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Howard Worman, M.D. - Publications

Affiliations: 
Columbia University College of Physicians and Surgeons, New York, NY, United States 
Area:
Lamins, Inner nuclear membrane proteins
Website:
http://asp.cpmc.columbia.edu/facdb/profile_list.asp?uni=hjw14&DepAffil=Medicine

206 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Antoku S, Wu W, Joseph LC, Morrow JP, Worman HJ, Gundersen GG. ERK1/2 Phosphorylation of FHOD Connects Signaling and Nuclear Positioning Alternations in Cardiac Laminopathy. Developmental Cell. 51: 602-616.e12. PMID 31794718 DOI: 10.1016/j.devcel.2019.10.023  0.72
2019 Muchir A, Worman HJ. Emery-Dreifuss muscular dystrophy: focal point nuclear envelope. Current Opinion in Neurology. 32: 728-734. PMID 31460960 DOI: 10.1097/WCO.0000000000000741  1
2019 Shin JY, Hernandez-Ono A, Fedotova T, Östlund C, Lee MJ, Gibeley SB, Liang CC, Dauer WT, Ginsberg HN, Worman HJ. Nuclear envelope-localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis. The Journal of Clinical Investigation. 130. PMID 31408437 DOI: 10.1172/JCI129769  0.32
2019 Östlund C, Chang W, Gundersen GG, Worman HJ. Pathogenic mutations in genes encoding nuclear envelope proteins and defective nucleocytoplasmic connections. Experimental Biology and Medicine (Maywood, N.J.). 1535370219862243. PMID 31299860 DOI: 10.1177/1535370219862243  0.32
2019 Wang Y, Shin JY, Nakanishi K, Homma S, Kim GJ, Tanji K, Joseph LC, Morrow JP, Stewart CL, Dauer WT, Worman HJ. Postnatal Development of Mice with Combined Genetic Depletions of Lamin A/C, Emerin and Lamina-associated Polypeptide 1. Human Molecular Genetics. PMID 31009944 DOI: 10.1093/hmg/ddz082  0.48
2019 Chang W, Wang Y, Luxton GWG, Östlund C, Worman HJ, Gundersen GG. Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. Proceedings of the National Academy of Sciences of the United States of America. 116: 3578-3583. PMID 30808750 DOI: 10.1073/pnas.1809683116  0.32
2018 Nagy PL, Worman HJ. Next-Generation Sequencing and Mutational Analysis: Implications for Genes Encoding LINC Complex Proteins. Methods in Molecular Biology (Clifton, N.J.). 1840: 321-336. PMID 30141054 DOI: 10.1007/978-1-4939-8691-0_22  0.36
2018 Chatzifrangkeskou M, Yadin D, Marais T, Chardonnet S, Cohen-Tannoudji M, Mougenot N, Schmitt A, Crasto S, Di Pasquale E, Macquart C, Tanguy Y, Jebeniani I, Pucéat M, Morales Rodriguez B, Goldmann WH, ... ... Worman HJ, et al. Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation. Human Molecular Genetics. PMID 29878125 DOI: 10.1093/hmg/ddy215  1
2018 Choi JC, Wu W, Phillips E, Plevin R, Sera F, Homma S, Worman HJ. Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival. Human Molecular Genetics. PMID 29668927 DOI: 10.1093/hmg/ddy134  0.72
2017 Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow JP, Worman HJ, Muchir A. Decreased WNT/β-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene. Human Molecular Genetics. PMID 28069793 DOI: 10.1093/hmg/ddw389  1
2016 Wu W, Chordia MD, Hart BP, Kumarasinghe ES, Ji MK, Bhargava A, Lawlor MW, Shin JY, Sera F, Homma S, Muchir A, Khire UR, Worman HJ. Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation. Bioorganic & Medicinal Chemistry. PMID 28011205 DOI: 10.1016/j.bmc.2016.12.014  1
2016 Le Dour C, Wu W, Béréziat V, Capeau J, Vigouroux C, Worman HJ. Extracellular Matrix Remodeling and Transforming Growth Factor-β Signaling Abnormalities Induced by Lamin A/C Variants that Cause Lipodystrophy. Journal of Lipid Research. PMID 27845687 DOI: 10.1194/jlr.M071381  0.72
2016 Shin JY, Méndez-López I, Hong M, Wang Y, Tanji K, Wu W, Shugol L, Krauss RS, Dauer WT, Worman HJ. Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth. Human Molecular Genetics. PMID 27798115 DOI: 10.1093/hmg/ddw368  0.72
2016 Chatzifrangkeskou M, Le Dour C, Wu W, Morrow JP, Joseph LC, Beuvin M, Sera F, Homma S, Vignier N, Mougenot N, Bonne G, Lipson KE, Worman HJ, Muchir A. ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene. Human Molecular Genetics. PMID 27131347 DOI: 10.1093/hmg/ddw090  1
2016 Wang Y, Lichter-Konecki U, Anyane-Yeboa K, Shaw JE, Lu JT, Östlund C, Shin JY, Clark LN, Gundersen GG, Nagy PL, Worman HJ. Mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorder. Journal of Cell Science. PMID 27034136 DOI: 10.1242/jcs.187302  1
2016 Wu W, Patel A, Kyöstilä K, Lohi H, Mladkova N, Kiryluk K, Sun X, Lefkowitch JH, Worman HJ, Gharavi AG. Genome-wide Association Study in Mice Identifies Loci Affecting Liver-related Phenotypes Including Sel1l Influencing Serum Bile Acids. Hepatology (Baltimore, Md.). PMID 26857093 DOI: 10.1002/hep.28495  1
2016 Muchir A, Worman HJ. Targeting Mitogen-Activated Protein Kinase Signaling in Mouse Models of Cardiomyopathy Caused by Lamin A/C Gene Mutations. Methods in Enzymology. 568: 557-80. PMID 26795484 DOI: 10.1016/bs.mie.2015.07.028  1
2016 Herrada I, Bourgeois B, Samson C, Buendia B, Worman HJ, Zinn-Justin S. Purification and Structural Analysis of LEM-Domain Proteins. Methods in Enzymology. 569: 43-61. PMID 26778552 DOI: 10.1016/bs.mie.2015.07.008  1
2015 Herrada I, Samson C, Velours C, Renault L, Östlund C, Chervy P, Puchkov D, Worman HJ, Buendia B, Zinn-Justin S. Muscular Dystrophy Mutations Impair the Nuclear Envelope Emerin Self-assembly Properties. Acs Chemical Biology. PMID 26415001 DOI: 10.1021/acschembio.5b00648  1
2015 Worman HJ, Schirmer EC. Nuclear membrane diversity: underlying tissue-specific pathologies in disease? Current Opinion in Cell Biology. 34: 101-12. PMID 26115475 DOI: 10.1016/j.ceb.2015.06.003  1
2015 Araujo JL, Worman HJ. Acute liver injury associated with a newer formulation of the herbal weight loss supplement Hydroxycut. Bmj Case Reports. 2015. PMID 25948859 DOI: 10.1136/bcr-2015-210303  1
2015 Chang W, Antoku S, Östlund C, Worman HJ, Gundersen GG. Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts. Nucleus (Austin, Tex.). 6: 77-88. PMID 25587885 DOI: 10.1080/19491034.2015.1004947  1
2015 Chang W, Worman HJ, Gundersen GG. Accessorizing and anchoring the LINC complex for multifunctionality. The Journal of Cell Biology. 208: 11-22. PMID 25559183 DOI: 10.1083/jcb.201409047  1
2015 Adebola AA, Di Castri T, He CZ, Salvatierra LA, Zhao J, Brown K, Lin CS, Worman HJ, Liem RK. Neurofilament light polypeptide gene N98S mutation in mice leads to neurofilament network abnormalities and a Charcot-Marie-Tooth Type 2E phenotype. Human Molecular Genetics. 24: 2163-74. PMID 25552649 DOI: 10.1093/hmg/ddu736  1
2014 Lindenboim L, Sasson T, Worman HJ, Borner C, Stein R. Cellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein release. Nucleus (Austin, Tex.). 5: 527-41. PMID 25482068 DOI: 10.4161/19491034.2014.970105  1
2014 Chang EB, Guandalini S, Rao MC, Sellin JH, Semrad CE, Worman H. Michael Field, MD (1933-2014). Gastroenterology. 147: 1191-2. PMID 25449022 DOI: 10.1053/j.gastro.2014.10.026  1
2014 Muchir A, Wu W, Sera F, Homma S, Worman HJ. Mitogen-activated protein kinase kinase 1/2 inhibition and angiotensin II converting inhibition in mice with cardiomyopathy caused by lamin A/C gene mutation. Biochemical and Biophysical Research Communications. 452: 958-61. PMID 25218145 DOI: 10.1016/j.bbrc.2014.09.020  1
2014 Meinke P, Mattioli E, Haque F, Antoku S, Columbaro M, Straatman KR, Worman HJ, Gundersen GG, Lattanzi G, Wehnert M, Shackleton S. Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization. Plos Genetics. 10: e1004605. PMID 25210889 DOI: 10.1371/journal.pgen.1004605  1
2014 Worman HJ, Dauer WT. The nuclear envelope: an intriguing focal point for neurogenetic disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 764-72. PMID 25119890 DOI: 10.1007/s13311-014-0296-8  1
2014 Shin JY, Le Dour C, Sera F, Iwata S, Homma S, Joseph LC, Morrow JP, Dauer WT, Worman HJ. Depletion of lamina-associated polypeptide 1 from cardiomyocytes causes cardiac dysfunction in mice. Nucleus (Austin, Tex.). 5: 260-459. PMID 24859316 DOI: 10.4161/nucl.29227  1
2014 Choi JC, Worman HJ. Nuclear envelope regulation of signaling cascades. Advances in Experimental Medicine and Biology. 773: 187-206. PMID 24563349 DOI: 10.1007/978-1-4899-8032-8_9  1
2014 Shin JY, Dauer WT, Worman HJ. Lamina-associated polypeptide 1: protein interactions and tissue-selective functions. Seminars in Cell & Developmental Biology. 29: 164-8. PMID 24508913 DOI: 10.1016/j.semcdb.2014.01.010  1
2014 Wu W, Iwata S, Homma S, Worman HJ, Muchir A. Depletion of extracellular signal-regulated kinase 1 in mice with cardiomyopathy caused by lamin A/C gene mutation partially prevents pathology before isoenzyme activation. Human Molecular Genetics. 23: 1-11. PMID 23933734 DOI: 10.1093/hmg/ddt387  1
2013 Chang W, Folker ES, Worman HJ, Gundersen GG. Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts. Molecular Biology of the Cell. 24: 3869-80. PMID 24152738 DOI: 10.1091/mbc.E13-06-0307  1
2013 Shin JY, Méndez-López I, Wang Y, Hays AP, Tanji K, Lefkowitch JH, Schulze PC, Worman HJ, Dauer WT. Lamina-associated polypeptide-1 interacts with the muscular dystrophy protein emerin and is essential for skeletal muscle maintenance. Developmental Cell. 26: 591-603. PMID 24055652 DOI: 10.1016/j.devcel.2013.08.012  1
2013 Muchir A, Kim YJ, Reilly SA, Wu W, Choi JC, Worman HJ. Inhibition of extracellular signal-regulated kinase 1/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutation. Skeletal Muscle. 3: 17. PMID 23815988 DOI: 10.1186/2044-5040-3-17  1
2013 Bourgeois B, Gilquin B, Tellier-Lebègue C, Östlund C, Wu W, Pérez J, El Hage P, Lallemand F, Worman HJ, Zinn-Justin S. Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A. Science Signaling. 6: ra49. PMID 23779087 DOI: 10.1126/scisignal.2003411  1
2013 Gundersen GG, Worman HJ. Nuclear positioning. Cell. 152: 1376-89. PMID 23498944 DOI: 10.1016/j.cell.2013.02.031  1
2013 Worman HJ, Segil N. Nucleocytoplasmic connections and deafness. The Journal of Clinical Investigation. 123: 553-5. PMID 23348730 DOI: 10.1172/JCI67454  1
2013 Singh M, Hunt CR, Pandita RK, Kumar R, Yang CR, Horikoshi N, Bachoo R, Serag S, Story MD, Shay JW, Powell SN, Gupta A, Jeffery J, Pandita S, Chen BP, ... ... Worman HJ, et al. Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest. Molecular and Cellular Biology. 33: 1210-22. PMID 23319047 DOI: 10.1128/MCB.01676-12  1
2013 Choi JC, Worman HJ. Reactivation of autophagy ameliorates LMNA cardiomyopathy. Autophagy. 9: 110-1. PMID 23044536 DOI: 10.4161/auto.22403  1
2012 Choi JC, Wu W, Muchir A, Iwata S, Homma S, Worman HJ. Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation. The Journal of Biological Chemistry. 287: 40513-24. PMID 23048029 DOI: 10.1074/jbc.M112.404541  1
2012 Frock RL, Chen SC, Da DF, Frett E, Lau C, Brown C, Pak DN, Wang Y, Muchir A, Worman HJ, Santana LF, Ladiges WC, Rabinovitch PS, Kennedy BK. Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice. Plos One. 7: e42918. PMID 22905185 DOI: 10.1371/journal.pone.0042918  1
2012 Wang Y, Ostlund C, Choi JC, Swayne TC, Gundersen GG, Worman HJ. Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins. Nucleus (Austin, Tex.). 3: 452-62. PMID 22895092 DOI: 10.4161/nucl.21675  1
2012 Choi JC, Muchir A, Wu W, Iwata S, Homma S, Morrow JP, Worman HJ. Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation. Science Translational Medicine. 4: 144ra102. PMID 22837537 DOI: 10.1126/scitranslmed.3003875  1
2012 Muchir A, Wu W, Choi JC, Iwata S, Morrow J, Homma S, Worman HJ. Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation. Human Molecular Genetics. 21: 4325-33. PMID 22773734 DOI: 10.1093/hmg/dds265  1
2012 Yang CY, Leung PS, Yang GX, Kenny TP, Zhang W, Coppel R, Norman GL, Ansari AA, Mackay IR, Worman HJ, Gershwin ME. Epitope-specific anti-nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine-dependent. Clinical and Experimental Immunology. 168: 261-7. PMID 22519587 DOI: 10.1111/j.1365-2249.2012.04577.x  1
2012 Duarte-Rey C, Bogdanos D, Yang CY, Roberts K, Leung PS, Anaya JM, Worman HJ, Gershwin ME. Primary biliary cirrhosis and the nuclear pore complex. Autoimmunity Reviews. 11: 898-902. PMID 22487189 DOI: 10.1016/j.autrev.2012.03.005  1
2012 Méndez-López I, Worman HJ. Inner nuclear membrane proteins: impact on human disease. Chromosoma. 121: 153-67. PMID 22307332 DOI: 10.1007/s00412-012-0360-2  1
2012 Attur M, Ben-Artzi A, Yang Q, Al-Mussawir HE, Worman HJ, Palmer G, Abramson SB. Perturbation of nuclear lamin A causes cell death in chondrocytes. Arthritis and Rheumatism. 64: 1940-9. PMID 22231515 DOI: 10.1002/art.34360  1
2012 Muchir A, Reilly SA, Wu W, Iwata S, Homma S, Bonne G, Worman HJ. Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene. Cardiovascular Research. 93: 311-9. PMID 22068161 DOI: 10.1093/cvr/cvr301  1
2012 Worman HJ. Nuclear lamins and laminopathies. The Journal of Pathology. 226: 316-25. PMID 21953297 DOI: 10.1002/path.2999  1
2011 Duband-Goulet I, Woerner S, Gasparini S, Attanda W, Kondé E, Tellier-Lebègue C, Craescu CT, Gombault A, Roussel P, Vadrot N, Vicart P, Ostlund C, Worman HJ, Zinn-Justin S, Buendia B. Subcellular localization of SREBP1 depends on its interaction with the C-terminal region of wild-type and disease related A-type lamins. Experimental Cell Research. 317: 2800-13. PMID 21993218 DOI: 10.1016/j.yexcr.2011.09.012  1
2011 Luxton GW, Gomes ER, Folker ES, Worman HJ, Gundersen GG. TAN lines: a novel nuclear envelope structure involved in nuclear positioning. Nucleus (Austin, Tex.). 2: 173-81. PMID 21818410 DOI: 10.4161/nucl.2.3.16243  1
2011 Lu JT, Muchir A, Nagy PL, Worman HJ. LMNA cardiomyopathy: cell biology and genetics meet clinical medicine. Disease Models & Mechanisms. 4: 562-8. PMID 21810905 DOI: 10.1242/dmm.006346  1
2011 Rong G, Zhong R, Lleo A, Leung PS, Bowlus CL, Yang GX, Yang CY, Coppel RL, Ansari AA, Cuebas DA, Worman HJ, Invernizzi P, Gores GJ, Norman G, He XS, et al. Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis. Hepatology (Baltimore, Md.). 54: 196-203. PMID 21488079 DOI: 10.1002/hep.24355  1
2011 Wu W, Muchir A, Shan J, Bonne G, Worman HJ. Mitogen-activated protein kinase inhibitors improve heart function and prevent fibrosis in cardiomyopathy caused by mutation in lamin A/C gene. Circulation. 123: 53-61. PMID 21173351 DOI: 10.1161/CIRCULATIONAHA.110.970673  1
2011 Folker ES, Ostlund C, Luxton GW, Worman HJ, Gundersen GG. Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement. Proceedings of the National Academy of Sciences of the United States of America. 108: 131-6. PMID 21173262 DOI: 10.1073/pnas.1000824108  1
2010 Muchir A, Wu W, Worman HJ. Mitogen-activated protein kinase inhibitor regulation of heart function and fibrosis in cardiomyopathy caused by lamin A/C gene mutation. Trends in Cardiovascular Medicine. 20: 217-21. PMID 22293021 DOI: 10.1016/j.tcm.2011.11.002  1
2010 Wang Y, Ostlund C, Worman HJ. Blocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndrome. Nucleus (Austin, Tex.). 1: 432-9. PMID 21326826 DOI: 10.4161/nucl.1.5.12972  1
2010 Liu H, Norman GL, Shums Z, Worman HJ, Krawitt EL, Bizzaro N, Vergani D, Bogdanos DP, Dalekos GN, Milkiewicz P, Czaja AJ, Heathcote EJ, Hirschfield GM, Tan EM, Miyachi K, et al. PBC screen: an IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis. Journal of Autoimmunity. 35: 436-42. PMID 20932720 DOI: 10.1016/j.jaut.2010.09.005  1
2010 Muchir A, Worman HJ. Signaling defects and the nuclear envelope in progeria. Developmental Cell. 19: 355-6. PMID 20833355 DOI: 10.1016/j.devcel.2010.08.019  1
2010 Kondé E, Bourgeois B, Tellier-Lebegue C, Wu W, Pérez J, Caputo S, Attanda W, Gasparini S, Charbonnier JB, Gilquin B, Worman HJ, Zinn-Justin S. Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane. Biochemistry. 49: 8020-32. PMID 20715792 DOI: 10.1021/bi101153w  1
2010 Dorval T, Ogier A, Genovesio A, Lim HK, Kwon do Y, Lee JH, Worman HJ, Dauer W, Grailhe R. Contextual automated 3D analysis of subcellular organelles adapted to high-content screening. Journal of Biomolecular Screening. 15: 847-57. PMID 20639502 DOI: 10.1177/1087057110374993  1
2010 Bruston F, Delbarre E, Ostlund C, Worman HJ, Buendia B, Duband-Goulet I. Loss of a DNA binding site within the tail of prelamin A contributes to altered heterochromatin anchorage by progerin. Febs Letters. 584: 2999-3004. PMID 20580717 DOI: 10.1016/j.febslet.2010.05.032  1
2010 Lleo A, Bowlus CL, Yang GX, Invernizzi P, Podda M, Van de Water J, Ansari AA, Coppel RL, Worman HJ, Gores GJ, Gershwin ME. Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis. Hepatology (Baltimore, Md.). 52: 987-98. PMID 20568301 DOI: 10.1002/hep.23783  1
2010 Marji J, O'Donoghue SI, McClintock D, Satagopam VP, Schneider R, Ratner D, Worman HJ, Gordon LB, Djabali K. Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition. Plos One. 5: e11132. PMID 20559568 DOI: 10.1371/journal.pone.0011132  1
2010 Lüdtke A, Roos GM, van Hettinga M, Horst BA, Worman HJ, Schmidt HH. Post-mortem findings in Dunnigan-type familial partial lipodystrophy. Diabetic Medicine : a Journal of the British Diabetic Association. 27: 245-6. PMID 20546275 DOI: 10.1111/j.1464-5491.2009.02909.x  1
2010 Wu W, Shan J, Bonne G, Worman HJ, Muchir A. Pharmacological inhibition of c-Jun N-terminal kinase signaling prevents cardiomyopathy caused by mutation in LMNA gene. Biochimica Et Biophysica Acta. 1802: 632-8. PMID 20388542 DOI: 10.1016/j.bbadis.2010.04.001  1
2010 Dauer WT, Worman HJ. New messages in the nuclear envelope. Cell Cycle (Georgetown, Tex.). 9: 645-6. PMID 20190576  1
2010 Worman HJ, Ostlund C, Wang Y. Diseases of the nuclear envelope. Cold Spring Harbor Perspectives in Biology. 2: a000760. PMID 20182615 DOI: 10.1101/cshperspect.a000760  1
2010 Worman HJ, Foisner R. The nuclear envelope from basic biology to therapy. Biochemical Society Transactions. 38: 253-6. PMID 20074069 DOI: 10.1042/BST0380253  1
2010 Worman HJ. Prelamin A prenylation and the treatment of progeria. Journal of Lipid Research. 51: 223-5. PMID 19965579 DOI: 10.1194/jlr.E004366  1
2009 Dauer WT, Worman HJ. The nuclear envelope as a signaling node in development and disease. Developmental Cell. 17: 626-38. PMID 19922868 DOI: 10.1016/j.devcel.2009.10.016  1
2009 Ostlund C, Folker ES, Choi JC, Gomes ER, Gundersen GG, Worman HJ. Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins. Journal of Cell Science. 122: 4099-108. PMID 19843581 DOI: 10.1242/jcs.057075  1
2009 Ostlund C, Guan T, Figlewicz DA, Hays AP, Worman HJ, Gerace L, Schirmer EC. Reduction of a 4q35-encoded nuclear envelope protein in muscle differentiation. Biochemical and Biophysical Research Communications. 389: 279-83. PMID 19716805 DOI: 10.1016/j.bbrc.2009.08.133  1
2009 Worman HJ, Fong LG, Muchir A, Young SG. Laminopathies and the long strange trip from basic cell biology to therapy. The Journal of Clinical Investigation. 119: 1825-36. PMID 19587457 DOI: 10.1172/JCI37679  1
2009 Verstraeten VL, Caputo S, van Steensel MA, Duband-Goulet I, Zinn-Justin S, Kamps M, Kuijpers HJ, Ostlund C, Worman HJ, Briedé JJ, Le Dour C, Marcelis CL, van Geel M, Steijlen PM, van den Wijngaard A, et al. The R439C mutation in LMNA causes lamin oligomerization and susceptibility to oxidative stress. Journal of Cellular and Molecular Medicine. 13: 959-71. PMID 19220582 DOI: 10.1111/j.1582-4934.2009.00690.x  1
2009 Muchir A, Wu W, Worman HJ. Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells. Biochimica Et Biophysica Acta. 1792: 75-81. PMID 19022376 DOI: 10.1016/j.bbadis.2008.10.012  1
2009 Muchir A, Shan J, Bonne G, Lehnart SE, Worman HJ. Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins. Human Molecular Genetics. 18: 241-7. PMID 18927124 DOI: 10.1093/hmg/ddn343  1
2008 Wang Y, Panteleyev AA, Owens DM, Djabali K, Stewart CL, Worman HJ. Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin. Human Molecular Genetics. 17: 2357-69. PMID 18442998 DOI: 10.1093/hmg/ddn136  1
2007 Selmi C, Gershwin ME, Lindor KD, Worman HJ, Gold EB, Watnik M, Utts J, Invernizzi P, Kaplan MM, Vierling JM, Bowlus CL, Silveira MG, Bossi I. Quality of life and everyday activities in patients with primary biliary cirrhosis. Hepatology (Baltimore, Md.). 46: 1836-43. PMID 18027862 DOI: 10.1002/hep.21953  1
2007 Worman HJ. Nuclear envelope protein autoantigens in primary biliary cirrhosis. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 37: S406-11. PMID 17931195 DOI: 10.1111/j.1872-034X.2007.00227.x  1
2007 Worman HJ. Re-evaluating the use of growth factors as adjuvant treatment of chronic hepatitis C. Hepatology (Baltimore, Md.). 46: 1307-8; author reply. PMID 17894319 DOI: 10.1002/hep.21824  1
2007 Lüdtke A, Buettner J, Schmidt HH, Worman HJ. New PPARG mutation leads to lipodystrophy and loss of protein function that is partially restored by a synthetic ligand. Journal of Medical Genetics. 44: e88. PMID 17766367 DOI: 10.1136/jmg.2007.050567  1
2007 Muchir A, Pavlidis P, Bonne G, Hayashi YK, Worman HJ. Activation of MAPK in hearts of EMD null mice: similarities between mouse models of X-linked and autosomal dominant Emery Dreifuss muscular dystrophy. Human Molecular Genetics. 16: 1884-95. PMID 17567779 DOI: 10.1093/hmg/ddm137  1
2007 Worman HJ, Bonne G. "Laminopathies": a wide spectrum of human diseases. Experimental Cell Research. 313: 2121-33. PMID 17467691 DOI: 10.1016/j.yexcr.2007.03.028  1
2007 Muchir A, Pavlidis P, Decostre V, Herron AJ, Arimura T, Bonne G, Worman HJ. Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy. The Journal of Clinical Investigation. 117: 1282-93. PMID 17446932 DOI: 10.1172/JCI29042  1
2007 Lüdtke A, Buettner J, Wu W, Muchir A, Schroeter A, Zinn-Justin S, Spuler S, Schmidt HH, Worman HJ. Peroxisome proliferator-activated receptor-gamma C190S mutation causes partial lipodystrophy. The Journal of Clinical Endocrinology and Metabolism. 92: 2248-55. PMID 17356052 DOI: 10.1210/jc.2005-2624  1
2007 Muchir A, Worman HJ. Emery-Dreifuss muscular dystrophy. Current Neurology and Neuroscience Reports. 7: 78-83. PMID 17217858 DOI: 10.1007/s11910-007-0025-3  1
2006 Muchir A, Massart C, van Engelen BG, Lammens M, Bonne G, Worman HJ. Proteasome-mediated degradation of integral inner nuclear membrane protein emerin in fibroblasts lacking A-type lamins. Biochemical and Biophysical Research Communications. 351: 1011-7. PMID 17097067 DOI: 10.1016/j.bbrc.2006.10.147  1
2006 Wang Y, Herron AJ, Worman HJ. Pathology and nuclear abnormalities in hearts of transgenic mice expressing M371K lamin A encoded by an LMNA mutation causing Emery-Dreifuss muscular dystrophy. Human Molecular Genetics. 15: 2479-89. PMID 16825283 DOI: 10.1093/hmg/ddl170  1
2006 Caputo S, Couprie J, Duband-Goulet I, Kondé E, Lin F, Braud S, Gondry M, Gilquin B, Worman HJ, Zinn-Justin S. The carboxyl-terminal nucleoplasmic region of MAN1 exhibits a DNA binding winged helix domain. The Journal of Biological Chemistry. 281: 18208-15. PMID 16648637 DOI: 10.1074/jbc.M601980200  1
2006 Wesierska-Gadek J, Penner E, Battezzati PM, Selmi C, Zuin M, Hitchman E, Worman HJ, Gershwin ME, Podda M, Invernizzi P. Correlation of initial autoantibody profile and clinical outcome in primary biliary cirrhosis. Hepatology (Baltimore, Md.). 43: 1135-44. PMID 16628641 DOI: 10.1002/hep.21172  1
2006 Caputo S, Lin F, Gilquin B, Worman HJ, Zinn-Justin S, Couprie J. NMR assignment of region 655-775 of human MAN1. Journal of Biomolecular Nmr. 36: 2. PMID 16601860 DOI: 10.1007/s10858-005-2628-9  1
2006 Worman HJ. Inner nuclear membrane and regulation of Smad-mediated signaling. Biochimica Et Biophysica Acta. 1761: 626-31. PMID 16574476 DOI: 10.1016/j.bbalip.2006.02.010  1
2006 Ostlund C, Sullivan T, Stewart CL, Worman HJ. Dependence of diffusional mobility of integral inner nuclear membrane proteins on A-type lamins. Biochemistry. 45: 1374-82. PMID 16445279 DOI: 10.1021/bi052156n  1
2006 Boguslavsky RL, Stewart CL, Worman HJ. Nuclear lamin A inhibits adipocyte differentiation: implications for Dunnigan-type familial partial lipodystrophy. Human Molecular Genetics. 15: 653-63. PMID 16415042 DOI: 10.1093/hmg/ddi480  1
2006 Worman HJ, Gundersen GG. Here come the SUNs: a nucleocytoskeletal missing link. Trends in Cell Biology. 16: 67-9. PMID 16406617 DOI: 10.1016/j.tcb.2005.12.006  1
2005 Gershwin ME, Selmi C, Worman HJ, Gold EB, Watnik M, Utts J, Lindor KD, Kaplan MM, Vierling JM. Risk factors and comorbidities in primary biliary cirrhosis: a controlled interview-based study of 1032 patients. Hepatology (Baltimore, Md.). 42: 1194-202. PMID 16250040 DOI: 10.1002/hep.20907  1
2005 Lüdtke A, Heck K, Genschel J, Mehnert H, Spuler S, Worman HJ, Schmidt HH. Long-term treatment experience in a subject with Dunnigan-type familial partial lipodystrophy: efficacy of rosiglitazone. Diabetic Medicine : a Journal of the British Diabetic Association. 22: 1611-3. PMID 16241930 DOI: 10.1111/j.1464-5491.2005.01757.x  1
2005 Worman HJ. Inner nuclear membrane and signal transduction. Journal of Cellular Biochemistry. 96: 1185-92. PMID 16211582 DOI: 10.1002/jcb.20650  1
2005 Lüdtke A, Genschel J, Brabant G, Bauditz J, Taupitz M, Koch M, Wermke W, Worman HJ, Schmidt HH. Hepatic steatosis in Dunnigan-type familial partial lipodystrophy. The American Journal of Gastroenterology. 100: 2218-24. PMID 16181372 DOI: 10.1111/j.1572-0241.2005.00234.x  1
2005 Worman HJ, Courvalin JC. Nuclear envelope, nuclear lamina, and inherited disease. International Review of Cytology. 246: 231-79. PMID 16164970 DOI: 10.1016/S0074-7696(05)46006-4  1
2005 Paradisi M, McClintock D, Boguslavsky RL, Pedicelli C, Worman HJ, Djabali K. Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress. Bmc Cell Biology. 6: 27. PMID 15982412 DOI: 10.1186/1471-2121-6-27  1
2005 Worman HJ. Components of the nuclear envelope and their role in human disease. Novartis Foundation Symposium. 264: 35-42; discussion 42. PMID 15773746  1
2005 Broers JL, Kuijpers HJ, Ostlund C, Worman HJ, Endert J, Ramaekers FC. Both lamin A and lamin C mutations cause lamina instability as well as loss of internal nuclear lamin organization. Experimental Cell Research. 304: 582-92. PMID 15748902 DOI: 10.1016/j.yexcr.2004.11.020  1
2005 Ostlund C, Garcia-Carrasquillo RM, Belayew A, Worman HJ. Intracellular trafficking and dynamics of double homeodomain proteins. Biochemistry. 44: 2378-84. PMID 15709750 DOI: 10.1021/bi047992w  1
2005 Lin F, Morrison JM, Wu W, Worman HJ. MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling. Human Molecular Genetics. 14: 437-45. PMID 15601644 DOI: 10.1093/hmg/ddi040  1
2005 Warner HR, Goldman A, Goldman RD, Capeau J, Hutchison C, Bonne G, Gruenbaum Y, Morris GE, Stewart CL, Worman HJ, Burke B, Gerace L, Young SG, Wilkins A, Wilson KL. Discussion Novartis Foundation Symposium. 264: 16-21.  1
2005 Fatkin D, Wilson KL, Gruenbaum Y, Ellis J, Julien JP, Shumaker D, Goldman A, Morris GE, Gerace L, Wilkins A. Discussion Novartis Foundation Symposium. 264: 58-62.  0.32
2004 Ostlund C, Worman HJ. Lamin-associated proteins. Methods in Cell Biology. 78: 829-59. PMID 15646641  1
2004 Gilchrist S, Gilbert N, Perry P, Ostlund C, Worman HJ, Bickmore WA. Altered protein dynamics of disease-associated lamin A mutants. Bmc Cell Biology. 5: 46. PMID 15596010 DOI: 10.1186/1471-2121-5-46  1
2004 Worman HJ. Nuclear envelope proteins and human disease. Symposia of the Society For Experimental Biology. 41-55. PMID 15565874  1
2004 Hutchison CJ, Worman HJ. A-type lamins: guardians of the soma? Nature Cell Biology. 6: 1062-7. PMID 15517000 DOI: 10.1038/ncb1104-1062  1
2004 Bergasa NV, Mason A, Floreani A, Heathcote J, Swain MG, Jones DE, Lindor KM, Bassendine MF, Worman HJ. Primary biliary cirrhosis: report of a focus study group. Hepatology (Baltimore, Md.). 40: 1013-20. PMID 15382160 DOI: 10.1002/hep.20446  1
2004 Muchir A, Worman HJ. The nuclear envelope and human disease. Physiology (Bethesda, Md.). 19: 309-14. PMID 15381760 DOI: 10.1152/physiol.00022.2004  1
2004 Muchir A, Medioni J, Laluc M, Massart C, Arimura T, van der Kooi AJ, Desguerre I, Mayer M, Ferrer X, Briault S, Hirano M, Worman HJ, Mallet A, Wehnert M, Schwartz K, et al. Nuclear envelope alterations in fibroblasts from patients with muscular dystrophy, cardiomyopathy, and partial lipodystrophy carrying lamin A/C gene mutations. Muscle & Nerve. 30: 444-50. PMID 15372542 DOI: 10.1002/mus.20122  1
2004 Verna EC, Larghi A, Faddoul SG, Stein JA, Worman HJ. Portal vein thrombosis associated with Fusobacterium nucleatum septicemia in a patient with ulcerative colitis. Journal of Clinical Gastroenterology. 38: 611-2. PMID 15232367 DOI: 10.1097/00004836-200408000-00014  1
2004 Worman HJ, Courvalin JC. How do mutations in lamins A and C cause disease? The Journal of Clinical Investigation. 113: 349-51. PMID 14755330 DOI: 10.1172/JCI20832  1
2003 Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Molecular and Cellular Biology. 23: 8363-76. PMID 14585993 DOI: 10.1128/MCB.23.22.8363-8376.2003  1
2003 Worman HJ, Courvalin JC. Antinuclear antibodies specific for primary biliary cirrhosis. Autoimmunity Reviews. 2: 211-7. PMID 12848948 DOI: 10.1016/S1568-9972(03)00013-2  1
2003 Shimoda S, Nakamura M, Ishibashi H, Kawano A, Kamihira T, Sakamoto N, Matsushita S, Tanaka A, Worman HJ, Gershwin ME, Harada M. Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis. Gastroenterology. 124: 1915-25. PMID 12806624 DOI: 10.1016/S0016-5085(03)00387-1  1
2003 Holt I, Ostlund C, Stewart CL, Man Nt, Worman HJ, Morris GE. Effect of pathogenic mis-sense mutations in lamin A on its interaction with emerin in vivo. Journal of Cell Science. 116: 3027-35. PMID 12783988 DOI: 10.1242/jcs.00599  1
2003 Stierlé V, Couprie J, Ostlund C, Krimm I, Zinn-Justin S, Hossenlopp P, Worman HJ, Courvalin JC, Duband-Goulet I. The carboxyl-terminal region common to lamins A and C contains a DNA binding domain. Biochemistry. 42: 4819-28. PMID 12718522 DOI: 10.1021/bi020704g  1
2003 Ostlund C, Worman HJ. Nuclear envelope proteins and neuromuscular diseases. Muscle & Nerve. 27: 393-406. PMID 12661041 DOI: 10.1002/mus.10302  1
2003 Larghi A, Leffler D, Frucht H, Rubin M, Semrad CE, Lefkowitch JH, Worman HJ. Hepatitis B virus reactivation after kidney transplantation and new onset lymphoma. Journal of Clinical Gastroenterology. 36: 276-80. PMID 12590243 DOI: 10.1097/00004836-200303000-00018  1
2003 Favreau C, Dubosclard E, Ostlund C, Vigouroux C, Capeau J, Wehnert M, Higuet D, Worman HJ, Courvalin JC, Buendia B. Expression of lamin A mutated in the carboxyl-terminal tail generates an aberrant nuclear phenotype similar to that observed in cells from patients with Dunnigan-type partial lipodystrophy and Emery-Dreifuss muscular dystrophy. Experimental Cell Research. 282: 14-23. PMID 12490190 DOI: 10.1006/excr.2002.5669  1
2002 Worman HJ, Courvalin JC. The nuclear lamina and inherited disease. Trends in Cell Biology. 12: 591-8. PMID 12495848 DOI: 10.1016/S0962-8924(02)02401-7  1
2002 Parikh-Patel A, Gold EB, Utts J, Worman H, Krivy KE, Gershwin ME. Functional status of patients with primary biliary cirrhosis. The American Journal of Gastroenterology. 97: 2871-9. PMID 12425562 DOI: 10.1111/j.1572-0241.2002.07055.x  1
2002 Dettmer RM, Reinus JF, Clain DJ, Aytaman A, Levendoglu H, Bloom AA, Isaacson MP, Spinnell M, Meyer D, Sarabanchong V, Zhang Y, Garcia-Carrasquillo RJ, Markowitz DD, Magun AM, Worman HJ. Interferon-alpha-2b and ribavirin for retreatment of chronic hepatitis C. Hepato-Gastroenterology. 49: 758-63. PMID 12063985  1
2002 Krimm I, Ostlund C, Gilquin B, Couprie J, Hossenlopp P, Mornon JP, Bonne G, Courvalin JC, Worman HJ, Zinn-Justin S. The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy. Structure (London, England : 1993). 10: 811-23. PMID 12057196 DOI: 10.1016/S0969-2126(02)00777-3  1
2002 Hwang KK, Worman HJ. Gene regulation by human orthologs of Drosophila heterochromatin protein 1. Biochemical and Biophysical Research Communications. 293: 1217-22. PMID 12054505 DOI: 10.1016/S0006-291X(02)00377-7  1
2002 Krimm I, Couprie J, Ostlund C, Worman HJ, Zinn-Justin S. 1H, 13C and 15N resonance assignments of the C-terminal domain of human lamin A/C. Journal of Biomolecular Nmr. 22: 371-2. PMID 12018485 DOI: 10.1023/A:1014943122068  1
2002 Wu W, Lin F, Worman HJ. Intracellular trafficking of MAN1, an integral protein of the nuclear envelope inner membrane. Journal of Cell Science. 115: 1361-71. PMID 11896184  1
2002 Bonne G, Capeau J, De Visser M, Duboc D, Merlini L, Morris GE, Muntoni F, Recan D, Sewry C, Squarzoni S, Stewart C, Talim B, van der Kooi A, Worman H, Schwartz K. 82nd ENMC international workshop, 5th international Emery-Dreifuss muscular dystrophy (EDMD) workshop, 1st Workshop of the MYO-CLUSTER project EUROMEN (European muscle envelope nucleopathies), 15-16 September 2000, Naarden, The Netherlands. Neuromuscular Disorders : Nmd. 12: 187-94. PMID 11738362 DOI: 10.1016/S0960-8966(01)00243-7  1
2001 Ostlund C, Bonne G, Schwartz K, Worman HJ. Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy. Journal of Cell Science. 114: 4435-45. PMID 11792809  1
2001 Holmer L, Worman HJ. Inner nuclear membrane proteins: functions and targeting. Cellular and Molecular Life Sciences : Cmls. 58: 1741-7. PMID 11766875  1
2001 Terjung B, Worman HJ, Herzog V, Sauerbruch T, Spengler U. Differentiation of antineutrophil nuclear antibodies in inflammatory bowel and autoimmune liver diseases from antineutrophil cytoplasmic antibodies (p-ANCA) using immunofluorescence microscopy. Clinical and Experimental Immunology. 126: 37-46. PMID 11678897 DOI: 10.1046/j.1365-2249.2001.01649.x  1
2001 Hwang KK, Eissenberg JC, Worman HJ. Transcriptional repression of euchromatic genes by Drosophila heterochromatin protein 1 and histone modifiers. Proceedings of the National Academy of Sciences of the United States of America. 98: 11423-7. PMID 11562500 DOI: 10.1073/pnas.211303598  1
2001 Terjung B, Worman HJ. Anti-neutrophil antibodies in primary sclerosing cholangitis Best Practice and Research: Clinical Gastroenterology. 15: 629-642. PMID 11492972 DOI: 10.1053/bega.2001.0209  1
2001 Wolff N, Gilquin B, Courchay K, Callebaut I, Worman HJ, Zinn-Justin S. Structural analysis of emerin, an inner nuclear membrane protein mutated in X-linked Emery-Dreifuss muscular dystrophy Febs Letters. 501: 171-176. PMID 11470279  1
2001 Laguri C, Gilquin B, Wolff N, Romi-Lebrun R, Courchay K, Callebaut I, Worman HJ, Zinn-Justin S. Structural characterization of the LEM motif common to three human inner nuclear membrane proteins Structure. 9: 503-511. PMID 11435115 DOI: 10.1016/S0969-2126(01)00611-6  1
2001 Ma J, Hwang KK, Worman HJ, Courvalin JC, Eissenberg JC. Expression and functional analysis of three isoforms of human heterochromatin-associated protein HP1 in Drosophila. Chromosoma. 109: 536-44. PMID 11305786  1
2001 Wilson KL, Benavente R, Burke B, Craigie R, Foisner R, Furukawa K, Gerace L, Goldman RD, Gruenbaum Y, Harris C, Hutchison CJ, Krohne G, Morris GE, Otto H, Simon AJ, ... Worman HJ, et al. Problems with LAP nomenclature. Nature Cell Biology. 3: E90. PMID 11283624 DOI: 10.1038/35070147  1
2001 Parikh-Patel A, Gold EB, Worman H, Krivy KE, Gershwin ME. Risk factors for primary biliary cirrhosis in a cohort of patients from the United States Hepatology. 33: 16-21. PMID 11124815 DOI: 10.1053/jhep.2001.21165  1
2000 Worman HJ, Courvalin JC. The inner nuclear membrane Journal of Membrane Biology. 177: 1-11. PMID 10960149 DOI: 10.1007/s002320001096  1
2000 Terjung B, Spengler U, Sauerbruch T, Worman HJ. 'Atypical p-ANCA' in IBD and hepatobiliary disorders react with a 50-kilodalton nuclear envelope protein of neutrophils and myeloid cell lines Gastroenterology. 119: 310-322. PMID 10930366  1
2000 Lin F, Blake DL, Callebaut I, Skerjanc IS, Holmer L, McBurney MW, Paulin-Levasseur M, Worman HJ. MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin Journal of Biological Chemistry. 275: 4840-4847. PMID 10671519 DOI: 10.1074/jbc.275.7.4840  1
2000 Worman HJ, Lin F. Molecular biology of liver disorders: The hepatitis C virus and molecular targets for drug development World Journal of Gastroenterology. 6: 465-469.  1
1999 Moss SF, Krivosheyev V, De Souza A, Chin K, Gaetz HP, Chaudhary N, Worman HJ, Holt PR. Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms Gut. 45: 723-729. PMID 10517909  1
1999 Barton RM, Worman HJ. Prenylated prelamin A interacts with Narf, a novel nuclear protein Journal of Biological Chemistry. 274: 30008-30018. PMID 10514485 DOI: 10.1074/jbc.274.42.30008  1
1999 Minc E, Allory Y, Worman HJ, Courvalin JC, Buendia B. Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells Chromosoma. 108: 220-234. PMID 10460410 DOI: 10.1007/s004120050372  1
1999 Pierce T, Worman HJ, Holy J. Neuronal differentiation of NT2/D1 teratocarcinoma cells is accompanied by a loss of lamin A/C expression and an increase in lamin B1 expression Experimental Neurology. 157: 241-250. PMID 10364436 DOI: 10.1006/exnr.1999.7060  1
1999 Mamiya N, Worman HJ. Hepatitis C virus core protein binds to a DEAD box RNA helicase Journal of Biological Chemistry. 274: 15751-15756. PMID 10336476 DOI: 10.1074/jbc.274.22.15751  1
1999 Östlund C, Ellenberg J, Hallberg E, Lippincott-Schwartz J, Worman HJ. Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein Journal of Cell Science. 112: 1709-1719. PMID 10318763  1
1999 Quaranta S, Shulman H, Ahmed A, Shoenfeld Y, Peter J, McDonald GB, Van de Water J, Coppel R, Ostlund C, Worman HJ, Rizzetto M, Tsuneyama K, Nakanuma Y, Ansari A, Locatelli F, et al. Autoantibodies in human chronic graft-versus-host disease after hematopoietic cell transplantation. Clinical Immunology (Orlando, Fla.). 91: 106-16. PMID 10219261 DOI: 10.1006/clim.1998.4666  1
1998 Park A, Holmer L, Worman HJ. A human HP1 pseudogene maps to chromosome 11p14 Somatic Cell and Molecular Genetics. 24: 353-356. PMID 10763413  1
1998 De La Riva E, Garcia-Carrasquillo RJ, Puppo MD, Mustacchia PJ, Factor S, Joe A, Finegold J, Riley TH, Sarabanchong V, Ligresti RJ, Markowitz DD, McMahon DJ, Magun AM, Worman HJ. Escalating interferon-a-2b dose for patients with chronic hepatitis C Hepato-Gastroenterology. 45: 2308-2314. PMID 9951914  1
1998 Ye Q, Barton RM, Worman HJ. Nuclear lamin-binding proteins. Sub-Cellular Biochemistry. 31: 587-610. PMID 9932507  1
1998 Holmer L, Pezhman A, Worman HJ. The human lamin B receptor/sterol reductase multigene family Genomics. 54: 469-476. PMID 9878250 DOI: 10.1006/geno.1998.5615  1
1998 Terjung B, Herzog V, Worman HJ, Gestmann I, Bauer C, Sauerbruch T, Spengler U. Atypical antineutrophil cytoplasmic antibodies with perinuclear fluorescence in chronic inflammatory bowel diseases and hepatobiliary disorders colocalize with nuclear lamina proteins Hepatology. 28: 332-340. PMID 9695994 DOI: 10.1002/hep.510280207  1
1998 Luettig B, Boeker KH, Schoessler W, Will H, Loges S, Schmidt E, Worman HJ, Gershwin ME, Manns MP. The antinuclear autoantibodies Sp100 and gp210 persist after orthotopic liver transplantation in patients with primary biliary cirrhosis. Journal of Hepatology. 28: 824-8. PMID 9625318 DOI: 10.1016/S0168-8278(98)80233-X  1
1997 Mattalia A, Lüttig B, Rosina F, Leung PS, Van de Water J, Bauducci M, Ciancio A, Böker KH, Worman H, Cooper RL, Manns M, Ansari A, Rizzetto M, Gershwin ME. Persistence of autoantibodies against recombinant mitochondrial and nuclear pore proteins after orthotopic liver transplantation for primary biliary cirrhosis. Journal of Autoimmunity. 10: 491-7. PMID 9376077 DOI: 10.1006/jaut.1997.0156  1
1997 Lin F, Worman HJ. Expression of nuclear lamins in human tissues and cancer cell lines and transcription from the promoters of the lamin A/C and B1 genes Experimental Cell Research. 236: 378-384. PMID 9367621 DOI: 10.1006/excr.1997.3735  1
1997 Ellenberg J, Siggia ED, Moreira JE, Smith CL, Presley JF, Worman HJ, Lippincott-Schwartz J. Nuclear membrane dynamics and reassembly in living cells: Targeting of an inner nuclear membrane protein in interphase and mitosis Journal of Cell Biology. 138: 1193-1206. PMID 9298976 DOI: 10.1083/jcb.138.6.1193  1
1997 Worman HJ. Molecular biological methods in diagnosis and treatment of liver diseases Clinical Chemistry. 43: 1476-1486. PMID 9265898  1
1997 Callebaut I, Courvalin JC, Worman HJ, Mornon JP. Hydrophobic cluster analysis reveals a third chromodomain in the tetrahymena Pdd1p protein of the chrome superfamily Biochemical and Biophysical Research Communications. 235: 103-107. PMID 9196044 DOI: 10.1006/bbrc.1997.6748  1
1997 Ye Q, Callebaut I, Pezhman A, Courvalin JC, Worman HJ. Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR. The Journal of Biological Chemistry. 272: 14983-9. PMID 9169472 DOI: 10.1074/jbc.272.23.14983  1
1997 Nishio A, Van De Water J, Leung PSC, Joplin R, Neuberger JM, Lake J, Björkland A, Tötterman TH, Peters M, Worman HJ, Ansari AA, Coppel RL, Gershwin ME. Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis Hepatology. 25: 1085-1089. PMID 9141421  1
1997 Courvalin JC, Worman HJ. Nuclear envelope protein autoantibodies in primary biliary cirrhosis Seminars in Liver Disease. 17: 79-90. PMID 9089913  1
1997 Mamiya N, Worman HJ. Epidemiology, prevention, clinical features and therapy of hepatitis B, C and G Current Opinion in Infectious Diseases. 10: 390-397. DOI: 10.1097/00001432-199710000-00013  1
1997 Mattalia A, Lutting B, Leung PSC, Bauducci M, Worman H, Ciancio A, Rosina F, Coppel RL, Manns M, Rizzetto M, Gershwin M. The influence of liver transplantation (OLT) on antibodies to mitochondria (AMA) and GP210 in primary biliary cirrhosis (PBC) Italian Journal of Gastroenterology and Hepatology. 29: 97.  1
1996 Wydner KL, McNeil JA, Lin F, Worman HJ, Lawrence JB. Chromosomal assignment of human nuclear envelope protein genes LMNA, LMNB1, and LBR by fluorescence in situ hybridization. Genomics. 32: 474-8. PMID 8838815 DOI: 10.1006/geno.1996.0146  1
1996 Yeh HC, Klion FM, Thung SN, Worman HJ. Angiomyolipoma: Ultrasonographic signs of lipomatous hepatic tumors Journal of Ultrasound in Medicine. 15: 337-342. PMID 8683672  1
1996 Favreau C, Worman HJ, Wozniak RW, Frappier T, Courvalin JC. Cell cycle-dependent phosphorylation of nucleoporins and nuclear pore membrane protein Gp210 Biochemistry. 35: 8035-8044. PMID 8672508 DOI: 10.1021/bi9600660  1
1996 Ye Q, Worman HJ. Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1. The Journal of Biological Chemistry. 271: 14653-6. PMID 8663349 DOI: 10.1074/jbc.271.25.14653  1
1996 Klein RS, Worman HJ, Shakil AO, Alter HJ. Blood donors with antibody to hepatitis C virus [5] Annals of Internal Medicine. 124: 930-931. PMID 8610936  1
1996 Lin F, Noyer CM, Ye Q, Courvalin JC, Worman HJ. Autoantibodies from patients with primary biliary cirrhosis recognize a region within the nucleoplasmic domain of inner nuclear membrane protein LBR. Hepatology (Baltimore, Md.). 23: 57-61. PMID 8550049 DOI: 10.1002/hep.510230109  1
1995 Soullam B, Worman HJ. Signals and structural features involved in integral membrane protein targeting to the inner nuclear membrane Journal of Cell Biology. 130: 15-27. PMID 7790369 DOI: 10.1083/jcb.130.1.15  1
1995 Worman HJ. Interferon-α is effective in the treatment of chronic hepatitis C [11] American Journal of Gastroenterology. 90: 679-680. PMID 7717348  1
1995 Ye Q, Worman HJ. Protein-protein interactions between human nuclear lamins expressed in yeast. Experimental Cell Research. 219: 292-8. PMID 7628545 DOI: 10.1006/excr.1995.1230  1
1995 Lin F, Worman HJ. Structural organization of the human gene (LMNB1) encoding nuclear lamin B1 Genomics. 27: 230-236. PMID 7557986 DOI: 10.1006/geno.1995.1036  1
1995 Tartakovsky F, Worman HJ. Detection of Gp210 autoantibodies in primary biliary cirrhosis using a recombinant protein containing the predominant autoepitope Hepatology. 21: 495-500. PMID 7531172 DOI: 10.1016/0270-9139(95)90112-4  1
1994 Nickowitz RE, Wozniak RW, Schaffner F, Worman HJ. Autoantibodies against integral membrane proteins of the nuclear envelope in patients with primary biliary cirrhosis Gastroenterology. 106: 193-199. PMID 8276182  1
1994 Schuler E, Lin F, Worman HJ. Characterization of the human gene encoding LBR, an integral protein of the nuclear envelope inner membrane Journal of Biological Chemistry. 269: 11312-11317. PMID 8157663  1
1994 Ye Q, Worman HJ. Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane. The Journal of Biological Chemistry. 269: 11306-11. PMID 8157662  1
1994 Worman HJ. Primary biliary cirrhosis and the molecular cell biology of the nuclear envelope Mount Sinai Journal of Medicine. 61: 461-475. PMID 7838161  1
1993 Theise ND, Miller F, Worman HJ, Morris P, Schwartz M, Miller C, Thung SN. Biliary cystadenocarcinoma arising in a liver with fibropolycystic disease Archives of Pathology and Laboratory Medicine. 117: 163-165. PMID 8427564  1
1993 Hytiroglou P, Wook Choi S, Theise ND, Chaudhary N, Worman HJ, Thung SN. The expression of nuclear lamins in human liver: An immunohistochemical study Human Pathology. 24: 169-172. PMID 8381765 DOI: 10.1016/0046-8177(93)90296-S  1
1993 Lin F, Worman HJ. Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C Journal of Biological Chemistry. 268: 16321-16326. PMID 8344919  1
1993 Soullam B, Worman HJ. The amino-terminal domain of the lamin B receptor is a nuclear envelope targeting signal Journal of Cell Biology. 120: 1093-1100. PMID 7679672  1
1993 Nickowitz RE, Worman HJ. Autoantibodies from patients with primary biliary cirrhosis recognize a restricted region within the cytoplasmic tail of nuclear pore membrane glycoprotein gp210 Journal of Experimental Medicine. 178: 2237-2242. PMID 7504063 DOI: 10.1084/jem.178.6.2237  1
1992 Dannenberg AJ, Worman HJ, Scarlata S. Developmental changes in the amount and functional state of UDP-glucuronosyltransferase Bba - General Subjects. 1116: 250-255. PMID 1610880 DOI: 10.1016/0304-4165(92)90036-T  1
1992 Worman HJ, Ip JH, Winters SL, Tepper DC, Gomes AJ. Hypersensitivity reaction associated with acute hepatic dysfunction following a single intravenous dose of procainamide Journal of Internal Medicine. 232: 361-363. PMID 1402640  1
1992 Courvalin JC, Segil N, Blobel G, Worman HJ. The lamin B receptor of the inner nuclear membrane undergoes mitosis-specific phosphorylation and is a substrate for p34cdc2-type protein kinase. The Journal of Biological Chemistry. 267: 19035-8. PMID 1326541  1
1992 Berk PD, Worman HJ. An introduction to molecular biology and recombinant DNA technology for the hepatologist Seminars in Liver Disease. 12: 227-245. PMID 1279814  1
1992 Cance WG, Chaudhary N, Worman HJ, Blobel G, Cordon-Cardo C. Expression of the nuclear lamins in normal and neoplastic human tissues Journal of Experimental and Clinical Cancer Research. 11: 233-246.  1
1991 Worman HJ, Courvalin JC. Autoantibodies against nuclear envelope proteins in liver disease Hepatology. 14: 1269-1279. PMID 1959878  1
1990 Worman HJ, Evans CD, Blobel G. The lamin B receptor of the nuclear envelope inner membrane: a polytopic protein with eight potential transmembrane domains. The Journal of Cell Biology. 111: 1535-42. PMID 2170422  1
1990 Courvalin JC, Lassoued K, Worman HJ, Blobel G. Identification and characterization of autoantibodies against the nuclear envelope lamin B receptor from patients with primary biliary cirrhosis. The Journal of Experimental Medicine. 172: 961-7. PMID 2167346  1
1990 Worman HJ. Cellular intermediate filament networks and their derangement in alcoholic hepatitis Alcoholism: Clinical and Experimental Research. 14: 789-804. PMID 2088113 DOI: 10.1111/j.1530-0277.1990.tb01816.x  1
1988 Worman HJ, Lazaridis I, Georgatos SD. Nuclear lamina heterogeneity in mammalian cells. Differential expression of the major lamins and variations in lamin B phosphorylation Journal of Biological Chemistry. 263: 12135-12141. PMID 3403563  1
1988 Worman HJ, Yuan J, Blobel G, Georgatos SD. A lamin B receptor in the nuclear envelope. Proceedings of the National Academy of Sciences of the United States of America. 85: 8531-4. PMID 2847165  1
1987 Worman HJ. Excessive use of urine cultures for inpatients Annals of Internal Medicine. 107: 115-116. PMID 3592429  1
1986 Worman HJ, Brasitus TA, Dudeja PK, Fozzard HA, Field M. Relationship between lipid fluidity and water permeability of bovine tracheal epithelial cell apical membranes Biochemistry. 25: 1549-1555. PMID 3707892  1
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