen P, Scully P, Shew J, Wang JYJ, Lee W. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell. 58: 1193-1198. PMID 2673546 DOI: 10.1016/0092-8674(89)90517-5 |
0.401 |
|
1988 |
Lee EY, Bookstein R, Young LJ, Lin CJ, Rosenfeld MG, Lee WH. Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79. Proceedings of the National Academy of Sciences of the United States of America. 85: 6017-21. PMID 3413073 DOI: 10.1073/Pnas.85.16.6017 |
0.377 |
|
1988 |
Lee EYHP, To H, Shew J, Bookstein R, Scully P, Lee W. Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science. 241: 218-221. PMID 3388033 DOI: 10.1126/Science.3388033 |
0.381 |
|
1988 |
Huang HJ, Yee JK, Shew JY, Chen PL, Bookstein R, Friedmann T, Lee EY, Lee WH. Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells. Science (New York, N.Y.). 242: 1563-6. PMID 3201247 DOI: 10.1126/Science.3201247 |
0.356 |
|
1988 |
Young LJ, Lee EY, To HA, Bookstein R, Shew JY, Donoso LA, Sery T, Giblin M, Shields JA, Lee WH. Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma. Human Genetics. 79: 137-41. PMID 3164702 DOI: 10.1007/Bf00280552 |
0.321 |
|
1988 |
Lee W, Bookstein R, Lee EYP. Studies on the human retinoblastoma susceptibility gene. Journal of Cellular Biochemistry. 38: 213-227. PMID 3068232 DOI: 10.1002/Jcb.240380309 |
0.349 |
|
1988 |
Bookstein R, Lee EY, To H, Young LJ, Sery TW, Hayes RC, Friedmann T, Lee WH. Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants. Proceedings of the National Academy of Sciences of the United States of America. 85: 2210-4. PMID 2895471 DOI: 10.1073/Pnas.85.7.2210 |
0.326 |
|
1988 |
DeCaprio JA, Ludlow JW, Figge J, Shew JY, Huang CM, Lee WH, Marsilio E, Paucha E, Livingston DM. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene Cell. 54: 275-283. PMID 2839300 DOI: 10.1016/0092-8674(88)90559-4 |
0.301 |
|
1988 |
Mendoza AE, Shew JY, Lee EY, Bookstein R, Lee WH. A case of synovial sarcoma with abnormal expression of the human retinoblastoma susceptibility gene. Human Pathology. 19: 487-9. PMID 2835305 DOI: 10.1016/S0046-8177(88)80504-5 |
0.353 |
|
1987 |
Lee WH, Bookstein R, Hong F, Young LJ, Shew JY, Lee EY. Human retinoblastoma susceptibility gene: cloning, identification, and sequence. Science (New York, N.Y.). 235: 1394-9. PMID 3823889 DOI: 10.1126/Science.3823889 |
0.402 |
|
1987 |
Lee WH, Shew JY, Hong FD, Sery TW, Donoso LA, Young LJ, Bookstein R, Lee EY. The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity. Nature. 329: 642-5. PMID 3657987 DOI: 10.1038/329642A0 |
0.384 |
|
1986 |
Chen L, Hatada E, Wheatley W, Lee W. Single amino acid substitution, from Glu1025 to Asp, of the fps oncogenic protein causes temperature sensitivity in transformation and kinase activity Virology. 155: 106-119. PMID 2877522 DOI: 10.1016/0042-6822(86)90172-8 |
0.314 |
|
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