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Jack D. Keene - Publications

Duke University, Durham, NC 

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ruthig VA, Yokonishi T, Friedersdorf MB, Batchvarova S, Hardy J, Garness JA, Keene JD, Capel B. A transgenic DND1GFP fusion allele reports in vivo expression and RNA binding targets in undifferentiated mouse germ cells. Biology of Reproduction. PMID 33394034 DOI: 10.1093/biolre/ioaa233  1
2019 Ruthig VA, Friedersdorf MB, Garness JA, Munger SC, Bunce C, Keene JD, Capel B. The RNA-binding protein DND1 acts Sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming. Development (Cambridge, England). PMID 31253634 DOI: 10.1242/dev.175950  1
2018 Bisogno LS, Friedersdorf MB, Keene JD. Ras Post-transcriptionally Enhances a Pre-malignantly Primed EMT to Promote Invasion. Iscience. 4: 97-108. PMID 30240757 DOI: 10.1016/j.isci.2018.05.011  1
2018 Bisogno LS, Keene JD. RNA regulons in cancer and inflammation. Current Opinion in Genetics & Development. 48: 97-103. PMID 29175729 DOI: 10.1016/j.gde.2017.11.004  0.92
2017 Bisogno LS, Keene JD. Analysis of post-transcriptional regulation during cancer progression using a donor-derived isogenic model of tumorigenesis. Methods (San Diego, Calif.). PMID 28529064 DOI: 10.1016/j.ymeth.2017.05.012  0.92
2016 Nicholson CO, Friedersdorf MB, Bisogno LS, Keene JD. DO-RIP-seq to quantify RNA binding sites transcriptome-wide. Methods (San Diego, Calif.). PMID 27840290 DOI: 10.1016/j.ymeth.2016.11.004  1
2016 Nicholson CO, Friedersdorf MB, Keene JD. Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq. Rna (New York, N.Y.). PMID 27742911 DOI: 10.1261/rna.058115.116  1
2016 Smola MJ, Christy TW, Inoue K, Nicholson CO, Friedersdorf M, Keene JD, Lee DM, Calabrese JM, Weeks KM. SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27578869 DOI: 10.1073/pnas.1600008113  0.76
2015 Blackinton JG, Keene JD. Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation. Nucleic Acids Research. PMID 26490963 DOI: 10.1093/nar/gkv1066  0.4
2015 Moon SL, Blackinton JG, Anderson JR, Dozier MK, Dodd BJ, Keene JD, Wilusz CJ, Bradrick SS, Wilusz J. XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability. Plos Pathogens. 11: e1004708. PMID 25747802 DOI: 10.1371/journal.ppat.1004708  1
2014 Payne TL, Blackinton J, Frisbee A, Pickeral J, Sawant S, Vandergrift NA, Freel SA, Ferrari G, Keene JD, Tomaras GD. Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. Journal of Virology. 88: 9514-28. PMID 24899193 DOI: 10.1128/JVI.00802-14  1
2014 Blackinton JG, Keene JD. Post-transcriptional RNA regulons affecting cell cycle and proliferation. Seminars in Cell & Developmental Biology. 34: 44-54. PMID 24882724 DOI: 10.1016/j.semcdb.2014.05.014  1
2014 Friedersdorf MB, Keene JD. Advancing the functional utility of PAR-CLIP by quantifying background binding to mRNAs and lncRNAs. Genome Biology. 15: R2. PMID 24393468 DOI: 10.1186/gb-2014-15-1-r2  1
2014 Keene JD. The globalization of messenger RNA regulation National Science Review. 1: 184-186. DOI: 10.1093/nsr/nwu004  1
2013 Simone LE, Keene JD. Mechanisms coordinating ELAV/Hu mRNA regulons. Current Opinion in Genetics & Development. 23: 35-43. PMID 23312841 DOI: 10.1016/j.gde.2012.12.006  1
2013 Keene JD. Preface Advances in Experimental Medicine and Biology. 768: v-vi. DOI: 10.1007/978-1-4614-5107_5  1
2012 Mansfield KD, Keene JD. Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation. Nucleic Acids Research. 40: 2734-46. PMID 22139917 DOI: 10.1093/nar/gkr1114  1
2011 Corcoran DL, Georgiev S, Mukherjee N, Gottwein E, Skalsky RL, Keene JD, Ohler U. PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data. Genome Biology. 12: R79. PMID 21851591 DOI: 10.1186/gb-2011-12-8-r79  1
2011 Mukherjee N, Corcoran DL, Nusbaum JD, Reid DW, Georgiev S, Hafner M, Ascano M, Tuschl T, Ohler U, Keene JD. Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability. Molecular Cell. 43: 327-39. PMID 21723170 DOI: 10.1016/j.molcel.2011.06.007  1
2011 Mazan-Mamczarz K, Hagner PR, Zhang Y, Dai B, Lehrmann E, Becker KG, Keene JD, Gorospe M, Liu Z, Gartenhaus RB. ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes. Blood. 117: 2441-50. PMID 21209379 DOI: 10.1182/blood-2010-09-310987  1
2010 Morris AR, Mukherjee N, Keene JD. Systematic analysis of posttranscriptional gene expression. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 162-80. PMID 20836020 DOI: 10.1002/wsbm.54  1
2010 Neplioueva V, Dobrikova EY, Mukherjee N, Keene JD, Gromeier M. Tissue type-specific expression of the dsRNA-binding protein 76 and genome-wide elucidation of its target mRNAs. Plos One. 5: e11710. PMID 20668518 DOI: 10.1371/journal.pone.0011710  1
2010 Keene JD. The global dynamics of RNA stability orchestrates responses to cellular activation. Bmc Biology. 8: 95. PMID 20619007 DOI: 10.1186/1741-7007-8-95  1
2010 Keene JD. Minireview: global regulation and dynamics of ribonucleic Acid. Endocrinology. 151: 1391-7. PMID 20332203 DOI: 10.1210/en.2009-1250  1
2009 Mukherjee N, Lager PJ, Friedersdorf MB, Thompson MA, Keene JD. Coordinated posttranscriptional mRNA population dynamics during T-cell activation. Molecular Systems Biology. 5: 288. PMID 19638969 DOI: 10.1038/msb.2009.44  1
2009 Papadaki O, Milatos S, Grammenoudi S, Mukherjee N, Keene JD, Kontoyiannis DL. Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR. Journal of Immunology (Baltimore, Md. : 1950). 182: 6779-88. PMID 19454673 DOI: 10.4049/jimmunol.0900377  1
2009 Mansfield KD, Keene JD. The ribonome: a dominant force in co-ordinating gene expression. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 101: 169-81. PMID 19152504 DOI: 10.1042/BC20080055  1
2009 Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD. Proteomic and immunologic analyses of brain tumor exosomes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1541-57. PMID 19109410 DOI: 10.1096/fj.08-122184  1
2008 Tiruchinapalli DM, Caron MG, Keene JD. Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. Journal of Neurochemistry. 107: 1529-43. PMID 19014379 DOI: 10.1111/j.1471-4159.2008.05718.x  1
2008 Tiruchinapalli DM, Ehlers MD, Keene JD. Activity-dependent expression of RNA binding protein HuD and its association with mRNAs in neurons. Rna Biology. 5: 157-68. PMID 18769135  1
2008 Mazan-Mamczarz K, Hagner PR, Corl S, Srikantan S, Wood WH, Becker KG, Gorospe M, Keene JD, Levenson AS, Gartenhaus RB. Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype. Oncogene. 27: 6151-63. PMID 18641687 DOI: 10.1038/onc.2008.215  1
2008 Morris AR, Mukherjee N, Keene JD. Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets. Molecular and Cellular Biology. 28: 4093-103. PMID 18411299 DOI: 10.1128/MCB.00155-08  1
2008 Beach DL, Keene JD. Ribotrap : targeted purification of RNA-specific RNPs from cell lysates through immunoaffinity precipitation to identify regulatory proteins and RNAs. Methods in Molecular Biology (Clifton, N.J.). 419: 69-91. PMID 18369976 DOI: 10.1007/978-1-59745-033-1_5  1
2008 Pyhtila B, Zheng T, Lager PJ, Keene JD, Reedy MC, Nicchitta CV. Signal sequence- and translation-independent mRNA localization to the endoplasmic reticulum. Rna (New York, N.Y.). 14: 445-53. PMID 18192611 DOI: 10.1261/rna.721108  1
2008 Mazroui R, Di Marco S, Clair E, von Roretz C, Tenenbaum SA, Keene JD, Saleh M, Gallouzi IE. Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis. The Journal of Cell Biology. 180: 113-27. PMID 18180367 DOI: 10.1083/jcb.200709030  1
2007 Keene JD. Biological clocks and the coordination theory of RNA operons and regulons. Cold Spring Harbor Symposia On Quantitative Biology. 72: 157-65. PMID 18419273 DOI: 10.1101/sqb.2007.72.013  1
2007 Konopka JL, Penalva LO, Thompson JM, White LJ, Beard CW, Keene JD, Johnston RE. A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo. Plos Pathogens. 3: e199. PMID 18215114 DOI: 10.1371/journal.ppat.0030199  1
2007 Keene JD. RNA regulons: coordination of post-transcriptional events. Nature Reviews. Genetics. 8: 533-43. PMID 17572691 DOI: 10.1038/nrg2111  1
2006 Keene JD, Komisarow JM, Friedersdorf MB. RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nature Protocols. 1: 302-7. PMID 17406249 DOI: 10.1038/nprot.2006.47  1
2005 Stephens SB, Dodd RD, Brewer JW, Lager PJ, Keene JD, Nicchitta CV. Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation. Molecular Biology of the Cell. 16: 5819-31. PMID 16221886 DOI: 10.1091/mbc.E05-07-0685  1
2005 Keene JD, Lager PJ. Post-transcriptional operons and regulons co-ordinating gene expression. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 13: 327-37. PMID 15868425 DOI: 10.1007/s10577-005-0848-1  1
2004 Mesarovic MD, Sreenath SN, Keene JD. Search for organising principles: understanding in systems biology. Systems Biology. 1: 19-27. PMID 17052112 DOI: 10.1049/sb:20045010  1
2004 Penalva LO, Keene JD. Biotinylated tags for recovery and characterization of ribonucleoprotein complexes. Biotechniques. 37: 604, 606, 608-10. PMID 15517973  1
2004 Penalva LO, Burdick MD, Lin SM, Sutterluety H, Keene JD. RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells. Molecular Cancer. 3: 24. PMID 15353001 DOI: 10.1186/1476-4598-3-24  1
2004 Kenan DJ, Keene JD. La gets its wings. Nature Structural & Molecular Biology. 11: 303-5. PMID 15048103 DOI: 10.1038/nsmb0404-303  1
2004 Penalva LO, Tenenbaum SA, Keene JD. Gene expression analysis of messenger RNP complexes. Methods in Molecular Biology (Clifton, N.J.). 257: 125-34. PMID 14770002 DOI: 10.1385/1-59259-750-5:125  1
2004 Keene JD. Microbiology and Molecular Biology Reviews: Note from the editor in chief Microbiology and Molecular Biology Reviews. 68: i.  1
2003 Keene JD. Posttranscriptional generation of macromolecular complexes. Molecular Cell. 12: 1347-9. PMID 14690589 DOI: 10.1016/S1097-2765(03)00496-9  1
2003 Intine RV, Tenenbaum SA, Sakulich AL, Keene JD, Maraia RJ. Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs. Molecular Cell. 12: 1301-7. PMID 14636586 DOI: 10.1016/S1097-2765(03)00429-5  1
2003 Tenenbaum SA, Carson CC, Atasoy U, Keene JD. Genome-wide regulatory analysis using en masse nuclear run-ons and ribonomic profiling with autoimmune sera. Gene. 317: 79-87. PMID 14604794 DOI: 10.1016/S0378-1119(03)00661-9  1
2003 Lerner RS, Seiser RM, Zheng T, Lager PJ, Reedy MC, Keene JD, Nicchitta CV. Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes. Rna (New York, N.Y.). 9: 1123-37. PMID 12923260 DOI: 10.1261/rna.5610403  1
2003 Mazan-Mamczarz K, Galbán S, López de Silanes I, Martindale JL, Atasoy U, Keene JD, Gorospe M. RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proceedings of the National Academy of Sciences of the United States of America. 100: 8354-9. PMID 12821781 DOI: 10.1073/pnas.1432104100  1
2003 Keene JD. Organizing mRNA export. Nature Genetics. 33: 111-2. PMID 12560814 DOI: 10.1038/ng0203-111  1
2002 Lipes BD, Keene JD. Autoimmune epitopes in messenger RNA. Rna (New York, N.Y.). 8: 762-71. PMID 12088149 DOI: 10.1017/S1355838202021507  1
2002 Keene JD, Tenenbaum SA. Eukaryotic mRNPs may represent posttranscriptional operons. Molecular Cell. 9: 1161-7. PMID 12086614 DOI: 10.1016/S1097-2765(02)00559-2  1
2002 Tenenbaum SA, Lager PJ, Carson CC, Keene JD. Ribonomics: identifying mRNA subsets in mRNP complexes using antibodies to RNA-binding proteins and genomic arrays. Methods (San Diego, Calif.). 26: 191-8. PMID 12054896 DOI: 10.1016/S1046-2023(02)00022-1  1
2002 Eystathioy T, Chan EK, Tenenbaum SA, Keene JD, Griffith K, Fritzler MJ. A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Molecular Biology of the Cell. 13: 1338-51. PMID 11950943 DOI: 10.1091/mbc.01-11-0544  1
2001 Brown V, Jin P, Ceman S, Darnell JC, O'Donnell WT, Tenenbaum SA, Jin X, Feng Y, Wilkinson KD, Keene JD, Darnell RB, Warren ST. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell. 107: 477-87. PMID 11719188 DOI: 10.1016/S0092-8674(01)00568-2  1
2001 Keene JD. Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. Proceedings of the National Academy of Sciences of the United States of America. 98: 7018-24. PMID 11416181 DOI: 10.1073/pnas.111145598  1
2000 Tenenbaum SA, Carson CC, Lager PJ, Keene JD. Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays. Proceedings of the National Academy of Sciences of the United States of America. 97: 14085-90. PMID 11121017 DOI: 10.1073/pnas.97.26.14085  1
2000 Ali N, Pruijn GJ, Kenan DJ, Keene JD, Siddiqui A. Human La antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation. The Journal of Biological Chemistry. 275: 27531-40. PMID 10856291 DOI: 10.1074/jbc.M001487200  1
2000 Nagai Y, Tucker T, Ren H, Kenan DJ, Henderson BS, Keene JD, Strittmatter WJ, Burke JR. Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening. The Journal of Biological Chemistry. 275: 10437-42. PMID 10744733 DOI: 10.1074/jbc.275.14.10437  1
1999 Andrews LG, Keene JD. Identification of specific protein-RNA target sites using libraries of natural sequences. Methods in Molecular Biology (Clifton, N.J.). 118: 233-44. PMID 10549526 DOI: 10.1385/1-59259-676-2:233  1
1999 Kenan DJ, Keene JD. In vitro selection of aptamers from RNA libraries. Methods in Molecular Biology (Clifton, N.J.). 118: 217-31. PMID 10549525 DOI: 10.1385/1-59259-676-2:217  1
1999 Antic D, Lu N, Keene JD. ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells. Genes & Development. 13: 449-61. PMID 10049360  1
1999 Ford LP, Watson J, Keene JD, Wilusz J. ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes & Development. 13: 188-201. PMID 9925643  1
1999 Keene JD. Why is Hu where? Shuttling of early-response-gene messenger RNA subsets. Proceedings of the National Academy of Sciences of the United States of America. 96: 5-7. PMID 9874760 DOI: 10.1073/pnas.96.1.5  1
1998 Atasoy U, Watson J, Patel D, Keene JD. ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. Journal of Cell Science. 111: 3145-56. PMID 9763509  1
1998 Antic D, Keene JD. Messenger ribonucleoprotein complexes containing human ELAV proteins: interactions with cytoskeleton and translational apparatus. Journal of Cell Science. 111: 183-97. PMID 9405302  1
1997 Antic D, Keene JD. Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression. American Journal of Human Genetics. 61: 273-8. PMID 9311730 DOI: 10.1086/514866  1
1997 Jain RG, Andrews LG, McGowan KM, Pekala PH, Keene JD. Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. Molecular and Cellular Biology. 17: 954-62. PMID 9001249  1
1996 Keene JD. RNA recognition by autoantigens and autoantibodies. Molecular Biology Reports. 23: 173-81. PMID 9112226  1
1996 Gao FB, Keene JD. Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation. Journal of Cell Science. 109: 579-89. PMID 8907704  1
1996 Methot N, Pickett G, Keene JD, Sonenberg N. In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: the role of the RNA remotif. Rna (New York, N.Y.). 2: 38-50. PMID 8846295  1
1996 Keene JD. RNA surfaces as functional mimetics of proteins. Chemistry & Biology. 3: 505-13. PMID 8807880 DOI: 10.1016/S1074-5521(96)90139-8  1
1996 Keene JD. Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies. Methods in Enzymology. 267: 367-83. PMID 8743327  1
1996 Das S, Kenan DJ, Bocskai D, Keene JD, Dasgupta A. Sequences within a small yeast RNA required for inhibition of internal initiation of translation: interaction with La and other cellular proteins influences its inhibitory activity. Journal of Virology. 70: 1624-32. PMID 8627683  1
1996 Keene JD. Letters Scientist. 10.  1
1995 Jain RG, Andrews LG, McGowan KM, Gao F, Keene JD, Pekala PP. Hel-N1, an RNA-binding protein, is a ligand for an A + U rich region of the GLUT1 3' UTR. Nucleic Acids Symposium Series. 209-11. PMID 8643372  1
1995 Chang YN, Kenan DJ, Keene JD, Gatignol A, Jeang KT. Direct interactions between autoantigen La and human immunodeficiency virus leader RNA. Journal of Virology. 69: 618-9. PMID 7983768  0.6
1995 Romac JM, Keene JD. Overexpression of the arginine-rich carboxy-terminal region of U1 snRNP 70K inhibits both splicing and nucleocytoplasmic transport of mRNA. Genes & Development. 9: 1400-10. PMID 7797079  1
1994 Kenan DJ, Tsai DE, Keene JD. Exploring molecular diversity with combinatorial shape libraries. Trends in Biochemical Sciences. 19: 57-64. PMID 8160266 DOI: 10.1016/0968-0004(94)90033-7  1
1994 King PH, Levine TD, Fremeau RT, Keene JD. Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1943-52. PMID 8158249  1
1994 Maraia RJ, Kenan DJ, Keene JD. Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III. Molecular and Cellular Biology. 14: 2147-58. PMID 8114745  1
1994 Gao FB, Carson CC, Levine T, Keene JD. Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1. Proceedings of the National Academy of Sciences of the United States of America. 91: 11207-11. PMID 7972035  1
1994 Chang YN, Kenan DJ, Keene JD, Gatignol A, Jeang KT. Direct interactions between autoantigen La and human immunodeficiency virus leader RNA. Journal of Virology. 68: 7008-20. PMID 7933083  1
1994 Romac JM, Graff DH, Keene JD. The U1 small nuclear ribonucleoprotein (snRNP) 70K protein is transported independently of U1 snRNP particles via a nuclear localization signal in the RNA-binding domain. Molecular and Cellular Biology. 14: 4662-70. PMID 7516470  1
1994 Kelekar A, Saitta MR, Keene JD. Molecular composition of Ro small ribonucleoprotein complexes in human cells. Intracellular localization of the 60- and 52-kD proteins. The Journal of Clinical Investigation. 93: 1637-44. PMID 7512986 DOI: 10.1172/JCI117145  1
1994 Saitta MR, Arnett FC, Keene JD. 60-kDa Ro protein autoepitopes identified using recombinant polypeptides. Journal of Immunology (Baltimore, Md. : 1950). 152: 4192-202. PMID 7511672  1
1993 Levine TD, Gao F, King PH, Andrews LG, Keene JD. Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs. Molecular and Cellular Biology. 13: 3494-504. PMID 8497264  1
1993 Meerovitch K, Svitkin YV, Lee HS, Lejbkowicz F, Kenan DJ, Chan EK, Agol VI, Keene JD, Sonenberg N. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. Journal of Virology. 67: 3798-807. PMID 8389906  1
1993 Tsai DE, Keene JD. In vitro selection of RNA epitopes using autoimmune patient serum. Journal of Immunology (Baltimore, Md. : 1950). 150: 1137-45. PMID 7678618  1
1992 Saitta MR, Keene JD. Molecular biology of nuclear autoantigens. Rheumatic Diseases Clinics of North America. 18: 283-310. PMID 1626070  1
1992 Harper DS, Fresco LD, Keene JD. RNA binding specificity of a Drosophila snRNP protein that shares sequence homology with mammalian U1-A and U2-B" proteins. Nucleic Acids Research. 20: 3645-50. PMID 1386424 DOI: 10.1093/nar/20.14.3645  1
1992 Tsai DE, Kenan DJ, Keene JD. In vitro selection of an RNA epitope immunologically cross-reactive with a peptide. Proceedings of the National Academy of Sciences of the United States of America. 89: 8864-8. PMID 1384035  1
1991 St Clair EW, Kenan D, Burch JA, Keene JD, Pisetsky DS. Anti-La antibody production by MRL-1pr/1pr mice. Analysis of fine specificity. Journal of Immunology (Baltimore, Md. : 1950). 146: 1885-92. PMID 2005384  1
1991 Tamura H, Kohchi C, Yamada R, Ikeda T, Koiwai O, Patterson E, Keene JD, Okada K, Kjeldsen E, Nishikawa K. Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites. Nucleic Acids Research. 19: 69-75. PMID 1849260 DOI: 10.1093/nar/19.1.69  1
1991 Hoffman DW, Query CC, Golden BL, White SW, Keene JD. RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins. Proceedings of the National Academy of Sciences of the United States of America. 88: 2495-9. PMID 1826055  1
1991 Bentley RC, Keene JD. Recognition of U1 and U2 small nuclear RNAs can be altered by a 5-amino-acid segment in the U2 small nuclear ribonucleoprotein particle (snRNP) B" protein and through interactions with U2 snRNP-A' protein. Molecular and Cellular Biology. 11: 1829-39. PMID 1826042  1
1991 Fresco LD, Harper DS, Keene JD. Leucine periodicity of U2 small nuclear ribonucleoprotein particle (snRNP) A' protein is implicated in snRNP assembly via protein-protein interactions. Molecular and Cellular Biology. 11: 1578-89. PMID 1825347  1
1991 Tsai DE, Harper DS, Keene JD. U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts. Nucleic Acids Research. 19: 4931-6. PMID 1717938 DOI: 10.1093/nar/19.18.4931  1
1991 Kenan DJ, Query CC, Keene JD. RNA recognition: towards identifying determinants of specificity. Trends in Biochemical Sciences. 16: 214-20. PMID 1716386 DOI: 10.1016/0968-0004(91)90088-D  1
1991 Keene JD, Query CC. Nuclear RNA-binding proteins. Progress in Nucleic Acid Research and Molecular Biology. 41: 179-202. PMID 1715588  1
1990 Kelekar A, Keene JD. Downregulation of RNA polymerase III transcription of the hY3 gene in vitro. Molecular Biology Reports. 14: 173-4. PMID 2362573 DOI: 10.1007/BF00360463  1
1990 Harper DS, Fresco LD, Keene JD. Characterization of a Drosophila U snRNP RNA-binding protein. Molecular Biology Reports. 14: 163. PMID 2141901 DOI: 10.1007/BF00360458  1
1990 St Clair EW, Query CC, Bentley R, Keene JD, Polisson RP, Allen NB, Caldwell DS, Rice JR, Cox C, Pisetsky DS. Expression of autoantibodies to recombinant (U1) RNP-associated 70K antigen in systemic lupus erythematosus. Clinical Immunology and Immunopathology. 54: 266-80. PMID 2104788 DOI: 10.1016/0090-1229(90)90088-8  1
1990 Sunde L, Kjeldsen E, Andoh T, Keene JD, Bolund L. A three allele TaqI polymorphism at TOP1 gene. Nucleic Acids Research. 18: 5919. PMID 1977141 DOI: 10.1093/nar/18.19.5919-a  1
1990 Lutz-Freyermuth C, Query CC, Keene JD. Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA. Proceedings of the National Academy of Sciences of the United States of America. 87: 6393-7. PMID 1696729  1
1990 St Clair EW, Kenan D, Burch JA, Keene JD, Pisetsky DS. The fine specificity of anti-La antibodies induced in mice by immunization with recombinant human La autoantigen. Journal of Immunology (Baltimore, Md. : 1950). 144: 3868-76. PMID 1692063  1
1990 James JA, Dickey WD, Fujisaku A, O'Brien CA, Deutscher SL, Keene JD, Harley JB. Antigenicity of a recombinant Ro (SS-A) fusion protein. Arthritis and Rheumatism. 33: 102-6. PMID 1689160  1
1990 St Clair EW, Burch JA, Ward MM, Keene JD, Pisetsky DS. Temporal correlation of antibody responses to different epitopes of the human La autoantigen. The Journal of Clinical Investigation. 85: 515-21. PMID 1688887 DOI: 10.1172/JCI114467  1
1989 Crone DE, Keene JD. Viral transcription is necessary and sufficient for vesicular stomatitis virus to inhibit maturation of small nuclear ribonucleoproteins. Journal of Virology. 63: 4172-80. PMID 2550663  1
1989 Frielle DW, Kim PB, Keene JD. Inhibitory effects of vesicular stomatitis virus on cellular and influenza viral RNA metabolism and protein synthesis. Virology. 172: 274-84. PMID 2549715 DOI: 10.1016/0042-6822(89)90129-3  1
1989 Query CC, Bentley RC, Keene JD. A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component. Molecular and Cellular Biology. 9: 4872-81. PMID 2532301  1
1989 Lutz-Freyermuth C, Keene JD, Lutz-Reyermuth C. The U1 RNA-binding site of the U1 small nuclear ribonucleoprotein (snRNP)-associated A protein suggests a similarity with U2 snRNPs. Molecular and Cellular Biology. 9: 2975-82. PMID 2528681  1
1989 St Clair EW, Talal N, Moutsopoulos HM, Ballester A, Zerva L, Keene JD, Pisetsky DS. Epitope specificity of anti-La antibodies from patients with Sjögren's syndrome. Journal of Autoimmunity. 2: 335-44. PMID 2477000 DOI: 10.1016/0896-8411(89)90161-3  1
1989 Keene JD. Molecular structure of the La and Ro autoantigens and their use in autoimmune diagnostics. Journal of Autoimmunity. 2: 329-34. PMID 2476999 DOI: 10.1016/0896-8411(89)90160-1  1
1989 Query CC, Bentley RC, Keene JD. A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein. Cell. 57: 89-101. PMID 2467746 DOI: 10.1016/0092-8674(89)90175-X  1
1988 Deutscher SL, Harley JB, Keene JD. Molecular analysis of the 60-kDa human Ro ribonucleoprotein. Proceedings of the National Academy of Sciences of the United States of America. 85: 9479-83. PMID 3200833  1
1988 Chambers JC, Kenan D, Martin BJ, Keene JD. Genomic structure and amino acid sequence domains of the human La autoantigen. The Journal of Biological Chemistry. 263: 18043-51. PMID 3192525  1
1988 St Clair EW, Pisetsky DS, Reich CF, Chambers JC, Keene JD. Quantitative immunoassay of anti-La antibodies using purified recombinant La antigen. Arthritis and Rheumatism. 31: 506-14. PMID 3128988  1
1988 St Clair EW, Pisetsky DS, Reich CF, Keene JD. Analysis of autoantibody binding to different regions of the human La antigen expressed in recombinant fusion proteins. Journal of Immunology (Baltimore, Md. : 1950). 141: 4173-80. PMID 2461985  1
1988 Deutscher SL, Keene JD. A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody. Proceedings of the National Academy of Sciences of the United States of America. 85: 3299-303. PMID 2453054  1
1987 Fresco LD, Kurilla MG, Keene JD. Rapid inhibition of processing and assembly of small nuclear ribonucleoproteins after infection with vesicular stomatitis virus Molecular and Cellular Biology. 7: 1148-1155. PMID 3031484  1
1987 Query CC, Keene JD. A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. Cell. 51: 211-20. PMID 2959371 DOI: 10.1016/0092-8674(87)90148-6  1
1987 Deutscher SL, Harley JB, Keene JD. Molecular characterization of the Ro small cytoplasmic RNPS Molecular Biology Reports. 12: 242. DOI: 10.1007/BF00356920  1
1987 Chambers JC, Keene JD. Association between autoimmune epitopes and RNA binding domains of the human Lupus La protein Molecular Biology Reports. 12: 241. DOI: 10.1007/BF00356919  1
1987 Keene JD, Deutscher SL, Kenan D, Kelekar A. Nature of the la and ro RNPs Molecular Biology Reports. 12: 235-238. DOI: 10.1007/BF00356917  1
1987 Query CC, Keene JD. The U1 RNA-specific 70K protein: RNA-binding studies and autoimmune cross-reactivity with type-C retroviruses Molecular Biology Reports. 12: 158. DOI: 10.1007/BF00356875  1
1987 Fresco LD, Keene JD. Molecular analysis of the U2 snRNP unique protein A′ Molecular Biology Reports. 12: 155. DOI: 10.1007/BF00356873  1
1986 Kiley MP, Wilusz J, Mc Cormick JB, Keene JD. Conservation of the 3′ terminal nucleotide sequences of Ebola and Marburg virus Virology. 149: 251-254. PMID 3946083 DOI: 10.1016/0042-6822(86)90127-3  1
1986 Wilusz J, Keene JD. Autoantibodies specific for U1 RNA and initiator methionine tRNA Journal of Biological Chemistry. 261: 5467-5472. PMID 2420801  1
1985 Kole R, Fresco LD, Keene JD, Cohen PL, Eisenberg RA, Andrews PG. Alu RNA-protein complexes formed in vitro react with a novel lupus autoantibody Journal of Biological Chemistry. 260: 11781-11786. PMID 4044579  1
1985 Kurilla MG, Stone HO, Keene JD. RNA sequence and transcriptional properties of the 3′ end of the Newcastle disease virus genome Virology. 145: 203-212. PMID 4024452 DOI: 10.1016/0042-6822(85)90154-0  1
1985 Pisetsky DS, Hoch SO, Klatt CL, O'Donnell MA, Keene JD. Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity Journal of Immunology. 135: 4080-4085. PMID 3877763  1
1985 Chambers JC, Keene JD. Isolation and analysis of cDNA clones expressing human lupus La antigen Proceedings of the National Academy of Sciences of the United States of America. 82: 2115-2119. PMID 3856888  1
1985 Piwnica-Worms H, Keene JD. Replication of the vesicular stomatitis virus genome in permissive and nonpermissive host cells Journal of Biological Chemistry. 260: 10503-10511. PMID 2993276  1
1985 Wilusz J, Youngner JS, Keene JD. Base mutations in the terminal noncoding regions of the genome of vesicular stomatitis virus isolated from persistent infections of L cells Virology. 140: 249-256. PMID 2982234 DOI: 10.1016/0042-6822(85)90363-0  1
1985 Keene JD. Interactions between small viral RNAs of vesicular stomatitis virus and components of cellular gene expression Microbiological Sciences. 2: 152-156. PMID 2856377  1
1984 Kurilla MG, Cabradilla CD, Holloway BP, Keene JD. Nucleotide sequence and host La protein interactions of rabies virus leader RNA Journal of Virology. 50: 773-778. PMID 6328006  1
1984 Wilusz J, Keene JD. Interactions of plus and minus strand leader RNAs of the New Jersey serotype of vesicular stomatitis virus with the cellular La protein Virology. 135: 65-73. PMID 6203219 DOI: 10.1016/0042-6822(84)90117-X  1
1984 Meier E, Harmison GG, Keene JD, Schubert M. Sites of copy choice replication involved in generation of vesicular stomatitis virus defective-interfering particle RNAs Journal of Virology. 51: 515-521. PMID 6086960  1
1983 Kurilla MG, Keene JD. The leader RNA of vesicular stomatitis virus is bound by a cellular protein reactive with anti-La lupus antibodies Cell. 34: 837-845. PMID 6313210 DOI: 10.1016/0092-8674(83)90541-X  1
1983 Wilusz J, Kurilla MG, Keene JD. A host protein (La) binds to a unique species of minus-sense leader RNA during replication of vesicular stomatitis virus Proceedings of the National Academy of Sciences of the United States of America. 80: 5827-5831. PMID 6310594  1
1983 Piwnica-Worms H, Keene JD. Sequential synthesis of small capped RNA transcripts in Vitro by vesicular stomatitis virus Virology. 125: 206-218. PMID 6299007 DOI: 10.1016/0042-6822(83)90074-0  1
1983 Chambers JC, Kurilla MG, Keene JD. Association between the 7 S RNA and the lupus La protein varies among cell types Journal of Biological Chemistry. 258: 11438-11441. PMID 6194154  1
1982 Gaillard RK, Li JKK, Keene JD, Joklik WK. The sequences at the termini of four genes of the three reovirus serotypes Virology. 121: 320-326. PMID 7123853 DOI: 10.1016/0042-6822(82)90171-4  1
1982 Kurilla MG, Piwnica-Worms H, Keene JD. Rapid and transient localization of the leader RNA of vesicular stomatitis virus in the nuclei of infected cells Proceedings of the National Academy of Sciences of the United States of America. 79: 5240-5244. PMID 6291035  1
1982 Isaac CL, Keene JD. RNA polymerase-associated interactions near template promoter sequences of defective interfering particles of vesicular stomatitis virus Journal of Virology. 43: 241-249. PMID 6286999  1
1982 Schmidt EV, Keene JD, Linial M, Smith RE. Association of 3′ terminal RNA sequences with avian leukosis viruses causing a high incidence of osteopetrosis Virology. 116: 163-180. PMID 6278705 DOI: 10.1016/0042-6822(82)90411-1  1
1982 Lazzarini RA, Chien I, Yang F, Keene JD. The metabolic fate of independently initiated VSV mRNA transcripts. The Journal of General Virology. 58: 429-41. PMID 6278064  1
1981 Lazzarini RA, Keene JD, Schubert M. The origins of defective interfering particles of the negative-strand RNA viruses. Cell. 26: 145-54. PMID 7037195 DOI: 10.1016/0092-8674(81)90298-1  1
1981 Keene JD, Thornton BJ, Emerson SU. Sequence-specific contacts between the RNA polymerase of vesicular stomatitis virus and the leader RNA gene Proceedings of the National Academy of Sciences of the United States of America. 78: 6191-6195. PMID 6273858  1
1981 Isaac CL, Keene JD. Transfer RNAs associated with vesicular stomatitis virus Journal of General Virology. 56: 141-151. PMID 6271911  1
1981 Keene JD, Chien IM, Lazzarini RA. Vesicular stomatitis virus defective interfering particle containing a muted internal leader RNA gene. Proceedings of the National Academy of Sciences of the United States of America. 78: 2090-4. PMID 6264463  1
1980 Li JKK, Scheible PP, Keene JD, Joklik WK. The plus strand of reovirus gene S2 is identical with its in vitro transcript Virology. 105: 282-286. PMID 7414954  1
1980 Herman RC, Schubert M, Keene JD, Lazzarini RA. Polycistronic vesicular stomatitis virus RNA transcripts. Proceedings of the National Academy of Sciences of the United States of America. 77: 4662-5. PMID 6254036  1
1980 Keene JD, Schubert M, Lazzarini RA. Intervening sequence between the leader region and the nucleopcapsid gene of vesicular stomatitis virus RNA. Journal of Virology. 33: 789-94. PMID 6251249  1
1980 Schubert M, Keene JD, Herman RC, Lazzarini RA. Site on the vesicular stomatitis virus genome specifying polyadenylation and the end of the L gene mRNA. Journal of Virology. 34: 550-9. PMID 6246280  1
1980 Li JKK, Keene JD, Scheible PP, Joklik WK. Nature of the 3'-terminal sequences of the plus and minus strands of the S1 gene of reovirus serotypes 1, 2 and 3 Virology. 105: 41-51. PMID 6158163  1
1979 Keene JD, Schubert M, Lazzarini RA. Terminal sequences of vesicular stomatitis virus RNA are both complementary and conserved. Journal of Virology. 32: 167-74. PMID 232169  1
1979 Schubert M, Keene JD, Lazzarini RA. A specific internal RNA polymerase recognition site of VSV RNA is involved in the generation of DI particles. Cell. 18: 749-57. PMID 229963 DOI: 10.1016/0092-8674(79)90128-4  1
1978 Schubert M, Keene JD, Lazzarini RA, Emerson SU. The complete sequence of a unique RNA species synthesized by a DI particle of VSV. Cell. 15: 103-12. PMID 212197 DOI: 10.1016/0092-8674(78)90086-7  1
1978 Keene JD, Schubert M, Lazzarini RA, Rosenberg M. Nucleotide sequence homology at the 3' termini of RNA from vesicular stomatitis virus and its defective interfering particles. Proceedings of the National Academy of Sciences of the United States of America. 75: 3225-9. PMID 210454  1
1977 Colonno RJ, Lazzarini RA, Keene JD, Banerjee AK. In vitro synthesis of messenger RNA by a defective interfering particle of vesicular stomatitis virus. Proceedings of the National Academy of Sciences of the United States of America. 74: 1884-8. PMID 194241  1
1977 Keene JD, Rosenberg M, Lazzarini RA. Characterization of the 3' terminus of RNA isolated from vesicular stomatitis virus and from its defective interfering particles. Proceedings of the National Academy of Sciences of the United States of America. 74: 1353-7. PMID 193096  1
1976 Keene JD, Lazzarini RA. A comparison of the extents of methylation of vesicular stomatitis virus messenger RNA. Virology. 69: 364-7. PMID 174297 DOI: 10.1016/0042-6822(76)90229-4  1
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