| Year |
Citation |
Score |
| 2020 |
Zhu MJ, Shi J, Chen Y, Huang G, Zhu XW, Zhang S, Huang XF, Song GQ, Zhang HT, Ke HM, O'Donnell JM, Wang LQ, Xu Y. Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior. Psychopharmacology. PMID 32926224 DOI: 10.1007/S00213-019-05401-1 |
0.371 |
|
| 2020 |
Hou X, Rong C, Wang F, Liu X, Sun Y, Zhang HT. GABAergic System in Stress: Implications of GABAergic Neuron Subpopulations and the Gut-Vagus-Brain Pathway. Neural Plasticity. 2020: 8858415. PMID 32802040 DOI: 10.1155/2020/8858415 |
0.326 |
|
| 2020 |
Wang H, Zhang FF, Xu Y, Fu HR, Dan Wan X, Wang L, Chen W, Xu XY, Gao YF, Zhang JG, Zhang HT. The phosphodiesterase-4 inhibitor roflumilast, a potential treatment for the comorbidity of memory loss and depression in Alzheimer's disease: a preclinical study in APP/PS1 transgenic mice. The International Journal of Neuropsychopharmacology. PMID 32645141 DOI: 10.1093/Ijnp/Pyaa048 |
0.401 |
|
| 2020 |
Pei YA, Davies J, Zhang M, Zhang HT. The Role of Synaptic Dysfunction in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32417776 DOI: 10.3233/Jad-191334 |
0.311 |
|
| 2020 |
Huang Y, Huang W, Huang Y, Song P, Zhang M, Zhang HT, Pan S, Hu Y. Cdk5 Inhibitory Peptide Prevents Loss of Neurons and Alleviates Behavioral Changes in p25 Transgenic Mice. Journal of Alzheimer's Disease : Jad. PMID 32144987 DOI: 10.3233/Jad-191098 |
0.305 |
|
| 2020 |
Hou X, Xu L, Liu X, Zhang H. Effects of osthole microemulsion by nasal administration on the cholinergic pathway in mice treated with scopolamine The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08639 |
0.316 |
|
| 2019 |
Cui SY, Yang MX, Zhang YH, Zheng V, Zhang HT, Gurney ME, Xu Y, O'Donnell JM. Protection from amyloid β peptide-induced memory, biochemical and morphological deficits by a phosphodiesterase-4D (PDE4D) allosteric inhibitor. The Journal of Pharmacology and Experimental Therapeutics. PMID 31488603 DOI: 10.1124/Jpet.119.259986 |
0.428 |
|
| 2019 |
Gao Y, Yan Y, Fang Q, Zhang N, Kumar G, Zhang J, Song LJ, Yu J, Zhao L, Zhang HT, Ma CG. The Rho kinase inhibitor fasudil attenuates Aβ-induced apoptosis via the ASK1/JNK signal pathway in primary cultures of hippocampal neurons. Metabolic Brain Disease. PMID 31482248 DOI: 10.1007/S11011-019-00487-0 |
0.345 |
|
| 2019 |
Xu M, Huang Y, Song P, Huang Y, Huang W, Zhang HT, Hu Y. AAV9-Mediated Cdk5 Inhibitory Peptide Reduces Hyperphosphorylated Tau and Inflammation and Ameliorates Behavioral Changes Caused by Overexpression of p25 in the Brain. Journal of Alzheimer's Disease : Jad. PMID 31256130 DOI: 10.3233/Jad-190099 |
0.318 |
|
| 2019 |
Zhu X, Li W, Li Y, Xu W, Yuan Y, Zheng V, Zhang HT, O'Donnell JM, Xu Y, Yin X. The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition. Neuropharmacology. PMID 31026437 DOI: 10.1016/J.Neuropharm.2019.04.022 |
0.388 |
|
| 2019 |
Chen L, Cui S, Yu H, Li G, Liu N, Wu Q, Zhang HT, O'Donnell JM, Wang G, Xu Y. Reduced phosphodiesterase-2 activity in the amygdala results in anxiolytic-like effects on behavior in mice. Journal of Psychopharmacology (Oxford, England). 269881119832753. PMID 30835157 DOI: 10.1177/0269881119832753 |
0.345 |
|
| 2019 |
Zhang H, Wang H, Zhang F, Li B, Zhou Y, Yu H, Xu Y, O'Donnell J. Inhibition of phosphodiesterase‐4D reverses memory deficits and depression‐like effects via cAMP signaling in mouse models of Alzheimer's disease The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.806.1 |
0.389 |
|
| 2018 |
Yan Y, Yu J, Gao Y, Kumar G, Guo M, Zhao Y, Fang Q, Zhang H, Yu J, Jiang Y, Zhang HT, Ma CG. Therapeutic potentials of the Rho kinase inhibitor Fasudil in experimental autoimmune encephalomyelitis and the related mechanisms. Metabolic Brain Disease. PMID 30552558 DOI: 10.1007/S11011-018-0355-7 |
0.339 |
|
| 2018 |
Huang X, Xiaokaiti Y, Yang J, Pan J, Li Z, Luria V, Li Y, Song G, Zhu X, Zhang HT, O'Donnell JM, Xu Y. Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior. Neuropharmacology. PMID 30268520 DOI: 10.1016/J.Neuropharm.2018.09.039 |
0.362 |
|
| 2018 |
Zhang F, Zhang JG, Yang W, Xu P, Xiao YL, Zhang HT. 6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 107: 1523-1529. PMID 30257370 DOI: 10.1016/J.Biopha.2018.08.136 |
0.362 |
|
| 2018 |
Zhang C, Xu Y, Chowdhary A, Fox D, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30131563 DOI: 10.1038/S41386-018-0178-6 |
0.301 |
|
| 2018 |
Xu Y, Zhu N, Xu W, Ye H, Liu K, Wu F, Zhang M, Ding Y, Zhang C, Zhang H, O'Donnell J, Pan J. Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling. Frontiers in Aging Neuroscience. 10: 204. PMID 30087608 DOI: 10.3389/Fnagi.2018.00204 |
0.459 |
|
| 2018 |
Yu J, Yan Y, Gu Q, Kumar G, Yu H, Zhao Y, Liu C, Gao Y, Chai Z, Chumber J, Xiao BG, Zhang GX, Zhang HT, Jiang Y, Ma CG. Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer's Disease-Related Changes Through the Regulation of the Peripheral Immune System. Frontiers in Aging Neuroscience. 10: 216. PMID 30061826 DOI: 10.3389/Fnagi.2018.00216 |
0.32 |
|
| 2018 |
Shi J, Liu H, Pan J, Chen J, Zhang N, Liu K, Fei N, O'Donnell JM, Zhang HT, Xu Y. Inhibition of phosphodiesterase 2 by Bay 60-7550 decreases ethanol intake and preference in mice. Psychopharmacology. PMID 29876622 DOI: 10.1007/S00213-018-4934-4 |
0.355 |
|
| 2018 |
Huang XF, Jiang WT, Liu L, Song FC, Zhu X, Shi GL, Ding SM, Ke HM, Wang W, O'Donnell JM, Zhang HT, Luo HB, Wan YQ, Song GQ, Xu Y. A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling. Cns Neuroscience & Therapeutics. PMID 29722134 DOI: 10.1111/Cns.12864 |
0.394 |
|
| 2018 |
Liu L, Zheng J, Huang XF, Zhu X, Ding SM, Ke HM, O'Donnell JM, Zhang HT, Song GQ, Xu Y. The neuroprotective and antidepressant-like effects of Hcyb1, a novel selective PDE2 inhibitor. Cns Neuroscience & Therapeutics. PMID 29704309 DOI: 10.1111/Cns.12863 |
0.355 |
|
| 2018 |
Wen RT, Zhang FF, Zhang HT. Cyclic nucleotide phosphodiesterases: potential therapeutic targets for alcohol use disorder. Psychopharmacology. PMID 29663017 DOI: 10.1007/S00213-018-4895-7 |
0.304 |
|
| 2017 |
Wen RT, Liang JH, Zhang HT. Targeting Phosphodiesterases in Pharmacotherapy for Substance Dependence. Advances in Neurobiology. 17: 413-444. PMID 28956341 DOI: 10.1007/978-3-319-58811-7_15 |
0.395 |
|
| 2017 |
Zhang C, Lueptow LM, Zhang HT, O'Donnell JM, Xu Y. The Role of Phosphodiesterase-2 in Psychiatric and Neurodegenerative Disorders. Advances in Neurobiology. 17: 307-347. PMID 28956338 DOI: 10.1007/978-3-319-58811-7_12 |
0.508 |
|
| 2017 |
Hansen RT, Zhang HT. The Past, Present, and Future of Phosphodiesterase-4 Modulation for Age-Induced Memory Loss. Advances in Neurobiology. 17: 169-199. PMID 28956333 DOI: 10.1007/978-3-319-58811-7_7 |
0.731 |
|
| 2017 |
Hu Y, Pan S, Zhang HT. Interaction of Cdk5 and cAMP/PKA Signaling in the Mediation of Neuropsychiatric and Neurodegenerative Diseases. Advances in Neurobiology. 17: 45-61. PMID 28956329 DOI: 10.1007/978-3-319-58811-7_3 |
0.357 |
|
| 2017 |
Gong MF, Wen RT, Xu Y, Pan JC, Fei N, Zhou YM, Xu JP, Liang JH, Zhang HT. Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents. Psychopharmacology. PMID 28748375 DOI: 10.1007/S00213-017-4697-3 |
0.33 |
|
| 2017 |
Liu X, Hao PD, Yang MF, Sun JY, Mao LL, Fan CD, Zhang ZY, Li DW, Yang XY, Sun BL, Zhang HT. The phosphodiesterase-4 inhibitor roflumilast decreases ethanol consumption in C57BL/6J mice. Psychopharmacology. PMID 28477089 DOI: 10.1007/S00213-017-4631-8 |
0.339 |
|
| 2017 |
He Y, Pan S, Xu M, He R, Huang W, Song P, Huang J, Zhang HT, Hu Y. Adeno-associated viral 9-mediated Cdk5 inhibitory peptide reverses pathologic changes and behavioral deficits in the Alzheimer's disease mouse model. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28420695 DOI: 10.1096/Fj.201700064R |
0.398 |
|
| 2017 |
Zhang C, Xu Y, Zhang HT, Gurney ME, O'Donnell JM. Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System. Scientific Reports. 7: 40115. PMID 28054669 DOI: 10.1038/Srep40115 |
0.43 |
|
| 2016 |
Nguyen L, Bohlen J, Stricker J, Chahal I, Zhang H, Pistilli EE. Hippocampus-specific deficiency of IL-15Rα contributes to greater anxiety-like behaviors in mice. Metabolic Brain Disease. PMID 27837366 DOI: 10.1007/S11011-016-9930-Y |
0.33 |
|
| 2016 |
Wang G, Chen L, Pan X, Chen J, Wang L, Wang W, Cheng R, Wu F, Feng X, Yu Y, Zhang HT, O'Donnell JM, Xu Y. The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling. Oncotarget. PMID 26980711 DOI: 10.18632/Oncotarget.8041 |
0.464 |
|
| 2016 |
Xu Y, Chen Z, Pan J, Zhang H, O’Donnell JM. Memory enhancement induced by PDE2 knockdown in an Alzheimer’s disease model of mice The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.707.6 |
0.399 |
|
| 2015 |
Wang ZZ, Yang WX, Zhang Y, Zhao N, Zhang YZ, Liu YQ, Xu Y, Wilson SP, O'Donnell JM, Zhang HT, Li YF. Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice. Scientific Reports. 5: 11332. PMID 26161529 DOI: 10.1038/Srep11332 |
0.445 |
|
| 2015 |
Pang C, Cao L, Wu F, Wang L, Wang G, Yu Y, Zhang M, Chen L, Wang W, Chen L, Zhu J, Pan J, Zhang H, Xu Y, Ding L. The effect of trans-resveratrol on post-stroke depression via regulation of hypothalamus-pituitary-adrenal axis. Neuropharmacology. PMID 25937213 DOI: 10.1016/J.Neuropharm.2015.04.017 |
0.348 |
|
| 2015 |
Xu Y, Pan J, Sun J, Ding L, Ruan L, Reed M, Yu X, Klabnik J, Lin D, Li J, Chen L, Zhang C, Zhang H, O'Donnell JM. Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress. Neurobiology of Aging. 36: 955-70. PMID 25442113 DOI: 10.1016/J.Neurobiolaging.2014.08.028 |
0.425 |
|
| 2015 |
Hansen RT, Zhang HT. Phosphodiesterase-4 modulation as a potential therapeutic for cognitive loss in pathological and non-pathological aging: possibilities and pitfalls. Current Pharmaceutical Design. 21: 291-302. PMID 25159075 DOI: 10.2174/1381612820666140826114208 |
0.749 |
|
| 2015 |
Zhang C, Yu Y, Ruan L, Wang C, Pan J, Klabnik J, Lueptow L, Zhang HT, O'Donnell JM, Xu Y. The roles of phosphodiesterase 2 in the central nervous and peripheral systems. Current Pharmaceutical Design. 21: 274-90. PMID 25159070 DOI: 10.2174/1381612820666140826115245 |
0.437 |
|
| 2015 |
Wang ZZ, Zhang Y, Zhang HT, Li YF. Phosphodiesterase: an interface connecting cognitive deficits to neuropsychiatric and neurodegenerative diseases. Current Pharmaceutical Design. 21: 303-16. PMID 25159069 DOI: 10.2174/1381612820666140826115559 |
0.428 |
|
| 2014 |
Lai M, Zhu H, Sun A, Zhuang D, Fu D, Chen W, Zhang HT, Zhou W. The phosphodiesterase-4 inhibitor rolipram attenuates heroin-seeking behavior induced by cues or heroin priming in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1397-407. PMID 24832929 DOI: 10.1017/S1461145714000595 |
0.365 |
|
| 2014 |
Wang C, Zhang J, Lu Y, Lin P, Pan T, Zhao X, Liu A, Wang Q, Zhou W, Zhang HT. Antidepressant-like effects of the phosphodiesterase-4 inhibitor etazolate and phosphodiesterase-5 inhibitor sildenafil via cyclic AMP or cyclic GMP signaling in mice. Metabolic Brain Disease. 29: 673-82. PMID 24705918 DOI: 10.1007/S11011-014-9533-4 |
0.422 |
|
| 2014 |
Ding L, Zhang C, Masood A, Li J, Sun J, Nadeem A, Zhang HT, O'Donnell JM, Xu Y. Protective effects of phosphodiesterase 2 inhibitor on depression- and anxiety-like behaviors: involvement of antioxidant and anti-apoptotic mechanisms. Behavioural Brain Research. 268: 150-8. PMID 24694839 DOI: 10.1016/J.Bbr.2014.03.042 |
0.401 |
|
| 2014 |
Hansen RT, Conti M, Zhang HT. Mice deficient in phosphodiesterase-4A display anxiogenic-like behavior. Psychopharmacology. 231: 2941-54. PMID 24563185 DOI: 10.1007/S00213-014-3480-Y |
0.731 |
|
| 2014 |
Zhong P, Wang W, Pan B, Liu X, Zhang Z, Long JZ, Zhang HT, Cravatt BF, Liu QS. Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1763-76. PMID 24476943 DOI: 10.1038/Npp.2014.24 |
0.363 |
|
| 2014 |
Zhang C, Cheng Y, Wang H, Wang C, Wilson SP, Xu J, Zhang HT. RNA interference-mediated knockdown of long-form phosphodiesterase-4D (PDE4D) enzyme reverses amyloid-β42-induced memory deficits in mice. Journal of Alzheimer's Disease : Jad. 38: 269-80. PMID 23948935 DOI: 10.3233/Jad-122236 |
0.38 |
|
| 2013 |
Richter W, Menniti FS, Zhang HT, Conti M. PDE4 as a target for cognition enhancement. Expert Opinion On Therapeutic Targets. 17: 1011-27. PMID 23883342 DOI: 10.1517/14728222.2013.818656 |
0.432 |
|
| 2013 |
Hansen RT, Zhang HT. Senescent-induced dysregulation of cAMP/CREB signaling and correlations with cognitive decline. Brain Research. 1516: 93-109. PMID 23623816 DOI: 10.1016/J.Brainres.2013.04.033 |
0.731 |
|
| 2013 |
Wang ZZ, Zhang Y, Liu YQ, Zhao N, Zhang YZ, Yuan L, An L, Li J, Wang XY, Qin JJ, Wilson SP, O'Donnell JM, Zhang HT, Li YF. RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects. British Journal of Pharmacology. 168: 1001-14. PMID 23003922 DOI: 10.1111/J.1476-5381.2012.02225.X |
0.468 |
|
| 2013 |
Tang SS, Wang XY, Hong H, Long Y, Li YQ, Xiang GQ, Jiang LY, Zhang HT, Liu LP, Miao MX, Hu M, Zhang TT, Hu W, Ji H, Ye FY. Leukotriene D4 induces cognitive impairment through enhancement of CysLT₁ R-mediated amyloid-β generation in mice. Neuropharmacology. 65: 182-92. PMID 22982445 DOI: 10.1016/J.Neuropharm.2012.08.026 |
0.371 |
|
| 2013 |
Seminerio MJ, Hansen R, Kaushal N, Zhang HT, McCurdy CR, Matsumoto RR. The evaluation of AZ66, an optimized sigma receptor antagonist, against methamphetamine-induced dopaminergic neurotoxicity and memory impairment in mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1033-44. PMID 22932447 DOI: 10.1017/S1461145712000831 |
0.707 |
|
| 2013 |
Xu Y, Pan J, Chen L, Zhang C, Sun J, Li J, Nguyen L, Nair N, Zhang H, O'Donnell JM. Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 835-47. PMID 22850435 DOI: 10.1017/S146114571200065X |
0.38 |
|
| 2012 |
Bin J, Wang Q, Zhuo YY, Xu JP, Zhang HT. Piperphentonamine (PPTA) attenuated cerebral ischemia-induced memory deficits via neuroprotection associated with anti-apoptotic activity. Metabolic Brain Disease. 27: 495-505. PMID 22843383 DOI: 10.1007/S11011-012-9330-X |
0.351 |
|
| 2012 |
Wen RT, Zhang M, Qin WJ, Liu Q, Wang WP, Lawrence AJ, Zhang HT, Liang JH. The phosphodiesterase-4 (PDE4) inhibitor rolipram decreases ethanol seeking and consumption in alcohol-preferring Fawn-Hooded rats. Alcoholism, Clinical and Experimental Research. 36: 2157-67. PMID 22671516 DOI: 10.1111/J.1530-0277.2012.01845.X |
0.351 |
|
| 2012 |
Wang C, Yang XM, Zhuo YY, Zhou H, Lin HB, Cheng YF, Xu JP, Zhang HT. The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 749-66. PMID 21733236 DOI: 10.1017/S1461145711000836 |
0.437 |
|
| 2011 |
Xu Y, Zhang HT, O'Donnell JM. Phosphodiesterases in the central nervous system: implications in mood and cognitive disorders. Handbook of Experimental Pharmacology. 447-85. PMID 21695652 DOI: 10.1007/978-3-642-17969-3_19 |
0.442 |
|
| 2011 |
Hu W, Lu T, Chen A, Huang Y, Hansen R, Chandler LJ, Zhang HT. Inhibition of phosphodiesterase-4 decreases ethanol intake in mice. Psychopharmacology. 218: 331-9. PMID 21509503 DOI: 10.1007/S00213-011-2290-8 |
0.691 |
|
| 2011 |
Li LX, Cheng YF, Lin HB, Wang C, Xu JP, Zhang HT. Prevention of cerebral ischemia-induced memory deficits by inhibition of phosphodiesterase-4 in rats. Metabolic Brain Disease. 26: 37-47. PMID 21327879 DOI: 10.1007/S11011-011-9235-0 |
0.372 |
|
| 2011 |
Li YF, Cheng YF, Huang Y, Conti M, Wilson SP, O'Donnell JM, Zhang HT. Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 172-83. PMID 21209202 DOI: 10.1523/Jneurosci.5236-10.2011 |
0.442 |
|
| 2010 |
Cheng YF, Wang C, Lin HB, Li YF, Huang Y, Xu JP, Zhang HT. Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats. Psychopharmacology. 212: 181-91. PMID 20640406 DOI: 10.1007/S00213-010-1943-3 |
0.434 |
|
| 2009 |
Li YF, Huang Y, Amsdell SL, Xiao L, O'Donnell JM, Zhang HT. Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2404-19. PMID 19516250 DOI: 10.1038/Npp.2009.66 |
0.378 |
|
| 2009 |
Zhang HT. Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs. Current Pharmaceutical Design. 15: 1688-98. PMID 19442182 DOI: 10.2174/138161209788168092 |
0.414 |
|
| 2009 |
Lin HB, Yang XM, Li TJ, Cheng YF, Zhang HT, Xu JP. Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer's disease. Psychopharmacology. 204: 705-14. PMID 19263040 DOI: 10.1007/S00213-009-1499-2 |
0.337 |
|
| 2009 |
Cashman JR, Voelker T, Zhang HT, O'Donnell JM. Dual inhibitors of phosphodiesterase-4 and serotonin reuptake. Journal of Medicinal Chemistry. 52: 1530-9. PMID 19256502 DOI: 10.1021/Jm8010993 |
0.304 |
|
| 2009 |
Zhao Z, Zhang HT, Bootzin E, Millan MJ, O'Donnell JM. Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1467-81. PMID 18923402 DOI: 10.1038/Npp.2008.183 |
0.335 |
|
| 2008 |
Zhang HT, Huang Y, Masood A, Stolinski LR, Li Y, Zhang L, Dlaboga D, Jin SL, Conti M, O'Donnell JM. Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1611-23. PMID 17700644 DOI: 10.1038/Sj.Npp.1301537 |
0.379 |
|
| 2006 |
Zhang HT, Zhao Y, Huang Y, Deng C, Hopper AT, De Vivo M, Rose GM, O'Donnell JM. Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats. Psychopharmacology. 186: 209-17. PMID 16586089 DOI: 10.1007/S00213-006-0369-4 |
0.324 |
|
| 2003 |
Zhao Y, Zhang HT, O'Donnell JM. Antidepressant-induced increase in high-affinity rolipram binding sites in rat brain: dependence on noradrenergic and serotonergic function. The Journal of Pharmacology and Experimental Therapeutics. 307: 246-53. PMID 12954819 DOI: 10.1124/Jpet.103.053215 |
0.302 |
|
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