Theresa Guise - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Biochemistry, Molecular Biology

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Trivedi T, Manaa M, John S, Reiken S, Murthy S, Pagnotti GM, Dole NS, She Y, Suresh S, Hain BA, Regan J, Ofer R, Wright L, Robling A, Cao X, ... ... Guise TA, et al. Zoledronic acid improves bone quality and muscle function in a high bone turnover state. Biorxiv : the Preprint Server For Biology. PMID 37333318 DOI: 10.1101/2023.06.01.543305  0.365
2022 Ballinger TJ, Thompson WR, Guise TA. The bone-muscle connection in breast cancer: implications and therapeutic strategies to preserve musculoskeletal health. Breast Cancer Research : Bcr. 24: 84. PMID 36419084 DOI: 10.1186/s13058-022-01576-2  0.435
2022 Liu H, He J, Bagheri-Yarmand R, Li Z, Liu R, Wang Z, Bach DH, Huang YH, Lin P, Guise TA, Gagel RF, Yang J. Osteocyte CIITA aggravates osteolytic bone lesions in myeloma. Nature Communications. 13: 3684. PMID 35760800 DOI: 10.1038/s41467-022-31356-7  0.439
2022 Arellano DL, Juárez P, Verdugo-Meza A, Almeida-Luna PS, Corral-Avila JA, Drescher F, Olvera F, Jiménez S, Elzey BD, Guise TA, Fournier PG. Bone microenvironment-suppressed T cells increase osteoclast formation and osteolytic bone metastases in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 35635377 DOI: 10.1002/jbmr.4615  0.453
2021 Trivedi T, Pagnotti GM, Guise TA, Mohammad KS. The Role of TGF-β in Bone Metastases. Biomolecules. 11. PMID 34827641 DOI: 10.3390/biom11111643  0.456
2021 Trivedi T, Guise TA. Systemic effects of abnormal bone resorption on muscle, metabolism, and cognition. Bone. 154: 116245. PMID 34718221 DOI: 10.1016/j.bone.2021.116245  0.446
2020 Coleman RE, Croucher PI, Padhani AR, Clézardin P, Chow E, Fallon M, Guise T, Colangeli S, Capanna R, Costa L. Bone metastases. Nature Reviews. Disease Primers. 6: 83. PMID 33060614 DOI: 10.1038/s41572-020-00216-3  0.457
2020 Hussain A, Tripathi A, Pieczonka C, Cope D, McNatty A, Logothetis C, Guise T. Bone health effects of androgen-deprivation therapy and androgen receptor inhibitors in patients with nonmetastatic castration-resistant prostate cancer. Prostate Cancer and Prostatic Diseases. PMID 33028943 DOI: 10.1038/s41391-020-00296-y  0.364
2020 Seth P, Xu W, Yang Y, Hu Z, Head M, Mangold KA, Sullivan M, Wang CH, Saha P, Gulukota K, Helseth DL, Guise T, Prabhakar BS, Kaul K, Schreiber H. LyP-1-modified oncolytic adenoviruses targeting transforming growth factor β inhibit tumor growth and metastases and augment immune checkpoint inhibitor therapy in breast cancer mouse models. Human Gene Therapy. PMID 32394753 DOI: 10.1089/Hum.2020.078  0.466
2020 Ballinger T, El-Azab S, Liu Z, Guise T, Imel E. Abstract P2-08-11: High prevalence and incidence of new onset diabetes in metastatic breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P2-08-11  0.459
2019 Morris MJ, Corey E, Guise TA, Gulley JL, Kevin Kelly W, Quinn DI, Scholz A, Sgouros G. Radium-223 mechanism of action: implications for use in treatment combinations. Nature Reviews. Urology. PMID 31712765 DOI: 10.1038/S41585-019-0251-X  0.364
2019 Saito H, Gasser A, Bolamperti S, Maeda M, Matthies L, Jähn K, Long CL, Schlüter H, Kwiatkowski M, Saini V, Pajevic PD, Bellido T, van Wijnen AJ, Mohammad KS, Guise TA, et al. TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone. Nature Communications. 10: 1354. PMID 30902975 DOI: 10.1038/S41467-019-08778-X  0.442
2019 Waning DL, Guise TA, Mohammad KS. A "Connexin" Responsible for the Fatal Attraction of Cancer to Bone. Cell Metabolism. 29: 6-8. PMID 30625309 DOI: 10.1016/J.Cmet.2018.12.014  0.475
2018 Wright L, Mohammad K, Guise T. Abstract 1808: The anti-estrogen endoxifen altered bone morphology and reduced muscle function in mice Cancer Research. 78: 1808-1808. DOI: 10.1158/1538-7445.Am2018-1808  0.515
2017 Mohammad KS, Guise TA. Breaking Down Barriers to Chemoresistance: Role of Chemotherapy-Induced Osteoblastic Jagged1. Cancer Cell. 32: 717-718. PMID 29232546 DOI: 10.1016/j.ccell.2017.11.016  0.483
2017 Juárez P, Fournier PGJ, Mohammad KS, McKenna RC, Davis HW, Peng XH, Niewolna M, Mauviel A, Chirgwin JM, Guise TA. Halofuginone inhibits TGF-β/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis. Oncotarget. 8: 86447-86462. PMID 29156807 DOI: 10.18632/oncotarget.21200  0.47
2017 Esposito M, Guise T, Kang Y. The Biology of Bone Metastasis. Cold Spring Harbor Perspectives in Medicine. PMID 29101110 DOI: 10.1101/Cshperspect.A031252  0.577
2017 Ross MH, Esser AK, Fox GC, Schmieder AH, Yang X, Hu G, Pan D, Su X, Xu Y, Novack DV, Walsh T, Colditz GA, Lukaszewicz GH, Cordell E, Novack JS, ... ... Guise TA, et al. Bone-induced expression of integrin β3 enables targeted nanotherapy of breast cancer metastases. Cancer Research. PMID 28855208 DOI: 10.1158/0008-5472.Can-17-1225  0.547
2017 Trivedi T, Zheng Y, Fournier PGJ, Murthy S, John S, Schillo S, Dunstan CR, Mohammad KS, Zhou H, Seibel MJ, Guise TA. The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm. Oncotarget. 8: 26687-26701. PMID 28460457 DOI: 10.18632/oncotarget.15803  0.348
2017 Regan JN, Trivedi T, Guise TA, Waning DL. The Role of TGFβ in Bone-Muscle Crosstalk. Current Osteoporosis Reports. PMID 28161871 DOI: 10.1007/S11914-017-0344-5  0.348
2016 Bonetto A, Kays JK, Parker VA, Matthews RR, Barreto R, Puppa MJ, Kang KS, Carson JA, Guise TA, Mohammad KS, Robling AG, Couch ME, Koniaris LG, Zimmers TA. Differential Bone Loss in Mouse Models of Colon Cancer Cachexia. Frontiers in Physiology. 7: 679. PMID 28123369 DOI: 10.3389/fphys.2016.00679  0.458
2016 Wright LE, Harhash AA, Kozlow WM, Waning DL, Regan JN, She Y, John SK, Murthy S, Niewolna M, Marks AR, Mohammad KS, Guise TA. Aromatase inhibitor-induced bone loss increases the progression of estrogen receptor-negative breast cancer in bone and exacerbates muscle weakness in vivo. Oncotarget. PMID 28039445 DOI: 10.18632/Oncotarget.14139  0.474
2016 Zhang P, Xing C, Rhodes SD, He Y, Deng K, Li Z, He F, Zhu C, Nguyen L, Zhou Y, Chen S, Mohammad KS, Guise TA, Abdel-Wahab O, Xu M, et al. Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice. Stem Cell Reports. PMID 27237378 DOI: 10.1016/J.Stemcr.2016.04.013  0.326
2016 Teramachi J, Nagata Y, Mohammad K, Inagaki Y, Ohata Y, Guise T, Michou L, Brown JP, Windle JJ, Kurihara N, Roodman GD. Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease. The Journal of Clinical Investigation. PMID 26878170 DOI: 10.1172/Jci82012  0.405
2016 Wright L, Harhash A, Waning D, Mohammad K, Marks A, Guise T. Bisphosphonates prevent osteolysis and muscle weakness in aromatase inhibitor-treated mice with breast cancer bone metastases Bone Abstracts. DOI: 10.1530/Boneabs.5.Cabs.Oc4.2  0.515
2016 Regan J, Waning D, Mohammad K, Mikesell C, Reiken S, Marks A, Guise T. Muscle dysfunction in immune competent mice with osteolytic breast cancer in bone is associated with skeletal muscle oxidation of RyR1 Bone Abstracts. DOI: 10.1530/Boneabs.5.Cabs.Oc4.1  0.413
2016 Xu W, Yang Y, Neill T, Wang H, Wang C, Yun C, Guise T, Brendler CB, Iozzo RV, Wang L, Seth P. 417. Intratumoral Delivery of Oncolytic Adenovirus Expressing Decorin Inhibits Growth and Metastases of 4T1 Breast Tumors in Syngeneic Immune Competent BALB/c Mice Model Molecular Therapy. 24: S165-S166. DOI: 10.1016/S1525-0016(16)33226-9  0.444
2015 Regan JN, Waning DL, Guise TA. Skeletal muscle Ca(2+) mishandling: another effect of bone-to-muscle signaling. Seminars in Cell & Developmental Biology. PMID 26593325 DOI: 10.1016/J.Semcdb.2015.11.007  0.337
2015 Yang Y, Xu WW, Neill T, Hu Z, Wang CH, Xiao X, Stock S, Guise T, Yun CO, Brendler CB, Iozzo RV, Seth P. Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases. Human Gene Therapy. PMID 26467629 DOI: 10.1089/Hum.2015.098  0.532
2015 Waning DL, Mohammad KS, Reiken S, Xie W, Andersson DC, John S, Chiechi A, Wright LE, Umanskaya A, Niewolna M, Trivedi T, Charkhzarrin S, Khatiwada P, Wronska A, Haynes A, ... ... Guise TA, et al. Excess TGF-β mediates muscle weakness associated with bone metastases in mice. Nature Medicine. PMID 26457758 DOI: 10.1038/Nm.3961  0.399
2015 Stayrook KR, Mack JK, Cerabona D, Edwards DF, Bui HH, Niewolna M, Fournier PG, Mohammad KS, Waning DL, Guise TA. TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis. Bonekey Reports. 4: 719. PMID 26157579 DOI: 10.1038/Bonekey.2015.88  0.519
2015 Wu C, Rankin EB, Castellini L, Alcudia JF, LaGory EL, Andersen R, Rhodes SD, Wilson TL, Mohammad KS, Castillo AB, Guise TA, Schipani E, Giaccia AJ. Corrigendum: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin. Genes & Development. 29: 1202. PMID 26063577  0.32
2015 Waning DL, Guise TA. Cancer-associated muscle weakness: What's bone got to do with it? Bonekey Reports. 4: 691. PMID 25992285 DOI: 10.1038/Bonekey.2015.59  0.404
2015 Fournier PG, Juárez P, Jiang G, Clines GA, Niewolna M, Kim HS, Walton HW, Peng XH, Liu Y, Mohammad KS, Wells CD, Chirgwin JM, Guise TA. The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone. Cancer Cell. 27: 809-21. PMID 25982816 DOI: 10.1016/J.Ccell.2015.04.009  0.43
2015 Wu C, Rankin EB, Castellini L, Fernandez-Alcudia J, LaGory EL, Andersen R, Rhodes SD, Wilson TL, Mohammad KS, Castillo AB, Guise TA, Schipani E, Giaccia AJ. Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin. Genes & Development. 29: 817-31. PMID 25846796 DOI: 10.1101/Gad.255000.114  0.409
2015 Wright LE, Buijs JT, Kim HS, Coats LE, Scheidler AM, John SK, She Y, Murthy S, Ma N, Chin-Sinex HJ, Bellido TM, Bateman TA, Mendonca MS, Mohammad KS, Guise TA. Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Model. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 1268-79. PMID 25588731 DOI: 10.1002/Jbmr.2458  0.431
2015 Buijs JT, Matula KM, Cheung H, Kruithof-de Julio M, van der Mark MH, Snoeks TJ, Cohen R, Corver WE, Mohammad KS, Jonkers J, Guise TA, van der Pluijm G. Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase. The Journal of Pathology. 235: 745-59. PMID 25421310 DOI: 10.1002/path.4488  0.401
2014 Siclari VA, Mohammad KS, Tompkins DR, Davis H, McKenna CR, Peng X, Wessner LL, Niewolna M, Guise TA, Suvannasankha A, Chirgwin JM. Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis. Breast Cancer Research : Bcr. 16: 458. PMID 25439669 DOI: 10.1186/S13058-014-0458-Y  0.464
2014 Wright LE, Guise TA. The microenvironment matters: estrogen deficiency fuels cancer bone metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2817-9. PMID 24803577 DOI: 10.1158/1078-0432.CCR-14-0576  0.524
2014 Xu W, Zhang Z, Yang Y, Hu Z, Wang CH, Morgan M, Wu Y, Hutten R, Xiao X, Stock S, Guise T, Prabhakar BS, Brendler C, Seth P. Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1504-17. PMID 24791939 DOI: 10.1038/Mt.2014.80  0.462
2014 Waning DL, Guise TA. Molecular mechanisms of bone metastasis and associated muscle weakness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3071-7. PMID 24677373 DOI: 10.1158/1078-0432.Ccr-13-1590  0.518
2014 Xu W, Zhang Z, Guise T, Brendler CB, Seth P. Abstract 723: Liver-detargeted Ad5/48 chimaeric hexon based oncolytic adenovirus targeting TGFβ signaling: A safe and effective approach for the treatment of prostate cancer bone metastases Cancer Research. 74: 723-723. DOI: 10.1158/1538-7445.Am2014-723  0.438
2013 Chiechi A, Waning DL, Stayrook KR, Buijs JT, Guise TA, Mohammad KS. Role of TGF-β in breast cancer bone metastases. Advances in Bioscience and Biotechnology (Print). 4: 15-30. PMID 24558636 DOI: 10.4236/Abb.2013.410A4003  0.522
2013 Waning DL, Mohammad KS, Guise TA. Cancer-associated osteoclast differentiation takes a good look in the miR(NA)ror. Cancer Cell. 24: 407-9. PMID 24135278 DOI: 10.1016/J.Ccr.2013.10.001  0.446
2013 Guise TA. Breast cancer bone metastases: it's all about the neighborhood. Cell. 154: 957-9. PMID 23993088 DOI: 10.1016/j.cell.2013.08.020  0.455
2013 Rhodes SD, Wu X, He Y, Chen S, Yang H, Staser KW, Wang J, Zhang P, Jiang C, Yokota H, Dong R, Peng X, Yang X, Murthy S, Azhar M, ... ... Guise TA, et al. Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2476-89. PMID 23703870 DOI: 10.1002/Jbmr.1992  0.328
2013 Casimiro S, Mohammad KS, Pires R, Tato-Costa J, Alho I, Teixeira R, Carvalho A, Ribeiro S, Lipton A, Guise TA, Costa L. RANKL/RANK/MMP-1 molecular triad contributes to the metastatic phenotype of breast and prostate cancer cells in vitro. Plos One. 8: e63153. PMID 23696795 DOI: 10.1371/journal.pone.0063153  0.494
2013 Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, ... ... Guise TA, et al. Differential stem- and progenitor-cell trafficking by prostaglandin E2. Nature. 495: 365-9. PMID 23485965 DOI: 10.1038/Nature11929  0.319
2013 Wright LE, Frye JB, Lukefahr AL, Timmermann BN, Mohammad KS, Guise TA, Funk JL. Curcuminoids block TGF-β signaling in human breast cancer cells and limit osteolysis in a murine model of breast cancer bone metastasis. Journal of Natural Products. 76: 316-21. PMID 23145932 DOI: 10.1021/Np300663V  0.537
2013 Bilezikian JP, Bouillon R, Clemens T, Compston J, Bauer DC, Ebeling PR, Engelke K, Goltzman D, Guise T, Beur SMJD, Jüppner H, Lyons K, McCauley L, McClung MR, Miller PD, et al. Primer on the metabolic bone diseases and disorders of mineral metabolism. Journal of Bone and Joint Surgery-British Volume. 1087-1087. DOI: 10.1002/9781119266594  0.357
2012 Buijs JT, Stayrook KR, Guise TA. The role of TGF-β in bone metastasis: novel therapeutic perspectives. Bonekey Reports. 1: 96. PMID 23951484 DOI: 10.1038/bonekey.2012.96  0.474
2012 Juárez P, Mohammad KS, Yin JJ, Fournier PG, McKenna RC, Davis HW, Peng XH, Niewolna M, Javelaud D, Chirgwin JM, Mauviel A, Guise TA. Halofuginone inhibits the establishment and progression of melanoma bone metastases. Cancer Research. 72: 6247-56. PMID 23002206 DOI: 10.1158/0008-5472.CAN-12-1444  0.457
2012 Hu Z, Gupta J, Zhang Z, Gerseny H, Berg A, Chen YJ, Zhang Z, Du H, Brendler CB, Xiao X, Pienta KJ, Guise T, Lee C, Stern PH, Stock S, et al. Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model. Human Gene Therapy. 23: 871-82. PMID 22551458 DOI: 10.1089/Hum.2012.040  0.489
2012 Pollari S, Käkönen RS, Mohammad KS, Rissanen JP, Halleen JM, Wärri A, Nissinen L, Pihlavisto M, Marjamäki A, Perälä M, Guise TA, Kallioniemi O, Käkönen SM. Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis. Molecular Cancer Research : McR. 10: 597-604. PMID 22522458 DOI: 10.1158/1541-7786.MCR-11-0482  0.519
2012 Nickerson NK, Mohammad KS, Gilmore JL, Crismore E, Bruzzaniti A, Guise TA, Foley J. Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat pad. Plos One. 7: e30255. PMID 22276166 DOI: 10.1371/journal.pone.0030255  0.489
2012 Cao L, Shao M, Schilder J, Guise T, Mohammad KS, Matei D. Tissue transglutaminase links TGF-β, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer. Oncogene. 31: 2521-34. PMID 21963846 DOI: 10.1038/Onc.2011.429  0.392
2012 Rhodes SD, He Y, Chen S, Yang H, Menon KM, Staser K, Yang X, Mohammad KS, Guise T, Xu M, Yang F. Haploinsufficiency of Nf1 in Myeloid Lineages Contributes to Neurofibromatosis Type 1 Associated Skeletal Deficits Blood. 120: 830-830. DOI: 10.1182/Blood.V120.21.830.830  0.453
2012 Pollari S, Käkönen SM, Edgren H, Wolf M, Kohonen P, Sara H, Guise T, Nees M, Kallioniemi O. Erratum to: Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis Breast Cancer Research and Treatment. 131: 1085-1086. DOI: 10.1007/S10549-011-1654-4  0.527
2011 Buijs JT, Stayrook KR, Guise TA. TGF-β in the Bone Microenvironment: Role in Breast Cancer Metastases. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 4: 261-81. PMID 21748439 DOI: 10.1007/s12307-011-0075-6  0.531
2011 Clines GA, Mohammad KS, Grunda JM, Clines KL, Niewolna M, McKenna CR, McKibbin CR, Yanagisawa M, Suva LJ, Chirgwin JM, Guise TA. Regulation of postnatal trabecular bone formation by the osteoblast endothelin A receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2523-36. PMID 21698666 DOI: 10.1002/jbmr.450  0.382
2011 Buijs JT, Juárez P, Guise TA. Therapeutic strategies to target TGF-β in the treatment of bone metastases. Current Pharmaceutical Biotechnology. 12: 2121-37. PMID 21619539  0.485
2011 Weilbaecher KN, Guise TA, McCauley LK. Cancer to bone: a fatal attraction. Nature Reviews. Cancer. 11: 411-25. PMID 21593787 DOI: 10.1038/Nrc3055  0.468
2011 Liang H, Ma SY, Mohammad K, Guise TA, Balian G, Shen FH. The reaction of bone to tumor growth from human breast cancer cells in a rat spine single metastasis model. Spine. 36: 497-504. PMID 21422981 DOI: 10.1097/BRS.0b013e3181d8906f  0.396
2011 Hadji P, Aapro MS, Body JJ, Bundred NJ, Brufsky A, Coleman RE, Gnant M, Guise T, Lipton A. Management of aromatase inhibitor-associated bone loss in postmenopausal women with breast cancer: practical guidance for prevention and treatment. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 22: 2546-55. PMID 21415233 DOI: 10.1093/Annonc/Mdr017  0.509
2011 Edwards BJ, Raisch DW, Shankaran V, McKoy JM, Gradishar W, Bunta AD, Samaras AT, Boyle SN, Bennett CL, West DP, Guise TA. Cancer therapy associated bone loss: implications for hip fractures in mid-life women with breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 560-8. PMID 21288927 DOI: 10.1158/1078-0432.CCR-10-1595  0.38
2011 Mohammad KS, Javelaud D, Fournier PG, Niewolna M, McKenna CR, Peng XH, Duong V, Dunn LK, Mauviel A, Guise TA. TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases. Cancer Research. 71: 175-84. PMID 21084275 DOI: 10.1158/0008-5472.Can-10-2651  0.676
2011 Juárez P, Guise TA. TGF-β in cancer and bone: implications for treatment of bone metastases. Bone. 48: 23-9. PMID 20699127 DOI: 10.1016/j.bone.2010.08.004  0.523
2011 Pollari S, Käkönen SM, Edgren H, Wolf M, Kohonen P, Sara H, Guise T, Nees M, Kallioniemi O. Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis. Breast Cancer Research and Treatment. 125: 421-30. PMID 20352489 DOI: 10.1007/S10549-010-0848-5  0.561
2011 Hoggatt J, Mohammad KS, Chitteti BR, Singh P, Speth JM, Hu P, Poteat B, Srour E, Guise T, Pelus LM. Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms Blood. 118: 724-724. DOI: 10.1182/Blood.V118.21.724.724  0.384
2011 Pollari S, Käkönen R, Mohammad KS, Rissanen JP, Halleen J, Wärri A, Nissinen L, Pihlavisto M, Marjamäki A, Perälä M, Guise T, Kallioniemi O, Käkönen S. Abstract 845: Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis Cancer Research. 71: 845-845. DOI: 10.1158/1538-7445.Am2011-845  0.569
2011 Guise T. New therapies for cancer-induced bone disease: Preclinical perspective Bone. 48. DOI: 10.1016/J.Bone.2010.10.026  0.487
2010 Guise T. Examining the metastatic niche: targeting the microenvironment. Seminars in Oncology. 37: S2-14. PMID 21111245 DOI: 10.1053/J.Seminoncol.2010.10.007  0.563
2010 Guise TA, Brufsky A, Coleman RE. Understanding and optimizing bone health in breast cancer. Current Medical Research and Opinion. 26: 3-20. PMID 21050131 DOI: 10.1185/03007995.2010.533162  0.486
2010 Hu Z, Zhang Z, Guise T, Seth P. Systemic delivery of an oncolytic adenovirus expressing soluble transforming growth factor-β receptor II-Fc fusion protein can inhibit breast cancer bone metastasis in a mouse model. Human Gene Therapy. 21: 1623-9. PMID 20712434 DOI: 10.1089/Hum.2010.018  0.443
2010 Coenegrachts L, Maes C, Torrekens S, Van Looveren R, Mazzone M, Guise TA, Bouillon R, Stassen JM, Carmeliet P, Carmeliet G. Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation. Cancer Research. 70: 6537-47. PMID 20682798 DOI: 10.1158/0008-5472.CAN-09-4092  0.491
2010 Coleman RE, Lipton A, Roodman GD, Guise TA, Boyce BF, Brufsky AM, Clézardin P, Croucher PI, Gralow JR, Hadji P, Holen I, Mundy GR, Smith MR, Suva LJ. Metastasis and bone loss: advancing treatment and prevention. Cancer Treatment Reviews. 36: 615-20. PMID 20478658 DOI: 10.1016/J.Ctrv.2010.04.003  0.472
2010 Juárez P, Guise TA. Tgf-Beta pathway as a therapeutic target in bone metastases. Current Pharmaceutical Design. 16: 1301-12. PMID 20166977  0.463
2010 Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB. Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene. 29: 811-21. PMID 19915614 DOI: 10.1038/Onc.2009.389  0.507
2009 Guise TA. Breaking down bone: new insight into site-specific mechanisms of breast cancer osteolysis mediated by metalloproteinases. Genes & Development. 23: 2117-23. PMID 19759260 DOI: 10.1101/gad.1854909  0.525
2009 Dunn LK, Mohammad KS, Fournier PG, McKenna CR, Davis HW, Niewolna M, Peng XH, Chirgwin JM, Guise TA. Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment. Plos One. 4: e6896. PMID 19727403 DOI: 10.1371/Journal.Pone.0006896  0.696
2009 Mohammad KS, Fournier PG, Guise TA, Chirgwin JM. Agents targeting prostate cancer bone metastasis. Anti-Cancer Agents in Medicinal Chemistry. 9: 1079-88. PMID 19719455 DOI: 10.2174/187152009789735008  0.463
2009 Casimiro S, Guise TA, Chirgwin J. The critical role of the bone microenvironment in cancer metastases. Molecular and Cellular Endocrinology. 310: 71-81. PMID 19616059 DOI: 10.1016/J.Mce.2009.07.004  0.497
2009 Mohammad KS, Chen CG, Balooch G, Stebbins E, McKenna CR, Davis H, Niewolna M, Peng XH, Nguyen DH, Ionova-Martin SS, Bracey JW, Hogue WR, Wong DH, Ritchie RO, Suva LJ, ... ... Guise TA, et al. Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone. Plos One. 4: e5275. PMID 19357790 DOI: 10.1371/Journal.Pone.0005275  0.442
2009 Brown SA, Guise TA. Cancer treatment-related bone disease. Critical Reviews in Eukaryotic Gene Expression. 19: 47-60. PMID 19191756  0.483
2009 Casimiro S, Alho I, Fernandes A, Lipton A, Guise T, Costa L. RANKL plays a role in migration and invasion of the bone-seeking cell line MDA-MB-231-BO2 through human type I collagen by up-regulating MMP1. Cancer Research. 69: 2052. DOI: 10.1158/0008-5472.Sabcs-2052  0.506
2008 Coleman RE, Guise TA, Lipton A, Roodman GD, Berenson JR, Body JJ, Boyce BF, Calvi LM, Hadji P, McCloskey EV, Saad F, Smith MR, Suva LJ, Taichman RS, Vessella RL, et al. Advancing treatment for metastatic bone cancer: consensus recommendations from the Second Cambridge Conference. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6387-95. PMID 18927277 DOI: 10.1158/1078-0432.Ccr-08-1572  0.458
2008 Guise TA. Antitumor effects of bisphosphonates: promising preclinical evidence. Cancer Treatment Reviews. 34: S19-24. PMID 18486348 DOI: 10.1016/j.ctrv.2008.03.006  0.437
2008 Mohammad KS, Chirgwin JM, Guise TA. Assessing new bone formation in neonatal calvarial organ cultures. Methods in Molecular Biology (Clifton, N.J.). 455: 37-50. PMID 18463809 DOI: 10.1007/978-1-59745-104-8_3  0.38
2008 Hadji P, Body JJ, Aapro MS, Brufsky A, Coleman RE, Guise T, Lipton A, Tubiana-Hulin M. Practical guidance for the management of aromatase inhibitor-associated bone loss Annals of Oncology. 19: 1407-1416. PMID 18448451 DOI: 10.1093/Annonc/Mdn164  0.388
2008 Clines GA, Guise TA. Molecular mechanisms and treatment of bone metastasis. Expert Reviews in Molecular Medicine. 10: e7. PMID 18321396 DOI: 10.1017/S1462399408000616  0.5
2008 Akhtari M, Mansuri J, Newman KA, Guise TM, Seth P. Biology of breast cancer bone metastasis. Cancer Biology & Therapy. 7: 3-9. PMID 18059174 DOI: 10.4161/cbt.7.1.5163  0.507
2008 Mohammad K, Stebbins E, Kingsley L, Fournier P, Niewolna M, McKenna C, Peng X, Higgins L, Wong D, Guise T. P48. Transforming growth factor β receptor I kinase inhibitor and bisphosphonates are additive to reduce breast cancer bone metastases Cancer Treatment Reviews. 34: 37-38. DOI: 10.1016/J.Ctrv.2008.03.106  0.507
2008 Casimiro S, Alho I, Fernandes A, Lipton A, Guise T, Costa L. P38. RANKL plays a role in migration and invasion of the bone-seeking cell line MDA-MB-231-BO2 and regulates MMP1 and MMP9 expression Cancer Treatment Reviews. 34: 27-28. DOI: 10.1016/J.Ctrv.2008.03.080  0.376
2008 Fournier P, Clines G, Chirgwin J, Guise T. P32. Transforming growth factor-β (TGF-β) promotes prostate cancer bone metastases: Increased expression of pro-osteolytic genes and of PMEPA1, a new TGF-β signalling regulator Cancer Treatment Reviews. 34: 25. DOI: 10.1016/J.Ctrv.2008.03.074  0.415
2008 Kingsley L, Fournier P, Chirgwin J, Guise T. P16. Hypoxia and breast cancer bone metastasis: HIF-1α enhances TGF-β signaling and expression of prometastatic factors CXCR4 and VEGF Cancer Treatment Reviews. 34: 18. DOI: 10.1016/J.Ctrv.2008.03.058  0.394
2007 Brown SA, Clines GA, Guise TA. Local effects of malignancy on bone. Current Opinion in Endocrinology, Diabetes, and Obesity. 14: 436-41. PMID 17982348 DOI: 10.1097/MED.0b013e3282f15419  0.485
2007 Kingsley LA, Fournier PG, Chirgwin JM, Guise TA. Molecular biology of bone metastasis. Molecular Cancer Therapeutics. 6: 2609-17. PMID 17938257 DOI: 10.1158/1535-7163.MCT-07-0234  0.474
2007 Brown SA, Guise TA. Cancer-associated bone disease. Current Osteoporosis Reports. 5: 120-7. PMID 17925193  0.472
2007 Chirgwin JM, Guise TA. Skeletal metastases: decreasing tumor burden by targeting the bone microenvironment. Journal of Cellular Biochemistry. 102: 1333-42. PMID 17907152 DOI: 10.1002/jcb.21556  0.462
2007 Fournier PG, Guise TA. BMP7: a new bone metastases prevention? The American Journal of Pathology. 171: 739-43. PMID 17690188 DOI: 10.2353/ajpath.2007.070582  0.42
2007 Kingsley LA, Chirgwin JM, Guise TA. Breaking new ground to build bone. Proceedings of the National Academy of Sciences of the United States of America. 104: 10753-4. PMID 17581868 DOI: 10.1073/pnas.0704357104  0.355
2007 Javelaud D, Mohammad KS, McKenna CR, Fournier P, Luciani F, Niewolna M, André J, Delmas V, Larue L, Guise TA, Mauviel A. Stable overexpression of Smad7 in human melanoma cells impairs bone metastasis. Cancer Research. 67: 2317-24. PMID 17332363 DOI: 10.1158/0008-5472.Can-06-3950  0.475
2007 Clines GA, Mohammad KS, Bao Y, Stephens OW, Suva LJ, Shaughnessy JD, Fox JW, Chirgwin JM, Guise TA. Dickkopf homolog 1 mediates endothelin-1-stimulated new bone formation. Molecular Endocrinology (Baltimore, Md.). 21: 486-98. PMID 17068196 DOI: 10.1210/me.2006-0346  0.389
2007 Bartholin L, Wessner LL, Chirgwin JM, Guise TA. The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells. Cancer Letters. 246: 230-6. PMID 16616811 DOI: 10.1016/j.canlet.2006.02.019  0.446
2007 Aapro MS, Hadji P, Brufsky A, Tubiana-Hulin M, Guise T, Body JJ. 2007 POSTER Recommendations for the prevention of aromatase inhibitor-associated bone loss in women with breast cancer Ejc Supplements. 5: 186. DOI: 10.1016/S1359-6349(07)70769-3  0.487
2007 Ma S(, Choi L, McKenna C, Mohammad K, Li X, Guise T, Shen F. 89. Metastatic Spine Disease: An Isolated Spine Tumor Model with Human Breast Cancer Cells The Spine Journal. 7: 43S-44S. DOI: 10.1016/J.Spinee.2007.07.107  0.418
2006 Guise TA. Bone loss and fracture risk associated with cancer therapy. The Oncologist. 11: 1121-31. PMID 17110632 DOI: 10.1634/theoncologist.11-10-1121  0.393
2006 Guise TA, Mohammad KS, Clines G, Stebbins EG, Wong DH, Higgins LS, Vessella R, Corey E, Padalecki S, Suva L, Chirgwin JM. Basic mechanisms responsible for osteolytic and osteoblastic bone metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6213s-6216s. PMID 17062703 DOI: 10.1158/1078-0432.Ccr-06-1007  0.46
2006 Lipton A, Berenson JR, Body JJ, Boyce BF, Bruland OS, Carducci MA, Cleeland CS, Clohisy DR, Coleman RE, Cook RJ, Guise TA, Pearse RN, Powles TJ, Rogers MJ, Roodman GD, et al. Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6209s-6212s. PMID 17062702 DOI: 10.1158/1078-0432.Ccr-06-1213  0.474
2006 Seth P, Wang ZG, Pister A, Zafar MB, Kim S, Guise T, Wakefield L. Development of oncolytic adenovirus armed with a fusion of soluble transforming growth factor-beta receptor II and human immunoglobulin Fc for breast cancer therapy. Human Gene Therapy. 17: 1152-60. PMID 17032151 DOI: 10.1089/Hum.2006.17.1152  0.433
2006 Guise TA. Do markers of bone turnover predict clinical outcome in patients with bone metastases? Nature Clinical Practice. Endocrinology & Metabolism. 2: 258-9. PMID 16932296 DOI: 10.1038/ncpendmet0171  0.376
2006 Fournier PG, Chirgwin JM, Guise TA. New insights into the role of T cells in the vicious cycle of bone metastases. Current Opinion in Rheumatology. 18: 396-404. PMID 16763461 DOI: 10.1097/01.bor.0000231909.35043.da  0.466
2006 Theriault RL, Biermann JS, Brown E, Brufsky A, Demers L, Grewal RK, Guise T, Jackson R, McEnery K, Podoloff D, Ravdin P, Shapiro CL, Smith M, Van Poznak CH. NCCN Task Force Report: Bone Health and Cancer Care. Journal of the National Comprehensive Cancer Network : Jnccn. 4: S1-20; quiz S21-2. PMID 16737674  0.425
2006 Chirgwin JM, Guise TA. Does prostate-specific antigen contribute to bone metastases? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1395-7. PMID 16533760 DOI: 10.1158/1078-0432.CCR-06-0005  0.3
2005 Bendre MS, Margulies AG, Walser B, Akel NS, Bhattacharrya S, Skinner RA, Swain F, Ramani V, Mohammad KS, Wessner LL, Martinez A, Guise TA, Chirgwin JM, Gaddy D, Suva LJ. Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway. Cancer Research. 65: 11001-9. PMID 16322249 DOI: 10.1158/0008-5472.Can-05-2630  0.324
2005 Titus B, Frierson HF, Conaway M, Ching K, Guise T, Chirgwin J, Hampton G, Theodorescu D. Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2. Cancer Research. 65: 7320-7. PMID 16103083 DOI: 10.1158/0008-5472.Can-05-1403  0.357
2005 Kozlow W, Guise TA. Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy. Journal of Mammary Gland Biology and Neoplasia. 10: 169-80. PMID 16025223 DOI: 10.1007/s10911-005-5399-8  0.528
2005 Guise TA, Kozlow WM, Heras-Herzig A, Padalecki SS, Yin JJ, Chirgwin JM. Molecular mechanisms of breast cancer metastases to bone. Clinical Breast Cancer. 5: S46-53. PMID 15807924  0.529
2005 Aris RM, Guise TA. Cystic fibrosis and bone disease: are we missing a genetic link? The European Respiratory Journal. 25: 9-11. PMID 15640316 DOI: 10.1183/09031936.04.00125804  0.435
2005 Aris RM, Merkel PA, Bachrach LK, Borowitz DS, Boyle MP, Elkin SL, Guise TA, Hardin DS, Haworth CS, Holick MF, Joseph PM, O'Brien K, Tullis E, Watts NB, White TB. Guide to bone health and disease in cystic fibrosis. The Journal of Clinical Endocrinology and Metabolism. 90: 1888-96. PMID 15613415 DOI: 10.1210/Jc.2004-1629  0.36
2005 Titus B, Chirgwin J, Guise T, Hampton G, Theodorescu D. 595: The Metastasis Suppressor Gene RhoGDI2 Reduceslung Metastasis in Human Bladder Cancer Via Downregulation of Endothelin 1 Journal of Urology. 173: 163-163. DOI: 10.1016/S0022-5347(18)34835-3  0.346
2004 Costa L, Fernandes A, Oliveira AG, Leitzel K, Ali S, Schaller J, Demers L, Guise T, Lipton A. Parathyroid hormone-related protein (PTHrp) expression in human bone metastases (BM). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 9696. PMID 28016071 DOI: 10.1200/Jco.2004.22.14_Suppl.9696  0.474
2004 Clines GA, Guise TA. Mechanisms and treatment for bone metastases. Clinical Advances in Hematology & Oncology : H&O. 2: 295-302. PMID 16163196  0.516
2004 Guise TA, Mohammad KS. Endothelins in bone cancer metastases. Cancer Treatment and Research. 118: 197-212. PMID 15043194  0.474
2003 Padalecki SS, Weldon KS, Reveles XT, Buller CL, Grubbs B, Cui Y, Yin JJ, Hall DC, Hummer BT, Weissman BE, Dallas M, Guise TA, Leach RJ, Johnson-Pais TL. Chromosome 18 suppresses prostate cancer metastases. Urologic Oncology. 21: 366-73. PMID 14670546 DOI: 10.1016/S1078-1439(03)00013-9  0.354
2003 O'Keefe RJ, Guise TA. Molecular mechanisms of bone metastasis and therapeutic implications. Clinical Orthopaedics and Related Research. S100-4. PMID 14600598 DOI: 10.1097/01.Blo.0000093847.72468.2F  0.396
2003 Mohammad KS, Guise TA. Mechanisms of osteoblastic metastases: role of endothelin-1. Clinical Orthopaedics and Related Research. S67-74. PMID 14600594 DOI: 10.1097/01.blo.0000093047.96273.4e  0.52
2003 Guise TA, Chirgwin JM. Transforming growth factor-beta in osteolytic breast cancer bone metastases. Clinical Orthopaedics and Related Research. S32-8. PMID 14600590 DOI: 10.1097/01.blo.0000093055.96273.69  0.497
2003 Guise TA, Chirgwin JM. Role of bisphosphonates in prostate cancer bone metastases. Seminars in Oncology. 30: 717-23. PMID 14571419  0.409
2003 Yin JJ, Mohammad KS, Käkönen SM, Harris S, Wu-Wong JR, Wessale JL, Padley RJ, Garrett IR, Chirgwin JM, Guise TA. A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases. Proceedings of the National Academy of Sciences of the United States of America. 100: 10954-9. PMID 12941866 DOI: 10.1073/Pnas.1830978100  0.522
2003 Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordón-Cardo C, Guise TA, Massagué J. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 3: 537-49. PMID 12842083 DOI: 10.1016/S1535-6108(03)00132-6  0.455
2003 Guise TA, Yin JJ, Mohammad KS. Role of endothelin-1 in osteoblastic bone metastases. Cancer. 97: 779-84. PMID 12548575 DOI: 10.1002/cncr.11129  0.454
2002 Gallwitz WE, Guise TA, Mundy GR. Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo. The Journal of Clinical Investigation. 110: 1559-72. PMID 12438453 DOI: 10.1172/JCI11936  0.409
2002 Wysolmerski JJ, Dann PR, Zelazny E, Dunbar ME, Insogna KL, Guise TA, Perkins AS. Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1164-70. PMID 12096830 DOI: 10.1359/jbmr.2002.17.7.1164  0.495
2002 Guise T, Yin JJ, Thomas RJ, Dallas M, Cui Y, Gillespie MT. Parathyroid hormone-related protein (PTHrP)-(1-139) isoform is efficiently secreted in vitro and enhances breast cancer metastasis to bone in vivo Bone. 30: 670-676. PMID 11996903 DOI: 10.1016/S8756-3282(02)00685-3  0.5
2001 Padalecki SS, Guise TA. Actions of bisphosphonates in animal models of breast cancer. Breast Cancer Research : Bcr. 4: 35-41. PMID 11879558 DOI: 10.1186/bcr415  0.515
1999 Lemieux P, Harvey J, Guise T, Dallas M, Oesterreich S, Yin JJ, Selander K, Fuqua S. Low cell motility induced by hsp27 overexpression decreases osteolytic bone metastases of human breast cancer cells in vivo. Journal of Bone and Mineral Research. 14: 1570-1575. PMID 10469286 DOI: 10.1359/Jbmr.1999.14.9.1570  0.587
1998 Mundy GR, Guise T. Role of parathyroid hormone-related peptide in hypercalcemia of malignancy and osteolytic bone disease Endocrine-Related Cancer. 5: 15-26. DOI: 10.1677/Erc.0.0050015  0.566
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