| Year |
Citation |
Score |
| 2020 |
Sierra S, Lippold KM, Stevens DL, Poklis JL, Dewey WL, González-Maeso J. Adjunctive effect of the serotonin 5-HT receptor agonist lorcaserin on opioid-induced antinociception in mice. Neuropharmacology. 107949. PMID 31987863 DOI: 10.1016/j.neuropharm.2020.107949 |
0.416 |
|
| 2019 |
Mischel RA, Muchhala KH, Dewey WL, Akbarali HI. The "culture" of pain control: A review of opioid-induced dysbiosis (OID) in antinociceptive tolerance. The Journal of Pain : Official Journal of the American Pain Society. PMID 31841668 DOI: 10.1016/J.Jpain.2019.11.015 |
0.347 |
|
| 2019 |
Ma H, Obeng S, Wang H, Zheng Y, Li M, Jali AM, Stevens D, Dewey WL, Selley DE, Zhang Y. Application of Bivalent Bioisostere Concept on Design and Discovery of Potent Opioid Receptor Modulators. Journal of Medicinal Chemistry. PMID 31782922 DOI: 10.1021/Acs.Jmedchem.9B01767 |
0.403 |
|
| 2019 |
Hill R, Roberts J, Maclachlan J, Dewey W, Kelly E, Henderson G. Prolonged ethanol administration prevents the development of tolerance to morphine-induced respiratory depression. Drug and Alcohol Dependence. 205: 107674. PMID 31715438 DOI: 10.1016/j.drugalcdep.2019.107674 |
0.313 |
|
| 2019 |
Hill R, Santhakumar R, Dewey W, Kelly E, Henderson G. Fentanyl depression of respiration: comparison with heroin and morphine. British Journal of Pharmacology. PMID 31499594 DOI: 10.1111/Bph.14860 |
0.322 |
|
| 2019 |
Komla E, Stevens DL, Zheng Y, Zhang Y, Dewey WL, Akbarali HI. Experimental colitis enhances the rate of antinociceptive tolerance to morphine via peripheral opioid receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 31248978 DOI: 10.1124/Jpet.119.256941 |
0.415 |
|
| 2019 |
Akbarali HI, Dewey WL. Gastrointestinal motility, dysbiosis and opioid-induced tolerance: is there a link? Nature Reviews. Gastroenterology & Hepatology. PMID 31024090 DOI: 10.1038/S41575-019-0150-X |
0.359 |
|
| 2019 |
Obeng S, Jali A, Zheng Y, Wang H, Schwienteck K, Chen C, Stevens DL, Akbarali H, Dewey WL, Banks ML, Liu-Chen LY, Selley DE, Zhang Y. Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment. Acs Chemical Neuroscience. PMID 30758946 DOI: 10.1021/Acschemneuro.9B00038 |
0.391 |
|
| 2019 |
Zheng Y, Obeng S, Wang H, Jali AM, Peddibhotla B, Williams D, Zou C, Stevens DL, Dewey WL, Akbarali HI, Selley DE, Zhang Y. Design, Synthesis, and Biological Evaluation of the Third Generation 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'- pyridyl)carboxamido]morphinan (NAP) Derivatives as Mu/Kappa Opioid Receptor Dual Selective Ligands. Journal of Medicinal Chemistry. PMID 30608693 DOI: 10.1021/Acs.Jmedchem.8B01158 |
0.391 |
|
| 2018 |
Obeng S, Wang H, Jali A, Stevens DL, Akbarali HI, Dewey WL, Selley DE, Zhang Y. Structure activity relationship studies of 6α- and 6β-indolylacetamidonaltrexamine derivatives as bitopic mu opioid receptor modulators and elaboration of the 'message-address concept' to comprehend their functional conversion. Acs Chemical Neuroscience. PMID 30156823 DOI: 10.1021/Acschemneuro.8B00349 |
0.335 |
|
| 2018 |
Zheng Y, Obeng S, Wang H, Stevens DL, Komla E, Selley DE, Dewey WL, Akbarali HI, Zhang Y. Methylation Products of 6β-N-heterocyclic substituted naltrexamine derivatives as potential peripheral opioid receptor modulators. Acs Chemical Neuroscience. PMID 30001114 DOI: 10.1021/Acschemneuro.8B00234 |
0.382 |
|
| 2018 |
Mischel RA, Dewey WL, Akbarali HI. Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators. Iscience. 2: 193-209. PMID 29888757 DOI: 10.1016/J.Isci.2018.03.003 |
0.356 |
|
| 2018 |
Hill R, Disney A, Conibear A, Sutcliffe K, Dewey W, Husbands S, Bailey C, Kelly E, Henderson G. The novel μ-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception. British Journal of Pharmacology. PMID 29582414 DOI: 10.1111/bph.14224 |
0.342 |
|
| 2018 |
Hill R, Dewey WL, Kelly E, Henderson G. Oxycodone-induced Tolerance to Respiratory Depression: Reversal by Ethanol, Pregabalin, and Protein Kinase C Inhibition. British Journal of Pharmacology. PMID 29574756 DOI: 10.1111/bph.14219 |
0.352 |
|
| 2018 |
Jacob JC, Sakakibara K, Mischel RA, Henderson G, Dewey WL, Akbarali HI. Ethanol Reversal of Oxycodone Tolerance in Dorsal Root Ganglia Neurons. Molecular Pharmacology. PMID 29467238 DOI: 10.1124/Mol.117.110775 |
0.317 |
|
| 2018 |
Jacob JC, David B, Khan A, Dewey WL, Akbarali HI. Mo1578 - The Effect of a G-Protein Biased Ligand, TRV130, on Opioid-Induced Constipation Gastroenterology. 154: S-758. DOI: 10.1016/S0016-5085(18)32629-5 |
0.312 |
|
| 2017 |
Gonek M, McLane VD, Stevens DL, Lippold K, Akbarali HI, Knapp PE, Dewey WL, Hauser KF, Paris JJ. CCR5 mediates HIV-1 Tat-induced neuroinflammation and influences morphine tolerance, dependence, and reward. Brain, Behavior, and Immunity. PMID 29146238 DOI: 10.1016/J.Bbi.2017.11.006 |
0.401 |
|
| 2017 |
Akbarali HI, Dewey WL. The gut-brain interaction in opioid tolerance. Current Opinion in Pharmacology. 37: 126-130. PMID 29145012 DOI: 10.1016/J.Coph.2017.10.012 |
0.355 |
|
| 2017 |
Gonek M, Akbarali HI, Henderson G, Dewey WL. Reversal of Oxycodone and Hydrocodone Tolerance by Diazepam. Brain Research. PMID 28830768 DOI: 10.1016/J.Brainres.2017.08.017 |
0.389 |
|
| 2017 |
Jacob JC, Poklis JL, Akbarali HI, Henderson G, Dewey WL. Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone. The Journal of Pharmacology and Experimental Therapeutics. PMID 28442580 DOI: 10.1124/Jpet.117.241083 |
0.344 |
|
| 2017 |
Bhave S, Gade A, Kang M, Hauser KF, Dewey WL, Akbarali HI. Connexin-purinergic signaling in enteric glia mediates the prolonged effect of morphine on constipation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28280004 DOI: 10.1096/Fj.201601068R |
0.38 |
|
| 2017 |
Kang M, Mischel RA, Bhave S, Komla E, Cho A, Huang C, Dewey WL, Akbarali HI. The effect of gut microbiome on tolerance to morphine mediated antinociception in mice. Scientific Reports. 7: 42658. PMID 28211545 DOI: 10.1038/Srep42658 |
0.403 |
|
| 2017 |
Withey SL, Hill R, Lyndon A, Dewey WL, Kelly E, Henderson G. Effect of tamoxifen and brain penetrant PKC and JNK inhibitors on tolerance to opioid-induced respiratory depression in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 28130265 DOI: 10.1124/Jpet.116.238329 |
0.4 |
|
| 2017 |
Xu GG, Zolotarskaya OY, Williams DA, Yuan Y, Selley DE, Dewey WL, Akbarali HI, Yang H, Zhang Y. Nanoconjugated NAP as a Potent and Periphery Selective Mu Opioid Receptor Modulator To Treat Opioid-Induced Constipation. Acs Medicinal Chemistry Letters. 8: 78-83. PMID 28105279 DOI: 10.1021/Acsmedchemlett.6B00382 |
0.369 |
|
| 2017 |
Mischel R, Dewey WL, Akbarali HI. Colonic Supernatants from Chronic Morphine Exposed Mice Induce Morphine Tolerance in Naïve Dorsal Root Ganglion Neurons that is Mitigated by Oral Vancomycin Delivery Gastroenterology. 152: S730. DOI: 10.1016/S0016-5085(17)32537-4 |
0.378 |
|
| 2017 |
Muchhala K, Gade A, Dewey WL, Akbarali HI. μ-Opioid Receptors Co-Expressed in Cholinergic Neurons of Mouse Ileum Myenteric Plexus Develop Tolerance to Chronic Morphine Exposure Gastroenterology. 152: S710. DOI: 10.1016/S0016-5085(17)32478-2 |
0.354 |
|
| 2017 |
Lippold K, Dewey W. The Role of 5-HT2a/2c Receptors in Nociception and Opioid Antinociception: a Review of the Preclinical Literature Current Treatment Options in Psychiatry. 4: 210-220. DOI: 10.1007/s40501-017-0111-3 |
0.362 |
|
| 2016 |
Williams DA, Zheng Y, David BG, Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Selley DE, Dewey WL, Akbarali HI, Zhang Y. 6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand. Acs Chemical Neuroscience. PMID 27269866 DOI: 10.1021/Acschemneuro.6B00075 |
0.384 |
|
| 2016 |
Gade AR, Kang M, Khan F, Grider JR, Damaj MI, Dewey WL, Akbarali HI. Enhanced sensitivity of α3β4 nicotinic receptors in enteric neurons after chronic morphine: implication for opioid-induced constipation. The Journal of Pharmacology and Experimental Therapeutics. PMID 27068812 DOI: 10.1124/Jpet.116.233304 |
0.34 |
|
| 2016 |
Wilkerson JL, Niphakis MJ, Grim TW, Mustafa MA, Abdullah RA, Poklis JL, Dewey WL, Akbarali HI, Banks ML, Wise LE, Cravatt BF, Lichtman AH. The selective monoacylglycerol lipase inhibitor MJN110 produces opioid sparing effects in a mouse neuropathic pain model. The Journal of Pharmacology and Experimental Therapeutics. PMID 26791602 DOI: 10.1124/Jpet.115.229971 |
0.547 |
|
| 2016 |
Akbarali HI, Kang M, Mischel R, Bhave S, Gade A, Sakakibara K, Komla E, Muchhala K, Dewey W. Su1940 The Role of the Gastrointestinal Microbiota in Opioid-Induced Analgesic Tolerance Gastroenterology. 150: S594-S595. DOI: 10.1016/S0016-5085(16)32039-X |
0.355 |
|
| 2015 |
Zhang Y, Williams DA, Zaidi SA, Yuan Y, Braithwaite A, Bilsky EJ, Dewey WL, Akbarali HI, Streicher JM, Selley DE. 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) modulating the mu opioid receptor in a biased fashion. Acs Chemical Neuroscience. PMID 26716358 DOI: 10.1021/Acschemneuro.5B00245 |
0.327 |
|
| 2015 |
Fitting S, Stevens DL, Khan FA, Scoggins KL, Enga RM, Beardsley PM, Knapp PE, Dewey WL, Hauser KF. Morphine tolerance and physical dependence are altered in conditional HIV-1 Tat transgenic mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 26542403 DOI: 10.1124/Jpet.115.226407 |
0.36 |
|
| 2015 |
Yuan Y, Zaidi SA, Stevens DL, Scoggins KL, Mosier PD, Kellogg GE, Dewey WL, Selley DE, Zhang Y. Design, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligands. Bioorganic & Medicinal Chemistry. 23: 1701-15. PMID 25783191 DOI: 10.1016/J.Bmc.2015.02.055 |
0.366 |
|
| 2014 |
Akbarali HI, Inkisar A, Dewey WL. Site and mechanism of morphine tolerance in the gastrointestinal tract. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 26: 1361-7. PMID 25257923 DOI: 10.1111/Nmo.12443 |
0.381 |
|
| 2014 |
Smith TH, Ngwainmbi J, Hashimoto A, Dewey WL, Akbarali HI. Morphine dependence in single enteric neurons from the mouse colon requires deletion of β-arrestin2. Physiological Reports. 2. PMID 25194025 DOI: 10.14814/Phy2.12140 |
0.35 |
|
| 2013 |
Yuan Y, Zaidi SA, Elbegdorj O, Aschenbach LC, Li G, Stevens DL, Scoggins KL, Dewey WL, Selley DE, Zhang Y. Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivity. Journal of Medicinal Chemistry. 56: 9156-69. PMID 24144240 DOI: 10.1021/Jm4012214 |
0.351 |
|
| 2013 |
Llorente J, Withey S, Rivero G, Cunningham M, Cooke A, Saxena K, McPherson J, Oldfield S, Dewey WL, Bailey CP, Kelly E, Henderson G. Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons. Molecular Pharmacology. 84: 252-60. PMID 23716621 DOI: 10.1124/Mol.113.085936 |
0.341 |
|
| 2013 |
Hull LC, Gabra BH, Bailey CP, Henderson G, Dewey WL. Reversal of morphine analgesic tolerance by ethanol in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 345: 512-9. PMID 23528610 DOI: 10.1124/jpet.112.202184 |
0.367 |
|
| 2012 |
Yuan Y, Elbegdorj O, Chen J, Akubathini SK, Zhang F, Stevens DL, Beletskaya IO, Scoggins KL, Zhang Z, Gerk PM, Selley DE, Akbarali HI, Dewey WL, Zhang Y. Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4'-pyridyl)carboxamido]morphinan derivatives as peripheral selective μ opioid receptor Agents. Journal of Medicinal Chemistry. 55: 10118-29. PMID 23116124 DOI: 10.1021/Jm301247N |
0.409 |
|
| 2012 |
Smith TH, Grider JR, Dewey WL, Akbarali HI. Morphine decreases enteric neuron excitability via inhibition of sodium channels. Plos One. 7: e45251. PMID 23028881 DOI: 10.1371/Journal.Pone.0045251 |
0.32 |
|
| 2012 |
Ritter JK, Fang Y, Xia M, Li PL, Dewey WL. Contribution of acid sphingomyelinase in the periaqueductal gray region to morphine-induced analgesia in mice. Neuroreport. 23: 780-5. PMID 22825003 DOI: 10.1097/Wnr.0B013E3283571757 |
0.409 |
|
| 2012 |
Ross GR, Lichtman A, Dewey WL, Akbarali HI. Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice. Pharmacology. 90: 55-65. PMID 22759743 DOI: 10.1159/000339076 |
0.521 |
|
| 2012 |
Ritter JK, Li C, Xia M, Poklis JL, Lichtman AH, Abdullah RA, Dewey WL, Li PL. Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. The Journal of Pharmacology and Experimental Therapeutics. 342: 770-9. PMID 22685343 DOI: 10.1124/Jpet.112.196451 |
0.463 |
|
| 2012 |
Yuan Y, Stevens DL, Braithwaite A, Scoggins KL, Bilsky EJ, Akbarali HI, Dewey WL, Zhang Y. 6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 4731-4. PMID 22683223 DOI: 10.1016/J.Bmcl.2012.05.075 |
0.428 |
|
| 2012 |
Fitting S, Scoggins KL, Xu R, Dever SM, Knapp PE, Dewey WL, Hauser KF. Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice. European Journal of Pharmacology. 689: 96-103. PMID 22659585 DOI: 10.1016/J.Ejphar.2012.05.029 |
0.327 |
|
| 2012 |
Maguma HT, Dewey WL, Akbarali HI. Differences in the characteristics of tolerance to μ-opioid receptor agonists in the colon from wild type and β-arrestin2 knockout mice. European Journal of Pharmacology. 685: 133-40. PMID 22521552 DOI: 10.1016/J.Ejphar.2012.04.001 |
0.386 |
|
| 2012 |
Ross GR, Gade AR, Dewey WL, Akbarali HI. Opioid-induced hypernociception is associated with hyperexcitability and altered tetrodotoxin-resistant Na+ channel function of dorsal root ganglia. American Journal of Physiology. Cell Physiology. 302: C1152-61. PMID 22189556 DOI: 10.1152/Ajpcell.00171.2011 |
0.333 |
|
| 2012 |
Kang M, Maguma HT, Smith TH, Ross GR, Dewey WL, Akbarali HI. The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract. The Journal of Pharmacology and Experimental Therapeutics. 340: 567-76. PMID 22129596 DOI: 10.1124/Jpet.111.186320 |
0.396 |
|
| 2011 |
Yuan Y, Li G, He H, Stevens DL, Kozak P, Scoggins KL, Mitra P, Gerk PM, Selley DE, Dewey WL, Zhang Y. Characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as novel leads to development of mu opioid receptor selective antagonists. Acs Chemical Neuroscience. 2: 346-51. PMID 22816021 DOI: 10.1021/Cn2000348 |
0.368 |
|
| 2011 |
Hoot MR, Sim-Selley LJ, Selley DE, Scoggins KL, Dewey WL. Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus. Brain Research. 1406: 1-7. PMID 21762883 DOI: 10.1016/J.Brainres.2011.06.023 |
0.369 |
|
| 2010 |
McPherson J, Rivero G, Baptist M, Llorente J, Al-Sabah S, Krasel C, Dewey WL, Bailey CP, Rosethorne EM, Charlton SJ, Henderson G, Kelly E. μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization. Molecular Pharmacology. 78: 756-66. PMID 20647394 DOI: 10.1124/mol.110.066613 |
0.34 |
|
| 2010 |
Hull LC, Rabender C, Gabra BH, Zhang F, Li PL, Dewey WL. Role of CD38, a cyclic ADP-ribosylcyclase, in morphine antinociception and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 334: 1042-50. PMID 20551293 DOI: 10.1124/Jpet.110.169243 |
0.355 |
|
| 2010 |
Hoot MR, Sim-Selley LJ, Poklis JL, Abdullah RA, Scoggins KL, Selley DE, Dewey WL. Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice. Brain Research. 1339: 18-25. PMID 20380816 DOI: 10.1016/J.Brainres.2010.03.105 |
0.308 |
|
| 2010 |
Hull LC, Llorente J, Gabra BH, Smith FL, Kelly E, Bailey C, Henderson G, Dewey WL. The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacy. The Journal of Pharmacology and Experimental Therapeutics. 332: 1127-35. PMID 20008489 DOI: 10.1124/jpet.109.161455 |
0.396 |
|
| 2009 |
Bailey CP, Oldfield S, Llorente J, Caunt CJ, Teschemacher AG, Roberts L, McArdle CA, Smith FL, Dewey WL, Kelly E, Henderson G. Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons. British Journal of Pharmacology. 158: 157-64. PMID 19309357 DOI: 10.1111/j.1476-5381.2009.00140.x |
0.38 |
|
| 2009 |
Bailey CP, Llorente J, Gabra BH, Smith FL, Dewey WL, Kelly E, Henderson G. Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons. The European Journal of Neuroscience. 29: 307-18. PMID 19200236 DOI: 10.1111/j.1460-9568.2008.06573.x |
0.406 |
|
| 2009 |
Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists. Journal of Medicinal Chemistry. 52: 1416-27. PMID 19199782 DOI: 10.1021/Jm801272C |
0.355 |
|
| 2009 |
Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Corrections to design, synthesis, and biological evaluation of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as μ opioid receptor selective antagonists (Journal of Medicinal Chemistry (2009) 52, (1416) DOI 10.1021/jm801272c) Journal of Medicinal Chemistry. 52: 8057. DOI: 10.1021/Jm9016224 |
0.313 |
|
| 2008 |
Ross GR, Gabra BH, Dewey WL, Akbarali HI. Morphine tolerance in the mouse ileum and colon. The Journal of Pharmacology and Experimental Therapeutics. 327: 561-72. PMID 18682567 DOI: 10.1124/Jpet.108.143438 |
0.401 |
|
| 2008 |
Gabra BH, Bailey CP, Kelly E, Smith FL, Henderson G, Dewey WL. Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice. Brain Research. 1217: 70-7. PMID 18501877 DOI: 10.1016/j.brainres.2008.04.036 |
0.411 |
|
| 2008 |
Gabra BH, Smith FL, Navarro HA, Carroll FI, Dewey WL. mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo. Brain Research. 1187: 58-66. PMID 18022146 DOI: 10.1016/j.brainres.2007.10.007 |
0.435 |
|
| 2007 |
Gabra BH, Bailey CP, Kelly E, Sanders AV, Henderson G, Smith FL, Dewey WL. Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance. Brain Research. 1159: 86-93. PMID 17582387 DOI: 10.1016/j.brainres.2007.05.017 |
0.432 |
|
| 2007 |
Sim-Selley LJ, Scoggins KL, Cassidy MP, Smith LA, Dewey WL, Smith FL, Selley DE. Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance. British Journal of Pharmacology. 151: 1324-33. PMID 17572699 DOI: 10.1038/Sj.Bjp.0707328 |
0.421 |
|
| 2007 |
Gabra BH, Kessler FK, Ritter JK, Dewey WL, Smith FL. Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia. The Journal of Pharmacology and Experimental Therapeutics. 322: 186-94. PMID 17405869 DOI: 10.1124/jpet.107.120071 |
0.328 |
|
| 2007 |
Smith FL, Gabra BH, Smith PA, Redwood MC, Dewey WL. Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice. Pain. 127: 129-39. PMID 16965856 DOI: 10.1016/j.pain.2006.08.009 |
0.406 |
|
| 2006 |
Smith FL, Javed RR, Smith PA, Dewey WL, Gabra BH. PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 54: 474-80. PMID 17056270 DOI: 10.1016/j.phrs.2006.09.007 |
0.424 |
|
| 2006 |
Bailey CP, Smith FL, Kelly E, Dewey WL, Henderson G. How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance? Trends in Pharmacological Sciences. 27: 558-65. PMID 17000011 DOI: 10.1016/j.tips.2006.09.006 |
0.392 |
|
| 2006 |
Martin BR, Wiley JL, Beletskaya I, Sim-Selley LJ, Smith FL, Dewey WL, Cottney J, Adams J, Baker J, Hill D, Saha B, Zerkowski J, Mahadevan A, Razdan RK. Pharmacological characterization of novel water-soluble cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 318: 1230-9. PMID 16757541 DOI: 10.1124/Jpet.106.104109 |
0.615 |
|
| 2005 |
Dalton GD, Smith FL, Smith PA, Dewey WL. Protein Kinase A activity is increased in mouse lumbar spinal cord but not brain following morphine antinociceptive tolerance for 15 days. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 52: 204-10. PMID 16026714 DOI: 10.1016/j.phrs.2005.03.004 |
0.398 |
|
| 2005 |
Dalton GD, Smith FL, Smith PA, Dewey WL. Chronic Delta9-tetrahydrocannabinol treatment produces antinociceptive tolerance in mice without altering protein kinase A activity in mouse brain and spinal cord. Biochemical Pharmacology. 70: 152-60. PMID 15913565 DOI: 10.1016/j.bcp.2005.04.008 |
0.34 |
|
| 2005 |
Dalton GD, Smith FL, Smith PA, Dewey WL. Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI). Neuropharmacology. 48: 648-57. PMID 15814100 DOI: 10.1016/j.neuropharm.2004.12.006 |
0.385 |
|
| 2005 |
Wiley JL, Smith FL, Razdan RK, Dewey WL. Task specificity of cross-tolerance between Delta9-tetrahydrocannabinol and anandamide analogs in mice. European Journal of Pharmacology. 510: 59-68. PMID 15740725 DOI: 10.1016/J.Ejphar.2005.01.006 |
0.597 |
|
| 2004 |
Javed RR, Dewey WL, Smith PA, Smith FL. PKC and PKA inhibitors reverse tolerance to morphine-induced hypothermia and supraspinal analgesia in mice. European Journal of Pharmacology. 492: 149-57. PMID 15178359 DOI: 10.1016/j.ejphar.2004.03.061 |
0.389 |
|
| 2004 |
Smith FL, Smith PA, Dewey WL, Javed RR. Effects of mGlu1 and mGlu5 metabotropic glutamate antagonists to reverse morphine tolerance in mice. European Journal of Pharmacology. 492: 137-42. PMID 15178357 DOI: 10.1016/j.ejphar.2004.03.055 |
0.41 |
|
| 2003 |
Smith FL, Javed RR, Elzey MJ, Dewey WL. The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA. Brain Research. 985: 78-88. PMID 12957370 DOI: 10.1016/S0006-8993(03)03170-6 |
0.401 |
|
| 2002 |
Smith FL, Javed R, Elzey MJ, Welch SP, Selley D, Sim-Selley L, Dewey WL. Prolonged reversal of morphine tolerance with no reversal of dependence by protein kinase C inhibitors. Brain Research. 958: 28-35. PMID 12468027 DOI: 10.1016/S0006-8993(02)03394-2 |
0.422 |
|
| 1999 |
Smith FL, Lohmann AB, Dewey WL. Involvement of phospholipid signal transduction pathways in morphine tolerance in mice. British Journal of Pharmacology. 128: 220-6. PMID 10498855 DOI: 10.1038/sj.bjp.0702771 |
0.411 |
|
| 1999 |
Smith FL, Dombrowski DS, Dewey WL. Involvement of intracellular calcium in morphine tolerance in mice. Pharmacology, Biochemistry, and Behavior. 62: 381-8. PMID 9972707 DOI: 10.1016/S0091-3057(98)00168-3 |
0.306 |
|
| 1997 |
Welch SP, Smith FL, Dewey WL. Morphine tolerance-induced modulation of [3H]glyburide binding to mouse brain and spinal cord. Drug and Alcohol Dependence. 45: 47-53. PMID 9179506 DOI: 10.1016/S0376-8716(97)01343-4 |
0.351 |
|
| 1994 |
McLaughlin CR, Dewey WL. A comparison of the antinociceptive effects of opioid agonists in neonatal and adult rats in phasic and tonic nociceptive tests. Pharmacology, Biochemistry, and Behavior. 49: 1017-23. PMID 7886070 DOI: 10.1016/0091-3057(94)90258-5 |
0.358 |
|
| 1993 |
White CW, Ward CR, Dombrowski DS, Dunlow LD, Brase DA, Dewey WL. Effect of intrathecal morphine on the fate of glucose. Comparison with effects of insulin and xanthan gum in mice. Biochemical Pharmacology. 45: 459-64. PMID 8435095 DOI: 10.1016/0006-2952(93)90083-9 |
0.351 |
|
| 1993 |
Saxen MA, Welch SP, Dewey WL. The mouse paw withdrawal assay: a method for determining the effect of calcitonin gene-related peptide on cutaneous heat nociceptive latency time. Life Sciences. 53: 397-405. PMID 8336518 DOI: 10.1016/0024-3205(93)90643-H |
0.341 |
|
| 1993 |
Smith FL, Dewey WL. Endogenous dynorphin modulates calcium-mediated antinociception in mice. Pharmacology, Biochemistry, and Behavior. 45: 383-91. PMID 8101006 DOI: 10.1016/0091-3057(93)90255-R |
0.303 |
|
| 1991 |
Brase DA, Ward CR, Bey PS, Dewey WL. Antagonism of the morphine-induced locomotor activation of mice by fructose: comparison with other opiates and sugars, and sugar effects on brain morphine. Life Sciences. 49: 727-34. PMID 1875782 DOI: 10.1016/0024-3205(91)90105-K |
0.428 |
|
| 1991 |
Adams ML, Morris DL, Brase DA, Dewey WL. Stereoselective effect of morphine on antinociception and endogenous opioid peptide levels in plasma but not cerebrospinal fluid of dogs. Life Sciences. 48: 917-24. PMID 1671791 DOI: 10.1016/0024-3205(91)90039-E |
0.387 |
|
| 1991 |
McLaughlin CR, Dewey WL, Fanselow MS. Short- and long-term factors in tolerance to morphine-induced antinociception: Single or multiple mechanisms? Psychobiology. 19: 217-222. DOI: 10.3758/BF03332071 |
0.335 |
|
| 1990 |
Brase DA, Singha AK, Estrada U, Lux F, Dewey WL. Hypoglycemia induced by intrathecal opioids in mice: stereospecificity, drug specificity and effect of fasting. The Journal of Pharmacology and Experimental Therapeutics. 253: 899-904. PMID 2359029 |
0.309 |
|
| 1990 |
Compton DR, Dewey WL, Martin BR. Cannabis dependence and tolerance production. Advances in Alcohol & Substance Abuse. 9: 129-47. PMID 2165734 DOI: 10.1300/J251V09N01_08 |
0.462 |
|
| 1989 |
Tripathi HL, Dewey WL. Comparison of the effects of diisopropylfluorophosphate, sarin, soman, and tabun on toxicity and brain acetylcholinesterase activity in mice. Journal of Toxicology and Environmental Health. 26: 437-46. PMID 2709438 DOI: 10.1080/15287398909531267 |
0.333 |
|
| 1989 |
Brase DA, Myer EC, Dewey WL. Possible hyperendorphinergic pathophysiology of the Rett syndrome. Life Sciences. 45: 359-66. PMID 2475733 DOI: 10.1016/0024-3205(89)90620-6 |
0.332 |
|
| 1988 |
Lux F, Brase DA, Dewey WL. Antagonism of antinociception in mice by glucose and fructose: comparison of subcutaneous and intrathecal morphine. European Journal of Pharmacology. 146: 337-40. PMID 3371404 DOI: 10.1016/0014-2999(88)90312-3 |
0.359 |
|
| 1987 |
Estrada U, Brase DA, Martin BR, Dewey WL. Cardiovascular effects of delta 9- and delta 9(11)-tetrahydrocannabinol and their interaction with epinephrine. Life Sciences. 41: 79-87. PMID 3037218 DOI: 10.1016/0024-3205(87)90559-5 |
0.503 |
|
| 1987 |
Young R, Glennon RA, Dewey WL. Effects of pyrazolopyridines and a triazolopyridazine on the pentobarbital discriminative stimulus. Psychopharmacology. 93: 494-7. PMID 2893416 DOI: 10.1007/Bf00207241 |
0.333 |
|
| 1987 |
Brase DA, Han YH, Dewey WL. Effects of glucose and diabetes on binding of naloxone and dihydromorphine to opiate receptors in mouse brain. Diabetes. 36: 1173-7. PMID 2820820 DOI: 10.2337/Diab.36.10.1173 |
0.337 |
|
| 1986 |
Aceto MD, Bagley RS, Dewey WL, Fu TC, Martin BR. The spinal cord as a major site for the antinociceptive action of nicotine in the rat. Neuropharmacology. 25: 1031-6. PMID 3774124 DOI: 10.1016/0028-3908(86)90198-X |
0.449 |
|
| 1986 |
Aceto MD, Dewey WL, Portoghese PS, Takemori AE. Effects of beta-funaltrexamine (beta-FNA) on morphine dependence in rats and monkeys. European Journal of Pharmacology. 123: 387-93. PMID 3720824 DOI: 10.1016/0014-2999(86)90713-2 |
0.381 |
|
| 1986 |
Adams ML, Brase DA, Welch SP, Dewey WL. The role of endogenous peptides in the action of opioid analgesics. Annals of Emergency Medicine. 15: 1030-5. PMID 3526991 DOI: 10.1016/S0196-0644(86)80124-X |
0.361 |
|
| 1986 |
Young R, Glennon RA, Brase DA, Dewey WL. Potencies of diazepam metabolites in rats trained to discriminate diazepam. Life Sciences. 39: 17-20. PMID 3088348 DOI: 10.1016/0024-3205(86)90432-7 |
0.315 |
|
| 1985 |
Kachur JF, Rosemond R, Welch S, Bowman ER, Martin BR, Brase DA, Dewey WL. Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits. Life Sciences. 37: 2549-55. PMID 4079662 DOI: 10.1016/0024-3205(85)90613-7 |
0.547 |
|
| 1985 |
Widman M, Tucker S, Brase DA, Dewey WL. Cholinergic agents: antinociception without morphine type dependence in rats. Life Sciences. 36: 2007-15. PMID 4039782 DOI: 10.1016/0024-3205(85)90450-3 |
0.349 |
|
| 1985 |
Jorapur VS, Khalil ZH, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 28: 783-7. PMID 2989518 DOI: 10.1021/Jm00383A016 |
0.696 |
|
| 1985 |
Cobert BJ, Dewey WL, Stewart JK. Effects of branched-chain amino acids on beta-endorphin in the pituitary of the rat. Neuroscience Letters. 58: 339-42. PMID 2931626 DOI: 10.1016/0304-3940(85)90077-1 |
0.305 |
|
| 1984 |
Shook JE, Kallman MJ, Dewey WL. The discriminative stimulus properties of the R2 isomer of viminol. Pharmacology, Biochemistry, and Behavior. 20: 59-62. PMID 6546450 DOI: 10.1016/0091-3057(84)90101-1 |
0.353 |
|
| 1984 |
Tagashira E, Kachur JF, Carter WH, Dewey WL. Pentazocine-tripelennamine ("T's and Blues") substitution studies in morphine-dependent rodents. The Journal of Pharmacology and Experimental Therapeutics. 231: 97-101. PMID 6541694 DOI: 10.1016/B978-008055232-3.62389-X |
0.308 |
|
| 1984 |
Robertson LR, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Synthesis and pharmacological activity of some 9-substituted delta 8-tetrahydrocannabinol analogues. Journal of Medicinal Chemistry. 27: 550-2. PMID 6323713 DOI: 10.1021/Jm00370A023 |
0.688 |
|
| 1984 |
Shook JE, Kallman MJ, Martin BR, Dewey WL. Characterization of the interaction of pentazocine and tripelennamine: drug discrimination and mu-receptor binding assay. Pharmacology, Biochemistry, and Behavior. 21: 877-81. PMID 6097919 DOI: 10.1016/S0091-3057(84)80068-4 |
0.517 |
|
| 1984 |
Martin BR, Kallman MJ, Kaempf GF, Harris LS, Dewey WL, Razdan RK. Pharmacological potency of R- and S-3'-hydroxy-delta 9-tetrahydrocannabinol: additional structural requirement for cannabinoid activity. Pharmacology, Biochemistry, and Behavior. 21: 61-5. PMID 6087379 DOI: 10.1016/0091-3057(84)90131-X |
0.681 |
|
| 1984 |
ROBERTSON LR, DUFFLEY RP, RAZDAN RK, MARTIN BR, HARRIS LS, DEWEY WL. ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF SOME 9-SUBSTITUTED Δ8-TETRAHYDROCANNABINOL (THC) ANALOGS Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198438203 |
0.585 |
|
| 1983 |
Welch SP, Vocci FJ, Dewey WL. Antinociceptive and lethal effects of intraventricularly administered barium and strontium: antagonism by atropine sulfate or naloxone hydrochlorine. Life Sciences. 33: 359-64. PMID 6877028 DOI: 10.1016/S0024-3205(83)80009-5 |
0.398 |
|
| 1983 |
Kiang JG, Dewey WL, Wei ET. Tolerance to morphine bradycardia in the rat. The Journal of Pharmacology and Experimental Therapeutics. 226: 187-91. PMID 6864538 |
0.312 |
|
| 1983 |
Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. Pharmachology The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species Pain. 17: 393. DOI: 10.1016/0304-3959(83)90171-9 |
0.444 |
|
| 1983 |
HANDRICK GR, DUFFLEY RP, LAMBERT G, MURPHY JG, DALZELL HC, HOWES JF, RAZDAN RK, MARTIN BR, HARRIS LS, DEWEY WL. ChemInform Abstract: 3′-HYDROXY- AND (.+-.)-3′,11-DIHYDROXY-Δ9-TETRAHYDROCANNABINOL: (THC) BIOLOGICALLY ACTIVE METABOLITES OF Δ9-TETRAHYDROCANNABINOL Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198322251 |
0.568 |
|
| 1982 |
Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species. Life Sciences. 31: 1741-3. PMID 7154834 DOI: 10.1016/0024-3205(82)90199-0 |
0.553 |
|
| 1982 |
Aceto MD, Dewey WL, Chang JK, Lee NM. Dynorphin-(1-13): effects in nontolerant and morphine-dependent rhesus monkeys. European Journal of Pharmacology. 83: 139-42. PMID 6889974 DOI: 10.1016/0014-2999(82)90299-0 |
0.39 |
|
| 1982 |
Handrick GR, Duffley RP, Lambert G, Murphy JG, Dalzell HC, Howes JF, Razdan RK, Martin BR, Harris LS, Dewey WL. 3'-Hydroxy- and (+/-)-3',11-dihydroxy-delta 9-tetrahydrocannabinol: biologically active metabolites of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 25: 1447-50. PMID 6296389 |
0.675 |
|
| 1982 |
Dewey WL, Fu TC, Ohlsson A, Bowman E, Martin BR. Evidence for the release of endogenous opiates by morphine. Nida Research Monograph. 41: 60-6. PMID 6289120 |
0.422 |
|
| 1982 |
Ohlsson AE, Fu TC, Jones D, Martin BR, Dewey WL. Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice. The Journal of Pharmacology and Experimental Therapeutics. 221: 362-7. PMID 6281413 |
0.399 |
|
| 1982 |
Snow AE, Tucker SM, Dewey WL. The role of neurotransmitters in stress-induced antinociception (SIA). Pharmacology, Biochemistry, and Behavior. 16: 47-50. PMID 6120525 DOI: 10.1016/0091-3057(82)90011-9 |
0.339 |
|
| 1981 |
Pedigo NW, Dewey WL. Comparison of the antinociceptive activity of intraventricularly administered acetylcholine to narcotic antinociception. Neuroscience Letters. 26: 85-90. PMID 7290542 DOI: 10.1016/0304-3959(82)90041-0 |
0.452 |
|
| 1981 |
Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies of new compounds in the rhesus monkey (1980). Nida Research Monograph. 34: 297-326. PMID 6783944 |
0.565 |
|
| 1981 |
Johnson KM, Dewey WL, Bloom AS. Adrenalectomy reverses the effects of delta-9-THC on mouse brain 5-hydroxytryptamine turnover. Pharmacology. 23: 223-9. PMID 6275421 DOI: 10.1159/000137553 |
0.743 |
|
| 1981 |
Chau TT, Dewey WL. Effects of the intracerebroventricular injection of antinociceptive doses of acetylcholine on the stereospecific binding of 3H-dihydromorphine. Life Sciences. 29: 2149-56. PMID 6275221 DOI: 10.1016/0024-3205(81)90484-7 |
0.358 |
|
| 1981 |
Martin BR, Balster RL, Razdan RK, Harris LS, Dewey WL. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols. Life Sciences. 29: 565-74. PMID 6268916 DOI: 10.1016/0024-3205(81)90434-3 |
0.672 |
|
| 1981 |
End DW, Carchman RA, Dewey WL. Neurochemical correlates of chlordecone neurotoxicity. Journal of Toxicology and Environmental Health. 8: 707-18. PMID 6175764 DOI: 10.1080/15287398109530107 |
0.305 |
|
| 1980 |
Fu TC, Halenda SP, Dewey WL. The effect of hypophysectomy on acupuncture analgesia in the mouse. Brain Research. 202: 33-9. PMID 7427744 DOI: 10.1016/S0006-8993(80)80032-1 |
0.416 |
|
| 1980 |
Tripathi HL, Vocci FJ, Dewey WL. Effect of antinociceptive doses of oxotremorine on mouse brain acetylcholine turnover rate. Life Sciences. 27: 2055-62. PMID 7207008 DOI: 10.1016/0024-3205(80)90484-1 |
0.302 |
|
| 1980 |
Alozie SO, Martin BR, Harris LS, Dewey WL. 3H-delta 9-Tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: penetration and regional distribution in rat brain. Pharmacology, Biochemistry, and Behavior. 12: 217-21. PMID 6246544 DOI: 10.1016/0091-3057(80)90359-7 |
0.673 |
|
| 1979 |
Segreti A, Vocci FJ, Dewey WL. Antagonism of barium chloride lethality by atropine and naloxone analysis by a multivariate logistic model. Toxicology and Applied Pharmacology. 50: 25-30. PMID 494298 DOI: 10.1016/0041-008X(79)90488-5 |
0.375 |
|
| 1979 |
Fu TC, Dewey WL. Morphine antinociception: evidence for the release of endogenous substance(s). Life Sciences. 25: 53-60. PMID 481121 DOI: 10.1016/0024-3205(79)90489-2 |
0.372 |
|
| 1979 |
Wilson RS, May EL, Dewey WL. Some 9-hydroxycannabinoid-like compounds. Synthesis and evaluation of analgesic and behavioral properties. Journal of Medicinal Chemistry. 22: 886-8. PMID 448688 DOI: 10.1021/Jm00193A027 |
0.326 |
|
| 1979 |
Wilson RS, Martin BR, Dewey WL. Some 11-substituted tetrahydrocannabinols. Synthesis and comparison with the potent cannabinoid metabolites 11-hydroxytetrahydrocannabinols. Journal of Medicinal Chemistry. 22: 879-82. PMID 448686 DOI: 10.1021/JM00193A025 |
0.497 |
|
| 1979 |
Aceto MD, Martin BR, Uwaydah IM, May EL, Harris LS, Izazola-Conde C, Dewey WL, Bradshaw TJ, Vincek WC. Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine. Journal of Medicinal Chemistry. 22: 174-7. PMID 423195 DOI: 10.1021/JM00188A009 |
0.642 |
|
| 1979 |
Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies on new compounds in the rhesus monkey (1979). Nida Research Monograph. 27: 330-50. PMID 121356 |
0.565 |
|
| 1979 |
Rosecrans JA, Campbell OL, Dewey WL, Harris LS. Discriminative stimulus and neurochemical mechanism of cathinone: a preliminary study. Nida Research Monograph. 27: 328-9. PMID 121355 |
0.531 |
|
| 1978 |
Dewey WL, Poddar MK, Johnson KM. The effects of cannabinoids on rat brain synaptosomes. Advances in the Biosciences. 22: 343-9. PMID 756834 DOI: 10.1016/B978-0-08-023759-6.50029-9 |
0.707 |
|
| 1978 |
McConnell WR, Dewey WL, Harris LS, Borzelleca JF. A study of the effect of delta 9-tetrahydrocannabinol (delta 9-THC) on mammalian salivary flow. The Journal of Pharmacology and Experimental Therapeutics. 206: 567-73. PMID 702321 |
0.559 |
|
| 1978 |
Johnson KM, Dewey WL. Effects of delta9-THC on the synaptosomal uptake of 3H-tryptophan and 3H-choline. Pharmacology. 17: 83-7. PMID 684080 DOI: 10.1159/000136839 |
0.707 |
|
| 1978 |
Patrick GA, Dewey WL, Huger FP, Daves ED, Harris LS. Disposition of morphine in chronically infused rats: relationship to antinociception and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 205: 556-62. PMID 660529 |
0.652 |
|
| 1978 |
Johnson KM, Dewey WL, Ritter KS, Beckner JS. Cannabinoid effects on plasma corticosterone and uptake of 3H-corticosterone by mouse brain. European Journal of Pharmacology. 47: 303-10. PMID 631183 DOI: 10.1016/0014-2999(78)90238-8 |
0.695 |
|
| 1978 |
Lujan M, Chau-Pham TT, Aceto MD, Dewey WL. The effect of sodium ion on antinociception and opiate binding in vivo. Life Sciences. 23: 1431-9. PMID 213670 DOI: 10.1016/0024-3205(78)90124-8 |
0.407 |
|
| 1978 |
Chau-Pham TT, King G, Dewey WL. Sodium-induced alterations of opiate effects on the binding of 3H-dihydromorphine to mouse brain homogenates. Life Sciences. 23: 1293-9. PMID 213669 DOI: 10.1016/0024-3205(78)90508-8 |
0.373 |
|
| 1978 |
Fraser HF, Kay DC, Yeh SY, Gorodetzky CW, Dewey WL. Possible effects of normetabolites on the subjective and reinforcing characteristics of opioids in animals and man. Drug and Alcohol Dependence. 3: 301-18. PMID 101364 DOI: 10.1016/0376-8716(78)90001-7 |
0.4 |
|
| 1978 |
Bloom AS, Dewey WL. A comparison of some pharmacological actions of morphine and delta9-tetrahydrocannabinol in the mouse. Psychopharmacology. 57: 243-8. PMID 97703 DOI: 10.1007/Bf00426745 |
0.422 |
|
| 1978 |
Martin BR, Montgomery J, Dewey WL, Harris LS. Alterations in the pharmacokinetics of 3H-delta9-tetrahydrocannabinol in mice by bacterial endotoxin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 282-7. PMID 26549 |
0.68 |
|
| 1978 |
Fraser H, Kay D, Gorodetzky C, Yeh S, Dewey W. Evidence for the importance of N-dealkylation in opioid pharmacology Drug and Alcohol Dependence. 3: 1-22. DOI: 10.1016/0376-8716(78)90031-5 |
0.384 |
|
| 1977 |
Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses. Research Communications in Chemical Pathology and Pharmacology. 17: 457-70. PMID 897339 |
0.635 |
|
| 1977 |
Adams MD, Earnhardt JT, Martin BR, Harris LS, Dewey WL, Razdan RK. A cannabinoid with cardiovascular activity but no overt behavioral effects. Experientia. 33: 1204-5. PMID 891878 DOI: 10.1007/Bf01922330 |
0.678 |
|
| 1977 |
Ford RD, Balster RL, Dewey WL, Beckner JS. delta 9-THC and 11-OH-delta 9-THC: behavioral effects and relationship to plasma and brain levels. Life Sciences. 20: 1993-2003. PMID 881943 DOI: 10.1016/0024-3205(77)90178-3 |
0.362 |
|
| 1977 |
Bloom AS, Dewey WL, Harris LS, Brosius KK. 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine. The Journal of Pharmacology and Experimental Therapeutics. 200: 263-70. PMID 839438 |
0.629 |
|
| 1977 |
Martin BR, Dewey WL, Aceto MD, Adams MD, Earnhardt JT, Carney JM. A potent antinociceptive cannabinoid which lacks opiate substitution properties in monkeys. Research Communications in Chemical Pathology and Pharmacology. 16: 187-90. PMID 402685 |
0.441 |
|
| 1977 |
Martin BR, Dewey WL, Chau-Pham T, Prnage AJ. Interactions of thyrotropin releasing hormone and morphine sulfate in rodents. Life Sciences. 20: 715-22. PMID 402526 DOI: 10.1016/0024-3205(77)90477-5 |
0.545 |
|
| 1977 |
Bradley SG, Munson AE, Dewey WL, Harris LS. Enhanced susceptibility of mice to combinations of delta 9-tetrahydrocannabinol and live or killed gram-negative bacteria. Infection and Immunity. 17: 325-9. PMID 330405 |
0.579 |
|
| 1977 |
Chau-Pham TT, Dewey WL. A comparative study of the effect of methionine enkephalin upon the stereospecific binding of an opiate agonist and an antagonist in mice and rats. Life Sciences. 21: 1337-42. PMID 200814 DOI: 10.1016/0024-3205(77)90016-9 |
0.354 |
|
| 1976 |
Dionne RA, Dewey WL, Joy E. A survey of the teaching of pain control at the predoctoral level. Anesthesia Progress. 23: 152-4. PMID 19598503 |
0.423 |
|
| 1976 |
Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol tissue and subcellular distribution in the central nervous system and tissue distribution in peripheral organs of tolerant and nontolerant dogs. The Journal of Pharmacology and Experimental Therapeutics. 196: 128-44. PMID 1246007 |
0.651 |
|
| 1976 |
Atkinson ER, Battista SP, Ary IE, Richardson DG, Harris LS, Dewey WL. Derivatives of apomorphine and of other N-substituted norapomorphines. Journal of Pharmaceutical Sciences. 65: 1682-5. PMID 994002 DOI: 10.1002/Jps.2600651129 |
0.585 |
|
| 1976 |
Wilson RS, May EL, Martin BR, Dewey WL. 9 Nor 9 hydroxyhexahydrocannabinols. Synthesis, some behavioral and analgesic properties, and comparison with the tetrahydrocannabinols Journal of Medicinal Chemistry. 19: 1165-1167. PMID 978681 DOI: 10.1002/Chin.197652236 |
0.499 |
|
| 1976 |
Day AR, Luján M, Dewey WL, Harris LS, Radding JA, Freer RJ. Structure-activity relationships of enkephalins in the stimulated guinea pig ileum. Research Communications in Chemical Pathology and Pharmacology. 14: 597-603. PMID 959662 |
0.584 |
|
| 1976 |
Johnson KM, Dewey WL, Harris LS. Some structural requirements for inhibition of high-affinity synaptosomal serotonin uptake by cannabinoids. Molecular Pharmacology. 12: 345-52. PMID 934055 |
0.551 |
|
| 1976 |
Dewey WL, Johnson KM, Bloom AS. Interactions of active constituents of marihuana with other drugs in the neuron. Annals of the New York Academy of Sciences. 281: 190-7. PMID 798522 DOI: 10.1111/J.1749-6632.1976.Tb27930.X |
0.665 |
|
| 1976 |
Forbes JE, Dewey WL. The effects of narcotic analgesics and narcotic antagonists on ganglionic transmission in the rat. Life Sciences. 19: 401-7. PMID 183075 DOI: 10.1016/0024-3205(76)90045-X |
0.405 |
|
| 1976 |
Bloom AS, Dewey WL, Harris LS, Brosius KK. The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines. The Journal of Pharmacology and Experimental Therapeutics. 198: 33-41. PMID 6793 |
0.661 |
|
| 1976 |
Adams MD, Earnhardt JT, Dewey WL, Harris LS. Vasoconstrictor actions of delta8- and delta9-tetrahydrocannabinol in the rat. The Journal of Pharmacology and Experimental Therapeutics. 196: 649-56. PMID 4606 |
0.61 |
|
| 1976 |
Pedigo NW, Dewey WL, Harris LS. Pharmacology Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice Pain. 2: 86. DOI: 10.1016/0304-3959(76)90055-5 |
0.652 |
|
| 1975 |
Martin BR, Dewey WL, Harris LS, Beckner J. Marihuana-like activity of new synthetic tetrahydrocannabinols. Pharmacology, Biochemistry, and Behavior. 3: 849-53. PMID 1208625 DOI: 10.1016/0091-3057(75)90116-1 |
0.71 |
|
| 1975 |
Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA. Antineoplastic activity of cannabinoids. Journal of the National Cancer Institute. 55: 597-602. PMID 1159836 |
0.601 |
|
| 1975 |
Patrick GA, Dewey WL, Spaulding TC, Harris LS. Relationship of brain morphine levels to analgesic activity in acutely treated mice and rats and in pellet implanted mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 876-83. PMID 1151736 |
0.647 |
|
| 1975 |
Pedigo NW, Dewey WL, Harris LS. Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 845-52. PMID 1151733 |
0.67 |
|
| 1975 |
Dewey WL, Cocolas G, Daves E, Harris LS. Stereospecificity of intraventricularly administered acetylmethylcholine antinociception. Life Sciences. 17: 9-10. PMID 1143014 DOI: 10.1016/0024-3205(75)90224-6 |
0.68 |
|
| 1975 |
Chipkin RE, Dewey WL, Harris LS, Lowenthal W. Effect of propranolol on antinociceptive and withdrawal characteristics of morphine. Pharmacology, Biochemistry, and Behavior. 3: 843-7. PMID 1800 DOI: 10.1016/0091-3057(75)90115-X |
0.683 |
|
| 1975 |
Martin BR, Dewey WL, Harris LS, Beckner J, Wilson RS, May EL. Marihuana-like activity of new synthetic tetrahydrocannabinols Pharmacology, Biochemistry and Behavior. 3: 849-853. DOI: 10.1016/0091-3057(75)90116-1 |
0.555 |
|
| 1973 |
Kosersky DS, Dewey WL, Harris LS. Antipyretic, analgesic and anti-inflammatory effects of delta 9-tetrahydrocannabinol in the rat. European Journal of Pharmacology. 24: 1-7. PMID 4756165 DOI: 10.1016/0014-2999(73)90107-6 |
0.613 |
|
| 1973 |
Chau TT, Dewey WL, Harris LS. Mechanism of the synergistic lethality between pentazocine and vasopressin in the rat. The Journal of Pharmacology and Experimental Therapeutics. 186: 288-96. PMID 4719781 |
0.56 |
|
| 1973 |
Turk RF, Dewey WL, Harris LS. Excretion of trans- 9 -tetrahydrocannabinol and its metabolites in intact and bile duct-cannulated rats. Journal of Pharmaceutical Sciences. 62: 737-40. PMID 4705677 DOI: 10.1002/Jps.2600620506 |
0.605 |
|
| 1973 |
Dewey WL, McMillan DE, Harris LS, Turk RF. Distribution of radioactivity in brain of tolerant and nontolerant pigeons treated with 3 H- 9 -tetrahydrocannabinol. Biochemical Pharmacology. 22: 399-405. PMID 4687135 DOI: 10.1016/0006-2952(73)90420-6 |
0.593 |
|
| 1973 |
McMillan DE, Dewey WL, Turk RF, Harris LS, McNeil JH. Blood levels of 3 H- 9 -tetrahydrocannabinol and its metabolites in tolerant and nontolerant pigeons. Biochemical Pharmacology. 22: 383-97. PMID 4687134 DOI: 10.1016/0006-2952(73)90419-X |
0.594 |
|
| 1972 |
Dewey WL, Harris LS, Kennedy JS. Some pharmacological and toxicological effects of 1-trans- 8 and 1-trans- 9 -tetrahydrocannabinol in laboratory rodents. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 196: 133-45. PMID 5059359 |
0.579 |
|
| 1972 |
Dewey WL, Jenkins J, O'Rourke T, Harris LS. The effects of chronic administration of trans- 9 -tetrahydrocannabinol on behavior and the cardiovascular system of dogs. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 198: 118-31. PMID 5053234 |
0.576 |
|
| 1972 |
Zitko BA, Howes JF, Razdan RK, Dalzell BC, Dalzell HC, Sheehan JC, Pars HG, Dewey WL, Harris LS. Water-soluble derivatives of 1 -tetrahydrocannabinol. Science (New York, N.Y.). 177: 442-4. PMID 5043146 DOI: 10.1126/science.177.4047.442 |
0.56 |
|
| 1972 |
Spaulding TC, Ford RD, Dewey WL, McMillan DE, Harris LS. Some pharmacological effects of phenitrone and its interaction with 9 -THC. European Journal of Pharmacology. 19: 310-7. PMID 4640854 DOI: 10.1016/0014-2999(72)90096-9 |
0.642 |
|
| 1972 |
ZITKO BA, HOWES JF, RAZDAN RK, DALZELL BC, DALZELL HC, SHEEHAN JC, PARS HG, DEWEY WL, HARRIS LS. ChemInform Abstract: WASSERLOESLICHE DERIVATE VON DELTA(1)-TETRAHYDROCANNABINOL Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/chin.197250288 |
0.573 |
|
| 1971 |
McMillan DE, Dewey WL, Harris LS. CHARACTERISTICS OF TETRAHYDROCANNABINOL TOLERANCE Annals of the New York Academy of Sciences. 191: 83-99. DOI: 10.1111/J.1749-6632.1971.Tb13990.X |
0.563 |
|
| 1970 |
Howes JF, Harris LS, Dewey WL. The effect of morphine, nalorphine, naloxone, pentazocine, cyclazocine and oxotremorine on the synthesis and release of acetylcholine by mouse cerebral cortex slices in vitro. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 184: 267-76. PMID 5453231 |
0.614 |
|
| 1970 |
Dewey WL, Harris LS, Howes JF, Kennedy JS, Granchelli FE, Pars HG, Razdan RK. Pharmacology of some marijuana constituents and 2 heterocyclic analogues. Nature. 226: 1265-7. PMID 5422606 DOI: 10.1038/2261265A0 |
0.577 |
|
| 1970 |
Dewey WL, Harris LS, Howes JF, Nuite JA. The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests. The Journal of Pharmacology and Experimental Therapeutics. 175: 435-42. PMID 4394803 |
0.638 |
|
| 1970 |
Dewey WL, Peng TC, Harris LS. The effect of 1-trans-delta 9-tetrahydrocannabinol on the hypothalamo-hypophyseal-adrenal axis of rats. European Journal of Pharmacology. 12: 382-4. PMID 4322071 DOI: 10.1016/0014-2999(70)90094-4 |
0.597 |
|
| 1969 |
Howes JF, Harris LS, Dewey WL, Voyda CA. Brain acetylcholine levels and inhibition of the tail-flick reflex in mice. The Journal of Pharmacology and Experimental Therapeutics. 169: 23-8. PMID 5804609 |
0.595 |
|
| 1969 |
Dewey WL, Harris LS, Howes JF, Kennedy JS, Nuite JA, Hayhurst V. The effects of narcotic-antagonist analgesics on rat brain cholinesterases. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 182: 471-80. PMID 5371206 |
0.603 |
|
| 1969 |
Harris LS, Dewey WL, Howes JF, Kennedy JS, Pars H. Narcotic-antagonist analgesics: interactions with cholinergic systems. The Journal of Pharmacology and Experimental Therapeutics. 169: 17-22. PMID 4389919 |
0.563 |
|
| 1969 |
Dewey WL, Snyder JW, Harris LS, Howes JF. The effect of narcotics and narcotic antagonists on the tail-flick response in spinal mice. The Journal of Pharmacy and Pharmacology. 21: 548-50. PMID 4389723 DOI: 10.1111/J.2042-7158.1969.Tb08312.X |
0.59 |
|
| 1967 |
Harris LS, Pierson AK, Dembinski JR, Dewey WL. The pharmacology of (minus)-3-hydroxy-N-cyclopropylmethylmorphinan (cyclorphan). Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 165: 112-26. PMID 4382141 |
0.539 |
|
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