William Theurkauf - Publications

University of Massachusetts Medical School, Worcester, MA, United States 

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhang G, Yu T, Parhad SS, Ho S, Weng Z, Theurkauf WE. piRNA-independent transposon silencing by the Drosophila THO complex. Developmental Cell. PMID 34547226 DOI: 10.1016/j.devcel.2021.08.021  1
2021 Yu T, Huang X, Dou S, Tang X, Luo S, Theurkauf WE, Lu J, Weng Z. A benchmark and an algorithm for detecting germline transposon insertions and measuring de novo transposon insertion frequencies. Nucleic Acids Research. PMID 33511407 DOI: 10.1093/nar/gkab010  1
2021 Yu T, Fan K, Özata DM, Zhang G, Fu Y, Theurkauf WE, Zamore PD, Weng Z. Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes. Nature Communications. 12: 73. PMID 33397987 DOI: 10.1038/s41467-020-20345-3  1
2020 Tsuji J, Thomson T, Chan E, Brown CK, Oppenheimer J, Bigelow C, Dong X, Theurkauf WE, Weng Z, Schwartz LM. HIGH RESOLUTION ANALYSIS OF DIFFERENTIAL GENE EXPRESSION DURING SKELETAL MUSCLE ATROPHY AND PROGRAMMED CELL DEATH. Physiological Genomics. PMID 32926651 DOI: 10.1152/Physiolgenomics.00047.2020  1
2020 Parhad SS, Yu T, Zhang G, Rice NP, Weng Z, Theurkauf WE. Adaptive Evolution Targets a piRNA Precursor Transcription Network. Cell Reports. 30: 2672-2685.e5. PMID 32101744 DOI: 10.1016/J.Celrep.2020.01.109  1
2019 Yu T, Koppetsch BS, Pagliarani S, Johnston S, Silverstein NJ, Luban J, Chappell K, Weng Z, Theurkauf WE. The piRNA Response to Retroviral Invasion of the Koala Genome. Cell. PMID 31607510 DOI: 10.1016/J.Cell.2019.09.002  1
2019 Parhad SS, Theurkauf WE. Rapid evolution and conserved function of the piRNA pathway. Open Biology. 9: 180181. PMID 30958115 DOI: 10.1098/rsob.180181  1
2018 Zhang G, Tu S, Yu T, Zhang XO, Parhad SS, Weng Z, Theurkauf WE. Co-dependent Assembly of Drosophila piRNA Precursor Complexes and piRNA Cluster Heterochromatin. Cell Reports. 24: 3413-3422.e4. PMID 30257203 DOI: 10.1016/J.Celrep.2018.08.081  1
2018 Yu B, Lin YA, Parhad SS, Jin Z, Ma J, Theurkauf WE, Zhang ZZ, Huang Y. Structural insights into Rhino-Deadlock complex for germline piRNA cluster specification. Embo Reports. PMID 29858487 DOI: 10.15252/embr.201745418  1
2017 Bozler J, Kacsoh BZ, Chen H, Theurkauf WE, Weng Z, Bosco G. A systems level approach to temporal expression dynamics in Drosophila reveals clusters of long term memory genes. Plos Genetics. 13: e1007054. PMID 29084214 DOI: 10.1371/Journal.Pgen.1007054  1
2017 Parhad SS, Tu S, Weng Z, Theurkauf WE. Adaptive Evolution Leads to Cross-Species Incompatibility in the piRNA Transposon Silencing Machinery. Developmental Cell. PMID 28919205 DOI: 10.1016/J.Devcel.2017.08.012  1
2014 Zhang Z, Wang J, Schultz N, Zhang F, Parhad SS, Tu S, Vreven T, Zamore PD, Weng Z, Theurkauf WE. The HP1 homolog rhino anchors a nuclear complex that suppresses piRNA precursor splicing. Cell. 157: 1353-63. PMID 24906152 DOI: 10.1016/J.Cell.2014.04.030  1
2014 Zhuang J, Wang J, Theurkauf W, Weng Z. TEMP: a computational method for analyzing transposable element polymorphism in populations. Nucleic Acids Research. 42: 6826-38. PMID 24753423 DOI: 10.1093/Nar/Gku323  1
2014 Zhang Z, Koppetsch BS, Wang J, Tipping C, Weng Z, Theurkauf WE, Zamore PD. Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin. The Embo Journal. 33: 536-9. PMID 24652836 DOI: 10.1002/Embj.201384895  1
2013 Perrat PN, DasGupta S, Wang J, Theurkauf W, Weng Z, Rosbash M, Waddell S. Transposition-driven genomic heterogeneity in the Drosophila brain. Science (New York, N.Y.). 340: 91-5. PMID 23559253 DOI: 10.1126/Science.1231965  1
2013 Simkin A, Wong A, Poh YP, Theurkauf WE, Jensen JD. Recurrent and recent selective sweeps in the piRNA pathway. Evolution; International Journal of Organic Evolution. 67: 1081-90. PMID 23550757 DOI: 10.1111/Evo.12011  1
2012 Zhang Z, Theurkauf WE, Weng Z, Zamore PD. Strand-specific libraries for high throughput RNA sequencing (RNA-Seq) prepared without poly(A) selection. Silence. 3: 9. PMID 23273270 DOI: 10.1186/1758-907X-3-9  1
2012 Zhang F, Wang J, Xu J, Zhang Z, Koppetsch BS, Schultz N, Vreven T, Meignin C, Davis I, Zamore PD, Weng Z, Theurkauf WE. UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell. 151: 871-84. PMID 23141543 DOI: 10.1016/J.Cell.2012.09.040  1
2011 Khurana JS, Wang J, Xu J, Koppetsch BS, Thomson TC, Nowosielska A, Li C, Zamore PD, Weng Z, Theurkauf WE. Adaptation to P element transposon invasion in Drosophila melanogaster. Cell. 147: 1551-63. PMID 22196730 DOI: 10.1016/J.Cell.2011.11.042  1
2011 Zhang Z, Xu J, Koppetsch BS, Wang J, Tipping C, Ma S, Weng Z, Theurkauf WE, Zamore PD. Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains. Molecular Cell. 44: 572-84. PMID 22099305 DOI: 10.1016/J.Molcel.2011.10.011  1
2011 Theurkauf W. Transposon Silencing of Small RNAs Developmental Cell. 21: e3. DOI: 10.1016/J.Devcel.2011.07.010  1
2010 Khurana JS, Xu J, Weng Z, Theurkauf WE. Distinct functions for the Drosophila piRNA pathway in genome maintenance and telomere protection. Plos Genetics. 6: e1001246. PMID 21179579 DOI: 10.1371/Journal.Pgen.1001246  1
2010 Khurana JS, Theurkauf W. piRNAs, transposon silencing, and Drosophila germline development. The Journal of Cell Biology. 191: 905-13. PMID 21115802 DOI: 10.1083/Jcb.201006034  1
2010 Theurkauf W. William Theurkauf. Current Biology : Cb. 20: R389-90. PMID 20468083  1
2010 Varmark H, Kwak S, Theurkauf WE. A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells. Cell Cycle (Georgetown, Tex.). 9: 312-20. PMID 20023427 DOI: 10.4161/cc.9.2.10418  1
2009 Klattenhoff C, Xi H, Li C, Lee S, Xu J, Khurana JS, Zhang F, Schultz N, Koppetsch BS, Nowosielska A, Seitz H, Zamore PD, Weng Z, Theurkauf WE. The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters. Cell. 138: 1137-49. PMID 19732946 DOI: 10.1016/J.Cell.2009.07.014  1
2009 Varmark H, Sparks CA, Nordberg JJ, Koppetsch BS, Theurkauf WE. DNA damage-induced cell death is enhanced by progression through mitosis. Cell Cycle (Georgetown, Tex.). 8: 2951-63. PMID 19713770  1
2009 Li C, Vagin VV, Lee S, Xu J, Ma S, Xi H, Seitz H, Horwich MD, Syrzycka M, Honda BM, Kittler EL, Zapp ML, Klattenhoff C, Schulz N, Theurkauf WE, et al. Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell. 137: 509-21. PMID 19395009 DOI: 10.1016/J.Cell.2009.04.027  1
2009 Benoit B, He CH, Zhang F, Votruba SM, Tadros W, Westwood JT, Smibert CA, Lipshitz HD, Theurkauf WE. An essential role for the RNA-binding protein Smaug during the Drosophila maternal-to-zygotic transition. Development (Cambridge, England). 136: 923-32. PMID 19234062 DOI: 10.1242/Dev.031815  1
2008 Blumenstiel JP, Fu R, Theurkauf WE, Hawley RS. Components of the RNAi machinery that mediate long-distance chromosomal associations are dispensable for meiotic and early somatic homolog pairing in Drosophila melanogaster. Genetics. 180: 1355-65. PMID 18791234 DOI: 10.1534/genetics.108.092650  1
2008 Klattenhoff C, Theurkauf W. Biogenesis and germline functions of piRNAs. Development (Cambridge, England). 135: 3-9. PMID 18032451 DOI: 10.1242/dev.006486  1
2007 Takada S, Kwak S, Koppetsch BS, Theurkauf WE. grp (chk1) replication-checkpoint mutations and DNA damage trigger a Chk2-dependent block at the Drosophila midblastula transition. Development (Cambridge, England). 134: 1737-44. PMID 17409117 DOI: 10.1242/dev.02831  1
2007 Klattenhoff C, Bratu DP, McGinnis-Schultz N, Koppetsch BS, Cook HA, Theurkauf WE. Drosophila rasiRNA pathway mutations disrupt embryonic axis specification through activation of an ATR/Chk2 DNA damage response. Developmental Cell. 12: 45-55. PMID 17199040 DOI: 10.1016/j.devcel.2006.12.001  1
2006 Theurkauf WE, Klattenhoff C, Bratu DP, McGinnis-Schultz N, Koppetsch BS, Cook HA. rasiRNAs, DNA damage, and embryonic axis specification. Cold Spring Harbor Symposia On Quantitative Biology. 71: 171-80. PMID 17381294 DOI: 10.1101/Sqb.2006.71.066  1
2005 Doxsey S, McCollum D, Theurkauf W. Centrosomes in cellular regulation. Annual Review of Cell and Developmental Biology. 21: 411-34. PMID 16212501 DOI: 10.1146/Annurev.Cellbio.21.122303.120418  1
2005 Serbus LR, Cha BJ, Theurkauf WE, Saxton WM. Dynein and the actin cytoskeleton control kinesin-driven cytoplasmic streaming in Drosophila oocytes. Development (Cambridge, England). 132: 3743-52. PMID 16077093 DOI: 10.1242/Dev.01956  1
2005 Förstemann K, Tomari Y, Du T, Vagin VV, Denli AM, Bratu DP, Klattenhoff C, Theurkauf WE, Zamore PD. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. Plos Biology. 3: e236. PMID 15918770 DOI: 10.1371/Journal.Pbio.0030236  1
2005 Sibon OCM, Theurkauf WE. Centrosome Regulation in Response to Environmental and Genotoxic Stress Centrosomes in Development and Disease. 211-223. DOI: 10.1002/3527603808.ch11  1
2004 Tomari Y, Du T, Haley B, Schwarz DS, Bennett R, Cook HA, Koppetsch BS, Theurkauf WE, Zamore PD. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell. 116: 831-41. PMID 15035985 DOI: 10.1016/S0092-8674(04)00218-1  1
2004 Cook HA, Koppetsch BS, Wu J, Theurkauf WE. The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. Cell. 116: 817-29. PMID 15035984 DOI: 10.1016/S0092-8674(04)00250-8  1
2003 Takada S, Kelkar A, Theurkauf WE. Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity. Cell. 113: 87-99. PMID 12679037 DOI: 10.1016/S0092-8674(03)00202-2  1
2003 Arn EA, Cha BJ, Theurkauf WE, Macdonald PM. Recognition of a bicoid mRNA localization signal by a protein complex containing Swallow, Nod, and RNA binding proteins. Developmental Cell. 4: 41-51. PMID 12530962 DOI: 10.1016/S1534-5807(02)00397-0  1
2002 Cha BJ, Serbus LR, Koppetsch BS, Theurkauf WE. Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior. Nature Cell Biology. 4: 592-8. PMID 12134163 DOI: 10.1038/Ncb832  1
2002 Stevenson V, Hudson A, Cooley L, Theurkauf WE. Arp2/3-dependent pseudocleavage [correction of psuedocleavage] furrow assembly in syncytial Drosophila embryos. Current Biology : Cb. 12: 705-11. PMID 12007413 DOI: 10.1016/S0960-9822(02)00807-2  1
2001 Cha BJ, Koppetsch BS, Theurkauf WE. In vivo analysis of Drosophila bicoid mRNA localization reveals a novel microtubule-dependent axis specification pathway. Cell. 106: 35-46. PMID 11461700 DOI: 10.1016/S0092-8674(01)00419-6  1
2001 Richter JD, Theurkauf WE. Development. The message is in the translation. Science (New York, N.Y.). 293: 60-2. PMID 11441171 DOI: 10.1126/science.1062237  1
2001 Theurkauf WE. TACCing down the spindle poles. Nature Cell Biology. 3: E159-61. PMID 11433309 DOI: 10.1038/35083110  1
2001 Stevenson VA, Kramer J, Kuhn J, Theurkauf WE. Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization. Nature Cell Biology. 3: 68-75. PMID 11146628 DOI: 10.1038/35050579  1
2001 Stevenson VA, Theurkauf WE. What is the maximum stretching for C-C single bond? Journal of Molecular Structure: Theochem. 540: 131-138. DOI: 10.1016/S0166-1280(00)00721-1  1
2001 Cha B, Theurkauf W. Pictures in cell biology: In vivo analysis of bicoid RNA transport Trends in Cell Biology. 11: 365.  1
2000 Groisman I, Huang YS, Mendez R, Cao Q, Theurkauf W, Richter JD. CPEB, maskin, and cyclin B1 mRNA at the mitotic apparatus: implications for local translational control of cell division. Cell. 103: 435-47. PMID 11081630 DOI: 10.1016/S0092-8674(00)00135-5  1
2000 Stevenson VA, Theurkauf WE. Actin cytoskeleton: putting a CAP on actin polymerization. Current Biology : Cb. 10: R695-7. PMID 11050402 DOI: 10.1016/S0960-9822(00)00712-0  1
2000 Guilherme A, Emoto M, Buxton JM, Bose S, Sabini R, Theurkauf WE, Leszyk J, Czech MP. Perinuclear localization and insulin responsiveness of GLUT4 requires cytoskeletal integrity in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 275: 38151-9. PMID 10950952 DOI: 10.1074/Jbc.M003432200  1
2000 Sibon OC, Kelkar A, Lemstra W, Theurkauf WE. DNA-replication/DNA-damage-dependent centrosome inactivation in Drosophila embryos. Nature Cell Biology. 2: 90-5. PMID 10655588 DOI: 10.1038/35000041  1
1999 Sibon OC, Laurençon A, Hawley R, Theurkauf WE. The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition. Current Biology : Cb. 9: 302-12. PMID 10209095 DOI: 10.1016/S0960-9822(99)80138-9  1
1999 Theurkauf WE, Heck MM. Identification and characterization of mitotic mutations in Drosophila. Methods in Cell Biology. 61: 317-46. PMID 9891322  1
1998 Theurkauf WE, Hazelrigg TI. In vivo analyses of cytoplasmic transport and cytoskeletal organization during Drosophila oogenesis: characterization of a multi-step anterior localization pathway. Development (Cambridge, England). 125: 3655-66. PMID 9716531  1
1997 Theurkauf WE. Oocyte differentiation: a motor makes a difference. Current Biology : Cb. 7: R548-51. PMID 9285699  1
1997 Sibon OC, Stevenson VA, Theurkauf WE. DNA-replication checkpoint control at the Drosophila midblastula transition. Nature. 388: 93-7. PMID 9214509 DOI: 10.1038/40439  1
1996 Matthies HJ, McDonald HB, Goldstein LS, Theurkauf WE. Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein. The Journal of Cell Biology. 134: 455-64. PMID 8707829 DOI: 10.1083/jcb.134.2.455  1
1996 Lieberfarb ME, Chu T, Wreden C, Theurkauf W, Gergen JP, Strickland S. Mutations that perturb poly(A)-dependent maternal mRNA activation block the initiation of development. Development (Cambridge, England). 122: 579-88. PMID 8625809  1
1995 Sullivan W, Theurkauf WE. The cytoskeleton and morphogenesis of the early Drosophila embryo. Current Opinion in Cell Biology. 7: 18-22. PMID 7755985 DOI: 10.1016/0955-0674(95)80040-9  1
1994 Theurkauf WE. Premature microtubule-dependent cytoplasmic streaming in cappuccino and spire mutant oocytes. Science (New York, N.Y.). 265: 2093-6. PMID 8091233  1
1994 Theurkauf WE. Microtubules and cytoplasm organization during Drosophila oogenesis. Developmental Biology. 165: 352-60. PMID 7958405 DOI: 10.1006/dbio.1994.1258  1
1994 Cooley L, Theurkauf WE. Cytoskeletal functions during Drosophila oogenesis. Science (New York, N.Y.). 266: 590-6. PMID 7939713 DOI: 10.1126/Science.7939713  1
1994 Theurkauf WE. Actin cytoskeleton. Through the bottleneck. Current Biology : Cb. 4: 76-8. PMID 7922320 DOI: 10.1016/S0960-9822(00)00019-1  1
1994 Theurkauf WE. Immunofluorescence analysis of the cytoskeleton during oogenesis and early embryogenesis. Methods in Cell Biology. 44: 489-505. PMID 7707968  0.01
1994 Theurkauf WE. Chapter 25 Immunofluorescence Analysis of the Cytoskeleton during Oogenesis and Early Embryogenesis Methods in Cell Biology. 44: 489-505. DOI: 10.1016/S0091-679X(08)60928-0  1
1993 McKim KS, Jang JK, Theurkauf WE, Hawley RS. Mechanical basis of meiotic metaphase arrest. Nature. 362: 364-6. PMID 8455723 DOI: 10.1038/362364a0  1
1993 Baker J, Theurkauf WE, Schubiger G. Dynamic changes in microtubule configuration correlate with nuclear migration in the preblastoderm Drosophila embryo. The Journal of Cell Biology. 122: 113-21. PMID 8314839 DOI: 10.1083/Jcb.122.1.113  1
1993 Sullivan W, Fogarty P, Theurkauf W. Mutations affecting the cytoskeletal organization of syncytial Drosophila embryos. Development (Cambridge, England). 118: 1245-54. PMID 8269851  1
1993 Theurkauf WE, Alberts BM, Jan YN, Jongens TA. A central role for microtubules in the differentiation of Drosophila oocytes. Development (Cambridge, England). 118: 1169-80. PMID 8269846  1
1993 Hawley RS, Theurkauf WE. Requiem for distributive segregation: achiasmate segregation in Drosophila females. Trends in Genetics : Tig. 9: 310-7. PMID 8236460 DOI: 10.1016/0168-9525(93)90249-H  1
1993 Theurkauf W. Laser scanning confocal microscopic analysis of cytoskeletal and nuclear reorganization in live Drosophila embryos Proceedings - Annual Meeting, Microscopy Society of America. 174-175.  1
1992 Theurkauf WE, Hawley RS. Meiotic spindle assembly in Drosophila females: behavior of nonexchange chromosomes and the effects of mutations in the nod kinesin-like protein. The Journal of Cell Biology. 116: 1167-80. PMID 1740471  1
1992 Theurkauf WE, Smiley S, Wong ML, Alberts BM. Reorganization of the cytoskeleton during Drosophila oogenesis: implications for axis specification and intercellular transport. Development (Cambridge, England). 115: 923-36. PMID 1451668  1
1992 Theurkauf WE. Behavior of structurally divergent alpha-tubulin isotypes during Drosophila embryogenesis: evidence for post-translational regulation of isotype abundance. Developmental Biology. 154: 205-17. PMID 1426627 DOI: 10.1016/0012-1606(92)90060-T  1
1991 Kellogg DR, Sullivan W, Theurkauf W, Oegema K, Raff JW, Alberts BM. Studies on the centrosome and cytoplasmic organization in the early Drosophila embryo. Cold Spring Harbor Symposia On Quantitative Biology. 56: 649-62. PMID 1840267 DOI: 10.1101/Sqb.1991.056.01.074  1
1986 Theurkauf WE, Baum H, Bo J, Wensink PC. Tissue-specific and constitutive alpha-tubulin genes of Drosophila melanogaster code for structurally distinct proteins. Proceedings of the National Academy of Sciences of the United States of America. 83: 8477-81. PMID 3095837 DOI: 10.1073/Pnas.83.22.8477  1
1984 De Camilli P, Miller PE, Navone F, Theurkauf WE, Vallee RB. Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence. Neuroscience. 11: 817-46. PMID 6377119 DOI: 10.1016/0306-4522(84)90194-5  1
1984 Vallee RB, Bloom GS, Theurkauf WE. Microtubule-associated proteins: subunits of the cytomatrix. The Journal of Cell Biology. 99: 38s-44s. PMID 6086669  1
1983 Theurkauf WE, Vallee RB. Extensive cAMP-dependent and cAMP-independent phosphorylation of microtubule-associated protein 2. The Journal of Biological Chemistry. 258: 7883-6. PMID 6305960  1
1982 Miller P, Walter U, Theurkauf WE, Vallee RB, De Camilli P. Frozen tissue sections as an experimental system to reveal specific binding sites for the regulatory subunit of type II cAMP-dependent protein kinase in neurons. Proceedings of the National Academy of Sciences of the United States of America. 79: 5562-6. PMID 6291051 DOI: 10.1073/pnas.79.18.5562  1
1982 Theurkauf WE, Vallee RB. Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2. The Journal of Biological Chemistry. 257: 3284-90. PMID 6277931  1
1981 Vallee RB, DiBartolomeis MJ, Theurkauf WE. A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2). The Journal of Cell Biology. 90: 568-76. PMID 6270156 DOI: 10.1083/Jcb.90.3.568  1
Show low-probability matches.