Sebastiaan Engelborghs, Ph.D. - Publications

Affiliations: 
2004 Universiteit Antwerpen (Belgium) 
Area:
Neuroscience Biology, Mental Health

323 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hirschberg Y, Valle-Tamayo N, Dols-Icardo O, Engelborghs S, Buelens B, Vandenbroucke RE, Vermeiren Y, Boonen K, Mertens I. Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia. Journal of Extracellular Vesicles. 12: e12383. PMID 38082559 DOI: 10.1002/jev2.12383  0.374
2023 Bosmans J, Gommeren H, Zu Eulenburg P, Gilles A, Mertens G, Van Ombergen A, Cras P, Engelborghs S, Van Rompaey V. Is vestibular function related to human hippocampal volume? Journal of Vestibular Research : Equilibrium & Orientation. PMID 37927291 DOI: 10.3233/VES-230076  0.3
2023 Richter AL, Diepeveen-de Bruin M, Balvers MGJ, De Groot LCPGM, De Deyn PP, Engelborghs S, Witkamp RF, Vermeiren Y. Association between low vitamin D status, serotonin and clinico-bio-behavioral parameters in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. PMID 37806302 DOI: 10.1159/000534492  0.317
2023 Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, et al. Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning. Genome Medicine. 15: 79. PMID 37794492 DOI: 10.1186/s13073-023-01233-z  0.335
2023 Del Campo M, Vermunt L, Peeters CFW, Sieben A, Hok-A-Hin YS, Lleó A, Alcolea D, van Nee M, Engelborghs S, van Alphen JL, Arezoumandan S, Chen-Plotkin A, Irwin DJ, van der Flier WM, Lemstra AW, et al. CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease. Nature Communications. 14: 5635. PMID 37704597 DOI: 10.1038/s41467-023-41122-y  0.362
2023 Bosmans J, Gommeren H, Gilles A, Mertens G, Van Ombergen A, Cras P, Engelborghs S, Vereeck L, Lammers MJW, Van Rompaey V. Evidence of Vestibular and Balance Dysfunction in Patients With Mild Cognitive Impairment and Alzheimer's Disease. Ear and Hearing. PMID 37482637 DOI: 10.1097/AUD.0000000000001401  0.396
2023 Shi L, Xu J, Green R, Wretlind A, Homann J, Buckley NJ, Tijms BM, Vos SJB, Lill CM, Kate MT, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, et al. Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36790009 DOI: 10.1002/alz.12961  0.397
2022 Küçükali F, Neumann A, Van Dongen J, De Pooter T, Joris G, De Rijk P, Ohlei O, Dobricic V, Bos I, Vos SJB, Engelborghs S, De Roeck E, Vandenberghe R, Gabel S, Meersmans K, et al. Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36464806 DOI: 10.1002/alz.12842  0.35
2022 Laton J, Van Schependom J, Goossens J, Wiels W, Sieben A, De Deyn PP, Goeman J, Streffer J, van der Zee J, Martin JJ, Van Broeckhoven C, De Vos M, Bjerke M, Nagels G, Engelborghs S. Improved Alzheimer's Disease versus Frontotemporal Lobar Degeneration Differential Diagnosis Combining EEG and Neurochemical Biomarkers: A Pilot Study. Journal of Alzheimer's Disease : Jad. 90: 1739-1747. PMID 36336933 DOI: 10.3233/JAD-220693  0.377
2022 Gossye H, Van Mossevelde S, Sieben A, Bjerke M, Van de Craen EH, van der Zee J, De Deyn PP, De Bleecker J, Versijpt J, van den Ende J, Deryck O, Bourgeois P, Bier JC, Goethals M, Vandenberghe R, ... Engelborghs S, et al. Patients carrying the mutation p.R406W in MAPT present with non-conforming phenotypic spectrum. Brain : a Journal of Neurology. PMID 36171642 DOI: 10.1093/brain/awac362  0.429
2022 Jansen IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, Dalmasso MC, Grenier-Boley B, Zettergren A, Mishra A, Ali M, Andrade V, Bellenguez C, Kleineidam L, Küçükali F, Sung YJ, Tesí N, ... ... Engelborghs S, et al. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathologica. PMID 36066633 DOI: 10.1007/s00401-022-02454-z  0.374
2022 Meulemans C, Leijten M, Van Waes L, Engelborghs S, De Maeyer S. Cognitive Writing Process Characteristics in Alzheimer's Disease. Frontiers in Psychology. 13: 872280. PMID 35899013 DOI: 10.3389/fpsyg.2022.872280  0.311
2022 Vromen EM, de Boer SCM, Teunissen CE, Rozemuller A, Sieben A, Bjerke M, Visser PJ, Bouwman FH, Engelborghs S, Tijms BM. Biomarker A+T-: is this Alzheimer's disease or not? A combined CSF and pathology study. Brain : a Journal of Neurology. PMID 35511164 DOI: 10.1093/brain/awac158  0.392
2022 Bouwman FH, Frisoni GB, Johnson SC, Chen X, Engelborghs S, Ikeuchi T, Paquet C, Ritchie C, Bozeat S, Quevenco FC, Teunissen C. Clinical application of CSF biomarkers for Alzheimer's disease: From rationale to ratios. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12314. PMID 35496374 DOI: 10.1002/dad2.12314  0.407
2022 Homann J, Osburg T, Ohlei O, Dobricic V, Deecke L, Bos I, Vandenberghe R, Gabel S, Scheltens P, Teunissen CE, Engelborghs S, Frisoni G, Blin O, Richardson JC, Bordet R, et al. Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset. Frontiers in Aging Neuroscience. 14: 840651. PMID 35386118 DOI: 10.3389/fnagi.2022.840651  0.338
2022 Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... Engelborghs S, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z  0.378
2022 Visser PJ, Reus LM, Gobom J, Jansen I, Dicks E, van der Lee SJ, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuevo JL, Engelborghs S, Freund-Levi Y, et al. Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. Molecular Neurodegeneration. 17: 27. PMID 35346299 DOI: 10.1186/s13024-022-00521-3  0.313
2022 Bridel C, Somers C, Sieben A, Rozemuller A, Niemantsverdriet E, Struyfs H, Vermeiren Y, Van Broeckhoven C, De Deyn PP, Bjerke M, Nagels G, Teunissen CE, Engelborghs S. Associating Alzheimer's disease pathology with its cerebrospinal fluid biomarkers. Brain : a Journal of Neurology. PMID 35026840 DOI: 10.1093/brain/awac013  0.383
2021 Delaby C, Teunissen CE, Blennow K, Alcolea D, Arisi I, Amar EB, Beaume A, Bedel A, Bellomo G, Bigot-Corbel E, Bjerke M, Blanc-Quintin MC, Boada M, Bousiges O, Chapman MD, ... ... Engelborghs S, et al. Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34936194 DOI: 10.1002/alz.12545  0.34
2021 Gommeren H, Bosmans J, Cardon E, Mertens G, Cras P, Engelborghs S, Van Ombergen A, Gilles A, Lammers M, Van Rompaey V. Cortical Auditory Evoked Potentials in Cognitive Impairment and Their Relevance to Hearing Loss: A Systematic Review Highlighting the Evidence Gap. Frontiers in Neuroscience. 15: 781322. PMID 34867176 DOI: 10.3389/fnins.2021.781322  0.301
2021 Xu J, Green R, Kim M, Lord J, Ebshiana A, Westwood S, Baird AL, Nevado-Holgado AJ, Shi L, Hye A, Snowden SG, Bos I, Vos SJB, Vandenberghe R, Teunissen CE, ... ... Engelborghs S, et al. Sex-Specific Metabolic Pathways Were Associated with Alzheimer's Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Cohort. Biomedicines. 9. PMID 34829839 DOI: 10.3390/biomedicines9111610  0.31
2021 Willemse EAJ, Sieben A, Somers C, Vermeiren Y, De Roeck N, Timmers M, Van Broeckhoven C, De Vil B, Cras P, De Deyn PP, Martin JJ, Teunissen CE, Engelborghs S, Bjerke M. Neurogranin as biomarker in CSF is non-specific to Alzheimer's disease dementia. Neurobiology of Aging. 108: 99-109. PMID 34551375 DOI: 10.1016/j.neurobiolaging.2021.08.002  0.348
2021 Wiels WA, Wittens MMJ, Zeeuws D, Baeken C, Engelborghs S. Neuropsychiatric Symptoms in Mild Cognitive Impairment and Dementia Due to AD: Relation With Disease Stage and Cognitive Deficits. Frontiers in Psychiatry. 12: 707580. PMID 34483998 DOI: 10.3389/fpsyt.2021.707580  0.427
2021 Tijms BM, Gobom J, Teunissen C, Dobricic V, Tsolaki M, Verhey F, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuévo JL, Engelborghs S, Freund-Levi Y, Froelich L, Bertram L, et al. CSF Proteomic Alzheimer's Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals. Proteomes. 9. PMID 34449748 DOI: 10.3390/proteomes9030036  0.37
2021 Shi L, Buckley NJ, Bos I, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lléo A, Popp J, Martinez-Lage P, Legido-Quigley C, Barkhof F, Zetterberg H, Visser PJ, Bertram L, et al. Plasma Proteomic Biomarkers Relating to Alzheimer's Disease: A Meta-Analysis Based on Our Own Studies. Frontiers in Aging Neuroscience. 13: 712545. PMID 34366831 DOI: 10.3389/fnagi.2021.712545  0.38
2021 Nous A, Wittens MMJ, Vermeiren Y, De Deyn PP, Van Broeckhoven C, Nagels G, Smolders I, Engelborghs S. Serum Daytime Melatonin Levels Reflect Cerebrospinal Fluid Melatonin Levels in Alzheimer's Disease but Are Not Correlated with Cognitive Decline. Journal of Alzheimer's Disease : Jad. PMID 34366353 DOI: 10.3233/JAD-210562  0.334
2021 Wittens MMJ, Sima DM, Houbrechts R, Ribbens A, Niemantsverdriet E, Fransen E, Bastin C, Benoit F, Bergmans B, Bier JC, De Deyn PP, Deryck O, Hanseeuw B, Ivanoiu A, Lemper JC, ... ... Engelborghs S, et al. Diagnostic Performance of Automated MRI Volumetry by icobrain dm for Alzheimer's Disease in a Clinical Setting: A REMEMBER Study. Journal of Alzheimer's Disease : Jad. PMID 34334402 DOI: 10.3233/JAD-210450  0.366
2021 Hong S, Dobricic V, Ohlei O, Bos I, Vos SJB, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Gabel S, Scheltens P, Teunissen CE, Engelborghs S, Frisoni G, et al. TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33991015 DOI: 10.1002/alz.12330  0.303
2021 Bosmans J, Jorissen C, Gilles A, Mertens G, Engelborghs S, Cras P, Van Ombergen A, Van Rompaey V. Vestibular Function in Older Adults With Cognitive Impairment: A Systematic Review. Ear and Hearing. PMID 33974775 DOI: 10.1097/AUD.0000000000001040  0.403
2021 Shi L, Winchester LM, Westwood S, Baird AL, Anand SN, Buckley NJ, Hye A, Ashton NJ, Bos I, Vos SJB, Kate MT, Scheltens P, Teunissen CE, Vandenberghe R, Gabel S, ... ... Engelborghs S, et al. Replication study of plasma proteins relating to Alzheimer's pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33792144 DOI: 10.1002/alz.12322  0.336
2021 Sieben A, Van Langenhove T, Vermeiren Y, Gossye H, Praet M, Vanhauwaert D, Cousaert C, Engelborghs S, Raedt R, Boon P, Santens P, De Deyn PP, Bracke KR, De Meulemeester K, Van Broeckhoven C, et al. Hippocampal Sclerosis in Frontotemporal Dementia: When Vascular Pathology Meets Neurodegeneration. Journal of Neuropathology and Experimental Neurology. PMID 33638350 DOI: 10.1093/jnen/nlab010  0.319
2021 Nous A, Engelborghs S, Smolders I. Melatonin levels in the Alzheimer's disease continuum: a systematic review. Alzheimer's Research & Therapy. 13: 52. PMID 33622399 DOI: 10.1186/s13195-021-00788-6  0.302
2020 Tijms BM, Gobom J, Reus L, Jansen I, Hong S, Dobricic V, Kilpert F, Ten Kate M, Barkhof F, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, ... ... Engelborghs S, et al. Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics. Brain : a Journal of Neurology. 143: 3776-3792. PMID 33439986 DOI: 10.1093/brain/awaa325  0.413
2020 Frederiksen KS, Nielsen TR, Winblad B, Schmidt R, Kramberger MG, Jones RW, Hort J, Grimmer T, Georges J, Frölich L, Engelborghs S, Dubois B, Waldemar G. European Academy of Neurology/European Alzheimer's Disease Consortium position statement on diagnostic disclosure, biomarker counseling, and management of patients with mild cognitive impairment. European Journal of Neurology. PMID 33368924 DOI: 10.1111/ene.14668  0.329
2020 Hong S, Prokopenko D, Dobricic V, Kilpert F, Bos I, Vos SJB, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Cleynen I, Gabel S, Schaeverbeke J, Scheltens P, Teunissen CE, ... ... Engelborghs S, et al. Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset. Translational Psychiatry. 10: 403. PMID 33223526 DOI: 10.1038/s41398-020-01074-z  0.358
2020 Bosmans J, Jorissen C, Cras P, Van Ombergen A, Engelborghs S, Gilles A, Princen E, Moyaert J, Mertens G, Van Rompaey V. Impact of hearing loss and vestibular decline on cognition in Alzheimer's disease: a prospective longitudinal study protocol (Gehoor, Evenwicht en Cognitie, GECkO). Bmj Open. 10: e039601. PMID 32948575 DOI: 10.1136/Bmjopen-2020-039601  0.464
2020 Bosmans J, Jorissen C, Cras P, Van Ombergen A, Engelborghs S, Gilles A, Princen E, Moyaert J, Mertens G, Van Rompaey V. Impact of hearing loss and vestibular decline on cognition in Alzheimer's disease: a prospective longitudinal study protocol (Gehoor, Evenwicht en Cognitie, GECkO). Bmj Open. 10: e039601. PMID 32948575 DOI: 10.1136/bmjopen-2020-039601  0.359
2020 Ivanoiu A, Engelborghs S, Hanseeuw B. [Early diagnosis of Alzheimer's disease (with the announcement of the diagnosis)]. La Revue Du Praticien. 70: 158-163. PMID 32877127  0.32
2020 Shi L, Winchester LM, Liu BY, Killick R, Ribe EM, Westwood S, Baird AL, Buckley NJ, Hong S, Dobricic V, Kilpert F, Franke A, Kiddle S, Sattlecker M, Dobson R, ... ... Engelborghs S, et al. Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology. Journal of Alzheimer's Disease : Jad. PMID 32831200 DOI: 10.3233/Jad-200208  0.423
2020 Saddiki H, Fayosse A, Cognat E, Sabia S, Engelborghs S, Wallon D, Alexopoulos P, Blennow K, Zetterberg H, Parnetti L, Zerr I, Hermann P, Gabelle A, Boada M, Orellana A, et al. Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. Plos Medicine. 17: e1003289. PMID 32817639 DOI: 10.1371/journal.pmed.1003289  0.372
2020 Mormont E, Bier JC, Bruffaerts R, Cras P, De Deyn P, Deryck O, Engelborghs S, Petrovic M, Picard G, Segers K, Thiery E, Versijpt J, Hanseeuw B. Practices and opinions about disclosure of the diagnosis of Alzheimer's disease to patients with MCI or dementia: a survey among Belgian medical experts in the field of dementia. Acta Neurologica Belgica. PMID 32715405 DOI: 10.1007/S13760-020-01448-6  0.412
2020 Novak G, Streffer JR, Timmers M, Henley D, Brashear HR, Bogert J, Russu A, Janssens L, Tesseur I, Tritsmans L, Van Nueten L, Engelborghs S. Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer's disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study. Alzheimer's Research & Therapy. 12: 58. PMID 32410694 DOI: 10.1186/s13195-020-00614-5  0.316
2020 Verelst J, Geukens N, Eddarkaoui S, Vliegen D, De Smidt E, Rosseels J, Franssens V, Molenberghs S, Francois C, Stoops E, Bjerke M, Engelborghs S, Laghmouchi M, Carmans S, Buée L, et al. A Novel Tau Antibody Detecting the First Amino-Terminal Insert Reveals Conformational Differences Among Tau Isoforms. Frontiers in Molecular Biosciences. 7: 48. PMID 32296712 DOI: 10.3389/Fmolb.2020.00048  0.308
2020 Van Rickstal R, De Vleminck A, Morrison SR, Koopmans RT, van der Steen JT, Engelborghs S, Neugroschl J, Aldridge MD, Sano M, Van den Block L. Comparing Advance Care Planning in Young-Onset Dementia in the USA vs Belgium: Challenges Partly Related to Societal Context. Journal of the American Medical Directors Association. PMID 32173310 DOI: 10.1016/J.Jamda.2020.01.007  0.353
2020 Westwood S, Baird AL, Anand SN, Nevado-Holgado AJ, Kormilitzin A, Shi L, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Baker S, Buckley NJ, Ten Kate M, Scheltens P, ... ... Engelborghs S, et al. Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort. Journal of Alzheimer's Disease : Jad. PMID 31985466 DOI: 10.3233/Jad-190434  0.35
2019 Stamate D, Kim M, Proitsi P, Westwood S, Baird A, Nevado-Holgado A, Hye A, Bos I, Vos SJB, Vandenberghe R, Teunissen CE, Kate MT, Scheltens P, Gabel S, Meersmans K, ... ... Engelborghs S, et al. A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort. Alzheimer's & Dementia (New York, N. Y.). 5: 933-938. PMID 31890857 DOI: 10.1016/J.Trci.2019.11.001  0.303
2019 Shi L, Westwood S, Baird AL, Winchester L, Dobricic V, Kilpert F, Hong S, Franke A, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Buckley NJ, Kate MT, ... ... Engelborghs S, et al. Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31495601 DOI: 10.1016/J.Jalz.2019.06.4951  0.339
2019 Gossye H, Van Broeckhoven C, Engelborghs S. The Use of Biomarkers and Genetic Screening to Diagnose Frontotemporal Dementia: Evidence and Clinical Implications. Frontiers in Neuroscience. 13: 757. PMID 31447625 DOI: 10.3389/fnins.2019.00757  0.38
2019 De Roeck EE, van der Vorst A, Engelborghs S, Zijlstra GAR, Dierckx E. Exploring Cognitive Frailty: Prevalence and Associations with Other Frailty Domains in Older People with Different Degrees of Cognitive Impairment. Gerontology. 1-10. PMID 31330515 DOI: 10.1159/000501168  0.339
2019 Picard G, Bier JC, Capron I, De Deyn PP, Deryck O, Engelborghs S, Hanseeuw B, Lemper JC, Mormont E, Petrovic M, Salmon E, Segers K, Sieben A, Thiery E, Ventura M, et al. Dementia, End of Life, and Euthanasia: A Survey Among Dementia Specialists Organized by the Belgian Dementia Council. Journal of Alzheimer's Disease : Jad. PMID 31127774 DOI: 10.3233/JAD-181277  0.317
2019 Kim M, Snowden S, Suvitaival T, Ali A, Merkler DJ, Ahmad T, Westwood S, Baird A, Proitsi P, Nevado-Holgado A, Hye A, Bos I, Vos S, Vandenberghe R, Teunissen C, ... ... Engelborghs S, et al. Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31078433 DOI: 10.1016/J.Jalz.2019.03.004  0.463
2019 Timmers M, Tesseur I, Bogert J, Zetterberg H, Blennow K, Börjesson-Hanson A, Baquero M, Boada M, Randolph C, Tritsmans L, Van Nueten L, Engelborghs S, Streffer JR. Relevance of the interplay between amyloid and tau for cognitive impairment in early Alzheimer's disease. Neurobiology of Aging. 79: 131-141. PMID 31055223 DOI: 10.1016/j.neurobiolaging.2019.03.016  0.394
2019 Morgan AR, Touchard S, Leckey C, O'Hagan C, Nevado-Holgado AJ, Barkhof F, Bertram L, Blin O, Bos I, Dobricic V, Engelborghs S, Frisoni G, Frölich L, Gabel S, et al. Inflammatory biomarkers in Alzheimer's disease plasma. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31047856 DOI: 10.1016/J.Jalz.2019.03.007  0.414
2019 Ottoy J, Niemantsverdriet E, Verhaeghe J, De Roeck E, Struyfs H, Somers C, Wyffels L, Ceyssens S, Van Mossevelde S, Van den Bossche T, Van Broeckhoven C, Ribbens A, Bjerke M, Stroobants S, Engelborghs S, et al. Association of short-term cognitive decline and MCI-to-AD dementia conversion with CSF, MRI, amyloid- and F-FDG-PET imaging. Neuroimage. Clinical. 22: 101771. PMID 30927601 DOI: 10.1016/J.Nicl.2019.101771  0.486
2019 Somers C, Lewczuk P, Sieben A, Van Broeckhoven C, De Deyn PP, Kornhuber J, Martin JJ, Bjerke M, Engelborghs S. Validation of the Erlangen Score Algorithm for Differential Dementia Diagnosis in Autopsy-Confirmed Subjects. Journal of Alzheimer's Disease : Jad. PMID 30883344 DOI: 10.3233/Jad-180563  0.401
2019 Bos I, Vos S, Verhey F, Scheltens P, Teunissen C, Engelborghs S, Sleegers K, Frisoni G, Blin O, Richardson JC, Bordet R, Tsolaki M, Popp J, Peyratout G, Martinez-Lage P, et al. Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30853464 DOI: 10.1016/J.Jalz.2019.01.004  0.437
2019 Cacace R, Vos KD, Heeman B, Mossevelde SV, Sieben A, Engelborghs S, Deyn PPD, Martin J, Broeckhoven CV. P1-210: Investigating The Involvement Of The Dpp6-Kv4.2 Protein Complex In Dementia Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.765  0.358
2018 Ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Vandenberghe R, Gabel S, Schaeverbeke J, Scheltens P, Blin O, Richardson JC, Bordet R, Wallin A, Eckerstrom C, Molinuevo JL, ... Engelborghs S, et al. MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study. Alzheimer's Research & Therapy. 10: 100. PMID 30261928 DOI: 10.1186/S13195-018-0428-1  0.474
2018 Timmers M, Streffer JR, Russu A, Tominaga Y, Shimizu H, Shiraishi A, Tatikola K, Smekens P, Börjesson-Hanson A, Andreasen N, Matias-Guiu J, Baquero M, Boada M, Tesseur I, Tritsmans L, ... ... Engelborghs S, et al. Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study. Alzheimer's Research & Therapy. 10: 85. PMID 30134967 DOI: 10.1186/S13195-018-0415-6  0.441
2018 Van Schependom J, Niemantsverdriet E, Smeets D, Engelborghs S. Callosal circularity as an early marker for Alzheimer's disease. Neuroimage. Clinical. 19: 516-526. PMID 29984160 DOI: 10.1016/J.Nicl.2018.05.018  0.435
2018 Bos I, Vos S, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni G, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Baird A, Dobson R, Legido-Quigley C, Sleegers K, et al. The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics. Alzheimer's Research & Therapy. 10: 64. PMID 29980228 DOI: 10.1186/S13195-018-0396-5  0.447
2018 Perrone F, Cacace R, Van Mossevelde S, Van den Bossche T, De Deyn PP, Cras P, Engelborghs S, van der Zee J, Van Broeckhoven C. Genetic screening in early-onset dementia patients with unclear phenotype: relevance for clinical diagnosis. Neurobiology of Aging. PMID 29859640 DOI: 10.1016/J.Neurobiolaging.2018.04.015  0.434
2018 Van Mossevelde S, Engelborghs S, van der Zee J, Van Broeckhoven C. Genotype-phenotype links in frontotemporal lobar degeneration. Nature Reviews. Neurology. PMID 29777184 DOI: 10.1038/S41582-018-0009-8  0.329
2018 De Roeck EE, Dury S, De Witte N, De Donder L, Bjerke M, De Deyn PP, Engelborghs S, Dierckx E. CFAI-Plus: Adding cognitive frailty as a new domain to the comprehensive frailty assessment instrument. International Journal of Geriatric Psychiatry. PMID 29637620 DOI: 10.1002/Gps.4875  0.377
2018 Niemantsverdriet E, Feyen BFE, Le Bastard N, Martin JJ, Goeman J, De Deyn PP, Bjerke M, Engelborghs S. Added Diagnostic Value of Cerebrospinal Fluid Biomarkers for Differential Dementia Diagnosis in an Autopsy-Confirmed Cohort. Journal of Alzheimer's Disease : Jad. PMID 29614653 DOI: 10.3233/Jad-170927  0.43
2018 Mattsson N, Groot C, Jansen WJ, Landau S, Villemagne V, Engelborghs S, Mintun M, Lleo A, Molinuevo JL, Jagust W, Frisoni GB, Ivanoiu A, Chételat G, Resende de Oliveira C, Rodrigue KM, et al. Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29601787 DOI: 10.1016/J.Jalz.2018.02.009  0.321
2018 De Roeck A, Duchateau L, Van Dongen J, Cacace R, Bjerke M, Van den Bossche T, Cras P, Vandenberghe R, De Deyn PP, Engelborghs S, Van Broeckhoven C, Sleegers K. An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer's disease. Acta Neuropathologica. PMID 29589097 DOI: 10.1007/S00401-018-1841-Z  0.425
2018 Bjerke M, Engelborghs S. Cerebrospinal Fluid Biomarkers for Early and Differential Alzheimer's Disease Diagnosis. Journal of Alzheimer's Disease : Jad. 62: 1199-1209. PMID 29562530 DOI: 10.3233/Jad-170680  0.471
2018 Goossens J, Bjerke M, Van Mossevelde S, Van den Bossche T, Goeman J, De Vil B, Sieben A, Martin JJ, Cras P, De Deyn PP, Van Broeckhoven C, van der Zee J, Engelborghs S. Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration. Alzheimer's Research & Therapy. 10: 31. PMID 29559004 DOI: 10.1186/S13195-018-0364-0  0.449
2018 Janssens J, Vermeiren Y, Fransen E, Aerts T, Van Dam D, Engelborghs S, De Deyn PP. Cerebrospinal fluid and serum MHPG improve Alzheimer's disease versus dementia with Lewy bodies differential diagnosis. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 172-181. PMID 29552632 DOI: 10.1016/J.Dadm.2018.01.002  0.51
2018 Teunissen CE, Otto M, Engelborghs S, Herukka SK, Lehmann S, Lewczuk P, Lleó A, Perret-Liaudet A, Tumani H, Turner MR, Verbeek MM, Wiltfang J, Zetterberg H, Parnetti L, Blennow K. White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation. Alzheimer's Research & Therapy. 10: 30. PMID 29544527 DOI: 10.1186/S13195-018-0359-X  0.336
2018 Willemse EAJ, De Vos A, Herries EM, Andreasson U, Engelborghs S, van der Flier WM, Scheltens P, Crimmins D, Ladenson JH, Vanmechelen E, Zetterberg H, Fagan AM, Blennow K, Bjerke M, Teunissen CE. Neurogranin as Cerebrospinal Fluid Biomarker for Alzheimer Disease: An Assay Comparison Study. Clinical Chemistry. PMID 29523639 DOI: 10.1373/Clinchem.2017.283028  0.494
2018 Vloeberghs R, Opmeer EM, De Deyn PP, Engelborghs S, De Roeck EE. [Apathy, depression and cognitive functioning in patients with MCI and dementia]. Tijdschrift Voor Gerontologie En Geriatrie. PMID 29488192 DOI: 10.1007/S12439-018-0248-6  0.39
2018 Willemse EAJ, Sieben A, Somers C, Vermeiren Y, Roeck ND, Luyckx J, Broeckhoven CV, Vil BD, Cras P, Deyn PPD, Martin J, Teunissen CE, Engelborghs S, Bjerke M. P4-270: Neurogranin In Cerebrospinal Fluid Is Not Specific To Alzheimer'S Disease Dementia Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.092  0.494
2018 Willemse EAJ, Vermeiren Y, García-Ayllón M, Bridel C, Deyn PPD, Engelborghs S, Flier WMVd, Janssen E, Font IL, Manadas B, Mendes VM, Roeck ND, Sáez-Valero J, Struys EA, Uffelen KWv, et al. P2-228: Pre-Analytical Stability Of Novel Cerebrospinal Fluid Biomarkers For Dementia Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.915  0.388
2018 Roeck AD, Duchateau L, Dongen JV, Cacace R, Bjerke M, Bossche TVd, Cras P, Vandenberghe R, Deyn PPD, Engelborghs S, Broeckhoven CV, Sleegers K. O4-01-01: In-Depth Analysis Of An Abca7 Vntr In Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2909  0.373
2018 Hong S, Dobricic V, Smith RG, Küçükali F, Kilpert F, Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Tsolaki M, et al. F1-02-04: Genomics And Epigenomics Analyses In The Emif-Ad Multimodal Biomarker Discovery Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2310  0.322
2018 Bos I, Vos SJB, Verhey FRJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Tsolaki M, Popp J, Martinez-Lage P, Lleó A, Johannsen P, Freund-Levi Y, et al. F1-02-01: RELATING CSF MARKERS NEUROGRANIN, NEUROFILAMENT-LIGHT AND YKL-40 TO Aβ, APOE ε4 AND COGNITION: RESULTS FROM THE EMIF-AD MULTIMODAL BIOMARKER DISCOVERY STUDY Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2307  0.431
2018 Kim M, Snowden SG, Ahmad T, Westwood S, Baird AL, Proitsi P, Nevado-Holgado AJ, Hye A, Ashton NJ, Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, et al. P3-233: PLASMA PRIMARY FATTY AMIDES ASSOCIATE TO CSF AMYLOID LEVELS AND ALZHEIMER\textquotesingleS DISEASE PROGRESSION IN THE EMIF-AD BIOMARKER DISCOVERY COHORT Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1592  0.456
2018 Cacace R, Hoogmartens J, Mossevelde SV, Bossche TVd, Geerts N, Vandenberghe R, Deyn PPD, Zee Jvd, Engelborghs S, Sleegers K, Broeckhoven CV. P3-128: Exploring The Molecular Mechanism Of Neuronal Hyperexcitability In Dementia Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1485  0.324
2017 Ottoy J, Verhaeghe J, Niemantsverdriet E, Engelborghs S, Stroobants S, Staelens S. A simulation study on the impact of the blood flow-dependent component in [18F]AV45 SUVR in Alzheimer's disease. Plos One. 12: e0189155. PMID 29211812 DOI: 10.1371/Journal.Pone.0189155  0.355
2017 Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, et al. Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia. Jama Psychiatry. PMID 29188296 DOI: 10.1001/Jamapsychiatry.2017.3391  0.466
2017 Lewczuk P, Riederer P, O'Bryant SE, Verbeek MM, Dubois B, Visser PJ, Jellinger KA, Engelborghs S, Ramirez A, Parnetti L, Jack CR, Teunissen CE, Hampel H, Lleó A, Jessen F, et al. Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-85. PMID 29076399 DOI: 10.1080/15622975.2017.1375556  0.319
2017 Versijpt J, Tant M, Beyer I, Bier JC, Cras P, De Deyn PP, De Wit P, Deryck O, Hanseeuw B, Lambert M, Lemper JC, Mormont E, Petrovic M, Picard G, Salmon E, ... ... Engelborghs S, et al. Alzheimer's disease and driving: review of the literature and consensus guideline from Belgian dementia experts and the Belgian road safety institute endorsed by the Belgian Medical Association. Acta Neurologica Belgica. PMID 28983881 DOI: 10.1007/S13760-017-0840-5  0.354
2017 Niemantsverdriet E, Ottoy J, Somers C, De Roeck E, Struyfs H, Soetewey F, Verhaeghe J, Van den Bossche T, Van Mossevelde S, Goeman J, De Deyn PP, Mariën P, Versijpt J, Sleegers K, Van Broeckhoven C, ... ... Engelborghs S, et al. The Cerebrospinal Fluid Aβ1-42/Aβ1-40 Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer's Disease in a Clinical Setting. Journal of Alzheimer's Disease : Jad. PMID 28869470 DOI: 10.3233/Jad-170327  0.411
2017 Niemantsverdriet E, Valckx S, Bjerke M, Engelborghs S. Alzheimer's disease CSF biomarkers: clinical indications and rational use. Acta Neurologica Belgica. PMID 28752420 DOI: 10.1007/S13760-017-0816-5  0.496
2017 Chiasserini D, Biscetti L, Eusebi P, Salvadori N, Frattini G, Simoni S, De Roeck N, Tambasco N, Stoops E, Vanderstichele H, Engelborghs S, Mollenhauer B, Calabresi P, Parnetti L. Differential role of CSF fatty acid binding protein 3, α-synuclein, and Alzheimer's disease core biomarkers in Lewy body disorders and Alzheimer's dementia. Alzheimer's Research & Therapy. 9: 52. PMID 28750675 DOI: 10.1016/J.Jalz.2017.06.057  0.489
2017 van Waalwijk van Doorn LJC, Kulic L, Koel-Simmelink MJA, Kuiperij HB, Versleijen AAM, Struyfs H, Twaalfhoven HAM, Fourier A, Engelborghs S, Perret-Liaudet A, Lehmann S, Verbeek MM, Vanmechelen EJM, Teunissen CE. Multicenter Analytical Validation of Aβ40 Immunoassays. Frontiers in Neurology. 8: 310. PMID 28725210 DOI: 10.3389/Fneur.2017.00310  0.322
2017 Goossens J, Bjerke M, Struyfs H, Niemantsverdriet E, Somers C, Van den Bossche T, Van Mossevelde S, De Vil B, Sieben A, Martin JJ, Cras P, Goeman J, De Deyn PP, Van Broeckhoven C, van der Zee J, ... Engelborghs S, et al. No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis. Alzheimer's Research & Therapy. 9: 49. PMID 28709448 DOI: 10.1186/S13195-017-0275-5  0.488
2017 Bos I, Vos SJ, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Engelborghs S, Niemantsverdriet E, De Roeck EE, Tsolaki M, Freund-Levi Y, Johannsen P, Vandenberghe R, et al. The frequency and influence of dementia risk factors in prodromal Alzheimer's disease. Neurobiology of Aging. 56: 33-40. PMID 28482212 DOI: 10.1016/J.Neurobiolaging.2017.03.034  0.487
2017 Herukka SK, Simonsen AH, Andreasen N, Baldeiras I, Bjerke M, Blennow K, Engelborghs S, Frisoni GB, Gabryelewicz T, Galluzzi S, Handels R, Kramberger MG, Kulczyńska A, Molinuevo JL, Mroczko B, et al. Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 13: 285-295. PMID 28341066 DOI: 10.1016/J.Jalz.2016.09.009  0.502
2017 Simonsen AH, Herukka SK, Andreasen N, Baldeiras I, Bjerke M, Blennow K, Engelborghs S, Frisoni GB, Gabryelewicz T, Galluzzi S, Handels R, Kramberger MG, Kulczyńska A, Molinuevo JL, Mroczko B, et al. Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 13: 274-284. PMID 28341065 DOI: 10.1016/J.Jalz.2016.09.008  0.48
2017 Ottoy J, Verhaeghe J, Niemantsverdriet E, Wyffels L, Somers C, De Roeck E, Struyfs H, Soetewey F, Deleye S, Van den Bossche T, Van Mossevelde S, Ceyssens S, Versijpt J, Stroobants S, Engelborghs S, et al. Validation of the semi-quantitative static SUVR method for [(18)F]-AV45 PET by pharmacokinetic modeling with an arterial input function. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28336779 DOI: 10.2967/Jnumed.116.184481  0.372
2017 Bosco P, Redolfi A, Bocchetta M, Ferrari C, Mega A, Galluzzi S, Austin M, Chincarini A, Collins DL, Duchesne S, Maréchal B, Roche A, Sensi F, Wolz R, Alegret M, ... ... Engelborghs S, et al. The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer's disease: An EADC study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28263741 DOI: 10.1016/J.Jalz.2017.01.019  0.473
2017 Willemse E, van Uffelen K, Brix B, Engelborghs S, Vanderstichele H, Teunissen C. How to handle adsorption of cerebrospinal fluid amyloid-β (1-42) in laboratory practice? Identifying problematic handlings and resolving the issue by use of the Aβ42/Aβ40 ratio. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28222302 DOI: 10.1016/J.Jalz.2017.01.010  0.32
2017 Timmers M, Barão S, Van Broeck B, Tesseur I, Slemmon J, De Waepenaert K, Bogert J, Shaw LM, Engelborghs S, Moechars D, Mercken M, Van Nueten L, Tritsmans L, de Strooper B, Streffer JR. BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer's Disease Markers in Elderly Healthy Participants. Journal of Alzheimer's Disease : Jad. PMID 28157093 DOI: 10.3233/Jad-160829  0.447
2017 Somers C, Goossens J, Engelborghs S, Bjerke M. Selecting Aβ isoforms for an Alzheimer's disease cerebrospinal fluid biomarker panel. Biomarkers in Medicine. PMID 28111962 DOI: 10.2217/Bmm-2016-0276  0.458
2017 Struyfs H, Pascoal TA, Ng KP, Mathotaarachchi SS, Benedet AL, Kang MS, Shin M, Therriault J, Billiet T, Smeets D, Ribbens A, Gauthier S, Bjerke M, Engelborghs S, Rosa-Neto P. The “A/T/N” System: Added Predictive Value Of N Biomarkers Of Progression From Mci To Dementia Over 2 And 4 Years Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.685  0.412
2017 Willemse EA, Vos AD, Herries EM, Andreasson U, Engelborghs S, Vanmechelen E, Flier WMvd, Scheltens P, Ladenson JH, Zetterberg H, Blennow K, Fagan AM, Bjerke M, Teunissen CE. Clinical Performance Of Neurogranin As A Cerebrospinal Fluid Biomarker For Alzheimer’S Disease: An Assay Comparison Study Alzheimers & Dementia. 13: 199. DOI: 10.1016/J.Jalz.2017.07.061  0.325
2017 Westwood S, Hye A, Lleó A, Nevado-Holgado AJ, Baird AL, Wallin A, Leslie A, Jimenez B, Liu BY, Legido-Quigley C, Dima D, Ruvolo D, Holmes E, D'Hondt E, Westman E, ... ... Engelborghs S, et al. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION Alzheimer's & Dementia. 13: P174-P175. DOI: 10.1016/J.Jalz.2017.07.016  0.436
2017 Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Baird AL, Legido-Quigley C, Bertram L, Barkhof F, et al. European Medical Information Framework For Alzheimer’S Disease (Emif-Ad): The Biomarker Discovery Study Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.864  0.367
2017 Tesseur I, Timmers M, Borjesson A, Broeck BV, Slemmon JR, Smekens P, Aguilar M, Baquero M, Frank A, Matias-Guiu J, Boada M, Hugon J, Prins ND, Laske C, Tritsmans L, ... ... Engelborghs S, et al. AMYLOID-β42 (Aβ42) DIFFERENTIALLY CORRELATES WITH CSF TOTAL AND HYPERPHOSPHORYLATED TAU IN AN AMYLOID-POSITIVE VERSUS AMYLOID-NEGATIVE EARLY PRODROMAL AND ASYMPTOMATIC AT-RISK FOR AD POPULATION Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.863  0.392
2017 Vos SJB, Gronenschild E, Jacobs HIL, Bos I, Scheltens P, Niemantsverdriet E, Engelborghs S, Verhey FRJ, Visser PJ. Characterization Of Suspected Non-Alzheimer’S Disease Pathophysiology (Snap) In Individuals With Mild Cognitive Impairment Using Neuroimaging Alzheimers & Dementia. 13: 414. DOI: 10.1016/J.Jalz.2017.06.403  0.399
2017 Westwood S, Baird AL, Hye A, Bos I, Vos SJ, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Snowden SG, et al. [P1-289]: DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT Alzheimer's & Dementia. 13: P361-P362. DOI: 10.1016/J.Jalz.2017.06.305  0.407
2017 Struyfs H, Pascoal TA, Ng KP, Mathotaarachchi SS, Shin M, Kang MS, Therriault J, Smeets D, Ribbens A, Gauthier S, Bjerke M, Engelborghs S, Rosa-Neto P. Fdg-Pet Power To Predict Memory Decline In Alzheimer’S Disease Depends On Disease Phase And Amyloid And Tau Status Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2107  0.32
2017 Abbott RA, Cormack FK, Engelborghs S, Timmers M, Randolph C, Zavitz K, Streffer J. [P4-158]: PRE-SCREENING FOR EPISODIC MEMORY DEFICITS CAN ENRICH FOR ELIGIBLE SUBJECTS IN EARLY ALZHEIMER's DISEASE CLINICAL TRIALS Alzheimer's & Dementia. 13: P1319-P1320. DOI: 10.1016/J.Jalz.2017.06.2025  0.363
2017 Mossevelde SV, Zee Jvd, Steger C, Verwilligen L, Cras P, Engelborghs S, Broeckhoven CV. The Mapt P.Arg406Trp Is A Founder Mutation In Belgium And Presents With An Alzheimer Disease Dementia-Like Phenotype Alzheimers & Dementia. 13: 1286. DOI: 10.1016/J.Jalz.2017.06.1940  0.455
2017 Perrone F, Cacace R, Mossevelde SV, Bossche TVd, Sieben A, Engelborghs S, Cras P, Deyn PPD, Martin J, Zee Jvd, Broeckhoven CV. A Prospective Neurogenetic Study On Early-Onset Dementia In Patients With Unclear Initial Diagnosis Of Degenerative Dementia Alzheimers & Dementia. 13: 1284. DOI: 10.1016/J.Jalz.2017.06.1934  0.468
2017 Van Waes L, Leijten M, Mariën P, Engelborghs S. Typing competencies in Alzheimer's disease: An exploration of copy tasks Computers in Human Behavior. 73: 311-319. DOI: 10.1016/J.Chb.2017.03.050  0.338
2016 Perrone F, Nguyen HP, Van Mossevelde S, Moisse M, Sieben A, Santens P, De Bleecker J, Vandenbulcke M, Engelborghs S, Baets J, Cras P, Vandenberghe R, De Jonghe P, De Deyn PP, Martin JJ, et al. Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients. Neurobiology of Aging. PMID 28069311 DOI: 10.1016/J.Neurobiolaging.2016.12.008  0.379
2016 Verslegers L, Schotsmans K, Montagna M, Feyen B, De Jong L, Crols R, Engelborghs S. Severe bilateral subdural hematomas as a complication of diagnostic lumbar puncture for possible Alzheimer's disease. Clinical Neurology and Neurosurgery. 152: 95-96. PMID 27978461 DOI: 10.1016/J.Clineuro.2016.12.003  0.432
2016 Dekens DW, Naudé PJ, Engelborghs S, Vermeiren Y, Van Dam D, Oude Voshaar RC, Eisel UL, De Deyn PP. Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer's Disease (AD) Brain Regions: Differential Findings in AD with and without Depression. Journal of Alzheimer's Disease : Jad. PMID 27716662 DOI: 10.3233/Jad-160330  0.42
2016 van der Zee J, Mariën P, Crols R, Van Mossevelde S, Dillen L, Perrone F, Engelborghs S, Verhoeven J, D'aes T, Ceuterick-De Groote C, Sieben A, Versijpt J, Cras P, Martin JJ, Van Broeckhoven C. Mutated CTSF in adult-onset neuronal ceroid lipofuscinosis and FTD. Neurology. Genetics. 2: e102. PMID 27668283 DOI: 10.1212/Nxg.0000000000000102  0.323
2016 Arnerić SP, Batrla-Utermann R, Beckett L, Bittner T, Blennow K, Carter L, Dean R, Engelborghs S, Genius J, Gordon MF, Hitchcock J, Kaplow J, Luthman J, Meibach R, Raunig D, et al. Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: A View of the Regulatory Science Qualification Landscape from the Coalition Against Major Diseases CSF Biomarker Team. Journal of Alzheimer's Disease : Jad. PMID 27662307 DOI: 10.3233/Jad-160573  0.45
2016 Lewczuk P, Lelental N, Lachmann I, Holzer M, Flach K, Brandner S, Engelborghs S, Teunissen CE, Zetterberg H, Molinuevo JL, Mroczko B, Blennow K, Popp J, Parnetti L, Chiasserini D, et al. Non-Phosphorylated Tau as a Potential Biomarker of Alzheimer's Disease: Analytical and Diagnostic Characterization. Journal of Alzheimer's Disease : Jad. PMID 27662295 DOI: 10.3233/Jad-160448  0.408
2016 Goossens J, Laton J, Van Schependom J, Gielen J, Struyfs H, Van Mossevelde S, Van den Bossche T, Goeman J, De Deyn PP, Sieben A, Martin JJ, Van Broeckhoven C, van der Zee J, Engelborghs S, Nagels G. EEG Dominant Frequency Peak Differentiates Between Alzheimer's Disease and Frontotemporal Lobar Degeneration. Journal of Alzheimer's Disease : Jad. PMID 27636837 DOI: 10.1016/J.Jalz.2016.06.656  0.418
2016 Somers C, Struyfs H, Goossens J, Niemantsverdriet E, Luyckx J, De Roeck N, De Roeck E, De Vil B, Cras P, Martin JJ, De Deyn PP, Bjerke M, Engelborghs S. A Decade of Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in Belgium. Journal of Alzheimer's Disease : Jad. 54: 383-95. PMID 27567807 DOI: 10.1016/J.Jalz.2016.06.918  0.506
2016 Crosiers D, Verstraeten A, Wauters E, Engelborghs S, Peeters K, Mattheijssens M, De Deyn PP, Theuns J, Van Broeckhoven C, Cras P. Mutations in glucocerebrosidase are a major genetic risk factor for Parkinson's disease and increase susceptibility to dementia in a Flanders-Belgian cohort. Neuroscience Letters. PMID 27397011 DOI: 10.1016/J.Neulet.2016.07.008  0.343
2016 De Vos A, Struyfs H, Jacobs D, Fransen E, Klewansky T, De Roeck E, Robberecht C, Van Broeckhoven C, Duyckaerts C, Engelborghs S, Vanmechelen E. The Cerebrospinal Fluid Neurogranin/BACE1 Ratio is a Potential Correlate of Cognitive Decline in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27392859 DOI: 10.3233/Jad-160227  0.487
2016 Van Broeck B, Timmers M, Ramael S, Bogert J, Shaw LM, Mercken M, Slemmon J, Van Nueten L, Engelborghs S, Streffer JR. Impact of frequent cerebrospinal fluid sampling on Aβ levels: systematic approach to elucidate influencing factors. Alzheimer's Research & Therapy. 8: 21. PMID 27206648 DOI: 10.1186/S13195-016-0184-Z  0.366
2016 Müller M, Kuiperij HB, Versleijen AA, Chiasserini D, Farotti L, Baschieri F, Parnetti L, Struyfs H, De Roeck N, Luyckx J, Engelborghs S, Claassen JA, Verbeek MM. Validation of microRNAs in Cerebrospinal Fluid as Biomarkers for Different Forms of Dementia in a Multicenter Study. Journal of Alzheimer's Disease : Jad. PMID 27104900 DOI: 10.3233/Jad-160038  0.387
2016 Verheijen J, Van den Bossche T, van der Zee J, Engelborghs S, Sanchez-Valle R, Lladó A, Graff C, Thonberg H, Pastor P, Ortega-Cubero S, Pastor MA, Benussi L, Ghidoni R, Binetti G, Clarimon J, et al. A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer's disease. Acta Neuropathologica. PMID 27026413 DOI: 10.1007/S00401-016-1566-9  0.409
2016 De Roeck EE, Engelborghs S, Dierckx E. Next Generation Brain Health Depends on Early Alzheimer Disease Diagnosis: From a Timely Diagnosis to Future Population Screening. Journal of the American Medical Directors Association. 17: 452-3. PMID 26972349 DOI: 10.1016/J.Jamda.2016.02.015  0.325
2016 Lelental N, Brandner S, Kofanova O, Blennow K, Zetterberg H, Andreasson U, Engelborghs S, Mroczko B, Gabryelewicz T, Teunissen C, Mollenhauer B, Parnetti L, Chiasserini D, Molinuevo JL, Perret-Liaudet A, et al. Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics. Journal of Alzheimer's Disease : Jad. PMID 26967210 DOI: 10.3233/Jad-150883  0.316
2016 Suárez-Calvet M, Kleinberger G, Araque Caballero MÁ, Brendel M, Rominger A, Alcolea D, Fortea J, Lleó A, Blesa R, Gispert JD, Sánchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, ... ... Engelborghs S, et al. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. Embo Molecular Medicine. PMID 26941262 DOI: 10.15252/Emmm.201506123  0.472
2016 Niemantsverdriet E, Goossens J, Struyfs H, Martin JJ, Goeman J, De Deyn PP, Vanderstichele H, Engelborghs S. Diagnostic Impact of Cerebrospinal Fluid Biomarker (Pre-)Analytical Variability in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 51: 97-106. PMID 26836187 DOI: 10.3233/Jad-150953  0.489
2016 De Roeck E, Ponjaert-Kristoffersen I, Bosmans M, De Deyn PP, Engelborghs S, Dierckx E. Are depressive symptoms in mild cognitive impairment predictive of conversion to dementia? International Psychogeriatrics / Ipa. 28: 921-8. PMID 26778529 DOI: 10.1017/S1041610215002409  0.399
2016 van Waalwijk van Doorn LJ, Koel-Simmelink MJ, Haußmann U, Klafki H, Struyfs H, Linning P, Knölker HJ, Twaalfhoven H, Kuiperij HB, Engelborghs S, Scheltens P, Verbeek MM, Vanmechelen E, Wiltfang J, Teunissen CE. Validation of soluble APP assays as diagnostic CSF biomarkers for neurodegenerative diseases. Journal of Neurochemistry. PMID 26748905 DOI: 10.1111/Jnc.13527  0.311
2016 Struyfs H, Vanmechelen E, De Roeck EE, Fransen E, Niemantsverdriet E, Somers C, Goossens J, De Vos A, Herbst V, Van den Bossche T, Van Mossevelde S, Goeman J, de Deyn PP, Bjerke M, Engelborghs S. P4-322: CSF Biomarkers to Predict Rate of Cognitive Decline in Alzheimer’S Disease Alzheimer's & Dementia. 12: P1157-P1157. DOI: 10.1016/J.Jalz.2016.07.066  0.393
2016 Niemantsverdriet E, Van den Bossche T, Van Mossevelde S, Ottoy J, Verhaeghe J, Somers C, De Roeck EE, Struyfs H, Deleye S, Goeman J, Versijpt J, Paul de Deyn P, Mariën P, Wyffels L, Bjerke M, ... ... Engelborghs S, et al. P4-314: Discordance Between Amyloid-PET and CSF Amyloid-β for Diagnosing Alzheimer’S Disease in a Clinical Setting Alzheimer's & Dementia. 12: P1154-P1154. DOI: 10.1016/J.Jalz.2016.07.057  0.37
2016 Goossens J, van der Zee J, Van Mossevelde S, Vanmechelen E, Van den Bossche T, De Vil B, Sieben A, Martin J, Cras P, Goeman J, de Deyn PP, Van Broeckhoven C, Engelborghs S. P1-176: CSF Exploratory Biomarker Study for (DIFFERENTIAL) Diagnosis of Frontotemporal Lobar Degeneration Alzheimer's & Dementia. 12: P471-P471. DOI: 10.1016/J.Jalz.2016.06.924  0.349
2016 Biscetti L, Eusebi P, Salvadori N, Frattini G, Simoni S, Mollenhauer B, Engelborghs S, Tambasco N, Calabresi P, Parnetti L, Chiasserini D. Combination Of Cerebrospinal Fluid H-Fabp And Core Alzheimer'S Disease Biomarkers Improves The Differential Diagnosis Of Neurodegenerative Disorders Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.353  0.367
2016 Streffer J, Börjesson-Hanson A, Van Broeck B, Smekens P, Timmers M, Tesseur I, Tatikola K, Russu A, Sinha V, Salvadore G, Aguilar M, Frank A, Matias-Guiu J, Boada M, Baquero M, ... ... Engelborghs S, et al. O1-10-05: Pharmacodynamics of the Oral Bace Inhibitor JNJ-54861911 in Early Alzheimer's Disease Alzheimer's & Dementia. 12: P199-P200. DOI: 10.1016/J.Jalz.2016.06.350  0.35
2016 Goossens J, Van Mossevelde S, Van den Bossche T, Sieben A, Martin J, Goeman J, Paul de Deyn P, Van Broeckhoven C, van der Zee J, Engelborghs S. P4-120: Increased CSF Levels of Biomarkers for Neurodegeneration in FTLD-GRN Mutation Carriers Alzheimer's & Dementia. 12: P1058-P1059. DOI: 10.1016/J.Jalz.2016.06.2211  0.306
2016 Bosco P, Redolfi A, Bocchetta M, Ferrari C, Mega A, Galluzzi S, Assal F, Balasa M, Bastin C, Bougea A, Emek-Savas DD, Engelborghs S, Giannakopoulos P, Gold G, Grimmer T, et al. Impact of biomarkers on diagnostic confidence in clinical assessment of patients with suspected Alzheimer’s disease and high diagnostic uncertainty: An EADC study Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1871  0.328
2016 De Roeck EE, Paul de Deyn P, Engelborghs S, Dierckx E. P2-299: Brief Neuropsychological Screening Tests for the Detection of Alzheimer's Disease in an Early Phase: A Systematic Review Alzheimer's & Dementia. 12: P748-P748. DOI: 10.1016/J.Jalz.2016.06.1559  0.357
2016 Goossens J, Struyfs H, Niemantsverdriet E, Van den Bossche T, Van Mossevelde S, De Vil B, Sieben A, Martin J, Cras P, Goeman J, Paul de Deyn P, Van Broeckhoven C, van der Zee J, Engelborghs S. P2-153: Diagnostic Performance of Non-Phosphorylated TAU Fraction (PTAU REL) in CSF as Biomarker for Differential Dementia Diagnosis Alzheimer's & Dementia. 12: P672-P673. DOI: 10.1016/J.Jalz.2016.06.1320  0.407
2016 De Roeck EE, De Witte N, Dury S, Paul de Deyn P, Dierckx E, Engelborghs S. P1-407: Cognitive Frailty: A New Domain Added to The Comprehensive Frailty Assessment Alzheimer's & Dementia. 12: P590-P590. DOI: 10.1016/J.Jalz.2016.06.1159  0.411
2015 Van Mossevelde S, van der Zee J, Gijselinck I, Engelborghs S, Sieben A, Van Langenhove T, De Bleecker J, Baets J, Vandenbulcke M, Van Laere K, Ceyssens S, Van den Broeck M, Peeters K, Mattheijssens M, Cras P, et al. Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort. Brain : a Journal of Neurology. PMID 26674655 DOI: 10.1093/Brain/Awv358  0.337
2015 Gijselinck I, Van Mossevelde S, van der Zee J, Sieben A, Philtjens S, Heeman B, Engelborghs S, Vandenbulcke M, De Baets G, Bäumer V, Cuijt I, Van den Broeck M, Peeters K, Mattheijssens M, Rousseau F, et al. Loss of TBK1 is a frequent cause of frontotemporal dementia in a Belgian cohort. Neurology. PMID 26581300 DOI: 10.1212/Wnl.0000000000002220  0.343
2015 Struyfs H, Van Hecke W, Veraart J, Sijbers J, Slaets S, De Belder M, Wuyts L, Peters B, Sleegers K, Robberecht C, Van Broeckhoven C, De Belder F, Parizel PM, Engelborghs S. Diffusion Kurtosis Imaging: A Possible MRI Biomarker for AD Diagnosis? Journal of Alzheimer's Disease : Jad. 48: 937-48. PMID 26444762 DOI: 10.3233/Jad-150253  0.412
2015 Toledo JB, Zetterberg H, van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. Brain : a Journal of Neurology. 138: 2701-15. PMID 26220940 DOI: 10.1093/Brain/Awv199  0.41
2015 Bettens K, Vermeulen S, Van Cauwenberghe C, Heeman B, Asselbergh B, Robberecht C, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Cruts M, Van Broeckhoven C, Sleegers K. Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations. Molecular Neurodegeneration. 10: 30. PMID 26179372 DOI: 10.1186/S13024-015-0024-9  0.394
2015 Cuyvers E, De Roeck A, Van den Bossche T, Van Cauwenberghe C, Bettens K, Vermeulen S, Mattheijssens M, Peeters K, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K. Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study. The Lancet. Neurology. 14: 814-22. PMID 26141617 DOI: 10.1016/S1474-4422(15)00133-7  0.41
2015 Struyfs H, Niemantsverdriet E, Goossens J, Fransen E, Martin JJ, De Deyn PP, Engelborghs S. Cerebrospinal Fluid P-Tau181P: Biomarker for Improved Differential Dementia Diagnosis. Frontiers in Neurology. 6: 138. PMID 26136723 DOI: 10.3389/Fneur.2015.00138  0.47
2015 De Vos A, Jacobs D, Struyfs H, Fransen E, Andersson K, Portelius E, Andreasson U, De Surgeloose D, Hernalsteen D, Sleegers K, Robberecht C, Van Broeckhoven C, Zetterberg H, Blennow K, Engelborghs S, et al. C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26092348 DOI: 10.1016/J.Jalz.2015.05.012  0.403
2015 Sleegers K, Bettens K, De Roeck A, Van Cauwenberghe C, Cuyvers E, Verheijen J, Struyfs H, Van Dongen J, Vermeulen S, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Van Broeckhoven C. A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 1452-60. PMID 26086184 DOI: 10.1016/J.Jalz.2015.02.013  0.431
2015 Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ, Aalten P, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, ... ... Engelborghs S, et al. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. Jama. 313: 1924-38. PMID 25988462 DOI: 10.1001/Jama.2015.4668  0.821
2015 Le Bastard N, De Deyn PP, Engelborghs S. Importance and impact of preanalytical variables on Alzheimer disease biomarker concentrations in cerebrospinal fluid. Clinical Chemistry. 61: 734-43. PMID 25869575 DOI: 10.1373/Clinchem.2014.236679  0.385
2015 Cuyvers E, van der Zee J, Bettens K, Engelborghs S, Vandenbulcke M, Robberecht C, Dillen L, Merlin C, Geerts N, Graff C, Thonberg H, Chiang HH, Pastor P, Ortega-Cubero S, Pastor MA, et al. Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study. Neurobiology of Aging. 36: 2005.e15-22. PMID 25796131 DOI: 10.1016/J.Neurobiolaging.2015.02.014  0.47
2015 Vermeiren Y, Van Dam D, Aerts T, Engelborghs S, Martin JJ, De Deyn PP. The monoaminergic footprint of depression and psychosis in dementia with Lewy bodies compared to Alzheimer's disease. Alzheimer's Research & Therapy. 7: 7. PMID 25717350 DOI: 10.1186/S13195-014-0090-1  0.481
2015 Vos SJ, Verhey F, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Morbelli S, Frisoni GB, Drzezga A, Didic M, van Berckel BN, Simmons A, ... ... Engelborghs S, et al. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. Brain : a Journal of Neurology. 138: 1327-38. PMID 25693589 DOI: 10.1093/Brain/Awv029  0.824
2015 Niemantsverdriet E, Feyen BF, Le Bastard N, Martin JJ, Goeman J, De Deyn PP, Engelborghs S. Overdiagnosing Vascular Dementia using Structural Brain Imaging for Dementia Work-Up. Journal of Alzheimer's Disease : Jad. 45: 1039-43. PMID 25633672 DOI: 10.3233/Jad-142103  0.444
2015 Struyfs H, Van Broeck B, Timmers M, Fransen E, Sleegers K, Van Broeckhoven C, De Deyn PP, Streffer JR, Mercken M, Engelborghs S. Diagnostic Accuracy of Cerebrospinal Fluid Amyloid-β Isoforms for Early and Differential Dementia Diagnosis. Journal of Alzheimer's Disease : Jad. 45: 813-22. PMID 25633670 DOI: 10.3233/Jad-141986  0.461
2015 Bier JC, Verschraegen J, Vandenberghe R, Guillaume B, Picard G, Otte G, Mormont E, Gilles C, Segers K, Sieben A, Thiery E, Ventura M, De Deyn P, Deryck O, Versijpt J, ... ... Engelborghs S, et al. Clinical utility and applicability of biomarker-based diagnostic criteria for Alzheimer's disease: a BeDeCo survey. Acta Neurologica Belgica. PMID 25576445 DOI: 10.1007/S13760-014-0423-7  0.327
2015 Dorey A, Tholance Y, Vighetto A, Perret-Liaudet A, Lachman I, Krolak-Salmon P, Wagner U, Struyfs H, De Deyn PP, El-Moualij B, Zorzi W, Meyronet D, Streichenberger N, Engelborghs S, Kovacs GG, et al. Association of cerebrospinal fluid prion protein levels and the distinction between Alzheimer disease and Creutzfeldt-Jakob disease. Jama Neurology. 72: 267-75. PMID 25559883 DOI: 10.1001/Jamaneurol.2014.4068  0.478
2015 Rosseels J, Van den Brande J, Violet M, Jacobs D, Grognet P, Lopez J, Huvent I, Caldara M, Swinnen E, Papegaey A, Caillierez R, Buée-Scherrer V, Engelborghs S, Lippens G, Colin M, et al. Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnostics. The Journal of Biological Chemistry. 290: 4059-74. PMID 25540200 DOI: 10.1074/Jbc.M114.627919  0.381
2015 Slaets S, Van Acker F, Versijpt J, Hauth L, Goeman J, Martin JJ, De Deyn PP, Engelborghs S. Diagnostic value of MIBG cardiac scintigraphy for differential dementia diagnosis. International Journal of Geriatric Psychiatry. 30: 864-9. PMID 25363642 DOI: 10.1002/Gps.4229  0.401
2015 Van der Mussele S, Mariën P, Saerens J, Somers N, Goeman J, De Deyn PP, Engelborghs S. Psychosis associated behavioral and psychological signs and symptoms in mild cognitive impairment and Alzheimer's dementia. Aging & Mental Health. 19: 818-28. PMID 25323000 DOI: 10.1080/13607863.2014.967170  0.834
2015 Van der Mussele S, Le Bastard N, Saerens J, Somers N, Mariën P, Goeman J, De Deyn PP, Engelborghs S. Agitation-associated behavioral symptoms in mild cognitive impairment and Alzheimer's dementia. Aging & Mental Health. 19: 247-57. PMID 24962058 DOI: 10.1080/13607863.2014.924900  0.837
2015 Ribbens A, Smeets D, Terzopoulos V, Jain S, Sima DM, Struyfs H, Engelborghs S, Hecke WV. Admetrix: A new method for atrophy quantification in Alzheimer's disease Alzheimers & Dementia. 11: 876. DOI: 10.1016/J.Jalz.2015.08.078  0.398
2015 Struyfs H, Smeets D, Terzopoulos V, Slaets S, Wuyts L, Peters B, De Belder F, Parizel PM, Van Hecke W, Engelborghs S. P4-248: Resting state functional MRI as a possible biomarker for Alzheimer's disease: An innovative approach for robust extraction of the default mode network Alzheimer's & Dementia. 11: P876-P876. DOI: 10.1016/J.Jalz.2015.08.077  0.343
2015 Sleegers K, Verheijen J, Zee Jvd, Bettens K, Engelborghs S, Vandenbulcke M, Sanchez-Valle R, Benussi L, Mendonça Ad, Pastor P, Graff C, Borroni B, Vandenberghe R, Deyn PPD, Broeckhoven CV. Targeted re-sequencing of sorl1 in early-onset Alzheimer’s dementia: The european early onset dementia consortium Alzheimers & Dementia. 11: 253. DOI: 10.1016/J.Jalz.2015.07.484  0.404
2015 Niemantsverdriet E, Goossens J, Struyfs H, Martin J, Goeman J, De Deyn PP, Vanderstichele HM, Engelborghs S. O4-11-03: Limited impact of CSF biomarkers variability on clinical diagnosis in autopsy-confirmed Alzheimer's disease Alzheimer's & Dementia. 11: P296-P297. DOI: 10.1016/J.Jalz.2015.07.407  0.387
2015 Vanderstichele HM, Stephenson D, Shaw LM, Carrillo M, Umek R, Rajapakse H, Luthman J, Soares H, Gordon MF, Devanarayan V, Genius J, Berman R, Hendrix J, Romero K, Kaplow J, ... ... Engelborghs S, et al. O4-11-02: The path to regulatory qualification of cerebrospinal fluid biomarkers as enrichment tools in clinical trials of patients with early Alzheimer's disease: For the coalition against major diseases Alzheimer's & Dementia. 11: P296-P296. DOI: 10.1016/J.Jalz.2015.07.406  0.384
2015 Cacace R, Van den Bossche T, Engelborghs S, Vandenbulcke M, Vandenberghe R, De Deyn PP, Cras P, Sleegers K, Van Broeckhoven C. P3-017: Rare variants in PLD3 do not increase risk in a belgian cohort of early-onset Alzheimer dementia patients Alzheimer's & Dementia. 11: P626-P626. DOI: 10.1016/J.Jalz.2015.06.883  0.454
2015 Stoops E, Demeyer L, Engelborghs S, Struyfs H, Niemantsverdriet E, Sleegers K, Herbst V, Zerr I, Schmitz M, Van Broeckhoven C, Vanderstichele H. P2-072: Development of novel elisas for the quantification of both pan-ApoE and ApoE4 proteins in CSF and blood, and ApoE ε4 phenotyping Alzheimer's & Dementia. 11: P510-P510. DOI: 10.1016/J.Jalz.2015.06.609  0.321
2015 Novak GP, Gordon MF, Li DJ, Alexander M, Schaerer J, Roche F, Engelborghs S, Dubois B. Operationalizing the iwg2 and nia-aa diagnostic criteria for asymptomatic-at-risk for Alzheimer's disease or preclinical Alzheimer's disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.380  0.434
2015 Doorn LJCvWv, Koel-Simmelink MJ, Hausmann U, Klafki H, Struyfs H, Linning P, Knoelker H, Twaalfhoven H, Kuiperij HB, Vanmechelen E, Verbeek M, Engelborghs S, Wiltfang J, Teunissen CE. Standardization of a method for diagnostic biomarker validation for neurodegenerative diseases: App assays as example Alzheimers & Dementia. 11: 387. DOI: 10.1016/J.Jalz.2015.06.318  0.329
2014 Molinuevo JL, Blennow K, Dubois B, Engelborghs S, Lewczuk P, Perret-Liaudet A, Teunissen CE, Parnetti L. The clinical use of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 808-17. PMID 25150736 DOI: 10.1016/J.Jalz.2014.03.003  0.497
2014 Van der Mussele S, Fransen E, Struyfs H, Luyckx J, Mariën P, Saerens J, Somers N, Goeman J, De Deyn PP, Engelborghs S. Depression in mild cognitive impairment is associated with progression to Alzheimer's disease: a longitudinal study. Journal of Alzheimer's Disease : Jad. 42: 1239-50. PMID 25024328 DOI: 10.3233/Jad-140405  0.827
2014 Vermeiren Y, Van Dam D, Aerts T, Engelborghs S, De Deyn PP. Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease. Neurobiology of Aging. 35: 2691-700. PMID 24997673 DOI: 10.1016/J.Neurobiolaging.2014.05.031  0.428
2014 Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, ... ... Engelborghs S, et al. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Science Translational Medicine. 6: 243ra86. PMID 24990881 DOI: 10.1126/Scitranslmed.3009093  0.302
2014 Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, DeKosky ST, Gauthier S, Selkoe D, Bateman R, Cappa S, Crutch S, Engelborghs S, Frisoni GB, Fox NC, et al. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. The Lancet. Neurology. 13: 614-29. PMID 24849862 DOI: 10.1016/S1474-4422(14)70090-0  0.376
2014 Struyfs H, Molinuevo JL, Martin JJ, De Deyn PP, Engelborghs S. Validation of the AD-CSF-index in autopsy-confirmed Alzheimer's disease patients and healthy controls. Journal of Alzheimer's Disease : Jad. 41: 903-9. PMID 24705548 DOI: 10.3233/Jad-131085  0.47
2014 Vermeiren Y, Van Dam D, Aerts T, Engelborghs S, De Deyn PP. Brain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 41: 819-33. PMID 24685637 DOI: 10.3233/Jad-140309  0.445
2014 Engelborghs S, Gilles C, Ivanoiu A, Vandewoude M. Rationale and clinical data supporting nutritional intervention in Alzheimer's disease Acta Clinica Belgica. 69: 17-24. PMID 24635394 DOI: 10.1179/0001551213Z.0000000006  0.321
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Engelborghs S, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.313
2014 Slaets S, Vanmechelen E, Le Bastard N, Decraemer H, Vandijck M, Martin JJ, De Deyn PP, Engelborghs S. Increased CSF α-synuclein levels in Alzheimer's disease: correlation with tau levels. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S290-8. PMID 24439167 DOI: 10.1016/J.Jalz.2013.10.004  0.472
2014 Teunissen CE, Tumani H, Engelborghs S, Mollenhauer B. Biobanking of CSF: international standardization to optimize biomarker development. Clinical Biochemistry. 47: 288-92. PMID 24389077 DOI: 10.1016/J.Clinbiochem.2013.12.024  0.303
2014 Cuyvers E, Bettens K, Philtjens S, Van Langenhove T, Gijselinck I, van der Zee J, Engelborghs S, Vandenbulcke M, Van Dongen J, Geerts N, Maes G, Mattheijssens M, Peeters K, Cras P, Vandenberghe R, et al. Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia. Neurobiology of Aging. 35: 726.e11-9. PMID 24119542 DOI: 10.1016/J.Neurobiolaging.2013.09.009  0.392
2014 Van der Mussele S, Mariën P, Saerens J, Somers N, Goeman J, De Deyn PP, Engelborghs S. Behavioral syndromes in mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 38: 319-29. PMID 23963290 DOI: 10.3233/Jad-130596  0.814
2014 Engelborghs S, Slaets S, Acker FV, Versijpt J, Hauth L, Martin J, Deyn PPD. The Diagnostic Value Of Mibg Cardiac Scintigraphy For Differential Dementia Diagnosis Alzheimers & Dementia. 10: 544. DOI: 10.1016/J.Jalz.2014.05.874  0.325
2014 Engelborghs S, Niemantsverdriet E, Feyen B, Martin J, Goeman J, De Deyn PP. P2-197: VASCULAR DEMENTIA IS OVERDIAGNOSED WHEN STRUCTURAL BRAIN IMAGING IS USED IN THE CONTEXT OF STANDARD CLINICAL DIAGNOSTIC CRITERIA FOR DEMENTIA Alzheimer's & Dementia. 10: P543-P544. DOI: 10.1016/J.Jalz.2014.05.873  0.4
2014 Vermeiren Y, Van Dam D, Aerts T, Engelborghs S, De Deyn PP. P2-148: MONOAMINERGIC NEUROTRANSMITTER LEVELS IN POST-MORTEM BRAIN REGIONS OF PATIENTS WITH LEWY BODY AND ALZHEIMER'S DEMENTIA: ASSOCIATION WITH DEPRESSION AND PSYCHOSIS Alzheimer's & Dementia. 10: P526-P526. DOI: 10.1016/J.Jalz.2014.05.823  0.39
2014 Vanderstichele H, Demeyer L, Stoops E, Mauroo K, Struyfs H, Herbst V, Engelborghs S, Brix B. QUANTIFICATION OF CSF Aβ1-38, TOGETHER WITH APOLIPOPROTEINS E, CAN IMPROVE THE CLINICAL DIAGNOSTIC ACCURACY FOR AD OF THE CSF TAU AND Aβ ASSAYS Alzheimers & Dementia. 10: 512. DOI: 10.1016/J.Jalz.2014.05.787  0.519
2014 Dierckx E, Engelborghs S, Deyn PPD, Mussele SVd, Ponjaert-Kristoffersen I. The Montreal Cognitive Assessment Instrument: Influence Of Depressive Symptoms Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.583  0.334
2014 Van Broeck B, Struyfs H, Timmers M, Sleegers K, Van Broeckhoven C, De Deyn PP, Streffer JR, Mercken M, Engelborghs S. P1-136: DIAGNOSTIC ACCURACY OF CSF AMYLOID-B ISOFORMS FOR EARLY AND DIFFERENTIAL DEMENTIA DIAGNOSIS Alzheimer's & Dementia. 10: P349-P350. DOI: 10.1016/J.Jalz.2014.05.373  0.41
2014 Vermeiren Y, Van Dam D, Aerts T, Engelborghs S, De Deyn PP. P1-112: MONOAMINERGIC BRAIN TOPOCHEMISTRY IN ALZHEIMER'S DISEASE VERSUS HEALTHY ELDERLY Alzheimer's & Dementia. 10: P342-P342. DOI: 10.1016/J.Jalz.2014.05.349  0.411
2014 Van Cauwenberghe C, Bettens K, Engelborghs S, Vandenbulcke M, Vandenberghe RR, De Deyn PP, Cruts M, Van Broeckhoven C, Sleegers K. P1-053: OLFACTORY RECEPTOR COPY NUMBER VARIATION INVOLVED IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P322-P323. DOI: 10.1016/J.Jalz.2014.05.289  0.365
2014 Soetewey F, Struyfs H, Stoops E, Van Broeckhoven C, Vanderstichele H, Engelborghs S. P4-068: CLINICAL RELEVANCE OF APOE GENOTYPING AND APOLIPOPROTEIN E-ɛ4 IMMUNOASSAYS IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P808-P808. DOI: 10.1016/J.Jalz.2014.05.1583  0.417
2014 Vanderstichele H, Vanderstichele H, Devanarayan V, Shaw L, Jeromin A, Coart E, Engelborghs S. P4-058: IMPACT OF ANALYTICAL BIAS AND IMPRECISION OF CSF BIOMARKERS ON THEIR CLINICAL DIAGNOSTIC PERFORMANCE FOR AD DIAGNOSIS Alzheimer's & Dementia. 10: P803-P803. DOI: 10.1016/J.Jalz.2014.05.1573  0.397
2014 Van der Mussele S, Fransen E, Mariën P, Saerens J, Somers N, Goeman J, De Deyn PP, Engelborghs S. P3-154: BEHAVIORAL SYMPTOMS ASSOCIATED WITH PROGRESSION FROM MILD COGNITIVE IMPAIRMENT TO ALZHEIMER'S DISEASE: A LONGITUDINAL STUDY Alzheimer's & Dementia. 10: P684-P685. DOI: 10.1016/J.Jalz.2014.05.1244  0.508
2014 Marreiro A, Kolen KV, Plasman K, Depuydt G, Peeraer E, Daneels G, Fierens K, Temmerman L, Vandermeeren M, Hermans B, Deyn PPD, Engelborghs S, Gevaert K, Moechars D, Mercken M. Molecular Analysis of Tau in Rodent and Non-Rodent Models of Ad Alzheimers & Dementia. 10: 649. DOI: 10.1016/J.Jalz.2014.05.1147  0.39
2014 Bettens K, Cauwenberghe CV, Cuyvers E, Verheijen J, Roeck AD, Dongen JV, Vermeulen S, Engelborghs S, Vandenbulcke M, Vandenberghe RR, Deyn PPD, Broeckhoven CV, Sleegers K. HIGH SCORES ON A 22-GENE RISK SCORE FOR ALZHEIMER'S DEMENTIA CORRELATE WITH EARLIER ONSET AGE AND REDUCED CSF Aβ Alzheimers & Dementia. 10: 257. DOI: 10.1016/J.Jalz.2014.04.404  0.44
2014 Struyfs H, Van Hecke W, Slaets S, Van der Mussele S, De Belder M, Wuyts L, Peters B, De Belder F, Parizel P, Engelborghs S. O2-03-06: DIFFUSION KURTOSIS IMAGING: A BIOMARKER FOR EARLY DIAGNOSIS OF ALZHEIMER'S DISEASE? Alzheimer's & Dementia. 10: P169-P170. DOI: 10.1016/J.Jalz.2014.04.172  0.347
2014 Struyfs H, Molinuevo JL, Martin J, De Deyn PP, Engelborghs S. O1-09-05: VALIDATION OF THE AD-CSF INDEX IN AUTOPSY CONFIRMED AD PATIENTS AND HEALTHY CONTROLS Alzheimer's & Dementia. 10: P147-P148. DOI: 10.1016/J.Jalz.2014.04.108  0.398
2014 Cuyvers E, Bettens K, Engelborghs S, Vandenbulcke M, Merlin C, Dillen L, Mattheijssens M, Peeters K, Cras P, Vandenberghe RR, Deyn PD, Zee Jvd, Broeckhoven CV, Sleegers K. Analysis Of Sqstm1 In Patients With Early-Onset Alzheimer'S Disease Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.077  0.434
2013 Banzhaf-Strathmann J, Claus R, Mücke O, Rentzsch K, van der Zee J, Engelborghs S, De Deyn PP, Cruts M, van Broeckhoven C, Plass C, Edbauer D. Promoter DNA methylation regulates progranulin expression and is altered in FTLD. Acta Neuropathologica Communications. 1: 16. PMID 24252647 DOI: 10.1186/2051-5960-1-16  0.349
2013 Slaets S, Le Bastard N, Martin JJ, Sleegers K, Van Broeckhoven C, De Deyn PP, Engelborghs S. Cerebrospinal fluid Aβ1-40 improves differential dementia diagnosis in patients with intermediate P-tau181P levels. Journal of Alzheimer's Disease : Jad. 36: 759-67. PMID 23666174 DOI: 10.3233/Jad-130107  0.454
2013 Nalls MA, Duran R, Lopez G, Kurzawa-Akanbi M, McKeith IG, Chinnery PF, Morris CM, Theuns J, Crosiers D, Cras P, Engelborghs S, De Deyn PP, Van Broeckhoven C, Mann DM, Snowden J, et al. A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. Jama Neurology. 70: 727-35. PMID 23588557 DOI: 10.1001/Jamaneurol.2013.1925  0.343
2013 Van Bogaert P, Van Grinsven R, Tolson D, Wouters K, Engelborghs S, Van der Mussele S. Effects of SolCos model-based individual reminiscence on older adults with mild to moderate dementia due to Alzheimer disease: a pilot study. Journal of the American Medical Directors Association. 14: 528.e9-13. PMID 23583001 DOI: 10.1016/J.Jamda.2013.01.020  0.809
2013 Van Cauwenberghe C, Bettens K, Engelborghs S, Vandenbulcke M, Van Dongen J, Vermeulen S, Vandenberghe R, De Deyn PP, Van Broeckhoven C, Sleegers K. Complement receptor 1 coding variant p.Ser1610Thr in Alzheimer's disease and related endophenotypes. Neurobiology of Aging. 34: 2235.e1-6. PMID 23582656 DOI: 10.1016/J.Neurobiolaging.2013.03.008  0.389
2013 Molinuevo JL, Gispert JD, Dubois B, Heneka MT, Lleo A, Engelborghs S, Pujol J, de Souza LC, Alcolea D, Jessen F, Sarazin M, Lamari F, Balasa M, Antonell A, Rami L. The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study. Journal of Alzheimer's Disease : Jad. 36: 67-77. PMID 23524657 DOI: 10.3233/Jad-130203  0.455
2013 Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen KV, Geller F, Sottejeau Y, Harold D, Dourlen P, Grenier-Boley B, Kamatani Y, Delepine B, Demiautte F, Zelenika D, ... ... Engelborghs S, et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Molecular Psychiatry. 18: 1225-34. PMID 23399914 DOI: 10.1038/Mp.2013.1  0.309
2013 Slaets S, Le Bastard N, Theuns J, Sleegers K, Verstraeten A, De Leenheir E, Luyckx J, Martin JJ, Van Broeckhoven C, Engelborghs S. Amyloid pathology influences aβ1-42 cerebrospinal fluid levels in dementia with lewy bodies. Journal of Alzheimer's Disease : Jad. 35: 137-46. PMID 23364139 DOI: 10.3233/Jad-122176  0.491
2013 Vanderstichele HM, Shaw L, Vandijck M, Jeromin A, Zetterberg H, Blennow K, Teunissen C, Engelborghs S. Alzheimer disease biomarker testing in cerebrospinal fluid: a method to harmonize assay platforms in the absence of an absolute reference standard. Clinical Chemistry. 59: 710-2. PMID 23355631 DOI: 10.1373/Clinchem.2012.201830  0.34
2013 Cacace R, Van Cauwenberghe C, Bettens K, Gijselinck I, van der Zee J, Engelborghs S, Vandenbulcke M, Van Dongen J, Bäumer V, Dillen L, Mattheijssens M, Peeters K, Cruts M, Vandenberghe R, De Deyn PP, et al. C9orf72 G4C2 repeat expansions in Alzheimer's disease and mild cognitive impairment. Neurobiology of Aging. 34: 1712.e1-7. PMID 23352322 DOI: 10.1016/J.Neurobiolaging.2012.12.019  0.484
2013 Engelborghs S, Sleegers K, Van der Mussele S, Le Bastard N, Brouwers N, Van Broeckhoven C, De Deyn PP. Brain-specific tryptophan hydroxylase, TPH2, and 5-HTTLPR are associated with frontal lobe symptoms in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 35: 67-73. PMID 23334703 DOI: 10.3233/Jad-101305  0.823
2013 Van der Mussele S, Bekelaar K, Le Bastard N, Vermeiren Y, Saerens J, Somers N, Mariën P, Goeman J, De Deyn PP, Engelborghs S. Prevalence and associated behavioral symptoms of depression in mild cognitive impairment and dementia due to Alzheimer's disease. International Journal of Geriatric Psychiatry. 28: 947-58. PMID 23255479 DOI: 10.1002/Gps.3909  0.833
2013 Vermeiren Y, Le Bastard N, Van Hemelrijck A, Drinkenburg WH, Engelborghs S, De Deyn PP. Behavioral correlates of cerebrospinal fluid amino acid and biogenic amine neurotransmitter alterations in dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 488-98. PMID 23159046 DOI: 10.1016/J.Jalz.2012.06.010  0.414
2013 van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, Bäumer V, Maes G, Corsmit E, Borroni B, Padovani A, ... ... Engelborghs S, ... ... Engelborghs S, et al. A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Human Mutation. 34: 363-73. PMID 23111906 DOI: 10.1002/Humu.22244  0.324
2013 Le Bastard N, Aerts L, Sleegers K, Martin JJ, Van Broeckhoven C, De Deyn PP, Engelborghs S. Longitudinal stability of cerebrospinal fluid biomarker levels: fulfilled requirement for pharmacodynamic markers in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 807-22. PMID 23034521 DOI: 10.3233/JAD-2012-110029  0.375
2013 Le Bastard N, Coart E, Vanderstichele H, Vanmechelen E, Martin JJ, Engelborghs S. Comparison of two analytical platforms for the clinical qualification of Alzheimer's disease biomarkers in pathologically-confirmed dementia. Journal of Alzheimer's Disease : Jad. 33: 117-31. PMID 22936010 DOI: 10.3233/Jad-2012-121246  0.497
2013 Azermai M, Petrovic M, Engelborghs S, Elseviers MM, Van der Mussele S, Debruyne H, Van Bortel L, Vander Stichele RH. The effects of abrupt antipsychotic discontinuation in cognitively impaired older persons: a pilot study. Aging & Mental Health. 17: 125-32. PMID 22928861 DOI: 10.1080/13607863.2012.717255  0.366
2013 Van der Mussele S, Le Bastard N, Vermeiren Y, Saerens J, Somers N, Mariën P, Goeman J, De Deyn PP, Engelborghs S. Behavioral symptoms in mild cognitive impairment as compared with Alzheimer's disease and healthy older adults. International Journal of Geriatric Psychiatry. 28: 265-75. PMID 22549770 DOI: 10.1002/Gps.3820  0.829
2013 Engelborghs S. CSF Biomarkers for Alzheimer Disease Diagnosis: Recent and Future Perspectives Journal of Neurological Disorders. 1. DOI: 10.4172/2329-6895.1000E102  0.519
2013 Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Engelborghs S, et al. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nature Genetics. 45: 712-712. DOI: 10.1038/Ng0613-712A  0.356
2013 Engelborghs S, Stoops E, Brix B, Demeyer L, Jacobs D, Struyfs H, Vanmechelen E. P1-171: A new era of CSF biomarker testing in the field of Alzheimer's disease Alzheimer's & Dementia. 9: P211-P211. DOI: 10.1016/J.Jalz.2013.05.394  0.398
2013 Vos AD, Jacobs D, Vanmechelen E, Winderickx J, Brande JVd, Engelborghs S, Struyfs H, Blennow K, Zetterberg H. Detection and quantification of novel tau/phospho-tau epitopes in CSF using a multiplex assay approach Alzheimers & Dementia. 9: 332. DOI: 10.1016/J.Jalz.2013.04.185  0.309
2012 Engelborghs S, Le Bastard N. The role of CSF biomarkers in the diagnostic work-up of mixed vascular-degenerative dementia. Journal of the Neurological Sciences. 322: 197-9. PMID 22947896 DOI: 10.1016/J.Jns.2012.08.003  0.511
2012 del Campo M, Mollenhauer B, Bertolotto A, Engelborghs S, Hampel H, Simonsen AH, Kapaki E, Kruse N, Le Bastard N, Lehmann S, Molinuevo JL, Parnetti L, Perret-Liaudet A, Sáez-Valero J, Saka E, et al. Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update. Biomarkers in Medicine. 6: 419-30. PMID 22917144 DOI: 10.2217/Bmm.12.46  0.418
2012 Engelborghs S, Le Bastard N. The impact of cerebrospinal fluid biomarkers on the diagnosis of Alzheimer's disease. Molecular Diagnosis & Therapy. 16: 135-41. PMID 22646065 DOI: 10.1007/Bf03262201  0.511
2012 Naudé PJ, Nyakas C, Eiden LE, Ait-Ali D, van der Heide R, Engelborghs S, Luiten PG, De Deyn PP, den Boer JA, Eisel UL. Lipocalin 2: novel component of proinflammatory signaling in Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2811-23. PMID 22441986 DOI: 10.1096/Fj.11-202457  0.352
2012 Bettens K, Brouwers N, Engelborghs S, Lambert JC, Rogaeva E, Vandenberghe R, Le Bastard N, Pasquier F, Vermeulen S, Van Dongen J, Mattheijssens M, Peeters K, Mayeux R, St George-Hyslop P, Amouyel P, et al. Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk. Molecular Neurodegeneration. 7: 3. PMID 22248099 DOI: 10.1186/1750-1326-7-3  0.358
2012 Gijselinck I, Van Langenhove T, van der Zee J, Sleegers K, Philtjens S, Kleinberger G, Janssens J, Bettens K, Van Cauwenberghe C, Pereson S, Engelborghs S, Sieben A, De Jonghe P, Vandenberghe R, Santens P, et al. A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study. The Lancet. Neurology. 11: 54-65. PMID 22154785 DOI: 10.1016/S1474-4422(11)70261-7  0.316
2012 Meeus B, Verstraeten A, Crosiers D, Engelborghs S, Van den Broeck M, Mattheijssens M, Peeters K, Corsmit E, Elinck E, Pickut B, Vandenberghe R, Cras P, De Deyn PP, Van Broeckhoven C, Theuns J. DLB and PDD: a role for mutations in dementia and Parkinson disease genes? Neurobiology of Aging. 33: 629.e5-629.e18. PMID 22118943 DOI: 10.1016/J.Neurobiolaging.2011.10.014  0.392
2012 Vanderstichele H, Bibl M, Engelborghs S, Le Bastard N, Lewczuk P, Molinuevo JL, Parnetti L, Perret-Liaudet A, Shaw LM, Teunissen C, Wouters D, Blennow K. Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 8: 65-73. PMID 22047631 DOI: 10.1016/J.Jalz.2011.07.004  0.448
2012 Le Bastard N, Engelborghs S. The value of cerebrospinal fluid biomarkers for the differential diagnosis of dementia Neurodegenerative Disease Management. 2: 211-219. DOI: 10.2217/Nmt.12.11  0.48
2012 Sims R, Hollingworth P, Sweet R, Engelborghs S, Spalletta G, Mayeux R, Kamboh I, Williams J. Follow up of Alzheimer's disease with psychosis genome-wide association studies Alzheimers & Dementia. 8: 676. DOI: 10.1016/J.Jalz.2012.05.1831  0.372
2012 Bettens K, Cauwenberghe CV, Cuyvers E, Bastard NL, Engelborghs S, Vandenberghe R, Deyn PD, Broeckhoven CV, Sleegers K. Genetic association and interaction of Alzheimer's risk genes CLU, CR1, BIN1, PICALM and MS4A in a Flanders-Belgian cohort Alzheimers & Dementia. 8: 671. DOI: 10.1016/J.Jalz.2012.05.1815  0.321
2012 Dierckx E, Engelborghs S, Mussele SVd, Deyn PPD, Ponjaert-Kristoffersen I. Are depressive symptoms in mild cognitive impairment patients predictive for conversion to dementia Alzheimers & Dementia. 8: 481. DOI: 10.1016/J.Jalz.2012.05.1302  0.42
2011 van der Zee J, Van Langenhove T, Kleinberger G, Sleegers K, Engelborghs S, Vandenberghe R, Santens P, Van den Broeck M, Joris G, Brys J, Mattheijssens M, Peeters K, Cras P, De Deyn PP, Cruts M, et al. TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort. Brain : a Journal of Neurology. 134: 808-15. PMID 21354975 DOI: 10.1093/Brain/Awr007  0.339
2011 De Witte L, Brouns R, Kavadias D, Engelborghs S, De Deyn PP, Mariën P. Cognitive, affective and behavioural disturbances following vascular thalamic lesions: a review. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 47: 273-319. PMID 21111408 DOI: 10.1016/J.Cortex.2010.09.002  0.312
2011 Dierckx E, Engelborghs S, De Raedt R, De Deyn PP, D'Haenens E, Verte D, Ponjaert-Kristoffersen I. The 10-word learning task in the differential diagnosis of early Alzheimer's disease and elderly depression: A cross-sectional pilot study. Aging & Mental Health. 15: 113-21. PMID 20924811 DOI: 10.1080/13607863.2010.505228  0.4
2011 Engelborghs S, Le Bastard N, Feyen B, Goeman J, Martin J, De Deyn P. P2-096: Overdiagnosis of vascular dementia using structural brain imaging in the context of standard clinical diagnostic criteria Alzheimer's & Dementia. 7: S338-S339. DOI: 10.1016/J.Jalz.2011.05.986  0.346
2011 Slaets S, Le Bastard N, De Leenheir E, Luyckx J, Martin J, De Deyn P, Engelborghs S. P2-069: The CSF Aβ1-40/Aβ1-42 ratio for differential dementia diagnosis Alzheimer's & Dementia. 7: S329-S329. DOI: 10.1016/J.Jalz.2011.05.959  0.463
2011 Slaets S, Engelborghs S, Le Bastard N, De Deyn P, De Leenheir E, Luyckx J, Martin J. P1-113: Influence of AD pathology on CSF biomarkers in autopsy-confirmed Dementia with Lewy Bodies patients Alzheimer's & Dementia. 7: S146-S146. DOI: 10.1016/J.Jalz.2011.05.392  0.49
2011 Vermeiren Y, Le Bastard N, Van Hemelrijck A, Drinkenburg W, De Deyn P, Engelborghs S. P4-177: Correlates of cerebrospinal fluid neurotransmitter alterations with behavioral disturbances in dementia Alzheimer's & Dementia. 7: S765-S766. DOI: 10.1016/J.Jalz.2011.05.2200  0.42
2011 Engelborghs S. PL-04-02: Diagnostic value of CSF biomarkers for (differential) dementia diagnosis Alzheimer's & Dementia. 7: S673-S673. DOI: 10.1016/J.Jalz.2011.05.1940  0.376
2011 Van der Mussele S, Le Bastard N, Vermeiren Y, Saerens J, Somers N, Marien P, Jordens K, Van Buggenhout M, Goeman J, De Deyn P, Engelborghs S. P3-105: Prognostic value of frontal lobe symptoms in mild cognitive impairment for conversion to Alzheimer's disease Alzheimer's & Dementia. 7: S547-S548. DOI: 10.1016/J.Jalz.2011.05.1545  0.487
2011 Van der Mussele S, Le Bastard N, Vermeiren Y, Saerens J, Somers N, Marien P, Goeman J, De Deyn P, Engelborghs S. P3-104: Behavioral symptoms in mild cognitive impairment as compared to Alzheimer's disease and healthy elderly Alzheimer's & Dementia. 7: S547-S547. DOI: 10.1016/J.Jalz.2011.05.1544  0.519
2011 Dierckx E, Carlon M, Engelborghs S, Raedt RD, Deyn PD, Ponjaert-Kristoffersen I. Early detection of MCI: Is the MoCA more sensitive for cognitive decline than the MMSE (a pilot study) Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1511  0.344
2010 Aries MJ, Le Bastard N, Debruyne H, Van Buggenhout M, Nagels G, De Deyn PP, Engelborghs S. Relation between frontal lobe symptoms and dementia severity within and across diagnostic dementia categories. International Journal of Geriatric Psychiatry. 25: 1186-95. PMID 20957694 DOI: 10.1002/Gps.2481  0.455
2010 Lambert JC, Sleegers K, González-Pérez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, ... ... Engelborghs S, et al. The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. Journal of Alzheimer's Disease : Jad. 22: 247-55. PMID 20847397 DOI: 10.3233/Jad-2010-100933  0.409
2010 De Meyer G, Shapiro F, Vanderstichele H, Vanmechelen E, Engelborghs S, De Deyn PP, Coart E, Hansson O, Minthon L, Zetterberg H, Blennow K, Shaw L, Trojanowski JQ. Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people. Archives of Neurology. 67: 949-56. PMID 20697045 DOI: 10.1001/Archneurol.2010.179  0.393
2010 Brouwers N, Bettens K, Gijselinck I, Engelborghs S, Pickut BA, Van Miegroet H, Montoya AG, Mattheijssens M, Peeters K, De Deyn PP, Cruts M, Sleegers K, Van Broeckhoven C. Contribution of TARDBP to Alzheimer's disease genetic etiology. Journal of Alzheimer's Disease : Jad. 21: 423-30. PMID 20555136 DOI: 10.3233/Jad-2010-100198  0.421
2010 Chen CC, Engelborghs S, Dewaele S, Le Bastard N, Martin JJ, Vanhooren V, Libert C, De Deyn PP. Altered serum glycomics in Alzheimer disease: a potential blood biomarker? Rejuvenation Research. 13: 439-44. PMID 20426627 DOI: 10.1089/Rej.2009.0992  0.471
2010 Le Bastard N, Leurs J, Blomme W, De Deyn PP, Engelborghs S. Plasma amyloid-beta forms in Alzheimer's disease and non-Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 21: 291-301. PMID 20421698 DOI: 10.3233/Jad-2010-091501  0.462
2010 Bettens K, Brouwers N, Van Miegroet H, Gil A, Engelborghs S, De Deyn PP, Vandenberghe R, Van Broeckhoven C, Sleegers K. Follow-up study of susceptibility loci for Alzheimer's disease and onset age identified by genome-wide association. Journal of Alzheimer's Disease : Jad. 19: 1169-75. PMID 20308783 DOI: 10.3233/Jad-2010-1310  0.433
2010 Meeus B, Nuytemans K, Crosiers D, Engelborghs S, Peeters K, Mattheijssens M, Elinck E, Corsmit E, De Deyn PP, Van Broeckhoven C, Theuns J. Comprehensive genetic and mutation analysis of familial dementia with lewy bodies linked to 2q35-q36 Journal of Alzheimer's Disease. 20: 197-205. PMID 20164589 DOI: 10.3233/Jad-2010-1356  0.314
2010 Le Bastard N, Martin JJ, Vanmechelen E, Vanderstichele H, De Deyn PP, Engelborghs S. Added diagnostic value of CSF biomarkers in differential dementia diagnosis. Neurobiology of Aging. 31: 1867-76. PMID 19150153 DOI: 10.1016/J.Neurobiolaging.2008.10.017  0.489
2010 Le Bastard N, Bekelaar K, Elseviers M, Van Buggenhout M, Mariën P, Saerens J, Somers N, De Deyn PP, Engelborghs S. P4-009: Characterisation of Depression in Dementia and Mild Cognitive Impairment Alzheimer's & Dementia. 6: e23-e23. DOI: 10.1016/J.Jalz.2010.08.069  0.415
2010 Bettens K, Brouwers N, Gil A, Miegroet HV, Engelborghs S, Deyn PPD, Vandenberghe R, Sleegers K, Broeckhoven CV. In-depth molecular genetic analysis of CLU in Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.217  0.372
2010 Le Bastard N, Aerts L, De Deyn PP, Engelborghs S. P3-262: Longitudinal stability of CSF biomarker levels Alzheimer's & Dementia. 6: S528-S528. DOI: 10.1016/J.Jalz.2010.05.1762  0.303
2010 Le Bastard N, De Deyn PP, Engelborghs S. P3-231: Plasma beta-amyloid levels: Diagnostic markers for dementia diagnosis? Alzheimer's & Dementia. 6: S519-S519. DOI: 10.1016/J.Jalz.2010.05.1730  0.362
2010 Dierckx E, Engelborghs S, Raedt RD, Buggenhout MV, Deyn PPD, Ponjaert-Kristoffersen I. Predicting conversion to Alzheimer's disease in Mild Cognitive Impairment: cued recall versus free delayed recall Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1197  0.399
2009 De Smet HJ, Baillieux H, Wackenier P, De Praeter M, Engelborghs S, Paquier PF, De Deyn PP, Mariën P. Long-term cognitive deficits following posterior fossa tumor resection: a neuropsychological and functional neuroimaging follow-up study. Neuropsychology. 23: 694-704. PMID 19899828 DOI: 10.1037/A0016106  0.339
2009 Koopman K, Le Bastard N, Martin JJ, Nagels G, De Deyn PP, Engelborghs S. Improved discrimination of autopsy-confirmed Alzheimer's disease (AD) from non-AD dementias using CSF P-tau(181P). Neurochemistry International. 55: 214-8. PMID 19524111 DOI: 10.1016/J.Neuint.2009.02.017  0.5
2009 Bettens K, Brouwers N, Engelborghs S, Van Miegroet H, De Deyn PP, Theuns J, Sleegers K, Van Broeckhoven C. APP and BACE1 miRNA genetic variability has no major role in risk for Alzheimer disease. Human Mutation. 30: 1207-13. PMID 19462468 DOI: 10.1002/Humu.21027  0.343
2009 Sleegers K, Brouwers N, Bettens K, Engelborghs S, van Miegroet H, De Deyn PP, Van Broeckhoven C. No association between CALHM1 and risk for Alzheimer dementia in a Belgian population. Human Mutation. 30: E570-4. PMID 19191332 DOI: 10.1002/Humu.20990  0.412
2009 Debruyne H, Van Buggenhout M, Le Bastard N, Aries M, Audenaert K, De Deyn PP, Engelborghs S. Is the geriatric depression scale a reliable screening tool for depressive symptoms in elderly patients with cognitive impairment? International Journal of Geriatric Psychiatry. 24: 556-62. PMID 19132643 DOI: 10.1002/Gps.2154  0.346
2009 Sleegers K, Bettens K, Brouwers N, Engelborghs S, van Miegroet H, De Deyn PP, Van Broeckhoven C. Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia. Human Mutation. 30: E338-44. PMID 18853460 DOI: 10.1002/Humu.20909  0.415
2009 Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Engelborghs S, et al. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nature Genetics. 41: 1156-1156. DOI: 10.1038/Ng1009-1156D  0.356
2009 Bettens K, Brouwers N, Van Miegroet H, Engelborghs S, De Deyn P, Theuns J, Sleegers K, Van Broeckhoven C. O4-01-02: APP and BACE1 miRNA genetic variability in risk for Alzheimer's disease Alzheimer's & Dementia. 5: P149-P149. DOI: 10.1016/J.Jalz.2009.05.514  0.308
2008 Dierckx E, Engelborghs S, De Raedt R, Van Buggenhout M, De Deyn PP, Verleye G, Verte D, Ponjaert-Kristoffersen I. Differentiation between dementia and depression among older persons: can the difference between actual and premorbid intelligence be useful? Journal of Geriatric Psychiatry and Neurology. 21: 242-9. PMID 19017781 DOI: 10.1177/0891988708324938  0.387
2008 De Witte L, Engelborghs S, Verhoeven J, De Deyn PP, Mariën P. Disrupted auto-activation, dysexecutive and confabulating syndrome following bilateral thalamic and right putaminal stroke. Behavioural Neurology. 19: 145-51. PMID 18641434 DOI: 10.1155/2008/693671  0.301
2008 Brouwers N, Sleegers K, Engelborghs S, Maurer-Stroh S, Gijselinck I, van der Zee J, Pickut BA, Van den Broeck M, Mattheijssens M, Peeters K, Schymkowitz J, Rousseau F, Martin JJ, Cruts M, De Deyn PP, et al. Genetic variability in progranulin contributes to risk for clinically diagnosed Alzheimer disease. Neurology. 71: 656-64. PMID 18565828 DOI: 10.1212/01.Wnl.0000319688.89790.7A  0.317
2008 Bettens K, Brouwers N, Engelborghs S, De Deyn PP, Van Broeckhoven C, Sleegers K. SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population. Human Mutation. 29: 769-70. PMID 18407551 DOI: 10.1002/Humu.20725  0.372
2008 Mariën P, Baillieux H, De Smet HJ, Engelborghs S, Wilssens I, Paquier P, De Deyn PP. Cognitive, linguistic and affective disturbances following a right superior cerebellar artery infarction: a case study. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 45: 527-36. PMID 18396269 DOI: 10.1016/J.Cortex.2007.12.010  0.326
2008 Bettens K, Brouwers N, Engelborghs S, De Pooter T, De Deyn PP, Sleegers K, Van Broeckhoven C. DNMBP is genetically associated with Alzheimer dementia in the Belgian population. Neurobiology of Aging. 30: 2000-9. PMID 18359537 DOI: 10.1016/J.Neurobiolaging.2008.02.003  0.356
2008 Engelborghs S, Vloeberghs E, Le Bastard N, Van Buggenhout M, Mariën P, Somers N, Nagels G, Pickut BA, De Deyn PP. The dopaminergic neurotransmitter system is associated with aggression and agitation in frontotemporal dementia. Neurochemistry International. 52: 1052-60. PMID 18093695 DOI: 10.1016/J.Neuint.2007.10.018  0.788
2008 Engelborghs S, De Vreese K, Van de Casteele T, Vanderstichele H, Van Everbroeck B, Cras P, Martin JJ, Vanmechelen E, De Deyn PP. Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia. Neurobiology of Aging. 29: 1143-59. PMID 17428581 DOI: 10.1016/j.neurobiolaging.2007.02.016  0.366
2008 Le Bastard N, De Deyn PP, Engelborghs S. P1-349: Plasma amyloid isoforms allow screening for mild cognitive impairment among healthy elderly Alzheimer's & Dementia. 4: T321-T321. DOI: 10.1016/J.Jalz.2008.05.930  0.381
2008 Engelborghs S, Le Bastard N, De Deyn PP. P1-344: Plasma amyloid isoforms in non-Alzheimer's disease patients Alzheimer's & Dementia. 4: T320-T320. DOI: 10.1016/J.Jalz.2008.05.925  0.42
2008 Le Bastard N, Van Buggenhout M, De Deyn PP, Engelborghs S. P1-166: CSF biomarkers predict conversion to dementia in mild cognitive impairment Alzheimer's & Dementia. 4: T256-T257. DOI: 10.1016/J.Jalz.2008.05.754  0.445
2008 Engelborghs S, Aries M, Le Bastard N, Debruyne H, Van Buggenhout M, Nagels G, De Deyn PP. O3-06-05: Progression of frontal lobe symptoms in frontotemporal dementia and dementia with Lewy bodies as compared with Alzheimer's disease Alzheimer's & Dementia. 4: T171-T172. DOI: 10.1016/J.Jalz.2008.05.454  0.494
2008 Le Bastard N, Van Buggenhout M, Debruyne H, Aries M, De Deyn PP, Engelborghs S. O2-07-02: Is the geriatric depression scale a reliable screening tool for depressive symptoms in elderly patients with cognitive impairment? Alzheimer's & Dementia. 4: T146-T146. DOI: 10.1016/J.Jalz.2008.05.359  0.456
2008 Engelborghs S, Le Bastard N, Vloeberghs E, Van Buggenhout M, Nagels G, Pickut BA, De Deyn PP. P3-392: The dopaminergic neurotransmitter system is associated with aggression and agitation in frontotemporal dementia Alzheimer's & Dementia. 4: T636-T636. DOI: 10.1016/J.Jalz.2008.05.1962  0.773
2008 Sleegers K, Bettens K, Engelborghs S, Brouwers N, van Miegroet H, De Deyn PP, Van Broeckhoven C. P3-266: GAB2 and risk for Alzheimer's dementia in a Belgian population Alzheimer's & Dementia. 4: T600-T600. DOI: 10.1016/J.Jalz.2008.05.1834  0.434
2008 Brouwers N, Sleegers K, Engelborghs S, Maurer-Stroh S, Gijselinck I, van der Zee J, Pickut B, Van den Broeck M, Mattheijssens M, Peeters K, Schymkowitz J, Rousseau F, Martin J, Cruts M, De Deyn PP, et al. P3-206: Genetic variability at the progranulin locus contributes to risk for Alzheimer's disease Alzheimer's & Dementia. 4: T581-T581. DOI: 10.1016/J.Jalz.2008.05.1773  0.308
2008 Bettens K, Brouwers N, Engelborghs S, De Deyn P, Van Broeckhoven C, Sleegers K. P3-202: The neuronal sorting receptor SORL1 is genetically associated with increased risk for late-onset Alzheimer's disease in the Belgian population Alzheimer's & Dementia. 4: T579-T580. DOI: 10.1016/J.Jalz.2008.05.1769  0.349
2008 Le Bastard N, Martin J, De Deyn PP, Engelborghs S. P3-080: Value of CSF biomarkers in differential dementia diagnosis Alzheimer's & Dementia. 4: T541-T541. DOI: 10.1016/J.Jalz.2008.05.1644  0.404
2008 Engelborghs S, Koopman K, Le Bastard N, Martin J, De Deyn PP. P3-068: Improved discrimination of Alzheimer's disease from other dementias using cerebrospinal fluid P-tau181P Alzheimer's & Dementia. 4: T537-T537. DOI: 10.1016/J.Jalz.2008.05.1632  0.458
2007 Mariën P, Brouns R, Engelborghs S, Wackenier P, Verhoeven J, Ceulemans B, De Deyn PP. Cerebellar cognitive affective syndrome without global mental retardation in two relatives with Gillespie syndrome. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 44: 54-67. PMID 18387531 DOI: 10.1016/J.Cortex.2005.12.001  0.363
2007 Brouwers N, Nuytemans K, van der Zee J, Gijselinck I, Engelborghs S, Theuns J, Kumar-Singh S, Pickut BA, Pals P, Dermaut B, Bogaerts V, De Pooter T, Serneels S, Van den Broeck M, Cuijt I, et al. Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family. Archives of Neurology. 64: 1436-46. PMID 17923627 DOI: 10.1001/Archneur.64.10.1436  0.372
2007 Le Bastard N, Van Buggenhout M, De Leenheir E, Martin JJ, De Deyn PP, Engelborghs S. LOW specificity limits the use of the cerebrospinal fluid AB1-42/P-TAU181P ratio to discriminate alzheimer's disease from vascular dementia. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 923-4; author reply . PMID 17702886 DOI: 10.1093/Gerona/62.8.923  0.461
2007 Engelborghs S, Sleegers K, Cras P, Brouwers N, Serneels S, De Leenheir E, Martin JJ, Vanmechelen E, Van Broeckhoven C, De Deyn PP. No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease. Brain : a Journal of Neurology. 130: 2320-6. PMID 17586559 DOI: 10.1093/Brain/Awm136  0.409
2007 Wollmer MA, Sleegers K, Ingelsson M, Zekanowski C, Brouwers N, Maruszak A, Brunner F, Huynh KD, Kilander L, Brundin RM, Hedlund M, Giedraitis V, Glaser A, Engelborghs S, De Deyn PP, et al. Association study of cholesterol-related genes in Alzheimer's disease. Neurogenetics. 8: 179-88. PMID 17387528 DOI: 10.1007/S10048-007-0087-Z  0.424
2007 Nagels G, Engelborghs S, Vloeberghs E, Lemmens W, Pickut BA, De Deyn PP. Correlation between actigraphy and nurses' observation of activity in dementia. International Journal of Geriatric Psychiatry. 22: 84-6. PMID 17171751 DOI: 10.1002/Gps.1647  0.722
2006 Brouwers N, Sleegers K, Engelborghs S, Bogaerts V, Serneels S, Kamali K, Corsmit E, De Leenheir E, Martin JJ, De Deyn PP, Van Broeckhoven C, Theuns J. Genetic risk and transcriptional variability of amyloid precursor protein in Alzheimer's disease. Brain : a Journal of Neurology. 129: 2984-91. PMID 16931535 DOI: 10.1093/Brain/Awl212  0.368
2006 Engelborghs S, Maertens K, Mariën P, Vloeberghs E, Somers N, Nagels G, De Deyn PP. Behavioural and neuropsychological correlates of frontal lobe features in dementia. Psychological Medicine. 36: 1173-82. PMID 16700962 DOI: 10.1017/S003329170600777X  0.767
2006 Nagels G, Engelborghs S, Vloeberghs E, Van Dam D, Pickut BA, De Deyn PP. Actigraphic measurement of agitated behaviour in dementia. International Journal of Geriatric Psychiatry. 21: 388-93. PMID 16534768 DOI: 10.1002/Gps.1483  0.752
2006 van der Zee J, Rademakers R, Engelborghs S, Gijselinck I, Bogaerts V, Vandenberghe R, Santens P, Caekebeke J, De Pooter T, Peeters K, Lübke U, Van den Broeck M, Martin JJ, Cruts M, De Deyn PP, et al. A Belgian ancestral haplotype harbours a highly prevalent mutation for 17q21-linked tau-negative FTLD. Brain : a Journal of Neurology. 129: 841-52. PMID 16495329 DOI: 10.1093/Brain/Awl029  0.303
2006 Engelborghs S, Maertens K, Vloeberghs E, Aerts T, Somers N, Mariën P, De Deyn PP. Neuropsychological and behavioural correlates of CSF biomarkers in dementia. Neurochemistry International. 48: 286-95. PMID 16434124 DOI: 10.1016/J.Neuint.2005.11.002  0.782
2006 Engelborghs S, Dermaut B, Mariën P, Symons A, Vloeberghs E, Maertens K, Somers N, Goeman J, Rademakers R, Van den Broeck M, Pickut B, Cruts M, Van Broeckhoven C, De Deyn PP. Dose dependent effect of APOE epsilon4 on behavioral symptoms in frontal lobe dementia. Neurobiology of Aging. 27: 285-92. PMID 16399213 DOI: 10.1016/J.Neurobiolaging.2005.02.005  0.808
2006 Brouwers N, Sleegers K, Engelborghs S, Bogaerts V, van Duijn CM, De Deyn PP, Van Broeckhoven C, Dermaut B. The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years. Neuroscience Letters. 392: 72-4. PMID 16214290 DOI: 10.1016/J.Neulet.2005.08.064  0.436
2006 Vos SJ, Bos I, Verhey FR, Engelborghs S, Lleó A, Johannsen P, Freund-Levi Y, Frölich L, Vandenberghe R, Frisoni GB, Blin O, Richardson J, Bordet R, Scheltens P, Ramakers IH, et al. P2-270: INCREASED CSF AMYLOID-β 1-38 AND 1-40 CONCENTRATIONS IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT WITH TAU BUT WITHOUT AMYLOID PATHOPHYSIOLOGY Alzheimer's & Dementia. 14: P780-P781. DOI: 10.1016/J.Jalz.2018.06.959  0.422
2006 ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Wallin A, Molinuevo JL, Tsolaki M, Verhey FR, et al. F1-02-03: MRI PREDICTORS OF AMYLOID PATHOLOGY: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY Alzheimer's & Dementia. 14: P202-P204. DOI: 10.1016/J.Jalz.2018.06.2309  0.388
2006 Westwood S, Baird AL, Anand SN, Shi L, Nevado-Holgado AJ, Kormilitzin A, Hye A, Ashton NJ, Morgan A, Touchard S, Morgan P, Bos I, Vos SJ, Vandenberghe R, Scheltens P, ... Engelborghs S, et al. F1-02-02: DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN AND ALZHEIMER'S DISEASE PROGRESSION Alzheimer's & Dementia. 14: P201-P202. DOI: 10.1016/J.Jalz.2018.06.2308  0.381
2006 Ingala S, ten Kate M, Redolfi A, Wottschel V, Peira E, Bos I, Vos SJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Wallin A, Molinuevo JL, et al. P2-458: PREDICTING COGNITIVE DECLINE THROUGH STRUCTURAL MRI BIOMARKERS: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY Alzheimer's & Dementia. 14: P895-P896. DOI: 10.1016/J.Jalz.2018.06.1151  0.427
2006 Engelborghs S, Mariën P, Vloeberghs E, Somers N, Nagels G, De Deyn PP. P1-425: Behavioral and neuropsychological correlates of frontal lobe features in dementia Alzheimer's & Dementia. 2: S222-S222. DOI: 10.1016/J.Jalz.2006.05.804  0.767
2006 Engelborghs S, De Vreese K, Van de Casteele T, Vanderstichele H, Van Everbroeck B, Cras P, Martin J, Vanmechelen E, De Deyn PP. O3-01-06: Diagnostic performance of a CSF-biomarker panel compared to clinical diagnosis in 100 autopsy-confirmed dementia cases Alzheimer's & Dementia. 2: S52-S53. DOI: 10.1016/J.Jalz.2006.05.192  0.362
2006 Engelborghs S, Nagels G, Vloeberghs E, Pickut BA, De Deyn PP. P4-176: Actigraphic measurement of agitated behavior in Dementia Alzheimer's & Dementia. 2: S568-S568. DOI: 10.1016/J.Jalz.2006.05.1915  0.763
2006 Rademakers R, Sleegers K, Pals P, Nuytemans K, Lohmann E, Durr A, Engelborghs S, Pooter Td, Broeck MVd, Pickut B, Cruts M, Deyn PD, Farrer M, Brice A, Broeckhoven CV. P3-159: MAPT H1 subhaplotyping in european PD association samples implicates tau splicing in early-onset parkinson’s disease susceptibility Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1427  0.31
2006 Bogaerts V, De Graeve S, Engelborghs S, van der Zee J, Peeters K, Stolz F, Van Dijck P, Theuns J, De Deyn PP, Thevelein J, Van Broeckhoven C. P3-158: A novel locus for autosomal dominant dementia with Lewy bodies on chromosome 2Q35-36 Alzheimer's & Dementia. 2: S420-S420. DOI: 10.1016/J.Jalz.2006.05.1426  0.301
2005 Engelborghs S, Maertens K, Nagels G, Vloeberghs E, Mariën P, Symons A, Ketels V, Estercam S, Somers N, De Deyn PP. Neuropsychiatric symptoms of dementia: cross-sectional analysis from a prospective, longitudinal Belgian study. International Journal of Geriatric Psychiatry. 20: 1028-37. PMID 16250064 DOI: 10.1002/Gps.1395  0.765
2005 De Witte L, Wilssens I, Engelborghs S, De Deyn PP, Mariën P. Impairment of syntax and lexical semantics in a patient with bilateral paramedian thalamic infarction. Brain and Language. 96: 69-77. PMID 16226805 DOI: 10.1016/J.Bandl.2005.08.011  0.31
2005 Van Dam D, Marescau B, Engelborghs S, Cremers T, Mulder J, Staufenbiel M, De Deyn PP. Analysis of cholinergic markers, biogenic amines, and amino acids in the CNS of two APP overexpression mouse models. Neurochemistry International. 46: 409-22. PMID 15737439 DOI: 10.1016/J.Neuint.2004.11.005  0.349
2005 De Deyn PP, Engelborghs S, Saerens J, Goeman J, Mariën P, Maertens K, Nagels G, Martin JJ, Pickut BA. The Middelheim Frontality Score: a behavioural assessment scale that discriminates frontotemporal dementia from Alzheimer's disease. International Journal of Geriatric Psychiatry. 20: 70-9. PMID 15578673 DOI: 10.1002/Gps.1249  0.503
2004 Vloeberghs E, Van Dam D, Engelborghs S, Nagels G, Staufenbiel M, De Deyn PP. Altered circadian locomotor activity in APP23 mice: a model for BPSD disturbances. The European Journal of Neuroscience. 20: 2757-66. PMID 15548219 DOI: 10.1111/J.1460-9568.2004.03755.X  0.747
2004 Engelborghs S, Holmes C, McCulley M, De Deyn PP. 5-HT2A receptor polymorphism may modulate antipsychotic treatment response in Alzheimer's disease International Journal of Geriatric Psychiatry. 19: 1108-1109. PMID 15497194 DOI: 10.1002/Gps.1179  0.332
2004 Engelborghs S, Vloeberghs E, Maertens K, Mariën P, Somers N, Symons A, Clement F, Ketels V, Saerens J, Goeman J, Pickut BA, Vandevivere J, De Deyn PP. Correlations between cognitive, behavioural and psychological findings and levels of vitamin B12 and folate in patients with dementia. International Journal of Geriatric Psychiatry. 19: 365-70. PMID 15065230 DOI: 10.1002/Gps.1092  0.786
2004 Engelborghs S, Holmes C, McCulley M, De Deyn PP. P4-086 5-HT2A receptor polymorphism may modulate antipsychotic treatment response in Alzheimer's disease Neurobiology of Aging. 25: S498-S499. DOI: 10.1016/S0197-4580(04)81644-0  0.351
2004 Engelborghs S, Dermaut B, Mariën P, Symons A, Vloeberghs E, Maertens K, Somers N, Goeman J, Rademakers R, Van Den Broeck M, Pickut BA, Cruts M, Van Broeckhoven C, De Deyn PP. P4-033 Dose dependent effect of APOE ε4 on behavioral symptoms in frontal lobe dementia patients Neurobiology of Aging. 25: S482. DOI: 10.1016/S0197-4580(04)81591-4  0.772
2004 De Deyn PP, Engelborghs S, Saerens J, Goeman J, Mariën P, Maertens K, Nagels G, Pickut BA. P3-352 The middelheim frontality score: a behavioral assessment scale that discriminates frontotemporal dementia from Alzheimer's disease Neurobiology of Aging. 25: S455. DOI: 10.1016/S0197-4580(04)81501-X  0.474
2004 Engelborghs S, Maertens K, Vloeberghs E, Mariën P, Symons A, Ketels V, Somers N, Nagels G, Marescau B, De Deyn PP. P3-037 CSF dopac levels predict aggressive and agitated behavior in FTD patients Neurobiology of Aging. 25: S362. DOI: 10.1016/S0197-4580(04)81191-6  0.735
2004 Engelborghs S, Maertens K, Vloeberghs E, Mariën P, Symons A, Ketels V, Somers N, Nagels G, De Deyn PP. P1-052 A prospective, longitudinal Belgian study on behavioral and psychological signs and symptoms of dementia Neurobiology of Aging. 25: S109. DOI: 10.1016/S0197-4580(04)80366-X  0.774
2004 Dermaut B, Kumar-Singh S, Engelborghs S, Theuns J, Rademakers R, Peeters K, Claes S, Cruts M, Martin J, De Deyn P, Van Broeckhoven C. O3-05-01 A novel presenilin 1 mutation (gly183val) is associated with pick's disease in the absence of β-amyloid plaques Neurobiology of Aging. 25: S61. DOI: 10.1016/S0197-4580(04)80206-9  0.318
2003 Engelborghs S, Dermaut B, Goeman J, Saerens J, Mariën P, Pickut BA, Van den Broeck M, Serneels S, Cruts M, Van Broeckhoven C, De Deyn PP. Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 1148-51. PMID 12876259 DOI: 10.1136/Jmg.40.11.814  0.503
2001 Engelborghs S, De Deyn PP. Biological and genetic markers of sporadic Alzheimer's disease. Acta Medica Okayama. 55: 55-63. PMID 11332200 DOI: 10.18926/AMO/32010  0.345
1999 Engelborghs S, De Brabander M, De Crée J, D'Hooge R, Geerts H, Verhaegen H, De Deyn PP. Unchanged levels of interleukins, neopterin, interferon-gamma and tumor necrosis factor-alpha in cerebrospinal fluid of patients with dementia of the Alzheimer type. Neurochemistry International. 34: 523-30. PMID 10402228 DOI: 10.1016/S0197-0186(99)00031-5  0.306
1999 De Deyn PP, Goeman J, Engelborghs S, Hauben U, D'Hooge R, Baro F, Pickut BA. From neuronal and vascular impairment to dementia. Pharmacopsychiatry. 32: 17-24. PMID 10338104 DOI: 10.1055/S-2007-979232  0.38
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