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Marc M. Greenberg - Publications

Affiliations: 
Chemistry Johns Hopkins University, Baltimore, MD 
Area:
reactivity, function, structure, and uses of nucleic acids
Website:
http://www.jhu.edu/chem/greenberg/Marc.html

223 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gao S, Oden PN, Ryan BJ, Yang H, Freudenthal BD, Greenberg MM. Biochemical and Structural Characterization of Fapy•dG Replication by Human DNA Polymerase β. Biorxiv : the Preprint Server For Biology. PMID 38293220 DOI: 10.1101/2024.01.15.575758  0.348
2023 Wen T, Kermarrec M, Dumont E, Gillet N, Greenberg MM. DNA-Histone Cross-Link Formation via Hole Trapping in Nucleosome Core Particles. Journal of the American Chemical Society. 145: 23702-23714. PMID 37856159 DOI: 10.1021/jacs.3c08135  0.381
2023 Bacurio JHT, Gao S, Yang H, Basu AK, Greenberg MM. Synergistic effects on mutagenicity of tandem lesions containing 8-oxo-7,8-dihydro-2'-deoxyguanosine or Fapy•dG flanked by a 3' 5-formyl-2'-deoxyuridine in human cells. Dna Repair. 129: 103527. PMID 37467631 DOI: 10.1016/j.dnarep.2023.103527  0.327
2023 Peng H, Vu S, Retes P, Ward S, Kumar A, Sevilla MD, Adhikary A, Greenberg MM. Photochemical and Single Electron Transfer Generation of 2'-Deoxycytidin-4-yl Radical from Oxime Esters. The Journal of Organic Chemistry. PMID 37220149 DOI: 10.1021/acs.joc.3c00646  0.342
2022 Ryan BJ, Yang H, Bacurio JHT, Smith MR, Basu AK, Greenberg MM, Freudenthal BD. Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication. Journal of the American Chemical Society. PMID 35499923 DOI: 10.1021/jacs.2c00193  0.33
2022 Jacinto MP, Fried SD, Greenberg MM. Intracellular Formation of a DNA Damage-Induced, Histone Post-Translational Modification Following Bleomycin Treatment. Journal of the American Chemical Society. 144: 7600-7605. PMID 35467863 DOI: 10.1021/jacs.2c02880  0.338
2022 Ren M, Greenberg MM, Zhou C. Participation of Histones in DNA Damage and Repair within Nucleosome Core Particles: Mechanism and Applications. Accounts of Chemical Research. 55: 1059-1073. PMID 35271268 DOI: 10.1021/acs.accounts.2c00041  0.399
2021 Peng H, Jie J, Mortimer IP, Ma Z, Su H, Greenberg MM. Reactivity and DNA Damage by Independently Generated 2'-Deoxycytidin-4-yl Radical. Journal of the American Chemical Society. PMID 34467764 DOI: 10.1021/jacs.1c06425  0.403
2020 Zheng L, Greenberg MM. Independent Generation and Reactivity of 2'-Deoxyguanosin-1-yl Radical. The Journal of Organic Chemistry. PMID 32525316 DOI: 10.1021/Acs.Joc.0C01095  0.406
2020 Korman A, Sun H, Hua B, Yang H, Capilato JN, Paul R, Panja S, Ha T, Greenberg MM, Woodson SA. Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space. Proceedings of the National Academy of Sciences of the United States of America. PMID 32430319 DOI: 10.1073/Pnas.2003425117  0.753
2020 Yang H, Tang JA, Greenberg MM. Synthesis of Oligonucleotides Containing the N -(2-Deoxy-α,β-d-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapy⋅dG) Oxidative Damage Product Derived from 2'-Deoxyguanosine. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32271495 DOI: 10.1002/Chem.201905795  0.493
2020 Zheng L, Greenberg MM. Independent Generationand Reactivity of 2′-Deoxyguanosin‑N1‑yl Radical Journal of Organic Chemistry. DOI: 10.1021/Acs.Joc.0C01095.S001  0.378
2019 Naldiga S, Huang H, Greenberg MM, Basu AK. Mutagenic Effects of a 2-Deoxyribonolactone -Thymine Glycol Tandem DNA Lesion in Human Cells. Biochemistry. PMID 31860280 DOI: 10.1021/Acs.Biochem.9B01058  0.417
2019 Yang K, Sun H, Lowder L, Varadarajan S, Greenberg MM. Reactivity of N3-Methyl-2'-Deoxyadenosine in Nucleosome Core Particles. Chemical Research in Toxicology. PMID 31565933 DOI: 10.1021/Acs.Chemrestox.9B00299  0.767
2019 Yang K, Greenberg MM. DNA-Protein Cross-Link Formation in Nucleosome Core Particles Treated with Methyl Methanesulfonate. Chemical Research in Toxicology. PMID 31532638 DOI: 10.1021/Acs.Chemrestox.9B00314  0.46
2019 Sun H, Zheng L, Yang K, Greenberg MM. Positional Dependence of DNA Hole Transfer Efficiency in Nucleosome Core Particles. Journal of the American Chemical Society. PMID 31244168 DOI: 10.1021/Jacs.9B03686  0.763
2019 Yang K, Prasse C, Greenberg MM. Effect of Histone Lysine Methylation on DNA Lesion Reactivity in Nucleosome Core Particles. Chemical Research in Toxicology. PMID 30916939 DOI: 10.1021/Acs.Chemrestox.9B00049  0.409
2019 Smith MR, Shock DD, Beard WA, Greenberg MM, Freudenthal BD, Wilson SH. A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Research. PMID 30649431 DOI: 10.1093/nar/gkz002  0.476
2018 Rana A, Yang K, Greenberg MM. Reactivity of the Major Product of C5'-Oxidative DNA Damage in Nucleosome Core Particles. Chembiochem : a European Journal of Chemical Biology. PMID 30444560 DOI: 10.1002/Cbic.201800663  0.41
2018 Yang K, Park D, Tretyakova NY, Greenberg MM. Histone tails decrease N7-methyl-2'-deoxyguanosine depurination and yield DNA-protein cross-links in nucleosome core particles and cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30429328 DOI: 10.1073/Pnas.1813338115  0.461
2018 Bai J, Zhang Y, Xi Z, Greenberg MM, Zhou C. Oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine leads to substantial DNA-histone cross-links within nucleosome core particles. Chemical Research in Toxicology. PMID 30412392 DOI: 10.1021/Acs.Chemrestox.8B00244  0.511
2018 Yang K, Greenberg MM. Histone Tail Sequences Balance Their Role in Genetic Regulation and the Need to Protect DNA Against Destruction in Nucleosome Core Particles Containing Abasic Sites. Chembiochem : a European Journal of Chemical Biology. PMID 30307690 DOI: 10.1002/Cbic.201800559  0.473
2018 Laverty DJ, Greenberg MM. Expanded Substrate Scope of DNA Polymerase θ and DNA Polymerase β: Lyase Activity on 5'-Overhangs and Clustered Lesions. Biochemistry. PMID 30299084 DOI: 10.1021/Acs.Biochem.8B00911  0.483
2018 Sun H, Zheng L, Greenberg MM. Independent Generation of Reactive Intermediates Leads to an Alternative Mechanism for Strand Damage Induced by Hole Transfer in Poly(dA-T) Sequences. Journal of the American Chemical Society. PMID 30169029 DOI: 10.1021/Jacs.8B05484  0.779
2018 Jacinto MP, Pichling P, Greenberg MM. Synthesis of 5-Methylene-2-pyrrolones. Organic Letters. PMID 30063360 DOI: 10.1021/Acs.Orglett.8B02030  0.301
2018 Yang K, Greenberg MM. Enhanced Cleavage at Abasic Sites Within Clustered Lesions in Nucleosome Core Particles. Chembiochem : a European Journal of Chemical Biology. PMID 30043401 DOI: 10.1002/Cbic.201800338  0.415
2018 Laverty DJ, Mortimer IP, Greenberg MM. Mechanistic Insight through Irreversible Inhibition: DNA Polymerase θ Uses a Common Active Site for Polymerase and Lyase Activities. Journal of the American Chemical Society. PMID 29998737 DOI: 10.1021/Jacs.8B04158  0.491
2018 Wang R, Yang K, Banerjee S, Greenberg MM. Rotational Effects within Nucleosome Core Particles on Abasic Site Reactivity. Biochemistry. PMID 29894168 DOI: 10.1021/Acs.Biochem.8B00493  0.746
2018 Zheng L, Greenberg MM. Traceless Tandem Lesion Formation in DNA from a Nitrogen-Centered Purine Radical. Journal of the American Chemical Society. PMID 29738242 DOI: 10.1021/Jacs.8B02828  0.516
2018 Beaver JM, Lai Y, Rolle SJ, Weng L, Greenberg MM, Liu Y. An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleotide repeat tract. Plos One. 13: e0192148. PMID 29389977 DOI: 10.1371/Journal.Pone.0192148  0.537
2018 Paul R, Banerjee S, Greenberg MM. Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells. Acs Chemical Biology. PMID 29368921 DOI: 10.1021/acschembio.8b00048  0.766
2017 Laverty DJ, Greenberg MM. In Vitro Bypass of Thymidine Glycol by DNA Polymerase θ Forms Sequence-Dependent Frameshift Mutations. Biochemistry. 56: 6726-6733. PMID 29243925 DOI: 10.1021/Acs.Biochem.7B01093  0.508
2017 Zheng L, Greenberg MM. DNA Damage Emanating From a Neutral Purine Radical Reveals the Sequence Dependent Convergence of the Direct and Indirect Effects of γ-Radiolysis. Journal of the American Chemical Society. 139: 17751-17754. PMID 29190086 DOI: 10.1021/Jacs.7B10942  0.506
2017 Zheng L, Lin L, Qu K, Adhikary A, Sevilla MD, Greenberg MM. Independent Photochemical Generation and Reactivity of Nitrogen-Centered Purine Nucleoside Radicals from Hydrazines. Organic Letters. PMID 29125775 DOI: 10.1021/Acs.Orglett.7B03368  0.416
2017 Sun H, Taverna Porro ML, Greenberg MM. Independent Generation and Reactivity of Thymidine Radical Cations. The Journal of Organic Chemistry. PMID 28994287 DOI: 10.1021/Acs.Joc.7B02017  0.752
2017 Li F, Zhang Y, Bai J, Greenberg MM, Xi Z, Zhou C. 5-Formylcytosine Yields DNA-Protein Cross-Links in Nucleosome Core Particles. Journal of the American Chemical Society. PMID 28742335 DOI: 10.1021/Jacs.7B05495  0.416
2017 Hida N, Aboukilila MY, Burow DA, Paul R, Greenberg MM, Fazio M, Beasley S, Spitale RC, Cleary MD. EC-tagging allows cell type-specific RNA analysis. Nucleic Acids Research. PMID 28641402 DOI: 10.1093/Nar/Gkx551  0.499
2017 Paul R, Banerjee S, Greenberg MM. Synergistic Effects of an Irreversible DNA Polymerase Inhibitor and DNA Damaging Agents on HeLa Cells. Acs Chemical Biology. PMID 28459532 DOI: 10.1021/Acschembio.7B00259  0.78
2017 Laverty DJ, Averill AM, Doublié S, Greenberg MM. The A-Rule and Deletion Formation During Abasic and Oxidized Abasic Site Bypass by DNA Polymerase θ. Acs Chemical Biology. PMID 28459528 DOI: 10.1021/Acschembio.7B00211  0.434
2017 Zheng L, Griesser M, Pratt DA, Greenberg MM. Aminyl Radical Generation via Tandem Norrish Type I Photocleavage, β-Fragmentation: Independent Generation and Reactivity of the 2'-Deoxyadenosin- N6-yl Radical. The Journal of Organic Chemistry. PMID 28318253 DOI: 10.1021/Acs.Joc.7B00093  0.333
2017 Drohat AC, Pidugu LS, Flowers JW, Coey CT, Pozharski E, Greenberg MM. Enzymatic removal of epigenetic marks from DNA Acta Crystallographica Section a Foundations and Advances. 73: a325-a325. DOI: 10.1107/S0108767317096829  0.451
2016 Banerjee S, Chakraborty S, Jacinto MP, Paul MD, Balster MV, Greenberg MM. Probing Enhanced Double-Strand Break Formation at Abasic Sites within Clustered Lesions in Nucleosome Core Particles. Biochemistry. PMID 28005342 DOI: 10.1021/Acs.Biochem.6B01144  0.735
2016 Cheng B, Zhou Q, Weng L, Leszyk JD, Greenberg MM, Tse-Dinh YC. Identification of proximal sites for unwound DNA substrate in E. coli topoisomerase I with oxidative crosslinking. Febs Letters. PMID 27926785 DOI: 10.1002/1873-3468.12517  0.515
2016 Greenberg MM. Pyrimidine Nucleobase Radical Reactivity in DNA and RNA. Radiation Physics and Chemistry (Oxford, England : 1993). 128: 82-91. PMID 27812242 DOI: 10.1016/J.Radphyschem.2016.06.003  0.358
2016 Pidugu LS, Flowers JW, Coey CT, Pozharski E, Greenberg MM, Drohat AC. Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase. Biochemistry. PMID 27805810 DOI: 10.1021/Acs.Biochem.6B00982  0.503
2016 Paul R, Greenberg MM. Mechanistic Studies on RNA Strand Scission from a C2'-Radical. The Journal of Organic Chemistry. PMID 27668445 DOI: 10.1021/Acs.Joc.6B01760  0.596
2015 Xu W, Ouellette AM, Ghosh S, O' Neill TC, Greenberg MM, Zhao L. Mutagenic Bypass of an Oxidized Abasic Lesion-Induced DNA Interstrand Cross-link Analogue by Human Translesion Synthesis DNA Polymerases. Biochemistry. PMID 26626537 DOI: 10.1021/Acs.Biochem.5B01027  0.853
2015 Rudra A, Hou D, Zhang Y, Coulter J, Zhou H, DeWeese TL, Greenberg MM. Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases. The Journal of Organic Chemistry. 80: 10675-85. PMID 26509218 DOI: 10.1021/Acs.Joc.5B01833  0.662
2015 Ghosh S, Greenberg MM. Correlation of Thermal Stability and Structural Distortion of DNA Interstrand Cross-Links Produced from Oxidized Abasic Sites with Their Selective Formation and Repair. Biochemistry. PMID 26426430 DOI: 10.1021/Acs.Biochem.5B00860  0.832
2015 Weng L, Greenberg MM. Rapid Histone-Catalyzed DNA Lesion Excision and Accompanying Protein Modification in Nucleosomes and Nucleosome Core Particles. Journal of the American Chemical Society. 137: 11022-31. PMID 26290445 DOI: 10.1021/Jacs.5B05478  0.536
2015 Hong IS, Greenberg MM. Sequence selective tagging of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) using PNAs. Bioorganic & Medicinal Chemistry Letters. PMID 26051648 DOI: 10.1016/J.Bmcl.2015.05.042  0.518
2015 Panja S, Paul R, Greenberg MM, Woodson SA. Light-Triggered RNA Annealing by an RNA Chaperone. Angewandte Chemie (International Ed. in English). 54: 7281-4. PMID 25959666 DOI: 10.1002/Anie.201501658  0.488
2015 Taverna Porro ML, Greenberg MM. Double-strand breaks from a radical commonly produced by DNA-damaging agents. Chemical Research in Toxicology. 28: 810-6. PMID 25749510 DOI: 10.1021/Acs.Chemrestox.5B00032  0.496
2015 Paul R, Greenberg MM. Rapid RNA strand scission following C2'-hydrogen atom abstraction. Journal of the American Chemical Society. 137: 596-9. PMID 25580810 DOI: 10.1021/Ja511401G  0.601
2015 Weng L, Zhou C, Greenberg MM. Probing interactions between lysine residues in histone tails and nucleosomal DNA via product and kinetic analysis. Acs Chemical Biology. 10: 622-30. PMID 25475712 DOI: 10.1021/Cb500737Y  0.478
2014 Paul R, Greenberg MM. Independent generation and reactivity of uridin-2'-yl radical. The Journal of Organic Chemistry. 79: 10303-10. PMID 25325847 DOI: 10.1021/Jo501916R  0.547
2014 Sloane JL, Greenberg MM. Interstrand cross-link and bioconjugate formation in RNA from a modified nucleotide. The Journal of Organic Chemistry. 79: 9792-8. PMID 25295850 DOI: 10.1021/Jo501982R  0.374
2014 Ghosh S, Greenberg MM. Nucleotide excision repair of chemically stabilized analogues of DNA interstrand cross-links produced from oxidized abasic sites. Biochemistry. 53: 5958-65. PMID 25208227 DOI: 10.1021/Bi500914D  0.84
2014 Ghosh S, Greenberg MM. Synthesis of cross-linked DNA containing oxidized abasic site analogues. The Journal of Organic Chemistry. 79: 5948-57. PMID 24949656 DOI: 10.1021/Jo500944G  0.835
2014 Bajacan JE, Hong IS, Penning TM, Penning TW, Greenberg MM. Quantitative detection of 8-Oxo-7,8-dihydro-2'-deoxyguanosine using chemical tagging and qPCR. Chemical Research in Toxicology. 27: 1227-35. PMID 24932862 DOI: 10.1021/Tx500120P  0.441
2014 Greenberg MM. Looking beneath the surface to determine what makes DNA damage deleterious. Current Opinion in Chemical Biology. 21: 48-55. PMID 24762292 DOI: 10.1016/J.Cbpa.2014.03.018  0.53
2014 Zhou C, Greenberg MM. DNA damage by histone radicals in nucleosome core particles. Journal of the American Chemical Society. 136: 6562-5. PMID 24754228 DOI: 10.1021/Ja501285S  0.388
2014 Cunniffe S, O'Neill P, Greenberg MM, Lomax ME. Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions. Mutation Research. 762: 32-9. PMID 24631220 DOI: 10.1016/J.Mrfmmm.2014.02.005  0.467
2014 San Pedro JM, Greenberg MM. 5,6-Dihydropyrimidine peroxyl radical reactivity in DNA. Journal of the American Chemical Society. 136: 3928-36. PMID 24579910 DOI: 10.1021/Ja412562P  0.476
2014 Hou D, Greenberg MM. DNA interstrand cross-linking upon irradiation of aryl halide C-nucleotides. The Journal of Organic Chemistry. 79: 1877-84. PMID 24559326 DOI: 10.1021/Jo4028227  0.538
2014 Arian D, Hedayati M, Zhou H, Bilis Z, Chen K, DeWeese TL, Greenberg MM. Irreversible inhibition of DNA polymerase β by small-molecule mimics of a DNA lesion. Journal of the American Chemical Society. 136: 3176-83. PMID 24517090 DOI: 10.1021/Ja411733S  0.502
2014 Greenberg MM. Abasic and oxidized abasic site reactivity in DNA: enzyme inhibition, cross-linking, and nucleosome catalyzed reactions. Accounts of Chemical Research. 47: 646-55. PMID 24369694 DOI: 10.1021/Ar400229D  0.586
2014 Ghosh S, Greenberg MM. Correction to Nucleotide Excision Repair of Chemically Stabilized Analogues of DNA Interstrand Cross-Links Produced from Oxidized Abasic Sites Biochemistry. 53: 6418-6418. DOI: 10.1021/bi501162v  0.396
2013 Taverna Porro ML, Greenberg MM. DNA double strand cleavage via interstrand hydrogen atom abstraction. Journal of the American Chemical Society. 135: 16368-71. PMID 24147577 DOI: 10.1021/Ja409513Q  0.494
2013 Bajacan JE, Greenberg MM. DNA polymerase V kinetics support the instructive nature of an oxidized abasic lesion in Escherichia coli. Biochemistry. 52: 6301-3. PMID 24015801 DOI: 10.1021/Bi400997H  0.448
2013 San Pedro JM, Greenberg MM. Photochemical control of DNA structure through radical disproportionation. Chembiochem : a European Journal of Chemical Biology. 14: 1590-6. PMID 23940105 DOI: 10.1002/Cbic.201300369  0.506
2013 Weng L, Horvat SM, Schiesser CH, Greenberg MM. Deconvoluting the reactivity of two intermediates formed from modified pyrimidines. Organic Letters. 15: 3618-21. PMID 23822109 DOI: 10.1021/Ol401472M  0.425
2013 Zhou C, Sczepanski JT, Greenberg MM. Histone modification via rapid cleavage of C4'-oxidized abasic sites in nucleosome core particles. Journal of the American Chemical Society. 135: 5274-7. PMID 23531104 DOI: 10.1021/Ja400915W  0.757
2013 Sczepanski JT, Zhou C, Greenberg MM. Nucleosome core particle-catalyzed strand scission at abasic sites. Biochemistry. 52: 2157-64. PMID 23480734 DOI: 10.1021/Bi3010076  0.717
2013 Stevens AJ, Guan L, Bebenek K, Kunkel TA, Greenberg MM. DNA polymerase λ inactivation by oxidized abasic sites. Biochemistry. 52: 975-83. PMID 23330920 DOI: 10.1021/Bi301592X  0.712
2013 Crespan E, Pasi E, Imoto S, Hübscher U, Greenberg MM, Maga G. Human DNA polymerase β, but not λ, can bypass a 2-deoxyribonolactone lesion together with proliferating cell nuclear antigen. Acs Chemical Biology. 8: 336-44. PMID 23101935 DOI: 10.1021/Cb300542K  0.505
2013 Hedayati M, Arian D, Zhou H, Bilis Z, Chen K, Greenberg M, DeWeese T. Evaluation of Novel DNA Polymerase Beta Inhibitors as Potential Radiosensitizers of Prostate Cancer Cells International Journal of Radiation Oncology*Biology*Physics. 87: S656. DOI: 10.1016/J.Ijrobp.2013.06.1738  0.341
2012 Zhou C, Sczepanski JT, Greenberg MM. Mechanistic studies on histone catalyzed cleavage of apyrimidinic/apurinic sites in nucleosome core particles. Journal of the American Chemical Society. 134: 16734-41. PMID 23020793 DOI: 10.1021/Ja306858M  0.784
2012 Resendiz MJ, Schön A, Freire E, Greenberg MM. Photochemical control of RNA structure by disrupting π-stacking. Journal of the American Chemical Society. 134: 12478-81. PMID 22827464 DOI: 10.1021/Ja306304W  0.319
2012 San Pedro JM, Beerman TA, Greenberg MM. DNA damage by C1027 involves hydrogen atom abstraction and addition to nucleobases. Bioorganic & Medicinal Chemistry. 20: 4744-50. PMID 22748380 DOI: 10.1016/J.Bmc.2012.06.004  0.521
2012 Zhang B, Guo LH, Greenberg MM. Quantification of 8-oxodGuo lesions in double-stranded DNA using a photoelectrochemical DNA sensor. Analytical Chemistry. 84: 6048-53. PMID 22746252 DOI: 10.1021/Ac300866U  0.533
2012 San Pedro JM, Greenberg MM. Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine. Organic Letters. 14: 2866-9. PMID 22616940 DOI: 10.1021/Ol301109Z  0.393
2012 Zhou C, Greenberg MM. Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone. Journal of the American Chemical Society. 134: 8090-3. PMID 22551239 DOI: 10.1021/Ja302993H  0.528
2012 Resendiz MJ, Pottiboyina V, Sevilla MD, Greenberg MM. Direct strand scission in double stranded RNA via a C5-pyrimidine radical. Journal of the American Chemical Society. 134: 3917-24. PMID 22335525 DOI: 10.1021/Ja300044E  0.403
2012 Cadet J, Loft S, Olinski R, Evans MD, Bialkowski K, Richard Wagner J, Dedon PC, Møller P, Greenberg MM, Cooke MS. Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids. Free Radical Research. 46: 367-81. PMID 22263561 DOI: 10.3109/10715762.2012.659248  0.445
2012 Greenberg MM. The formamidopyrimidines: purine lesions formed in competition with 8-oxopurines from oxidative stress. Accounts of Chemical Research. 45: 588-97. PMID 22077696 DOI: 10.1021/Ar2002182  0.543
2011 Guan L, Greenberg MM. An Oxidized Abasic Lesion as an Intramolecular Source of DNA Adducts. Australian Journal of Chemistry. 64: 438-442. PMID 25392543 DOI: 10.1071/Ch10420  0.668
2011 Sczepanski JT, Hiemstra CN, Greenberg MM. Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides. Bioorganic & Medicinal Chemistry. 19: 5788-93. PMID 21903404 DOI: 10.1016/J.Bmc.2011.08.024  0.765
2011 Guan L, van der Heijden GW, Bortvin A, Greenberg MM. Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine. Chembiochem : a European Journal of Chemical Biology. 12: 2184-90. PMID 21805552 DOI: 10.1002/Cbic.201100353  0.675
2011 Jung KY, Kodama T, Greenberg MM. Repair of the major lesion resulting from C5'-oxidation of DNA. Biochemistry. 50: 6273-9. PMID 21696131 DOI: 10.1021/Bi200787E  0.562
2011 Jacobs AC, Resendiz MJ, Greenberg MM. Product and mechanistic analysis of the reactivity of a C6-pyrimidine radical in RNA. Journal of the American Chemical Society. 133: 5152-9. PMID 21391681 DOI: 10.1021/Ja200317W  0.424
2011 Jacobs AC, Kreller CR, Greenberg MM. Long patch base excision repair compensates for DNA polymerase β inactivation by the C4'-oxidized abasic site. Biochemistry. 50: 136-43. PMID 21155533 DOI: 10.1021/Bi1017667  0.58
2011 Guan L, van der Heijden GW, Bortvin A, Greenberg MM. Corrigendum: Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine Chembiochem. 12: 2110. DOI: 10.1002/Cbic.201190066  0.61
2010 Sczepanski JT, Wong RS, McKnight JN, Bowman GD, Greenberg MM. Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle. Proceedings of the National Academy of Sciences of the United States of America. 107: 22475-80. PMID 21149689 DOI: 10.1073/Pnas.1012860108  0.786
2010 Guan L, Bebenek K, Kunkel TA, Greenberg MM. Inhibition of short patch and long patch base excision repair by an oxidized abasic site. Biochemistry. 49: 9904-10. PMID 20961055 DOI: 10.1021/Bi101533A  0.697
2010 Fülöp A, Peng X, Greenberg MM, Mokhir A. A nucleic acid-directed, red light-induced chemical reaction. Chemical Communications (Cambridge, England). 46: 5659-61. PMID 20574574 DOI: 10.1039/C0Cc00744G  0.496
2010 Guan L, Greenberg MM. Irreversible inhibition of DNA polymerase beta by an oxidized abasic lesion. Journal of the American Chemical Society. 132: 5004-5. PMID 20334373 DOI: 10.1021/Ja101372C  0.681
2010 Cooke MS, Loft S, Olinski R, Evans MD, Bialkowski K, Wagner JR, Dedon PC, Møller P, Greenberg MM, Cadet J. Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA. Chemical Research in Toxicology. 23: 705-7. PMID 20235554 DOI: 10.1021/Tx1000706  0.331
2010 Wong RS, Sczepanski JT, Greenberg MM. Excision of a lyase-resistant oxidized abasic lesion from DNA. Chemical Research in Toxicology. 23: 766-70. PMID 20232790 DOI: 10.1021/Tx9003984  0.787
2010 Jacobs AC, Resendiz MJ, Greenberg MM. Direct strand scission from a nucleobase radical in RNA. Journal of the American Chemical Society. 132: 3668-9. PMID 20184313 DOI: 10.1021/Ja100281X  0.333
2010 Ding H, Greenberg MM. DNA damage and interstrand cross-link formation upon irradiation of aryl iodide C-nucleotide analogues. The Journal of Organic Chemistry. 75: 535-44. PMID 20067226 DOI: 10.1021/Jo902071Y  0.542
2010 Peng X, Ghosh AK, Van Houten B, Greenberg MM. Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks. Biochemistry. 49: 11-9. PMID 20000382 DOI: 10.1021/Bi901603H  0.658
2009 Guan L, Greenberg MM. DNA interstrand cross-link formation by the 1,4-dioxobutane abasic lesion. Journal of the American Chemical Society. 131: 15225-31. PMID 19807122 DOI: 10.1021/Ja9061695  0.705
2009 Sczepanski JT, Jacobs AC, Majumdar A, Greenberg MM. Scope and mechanism of interstrand cross-link formation by the C4'-oxidized abasic site. Journal of the American Chemical Society. 131: 11132-9. PMID 19722676 DOI: 10.1021/Ja903404V  0.785
2009 Newman CA, Resendiz MJ, Sczepanski JT, Greenberg MM. Photochemical generation and reactivity of the 5,6-dihydrouridin-6-yl radical. The Journal of Organic Chemistry. 74: 7007-12. PMID 19691299 DOI: 10.1021/Jo9012805  0.7
2009 Huang H, Imoto S, Greenberg MM. The mutagenicity of thymidine glycol in Escherichia coli is increased when it is part of a tandem lesion. Biochemistry. 48: 7833-41. PMID 19618962 DOI: 10.1021/Bi900927D  0.485
2009 Sczepanski JT, Jacobs AC, Van Houten B, Greenberg MM. Double-strand break formation during nucleotide excision repair of a DNA interstrand cross-link. Biochemistry. 48: 7565-7. PMID 19606890 DOI: 10.1021/Bi901006B  0.787
2009 Huang H, Stivers JT, Greenberg MM. Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase. Journal of the American Chemical Society. 131: 1344-5. PMID 19173657 DOI: 10.1021/Ja807705Z  0.503
2008 Ding H, Majumdar A, Tolman JR, Greenberg MM. Multinuclear NMR and kinetic analysis of DNA interstrand cross-link formation. Journal of the American Chemical Society. 130: 17981-7. PMID 19053196 DOI: 10.1021/Ja807845N  0.503
2008 Peng X, Pigli YZ, Rice PA, Greenberg MM. Protein binding has a large effect on radical mediated DNA damage. Journal of the American Chemical Society. 130: 12890-1. PMID 18778053 DOI: 10.1021/Ja805440V  0.66
2008 Bastia D, Zzaman S, Krings G, Saxena M, Peng X, Greenberg MM. Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase. Proceedings of the National Academy of Sciences of the United States of America. 105: 12831-6. PMID 18708526 DOI: 10.1073/Pnas.0805898105  0.631
2008 Peng X, Hong IS, Li H, Seidman MM, Greenberg MM. Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidines. Journal of the American Chemical Society. 130: 10299-306. PMID 18620398 DOI: 10.1021/Ja802177U  0.643
2008 Sczepanski JT, Jacobs AC, Greenberg MM. Self-promoted DNA interstrand cross-link formation by an abasic site. Journal of the American Chemical Society. 130: 9646-7. PMID 18593126 DOI: 10.1021/Ja8030642  0.778
2008 Huang H, Greenberg MM. Hydrogen bonding contributes to the selectivity of nucleotide incorporation opposite an oxidized abasic lesion. Journal of the American Chemical Society. 130: 6080-1. PMID 18412345 DOI: 10.1021/Ja801715C  0.485
2008 Imoto S, Bransfield LA, Croteau DL, Van Houten B, Greenberg MM. DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair. Biochemistry. 47: 4306-16. PMID 18341293 DOI: 10.1021/Bi7021427  0.514
2008 Huang H, Greenberg MM. Synthesis and analysis of oligonucleotides containing abasic site analogues. The Journal of Organic Chemistry. 73: 2695-703. PMID 18324835 DOI: 10.1021/Jo702614P  0.513
2008 Peng X, Greenberg MM. Facile SNP detection using bifunctional, cross-linking oligonucleotide probes. Nucleic Acids Research. 36: e31. PMID 18281702 DOI: 10.1093/Nar/Gkn052  0.582
2008 Weledji YN, Wiederholt CJ, Delaney MO, Greenberg MM. DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG. Bioorganic & Medicinal Chemistry. 16: 4029-34. PMID 18242999 DOI: 10.1016/J.Bmc.2008.01.025  0.814
2008 Krishnamurthy N, Haraguchi K, Greenberg MM, David SS. Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases. Biochemistry. 47: 1043-50. PMID 18154319 DOI: 10.1021/Bi701619U  0.439
2008 Greenberg MM. Mechanistic studies and applications of DNA damage using nucleotide probes Collection of Czechoslovak Chemical Communications. 10: 17-24. DOI: 10.1135/Css200810017  0.466
2007 Ding H, Greenberg MM. Gamma-radiolysis and hydroxyl radical produce interstrand cross-links in DNA involving thymidine. Chemical Research in Toxicology. 20: 1623-8. PMID 17939740 DOI: 10.1021/Tx7002307  0.466
2007 Chowdhury G, Junnotula V, Daniels JS, Greenberg MM, Gates KS. DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2). Journal of the American Chemical Society. 129: 12870-7. PMID 17900117 DOI: 10.1021/Ja074432M  0.714
2007 Patro JN, Wiederholt CJ, Jiang YL, Delaney JC, Essigmann JM, Greenberg MM. Studies on the replication of the ring opened formamidopyrimidine, Fapy.dG in Escherichia coli. Biochemistry. 46: 10202-12. PMID 17691820 DOI: 10.1021/Bi700628C  0.799
2007 Das A, Boldogh I, Lee JW, Harrigan JA, Hegde ML, Piotrowski J, de Souza Pinto N, Ramos W, Greenberg MM, Hazra TK, Mitra S, Bohr VA. The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1. The Journal of Biological Chemistry. 282: 26591-602. PMID 17611195 DOI: 10.1074/Jbc.M703343200  0.495
2007 Dhar S, Kodama T, Greenberg MM. Selective detection and quantification of oxidized abasic lesions in DNA. Journal of the American Chemical Society. 129: 8702-3. PMID 17592848 DOI: 10.1021/Ja073014E  0.75
2007 Xue L, Greenberg MM. Facile quantification of lesions derived from 2'-deoxyguanosine in DNA. Journal of the American Chemical Society. 129: 7010-1. PMID 17497789 DOI: 10.1021/Ja072174N  0.502
2007 Hong IS, Carter KN, Sato K, Greenberg MM. Characterization and mechanism of formation of tandem lesions in DNA by a nucleobase peroxyl radical. Journal of the American Chemical Society. 129: 4089-98. PMID 17335214 DOI: 10.1021/Ja0692276  0.482
2007 Ding H, Greenberg MM. Hole migration is the major pathway involved in alkali-labile lesion formation in DNA by the direct effect of ionizing radiation. Journal of the American Chemical Society. 129: 772-3. PMID 17243808 DOI: 10.1021/Ja0678931  0.436
2007 Greenberg MM. Elucidating DNA damage and repair processes by independently generating reactive and metastable intermediates. Organic & Biomolecular Chemistry. 5: 18-30. PMID 17164902 DOI: 10.1039/B612729K  0.495
2007 Xue L, Greenberg MM. Use of fluorescence sensors to determine that 2-deoxyribonolactone is the major alkali-labile deoxyribose lesion produced in oxidatively damaged DNA. Angewandte Chemie (International Ed. in English). 46: 561-4. PMID 17154191 DOI: 10.1002/Anie.200603454  0.441
2006 Imoto S, Patro JN, Jiang YL, Oka N, Greenberg MM. Synthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates. Journal of the American Chemical Society. 128: 14606-11. PMID 17090045 DOI: 10.1021/Ja065525R  0.817
2006 Kalam MA, Haraguchi K, Chandani S, Loechler EL, Moriya M, Greenberg MM, Basu AK. Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells. Nucleic Acids Research. 34: 2305-15. PMID 16679449 DOI: 10.1093/Nar/Gkl099  0.405
2006 Kroeger KM, Kim J, Goodman MF, Greenberg MM. Replication of an oxidized abasic site in Escherichia coli by a dNTP-stabilized misalignment mechanism that reads upstream and downstream nucleotides. Biochemistry. 45: 5048-56. PMID 16605273 DOI: 10.1021/Bi052276V  0.743
2006 Greenberg MM, Kreller CR, Young SE, Kim J. Reactivity of the C2'-oxidized abasic lesion and its relevance to interactions with type I base excision repair enzymes. Chemical Research in Toxicology. 19: 463-8. PMID 16544953 DOI: 10.1021/Tx060001Q  0.473
2006 Hong IS, Ding H, Greenberg MM. Radiosensitization by a modified nucleotide that produces DNA interstrand cross-links under hypoxic conditions. Journal of the American Chemical Society. 128: 2230-1. PMID 16478174 DOI: 10.1021/Ja058290C  0.505
2006 Hong IS, Ding H, Greenberg MM. Oxygen independent DNA interstrand cross-link formation by a nucleotide radical. Journal of the American Chemical Society. 128: 485-91. PMID 16402835 DOI: 10.1021/Ja0563657  0.424
2005 Greenberg MM. DNA interstrand cross-links from modified nucleotides: mechanism and application. Nucleic Acids Symposium Series (2004). 57-8. PMID 17150631 DOI: 10.1093/nass/49.1.57  0.423
2005 Kodama T, Greenberg MM. Preparation and analysis of oligonucleotides containing lesions resulting from C5'-oxidation. The Journal of Organic Chemistry. 70: 9916-24. PMID 16292822 DOI: 10.1021/Jo051666K  0.505
2005 Kim J, Kreller CR, Greenberg MM. Preparation and analysis of oligonucleotides containing the c4'-oxidized abasic site and related mechanistic probes. The Journal of Organic Chemistry. 70: 8122-9. PMID 16277338 DOI: 10.1021/Jo0512249  0.494
2005 Kow YW, Bao G, Minesinger B, Jinks-Robertson S, Siede W, Jiang YL, Greenberg MM. Mutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae. Nucleic Acids Research. 33: 6196-202. PMID 16257982 DOI: 10.1093/Nar/Gki926  0.433
2005 Hu J, de Souza-Pinto NC, Haraguchi K, Hogue BA, Jaruga P, Greenberg MM, Dizdaroglu M, Bohr VA. Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. The Journal of Biological Chemistry. 280: 40544-51. PMID 16221681 DOI: 10.1074/Jbc.M508772200  0.515
2005 Bales BC, Kodama T, Weledji YN, Pitié M, Meunier B, Greenberg MM. Mechanistic studies on DNA damage by minor groove binding copper-phenanthroline conjugates. Nucleic Acids Research. 33: 5371-9. PMID 16186134 DOI: 10.1093/Nar/Gki856  0.438
2005 Hong IS, Greenberg MM. DNA interstrand cross-link formation initiated by reaction between singlet oxygen and a modified nucleotide. Journal of the American Chemical Society. 127: 10510-1. PMID 16045337 DOI: 10.1021/Ja053493M  0.454
2005 Wiederholt CJ, Patro JN, Jiang YL, Haraguchi K, Greenberg MM. Excision of formamidopyrimidine lesions by endonucleases III and VIII is not a major DNA repair pathway in Escherichia coli. Nucleic Acids Research. 33: 3331-8. PMID 15944451 DOI: 10.1093/Nar/Gki655  0.829
2005 Oka N, Greenberg MM. The effect of the 2-amino group of 7,8-dihydro-8-oxo-2'-deoxyguanosine on translesion synthesis and duplex stability. Nucleic Acids Research. 33: 1637-43. PMID 15778433 DOI: 10.1093/Nar/Gki305  0.537
2005 Hong IS, Greenberg MM. Efficient DNA interstrand cross-link formation from a nucleotide radical. Journal of the American Chemical Society. 127: 3692-3. PMID 15771492 DOI: 10.1021/Ja042434Q  0.516
2005 Sato K, Greenberg MM. Selective detection of 2-deoxyribonolactone in DNA. Journal of the American Chemical Society. 127: 2806-7. PMID 15740088 DOI: 10.1021/Ja0426185  0.498
2005 Jiang YL, Wiederholt CJ, Patro JN, Haraguchi K, Greenberg MM. Synthesis of oligonucleotides containing Fapy.dG (N(6)-(2-deoxy-alpha,beta-D-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine) using a 5'-dimethoxytrityl dinucleotide phosphoramidite. The Journal of Organic Chemistry. 70: 141-9. PMID 15624916 DOI: 10.1021/Jo048253O  0.817
2004 Hong IS, Greenberg MM. Mild generation of 5-(2'-deoxyuridinyl)methyl radical from a phenyl selenide precursor. Organic Letters. 6: 5011-3. PMID 15606123 DOI: 10.1021/Ol047754T  0.303
2004 Greenberg MM, Weledji YN, Kroeger KM, Kim J. In vitro replication and repair of DNA containing a C2'-oxidized abasic site. Biochemistry. 43: 15217-22. PMID 15568814 DOI: 10.1021/Bi048360C  0.758
2004 Kroeger KM, Kim J, Goodman MF, Greenberg MM. Effects of the C4'-oxidized abasic site on replication in Escherichia coli. An unusually large deletion is induced by a small lesion. Biochemistry. 43: 13621-7. PMID 15504024 DOI: 10.1021/Bi048337R  0.772
2004 Patro JN, Haraguchi K, Delaney MO, Greenberg MM. Probing the configurations of formamidopyrimidine lesions Fapy.dA and Fapy.dG in DNA using endonuclease IV. Biochemistry. 43: 13397-403. PMID 15491146 DOI: 10.1021/Bi049035S  0.839
2004 Kroeger KM, Goodman MF, Greenberg MM. A comprehensive comparison of DNA replication past 2-deoxyribose and its tetrahydrofuran analog in Escherichia coli. Nucleic Acids Research. 32: 5480-5. PMID 15477395 DOI: 10.1093/Nar/Gkh873  0.712
2004 Hong IS, Carter KN, Greenberg MM. Evidence for glycosidic bond rotation in a nucleobase peroxyl radical and its effect on tandem lesion formation. The Journal of Organic Chemistry. 69: 6974-8. PMID 15471441 DOI: 10.1021/Jo0492158  0.529
2004 Kim J, Weledji YN, Greenberg MM. Independent generation and characterization of a C2'-oxidized abasic site in chemically synthesized oligonucleotides. The Journal of Organic Chemistry. 69: 6100-4. PMID 15373495 DOI: 10.1021/Jo049033D  0.514
2004 Greenberg MM, Weledji YN, Kim J, Bales BC. Repair of oxidized abasic sites by exonuclease III, endonuclease IV, and endonuclease III. Biochemistry. 43: 8178-83. PMID 15209514 DOI: 10.1021/Bi0496236  0.487
2004 Kroeger KM, Jiang YL, Kow YW, Goodman MF, Greenberg MM. Mutagenic effects of 2-deoxyribonolactone in Escherichia coli. An abasic lesion that disobeys the A-rule. Biochemistry. 43: 6723-33. PMID 15157106 DOI: 10.1021/Bi049813G  0.747
2004 Greenberg MM, Weledji YN, Kroeger KM, Kim J, Goodman MF. In vitro effects of a C4'-oxidized abasic site on DNA polymerases. Biochemistry. 43: 2656-63. PMID 14992603 DOI: 10.1021/Bi036028F  0.75
2004 Greenberg MM. In vitro and in vivo effects of oxidative damage to deoxyguanosine. Biochemical Society Transactions. 32: 46-50. PMID 14748710 DOI: 10.1042/Bst0320046  0.482
2003 Kim J, Gil JM, Greenberg MM. Synthesis and characterization of oligonucleotides containing the c4'-oxidized abasic site produced by bleomycin and other DNA damaging agents. Angewandte Chemie (International Ed. in English). 42: 5882-5. PMID 14673926 DOI: 10.1002/Anie.200352102  0.508
2003 Carter KN, Greenberg MM. Tandem lesions are the major products resulting from a pyrimidine nucleobase radical. Journal of the American Chemical Society. 125: 13376-8. PMID 14583031 DOI: 10.1021/Ja036629U  0.542
2003 Wiederholt CJ, Delaney MO, Pope MA, David SS, Greenberg MM. Repair of DNA containing Fapy·dG and its β-C-nucleoside analogue by formamidopyrimidine DNA glycosylase and MutY Biochemistry. 42: 9755-9760. PMID 12911318 DOI: 10.1021/Bi034844H  0.854
2003 Carter KN, Greenberg MM. Independent generation and study of 5,6-Dihydro-2'-deoxyuridin-6-yl, a member of the major family of reactive intermediates formed in DNA from the effects of gamma-radiolysis. The Journal of Organic Chemistry. 68: 4275-80. PMID 12762726 DOI: 10.1021/Jo034038G  0.444
2003 Hegedus LS, Greenberg MM, Wendling JJ, Bullock JP. Synthesis of 5,12-dioxocyclam nickel (II) complexes having quinoxaline substituents at the 6 and 13 positions as potential DNA bis-intercalating and cleaving agents. The Journal of Organic Chemistry. 68: 4179-88. PMID 12762716 DOI: 10.1021/Jo020708R  0.431
2003 Kroeger KM, Hashimoto M, Kow YW, Greenberg MM. Cross-linking of 2-deoxyribonolactone and its beta-elimination product by base excision repair enzymes. Biochemistry. 42: 2449-55. PMID 12600212 DOI: 10.1021/Bi027168C  0.748
2003 Xu YJ, DeMott MS, Hwang JT, Greenberg MM, Demple B. Action of human apurinic endonuclease (Ape1) on C1'-oxidized deoxyribose damage in DNA. Dna Repair. 2: 175-85. PMID 12531388 DOI: 10.1016/S1568-7864(02)00194-5  0.53
2002 Wiederholt CJ, Delaney MO, Greenberg MM. Interaction of DNA containing Fapy.dA or its C-nucleoside analogues with base excision repair enzymes. Implications for mutagenesis and enzyme inhibition. Biochemistry. 41: 15838-44. PMID 12501213 DOI: 10.1021/Bi025903E  0.828
2002 Delaney MO, Wiederholt CJ, Greenberg MM. Fapy.dA induces nucleotide misincorporation translesionally by a DNA polymerase. Angewandte Chemie (International Ed. in English). 41: 771-3. PMID 12491331 DOI: 10.1002/1521-3757(20020301)114:5<797::Aid-Ange797>3.0.Co;2-G  0.826
2002 Delaney MO, Greenberg MM. Synthesis of oligonucleotides and thermal stability of duplexes containing the beta-C-nucleoside analogue of Fapy*dG. Chemical Research in Toxicology. 15: 1460-5. PMID 12437337 DOI: 10.1021/Tx025588X  0.524
2002 Bales BC, Pitié M, Meunier B, Greenberg MM. A minor groove binding copper-phenanthroline conjugate produces direct strand breaks via beta-elimination of 2-deoxyribonolactone. Journal of the American Chemical Society. 124: 9062-3. PMID 12149005 DOI: 10.1021/Ja026970Z  0.503
2002 Wiederholt CJ, Greenberg MM. Fapy.dG instructs Klenow exo(-) to misincorporate deoxyadenosine. Journal of the American Chemical Society. 124: 7278-9. PMID 12071730 DOI: 10.1021/Ja026522R  0.819
2002 Haraguchi K, Delaney MO, Wiederholt CJ, Sambandam A, Hantosi Z, Greenberg MM. Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues. Journal of the American Chemical Society. 124: 3263-9. PMID 11916409 DOI: 10.1021/Ja012135Q  0.819
2002 Saparbaev M, Sidorkina OM, Jurado J, Privezentzev CV, Greenberg MM, Laval J. Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues. Environmental and Molecular Mutagenesis. 39: 10-7. PMID 11813291 DOI: 10.1002/Em.10041  0.388
2002 DeMott MS, Beyret E, Wong D, Bales BC, Hwang JT, Greenberg MM, Demple B. Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone. The Journal of Biological Chemistry. 277: 7637-40. PMID 11805079 DOI: 10.1074/Jbc.C100577200  0.566
2001 Greenberg MM. Attachment of reporter and conjugate groups to the 3' termini of oligonucleotides. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 4.5. PMID 18428852 DOI: 10.1002/0471142700.Nc0405S02  0.336
2001 Haraguchi K, Delaney MO, Wiederholt CJ, Sambandam A, Hantosi Z, Greenberg MM. Synthesis and characterization of oligonucleotides containing formamidopyrimidine lesions (Fapy.dA, Fapy.dG) at defined sites. Nucleic Acids Research. Supplement (2001). 129-30. PMID 12836298  0.798
2001 Greenberg MM, Hantosi Z, Wiederholt CJ, Rithner CD. Studies on N4-(2-deoxy-D-pentofuranosyl)-4,6-diamino-5-formamidopyrimidine (Fapy.dA) and N6-(2-deoxy-D-pentofuranosyl)-6-diamino-5-formamido-4-hydroxypyrimidine (Fapy.dG). Biochemistry. 40: 15856-61. PMID 11747463 DOI: 10.1021/Bi011490Q  0.83
2001 Greenberg MM, Kahl JD. Template-free segmental synthesis of oligonucleotides containing nonnative linkages. The Journal of Organic Chemistry. 66: 7151-4. PMID 11597244 DOI: 10.1021/Jo010610X  0.333
2001 Tallman KA, Greenberg MM. Oxygen-dependent DNA damage amplification involving 5,6-dihydrothymidin-5-yl in a structurally minimal system. Journal of the American Chemical Society. 123: 5181-7. PMID 11457379 DOI: 10.1021/Ja010180S  0.37
2001 Bales BC, Horner JH, Huang X, Newcomb M, Crich D, Greenberg MM. Product studies and laser flash photolysis on alkyl radicals containing two different beta-leaving groups are consonant with the formation of an olefin cation radical. Journal of the American Chemical Society. 123: 3623-9. PMID 11457093 DOI: 10.1021/Ja0042938  0.325
2001 Hashimoto M, Greenberg MM, Kow YW, Hwang JT, Cunningham RP. The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme endonuclease III. Journal of the American Chemical Society. 123: 3161-2. PMID 11457038 DOI: 10.1021/Ja003354Z  0.516
2001 Hwang JT, Greenberg MM. Synthesis of 2'-modified oligodeoxynucleotides via on-column conjugation. The Journal of Organic Chemistry. 66: 363-9. PMID 11429801 DOI: 10.1021/Jo000917G  0.347
2001 Zhu Q, Delaney MO, Greenberg MM. Observation and elimination of N-acetylation of oligonucleotides prepared using fast-deprotecting phosphoramidites and ultra-mild deprotection. Bioorganic & Medicinal Chemistry Letters. 11: 1105-7. PMID 11354354 DOI: 10.1016/S0960-894X(01)00161-5  0.322
2001 Privezentzev CV, Saparbaev M, Sambandam A, Greenberg MM, Laval J. AlkA protein is the third Escherichia coli DNA repair protein excising a ring fragmentation product of thymine. Biochemistry. 39: 14263-8. PMID 11087375 DOI: 10.1021/Bi001337G  0.495
2000 Carter KN, Taverner T, Schiesser CH, Greenberg MM. Chemical evidence for thiyl radical addition to the C6-position of a pyrimidine nucleoside and its possible relevance to DNA damage amplification Journal of Organic Chemistry. 65: 8375-8378. PMID 11101400 DOI: 10.1021/jo0007433  0.396
2000 Anderson AS, Hwang JT, Greenberg MM. Independent generation and reactivity of 2'-deoxy-5-methyleneuridin-5-yl, a significant reactive intermediate produced from thymidine as a result of oxidative stress Journal of Organic Chemistry. 65: 4648-4654. PMID 10959870 DOI: 10.1021/Jo000271S  0.412
2000 Hwang JT, Greenberg MM. Synthesis of modified oligodeoxyribonucleotides on a solid-phase support via derivatization of a selectively revealed 2'-amino-2'-deoxyuridine. Organic Letters. 1: 2021-4. PMID 10836059 DOI: 10.1021/Ol991196E  0.31
2000 Chen T, Cook GP, Koppisch AT, Greenberg MM. Investigation of the origin of the sequence selectivity for the 5-halo- 2'-deoxyuridine sensitization of DNA to damage by UV-irradiation Journal of the American Chemical Society. 122: 3861-3866. DOI: 10.1021/Ja994357I  0.456
1999 Fuchs T, Gates KS, Hwang JT, Greenberg MM. Photosensitization of guanine-specific DNA damage by a cyano-substituted quinoxaline di-N-oxide. Chemical Research in Toxicology. 12: 1190-4. PMID 10604868 DOI: 10.1021/Tx990149S  0.704
1999 Hwang JT, Greenberg MM, Fuchs T, Gates KS. Reaction of the hypoxia-selective antitumor agent tirapazamine with a C1'-radical in single-stranded and double-stranded DNA: the drug and its metabolites can serve as surrogates for molecular oxygen in radical-mediated DNA damage reactions. Biochemistry. 38: 14248-55. PMID 10571998 DOI: 10.1021/Bi991488N  0.701
1999 Hwang JT, Tallman KA, Greenberg MM. The reactivity of the 2-deoxyribonolactone lesion in single-stranded DNA and its implication in reaction mechanisms of DNA damage and repair. Nucleic Acids Research. 27: 3805-10. PMID 10481019 DOI: 10.1093/Nar/27.19.3805  0.553
1999 Sambandam A, Greenberg MM. The effects of 5R-5,6-dihydro-5-hydroxythymidine on duplex DNA stability and structure. Nucleic Acids Research. 27: 3597-602. PMID 10446252 DOI: 10.1093/Nar/27.17.3597  0.462
1999 Cook GP, Chen T, Koppisch AT, Greenberg MM. The effects of secondary structure and O2 on the formation of direct strand breaks upon UV irradiation of 5-bromodeoxyuridine-containing oligonucleotides Chemistry and Biology. 6: 451-459. PMID 10381405 DOI: 10.1016/S1074-5521(99)80063-5  0.493
1999 McMinn DL, Greenberg MM. Convergent solution-phase synthesis of a nucleopeptide using a protected oligonucleotide. Bioorganic & Medicinal Chemistry Letters. 9: 547-50. PMID 10098660 DOI: 10.1016/S0960-894X(99)00051-7  0.332
1999 Greenberg MM. Investigating nucleic acid damage processes via independent generation of reactive intermediates. Chemical Research in Toxicology. 11: 1235-48. PMID 9815182 DOI: 10.1021/Tx980174I  0.305
1999 Hwang J, Greenberg MM. Kinetics and Stereoselectivity of Thiol Trapping of Deoxyuridin-1‘-yl in Biopolymers and Their Relationship to the Formation of Premutagenic α-Deoxynucleotides Journal of the American Chemical Society. 121: 4311-4315. DOI: 10.1021/Ja990152Y  0.513
1999 Kahl JD, Greenberg MM. Introducing structural diversity in oligonycleotides via photolabile, convertible C5-substituted nucleotides Journal of the American Chemical Society. 121: 597-604. DOI: 10.1021/Ja983273R  0.381
1998 Daniels JS, Gates KS, Tronche C, Greenberg MM. Direct evidence for bimodal DNA damage induced by tirapazamine. Chemical Research in Toxicology. 11: 1254-7. PMID 9815184 DOI: 10.1021/Tx980184J  0.711
1998 Jurado J, Saparbaev M, Matray TJ, Greenberg MM, Laval J. The ring fragmentation product of thymidine C5-hydrate when present in DNA is repaired by the Escherichia coli Fpg and Nth proteins. Biochemistry. 37: 7757-63. PMID 9601036 DOI: 10.1021/Bi972982Z  0.481
1998 Chen T, Greenberg MM. Model Studies Indicate That Copper Phenanthroline Induces Direct Strand Breaks via β-Elimination of the 2‘-Deoxyribonolactone Intermediate Observed in Enediyne Mediated DNA Damage Journal of the American Chemical Society. 120: 3815-3816. DOI: 10.1021/Ja9800075  0.433
1998 McMinn DL, Greenberg MM. Postsynthetic Conjugation of Protected Oligonucleotides Containing 3‘-Alkylamines Journal of the American Chemical Society. 120: 3289-3294. DOI: 10.1021/Ja9740834  0.327
1998 Tallman KA, Tronche C, Yoo DJ, Greenberg MM. Release of superoxide from nucleoside peroxyl radicals, a double-edged sword? Journal of the American Chemical Society. 120: 4903-4909. DOI: 10.1021/Ja973200S  0.382
1998 Tronche C, Goodman BK, Greenberg MM. DNA damage induced via independent generation of the radical resulting from formal hydrogen atom abstraction from the C1′-position of a nucleotide Chemistry & Biology. 5: 263-271. DOI: 10.1016/S1074-5521(98)90619-6  0.551
1998 McMinn DL, Hirsch R, Greenberg MM. An orthogonal solid phase support for the synthesis of oligonucleotides containing 3′-phosphates and its application in the preparation of photolabile hybridization probes Tetrahedron Letters. 39: 4155-4158. DOI: 10.1016/S0040-4039(98)00773-4  0.321
1997 Greenberg MM, Matray TJ. Inhibition of klenow fragment (exo-) catalyzed DNA polymerization by (5R)-5,6-dihydro-5-hydroxythymidine and structural analogue 5,6-dihydro-5-methylthymidine. Biochemistry. 36: 14071-9. PMID 9369479 DOI: 10.1021/Bi971630P  0.424
1997 Matray TJ, Yoo DJ, McMinn DL, Greenberg MM. Synthesis of oligonucleotides containing 3'-alkylcarboxylic acids using a palladium labile oligonucleotide solid phase synthesis support. Bioconjugate Chemistry. 8: 99-102. PMID 9095347 DOI: 10.1021/Bc970013A  0.312
1997 Greenberg MM, Barvian MR, Cook GP, Goodman BK, Matray TJ, Tronche C, Venkatesan H. DNA Damage Induced via 5,6-Dihydrothymid-5-yl in Single-Stranded Oligonucleotides Journal of the American Chemical Society. 119: 1828-1839. DOI: 10.1021/Ja9533510  0.454
1997 McMinn DL, Greenberg MM. Synthesis of oligonucleotides containing 3'-alkyl amines using N-isobutyryl protected deoxyadenosine phosphoramidite Tetrahedron Letters. 38: 3123-3126. DOI: 10.1016/S0040-4039(97)00568-6  0.301
1996 Venkatesan H, Greenberg MM. Improved Utility of Photolabile Solid Phase Synthesis Supports for the Synthesis of Oligonucleotides Containing 3'-Hydroxyl Termini. The Journal of Organic Chemistry. 61: 525-529. PMID 11666970 DOI: 10.1021/Jo951550W  0.361
1996 Matray TJ, Haxton KJ, Greenberg MM. The effects of the ring fragmentation product of thymidine C5-hydrate on phosphodiesterases and klenow (exo-) fragment. Nucleic Acids Research. 23: 4642-8. PMID 8524655 DOI: 10.1093/Nar/23.22.4642  0.338
1996 Cook GP, Greenberg MM. A Novel Mechanism for the Formation of Direct Strand Breaks upon Anaerobic Photolysis of Duplex DNA Containing 5-Bromodeoxyuridine Journal of the American Chemical Society. 118: 10025-10030. DOI: 10.1021/Ja960652G  0.476
1996 McMinn DL, Greenberg MM. Novel solid phase synthesis supports for the preparation of oligonucleotides containing 3′-alkyl amines. Tetrahedron. 52: 3827-3840. DOI: 10.1016/S0040-4020(96)00053-1  0.312
1995 Barvian MR, Greenberg MM. Independent Generation of 5,6-Dihydrothymid-5-yl in Single-Stranded Polythymidylate. O2 Is Necessary for Strand Scission Journal of the American Chemical Society. 117: 8291-8292. DOI: 10.1021/Ja00136A036  0.343
1995 Greenberg MM. Photochemical release of protected oligonucleotides containing 3′-glycolate termini Tetrahedron. 51: 29-38. DOI: 10.1016/0040-4020(94)00946-R  0.308
1994 Cook GP, Greenberg MM. A General Synthesis of C2'-Deuterated Ribonucleosides The Journal of Organic Chemistry. 59: 4704-4706. DOI: 10.1021/Jo00095A060  0.312
1994 Greenberg MM, Gilmore JL. Cleavage of Oligonucleotides from Solid-Phase Supports Using o-Nitrobenzyl Photochemistry The Journal of Organic Chemistry. 59: 746-753. DOI: 10.1021/Jo00083A014  0.308
1991 Greenberg MM, Blackstock SC, Berson JA, Merrill RA, Duchamp JC, Zilm KW. Structure of the carrier of the cross-polarization magic angle spinning carbon-13 nuclear magnetic resonance signal assigned to 3,4-dimethylenethiophene. Multiple position-labeling and chemical trapping in annealed glasses Journal of the American Chemical Society. 113: 2318-2319. DOI: 10.1021/Ja00006A069  0.718
1989 Greenberg MM, Blackstock SC, Stone KJ, Berson JA. Ground-state multiplicities of 3,4-dimethylenefuran and 3,4-dimethylenethiophene. Experimental tests of ab initio and semiempirical theories of heteroatom-bridged disjoint biradicals Journal of the American Chemical Society. 111: 3671-3679. DOI: 10.1021/Ja00192A026  0.711
1989 Stone KJ, Greenberg MM, Blackstock SC, Berson JA. Heterocyclic aromatic non-kekulé molecules. Synthesis and solution-phase chemistry of the singlet biradicals 3,4-dimethylenefuran and 3,4-dimethylenethiophene Journal of the American Chemical Society. 111: 3659-3671. DOI: 10.1021/Ja00192A025  0.726
1989 Zilm KW, Merrill RA, Webb GG, Greenberg MM, Berson JA. Two-dimensional solid-state NMR of a captive intermediate: Structure of the radical centers in 3,4-dimethylenethiophene Journal of the American Chemical Society. 111: 1533-1535. DOI: 10.1021/Ja00186A077  0.596
1987 Zilm KW, Merrill RA, Greenberg MM, Berson JA. The first magic angle spinning NMR spectrum of a captive intermediate: Direct observation of a singlet ground state biradical, 3,4-dimethylenefuran Journal of the American Chemical Society. 109: 1567-1569. DOI: 10.1021/Ja00239A046  0.577
1987 Greenberg MM, Blackstock SC, Berson JA. Identity of 3,4-dimethylenethiophene reactive intermediates from diazene and bis-allene precursors. Correlation of singlet biradical reactivity in the tetramethyleneethane and trimethylenemethane series. Tetrahedron Letters. 28: 4263-4266. DOI: 10.1016/S0040-4039(00)96480-3  0.752
1986 Stone KJ, Greenberg MM, Goodman JL, Peters KS, Berson JA. 3,4-Dimethylenefuran and 3,4-dimethylenethiophene, heterocyclic analogues of the disjoint non-Kekulé hydrocarbon tetramethyleneethane Journal of the American Chemical Society. 108: 8088-8089. DOI: 10.1021/Ja00285A035  0.584
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