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David W. Andrews - Publications

McMaster University, Hamilton, ON, Canada 
 University of Toronto, Toronto, ON, Canada 

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pogmore JP, Pemberton JM, Chi X, Andrews DW. Using Förster-Resonance Energy Transfer to Measure Protein Interactions Between Bcl-2 Family Proteins on Mitochondrial Membranes. Methods in Molecular Biology (Clifton, N.J.). 1419: 197-212. PMID 27108441 DOI: 10.1007/978-1-4939-3581-9_15  1
2016 Brahmbhatt H, Uehling D, Al-Awar R, Leber B, Andrews D. Small molecules reveal an alternative mechanism of Bax activation. The Biochemical Journal. 473: 1073-83. PMID 26916338 DOI: 10.1042/Bcj20160118  1
2016 Thébault S, Agez M, Chi X, Stojko J, Cura V, Telerman SB, Maillet L, Gautier F, Billas-Massobrio I, Birck C, Troffer-Charlier N, Karafin T, Honoré J, Senff-Ribeiro A, Montessuit S, ... ... Andrews DW, et al. TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL. Scientific Reports. 6: 19725. PMID 26813996 DOI: 10.1038/Srep19725  1
2015 Zhang Z, Subramaniam S, Kale J, Liao C, Huang B, Brahmbhatt H, Condon SG, Lapolla SM, Hays FA, Ding J, He F, Zhang XC, Li J, Senes A, Andrews DW, et al. BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes. The Embo Journal. PMID 26702098 DOI: 10.15252/Embj.201591552  1
2015 Tsikouras A, Berman R, Andrews DW, Fang Q. High-speed multifocal array scanning using refractive window tilting. Biomedical Optics Express. 6: 3737-47. PMID 26504625 DOI: 10.1364/Boe.6.003737  1
2015 Collins TJ, Ylanko J, Geng F, Andrews DW. A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis. Assay and Drug Development Technologies. PMID 26422066 DOI: 10.1089/Adt.2015.661  1
2015 Goujon LJ, Hariharan S, Sayyar B, Burke NA, Cranston ED, Andrews DW, Stöver HD. Tunable hydrogel thin films from reactive synthetic polymers as potential two-dimensional cell scaffolds. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 5623-32. PMID 25907892 DOI: 10.1021/Acs.Langmuir.5B00376  1
2015 Brahmbhatt H, Oppermann S, Osterlund EJ, Leber B, Andrews DW. Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells-Mitochondrial Outer Membrane Permeabilization and Beyond. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2671-6. PMID 25838396 DOI: 10.1158/1078-0432.Ccr-14-0959  1
2015 Yeh SC, Sahli S, Andrews DW, Patterson MS, Armstrong D, Provias J, Fang Q. 5-aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models. Journal of Biomedical Optics. 20: 36010. PMID 25790343 DOI: 10.1117/1.Jbo.20.3.036010  1
2015 Shamas-Din A, Bindner S, Chi X, Leber B, Andrews DW, Fradin C. Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax. The Biochemical Journal. 467: 495-505. PMID 25714678 DOI: 10.1042/Bj20141291  1
2015 Yeh SC, Ling CS, Andrews DW, Patterson MS, Diamond KR, Hayward JE, Armstrong D, Fang Q. 5-aminolevulinic acid for quantitative seek-and-treat of high-grade dysplasia in Barrett's esophagus cellular models. Journal of Biomedical Optics. 20: 28002. PMID 25671673 DOI: 10.1117/1.Jbo.20.2.028002  1
2015 Osterlund EJ, Liu Q, Andrews DW. The use of FLIM-FRET for the detection of mitochondria-associated protein interactions. Methods in Molecular Biology (Clifton, N.J.). 1264: 395-419. PMID 25631031 DOI: 10.1007/978-1-4939-2257-4_34  1
2015 Mills CE, Thome C, Koff D, Andrews DW, Boreham DR. The relative biological effectiveness of low-dose mammography quality X rays in the human breast MCF-10A cell line. Radiation Research. 183: 42-51. PMID 25536231 DOI: 10.1667/Rr13821.1  1
2015 Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137  1
2014 Andrews DW. Pores of no return. Molecular Cell. 56: 465-6. PMID 25459877 DOI: 10.1016/J.Molcel.2014.11.005  1
2014 Marty NJ, Teresinski HJ, Hwang YT, Clendening EA, Gidda SK, Sliwinska E, Zhang D, Miernyk JA, Brito GC, Andrews DW, Dyer JM, Mullen RT. New insights into the targeting of a subset of tail-anchored proteins to the outer mitochondrial membrane. Frontiers in Plant Science. 5: 426. PMID 25237314 DOI: 10.3389/Fpls.2014.00426  1
2014 Kale J, Chi X, Leber B, Andrews D. Examining the molecular mechanism of bcl-2 family proteins at membranes by fluorescence spectroscopy. Methods in Enzymology. 544: 1-23. PMID 24974284 DOI: 10.1016/B978-0-12-417158-9.00001-7  1
2014 Chi X, Kale J, Leber B, Andrews DW. Regulating cell death at, on, and in membranes. Biochimica Et Biophysica Acta. 1843: 2100-13. PMID 24927885 DOI: 10.1016/J.Bbamcr.2014.06.002  1
2014 Shamas-Din A, Satsoura D, Khan O, Zhu W, Leber B, Fradin C, Andrews DW. Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid. Cell Death & Disease. 5: e1277. PMID 24901048 DOI: 10.1038/Cddis.2014.234  1
2014 Shivakumar S, Kurylowicz M, Hirmiz N, Manan Y, Friaa O, Shamas-Din A, Masoudian P, Leber B, Andrews DW, Fradin C. The proapoptotic protein tBid forms both superficially bound and membrane-inserted oligomers. Biophysical Journal. 106: 2085-95. PMID 24853737 DOI: 10.1016/J.Bpj.2014.03.049  1
2014 Ding J, Mooers BH, Zhang Z, Kale J, Falcone D, McNichol J, Huang B, Zhang XC, Xing C, Andrews DW, Lin J. After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization. The Journal of Biological Chemistry. 289: 11873-96. PMID 24616095 DOI: 10.1074/Jbc.M114.552562  1
2014 Borner C, Andrews DW. The apoptotic pore on mitochondria: are we breaking through or still stuck? Cell Death and Differentiation. 21: 187-91. PMID 24413197 DOI: 10.1038/Cdd.2013.169  1
2014 Liu Q, Chi X, Leber B, Andrews DW. Bcl-2 family and their therapeutic potential Cell Death: Mechanism and Disease. 2147483647: 61-96. DOI: 10.1007/978-1-4614-9302-0_4  1
2013 Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A. BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response. Molecular Cell. 51: 751-65. PMID 24074954 DOI: 10.1016/J.Molcel.2013.08.048  1
2013 Vanner SA, Li X, Zvanych R, Torchia J, Sang J, Andrews DW, Magarvey NA. Chemical and biosynthetic evolution of the antimycin-type depsipeptides. Molecular Biosystems. 9: 2712-9. PMID 23989727 DOI: 10.1039/C3Mb70219G  1
2013 Friaa O, Furukawa M, Shamas-Din A, Leber B, Andrews DW, Fradin C. Optimizing the acquisition and analysis of confocal images for quantitative single-mobile-particle detection. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 14: 2476-90. PMID 23824691 DOI: 10.1002/Cphc.201201047  1
2013 Shamas-Din A, Bindner S, Zhu W, Zaltsman Y, Campbell C, Gross A, Leber B, Andrews DW, Fradin C. tBid undergoes multiple conformational changes at the membrane required for Bax activation. The Journal of Biological Chemistry. 288: 22111-27. PMID 23744079 DOI: 10.1074/Jbc.M113.482109  1
2013 Shamas-Din A, Kale J, Leber B, Andrews DW. Mechanisms of action of Bcl-2 family proteins. Cold Spring Harbor Perspectives in Biology. 5: a008714. PMID 23545417 DOI: 10.1101/Cshperspect.A008714  1
2012 Kale J, Liu Q, Leber B, Andrews DW. Shedding light on apoptosis at subcellular membranes. Cell. 151: 1179-84. PMID 23217705 DOI: 10.1016/J.Cell.2012.11.013  1
2012 Liu Q, Leber B, Andrews DW. Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET. Cell Cycle (Georgetown, Tex.). 11: 3536-42. PMID 22895112 DOI: 10.4161/Cc.21462  1
2012 Tsikouras A, Ning J, Ng S, Berman R, Andrews DW, Fang Q. Streak camera crosstalk reduction using a multiple delay optical fiber bundle. Optics Letters. 37: 250-2. PMID 22854483 DOI: 10.1364/Ol.37.000250  1
2012 Geng F, Zhu W, Anderson RA, Leber B, Andrews DW. Multiple post-translational modifications regulate E-cadherin transport during apoptosis. Journal of Cell Science. 125: 2615-25. PMID 22375065 DOI: 10.1242/Jcs.096735  1
2012 Mergenthaler P, Kahl A, Kamitz A, van Laak V, Stohlmann K, Thomsen S, Klawitter H, Przesdzing I, Neeb L, Freyer D, Priller J, Collins TJ, Megow D, Dirnagl U, Andrews DW, et al. Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state. Proceedings of the National Academy of Sciences of the United States of America. 109: 1518-23. PMID 22233811 DOI: 10.1073/Pnas.1108225109  1
2012 Satsoura D, Kučerka N, Shivakumar S, Pencer J, Griffiths C, Leber B, Andrews DW, Katsaras J, Fradin C. Interaction of the full-length Bax protein with biomimetic mitochondrial liposomes: a small-angle neutron scattering and fluorescence study. Biochimica Et Biophysica Acta. 1818: 384-401. PMID 22037145 DOI: 10.1016/J.Bbamem.2011.10.007  1
2011 Brito GC, Andrews DW. Removing bias against membrane proteins in interaction networks. Bmc Systems Biology. 5: 169. PMID 22011625 DOI: 10.1186/1752-0509-5-169  1
2011 Craney A, Tahlan K, Andrews D, Nodwell J. Bacterial transmembrane proteins that lack N-terminal signal sequences. Plos One. 6: e19421. PMID 21573234 DOI: 10.1371/Journal.Pone.0019421  1
2011 Falcone D, Henderson MP, Nieuwland H, Coughlan CM, Brodsky JL, Andrews DW. Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence. The Biochemical Journal. 436: 291-303. PMID 21355855 DOI: 10.1042/Bj20101865  1
2011 Gidda SK, Shockey JM, Falcone M, Kim PK, Rothstein SJ, Andrews DW, Dyer JM, Mullen RT. Hydrophobic-domain-dependent protein-protein interactions mediate the localization of GPAT enzymes to ER subdomains. Traffic (Copenhagen, Denmark). 12: 452-72. PMID 21214700 DOI: 10.1111/J.1600-0854.2011.01160.X  1
2011 Shamas-Din A, Brahmbhatt H, Leber B, Andrews DW. BH3-only proteins: Orchestrators of apoptosis. Biochimica Et Biophysica Acta. 1813: 508-20. PMID 21146563 DOI: 10.1016/J.Bbamcr.2010.11.024  1
2010 Leber B, Andrews DW. Closing in on the link between apoptosis and autophagy. F1000 Biology Reports. 2: 88. PMID 21283600 DOI: 10.3410/B2-88  1
2010 Leber B, Geng F, Kale J, Andrews DW. Drugs targeting Bcl-2 family members as an emerging strategy in cancer. Expert Reviews in Molecular Medicine. 12: e28. PMID 20822554 DOI: 10.1017/S1462399410001572  1
2010 Bogner C, Leber B, Andrews DW. Apoptosis: embedded in membranes. Current Opinion in Cell Biology. 22: 845-51. PMID 20801011 DOI: 10.1016/J.Ceb.2010.08.002  1
2010 Leber B, Lin J, Andrews DW. Still embedded together binding to membranes regulates Bcl-2 protein interactions. Oncogene. 29: 5221-30. PMID 20639903 DOI: 10.1038/Onc.2010.283  1
2010 Ding J, Zhang Z, Roberts GJ, Falcone M, Miao Y, Shao Y, Zhang XC, Andrews DW, Lin J. Bcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motif. The Journal of Biological Chemistry. 285: 28749-63. PMID 20584903 DOI: 10.1074/Jbc.M110.148361  1
2010 Mian MF, Lauzon NM, Andrews DW, Lichty BD, Ashkar AA. FimH can directly activate human and murine natural killer cells via TLR4. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1379-88. PMID 20442710 DOI: 10.1038/Mt.2010.75  1
2010 Dhanoa PK, Richardson LG, Smith MD, Gidda SK, Henderson MP, Andrews DW, Mullen RT. Distinct pathways mediate the sorting of tail-anchored proteins to the plastid outer envelope. Plos One. 5: e10098. PMID 20418952 DOI: 10.1371/Journal.Pone.0010098  1
2010 Zhang Z, Zhu W, Lapolla SM, Miao Y, Shao Y, Falcone M, Boreham D, McFarlane N, Ding J, Johnson AE, Zhang XC, Andrews DW, Lin J. Bax forms an oligomer via separate, yet interdependent, surfaces. The Journal of Biological Chemistry. 285: 17614-27. PMID 20382739 DOI: 10.1074/Jbc.M110.113456  1
2009 Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death and Differentiation. 16: 1093-107. PMID 19373242 DOI: 10.1038/Cdd.2009.44  1
2009 Lam L, Hu X, Aktary Z, Andrews DW, Pasdar M. Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit growth of breast carcinoma cells by modulating PI3K/AKT, ERK and IGF-1R pathways independent of ERalpha. Breast Cancer Research and Treatment. 118: 605-21. PMID 19002577 DOI: 10.1007/S10549-008-0231-Y  1
2008 Billen LP, Shamas-Din A, Andrews DW. Bid: a Bax-like BH3 protein. Oncogene. 27: S93-104. PMID 19641510 DOI: 10.1038/Onc.2009.47  1
2008 Lovell JF, Billen LP, Bindner S, Shamas-Din A, Fradin C, Leber B, Andrews DW. Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax. Cell. 135: 1074-84. PMID 19062087 DOI: 10.1016/J.Cell.2008.11.010  1
2008 Billen LP, Kokoski CL, Lovell JF, Leber B, Andrews DW. Bcl-XL inhibits membrane permeabilization by competing with Bax. Plos Biology. 6: e147. PMID 18547146 DOI: 10.1371/Journal.Pbio.0060147  1
2008 Wang L, Kong F, Kokoski CL, Andrews DW, Xing C. Development of dimeric modulators for anti-apoptotic Bcl-2 proteins. Bioorganic & Medicinal Chemistry Letters. 18: 236-40. PMID 18023349 DOI: 10.1016/J.Bmcl.2007.10.088  1
2007 Keita M, Leblanc C, Andrews D, Ramanathan S. GIMAP5 regulates mitochondrial integrity from a distinct subcellular compartment. Biochemical and Biophysical Research Communications. 361: 481-6. PMID 17655828 DOI: 10.1016/J.Bbrc.2007.07.048  1
2007 Leber B, Lin J, Andrews DW. Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes. Apoptosis : An International Journal On Programmed Cell Death. 12: 897-911. PMID 17453159 DOI: 10.1007/S10495-007-0746-4  1
2007 Satsoura D, Leber B, Andrews DW, Fradin C. Circumvention of fluorophore photobleaching in fluorescence fluctuation experiments: a beam scanning approach. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 8: 834-48. PMID 17394281 DOI: 10.1002/Cphc.200600589  1
2007 Henderson MP, Billen LP, Kim PK, Andrews DW. Cell-free analysis of tail-anchor protein targeting to membranes. Methods (San Diego, Calif.). 41: 427-38. PMID 17367715 DOI: 10.1016/J.Ymeth.2006.07.004  1
2007 Criollo A, Maiuri MC, Tasdemir E, Vitale I, Fiebig AA, Andrews D, Molgó J, Díaz J, Lavandero S, Harper F, Pierron G, di Stefano D, Rizzuto R, Szabadkai G, Kroemer G. Regulation of autophagy by the inositol trisphosphate receptor Cell Death and Differentiation. 14: 1029-1039. PMID 17256008 DOI: 10.1038/Sj.Cdd.4402099  1
2007 Henderson MP, Hwang YT, Dyer JM, Mullen RT, Andrews DW. The C-terminus of cytochrome b5 confers endoplasmic reticulum specificity by preventing spontaneous insertion into membranes. The Biochemical Journal. 401: 701-9. PMID 16984229 DOI: 10.1042/Bj20060990  1
2007 Xu L, Kong D, Zhu L, Zhu W, Andrews DW, Kuo TH. Suppression of IP3-mediated calcium release and apoptosis by Bcl-2 involves the participation of protein phosphatase 1. Molecular and Cellular Biochemistry. 295: 153-65. PMID 16874461 DOI: 10.1007/S11010-006-9285-5  1
2007 Mainprize IL, Vulcu F, Andrews DW. The Signal Recognition Particle and Its Receptor in ER Protein Targeting Enzymes. 25: 175,177-206. DOI: 10.1016/S1874-6047(07)25008-5  1
2006 Peng J, Tan C, Roberts GJ, Nikolaeva O, Zhang Z, Lapolla SM, Primorac S, Andrews DW, Lin J. tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation. The Journal of Biological Chemistry. 281: 35802-11. PMID 17005564 DOI: 10.1074/Jbc.M608303200  1
2006 Mainprize IL, Beniac DR, Falkovskaia E, Cleverley RM, Gierasch LM, Ottensmeyer FP, Andrews DW. The structure of Escherichia coli signal recognition particle revealed by scanning transmission electron microscopy. Molecular Biology of the Cell. 17: 5063-74. PMID 16987964 DOI: 10.1091/Mbc.E06-05-0384  1
2006 Fiebig AA, Zhu W, Hollerbach C, Leber B, Andrews DW. Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line. Bmc Cancer. 6: 213. PMID 16928273 DOI: 10.1186/1471-2407-6-213  1
2006 Dlugosz PJ, Billen LP, Annis MG, Zhu W, Zhang Z, Lin J, Leber B, Andrews DW. Bcl-2 changes conformation to inhibit Bax oligomerization. The Embo Journal. 25: 2287-96. PMID 16642033 DOI: 10.1038/Sj.Emboj.7601126  1
2006 Tan C, Dlugosz PJ, Peng J, Zhang Z, Lapolla SM, Plafker SM, Andrews DW, Lin J. Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2. The Journal of Biological Chemistry. 281: 14764-75. PMID 16571718 DOI: 10.1074/Jbc.M602374200  1
2005 Kong D, Xu L, Yu Y, Zhu W, Andrews DW, Yoon Y, Kuo TH. Regulation of Ca2+-induced permeability transition by Bcl-2 is antagonized by Drpl and hFis1. Molecular and Cellular Biochemistry. 272: 187-99. PMID 16010987 DOI: 10.1007/S11010-005-7323-3  1
2005 Tyers M, Brown E, Andrews DW, Bergeron JJ, Boone C, Bremner R, Bussey HA, Cross JC, Davies JE, Desjardins M, Dick JE, Dumont DJ, Durocher D, Ellison MJ, Golding GB, et al. Problems with co-funding in Canada. Science (New York, N.Y.). 308: 1867. PMID 15976286 DOI: 10.1126/Science.308.5730.1867B  1
2005 Annis MG, Soucie EL, Dlugosz PJ, Cruz-Aguado JA, Penn LZ, Leber B, Andrews DW. Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis. The Embo Journal. 24: 2096-103. PMID 15920484 DOI: 10.1038/Sj.Emboj.7600675  1
2004 Hwang YT, Pelitire SM, Henderson MP, Andrews DW, Dyer JM, Mullen RT. Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria. The Plant Cell. 16: 3002-19. PMID 15486098 DOI: 10.1105/Tpc.104.026039  1
2004 Zhang Z, Lapolla SM, Annis MG, Truscott M, Roberts GJ, Miao Y, Shao Y, Tan C, Peng J, Johnson AE, Zhang XC, Andrews DW, Lin J. Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax. The Journal of Biological Chemistry. 279: 43920-8. PMID 15302859 DOI: 10.1074/Jbc.M406412200  1
2004 Kim PK, Annis MG, Dlugosz PJ, Leber B, Andrews DW. During apoptosis bcl-2 changes membrane topology at both the endoplasmic reticulum and mitochondria. Molecular Cell. 14: 523-9. PMID 15149601 DOI: 10.1016/S1097-2765(04)00263-1  1
2004 Annis MG, Yethon JA, Leber B, Andrews DW. There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum. Biochimica Et Biophysica Acta. 1644: 115-23. PMID 14996496 DOI: 10.1016/J.Bbamcr.2003.07.001  1
2004 McCartney AW, Dyer JM, Dhanoa PK, Kim PK, Andrews DW, McNew JA, Mullen RT. Membrane-bound fatty acid desaturases are inserted co-translationally into the ER and contain different ER retrieval motifs at their carboxy termini. The Plant Journal : For Cell and Molecular Biology. 37: 156-73. PMID 14690501 DOI: 10.1111/J.1365-313X.2004.01949.X  1
2003 Xue LY, Chiu SM, Fiebig A, Andrews DW, Oleinick NL. Photodamage to multiple Bcl-xL isoforms by photodynamic therapy with the phthalocyanine photosensitizer Pc 4. Oncogene. 22: 9197-204. PMID 14681679 DOI: 10.1038/Sj.Onc.1207019  1
2003 Yethon JA, Epand RF, Leber B, Epand RM, Andrews DW. Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis. The Journal of Biological Chemistry. 278: 48935-41. PMID 14522999 DOI: 10.1074/Jbc.M306289200  1
2003 Legate KR, Andrews DW. The beta-subunit of the signal recognition particle receptor is a novel GTP-binding protein without intrinsic GTPase activity. The Journal of Biological Chemistry. 278: 27712-20. PMID 12759365 DOI: 10.1074/Jbc.M302158200  1
2003 Janumyan YM, Sansam CG, Chattopadhyay A, Cheng N, Soucie EL, Penn LZ, Andrews D, Knudson CM, Yang E. Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry Embo Journal. 22: 5459-5470. DOI: 10.1093/emboj/cdg533  1
2002 Andrews DW. Protein origami for beginners. Developmental Cell. 3: 608-10. PMID 12431366 DOI: 10.1016/S1534-5807(02)00333-7  1
2001 Legate KR, Andrews DW. Assembly strategies and GTPase regulation of the eukaryotic and Escherichia coil translocons. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 79: 593-601. PMID 11716301 DOI: 10.1139/O01-140  1
2001 Zhu W, Leber B, Andrews DW. Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosis. The Embo Journal. 20: 5999-6007. PMID 11689440 DOI: 10.1093/Emboj/20.21.5999  1
2001 Soucie EL, Annis MG, Sedivy J, Filmus J, Leber B, Andrews DW, Penn LZ. Myc potentiates apoptosis by stimulating Bax activity at the mitochondria. Molecular and Cellular Biology. 21: 4725-36. PMID 11416148 DOI: 10.1128/Mcb.21.14.4725-4736.2001  1
2001 Annis MG, Zamzami N, Zhu W, Penn LZ, Kroemer G, Leber B, Andrews DW. Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event. Oncogene. 20: 1939-52. PMID 11360178 DOI: 10.1038/Sj.Onc.1204288  1
2001 Millman JS, Qi HY, Vulcu F, Bernstein HD, Andrews DW. FtsY binds to the Escherichia coli inner membrane via interactions with phosphatidylethanolamine and membrane proteins. The Journal of Biological Chemistry. 276: 25982-9. PMID 11353766 DOI: 10.1074/Jbc.M011331200  1
2001 Soltys BJ, Andrews DW, Jemmerson R, Gupta RS. Cytochrome-C localizes in secretory granules in pancreas and anterior pituitary. Cell Biology International. 25: 331-8. PMID 11319839 DOI: 10.1006/Cbir.2000.0651  1
2000 Andrews DW. Transport across membranes: a question of navigation. Cell. 102: 139-44. PMID 10943834 DOI: 10.1016/S0092-8674(00)00019-2  1
2000 Legate KR, Falcone D, Andrews DW. Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor beta-subunit to the alpha-subunit. The Journal of Biological Chemistry. 275: 27439-46. PMID 10859309 DOI: 10.1074/Jbc.M003215200  1
2000 Daugas E, Susin SA, Zamzami N, Ferri KF, Irinopoulou T, Larochette N, Prévost MC, Leber B, Andrews D, Penninger J, Kroemer G. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis Faseb Journal. 14: 729-739. PMID 10744629 DOI: 10.1096/Fasebj.14.5.729  1
2000 Brenner C, Cadiou H, Vieira HLA, Zamzami N, Marzo I, Xie Z, Leber B, Andrews D, Duclohier H, Reed JC, Kroemer G. Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator Oncogene. 19: 329-336. PMID 10656679 DOI: 10.1038/Sj.Onc.1203298  1
1999 Kim PK, Hollerbach C, Trimble WS, Leber B, Andrews DW. Identification of the endoplasmic reticulum targeting signal in vesicle-associated membrane proteins. The Journal of Biological Chemistry. 274: 36876-82. PMID 10601239 DOI: 10.1074/Jbc.274.52.36876  1
1999 Falcone D, Do H, Johnson AE, Andrews DW. Negatively charged residues in the IgM stop-transfer effector sequence regulate transmembrane polypeptide integration. The Journal of Biological Chemistry. 274: 33661-70. PMID 10559255 DOI: 10.1074/Jbc.274.47.33661  1
1999 Millman JS, Andrews DW. A site-specific, membrane-dependent cleavage event defines the membrane binding domain of FtsY. The Journal of Biological Chemistry. 274: 33227-34. PMID 10559196 DOI: 10.1074/Jbc.274.47.33227  1
1999 Thangaraju M, Sharma K, Leber B, Andrews DW, Shen SH, Srikant CB. Regulation of acidification and apoptosis by SHP-1 and Bcl-2. The Journal of Biological Chemistry. 274: 29549-57. PMID 10506221 DOI: 10.1074/Jbc.274.41.29549  1
1999 Lee ST, Hoeflich KP, Wasfy GW, Woodgett JR, Leber B, Andrews DW, Hedley DW, Penn LZ. Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts. Oncogene. 18: 3520-8. PMID 10376530 DOI: 10.1038/Sj.Onc.1202716  1
1999 Froesch BA, Aimé-Sempé C, Leber B, Andrews D, Reed JC. Inhibition of p53 transcriptional activity by Bcl-2 requires its membrane-anchoring domain Journal of Biological Chemistry. 274: 6469-6475. PMID 10037739 DOI: 10.1074/Jbc.274.10.6469  1
1998 Zhu W, Eicher A, Leber B, Andrews DW. At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes. Oncogene. 17: 565-76. PMID 9704922 DOI: 10.1038/Sj.Onc.1201979  1
1998 Thomsen L, Robinson TL, Lee JC, Farraway LA, Hughes MJ, Andrews DW, Huizinga JD. Interstitial cells of Cajal generate a rhythmic pacemaker current. Nature Medicine. 4: 848-51. PMID 9662380 DOI: 10.1038/Nm0798-848  1
1997 Hughes MJ, Andrews DW. A single nucleotide is a sufficient 5' untranslated region for translation in an eukaryotic in vitro system. Febs Letters. 414: 19-22. PMID 9305724 DOI: 10.1016/S0014-5793(97)00965-4  1
1997 Kim PK, Janiak-Spens F, Trimble WS, Leber B, Andrews DW. Evidence for multiple mechanisms for membrane binding and integration via carboxyl-terminal insertion sequences. Biochemistry. 36: 8873-82. PMID 9220974 DOI: 10.1021/Bi970090T  1
1997 Millman JS, Andrews DW. Switching the model: a concerted mechanism for GTPases in protein targeting. Cell. 89: 673-6. PMID 9182753 DOI: 10.1016/S0092-8674(00)80248-2  1
1996 Andrews DW, Johnson AE. The translocon: more than a hole in the ER membrane? Trends in Biochemical Sciences. 21: 365-9. PMID 8918188 DOI: 10.1016/S0968-0004(96)10047-5  1
1996 Zhu W, Cowie A, Wasfy GW, Penn LZ, Leber B, Andrews DW. Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. The Embo Journal. 15: 4130-41. PMID 8861942 DOI: 10.1002/J.1460-2075.1996.Tb00788.X  1
1996 Do H, Falcone D, Lin J, Andrews DW, Johnson AE. The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process. Cell. 85: 369-78. PMID 8616892 DOI: 10.1016/S0092-8674(00)81115-0  0.68
1996 Young JC, Andrews DW. The signal recognition particle receptor alpha subunit assembles co-translationally on the endoplasmic reticulum membrane during an mRNA-encoded translation pause in vitro. The Embo Journal. 15: 172-81. PMID 8598200 DOI: 10.1002/J.1460-2075.1996.Tb00345.X  1
1995 Johnson AE, Liao S, Lin J, Hamman B, Do H, Cowie A, Andrews DW. The environment of nascent secretory and membrane proteins at the endoplasmic reticulum membrane during translocation and integration. Cold Spring Harbor Symposia On Quantitative Biology. 60: 71-82. PMID 8824379 DOI: 10.1101/Sqb.1995.060.01.010  0.4
1995 Young JC, Ursini J, Legate KR, Miller JD, Walter P, Andrews DW. An amino-terminal domain containing hydrophobic and hydrophilic sequences binds the signal recognition particle receptor alpha subunit to the beta subunit on the endoplasmic reticulum membrane. The Journal of Biological Chemistry. 270: 15650-7. PMID 7797564 DOI: 10.1074/Jbc.270.26.15650  1
1994 Janiak F, Glover JR, Leber B, Rachubinski RA, Andrews DW. Targeting of passenger protein domains to multiple intracellular membranes. The Biochemical Journal. 300: 191-9. PMID 8198533 DOI: 10.1042/Bj3000191  1
1994 Glover JR, Andrews DW, Subramani S, Rachubinski RA. Mutagenesis of the amino targeting signal of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for import into peroxisomes in vivo. The Journal of Biological Chemistry. 269: 7558-63. PMID 8125978  1
1994 Glover JR, Andrews DW, Rachubinski RA. Saccharomyces cerevisiae peroxisomal thiolase is imported as a dimer. Proceedings of the National Academy of Sciences of the United States of America. 91: 10541-5. PMID 7937990 DOI: 10.1073/Pnas.91.22.10541  1
1994 Czarnota GJ, Andrews DW, Farrow NA, Ottensmeyer FP. A structure for the signal sequence binding protein SRP54: 3D reconstruction from STEM images of single molecules. Journal of Structural Biology. 113: 35-46. PMID 7880651 DOI: 10.1006/Jsbi.1994.1030  1
1992 Andrews DW, Young JC, Mirels LF, Czarnota GJ. The role of the N region in signal sequence and signal-anchor function. The Journal of Biological Chemistry. 267: 7761-9. PMID 1560010  1
1991 Falcone D, Andrews DW. Both the 5' untranslated region and the sequences surrounding the start site contribute to efficient initiation of translation in vitro. Molecular and Cellular Biology. 11: 2656-64. PMID 2017171 DOI: 10.1128/Mcb.11.5.2656  0.68
1991 Thrift RN, Andrews DW, Walter P, Johnson AE. A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation. The Journal of Cell Biology. 112: 809-21. PMID 1999459 DOI: 10.1083/Jcb.112.5.809  0.6
1989 Andrews DW, Lauffer L, Walter P, Lingappa VR. Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor. The Journal of Cell Biology. 108: 797-810. PMID 2537835 DOI: 10.1083/Jcb.108.3.797  1
1988 Andrews DW, Perara E, Lesser C, Lingappa VR. Sequences beyond the cleavage site influence signal peptide function. The Journal of Biological Chemistry. 263: 15791-8. PMID 3170612  1
1988 Rothman RE, Andrews DW, Calayag MC, Lingappa VR. Construction of defined polytopic integral transmembrane proteins. The role of signal and stop transfer sequence permutations. The Journal of Biological Chemistry. 263: 10470-80. PMID 2839492  1
1988 Ottensmeyer FP, Andrews DW, Arsenault AL, Heng YM, Simon GT, Weatherly GC. Elemental imaging by electron energy loss microscopy Scanning. 10: 227-238. DOI: 10.1002/Sca.4950100604  1
1987 Andrews DW, Walter P, Ottensmeyer FP. Evidence for an extended 7SL RNA structure in the signal recognition particle. The Embo Journal. 6: 3471-7. PMID 2828031 DOI: 10.1002/J.1460-2075.1987.Tb02671.X  1
1986 Andrews DW, Yu AH, Ottensmeyer FP. Automatic selection of molecular images from dark field electron micrographs. Ultramicroscopy. 19: 1-14. PMID 3716002 DOI: 10.1016/0304-3991(86)90002-1  1
1986 Mize NK, Andrews DW, Lingappa VR. A stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane. Cell. 47: 711-9. PMID 3096576 DOI: 10.1016/0092-8674(86)90514-3  1
1985 Andrews DW, Walter P, Ottensmeyer FP. Structure of the signal recognition particle by electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 82: 785-9. PMID 3856232 DOI: 10.1073/Pnas.82.3.785  1
1983 Harauz G, Andrews DW, Ottensmeyer FP. Electron microscopic visualization of the sidechains of the poly-L-lysine alpha helix. Ultramicroscopy. 12: 59-64. PMID 6659150 DOI: 10.1016/0304-3991(83)90305-4  1
1982 Andrews DW, Ottensmeyer FP. Electron microscopy of the poly-L-lysine alpha-helix. Ultramicroscopy. 9: 337-48. PMID 7179570 DOI: 10.1016/0304-3991(82)90094-8  1
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