Carolyn M. Klinge - Publications

Affiliations: 
University of Louisville, Louisville, KY, United States 
Area:
Biochemistry, Biomedical Engineering, Oncology

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Clark BJ, Klinge CM. Structure-function of DHEA binding proteins. Vitamins and Hormones. 123: 587-617. PMID 37717999 DOI: 10.1016/bs.vh.2022.12.002  0.341
2021 Petri BJ, Piell KM, South Whitt GC, Wilt AE, Poulton CC, Lehman NL, Clem BF, Nystoriak MA, Wysoczynski M, Klinge CM. HNRNPA2B1 regulates tamoxifen- and fulvestrant-sensitivity and hallmarks of endocrine resistance in breast cancer cells. Cancer Letters. 518: 152-168. PMID 34273466 DOI: 10.1016/j.canlet.2021.07.015  0.344
2020 Metcalf S, Petri BJ, Kruer T, Green B, Dougherty S, Wittliff JL, Klinge CM, Clem BF. Serine synthesis influences tamoxifen response in ER+ human breast carcinoma. Endocrine-Related Cancer. PMID 33112838 DOI: 10.1530/ERC-19-0510  0.354
2020 Petri BJ, Klinge CM. Regulation of breast cancer metastasis signaling by miRNAs. Cancer Metastasis Reviews. PMID 32577859 DOI: 10.1007/S10555-020-09905-7  0.371
2020 Klinge CM. Estrogenic control of mitochondrial function. Redox Biology. 101435. PMID 32001259 DOI: 10.1016/J.Redox.2020.101435  0.448
2020 Klinge CM, Piell KM, Clem BF, Petri BJ. OR09-06 HNRNPA2B1 Mediates Endocrine-Sensitivity and Alters PSAT1 in Breast Cancer Cells Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.651  0.436
2020 Metcalf S, Kruer T, Dougherty S, Wittliff JL, Klinge CM, Clem BF. Abstract 3734: Expression of serine synthetic enzymes alters the sensitivity of ER-positive breast cancer cells to tamoxifen Cancer Research. 80: 3734-3734. DOI: 10.1158/1538-7445.Am2020-3734  0.439
2019 Lakshmanan J, Zhang B, Wright K, Motameni AT, Jaganathan V, Schultz DJ, Klinge CM, Harbrecht BG. Tender coconut water suppresses hepatic inflammation by activating AKT and JNK signaling pathways in an model of sepsis. Journal of Functional Foods. 64. PMID 32863888 DOI: 10.1016/J.Jff.2019.103637  0.345
2019 Klinge CM, Piell KM, Tooley CS, Rouchka EC. HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells. Scientific Reports. 9: 9430. PMID 31263129 DOI: 10.1038/S41598-019-45636-8  0.313
2019 Wahlang B, Jin J, Hardesty JE, Head KZ, Shi H, Falkner KC, Prough RA, Klinge CM, Cave MC. Identifying sex differences arising from polychlorinated biphenyl exposures in toxicant-associated liver disease. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 31026535 DOI: 10.1016/J.Fct.2019.04.007  0.306
2019 Klinge C, Rouchka E. SUN-009 N(6)-Methyladenosine Reader HNRNPA2B1 Regulates Tamoxifen-Sensitivity in Breast Cancer Cells Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-009  0.381
2019 Metcalf S, Kruer T, Dougherty S, Biyik-Sit R, Klinge C, Clem B. Abstract 2845: The role of PSAT1 in triple negative breast cancer metastasis Cancer Research. 79: 2845-2845. DOI: 10.1158/1538-7445.Am2019-2845  0.361
2018 Klinge CM. Non-Coding RNAs in Breast Cancer: Intracellular and Intercellular Communication. Non-Coding Rna. 4. PMID 30545127 DOI: 10.3390/Ncrna4040040  0.378
2018 Clark BJ, Prough RA, Klinge CM. Mechanisms of Action of Dehydroepiandrosterone. Vitamins and Hormones. 108: 29-73. PMID 30029731 DOI: 10.1016/Bs.Vh.2018.02.003  0.472
2018 Klinge CM, Clark BJ, Prough RA. Dehydroepiandrosterone Research: Past, Current, and Future. Vitamins and Hormones. 108: 1-28. PMID 30029723 DOI: 10.1016/Bs.Vh.2018.02.002  0.347
2018 Carlisle SM, Trainor PJ, Doll MA, Stepp MW, Klinge CM, Hein DW. Knockout of Human Arylamine N-Acetyltransferase 1 (NAT1) in MDA-MB-231 Breast Cancer Cells Leads to Increased Reserve Capacity, Maximum Mitochondrial Capacity, and Glycolytic Reserve Capacity. Molecular Carcinogenesis. PMID 29964355 DOI: 10.1002/Mc.22869  0.425
2018 Schultz DJ, Krishna A, Vittitow SL, Alizadeh-Rad N, Muluhngwi P, Rouchka EC, Klinge CM. Transcriptomic response of breast cancer cells to anacardic acid. Scientific Reports. 8: 8063. PMID 29795261 DOI: 10.1038/S41598-018-26429-X  0.487
2018 Jones DZ, Schmidt ML, Suman S, Hobbing KR, Barve SS, Gobejishvili L, Brock G, Klinge CM, Rai SN, Park J, Clark GJ, Agarwal R, Kidd LR. Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells. Bmc Cancer. 18: 421. PMID 29653561 DOI: 10.1186/S12885-018-4258-0  0.314
2018 Klinge CM. Noncoding RNAs: long non-coding RNAs and microRNAs in endocrine-related cancers. Endocrine-Related Cancer. PMID 29440232 DOI: 10.1530/Erc-17-0548  0.306
2018 Zhang X, Carlisle SM, Doll MA, Martin RCG, States JC, Klinge CM, Hein DW. High N-acetyltransferase 1 (NAT1) expression is associated with estrogen receptor expression in breast tumors, but is not under direct regulation by estradiol, 17beta-diol, or dihydrotestosterone in breast cancer cells. The Journal of Pharmacology and Experimental Therapeutics. PMID 29339455 DOI: 10.1124/Jpet.117.247031  0.481
2018 Metcalf S, Kruer T, Klinge C, Clem B. Abstract P1-01-15: Investigation of phosphoserine aminotransferase 1 and its role in breast cancer progression Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P1-01-15  0.406
2017 Schultz DJ, Muluhngwi P, Alizadeh-Rad N, Green MA, Rouchka EC, Waigel SJ, Klinge CM. Genome-wide miRNA response to anacardic acid in breast cancer cells. Plos One. 12: e0184471. PMID 28886127 DOI: 10.1371/Journal.Pone.0184471  0.383
2017 Muluhngwi P, Alizadeh-Rad N, Vittitow SL, Kalbfleisch TS, Klinge CM. The miR-29 transcriptome in endocrine-sensitive and resistant breast cancer cells. Scientific Reports. 7: 5205. PMID 28701793 DOI: 10.1038/S41598-017-05727-W  0.343
2017 Klinge CM. Estrogens regulate life and death in mitochondria. Journal of Bioenergetics and Biomembranes. PMID 28401437 DOI: 10.1007/S10863-017-9704-1  0.472
2017 Muluhngwi P, Klinge CM. Identification of miRNAs as biomarkers for acquired endocrine resistance in breast cancer. Molecular and Cellular Endocrinology. PMID 28163101 DOI: 10.1016/J.Mce.2017.02.004  0.363
2017 Huff MO, Klinge CM. Regulation of Gene Expression by β-Glucans American Journal of Immunology. 13: 1-10. DOI: 10.3844/Ajisp.2017.1.10  0.37
2016 Muluhngwi P, Krishna A, Vittitow SL, Napier JT, Richardson KM, Ellis M, Mott JL, Klinge CM. Tamoxifen differentially regulates miR-29b-1 and miR-29a expression depending on endocrine-sensitivity in breast cancer cells. Cancer Letters. PMID 27986463 DOI: 10.1016/J.Canlet.2016.12.007  0.343
2016 Radde BN, Ivanova MM, Mai HX, Alizadeh-Rad N, Piell K, Van Hoose P, Cole MP, Muluhngwi P, Kalbfleisch TS, Rouchka EC, Hill BG, Klinge CM. Nuclear respiratory factor-1 and bioenergetics in tamoxifen-resistant breast cancer cells. Experimental Cell Research. PMID 27515002 DOI: 10.1016/J.Yexcr.2016.08.006  0.469
2016 Lan ZJ, Hu Y, Zhang S, Li X, Zhou H, Ding J, Klinge CM, Radde BN, Cooney AJ, Zhang J, Lei Z. GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells. Breast Cancer Research and Treatment. PMID 27357812 DOI: 10.1007/S10549-016-3880-2  0.514
2016 Huff MO, Todd SL, Smith AL, Elpers JT, Smith AP, Murphy RD, Bleser-Shartzer AS, Hoerter JE, Radde BN, Klinge CM. Arsenite and cadmium activate MAPK/ERK via membrane estrogen receptors and G-protein coupled estrogen receptor signaling in human lung adenocarcinoma cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27071941 DOI: 10.1093/Toxsci/Kfw064  0.485
2016 Radde BN, Alizadeh-Rad N, Price SM, Schultz DJ, Klinge CM. Anacardic Acid, Salicylic Acid, and Oleic Acid Differentially Alter Cellular Bioenergetic Function in Breast Cancer Cells. Journal of Cellular Biochemistry. PMID 26990649 DOI: 10.1002/Jcb.25544  0.393
2016 Prough R, Clark BJ, Klinge CM. Novel mechanisms for DHEA action. Journal of Molecular Endocrinology. PMID 26908835 DOI: 10.1530/Jme-16-0013  0.4
2016 Hu Y, Lan Z, Zhang S, Li X, Zhou H, Ding J, Klinge CM, Cooney AJ, Lei Z, Zhang J. GGNBP2 to suppress tumor growth through modulating ERα action in breast cancer. Journal of Clinical Oncology. 34: e12009-e12009. DOI: 10.1200/Jco.2016.34.15_Suppl.E12009  0.424
2015 Klinge CM. Estrogen action: Receptors, transcripts, cell signaling, and non-coding RNAs in normal physiology and disease. Molecular and Cellular Endocrinology. 418: 191-2. PMID 26681526 DOI: 10.1016/J.Mce.2015.11.028  0.373
2015 Muluhngwi P, Klinge CM. Roles for miRNAs in endocrine resistance in breast cancer. Endocrine-Related Cancer. 22: R279-300. PMID 26346768 DOI: 10.1530/Erc-15-0355  0.373
2015 Teng Y, Radde BN, Litchfield LM, Ivanova MM, Prough RA, Clark BJ, Doll MA, Hein DW, Klinge CM. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. The Journal of Biological Chemistry. 290: 15799-811. PMID 25969534 DOI: 10.1074/Jbc.M115.641167  0.375
2015 Bamji SF, Page RB, Patel D, Sanders A, Alvarez AR, Gambrell C, Naik K, Raghavan AM, Burow ME, Boue SM, Klinge CM, Ivanova M, Corbitt C. Soy glyceollins regulate transcript abundance in the female mouse brain. Functional & Integrative Genomics. PMID 25953511 DOI: 10.1007/S10142-015-0442-3  0.484
2015 Bonsignore LA, Butler JS, Klinge CM, Schaner Tooley CE. Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis. Oncotarget. 6: 12248-63. PMID 25909287 DOI: 10.18632/Oncotarget.3653  0.321
2015 Klinge CM. miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets. Molecular and Cellular Endocrinology. 418: 273-97. PMID 25659536 DOI: 10.1016/J.Mce.2015.01.035  0.376
2015 Radde BN, Ivanova MM, Mai HX, Salabei JK, Hill BG, Klinge CM. Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by oestradiol and tamoxifen. The Biochemical Journal. 465: 49-61. PMID 25279503 DOI: 10.1042/Bj20131608  0.45
2014 Teng Y, Litchfield LM, Ivanova MM, Prough RA, Clark BJ, Klinge CM. Dehydroepiandrosterone-induces miR-21 transcription in HepG2 cells through estrogen receptor β and androgen receptor. Molecular and Cellular Endocrinology. 392: 23-36. PMID 24845419 DOI: 10.1016/J.Mce.2014.05.007  0.343
2014 Jafaar ZM, Litchfield LM, Ivanova MM, Radde BN, Al-Rayyan N, Klinge CM. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. International Journal of Oncology. 44: 1365-75. PMID 24534923 DOI: 10.3892/Ijo.2014.2294  0.426
2014 Al-Rayyan N, Litchfield LM, Ivanova MM, Radde BN, Cheng A, Elbedewy A, Klinge CM. 5-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines. Cancer Letters. 347: 139-50. PMID 24513177 DOI: 10.1016/J.Canlet.2014.02.001  0.404
2014 Litchfield LM, Appana SN, Datta S, Klinge CM. COUP-TFII inhibits NFkappaB activation in endocrine-resistant breast cancer cells. Molecular and Cellular Endocrinology. 382: 358-67. PMID 24141032 DOI: 10.1016/J.Mce.2013.10.010  0.469
2014 Medjakovic S, Zoechling A, Gerster P, Ivanova MM, Teng Y, Klinge CM, Schildberger B, Gartner M, Jungbauer A. Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. Environmental Toxicology. 29: 1201-16. PMID 23436777 DOI: 10.1002/Tox.21852  0.48
2013 Ivanova MM, Radde BN, Son J, Mehta FF, Chung SH, Klinge CM. Estradiol and tamoxifen regulate NRF-1 and mitochondrial function in mouse mammary gland and uterus. Journal of Molecular Endocrinology. 51: 233-46. PMID 23892277 DOI: 10.1530/Jme-13-0051  0.474
2013 Manavalan TT, Teng Y, Litchfield LM, Muluhngwi P, Al-Rayyan N, Klinge CM. Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells. Plos One. 8: e62334. PMID 23626803 DOI: 10.1371/Journal.Pone.0062334  0.346
2013 Miller KK, Al-Rayyan N, Ivanova MM, Mattingly KA, Ripp SL, Klinge CM, Prough RA. DHEA metabolites activate estrogen receptors alpha and beta. Steroids. 78: 15-25. PMID 23123738 DOI: 10.1016/J.Steroids.2012.10.002  0.812
2013 Teng Y, Manavalan TT, Hu C, Medjakovic S, Jungbauer A, Klinge CM. Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 131: 71-83. PMID 23052036 DOI: 10.1093/Toxsci/Kfs290  0.378
2012 Jala VR, Radde BN, Haribabu B, Klinge CM. Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer. Bmc Cancer. 12: 624. PMID 23273253 DOI: 10.1186/1471-2407-12-624  0.455
2012 Litchfield LM, Klinge CM. Multiple roles of COUP-TFII in cancer initiation and progression. Journal of Molecular Endocrinology. 49: R135-48. PMID 22966133 DOI: 10.1530/Jme-12-0144  0.419
2012 Litchfield LM, Riggs KA, Hockenberry AM, Oliver LD, Barnhart KG, Cai J, Pierce WM, Ivanova MM, Bates PJ, Appana SN, Datta S, Kulesza P, McBryan J, Young LS, Klinge CM. Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells. Plos One. 7: e38278. PMID 22693611 DOI: 10.1371/Journal.Pone.0038278  0.438
2012 Klinge CM. Inhibition of non-small-cell lung cancer growth by combined fulvestrant and vandetanib. Future Oncology (London, England). 8: 529-33. PMID 22646768 DOI: 10.2217/Fon.12.42  0.378
2012 Klinge CM. miRNAs and estrogen action. Trends in Endocrinology and Metabolism: Tem. 23: 223-33. PMID 22503553 DOI: 10.1016/J.Tem.2012.03.002  0.36
2012 Hsu A, Zhang W, Lee JF, An J, Ekambaram P, Liu J, Honn KV, Klinge CM, Lee MJ. Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells. International Journal of Oncology. 40: 1619-26. PMID 22344462 DOI: 10.3892/Ijo.2012.1379  0.378
2012 Mattingly KA, Klinge CM. Diesel exhaust particulate extracts inhibit transcription of nuclear respiratory factor-1 and cell viability in human umbilical vein endothelial cells. Archives of Toxicology. 86: 633-42. PMID 22105178 DOI: 10.1007/S00204-011-0778-Y  0.801
2012 Litchfield LM, Klinge CM. Abstract 2214: COUP-TFII suppresses NFκB activation in endocrine-resistant breast cancer cells Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2012-2214  0.387
2012 Manavalan TT, Klinge CM. Abstract 1096: Loss of miR-200 family of microRNAs confers resistance to tamoxifen in human breast cancer cells Cancer Research. 72: 1096-1096. DOI: 10.1158/1538-7445.Am2012-1096  0.403
2012 Litchfield LM, Klinge CM. Abstract P6-04-30: COUP-TFII suppresses NFκB activation in endocrine-resistant breast cancer cells Cancer Research. 72: 2214-2214. DOI: 10.1158/0008-5472.Sabcs12-P6-04-30  0.478
2011 Manavalan TT, Teng Y, Appana SN, Datta S, Kalbfleisch TS, Li Y, Klinge CM. Differential expression of microRNA expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. Cancer Letters. 313: 26-43. PMID 21955614 DOI: 10.1016/J.Canlet.2011.08.018  0.373
2011 Klinge CM, Radde BN, Imbert-Fernandez Y, Teng Y, Ivanova MM, Abner SM, Martin AL. Targeting the intracellular MUC1 C-terminal domain inhibits proliferation and estrogen receptor transcriptional activity in lung adenocarcinoma cells. Molecular Cancer Therapeutics. 10: 2062-71. PMID 21862684 DOI: 10.1158/1535-7163.Mct-11-0381  0.475
2011 Imbert-Fernandez Y, Radde BN, Teng Y, Young WW, Hu C, Klinge CM. MUC1/A and MUC1/B splice variants differentially regulate inflammatory cytokine expression. Experimental Eye Research. 93: 649-57. PMID 21854773 DOI: 10.1016/J.Exer.2011.08.004  0.315
2011 Porter AM, Klinge CM, Gobin AS. Covalently grafted VEGF(165) in hydrogel models upregulates the cellular pathways associated with angiogenesis. American Journal of Physiology. Cell Physiology. 301: C1086-92. PMID 21795519 DOI: 10.1152/Ajpcell.00090.2011  0.301
2011 Ivanova MM, Luken KH, Zimmer AS, Lenzo FL, Smith RJ, Arteel MW, Kollenberg TJ, Mattingly KA, Klinge CM. Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor beta and AP-1 recruitment to adjacent promoter binding sites. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1402-16. PMID 21233487 DOI: 10.1096/Fj.10-169029  0.812
2011 Porter AM, Klinge CM, Gobin AS. Biomimetic hydrogels with VEGF induce angiogenic processes in both hUVEC and hMEC. Biomacromolecules. 12: 242-6. PMID 21128597 DOI: 10.1021/Bm101220B  0.305
2011 Ivanova MM, Abner SM, Pierce WM, Klinge CM. Ligand-dependent differences in estrogen receptor beta-interacting proteins identified in lung adenocarcinoma cells corresponds to estrogenic responses Proteome Science. 9. DOI: 10.1186/1477-5956-9-60  0.402
2011 Jala VR, Bodduluri H, Radde B, Klinge CM. Abstract 4548: The role of GPR30/G-protein coupled estrogen receptor (GPER) in lung cancer development Cancer Research. 71: 4548-4548. DOI: 10.1158/1538-7445.Am2011-4548  0.443
2010 Kumar A, Klinge CM, Goldstein RE. Estradiol-induced proliferation of papillary and follicular thyroid cancer cells is mediated by estrogen receptors alpha and beta. International Journal of Oncology. 36: 1067-80. PMID 20372779 DOI: 10.3892/Ijo_00000588  0.538
2010 Klinge CM, Riggs KA, Wickramasinghe NS, Emberts CG, McConda DB, Barry PN, Magnusen JE. Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription. Molecular and Cellular Endocrinology. 323: 268-76. PMID 20302909 DOI: 10.1016/J.Mce.2010.03.013  0.529
2010 Schultz DJ, Wickramasinghe NS, Ivanova MM, Isaacs SM, Dougherty SM, Imbert-Fernandez Y, Cunningham AR, Chen C, Klinge CM. Anacardic acid inhibits estrogen receptor alpha-DNA binding and reduces target gene transcription and breast cancer cell proliferation. Molecular Cancer Therapeutics. 9: 594-605. PMID 20197399 DOI: 10.1158/1535-7163.Mct-09-0978  0.563
2010 Ivanova MM, Mazhawidza W, Dougherty SM, Klinge CM. Sex differences in estrogen receptor subcellular location and activity in lung adenocarcinoma cells. American Journal of Respiratory Cell and Molecular Biology. 42: 320-30. PMID 19556604 DOI: 10.1165/Rcmb.2009-0059Oc  0.479
2009 Klinge CM. Estrogen Regulation of MicroRNA Expression. Current Genomics. 10: 169-83. PMID 19881910 DOI: 10.2174/138920209788185289  0.416
2009 Ivanova MM, Mazhawidza W, Dougherty SM, Minna JD, Klinge CM. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Molecular and Cellular Endocrinology. 305: 12-21. PMID 19433257 DOI: 10.1016/J.Mce.2009.01.021  0.561
2009 Sanada N, Gotoh Y, Shimazawa R, Klinge CM, Kizu R. Repression of activated aryl hydrocarbon receptor-induced transcriptional activation by 5alpha-dihydrotestosterone in human prostate cancer LNCaP and human breast cancer T47D cells. Journal of Pharmacological Sciences. 109: 380-7. PMID 19270430 DOI: 10.1254/Jphs.08328Fp  0.514
2009 Wickramasinghe NS, Manavalan TT, Dougherty SM, Riggs KA, Li Y, Klinge CM. Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells. Nucleic Acids Research. 37: 2584-95. PMID 19264808 DOI: 10.1093/Nar/Gkp117  0.405
2009 Wickramasinghe N, Manavalan T, Riggs K, Li Y, Klinge C. Estradiol downregulates miR-21 expression and miR-21 gene targets in MCF-7 breast cancer cells. Cancer Research. 69: 3051. DOI: 10.1158/0008-5472.Sabcs-3051  0.377
2008 Klinge CM. Estrogenic control of mitochondrial function and biogenesis. Journal of Cellular Biochemistry. 105: 1342-51. PMID 18846505 DOI: 10.1002/Jcb.21936  0.474
2008 Lu Z, Liu M, Stribinskis V, Klinge CM, Ramos KS, Colburn NH, Li Y. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene Oncogene. 27: 4373-4379. PMID 18372920 DOI: 10.1038/Onc.2008.72  0.319
2008 Klinge CM, Wickramasinghe NS, Ivanova MM, Dougherty SM. Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2185-97. PMID 18296501 DOI: 10.1096/Fj.07-103366  0.41
2008 Mattingly KA, Ivanova MM, Riggs KA, Wickramasinghe NS, Barch MJ, Klinge CM. Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis. Molecular Endocrinology (Baltimore, Md.). 22: 609-22. PMID 18048642 DOI: 10.1210/Me.2007-0029  0.805
2007 Sumanasekera WK, Ivanova MM, Johnston BJ, Dougherty SM, Sumanasekera GU, Myers SR, Ali Y, Kizu R, Klinge CM. Rapid effects of diesel exhaust particulate extracts on intracellular signaling in human endothelial cells. Toxicology Letters. 174: 61-73. PMID 17920790 DOI: 10.1016/J.Toxlet.2007.08.014  0.364
2007 Vijayanathan V, Greenfield NJ, Thomas TJ, Ivanova MM, Tyulmenkov VV, Klinge CM, Gallo MA, Thomas T. Effects of estradiol and 4-hydroxytamoxifen on the conformation, thermal stability, and DNA recognition of estrogen receptor beta. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 85: 1-10. PMID 17464340 DOI: 10.1139/o06-144  0.313
2007 Sumanasekera WK, Sumanasekera GU, Mattingly KA, Dougherty SM, Keynton RS, Klinge CM. Estradiol and dihydrotestosterone regulate endothelial cell barrier function after hypergravity-induced alterations in MAPK activity. American Journal of Physiology. Cell Physiology. 293: C566-73. PMID 17360813 DOI: 10.1152/Ajpcell.00418.2006  0.772
2007 Ivanova MM, Mattingly KA, Klinge CM. Estrogen receptor beta yield from baculovirus lytic infection is higher than from stably transformed Sf21 cells. Applied Microbiology and Biotechnology. 74: 1256-63. PMID 17318543 DOI: 10.1007/S00253-006-0784-9  0.779
2006 Riggs KA, Wickramasinghe NS, Cochrum RK, Watts MB, Klinge CM. Decreased chicken ovalbumin upstream promoter transcription factor II expression in tamoxifen-resistant breast cancer cells. Cancer Research. 66: 10188-98. PMID 17047084 DOI: 10.1158/0008-5472.Can-05-3937  0.515
2006 Dougherty SM, Mazhawidza W, Bohn AR, Robinson KA, Mattingly KA, Blankenship KA, Huff MO, McGregor WG, Klinge CM. Gender difference in the activity but not expression of estrogen receptors alpha and beta in human lung adenocarcinoma cells. Endocrine-Related Cancer. 13: 113-34. PMID 16601283 DOI: 10.1677/Erc.1.01118  0.791
2006 Sumanasekera WK, Zhao L, Ivanova M, Morgan DD, Noisin EL, Keynton RS, Klinge CM. Effect of estradiol and dihydrotestosterone on hypergravity-induced MAPK signaling and occludin expression in human umbilical vein endothelial cells. Cell and Tissue Research. 324: 243-53. PMID 16432714 DOI: 10.1007/S00441-005-0113-0  0.42
2005 Klinge CM, Blankenship KA, Risinger KE, Bhatnagar S, Noisin EL, Sumanasekera WK, Zhao L, Brey DM, Keynton RS. Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells. The Journal of Biological Chemistry. 280: 7460-8. PMID 15615701 DOI: 10.1074/Jbc.M411565200  0.507
2004 Klinge CM, Jernigan SC, Mattingly KA, Risinger KE, Zhang J. Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors alpha and beta by coactivators and corepressors. Journal of Molecular Endocrinology. 33: 387-410. PMID 15525597 DOI: 10.1677/Jme.1.01541  0.814
2004 Kizu R, Otsuki N, Kishida Y, Toriba A, Mizokami A, Burnstein KL, Klinge CM, Hayakawai K. A new luciferase reporter gene assay for the detection of androgenic and antiandrogenic effects based on a human prostate specific antigen promoter and PC3/AR human prostate cancer cells. Analytical Sciences : the International Journal of the Japan Society For Analytical Chemistry. 20: 55-9. PMID 14753257 DOI: 10.2116/Analsci.20.55  0.408
2004 Okamura K, Kizu R, Toriba A, Murahashi T, Mizokami A, Burnstein KL, Klinge CM, Hayakawa K. Antiandrogenic activity of extracts of diesel exhaust particles emitted from diesel-engine truck under different engine loads and speeds. Toxicology. 195: 243-54. PMID 14751679 DOI: 10.1016/J.Tox.2003.10.011  0.314
2004 Ramsey TL, Risinger KE, Jernigan SC, Mattingly KA, Klinge CM. Estrogen receptor beta isoforms exhibit differences in ligand-activated transcriptional activity in an estrogen response element sequence-dependent manner. Endocrinology. 145: 149-60. PMID 14500565 DOI: 10.1210/En.2003-1043  0.821
2004 Okamura K, Kizu R, Hayakawa K, Toriba A, Mizokami A, Burnstein KL, Klinge CM, Kato S. VARIATION IN THE ANTIANDROGENIC ACTIVITY OF DIESEL EXHAUST PARTICULATES EMITTED UNDER DIFFERENT ENGINE LOADS Polycyclic Aromatic Compounds. 24: 743-757. DOI: 10.1080/10406630490472518  0.314
2004 Khalyfa A, Klinge CM, Hall WC, Zhao X, Miller MM, Wang E. Erratum to “Transcription profiling of estrogen target genes in young and old mouse uterus” [Exp. Gerontol. 38 (2003) 1087–1099] Experimental Gerontology. 39: 455-457. DOI: 10.1016/J.Exger.2003.12.008  0.323
2003 Khalyfa A, Klinge CM, Hall WC, Zhao X, Miller MM, Wang E. Transcription profiling of estrogen target genes in young and old mouse uterus. Experimental Gerontology. 38: 1087-99. PMID 14580862 DOI: 10.1016/S0531-5565(03)00210-9  0.438
2003 Kizu R, Okamura K, Toriba A, Mizokami A, Burnstein KL, Klinge CM, Hayakawa K. Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 299-309. PMID 12970580 DOI: 10.1093/Toxsci/Kfg230  0.394
2003 Thomas PB, Risinger KE, Klinge CM. Identification of estrogen receptor beta expression in Chinese hamster ovary (CHO) cells and comparison of estrogen-responsive gene transcription in cells adapted to serum-free media. The Journal of Steroid Biochemistry and Molecular Biology. 86: 41-55. PMID 12943744 DOI: 10.1016/S0960-0760(03)00250-4  0.527
2003 Klinge CM, Risinger KE, Watts MB, Beck V, Eder R, Jungbauer A. Estrogenic activity in white and red wine extracts. Journal of Agricultural and Food Chemistry. 51: 1850-7. PMID 12643641 DOI: 10.1021/Jf0259821  0.491
2003 Kulakosky PC, Klinge CM. Maximizing production of estrogen receptor beta with the baculovirus expression system. Biotechniques. 34: 334-8, 340-3. PMID 12613256 DOI: 10.2144/03342Rr04  0.489
2002 Kulakosky PC, McCarty MA, Jernigan SC, Risinger KE, Klinge CM. Response element sequence modulates estrogen receptor alpha and beta affinity and activity. Journal of Molecular Endocrinology. 29: 137-52. PMID 12200235 DOI: 10.1677/Jme.0.0290137  0.55
2002 Klinge CM, Jernigan SC, Risinger KE. The agonist activity of tamoxifen is inhibited by the short heterodimer partner orphan nuclear receptor in human endometrial cancer cells. Endocrinology. 143: 853-67. PMID 11861507 DOI: 10.1210/Endo.143.3.8676  0.538
2002 Okamura K, Kizu R, Toriba A, Klinge CM, Hayakawa K. Antiestrogenic Activity of Extracts of Diesel Exhaust Particulate Matter in MCF-7 Human Breast Carcinoma Cells Polycyclic Aromatic Compounds. 22: 747-759. DOI: 10.1080/10406630290103906  0.463
2001 Lewis JS, Thomas TJ, Klinge CM, Gallo MA, Thomas T. Regulation of cell cycle and cyclins by 16α-hydroxyestrone in MCF-7 breast cancer cells Journal of Molecular Endocrinology. 27: 293-307. PMID 11719282 DOI: 10.1677/Jme.0.0270293  0.444
2001 Ramsey TL, Klinge CM. Estrogen response element binding induces alterations in estrogen receptor-alpha conformation as revealed by susceptibility to partial proteolysis. Journal of Molecular Endocrinology. 27: 275-92. PMID 11719281 DOI: 10.1677/Jme.0.0270275  0.525
2001 Tyulmenkov VV, Klinge CM. A mathematical approach to predict the affinity of estrogen receptors alpha and beta binding to DNA. Molecular and Cellular Endocrinology. 182: 109-19. PMID 11500244 DOI: 10.1016/S0303-7207(01)00508-1  0.497
2001 Klinge CM. Estrogen receptor interaction with estrogen response elements. Nucleic Acids Research. 29: 2905-19. PMID 11452016 DOI: 10.1093/Nar/29.14.2905  0.543
2001 Tyulmenkov VV, Klinge CM. Estrogen receptors alpha and beta exhibit different estradiol and estrogen response element binding in the presence of nonspecific DNA. Archives of Biochemistry and Biophysics. 390: 253-64. PMID 11396928 DOI: 10.1006/Abbi.2001.2382  0.47
2001 Klinge CM, Jernigan SC, Risinger KE, Lee JE, Tyulmenkov VV, Falkner KC, Prough RA. Short heterodimer partner (SHP) orphan nuclear receptor inhibits the transcriptional activity of aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT). Archives of Biochemistry and Biophysics. 390: 64-70. PMID 11368516 DOI: 10.1006/Abbi.2001.2366  0.468
2001 Shah N, Thomas TJ, Lewis JS, Klinge CM, Shirahata A, Gelinas C, Thomas T. Regulation of estrogenic and nuclear factor κB functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells Oncogene. 20: 1715-1729. PMID 11313919 DOI: 10.1038/Sj.Onc.1204247  0.508
2001 Klinge CM, Jernigan SC, Smith SL, Tyulmenkov VV, Kulakosky PC. Estrogen response element sequence impacts the conformation and transcriptional activity of estrogen receptor alpha. Molecular and Cellular Endocrinology. 174: 151-66. PMID 11306182 DOI: 10.1016/S0303-7207(01)00382-3  0.552
2000 Tyulmenkov VV, Klinge CM. Interaction of tetrahydrocrysene ketone with estrogen receptors alpha and beta indicates conformational differences in the receptor subtypes. Archives of Biochemistry and Biophysics. 381: 135-42. PMID 11019829 DOI: 10.1006/Abbi.2000.1974  0.447
2000 Bowers JL, Tyulmenkov VV, Jernigan SC, Klinge CM. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors α and β Endocrinology. 141: 3657-3667. PMID 11014220 DOI: 10.1210/Endo.141.10.7721  0.569
2000 Tyulmenkov VV, Klinge CM. Selectivity of antibodies to estrogen receptors alpha and beta (ERalpha and ERbeta) for detecting DNA-bound ERalpha and ERbeta in vitro. Steroids. 65: 505-12. PMID 10978729 DOI: 10.1016/S0039-128X(00)00109-4  0.403
2000 Tyulmenkov VV, Jernigan SC, Klinge CM. Comparison of transcriptional synergy of estrogen receptors alpha and beta from multiple tandem estrogen response elements. Molecular and Cellular Endocrinology. 165: 151-61. PMID 10940493 DOI: 10.1016/S0303-7207(00)00250-1  0.574
2000 Klinge CM. Estrogen receptor interaction with co-activators and co-repressors. Steroids. 65: 227-51. PMID 10751636 DOI: 10.1016/S0039-128X(99)00107-5  0.413
2000 Klinge CM, Kaur K, Swanson HI. The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1. Archives of Biochemistry and Biophysics. 373: 163-74. PMID 10620335 DOI: 10.1006/Abbi.1999.1552  0.529
2000 Klinge CM. Role of estrogen receptor ligand and estrogen response element sequence on interaction with chicken ovalbumin upstream promoter transcription factor (COUP-TF). The Journal of Steroid Biochemistry and Molecular Biology. 71: 1-19. PMID 10619353 DOI: 10.1016/S0960-0760(99)00124-7  0.559
1999 Klinge CM, Bowers JL, Kulakosky PC, Kamboj KK, Swanson HI. The aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT) heterodimer interacts with naturally occurring estrogen response elements. Molecular and Cellular Endocrinology. 157: 105-19. PMID 10619402 DOI: 10.1016/S0303-7207(99)00165-3  0.554
1999 Klinge CM. Estrogen receptor binding to estrogen response elements slows ligand dissociation and synergistically activates reporter gene expression. Molecular and Cellular Endocrinology. 150: 99-111. PMID 10411304 DOI: 10.1016/S0303-7207(99)00019-2  0.49
1999 Thomas T, Shah N, Klinge CM, Faaland CA, Adihkarakunnathu S, Gallo MA, Thomas TJ. Polyamine biosynthesis inhibitors alter protein-protein interactions involving estrogen receptor in MCF-7 breast cancer cells Journal of Molecular Endocrinology. 22: 131-139. PMID 10194516 DOI: 10.1677/Jme.0.0220131  0.506
1999 Klinge CM, Studinski-Jones AL, Kulakosky PC, Bambara RA, Hilf R. Comparison of tamoxifen ligands on estrogen receptor interaction with estrogen response elements. Molecular and Cellular Endocrinology. 143: 79-90. PMID 9806352 DOI: 10.1016/S0303-7207(98)00130-0  0.49
1998 Driscoll MD, Sathya G, Muyan M, Klinge CM, Hilf R, Bambara RA. Sequence requirements for estrogen receptor binding to estrogen response elements. The Journal of Biological Chemistry. 273: 29321-30. PMID 9792632 DOI: 10.1074/Jbc.273.45.29321  0.468
1997 Klinge CM, Brolly CL, Bambara RA, Hilf R. hsp70 is not required for high affinity binding of purified calf uterine estrogen receptor to estrogen response element DNA in vitro. The Journal of Steroid Biochemistry and Molecular Biology. 63: 283-301. PMID 9459195 DOI: 10.1016/S0960-0760(97)00091-5  0.476
1997 Sathya G, Li W, Klinge CM, Anolik JH, Hilf R, Bambara RA. Effects of multiple estrogen responsive elements, their spacing, and location on estrogen response of reporter genes. Molecular Endocrinology (Baltimore, Md.). 11: 1994-2003. PMID 9415403 DOI: 10.1210/Mend.11.13.0039  0.509
1997 Klinge CM, Silver BF, Driscoll MD, Sathya G, Bambara RA, Hilf R. Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression. The Journal of Biological Chemistry. 272: 31465-74. PMID 9395481 DOI: 10.1074/Jbc.272.50.31465  0.551
1997 Klinge CM, Bodenner DL, Desai D, Niles RM, Traish AM. Binding of type II nuclear receptors and estrogen receptor to full and half-site estrogen response elements in vitro Nucleic Acids Research. 25: 1903-1912. PMID 9115356 DOI: 10.1093/Nar/25.10.1903  0.491
1996 Anolik JH, Klinge CM, Brolly CL, Bambara RA, Hilf R. Stability of the ligand-estrogen receptor interaction depends on estrogen response element flanking sequences and cellular factors. The Journal of Steroid Biochemistry and Molecular Biology. 59: 413-29. PMID 9010347 DOI: 10.1016/S0960-0760(96)00129-X  0.484
1996 Driscoll MD, Klinge CM, Hilf R, Bambara RA. Footprint analysis of estrogen receptor binding to adjacent estrogen response elements. The Journal of Steroid Biochemistry and Molecular Biology. 58: 45-61. PMID 8809185 DOI: 10.1016/0960-0760(96)00015-5  0.489
1996 Klinge CM, Traish AM, Driscoll MD, Hilf R, Bambara RA. Site-directed estrogen receptor antibodies stabilize 4-hydroxytamoxifen ligand, but not estradiol, and indicate ligand-specific differences in the recognition of estrogen response element DNA in vitro. Steroids. 61: 278-89. PMID 8738832 DOI: 10.1016/0039-128X(95)00219-G  0.492
1996 Tzeng DZ, Klinge CM. Phosphorylation of purified estradiol-liganded estrogen receptor by casein kinase II increases estrogen response element binding but does not alter ligand stability. Biochemical and Biophysical Research Communications. 223: 554-60. PMID 8687434 DOI: 10.1006/Bbrc.1996.0933  0.417
1996 Klinge CM, Traish AM, Bambara RA, Hilf R. Dissociation of 4-hydroxytamoxifen, but not estradiol or tamoxifen aziridine, from the estrogen receptor as the receptor binds estrogen response element DNA Journal of Steroid Biochemistry and Molecular Biology. 57: 51-66. PMID 8645617 DOI: 10.1016/0960-0760(95)00246-4  0.483
1995 Anolik JH, Klinge CM, Hilf R, Bambara RA. Cooperative binding of estrogen receptor to DNA depends on spacing of binding sites, flanking sequence, and ligand. Biochemistry. 34: 2511-20. PMID 7873531 DOI: 10.1021/Bi00008A015  0.474
1995 Thomas T, Gallo MA, Klinge CM, Thomas TJ. Polyamine-mediated conformational perturbations in DNA alter the binding of estrogen receptor to poly(dG-m5dC).poly(dG-m5dC) and a plasmid containing the estrogen response element Journal of Steroid Biochemistry and Molecular Biology. 54: 89-99. PMID 7662593 DOI: 10.1016/0960-0760(95)00126-K  0.45
1995 Traish AM, Al-Fadhli S, Klinge C, Kounine M, Quick TC. Identification of structurally altered estrogen receptors in human breast cancer by site-directed monoclonal antibodies Steroids. 60: 467-474. PMID 7482632 DOI: 10.1016/0039-128X(95)00061-T  0.401
1994 Anolik JH, Klinge CM, Bambara RA, Hilf R. Differential impact of flanking sequences on estradiol- vs 4-hydroxytamoxifen-liganded estrogen receptor binding to estrogen responsive element DNA. The Journal of Steroid Biochemistry and Molecular Biology. 46: 713-30. PMID 8274405 DOI: 10.1016/0960-0760(93)90312-K  0.492
1992 Klinge CM, Bambara RA, Hilf R. Antiestrogen-liganded estrogen receptor interaction with estrogen responsive element DNA in vitro. The Journal of Steroid Biochemistry and Molecular Biology. 43: 249-62. PMID 1390277 DOI: 10.1016/0960-0760(92)90159-G  0.494
1991 Ludwig LB, Klinge CM, Peale FV, Bambara RA, Zain S, Hilf R. A microtiter well assay for quantitative measurement of estrogen receptor binding to estrogen-responsive elements. Molecular Endocrinology (Baltimore, Md.). 4: 1027-33. PMID 2284005 DOI: 10.1210/Mend-4-7-1027  0.425
1991 Ishibe Y, Klinge CM, Hilf R, Bambara RA. Estrogen receptor alters the topology of plasmid DNA containing estrogen responsive elements. Biochemical and Biophysical Research Communications. 176: 486-91. PMID 1850269 DOI: 10.1016/0006-291X(91)90950-C  0.447
1990 Peale FV, Ishibe Y, Klinge CM, Zain S, Hilf R, Bambara RA. Rapid purification of the estrogen receptor by sequence-specific DNA affinity chromatography. Biochemistry. 28: 8671-5. PMID 2605215 DOI: 10.1021/Bi00448A001  0.426
1990 Klinge CM, Bambara RA, Zain S, Hilf R. Nuclease sensitivity of estradiol-charged estrogen receptor binding sites in nuclei isolated from normal and neoplastic rat mammary tissues. Journal of Steroid Biochemistry. 36: 7-14. PMID 2194077 DOI: 10.1016/0022-4731(90)90108-5  0.384
1989 Klinge CM, Knox DT, Bambara RA, Zain S, Hilf R. Antiestrogen(4-hydroxytamoxifen)-charged estrogen receptor binding to nuclei from normal and neoplastic rat mammary tissues is not affected by host hormonal status. Journal of Steroid Biochemistry. 33: 335-40. PMID 2779224 DOI: 10.1016/0022-4731(89)90321-X  0.366
1987 Lerea CC, Klinge CM, Bambara RA, Zain S, Hilf R. Characterization of a cytosolic inhibitor of calf estrogen receptor binding to nuclei. Endocrinology. 121: 1146-54. PMID 3304979 DOI: 10.1210/Endo-121-3-1146  0.449
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