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82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Porterfield V, Khan SS, Foff EP, Koseoglu MM, Blanco IK, Jayaraman S, Lien E, McConnell MJ, Bloom GS, Lazo JS, Sharlow ER. A three-dimensional dementia model reveals spontaneous cell cycle re-entry and a senescence-associated secretory phenotype. Neurobiology of Aging. PMID 32184029 DOI: 10.1016/j.neurobiolaging.2020.02.011  0.92
2019 Rudenko LK, Wallrabe H, Periasamy A, Siller KH, Svindrych Z, Seward ME, Best MN, Bloom GS. Intraneuronal Tau Misfolding Induced by Extracellular Amyloid-β Oligomers. Journal of Alzheimer's Disease : Jad. PMID 31524157 DOI: 10.3233/JAD-190226  0.96
2018 Koseoglu MM, Norambuena A, Sharlow ER, Lazo JS, Bloom GS. Aberrant Neuronal Cell Cycle Re-Entry: The Pathological Confluence of Alzheimer's Disease and Brain Insulin Resistance, and Its Relation to Cancer. Journal of Alzheimer's Disease : Jad. PMID 30452418 DOI: 10.3233/JAD-180874  0.32
2018 Norambuena A, Wallrabe H, Cao R, Wang DB, Silva A, Svindrych Z, Periasamy A, Hu S, Tanzi RE, Kim DY, Bloom GS. A novel lysosome-to-mitochondria signaling pathway disrupted by amyloid-β oligomers. The Embo Journal. PMID 30348864 DOI: 10.15252/embj.2018100241  0.64
2018 Kodis EJ, Choi S, Swanson E, Ferreira G, Bloom GS. N-methyl-D-aspartate receptor-mediated calcium influx connects amyloid-β oligomers to ectopic neuronal cell cycle reentry in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 14: 1302-1312. PMID 30293574 DOI: 10.1016/j.jalz.2018.05.017  0.32
2018 Khan SS, LaCroix M, Boyle G, Sherman MA, Brown JL, Amar F, Aldaco J, Lee MK, Bloom GS, Lesné SE. Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons. Acta Neuropathologica. PMID 29995210 DOI: 10.1007/s00401-018-1886-z  0.92
2017 Bloom GS, Lazo JS, Norambuena A. Reduced brain insulin signaling: A seminal process in Alzheimer's disease pathogenesis. Neuropharmacology. PMID 28965829 DOI: 10.1016/j.neuropharm.2017.09.016  0.32
2017 Swanson E, Breckenridge L, McMahon L, Som S, McConnell I, Bloom GS. Extracellular Tau Oligomers Induce Invasion of Endogenous Tau into the Somatodendritic Compartment and Axonal Transport Dysfunction. Journal of Alzheimer's Disease : Jad. PMID 28482642 DOI: 10.3233/JAD-170168  0.32
2016 Norambuena A, Wallrabe H, McMahon L, Silva A, Swanson E, Khan SS, Baerthlein D, Kodis E, Oddo S, Mandell JW, Bloom GS. mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27693185 DOI: 10.1016/j.jalz.2016.08.015  0.92
2016 Sharlow ER, Leimgruber S, Lira A, McConnell MJ, Norambuena A, Bloom GS, Epperly MW, Greenberger JS, Lazo JS. A small molecule screen exposes mTOR signaling pathway involvement in radiation-induced apoptosis. Acs Chemical Biology. PMID 26938669 DOI: 10.1021/acschembio.5b00909  0.32
2016 Khan SS, Bloom GS. Tau: The Center of a Signaling Nexus in Alzheimer's Disease. Frontiers in Neuroscience. 10: 31. PMID 26903798 DOI: 10.3389/fnins.2016.00031  0.92
2015 Fang X, Zhang B, Thisse B, Bloom GS, Thisse C. IQGAP3 Is Essential for Cell Proliferation and Motility During Zebrafish Embryonic Development. Cytoskeleton (Hoboken, N.J.). PMID 26286209 DOI: 10.1002/cm.21237  1
2015 Wallrabe H, Sun Y, Fang X, Periasamy A, Bloom GS. Three-color confocal Förster (or fluorescence) resonance energy transfer microscopy: Quantitative analysis of protein interactions in the nucleation of actin filaments in live cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 87: 580-8. PMID 25755111 DOI: 10.1002/cyto.a.22651  1
2014 Marbiah MM, Harvey A, West BT, Louzolo A, Banerjee P, Alden J, Grigoriadis A, Hummerich H, Kan HM, Cai Y, Bloom GS, Jat P, Collinge J, Klöhn PC. Identification of a gene regulatory network associated with prion replication. The Embo Journal. 33: 1527-47. PMID 24843046 DOI: 10.15252/embj.201387150  1
2014 Bloom GS. Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis. Jama Neurology. 71: 505-8. PMID 24493463 DOI: 10.1001/jamaneurol.2013.5847  1
2013 Wallrabe H, Cai Y, Sun Y, Periasamy A, Luzes R, Fang X, Kan HM, Cameron LC, Schafer DA, Bloom GS. IQGAP1 interactome analysis by in vitro reconstitution and live cell 3-color FRET microscopy. Cytoskeleton (Hoboken, N.J.). 70: 819-36. PMID 24124181 DOI: 10.1002/cm.21146  1
2013 Osman MA, Bloom GS, Tagoe EA. Helicobacter pylori-induced alteration of epithelial cell signaling and polarity: a possible mechanism of gastric carcinoma etiology and disparity. Cytoskeleton (Hoboken, N.J.). 70: 349-59. PMID 23629919 DOI: 10.1002/cm.21114  1
2013 Liu C, Billadeau DD, Abdelhakim H, Leof E, Kaibuchi K, Bernabeu C, Bloom GS, Yang L, Boardman L, Shah VH, Kang N. IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver. The Journal of Clinical Investigation. 123: 1138-56. PMID 23454766 DOI: 10.1172/JCI63836  1
2013 Seward ME, Swanson E, Norambuena A, Reimann A, Cochran JN, Li R, Roberson ED, Bloom GS. Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease. Journal of Cell Science. 126: 1278-86. PMID 23345405 DOI: 10.1242/jcs.1125880  1
2013 Ferrer-Acosta Y, Rodríguez-Cruz EN, Orange F, De Jesús-Cortés H, Madera B, Vaquer-Alicea J, Ballester J, Guinel MJ, Bloom GS, Vega IE. EFhd2 is a novel amyloid protein associated with pathological tau in Alzheimer's disease. Journal of Neurochemistry. 125: 921-31. PMID 23331044 DOI: 10.1111/jnc.12155  1
2013 Nussbaum JM, Seward ME, Bloom GS. Alzheimer disease: a tale of two prions. Prion. 7: 14-9. PMID 22965142 DOI: 10.4161/pri.22118  1
2012 Nussbaum JM, Schilling S, Cynis H, Silva A, Swanson E, Wangsanut T, Tayler K, Wiltgen B, Hatami A, Rönicke R, Reymann K, Hutter-Paier B, Alexandru A, Jagla W, Graubner S, ... ... Bloom GS, et al. Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β. Nature. 485: 651-5. PMID 22660329 DOI: 10.1038/nature11060  1
2012 Wallrabe H, Sun Y, Fang X, Periasamy A, Bloom G. Three-color FRET expands the ability to quantify the interactions of several proteins involved in actin filament nucleation Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8226. DOI: 10.1117/12.906432  1
2009 Bamburg JR, Bloom GS. Cytoskeletal pathologies of Alzheimer disease. Cell Motility and the Cytoskeleton. 66: 635-49. PMID 19479823 DOI: 10.1002/cm.20388  1
2009 Yan J, Yang Y, Zhang H, King C, Kan HM, Cai Y, Yuan CX, Bloom GS, Hua X. Menin interacts with IQGAP1 to enhance intercellular adhesion of beta-cells. Oncogene. 28: 973-82. PMID 19079338 DOI: 10.1038/onc.2008.435  1
2007 Benseñor LB, Kan HM, Wang N, Wallrabe H, Davidson LA, Cai Y, Schafer DA, Bloom GS. IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly. Journal of Cell Science. 120: 658-69. PMID 17264147 DOI: 10.1242/jcs.03376  1
2006 King ME, Kan HM, Baas PW, Erisir A, Glabe CG, Bloom GS. Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid. The Journal of Cell Biology. 175: 541-6. PMID 17101697 DOI: 10.1083/jcb.200605187  1
2006 Bloom GS. Intracellular trafficking and the cytoskeleton Traffic. 7: 489. DOI: 10.1111/j.1600-0854.2006.00404.x  1
2005 Bloom GS, Ren K, Glabe CG. Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid. Biochimica Et Biophysica Acta. 1739: 116-24. PMID 15615631 DOI: 10.1016/j.bbadis.2004.08.008  1
2005 Morris LE, Bloom GS, Frierson HF, Powell SM. Nucleotide variants within the IQGAP1 gene in diffuse-type gastric cancers. Genes, Chromosomes & Cancer. 42: 280-6. PMID 15611933 DOI: 10.1002/gcc.20150  1
2005 Bloom GS, King ME, Binder LI. Biochimica et Biophysica Acta - Molecular Basis of Disease: Preface Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1739: 89-90. DOI: 10.1016/j.bbadis.2004.08.012  1
2004 Mateer SC, Morris LE, Cromer DA, Benseñor LB, Bloom GS. Actin filament binding by a monomeric IQGAP1 fragment with a single calponin homology domain. Cell Motility and the Cytoskeleton. 58: 231-41. PMID 15236354 DOI: 10.1002/cm.20013  1
2004 Yamaoka-Tojo M, Ushio-Fukai M, Hilenski L, Dikalov SI, Chen YE, Tojo T, Fukai T, Fujimoto M, Patrushev NA, Wang N, Kontos CD, Bloom GS, Alexander RW. IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. Circulation Research. 95: 276-83. PMID 15217908 DOI: 10.1161/01.RES.0000136522.58649.60  1
2003 Mateer SC, Wang N, Bloom GS. IQGAPs: integrators of the cytoskeleton, cell adhesion machinery, and signaling networks. Cell Motility and the Cytoskeleton. 55: 147-55. PMID 12789660 DOI: 10.1002/cm.10118  1
2002 Mundy DI, Machleidt T, Ying YS, Anderson RG, Bloom GS. Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton. Journal of Cell Science. 115: 4327-39. PMID 12376564 DOI: 10.1242/jcs.00117  1
2002 Mateer SC, McDaniel AE, Nicolas V, Habermacher GM, Lin MJ, Cromer DA, King ME, Bloom GS. The mechanism for regulation of the F-actin binding activity of IQGAP1 by calcium/calmodulin. The Journal of Biological Chemistry. 277: 12324-33. PMID 11809768 DOI: 10.1074/jbc.M109535200  1
2001 Bloom GS. The UNC-104/KIF1 family of kinesins. Current Opinion in Cell Biology. 13: 36-40. PMID 11163131 DOI: 10.1016/S0955-0674(00)00171-X  1
2000 Bloom GS. Biochimica et Biophysica Acta - Molecular Cell Research: Preface Biochimica Et Biophysica Acta - Molecular Cell Research. 1496: 1-2. DOI: 10.1016/S0167-4889(00)00004-5  1
1999 Sontag E, Nunbhakdi-Craig V, Lee G, Brandt R, Kamibayashi C, Kuret J, White CL, Mumby MC, Bloom GS. Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies. The Journal of Biological Chemistry. 274: 25490-8. PMID 10464280 DOI: 10.1074/jbc.274.36.25490  1
1998 Fullerton AT, Bau MY, Conrad PA, Bloom GS. In vitro reconstitution of microtubule plus end-directed, GTPgammaS-sensitive motility of Golgi membranes. Molecular Biology of the Cell. 9: 2699-714. PMID 9763438  1
1998 Ratner N, Bloom GS, Brady ST. A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7717-26. PMID 9742142  1
1998 Bashour AM, Bloom GS. 58K, a microtubule-binding Golgi protein, is a formiminotransferase cyclodeaminase. The Journal of Biological Chemistry. 273: 19612-7. PMID 9677387 DOI: 10.1074/jbc.273.31.19612  1
1998 Bloom GS, Goldstein LS. Cruising along microtubule highways: how membranes move through the secretory pathway. The Journal of Cell Biology. 140: 1277-80. PMID 9508761  1
1997 Bashour AM, Fullerton AT, Hart MJ, Bloom GS. IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments. The Journal of Cell Biology. 137: 1555-66. PMID 9199170 DOI: 10.1083/jcb.137.7.1555  1
1996 Biesiada E, Adams PM, Shanklin DR, Bloom GS, Stein SA. Biology of the congenitally hypothyroid hyt/hyt mouse. Advances in Neuroimmunology. 6: 309-46. PMID 9183515 DOI: 10.1016/S0960-5428(97)00028-9  1
1996 Sontag E, Nunbhakdi-Craig V, Lee G, Bloom GS, Mumby MC. Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A. Neuron. 17: 1201-7. PMID 8982166 DOI: 10.1016/S0896-6273(00)80250-0  1
1995 Bloom GS, Endow SA. Motor proteins 1: kinesins. Protein Profile. 2: 1105-71. PMID 8542443  1
1995 Conrad PA, Smart EJ, Ying YS, Anderson RG, Bloom GS. Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps. The Journal of Cell Biology. 131: 1421-33. PMID 8522601 DOI: 10.1083/jcb.131.6.1421  1
1995 Sontag E, Nunbhakdi-Craig V, Bloom GS, Mumby MC. A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle. The Journal of Cell Biology. 128: 1131-44. PMID 7896877 DOI: 10.1083/jcb.128.6.1131  1
1995 Lippincott-Schwartz J, Cole NB, Marotta A, Conrad PA, Bloom GS. Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic. The Journal of Cell Biology. 128: 293-306. PMID 7844144 DOI: 10.1083/jcb.128.3.293  1
1995 Elluru RG, Bloom GS, Brady ST. Fast axonal transport of kinesin in the rat visual system: functionality of kinesin heavy chain isoforms. Molecular Biology of the Cell. 6: 21-40. PMID 7538359  1
1994 Bloom GS, Endow SA. Motor proteins. 1: kinesins. Protein Profile. 1: 1059-116. PMID 8528901  1
1993 Bloom GS, Richards BW, Leopold PL, Ritchey DM, Brady ST. GTP gamma S inhibits organelle transport along axonal microtubules. The Journal of Cell Biology. 120: 467-76. PMID 7678421  1
1992 Bloom GS. Motor proteins for cytoplasmic microtubules. Current Opinion in Cell Biology. 4: 66-73. PMID 1532721  1
1992 Leopold PL, McDowall AW, Pfister KK, Bloom GS, Brady ST. Association of kinesin with characterized membrane-bounded organelles. Cell Motility and the Cytoskeleton. 23: 19-33. PMID 1382871 DOI: 10.1002/cm.970230104  1
1991 Cyr JL, Pfister KK, Bloom GS, Slaughter CA, Brady ST. Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 88: 10114-8. PMID 1946431  1
1991 Wagner MC, Pfister KK, Brady ST, Bloom GS. Purification of kinesin from bovine brain and assay of microtubule-stimulated ATPase activity. Methods in Enzymology. 196: 157-75. PMID 1851939  1
1991 Hirokawa N, Sato-Yoshitake R, Kobayashi N, Pfister KK, Bloom GS, Brady ST. Kinesin associates with anterogradely transported membranous organelles in vivo. The Journal of Cell Biology. 114: 295-302. PMID 1712789  1
1991 Ktistakis NT, Roth MG, Bloom GS. PtK1 cells contain a nondiffusible, dominant factor that makes the Golgi apparatus resistant to brefeldin A. The Journal of Cell Biology. 113: 1009-23. PMID 1710224  1
1991 Vallee RB, Bloom GS. Mechanisms of fast and slow axonal transport. Annual Review of Neuroscience. 14: 59-92. PMID 1709561 DOI: 10.1146/annurev.ne.14.030191.000423  1
1990 Donaldson JG, Lippincott-Schwartz J, Bloom GS, Kreis TE, Klausner RD. Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action. The Journal of Cell Biology. 111: 2295-306. PMID 2277061 DOI: 10.1083/jcb.111.6.2295  1
1990 Leopold PL, Snyder R, Bloom GS, Brady ST. Nucleotide specificity for the bidirectional transport of membrane-bounded organelles in isolated axoplasm. Cell Motility and the Cytoskeleton. 15: 210-9. PMID 1692515 DOI: 10.1002/cm.970150404  1
1990 Brady ST, Pfister KK, Bloom GS. A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm. Proceedings of the National Academy of Sciences of the United States of America. 87: 1061-5. PMID 1689058  1
1989 Bloom GS, Brashear TA. A novel 58-kDa protein associates with the Golgi apparatus and microtubules. The Journal of Biological Chemistry. 264: 16083-92. PMID 2777777  1
1989 Wagner MC, Pfister KK, Bloom GS, Brady ST. Copurification of kinesin polypeptides with microtubule-stimulated Mg-ATPase activity and kinetic analysis of enzymatic properties. Cell Motility and the Cytoskeleton. 12: 195-215. PMID 2524282 DOI: 10.1002/cm.970120403  1
1989 Pfister KK, Wagner MC, Stenoien DL, Brady ST, Bloom GS. Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells. The Journal of Cell Biology. 108: 1453-63. PMID 2522455  1
1989 Hirokawa N, Pfister KK, Yorifuji H, Wagner MC, Brady ST, Bloom GS. Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell. 56: 867-78. PMID 2522351 DOI: 10.1016/0092-8674(89)90691-0  1
1989 Pfister KK, Wagner MC, Bloom GS, Brady ST. Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role for sulfhydryls in fast axonal transport. Biochemistry. 28: 9006-12. PMID 2481499  1
1988 Bloom GS, Wagner MC, Pfister KK, Brady ST. Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide. Biochemistry. 27: 3409-16. PMID 3134048  1
1986 Bloom GS, Luca FC, Collins CA, Vallee RB. Isolation of mitotic microtubule-associated proteins from sea urchin eggs. Annals of the New York Academy of Sciences. 466: 328-39. PMID 3524371  1
1986 Vallee RB, Bloom GS, Luca FC. Differential structure and distribution of the high molecular weight brain microtubule-associated proteins, MAP-1 and MAP-2. Annals of the New York Academy of Sciences. 466: 134-44. PMID 3524368  1
1986 Luca FC, Bloom GS, Vallee RB. A monoclonal antibody that cross-reacts with phosphorylated epitopes on two microtubule-associated proteins and two neurofilament polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 83: 1006-10. PMID 2419894  1
1985 Bloom GS, Luca FC, Vallee RB. Cross-linking of intermediate filaments to microtubules by microtubule-associated protein 2. Annals of the New York Academy of Sciences. 455: 18-31. PMID 3909881  1
1985 Bloom GS, Luca FC, Vallee RB. Microtubule-associated protein 1B: identification of a major component of the neuronal cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 82: 5404-8. PMID 3895231  1
1985 Bloom GS, Luca FC, Collins CA, Vallee RB. Use of multiple monoclonal antibodies to characterize the major microtubule-associated protein in sea urchin eggs. Cell Motility. 5: 431-46. PMID 2866844  1
1985 Bloom GS, Luca FC, Vallee RB. Identification of high molecular weight microtubule-associated proteins in anterior pituitary tissue and cells using taxol-dependent purification combined with microtubule-associated protein specific antibodies. Biochemistry. 24: 4185-91. PMID 2864954  1
1985 Hirokawa N, Bloom GS, Vallee RB. Cytoskeletal architecture and immunocytochemical localization of microtubule-associated proteins in regions of axons associated with rapid axonal transport: the beta,beta'-iminodipropionitrile-intoxicated axon as a model system. The Journal of Cell Biology. 101: 227-39. PMID 2409096  1
1984 Bloom GS, Schoenfeld TA, Vallee RB. Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system. The Journal of Cell Biology. 98: 320-30. PMID 6368569  1
1984 Bloom GS, Luca FC, Vallee RB. Widespread cellular distribution of MAP-1A (microtubule-associated protein 1A) in the mitotic spindle and on interphase microtubules. The Journal of Cell Biology. 98: 331-40. PMID 6142895  1
1984 Vallee RB, Bloom GS, Theurkauf WE. Microtubule-associated proteins: subunits of the cytomatrix. The Journal of Cell Biology. 99: 38s-44s. PMID 6086669  1
1983 Bloom GS, Vallee RB. Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells. The Journal of Cell Biology. 96: 1523-31. PMID 6343400  1
1983 Vallee RB, Bloom GS. Isolation of sea urchin egg microtubules with taxol and identification of mitotic spindle microtubule-associated proteins with monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 80: 6259-63. PMID 6137821  1
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