Walther Mothes - Publications

Yale University, New Haven, CT 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Agosto LM, Herring MB, Mothes W, Henderson AJ. HIV-1-Infected CD4+ T Cells Facilitate Latent Infection of Resting CD4+ T Cells through Cell-Cell Contact. Cell Reports. 24: 2088-2100. PMID 30134170 DOI: 10.1016/j.celrep.2018.07.079  0.56
2016 Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, ... ... Mothes W, et al. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science (New York, N.Y.). 352: 828-33. PMID 27174988 DOI: 10.1126/science.aae0474  0.76
2015 Lascano J, Uchil P, Mothes W, Luban J. TRIM5 retroviral restriction activity correlates with the ability to induce innate immune signaling. Journal of Virology. PMID 26468522 DOI: 10.1128/JVI.02496-15  0.76
2015 Sewald X, Ladinsky MS, Uchil PD, Beloor J, Pi R, Herrmann C, Motamedi N, Murooka TT, Brehm MA, Greiner DL, Shultz LD, Mempel TR, Bjorkman PJ, Kumar P, Mothes W. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science (New York, N.Y.). PMID 26429886 DOI: 10.1126/science.aab2749  0.76
2015 Do Kwon Y, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, ... ... Mothes W, et al. Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nature Structural & Molecular Biology. 22: 522-31. PMID 26098315 DOI: 10.1038/nsmb.3051  0.76
2015 Agosto LM, Uchil PD, Mothes W. HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy. Trends in Microbiology. 23: 289-95. PMID 25766144 DOI: 10.1016/j.tim.2015.02.003  0.76
2015 Munro JB, Mothes W. Structure and Dynamics of the Native HIV-1 Env Trimer. Journal of Virology. 89: 5752-5. PMID 25762739 DOI: 10.1128/JVI.03187-14  0.76
2015 Zeller S, Choi CS, Uchil PD, Ban HS, Siefert A, Fahmy TM, Mothes W, Lee SK, Kumar P. Attachment of cell-binding ligands to arginine-rich cell-penetrating peptides enables cytosolic translocation of complexed siRNA. Chemistry & Biology. 22: 50-62. PMID 25544044 DOI: 10.1016/j.chembiol.2014.11.009  0.76
2014 Munro JB, Gorman J, Ma X, Zhou Z, Arthos J, Burton DR, Koff WC, Courter JR, Smith AB, Kwong PD, Blanchard SC, Mothes W. Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions. Science (New York, N.Y.). 346: 759-63. PMID 25298114 DOI: 10.1126/science.1254426  0.76
2014 Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Huang J, Acharya P, Chuang GY, Ofek G, Stewart-Jones GB, Stuckey J, Bailer RT, Joyce MG, Louder MK, ... ... Mothes W, et al. Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature. 514: 455-61. PMID 25296255 DOI: 10.1038/nature13808  0.76
2014 Uchil PD, Pawliczek T, Reynolds TD, Ding S, Hinz A, Munro JB, Huang F, Floyd RW, Yang H, Hamilton WL, Bewersdorf J, Xiong Y, Calderwood DA, Mothes W. TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly. Journal of Cell Science. 127: 3928-42. PMID 25015296 DOI: 10.1242/jcs.143537  0.76
2014 Munro JB, Mothes W. The HIV-1 Env trimer in HD. Structure (London, England : 1993). 22: 935-6. PMID 25007222 DOI: 10.1016/j.str.2014.06.004  0.76
2014 Li F, Sewald X, Jin J, Sherer NM, Mothes W. Murine leukemia virus Gag localizes to the uropod of migrating primary lymphocytes. Journal of Virology. 88: 10541-55. PMID 24965475 DOI: 10.1128/JVI.01104-14  0.76
2014 Agosto LM, Zhong P, Munro J, Mothes W. Highly active antiretroviral therapies are effective against HIV-1 cell-to-cell transmission. Plos Pathogens. 10: e1003982. PMID 24586176 DOI: 10.1371/journal.ppat.1003982  0.76
2014 Munro JB, Nath A, Färber M, Datta SA, Rein A, Rhoades E, Mothes W. A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles. Journal of Virology. 88: 3577-85. PMID 24403576 DOI: 10.1128/JVI.03353-13  0.76
2013 Garcia ML, Reynolds TD, Mothes W, Robek MD. Functional characterization of the putative hepatitis B virus core protein late domain using retrovirus chimeras. Plos One. 8: e72845. PMID 24009707 DOI: 10.1371/journal.pone.0072845  0.76
2013 Huang F, Hartwich TM, Rivera-Molina FE, Lin Y, Duim WC, Long JJ, Uchil PD, Myers JR, Baird MA, Mothes W, Davidson MW, Toomre D, Bewersdorf J. Video-rate nanoscopy using sCMOS camera-specific single-molecule localization algorithms. Nature Methods. 10: 653-8. PMID 23708387 DOI: 10.1038/nmeth.2488  0.76
2013 Li F, Jin J, Herrmann C, Mothes W. Basic residues in the matrix domain and multimerization target murine leukemia virus Gag to the virological synapse. Journal of Virology. 87: 7113-26. PMID 23616653 DOI: 10.1128/JVI.03263-12  0.76
2013 Zhong P, Agosto LM, Ilinskaya A, Dorjbal B, Truong R, Derse D, Uchil PD, Heidecker G, Mothes W. Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV. Plos One. 8: e53138. PMID 23308151 DOI: 10.1371/journal.pone.0053138  0.76
2013 Zhong P, Agosto LM, Munro JB, Mothes W. Cell-to-cell transmission of viruses. Current Opinion in Virology. 3: 44-50. PMID 23219376 DOI: 10.1016/j.coviro.2012.11.004  0.76
2013 Uchil PD, Hinz A, Siegel S, Coenen-Stass A, Pertel T, Luban J, Mothes W. TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. Journal of Virology. 87: 257-72. PMID 23077300 DOI: 10.1128/JVI.01804-12  0.76
2013 Agosto LM, Zhong P, Mothes W. Cell-to-cell transmission of HIV Advances in Hiv-1 Assembly and Release. 167-184. DOI: 10.1007/978-1-4614-7729-7_7  0.76
2012 Sewald X, Gonzalez DG, Haberman AM, Mothes W. In vivo imaging of virological synapses. Nature Communications. 3: 1320. PMID 23271654 DOI: 10.1038/ncomms2338  0.76
2011 Jin J, Li F, Mothes W. Viral determinants of polarized assembly for the murine leukemia virus. Journal of Virology. 85: 7672-82. PMID 21593177 DOI: 10.1128/JVI.00409-11  0.76
2011 Pertel T, Hausmann S, Morger D, Züger S, Guerra J, Lascano J, Reinhard C, Santoni FA, Uchil PD, Chatel L, Bisiaux A, Albert ML, Strambio-De-Castillia C, Mothes W, Pizzato M, et al. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature. 472: 361-5. PMID 21512573 DOI: 10.1038/nature09976  0.76
2011 Kajaste-Rudnitski A, Marelli SS, Pultrone C, Pertel T, Uchil PD, Mechti N, Mothes W, Poli G, Luban J, Vicenzi E. TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements. Journal of Virology. 85: 5183-96. PMID 21345949 DOI: 10.1128/JVI.02302-10  0.76
2010 Jin J, Sherer N, Mothes W. Surface Transmission or Polarized Egress? Lessons Learned from HTLV Cell-to-Cell Transmission. Viruses. 2: 601-5. PMID 21994650 DOI: 10.3390/v2020601  0.76
2010 Mothes W, Sherer NM, Jin J, Zhong P. Virus cell-to-cell transmission. Journal of Virology. 84: 8360-8. PMID 20375157 DOI: 10.1128/JVI.00443-10  0.76
2010 Sherer NM, Jin J, Mothes W. Directional spread of surface-associated retroviruses regulated by differential virus-cell interactions. Journal of Virology. 84: 3248-58. PMID 20089647 DOI: 10.1128/JVI.02155-09  0.76
2009 Jin J, Sturgeon T, Weisz OA, Mothes W, Montelaro RC. HIV-1 matrix dependent membrane targeting is regulated by Gag mRNA trafficking. Plos One. 4: e6551. PMID 19662089 DOI: 10.1371/journal.pone.0006551  0.76
2009 Jin J, Sherer NM, Heidecker G, Derse D, Mothes W. Assembly of the murine leukemia virus is directed towards sites of cell-cell contact. Plos Biology. 7: e1000163. PMID 19636361 DOI: 10.1371/journal.pbio.1000163  0.76
2009 Uchil PD, Mothes W. HIV Entry Revisited. Cell. 137: 402-4. PMID 19410537 DOI: 10.1016/j.cell.2009.04.033  0.76
2009 Carthagena L, Bergamaschi A, Luna JM, David A, Uchil PD, Margottin-Goguet F, Mothes W, Hazan U, Transy C, Pancino G, Nisole S. Human TRIM gene expression in response to interferons. Plos One. 4: e4894. PMID 19290053 DOI: 10.1371/journal.pone.0004894  0.76
2009 Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F, Greene WC. The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. Journal of Virology. 83: 73-80. PMID 18945786 DOI: 10.1128/JVI.01366-08  0.76
2009 Pertel T, Neagu MR, Hausman S, Zufferey M, Uchil P, Mothes W, Luban J. TRIM5alpha contributes to the anti-viral state Retrovirology. 6: O6.  0.76
2008 Chan R, Uchil PD, Jin J, Shui G, Ott DE, Mothes W, Wenk MR. Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides. Journal of Virology. 82: 11228-38. PMID 18799574 DOI: 10.1128/JVI.00981-08  0.76
2008 Sherer NM, Mothes W. Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis. Trends in Cell Biology. 18: 414-20. PMID 18703335 DOI: 10.1016/j.tcb.2008.07.003  0.76
2008 Chan WT, Sherer NM, Uchil PD, Novak EK, Swank RT, Mothes W. Murine leukemia virus spreading in mice impaired in the biogenesis of secretory lysosomes and Ca2+-regulated exocytosis. Plos One. 3: e2713. PMID 18629000 DOI: 10.1371/journal.pone.0002713  0.76
2008 Uchil PD, Quinlan BD, Chan WT, Luna JM, Mothes W. TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. Plos Pathogens. 4: e16. PMID 18248090 DOI: 10.1371/journal.ppat.0040016  0.76
2007 Münch J, Rücker E, Ständker L, Adermann K, Goffinet C, Schindler M, Wildum S, Chinnadurai R, Rajan D, Specht A, Giménez-Gallego G, Sánchez PC, Fowler DM, Koulov A, Kelly JW, ... Mothes W, et al. Semen-derived amyloid fibrils drastically enhance HIV infection. Cell. 131: 1059-71. PMID 18083097 DOI: 10.1016/j.cell.2007.10.014  0.76
2007 Stahl S, Reinders Y, Asan E, Mothes W, Conzelmann E, Sickmann A, Felbor U. Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes. Biochimica Et Biophysica Acta. 1774: 1237-46. PMID 17765022 DOI: 10.1016/j.bbapap.2007.07.004  0.76
2007 Sherer NM, Lehmann MJ, Jimenez-Soto LF, Horensavitz C, Pypaert M, Mothes W. Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission. Nature Cell Biology. 9: 310-5. PMID 17293854 DOI: 10.1038/ncb1544  0.76
2006 Czibener C, Sherer NM, Becker SM, Pypaert M, Hui E, Chapman ER, Mothes W, Andrews NW. Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes. The Journal of Cell Biology. 174: 997-1007. PMID 16982801 DOI: 10.1083/jcb.200605004  0.76
2005 Lehmann MJ, Sherer NM, Marks CB, Pypaert M, Mothes W. Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells. The Journal of Cell Biology. 170: 317-25. PMID 16027225 DOI: 10.1083/jcb.200503059  0.76
2005 Uchil P, Mothes W. Viral entry: a detour through multivesicular bodies. Nature Cell Biology. 7: 641-2. PMID 15990891 DOI: 10.1038/ncb0705-641  0.76
2005 Melikyan GB, Barnard RJ, Abrahamyan LG, Mothes W, Young JA. Imaging individual retroviral fusion events: from hemifusion to pore formation and growth. Proceedings of the National Academy of Sciences of the United States of America. 102: 8728-33. PMID 15937118 DOI: 10.1073/pnas.0501864102  0.76
2004 Smith JG, Mothes W, Blacklow SC, Cunningham JM. The mature avian leukosis virus subgroup A envelope glycoprotein is metastable, and refolding induced by the synergistic effects of receptor binding and low pH is coupled to infection. Journal of Virology. 78: 1403-10. PMID 14722295 DOI: 10.1128/JVI.78.3.1403-1410.2004  0.76
2003 Sherer NM, Lehmann MJ, Jimenez-Soto LF, Ingmundson A, Horner SM, Cicchetti G, Allen PG, Pypaert M, Cunningham JM, Mothes W. Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. Traffic (Copenhagen, Denmark). 4: 785-801. PMID 14617360 DOI: 10.1034/j.1600-0854.2003.00135.x  0.76
2002 Felbor U, Kessler B, Mothes W, Goebel HH, Ploegh HL, Bronson RT, Olsen BR. Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proceedings of the National Academy of Sciences of the United States of America. 99: 7883-8. PMID 12048238 DOI: 10.1073/pnas.112632299  0.76
2000 Mothes W, Boerger AL, Narayan S, Cunningham JM, Young JA. Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein. Cell. 103: 679-89. PMID 11106737  0.76
2000 Heinrich SU, Mothes W, Brunner J, Rapoport TA. The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain. Cell. 102: 233-44. PMID 10943843  0.76
2000 Felbor U, Dreier L, Bryant RA, Ploegh HL, Olsen BR, Mothes W. Secreted cathepsin L generates endostatin from collagen XVIII. The Embo Journal. 19: 1187-94. PMID 10716919 DOI: 10.1093/emboj/19.6.1187  0.76
1998 Plath K, Mothes W, Wilkinson BM, Stirling CJ, Rapoport TA. Signal sequence recognition in posttranslational protein transport across the yeast ER membrane. Cell. 94: 795-807. PMID 9753326 DOI: 10.1016/S0092-8674(00)81738-9  0.76
1998 Mothes W, Jungnickel B, Brunner J, Rapoport TA. Signal sequence recognition in cotranslational translocation by protein components of the endoplasmic reticulum membrane. The Journal of Cell Biology. 142: 355-64. PMID 9679136 DOI: 10.1083/jcb.142.2.355  0.76
1998 Matlack KE, Mothes W, Rapoport TA. Protein translocation: tunnel vision. Cell. 92: 381-90. PMID 9476897 DOI: 10.1016/S0092-8674(00)80930-7  0.76
1997 Mothes W, Heinrich SU, Graf R, Nilsson I, von Heijne G, Brunner J, Rapoport TA. Molecular mechanism of membrane protein integration into the endoplasmic reticulum. Cell. 89: 523-33. PMID 9160744  0.76
1996 Wiertz EJ, Tortorella D, Bogyo M, Yu J, Mothes W, Jones TR, Rapoport TA, Ploegh HL. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature. 384: 432-8. PMID 8945469 DOI: 10.1038/384432a0  0.76
1994 Mothes W, Prehn S, Rapoport TA. Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane. The Embo Journal. 13: 3973-82. PMID 8076593  0.76
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