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Yanwen Jiang, Ph.D. - Publications

Affiliations: 
2007 University of Chicago, Chicago, IL 
Area:
Molecular Biology, Genetics
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Doane AS, Chu CS, Di Giammartino DC, Rivas MA, Hellmuth JC, Jiang Y, Yusufova N, Alonso A, Roeder RG, Apostolou E, Melnick AM, Elemento O. OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity. Nature Immunology. PMID 34556886 DOI: 10.1038/s41590-021-01025-w  0.323
2020 Venturutti L, Teater M, Zhai A, Chadburn A, Babiker L, Kim D, Béguelin W, Lee TC, Kim Y, Chin CR, Yewdell WT, Raught B, Phillip JM, Jiang Y, Staudt LM, et al. TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell. PMID 32619424 DOI: 10.1016/J.Cell.2020.05.049  0.411
2019 Pastore A, Gaiti F, Lu SX, Brand RM, Kulm S, Chaligne R, Gu H, Huang KY, Stamenova EK, Béguelin W, Jiang Y, Schulman RC, Kim KT, Alonso A, Allan JN, et al. Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nature Communications. 10: 1874. PMID 31015400 DOI: 10.1038/S41467-019-09645-5  0.432
2019 Agirre X, Meydan C, Jiang Y, Garate L, Doane AS, Li Z, Verma A, Paiva B, Martín-Subero JI, Elemento O, Mason CE, Prosper F, Melnick A. Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response. Nature Communications. 10: 821. PMID 30778059 DOI: 10.1038/S41467-019-08679-Z  0.353
2017 Oricchio E, Katanayeva N, Donaldson MC, Sungalee S, Joyce PP, Béguelin W, Battistello E, Sanghvi VR, Jiang M, Jiang Y, Teater M, Parmigiani A, Budanov AV, Chan FC, Shah SP, et al. Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma. Science Translational Medicine. 9. PMID 28659443 DOI: 10.1126/Scitranslmed.Aak9969  0.393
2017 Valls E, Lobry C, Geng H, Wang L, Cardenas M, Rivas M, Cerchietti L, Oh P, Yang SN, Oswald E, Graham CW, Jiang Y, Hatzi K, Agirre X, Perkey E, et al. BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells. Cancer Discovery. PMID 28232365 DOI: 10.1158/2159-8290.Cd-16-1189  0.396
2017 Fachel AA, Jiang Y, Tam W, Muley AS, Meydan C, Agirre X, Melnick AM, Richards KL. Abstract 30: SOX9 enhancer regulator may play an oncogenic role in B-cell lymphomas Clinical Cancer Research. 23: 30-30. DOI: 10.1158/1557-3265.Hemmal17-30  0.465
2016 Jiang Y, Ortega-Molina A, Geng H, Ying HY, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre Ena X, Teater M, Meydan C, Li Z, Poloway D, Wang S, et al. CREBBP Inactivation Promotes the Development of HDAC3 Dependent Lymphomas. Cancer Discovery. PMID 27733359 DOI: 10.1158/2159-8290.Cd-16-0975  0.389
2016 Bunting KL, Soong TD, Singh R, Jiang Y, Béguelin W, Poloway DW, Swed BL, Hatzi K, Reisacher W, Teater M, Elemento O, Melnick AM. Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region. Immunity. PMID 27637145 DOI: 10.1016/J.Immuni.2016.08.012  0.472
2016 Jiang Y, Dominguez PM, Melnick A. The many layers of epigenetic dysfunction in B-cell lymphomas. Current Opinion in Hematology. PMID 27055146 DOI: 10.1097/Moh.0000000000000249  0.334
2016 Ying H, Jiang Y, Ortega-Molina A, Geng H, McNally D, Wang L, Doane A, Agirre X, Ju H, Poloway D, Teater M, Parsa S, Ennishi D, Scott DW, Shaknovich R, et al. Crebbp Mutations Disrupt Dynamic Enhancer Acetylation in B-Cells, Enabling HDAC3 to Drive Lymphomagenesis Blood. 128: 735-735. DOI: 10.1182/Blood.V128.22.735.735  0.439
2016 Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Lee J, Chen H, Ennishi D, Scott DW, Hother C, Liu S, Cao X, et al. Abstract IA18: Functional characterization of the tumor suppressor lysine-specific methyltransferase KMT2D in lymphoma Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-Ia18  0.312
2015 Jiang Y, Nie K, Redmond D, Melnick AM, Tam W, Elemento O. VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma. Journal of Visualized Experiments : Jove. PMID 26780364 DOI: 10.3791/53215  0.355
2015 Verma A, Jiang Y, Du W, Fairchild L, Melnick A, Elemento O. Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma. Genome Medicine. 7: 110. PMID 26521025 DOI: 10.1182/Blood.V126.23.2427.2427  0.425
2015 Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, et al. The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nature Medicine. PMID 26366710 DOI: 10.1038/Nm.3943  0.435
2015 Pan H, Jiang Y, Boi M, Tabbò F, Redmond D, Nie K, Ladetto M, Chiappella A, Cerchietti L, Shaknovich R, Melnick AM, Inghirami GG, Tam W, Elemento O. Epigenomic evolution in diffuse large B-cell lymphomas. Nature Communications. 6: 6921. PMID 25891015 DOI: 10.1182/Blood.V122.21.634.634  0.384
2015 Shih AH, Jiang Y, Meydan C, Shank K, Pandey S, Barreyro L, Antony-Debre I, Viale A, Socci N, Sun Y, Robertson A, Cavatore M, de Stanchina E, Hricik T, Rapaport F, et al. Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia. Cancer Cell. 27: 502-15. PMID 25873173 DOI: 10.1016/J.Ccell.2015.03.009  0.384
2015 Jiang Y, Melnick A. The epigenetic basis of diffuse large B-cell lymphoma. Seminars in Hematology. 52: 86-96. PMID 25805588 DOI: 10.1053/J.Seminhematol.2015.01.003  0.426
2015 Geyer JT, Subramaniyam S, Jiang Y, Elemento O, Ferry JA, de Leval L, Nakashima MO, Liu YC, Martin P, Mathew S, Orazi A, Tam W. Lymphoblastic transformation of follicular lymphoma: a clinicopathologic and molecular analysis of 7 patients. Human Pathology. 46: 260-71. PMID 25529125 DOI: 10.1016/J.Humpath.2014.10.021  0.323
2015 Hou Y, Wang X, Li L, Fan R, Chen J, Zhu T, Li W, Jiang Y, Mittal N, Wu W, Peace D, Qian Z. FHL2 regulates hematopoietic stem cell functions under stress conditions. Leukemia. 29: 615-24. PMID 25179730 DOI: 10.1038/Leu.2014.254  0.367
2015 Ortega-Molina A, Boss I, Pan H, Jiang Y, Hu D, Gao X, Shaknovich R, Shilatifard A, Melnick AM, Wendel H. Abstract LB-064: Characterization of the tumor suppressor function of the lysine-specific methyltransferase KMT2D in follicular lymphoma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-064  0.421
2014 Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC, Hua Y, Bulic M, Jiang Y, Carrara M, Calogero RA, et al. Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation. Plos Genetics. 10: e1004566. PMID 25188243 DOI: 10.1371/Journal.Pgen.1004566  0.392
2014 Jiang Y, Elemento O. Tracing the roots of cancer evolution. Cancer Discovery. 4: 995-7. PMID 25185189 DOI: 10.1158/2159-8290.Cd-14-0743  0.391
2014 Huang C, Gonzalez DG, Cote CM, Jiang Y, Hatzi K, Teater M, Dai K, Hla T, Haberman AM, Melnick A. The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers. Cell Reports. 8: 1497-508. PMID 25176650 DOI: 10.1016/J.Celrep.2014.07.059  0.362
2014 Jiang Y, Redmond D, Nie K, Eng KW, Clozel T, Martin P, Tan LH, Melnick AM, Tam W, Elemento O. Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas. Genome Biology. 15: 432. PMID 25123191 DOI: 10.1186/s13059-014-0432-0  0.385
2014 Du W, Goldstein R, Jiang Y, Aly O, Cerchietti L, Melnick AM, Elemento O. A Virtual B Cell Lymphoma Model to Predict Effective Combination Therapy Blood. 124: 928-928. DOI: 10.1182/Blood.V124.21.928.928  0.311
2014 Beguelin W, Teater M, Popovic R, Jiang Y, Cerchietti L, Shaknovich R, Gascoyne R, Levine R, Abdel-Wahab O, Licht J, Elemento O, Melnick AM. Abstract SY09-03: How deregulation of histone methyltransferases drive malignant transformation of B-cells Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy09-03  0.499
2014 Beguelin W, Sawh S, Chambwe N, Geng H, Jiang Y, Dominguez PM, Tam W, Shaknovich R. Abstract LB-235: IL10 autoregulatory loop in DLBCLs: New biomarker and a therapeutic target Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-235  0.364
2013 Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD, Xue F, Mason CE, Hiebert SW, et al. A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters. Cell Reports. 4: 578-88. PMID 23911289 DOI: 10.1016/J.Celrep.2013.06.016  0.427
2013 Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature. 500: 93-7. PMID 23812588 DOI: 10.1038/Nature12287  0.377
2013 Jiang Y, Hatzi K, Shaknovich R. Mechanisms of epigenetic deregulation in lymphoid neoplasms. Blood. 121: 4271-9. PMID 23704048 DOI: 10.1182/Blood-2012-12-451799  0.416
2013 Béguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SN, Wang L, Ezponda T, Martinez-Garcia E, Zhang H, Zheng Y, Verma SK, McCabe MT, et al. EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell. 23: 677-92. PMID 23680150 DOI: 10.1016/J.Ccr.2013.04.011  0.428
2013 Lu Z, Tsai AG, Akasaka T, Ohno H, Jiang Y, Melnick AM, Greisman HA, Lieber MR. BCL6 breaks occur at different AID sequence motifs in Ig-BCL6 and non-Ig-BCL6 rearrangements. Blood. 121: 4551-4. PMID 23476051 DOI: 10.1182/Blood-2012-10-464958  0.413
2013 De S, Shaknovich R, Riester M, Elemento O, Geng H, Kormaksson M, Jiang Y, Woolcock B, Johnson N, Polo JM, Cerchietti L, Gascoyne RD, Melnick A, Michor F. Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity. Plos Genetics. 9: e1003137. PMID 23326238 DOI: 10.1371/Journal.Pgen.1003137  0.505
2013 Popovic R, Martinez-Garcia E, Zhang Q, Ezponda T, Shah MY, Zhang Y, Jiang Y, Will CM, Small EC, Bulic M, Elemento O, Kelleher N, Kath W, Wang J, Licht JD. MMSET dysregulates gene expression in myeloma through global and focal changes in H3K36 and H3K27 methylation Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P66  0.432
2013 Shih AH, Jiang Y, Shank K, Pandey S, Viale A, Sun Y, Socci N, Robertson A, de Stanchina E, Hricik T, Rapaport F, Woods B, Cimmino L, Barreyro L, Steidl U, et al. Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML Blood. 122: 476-476. DOI: 10.1182/Blood.V122.21.476.476  0.4
2013 Teater MR, Hatzi K, Popovich R, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SN, Chung YR, Shaknovich R, Creasy C, Gascoyne RD, Cerchietti L, Levine RL, Abdel-Wahab O, et al. EZH2 and BCL6 Cooperate To Create The Germinal Center B-Cell Phenotype and Induce Lymphomas Through Formation and Repression Of Bivalent Chromatin Domains Blood. 122: 1-1. DOI: 10.1182/Blood.V122.21.1.1  0.456
2013 Chatzi K, Jiang Y, Huang C, Zumbo P, Bhaskara S, MacKerell AD, Xue F, Mason CE, Hiebert SW, Cerchietti L, Bardwell VJ, Elemento O, Ari M. Abstract B14: A biochemical basis for toggling enhancers from the active to poised state in B-cells Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B14  0.449
2013 Sun X, Wang Z, Wang L, Jiang Y, Soong TD, Kost N, Chen W, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. Abstract LB-111: A stable transcription factor complex nucleated by dimeric AML1-ETO controls leukemogenesis. Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2013-Lb-111  0.366
2013 Jiang Y, Redmond D, Nie K, Martin P, Melnick A, Tam W, Elemento O. Abstract 3183: Deep-sequencing reveals distinct clonal evolution patterns of DLBCL relapse and identifies mutant MLL2 as potential early driver. Cancer Research. 73: 3183-3183. DOI: 10.1158/1538-7445.Am2013-3183  0.327
2012 Jiang Y, Soong TD, Wang L, Melnick AM, Elemento O. Genome-wide detection of genes targeted by Non-Ig somatic hypermutation in lymphoma Plos One. 7. PMID 22808135 DOI: 10.1371/Journal.Pone.0040332  0.461
2012 Jiang Y, Hatzi K, Elemento O, Melnick A. Enhancer Profiling Reveals SOX9 As a Novel Transcription Regulator of B Cell Activation and DLBCL Transformation Blood. 120: 527-527. DOI: 10.1182/Blood.V120.21.527.527  0.469
2012 Popovic R, Martinez E, Zhang Q, Ezponda T, Jiang Y, Shah MY, Will C, Small EC, Elemento O, Wang J, Licht JD. MMSET Dysregulates Gene Expression in Myeloma Through Global and Focal Changes in H3K36 and H3K27 Methylation Blood. 120: 523-523. DOI: 10.1182/Blood.V120.21.523.523  0.443
2012 Bunting KL, Soong D, Jiang Y, Swed BL, Hatzi K, Shaknovich R, Reisacher W, Elemento O, Melnick A. Three-Dimensional Reorganization of the Genome During B Cell Affinity Maturation Blood. 120: 279-279. DOI: 10.1182/Blood.V120.21.279.279  0.478
2011 Wang L, Gural A, Sun XJ, Zhao X, Perna F, Huang G, Hatlen MA, Vu L, Liu F, Xu H, Asai T, Xu H, Deblasio T, Menendez S, Voza F, ... Jiang Y, et al. The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (New York, N.Y.). 333: 765-9. PMID 21764752 DOI: 10.1126/Science.1201662  0.362
2011 Bunting KL, Soong TD, Chatzi K, Jiang Y, Elemento O, Melnick A. A Role for BCL6 in the Higher-Order Organization of Genes in DLBCL Blood. 118: 558-558. DOI: 10.1182/Blood.V118.21.558.558  0.517
2011 Jiang Y, Soong D, Huang C, Monni S, Melnick A, Elemento O. Genomewide Detection of Genes Targeted by Aberrant Somatic Hypermutation in Lymphoma Blood. 118: 3474-3474. DOI: 10.1182/Blood.V118.21.3474.3474  0.48
2010 Palakodeti A, Lucas I, Jiang Y, Young DJ, Fernald AA, Karrison T, Le Beau MM. Impaired replication dynamics at the FRA3B common fragile site. Human Molecular Genetics. 19: 99-110. PMID 19815620 DOI: 10.1093/Hmg/Ddp470  0.696
2009 Jiang Y, Lucas I, Young DJ, Davis EM, Karrison T, Rest JS, Le Beau MM. Common fragile sites are characterized by histone hypoacetylation. Human Molecular Genetics. 18: 4501-12. PMID 19717471 DOI: 10.1093/Hmg/Ddp410  0.587
2009 Qian Z, Mao L, Fernald AA, Yu H, Luo R, Jiang Y, Anastasi J, Valk PJ, Delwel R, Le Beau MM. Enhanced expression of FHL2 leads to abnormal myelopoiesis in vivo. Leukemia. 23: 1650-7. PMID 19369964 DOI: 10.1038/Leu.2009.78  0.388
2007 Lucas I, Palakodeti A, Jiang Y, Young DJ, Jiang N, Fernald AA, Le Beau MM. High-throughput mapping of origins of replication in human cells. Embo Reports. 8: 770-7. PMID 17668008 DOI: 10.1038/Sj.Embor.7401026  0.695
2004 Palakodeti A, Han Y, Jiang Y, Le Beau MM. The role of late/slow replication of the FRA16D in common fragile site induction. Genes, Chromosomes & Cancer. 39: 71-6. PMID 14603443 DOI: 10.1002/Gcc.10290  0.691
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