Silvia C. Finnemann - Publications

Affiliations: 
1995-2008 Weill Cornell Medical College, New York, NY, United States 
 2008- Fordham University, Bronx, NY, United States 
Area:
Cell Biology, Physiology Biology, General Biophysics
Website:
https://www.fordham.edu/info/24004/biological_sciences_faculty/6846/silvia_c_finnemann

66/71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gao F, Tom E, Lieffrig SA, Finnemann SC, Skowronska-Krawczyk D. A novel quantification method for retinal pigment epithelium phagocytosis using a very-long-chain polyunsaturated fatty acids-based strategy. Frontiers in Molecular Neuroscience. 16: 1279457. PMID 37928068 DOI: 10.3389/fnmol.2023.1279457  0.392
2023 Lieffrig SA, Gyimesi G, Mao Y, Finnemann SC. Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation. Immunological Reviews. PMID 37555340 DOI: 10.1111/imr.13264  0.492
2023 Mercau ME, Akalu YT, Mazzoni F, Gyimesi G, Alberto EJ, Kong Y, Hafler BP, Finnemann SC, Rothlin CV, Ghosh S. Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in -associated retinitis pigmentosa. Science Advances. 9: eade9459. PMID 36662852 DOI: 10.1126/sciadv.ade9459  0.348
2022 Akalu YT, Mercau ME, Ansems M, Hughes LD, Nevin J, Alberto EJ, Liu XN, He LZ, Alvarado D, Keler T, Kong Y, Philbrick WM, Bosenberg M, Finnemann SC, Iavarone A, et al. Tissue-specific modifier alleles determine loss-of-function traits. Elife. 11. PMID 35969037 DOI: 10.7554/eLife.80530  0.321
2022 Bharti K, den Hollander AI, Lakkaraju A, Sinha D, Williams DS, Finnemann SC, Bowes-Rickman C, Malek G, D'Amore PA. Cell culture models to study retinal pigment epithelium-related pathogenesis in age-related macular degeneration. Experimental Eye Research. 222: 109170. PMID 35835183 DOI: 10.1016/j.exer.2022.109170  0.388
2022 Lew DS, McGrath MJ, Finnemann SC. Galectin-3 Promotes Müller Glia Clearance Phagocytosis MERTK and Reduces Harmful Müller Glia Activation in Inherited and Induced Retinal Degeneration. Frontiers in Cellular Neuroscience. 16: 878260. PMID 35711472 DOI: 10.3389/fncel.2022.878260  0.394
2022 Vargas JA, Finnemann SC. Probing Photoreceptor Outer Segment Phagocytosis by the RPE In Vivo: Models and Methodologies. International Journal of Molecular Sciences. 23. PMID 35409021 DOI: 10.3390/ijms23073661  0.333
2021 Mao Y, Finnemann SC. Acute RhoA/Rho Kinase Inhibition Is Sufficient to Restore Phagocytic Capacity to Retinal Pigment Epithelium Lacking the Engulfment Receptor MerTK. Cells. 10. PMID 34440696 DOI: 10.3390/cells10081927  0.376
2021 Mazzoni F, Dun Y, Vargas JA, Nandrot EF, Finnemann SC. Lack of the antioxidant enzyme methionine sulfoxide reductase A in mice impairs RPE phagocytosis and causes photoreceptor cone dysfunction. Redox Biology. 101918. PMID 33674251 DOI: 10.1016/j.redox.2021.101918  0.366
2021 Esposito NJ, Mazzoni F, Vargas JA, Finnemann SC. Diurnal Photoreceptor Outer Segment Renewal in Mice Is Independent of Galectin-3. Investigative Ophthalmology & Visual Science. 62: 7. PMID 33538769 DOI: 10.1167/iovs.62.2.7  0.383
2020 Lew DS, Mazzoni F, Finnemann SC. Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency. Frontiers in Immunology. 11: 1463. PMID 32765507 DOI: 10.3389/Fimmu.2020.01463  0.545
2019 Mazzoni F, Tombo T, Finnemann SC. No Difference Between Age-Matched Male and Female C57BL/6J Mice in Photopic and Scotopic Electroretinogram a- and b-Wave Amplitudes or in Peak Diurnal Outer Segment Phagocytosis by the Retinal Pigment Epithelium. Advances in Experimental Medicine and Biology. 1185: 507-511. PMID 31884662 DOI: 10.1007/978-3-030-27378-1_83  0.366
2019 Yu C, Muñoz LE, Mallavarapu M, Herrmann M, Finnemann SC. Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis. Journal of Cell Science. PMID 31515275 DOI: 10.1242/Jcs.232439  0.752
2019 Mazzoni F, Müller C, DeAssis J, Lew D, Leevy WM, Finnemann SC. Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors. Scientific Reports. 9: 1590. PMID 30733587 DOI: 10.1038/S41598-018-38363-Z  0.459
2019 Mazzoni F, Mao Y, Finnemann SC. Advanced Analysis of Photoreceptor Outer Segment Phagocytosis by RPE Cells in Culture. Methods in Molecular Biology (Clifton, N.J.). 1834: 95-108. PMID 30324439 DOI: 10.1007/978-1-4939-8669-9_7  0.515
2018 Lenis TL, Hu J, Ng SY, Jiang Z, Sarfare S, Lloyd MB, Esposito NJ, Samuel W, Jaworski C, Bok D, Finnemann SC, Radeke MJ, Redmond TM, Travis GH, Radu RA. Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 30397118 DOI: 10.1073/Pnas.1802519115  0.505
2018 Kumawat AK, Yu C, Mann EA, Schridde A, Finnemann SC, Mowat AM. Expression and Characterisation of αvβ5 Integrin on Intestinal Macrophages. European Journal of Immunology. PMID 29676784 DOI: 10.1002/Eji.201747318  0.327
2018 Müller C, Charniga C, Temple S, Finnemann SC. Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium. Stem Cell Reports. PMID 29456184 DOI: 10.1016/J.Stemcr.2018.01.017  0.428
2017 Davis RJ, Alam NM, Zhao C, Müller C, Saini JS, Blenkinsop TA, Mazzoni F, Campbell M, Borden SM, Charniga CJ, Lederman PL, Aguilar V, Naimark M, Fiske M, Boles N, ... ... Finnemann SC, et al. The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue. Stem Cell Reports. PMID 28625537 DOI: 10.1016/J.Stemcr.2017.05.016  0.439
2017 Bulloj A, Maminishkis A, Mizui M, Finnemann SC. Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells. Molecular Neurobiology. PMID 28624895 DOI: 10.1007/S12035-017-0649-5  0.565
2016 Song D, Wilson B, Zhao L, Bhuyan R, Bandyopadhyay M, Lyubarsky A, Yu C, Li Y, Kanu L, Miwa T, Song WC, Finnemann SC, Rohrer B, Dunaief JL. Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration. Plos One. 11: e0166348. PMID 27893831 DOI: 10.1371/Journal.Pone.0166348  0.451
2016 Ploier B, Caro LN, Morizumi T, Pandey K, Pearring JN, Goren MA, Finnemann SC, Graumann J, Arshavsky VY, Dittman JS, Ernst OP, Menon AK. Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants. Nature Communications. 7: 12832. PMID 27694816 DOI: 10.1038/Ncomms12832  0.445
2016 Sethna S, Chamakkala T, Gu X, Thompson TC, Cao G, Elliott MH, Finnemann SC. Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium is Essential for Vision. The Journal of Biological Chemistry. PMID 26814131 DOI: 10.1074/Jbc.M115.687004  0.527
2016 Müller C, Blenkinsop TA, Stern JH, Finnemann SC. Efficiency of Membrane Protein Expression Following Infection with Recombinant Adenovirus of Polarized Non-Transformed Human Retinal Pigment Epithelial Cells. Advances in Experimental Medicine and Biology. 854: 731-7. PMID 26427482 DOI: 10.1007/978-3-319-17121-0_97  0.375
2016 Mao Y, Finnemann SC. Live Imaging of LysoTracker-Labelled Phagolysosomes Tracks Diurnal Phagocytosis of Photoreceptor Outer Segment Fragments in Rat RPE Tissue Ex Vivo. Advances in Experimental Medicine and Biology. 854: 717-23. PMID 26427480 DOI: 10.1007/978-3-319-17121-0_95  0.451
2015 Mao Y, Finnemann SC. Regulation of phagocytosis by Rho GTPases. Small Gtpases. 6: 89-99. PMID 25941749 DOI: 10.4161/21541248.2014.989785  0.399
2014 Parinot C, Rieu Q, Chatagnon J, Finnemann SC, Nandrot EF. Large-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells. Journal of Visualized Experiments : Jove. PMID 25548986 DOI: 10.3791/52100  0.538
2014 Mazzoni F, Safa H, Finnemann SC. Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture. Experimental Eye Research. 126: 51-60. PMID 24780752 DOI: 10.1016/J.Exer.2014.01.010  0.482
2014 Ruggiero L, Finnemann SC. Lack of effect of microfilament or microtubule cytoskeleton-disrupting agents on restriction of externalized phosphatidylserine to rod photoreceptor outer segment tips. Advances in Experimental Medicine and Biology. 801: 91-6. PMID 24664685 DOI: 10.1007/978-1-4614-3209-8_12  0.493
2013 Dun Y, Vargas J, Brot N, Finnemann SC. Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells. Free Radical Biology & Medicine. 65: 1340-51. PMID 24120970 DOI: 10.1016/J.Freeradbiomed.2013.10.006  0.402
2013 Bulloj A, Duan W, Finnemann SC. PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells. Experimental Eye Research. 113: 9-18. PMID 23669303 DOI: 10.1016/J.Exer.2013.05.002  0.435
2013 Mao Y, Finnemann SC. Analysis of photoreceptor outer segment phagocytosis by RPE cells in culture. Methods in Molecular Biology (Clifton, N.J.). 935: 285-95. PMID 23150376 DOI: 10.1007/978-1-62703-080-9_20  0.513
2013 Sethna S, Finnemann SC. Analysis of photoreceptor rod outer segment phagocytosis by RPE cells in situ. Methods in Molecular Biology (Clifton, N.J.). 935: 245-54. PMID 23150373 DOI: 10.1007/978-1-62703-080-9_17  0.488
2012 Ruggiero L, Connor MP, Chen J, Langen R, Finnemann SC. Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina. Proceedings of the National Academy of Sciences of the United States of America. 109: 8145-8. PMID 22566632 DOI: 10.1073/Pnas.1121101109  0.493
2012 Nandrot EF, Silva KE, Scelfo C, Finnemann SC. Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 104: 326-41. PMID 22289110 DOI: 10.1111/Boc.201100076  0.593
2012 Mao Y, Finnemann SC. Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase. Molecular Biology of the Cell. 23: 1104-14. PMID 22262456 DOI: 10.1091/Mbc.E11-10-0840  0.373
2012 Ruggiero L, Sarang Z, Szondy Z, Finnemann SC. αvβ5 integrin-dependent diurnal phagocytosis of shed photoreceptor outer segments by RPE cells is independent of the integrin coreceptor transglutaminase-2. Advances in Experimental Medicine and Biology. 723: 731-7. PMID 22183400 DOI: 10.1007/978-1-4614-0631-0_93  0.574
2012 Ruggiero L, Finnemann SC. Expression of the integrin coreceptor transglutaminase-2 in the RPE in vivo and in culture. Advances in Experimental Medicine and Biology. 723: 709-15. PMID 22183397 DOI: 10.1007/978-1-4614-0631-0_90  0.545
2012 Yu CC, Nandrot EF, Dun Y, Finnemann SC. Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin. Free Radical Biology & Medicine. 52: 660-70. PMID 22178979 DOI: 10.1016/J.Freeradbiomed.2011.11.021  0.429
2010 Mallavarapu M, Finnemann SC. Neural retina and MerTK-independent apical polarity of alphavbeta5 integrin receptors in the retinal pigment epithelium. Advances in Experimental Medicine and Biology. 664: 123-31. PMID 20238010 DOI: 10.1007/978-1-4419-1399-9_15  0.753
2008 Vives-Bauza C, Anand M, Shiraz AK, Shirazi AK, Magrane J, Gao J, Vollmer-Snarr HR, Manfredi G, Finnemann SC. The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells. The Journal of Biological Chemistry. 283: 24770-80. PMID 18621729 DOI: 10.1074/Jbc.M800706200  0.396
2008 Nandrot EF, Finnemann SC. Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function. Ophthalmic Research. 40: 120-3. PMID 18421224 DOI: 10.1159/000119861  0.506
2008 Nandrot EF, Chang Y, Finnemann SC. Alphavbeta5 integrin receptors at the apical surface of the RPE: one receptor, two functions. Advances in Experimental Medicine and Biology. 613: 369-75. PMID 18188966 DOI: 10.1007/978-0-387-74904-4_43  0.773
2007 Chang Y, Finnemann SC. Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis. Journal of Cell Science. 120: 3053-63. PMID 17684062 DOI: 10.1242/Jcs.006361  0.721
2007 Nandrot EF, Anand M, Almeida D, Atabai K, Sheppard D, Finnemann SC. Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12005-10. PMID 17620600 DOI: 10.1073/Pnas.0704756104  0.533
2007 Lakkaraju A, Finnemann SC, Rodriguez-Boulan E. The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 11026-31. PMID 17578916 DOI: 10.1073/Pnas.0702504104  0.596
2006 Finnemann SC, Nandrot EF. MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin. Advances in Experimental Medicine and Biology. 572: 499-503. PMID 17249615 DOI: 10.1007/0-387-32442-9_69  0.466
2006 Nandrot EF, Finnemann SC. Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice. Advances in Experimental Medicine and Biology. 572: 119-23. PMID 17249564 DOI: 10.1007/0-387-32442-9_18  0.529
2006 Sun M, Finnemann SC, Febbraio M, Shan L, Annangudi SP, Podrez EA, Hoppe G, Darrow R, Organisciak DT, Salomon RG, Silverstein RL, Hazen SL. Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions. The Journal of Biological Chemistry. 281: 4222-30. PMID 16354659 DOI: 10.1074/Jbc.M509769200  0.405
2006 Nandrot EF, Anand M, Sircar M, Finnemann SC. Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak. American Journal of Physiology. Cell Physiology. 290: C1256-62. PMID 16338970 DOI: 10.1152/Ajpcell.00480.2005  0.499
2005 Pignataro L, Sitaramayya A, Finnemann SC, Sarthy VP. Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors. Molecular and Cellular Neurosciences. 28: 440-51. PMID 15737735 DOI: 10.1016/J.Mcn.2004.10.004  0.437
2004 Nandrot EF, Kim Y, Brodie SE, Huang X, Sheppard D, Finnemann SC. Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. The Journal of Experimental Medicine. 200: 1539-45. PMID 15596525 DOI: 10.1084/Jem.20041447  0.562
2004 Chowers I, Kim Y, Farkas RH, Gunatilaka TL, Hackam AS, Campochiaro PA, Finnemann SC, Zack DJ. Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake. Investigative Ophthalmology & Visual Science. 45: 2098-106. PMID 15223782 DOI: 10.1167/Iovs.03-0863  0.394
2004 Finnemann SC. Comment on 'Integrin alphavbbeta is not required for the phagocytosis of photoreceptor outer segments by cultured retinal pigment epithelial cells' by M.O. Hall, T.A. Abrams and B.L. Burgess [Exp. Eye Res. 77 (2003) 281-286]. Experimental Eye Research. 78: 309-10; author reply. PMID 14729363 DOI: 10.1016/J.Exer.2003.10.009  0.433
2003 Finnemann SC. Role of alphavbeta5 integrin in regulating phagocytosis by the retinal pigment epithelium. Advances in Experimental Medicine and Biology. 533: 337-42. PMID 15180282 DOI: 10.1007/978-1-4615-0067-4_42  0.514
2003 Finnemann SC. Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors. The Embo Journal. 22: 4143-54. PMID 12912913 DOI: 10.1093/Emboj/Cdg416  0.48
2002 Finnemann SC, Leung LW, Rodriguez-Boulan E. The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America. 99: 3842-7. PMID 11904436 DOI: 10.1073/Pnas.052025899  0.633
2001 Finnemann SC, Silverstein RL. Differential roles of CD36 and αvβ5 integrin in photoreceptor phagocytosis by the retinal pigment epithelium Journal of Experimental Medicine. 194: 1289-1298. PMID 11696594 DOI: 10.1084/Jem.194.9.1289  0.37
1999 Bonilha VL, Finnemann SC, Rodriguez-Boulan E. Ezrin promotes morphogenesis of apical microvilli and basal infoldings in retinal pigment epithelium. The Journal of Cell Biology. 147: 1533-48. PMID 10613910 DOI: 10.1083/Jcb.147.7.1533  0.645
1999 Finnemann SC, Rodriguez-Boulan E. Macrophage and retinal pigment epithelium phagocytosis: apoptotic cells and photoreceptors compete for alphavbeta3 and alphavbeta5 integrins, and protein kinase C regulates alphavbeta5 binding and cytoskeletal linkage. The Journal of Experimental Medicine. 190: 861-74. PMID 10499924 DOI: 10.1084/Jem.190.6.861  0.648
1998 Marmorstein AD, Finnemann SC, Bonilha VL, Rodriguez-Boulan E. Morphogenesis of the retinal pigment epithelium: toward understanding retinal degenerative diseases. Annals of the New York Academy of Sciences. 857: 1-12. PMID 9917828 DOI: 10.1111/J.1749-6632.1998.Tb10102.X  0.634
1998 Marmorstein AD, Gan YC, Bonilha VL, Finnemann SC, Csaky KG, Rodriguez-Boulan E. Apical polarity of N-CAM and EMMPRIN in retinal pigment epithelium resulting from suppression of basolateral signal recognition. The Journal of Cell Biology. 142: 697-710. PMID 9700159 DOI: 10.1083/Jcb.142.3.697  0.64
1997 Finnemann SC, Bonilha VL, Marmorstein AD, Rodriguez-Boulan E. Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization. Proceedings of the National Academy of Sciences of the United States of America. 94: 12932-7. PMID 9371778 DOI: 10.1073/Pnas.94.24.12932  0.574
1997 Finnemann S, Mitrik I, Hess M, Otto G, Wedlich D. Uncoupling of XB/U-cadherin-catenin complex formation from its function in cell-cell adhesion. The Journal of Biological Chemistry. 272: 11856-62. PMID 9115244 DOI: 10.1074/Jbc.272.18.11856  0.318
1997 Kreft B, Berndorff D, Böttinger A, Finnemann S, Wedlich D, Hortsch M, Tauber R, Gessner R. LI-cadherin-mediated cell-cell adhesion does not require cytoplasmic interactions. The Journal of Cell Biology. 136: 1109-21. PMID 9060475 DOI: 10.1083/Jcb.136.5.1109  0.4
1996 Kühl M, Finnemann S, Binder O, Wedlich D. Dominant negative expression of a cytoplasmically deleted mutant of XB/U-cadherin disturbs mesoderm migration during gastrulation in Xenopus laevis. Mechanisms of Development. 54: 71-82. PMID 8808407 DOI: 10.1016/0925-4773(95)00462-9  0.323
Low-probability matches (unlikely to be authored by this person)
1994 Müller HA, Kühl M, Finnemann S, Schneider S, van der Poel SZ, Hausen P, Wedlich D. Xenopus cadherins: the maternal pool comprises distinguishable members of the family. Mechanisms of Development. 47: 213-23. PMID 7531482 DOI: 10.1016/0925-4773(94)90040-X  0.297
2022 Vargas JA, Finnemann SC. Differences in Diurnal Rhythm of Rod Outer Segment Renewal between 129T2/SvEmsJ and C57BL/6J Mice. International Journal of Molecular Sciences. 23. PMID 36012733 DOI: 10.3390/ijms23169466  0.293
1995 Finnemann S, Kühl M, Otto G, Wedlich D. Cadherin transfection of Xenopus XTC cells downregulates expression of substrate adhesion molecules. Molecular and Cellular Biology. 15: 5082-91. PMID 7651425 DOI: 10.1128/MCB.15.9.5082  0.257
1993 Finnemann S, Kremsner PG, Chaves MF, Schumacher C, Neifer S, Bienzle U. Antibody response in Plasmodium vinckei malaria after treatment with chloroquine and adjuvant interferon-gamma. Parasitology Research. 78: 629-34. PMID 1480597 DOI: 10.1007/BF00931511  0.053
2022 Rocks D, Shukla M, Ouldibbat L, Finnemann SC, Kalluchi A, Rowley MJ, Kundakovic M. Sex-specific multi-level 3D genome dynamics in the mouse brain. Nature Communications. 13: 3438. PMID 35705546 DOI: 10.1038/s41467-022-30961-w  0.051
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