| Year |
Citation |
Score |
| 2024 |
Peng K, Anmangandla A, Jana S, Jin Y, Lin H. Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. Acs Chemical Biology. PMID 38237916 DOI: 10.1021/acschembio.3c00512 |
0.53 |
|
| 2023 |
Smith MR, Zhang L, Jin Y, Yang M, Bade A, Gillis KD, Jana S, Bypaneni RN, Glass TE, Lin H. A Turn-On Fluorescent Amino Acid Sensor Reveals Chloroquine's Effect on Cellular Amino Acids via Inhibiting Cathepsin L. Acs Central Science. 9: 980-991. PMID 37252359 DOI: 10.1021/acscentsci.2c01325 |
0.494 |
|
| 2023 |
Anmangandla A, Jana S, Peng K, Wallace SD, Bagde SR, Drown BS, Xu J, Hergenrother PJ, Fromme JC, Lin H. A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. Acs Chemical Biology. PMID 37126856 DOI: 10.1021/acschembio.3c00092 |
0.507 |
|
| 2023 |
O'Brien C, Ling T, Berman JM, Culp-Hill R, Reisz JA, Rondeau V, Jahangiri S, St-Germain J, Macwan V, Astori A, Zeng A, Hong JY, Li M, Yang M, Jana S, ... ... Lin H, et al. Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity. Haematologica. PMID 37021547 DOI: 10.3324/haematol.2022.281894 |
0.523 |
|
| 2023 |
Wang ZA, Markert JW, Whedon SD, Yapa Abeywardana M, Lee K, Jiang H, Suarez C, Lin H, Farnung L, Cole PA. Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. Journal of the American Chemical Society. PMID 36930461 DOI: 10.1021/jacs.2c13512 |
0.414 |
|
| 2022 |
Latifkar A, Wang F, Mullmann JJ, Panizza E, Fernandez IR, Ling L, Miller AD, Fischbach C, Weiss RS, Lin H, Cerione RA, Antonyak MA. IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200477119. PMID 36322753 DOI: 10.1073/pnas.2200477119 |
0.777 |
|
| 2022 |
Miller SP, Maio G, Zhang X, Badillo Soto FS, Zhu J, Ramirez SZ, Lin H. A proteomic approach identifies isoform-specific and nucleotide-dependent RAS interactions. Molecular & Cellular Proteomics : McP. 100268. PMID 35839996 DOI: 10.1016/j.mcpro.2022.100268 |
0.324 |
|
| 2022 |
Wang F, Latifkar A, Mullmann J, Panizza E, Fernandez I, Ling L, Miller A, Fischbach C, Weiss R, Lin H, Cerione R, Antonyak M. IGF2BP2 Promotes Cancer Progression by Degrading the RNA Transcript Encoding a v-ATPase Subunit. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35552659 DOI: 10.1096/fasebj.2022.36.S1.L7433 |
0.51 |
|
| 2022 |
Wang ZA, Whedon SD, Wu M, Wang S, Brown EA, Anmangandla A, Regan L, Lee K, Du J, Hong JY, Fairall L, Kay T, Lin H, Zhao Y, Schwabe JWR, et al. Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase. Journal of the American Chemical Society. PMID 35175758 DOI: 10.1021/jacs.1c13555 |
0.409 |
|
| 2021 |
Hong JY, Malgapo MIP, Liu Y, Yang M, Zhu C, Zhang X, Tolbert P, Linder ME, Lin H. Correction to "High-Throughput Enzyme Assay for Screening Inhibitors of the ZDHHC3/7/20 Acyltransferases". Acs Chemical Biology. PMID 34514789 DOI: 10.1021/acschembio.1c00674 |
0.336 |
|
| 2021 |
Hong JY, Malgapo MIP, Liu Y, Yang M, Zhu C, Zhang X, Tolbert P, Linder ME, Lin H. High-Throughput Enzyme Assay for Screening Inhibitors of the ZDHHC3/7/20 Acyltransferases. Acs Chemical Biology. PMID 34374518 DOI: 10.1021/acschembio.1c00258 |
0.382 |
|
| 2021 |
Abril YLN, Fernandez IR, Hong JY, Chiang YL, Kutateladze DA, Zhao Q, Yang M, Hu J, Sadhukhan S, Li B, He B, Remick B, Bai JJ, Mullmann J, Wang F, ... ... Lin H, et al. Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer. Oncogene. PMID 33479498 DOI: 10.1038/s41388-020-01637-w |
0.666 |
|
| 2020 |
Zhang L, Cao J, Dong L, Lin H. TiPARP forms nuclear condensates to degrade HIF-1α and suppress tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32482854 DOI: 10.1073/Pnas.1921815117 |
0.307 |
|
| 2020 |
Kosciuk T, Lin H. NMT as a glycine and lysine myristoyltransferase in cancer, immunity, and infections. Acs Chemical Biology. PMID 32453941 DOI: 10.1021/Acschembio.0C00314 |
0.378 |
|
| 2020 |
Kosciuk T, Price IR, Zhang X, Zhu C, Johnson KN, Zhang S, Halaby SL, Komaniecki GP, Yang M, DeHart CJ, Thomas PM, Kelleher NL, Christopher Fromme J, Lin H. NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nature Communications. 11: 1067. PMID 32103017 DOI: 10.1038/S41467-020-14893-X |
0.695 |
|
| 2020 |
Fenwick MK, Su D, Dong M, Lin H, Ealick SE. Structural basis of substrate selectivity of viperin. Biochemistry. PMID 31917549 DOI: 10.1021/Acs.Biochem.9B00741 |
0.331 |
|
| 2019 |
Greene KS, Lukey MJ, Wang X, Blank B, Druso JE, Lin MJ, Stalnecker CA, Zhang C, Negrón Abril Y, Erickson JW, Wilson KF, Lin H, Weiss RS, Cerione RA. SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31843902 DOI: 10.1073/Pnas.1911954116 |
0.537 |
|
| 2019 |
Fenwick MK, Dong M, Lin H, Ealick SE. Crystal structure of Dph2 in complex with elongation factor 2 reveals structural basis for first step of diphthamide biosynthesis. Biochemistry. PMID 31566354 DOI: 10.1021/Acs.Biochem.9B00718 |
0.328 |
|
| 2019 |
Dong M, Dando EE, Kotliar I, Su X, Dzikovski B, Freed JH, Lin H. The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 31463593 DOI: 10.1007/S00775-019-01702-0 |
0.509 |
|
| 2019 |
Spiegelman NA, Zhang X, Jing H, Cao J, Kotliar IB, Aramsangtienchai P, Wang M, Tong Z, Rosch KM, Lin H. SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration. Acs Chemical Biology. PMID 31433161 DOI: 10.1021/Acschembio.9B00492 |
0.455 |
|
| 2019 |
Hong JY, Price IR, Bai JJ, Lin H. A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors. Acs Chemical Biology. PMID 31373792 DOI: 10.1021/Acschembio.9B00384 |
0.327 |
|
| 2019 |
Son SI, Cao J, Zhu CL, Miller SP, Lin H. Activity-Guided Design of HDAC11-Specific Inhibitors. Acs Chemical Biology. PMID 31264832 DOI: 10.1021/Acschembio.9B00292 |
0.585 |
|
| 2019 |
Li M, Chiang YL, Lyssiotis CA, Teater MR, Hong JY, Shen H, Wang L, Hu J, Jing H, Chen Z, Jain N, Duy C, Mistry SJ, Cerchietti L, Cross JR, ... ... Lin H, et al. Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis. Cancer Cell. 35: 916-931.e9. PMID 31185214 DOI: 10.1016/J.Ccell.2019.05.002 |
0.541 |
|
| 2019 |
Zhang S, Spiegelman NA, Lin H. Global Profiling of Sirtuin Deacylase Substrates Using a Chemical Proteomic Strategy and Validation by Fluorescent Labeling. Methods in Molecular Biology (Clifton, N.J.). 2009: 137-147. PMID 31152401 DOI: 10.1007/978-1-4939-9532-5_11 |
0.374 |
|
| 2019 |
Young Hong J, Cao J, Lin H. Fluorogenic Assays for the Defatty-Acylase Activity of Sirtuins. Methods in Molecular Biology (Clifton, N.J.). 2009: 129-136. PMID 31152400 DOI: 10.1007/978-1-4939-9532-5_10 |
0.359 |
|
| 2019 |
Farooqi AS, Hong JY, Cao J, Lu X, Price IR, Zhao Q, Kosciuk T, Yang M, Bai JJ, Lin H. Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model. Journal of Medicinal Chemistry. PMID 30986062 DOI: 10.1021/Acs.Jmedchem.9B00191 |
0.313 |
|
| 2019 |
Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, Hartman J, Fischbach C, Lin H, Cerione RA, Antonyak MA. Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Developmental Cell. PMID 30982660 DOI: 10.1016/J.Devcel.2019.03.011 |
0.763 |
|
| 2019 |
Kosciuk T, Wang M, Hong JY, Lin H. Updates on the epigenetic roles of sirtuins. Current Opinion in Chemical Biology. 51: 18-29. PMID 30875552 DOI: 10.1016/J.Cbpa.2019.01.023 |
0.372 |
|
| 2019 |
Cao J, Sun L, Aramsangtienchai P, Spiegelman NA, Zhang X, Huang W, Seto E, Lin H. HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2. Proceedings of the National Academy of Sciences of the United States of America. PMID 30819897 DOI: 10.1073/Pnas.1815365116 |
0.462 |
|
| 2019 |
Spiegelman NA, Hong JY, Hu J, Jing H, Wang M, Price IR, Cao J, Yang M, Zhang X, Lin H. A Small Molecule SIRT2 Inhibitor that Promotes K-Ras4a Lysine Fatty-acylation. Chemmedchem. PMID 30734528 DOI: 10.1002/Cmdc.201800715 |
0.446 |
|
| 2019 |
Wang WW, Angulo-Ibanez M, Lyu J, Kurra Y, Tong Z, Wu B, Zhang L, Sharma V, Zhou J, Lin H, Gao YQ, Li W, Chua KF, Liu WR. A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7. Journal of the American Chemical Society. PMID 30653310 DOI: 10.1021/Jacs.8B12083 |
0.372 |
|
| 2018 |
Zhang Y, Lin Z, Wang M, Lin H. Selective usage of isozymes for stress response. Acs Chemical Biology. PMID 30346689 DOI: 10.1021/Acschembio.8B00767 |
0.357 |
|
| 2018 |
Hong JY, Zhang X, Lin H. HPLC-Based Enzyme Assays for Sirtuins. Methods in Molecular Biology (Clifton, N.J.). 1813: 225-234. PMID 30097871 DOI: 10.1007/978-1-4939-8588-3_15 |
0.499 |
|
| 2018 |
Dong M, Zhang Y, Lin H. Methods for Studying the Radical SAM Enzymes in Diphthamide Biosynthesis. Methods in Enzymology. 606: 421-438. PMID 30097101 DOI: 10.1016/Bs.Mie.2018.04.001 |
0.371 |
|
| 2018 |
Spiegelman NA, Price IR, Jing H, Wang M, Yang M, Cao J, Hong JY, Zhang X, Aramsangtienchai P, Sadhukhan S, Lin H. Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-Dependent Inhibition, and On-target Anticancer Activities. Chemmedchem. PMID 30058233 DOI: 10.1002/Cmdc.201800391 |
0.432 |
|
| 2018 |
Dong M, Zhang Y, Lin H. Non-canonical radical SAM enzyme chemistry learned from diphthamide biosynthesis. Biochemistry. PMID 29708734 DOI: 10.1021/Acs.Biochem.8B00287 |
0.373 |
|
| 2018 |
Dong M, Kathiresan V, Fenwick MK, Torelli AT, Zhang Y, Caranto JD, Dzikovski B, Sharma A, Lancaster KM, Freed JH, Ealick SE, Hoffman BM, Lin H. Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis. Science (New York, N.Y.). 359: 1247-1250. PMID 29590073 DOI: 10.1126/Science.Aao6595 |
0.331 |
|
| 2018 |
Lin H, Caroll KS. Introduction: Posttranslational Protein Modification. Chemical Reviews. 118: 887-888. PMID 29439579 DOI: 10.1021/Acs.Chemrev.7B00756 |
0.317 |
|
| 2018 |
Zhang X, Cao J, Miller SP, Jing H, Lin H. Comparative Nucleotide-Dependent Interactome Analysis Reveals Shared and Differential Properties of KRas4a and KRas4b. Acs Central Science. 4: 71-80. PMID 29392178 DOI: 10.1021/Acscentsci.7B00440 |
0.442 |
|
| 2018 |
Jiang H, Zhang X, Chen X, Aramsangtienchai P, Tong Z, Lin H. Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies. Chemical Reviews. PMID 29292991 DOI: 10.1021/Acs.Chemrev.6B00750 |
0.444 |
|
| 2018 |
Latifkar A, Ling L, Zhang X, Fischbach C, Lin H, Cerione R, Antonyak M. Abstract 4506: Loss of SIRT1 alters the secretome of breast cancer cells by impairing lysosomal integrity Cancer Research. 78: 4506-4506. DOI: 10.1158/1538-7445.Am2018-4506 |
0.763 |
|
| 2017 |
Jing H, Zhang X, Wisner SA, Chen X, Spiegelman NA, Linder ME, Lin H. SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a. Elife. 6. PMID 29239724 DOI: 10.7554/Elife.32436 |
0.432 |
|
| 2017 |
Zhang L, Lin H. Using Clickable NAD(+) Analogs to Label Substrate Proteins of PARPs. Methods in Molecular Biology (Clifton, N.J.). 1608: 95-109. PMID 28695506 DOI: 10.1007/978-1-4939-6993-7_8 |
0.421 |
|
| 2017 |
Zhang X, Spiegelman NA, Nelson OD, Jing H, Lin H. SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. Elife. 6. PMID 28406396 DOI: 10.7554/Elife.25158 |
0.397 |
|
| 2017 |
Dong M, Horitani M, Dzikovski B, Freed JH, Ealick S, Hoffman BM, Lin H. Substrate-Dependent Cleavage Site Selection by Unconventional Radical SAM Enzymes in Diphthamide Biosynthesis. Journal of the American Chemical Society. PMID 28383907 DOI: 10.1021/Jacs.7B01712 |
0.333 |
|
| 2017 |
Aramsangtienchai P, Spiegelman NA, Cao J, Lin H. S-Palmitoylation of Junctional Adhesion Molecule C Regulates Its Tight Junction Localization and Cell Migration. The Journal of Biological Chemistry. PMID 28196865 DOI: 10.1074/Jbc.M116.730523 |
0.306 |
|
| 2017 |
Wang ZA, Kurra Y, Wang X, Zeng Y, Lee YJ, Sharma V, Lin H, Dai SY, Liu WR. A Versatile Approach for Site-Specific Lysine Acylation in Proteins. Angewandte Chemie (International Ed. in English). PMID 28042700 DOI: 10.1002/Anie.201611415 |
0.38 |
|
| 2017 |
Jing H, Zhang X, Wisner SA, Chen X, Spiegelman NA, Linder ME, Lin H. Author response: SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a Elife. DOI: 10.7554/Elife.32436.026 |
0.381 |
|
| 2017 |
Zhang X, Spiegelman NA, Nelson OD, Jing H, Lin H. Author response: SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation Elife. DOI: 10.7554/Elife.25158.019 |
0.373 |
|
| 2017 |
Li M, Chiang Y, Lyssiotis C, Teater M, Shen H, Wang L, Hong JY, Jin H, Duy C, Mistry S, Cerchietti L, Cross J, Cantley L, Lin H, Melnick A. SIRT3 Is a Novel Metabolic Driver of and Therapeutic Target for Chemotherapy Resistant Dlbcls Blood. 130: 643-643. DOI: 10.1182/Blood.V130.Suppl_1.643.643 |
0.32 |
|
| 2016 |
Tong Z, Wang M, Wang Y, Kim DD, Grenier JK, Cao J, Sadhukhan S, Hao Q, Lin H. SIRT7 Is an RNA-Activated Protein Lysine Deacylase. Acs Chemical Biology. PMID 27997115 DOI: 10.1021/Acschembio.6B00954 |
0.348 |
|
| 2016 |
Lin Z, Dong M, Zhang Y, Lee EA, Lin H. Cbr1 is a Dph3 reductase required for the tRNA wobble uridine modification. Nature Chemical Biology. PMID 27694803 DOI: 10.1038/Nchembio.2190 |
0.391 |
|
| 2016 |
Jin J, He B, Lin H, Wang Y. SIRT2 reverses 4-oxononanoyl lysine modification on histones. Journal of the American Chemical Society. PMID 27610633 DOI: 10.1021/Jacs.6B04977 |
0.339 |
|
| 2016 |
Dong M, Horitani M, Dzikovski B, Pandelia ME, Krebs C, Freed JH, Hoffman BM, Lin H. An organometallic complex formed by an unconventional radical SAM enzyme. Journal of the American Chemical Society. PMID 27465315 DOI: 10.1021/Jacs.6B04155 |
0.329 |
|
| 2016 |
Aramsangtienchai P, Spiegelman NA, He B, Miller SP, Dai L, Zhao Y, Lin H. HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine. Acs Chemical Biology. PMID 27459069 DOI: 10.1021/Acschembio.6B00396 |
0.358 |
|
| 2016 |
Zhang X, Khan S, Jiang H, Antonyak MA, Chen X, Spiegelman NA, Shrimp JH, Cerione RA, Lin H. Identifying the functional contribution of the defatty-acylase activity of SIRT6. Nature Chemical Biology. PMID 27322069 DOI: 10.1038/Nchembio.2106 |
0.606 |
|
| 2016 |
Gibson BA, Zhang Y, Jiang H, Hussey KM, Shrimp JH, Lin H, Schwede F, Yu Y, Kraus WL. Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation. Science (New York, N.Y.). PMID 27256882 DOI: 10.1126/Science.Aaf7865 |
0.382 |
|
| 2016 |
Jing H, Hu J, He B, Negrón Abril YL, Stupinski J, Weiser K, Carbonaro M, Chiang YL, Southard T, Giannakakou P, Weiss RS, Lin H. A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. Cancer Cell. 29: 767-768. PMID 27165747 DOI: 10.1016/J.Ccell.2016.04.005 |
0.579 |
|
| 2016 |
Bheda P, Jing H, Wolberger C, Lin H. The Substrate Specificity of Sirtuins. Annual Review of Biochemistry. PMID 27088879 DOI: 10.1146/Annurev-Biochem-060815-014537 |
0.362 |
|
| 2016 |
Jiang H, Zhang X, Lin H. Lysine fatty acylation promotes lysosomal targeting of TNF-α. Scientific Reports. 6: 24371. PMID 27079798 DOI: 10.1038/Srep24371 |
0.366 |
|
| 2016 |
Jing H, Hu J, He B, Negrón Abril YL, Stupinski J, Weiser K, Carbonaro M, Chiang YL, Southard T, Giannakakou P, Weiss RS, Lin H. A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. Cancer Cell. 29: 607. PMID 27070708 DOI: 10.1016/j.ccell.2016.03.011 |
0.52 |
|
| 2016 |
Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H. Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function. Proceedings of the National Academy of Sciences of the United States of America. PMID 27051063 DOI: 10.1073/Pnas.1519858113 |
0.342 |
|
| 2016 |
Jing H, Hu J, He B, Negrón Abril YL, Stupinski J, Weiser K, Carbonaro M, Chiang YL, Southard T, Giannakakou P, Weiss RS, Lin H. A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. Cancer Cell. 29: 297-310. PMID 26977881 DOI: 10.1016/j.ccell.2016.02.007 |
0.533 |
|
| 2016 |
Tong Z, Wang Y, Zhang X, Kim DD, Sadhukhan S, Hao Q, Lin H. SIRT7 is activated by DNA and deacetylates histone H3 in the chromatin context. Acs Chemical Biology. PMID 26907567 DOI: 10.1021/Acschembio.5B01084 |
0.448 |
|
| 2016 |
Chiang YL, Lin H. An improved fluorogenic assay for SIRT1, SIRT2, and SIRT3. Organic & Biomolecular Chemistry. PMID 26796034 DOI: 10.1039/C5Ob02609A |
0.583 |
|
| 2015 |
Li Z, Kim DD, Nelson OD, Otwell AE, Richardson RE, Callister SJ, Lin H. Molecular dissection of a putative iron reductase from Desulfotomaculum reducens MI-1. Biochemical and Biophysical Research Communications. PMID 26454174 DOI: 10.1016/J.Bbrc.2015.10.016 |
0.314 |
|
| 2015 |
Jing H, Lin H. Sirtuins in epigenetic regulation. Chemical Reviews. 115: 2350-75. PMID 25804908 DOI: 10.1021/Cr500457H |
0.376 |
|
| 2015 |
Teng YB, Jing H, Aramsangtienchai P, He B, Khan S, Hu J, Lin H, Hao Q. Efficient demyristoylase activity of SIRT2 revealed by kinetic and structural studies. Scientific Reports. 5: 8529. PMID 25704306 DOI: 10.1038/Srep08529 |
0.378 |
|
| 2015 |
Otwell AE, Sherwood RW, Zhang S, Nelson OD, Li Z, Lin H, Callister SJ, Richardson RE. Identification of proteins capable of metal reduction from the proteome of the Gram-positive bacterium Desulfotomaculum reducens MI-1 using an NADH-based activity assay. Environmental Microbiology. 17: 1977-90. PMID 25389064 DOI: 10.1111/1462-2920.12673 |
0.346 |
|
| 2014 |
He B, Hu J, Zhang X, Lin H. Thiomyristoyl peptides as cell-permeable Sirt6 inhibitors. Organic & Biomolecular Chemistry. 12: 7498-502. PMID 25163004 DOI: 10.1039/C4Ob00860J |
0.412 |
|
| 2014 |
Hu J, Jing H, Lin H. Sirtuin inhibitors as anticancer agents. Future Medicinal Chemistry. 6: 945-66. PMID 24962284 DOI: 10.4155/Fmc.14.44 |
0.397 |
|
| 2014 |
Lin Z, Su X, Chen W, Ci B, Zhang S, Lin H. Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis. Journal of the American Chemical Society. 136: 6179-82. PMID 24739148 DOI: 10.1021/Ja5009272 |
0.544 |
|
| 2014 |
Shrimp JH, Hu J, Dong M, Wang BS, MacDonald R, Jiang H, Hao Q, Yen A, Lin H. Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe. Journal of the American Chemical Society. 136: 5656-63. PMID 24660829 DOI: 10.1021/Ja411046J |
0.538 |
|
| 2014 |
Luo Q, Tang L, Lin H, Huang J, Zhang T, Liu Y, Wang J, Zhan P, Yin X, Su X, Ji Q, Yu D, Xu L. The oncogenic role of PKCiota gene amplification and overexpression in Chinese non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 84: 190-5. PMID 24636699 DOI: 10.1016/j.lungcan.2013.08.029 |
0.382 |
|
| 2014 |
Feng GD, Shi M, Ma L, Chen P, Wang BJ, Zhang M, Chang XL, Su XC, Yang YN, Fan XH, Dai W, Liu TT, He Y, Bian T, Duan LX, ... ... Lin H, et al. Diagnostic accuracy of intracellular mycobacterium tuberculosis detection for tuberculous meningitis. American Journal of Respiratory and Critical Care Medicine. 189: 475-81. PMID 24450377 DOI: 10.1164/rccm.201309-1686OC |
0.361 |
|
| 2014 |
Dong M, Su X, Dzikovski B, Dando EE, Zhu X, Du J, Freed JH, Lin H. Dph3 is an electron donor for Dph1-Dph2 in the first step of eukaryotic diphthamide biosynthesis. Journal of the American Chemical Society. 136: 1754-7. PMID 24422557 DOI: 10.1021/Ja4118957 |
0.776 |
|
| 2013 |
Colak G, Xie Z, Zhu AY, Dai L, Lu Z, Zhang Y, Wan X, Chen Y, Cha YH, Lin H, Zhao Y, Tan M. Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. Molecular & Cellular Proteomics : McP. 12: 3509-20. PMID 24176774 DOI: 10.1074/Mcp.M113.031567 |
0.418 |
|
| 2013 |
Yu J, Sadhukhan S, Noriega LG, Moullan N, He B, Weiss RS, Lin H, Schoonjans K, Auwerx J. Metabolic characterization of a Sirt5 deficient mouse model. Scientific Reports. 3: 2806. PMID 24076663 DOI: 10.1038/Srep02806 |
0.312 |
|
| 2013 |
Zhu A, Su X, Lin H. Detecting sirtuin-catalyzed deacylation reactions using ³²P-labeled NAD and thin-layer chromatography. Methods in Molecular Biology (Clifton, N.J.). 1077: 179-89. PMID 24014407 DOI: 10.1007/978-1-62703-637-5_12 |
0.555 |
|
| 2013 |
Su X, Lin Z, Lin H. The biosynthesis and biological function of diphthamide. Critical Reviews in Biochemistry and Molecular Biology. 48: 515-21. PMID 23971743 DOI: 10.3109/10409238.2013.831023 |
0.512 |
|
| 2013 |
Hu J, He B, Bhargava S, Lin H. A fluorogenic assay for screening Sirt6 modulators. Organic & Biomolecular Chemistry. 11: 5213-6. PMID 23839075 DOI: 10.1039/C3Ob41138A |
0.323 |
|
| 2013 |
Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 496: 110-3. PMID 23552949 DOI: 10.1038/Nature12038 |
0.386 |
|
| 2013 |
Jiang H, Sherwood R, Zhang S, Zhu X, Liu Q, Graeff R, Kriksunov IA, Lee HC, Hao Q, Lin H. Identification of ADP-ribosylation sites of CD38 mutants by precursor ion scanning mass spectrometry. Analytical Biochemistry. 433: 218-26. PMID 23123429 DOI: 10.1016/J.Ab.2012.10.029 |
0.719 |
|
| 2012 |
Jiang H, Lin H. Labeling Substrate Proteins of Poly(ADP-ribose) Polymerases with Clickable NAD Analog. Current Protocols in Chemical Biology. 4: 19-34. PMID 23187903 DOI: 10.1002/9780470559277.Ch110196 |
0.383 |
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| 2012 |
Su X, Lin Z, Chen W, Jiang H, Zhang S, Lin H. Chemogenomic approach identified yeast YLR143W as diphthamide synthetase. Proceedings of the National Academy of Sciences of the United States of America. 109: 19983-7. PMID 23169644 DOI: 10.1073/Pnas.1214346109 |
0.52 |
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| 2012 |
Zhou Y, Zhang H, He B, Du J, Lin H, Cerione RA, Hao Q. The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5). The Journal of Biological Chemistry. 287: 28307-14. PMID 22767592 DOI: 10.1074/Jbc.M112.384511 |
0.534 |
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| 2012 |
Lin H, Su X, He B. Protein lysine acylation and cysteine succination by intermediates of energy metabolism. Acs Chemical Biology. 7: 947-60. PMID 22571489 DOI: 10.1021/Cb3001793 |
0.527 |
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| 2012 |
He B, Du J, Lin H. Thiosuccinyl peptides as Sirt5-specific inhibitors. Journal of the American Chemical Society. 134: 1922-5. PMID 22263694 DOI: 10.1021/Ja2090417 |
0.343 |
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| 2012 |
Su X, Chen W, Lee W, Jiang H, Zhang S, Lin H. YBR246W is required for the third step of diphthamide biosynthesis. Journal of the American Chemical Society. 134: 773-6. PMID 22188241 DOI: 10.1021/Ja208870A |
0.547 |
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| 2012 |
Zhu AY, Zhou Y, Khan S, Deitsch KW, Hao Q, Lin H. Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine. Acs Chemical Biology. 7: 155-9. PMID 21992006 DOI: 10.1021/Cb200230X |
0.345 |
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| 2011 |
Du J, Zhou Y, Su X, Yu JJ, Khan S, Jiang H, Kim J, Woo J, Kim JH, Choi BH, He B, Chen W, Zhang S, Cerione RA, Auwerx J, ... ... Lin H, et al. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science (New York, N.Y.). 334: 806-9. PMID 22076378 DOI: 10.1126/Science.1207861 |
0.664 |
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| 2011 |
Lin H, Begley T. Protein posttranslational modifications: chemistry, biology, and applications. Molecular Biosystems. 7: 14-5. PMID 21107473 DOI: 10.1039/C0Mb90037K |
0.474 |
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| 2011 |
Zhu X, Dzikovski B, Su X, Torelli AT, Zhang Y, Ealick SE, Freed JH, Lin H. Mechanistic understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] enzyme required for diphthamide biosynthesis. Molecular Biosystems. 7: 74-81. PMID 20931132 DOI: 10.1039/C0Mb00076K |
0.772 |
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| 2011 |
Zhang Y, Zhu X, Torelli AT, Lee M, Dzikovski B, Koralewski RM, Wang E, Freed J, Krebs C, Ealick SE, Lin H. Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme (Nature (2010) 465 (891-896)) Nature. 473: 544. DOI: 10.1038/Nature10087 |
0.728 |
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| 2010 |
Zhu X, Kim J, Su X, Lin H. Reconstitution of diphthine synthase activity in vitro. Biochemistry. 49: 9649-57. PMID 20873788 DOI: 10.1021/Bi100812H |
0.785 |
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| 2010 |
Jiang H, Kim JH, Frizzell KM, Kraus WL, Lin H. Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases. Journal of the American Chemical Society. 132: 9363-72. PMID 20560583 DOI: 10.1021/Ja101588R |
0.389 |
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| 2010 |
Zhang Y, Zhu X, Torelli AT, Lee M, Dzikovski B, Koralewski RM, Wang E, Freed J, Krebs C, Ealick SE, Lin H. Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme. Nature. 465: 891-6. PMID 20559380 DOI: 10.1038/Nature09138 |
0.755 |
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| 2009 |
Du J, Jiang H, Lin H. Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD. Biochemistry. 48: 2878-90. PMID 19220062 DOI: 10.1021/Bi802093G |
0.392 |
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| 2008 |
Peralta-Yahya P, Carter BT, Lin H, Tao H, Cornish VW. High-throughput selection for cellulase catalysts using chemical complementation. Journal of the American Chemical Society. 130: 17446-52. PMID 19053460 DOI: 10.1021/Ja8055744 |
0.771 |
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| 2008 |
Liu Q, Kriksunov IA, Jiang H, Graeff R, Lin H, Lee HC, Hao Q. Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38. Chemistry & Biology. 15: 1068-78. PMID 18940667 DOI: 10.1016/J.Chembiol.2008.08.007 |
0.376 |
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| 2008 |
Shi J, Wei PK, Zhang S, Qin ZF, Li J, Sun DZ, Xiao Y, Yu ZH, Lin HM, Zheng GJ, Su XM, Chen YL, Liu YF, Xu L. OB glue paste technique for establishing nude mouse human gastric cancer orthotopic transplantation models. World Journal of Gastroenterology. 14: 4800-4. PMID 18720543 DOI: 10.3748/wjg.14.4800 |
0.356 |
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| 2007 |
Lin H. Nicotinamide adenine dinucleotide: beyond a redox coenzyme. Organic & Biomolecular Chemistry. 5: 2541-54. PMID 18019526 DOI: 10.1039/B706887E |
0.301 |
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| 2006 |
Luo M, Lin H, Fischbach MA, Liu DR, Walsh CT, Groves JT. Enzymatic tailoring of enterobactin alters membrane partitioning and iron acquisition. Acs Chemical Biology. 1: 29-32. PMID 17163637 DOI: 10.1021/Cb0500034 |
0.612 |
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| 2006 |
Fischbach MA, Lin H, Zhou L, Yu Y, Abergel RJ, Liu DR, Raymond KN, Wanner BL, Strong RK, Walsh CT, Aderem A, Smith KD. The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proceedings of the National Academy of Sciences of the United States of America. 103: 16502-7. PMID 17060628 DOI: 10.1073/Pnas.0604636103 |
0.621 |
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| 2006 |
Larsen NA, Lin H, Wei R, Fischbach MA, Walsh CT. Structural characterization of enterobactin hydrolase IroE. Biochemistry. 45: 10184-90. PMID 16922493 DOI: 10.1021/bi060950i |
0.613 |
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| 2006 |
Tao H, Peralta-Yahya P, Lin H, Cornish VW. Optimized design and synthesis of chemical dimerizer substrates for detection of glycosynthase activity via chemical complementation. Bioorganic & Medicinal Chemistry. 14: 6940-53. PMID 16870451 DOI: 10.1016/J.Bmc.2006.06.034 |
0.788 |
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| 2006 |
Lin H, Fischbach MA, Gatto GJ, Liu DR, Walsh CT. Bromoenterobactins as potent inhibitors of a pathogen-associated, siderophore-modifying C-glycosyltransferase. Journal of the American Chemical Society. 128: 9324-5. PMID 16848455 DOI: 10.1021/Ja063236X |
0.629 |
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| 2006 |
Fischbach MA, Lin H, Liu DR, Walsh CT. How pathogenic bacteria evade mammalian sabotage in the battle for iron. Nature Chemical Biology. 2: 132-8. PMID 16485005 DOI: 10.1038/Nchembio771 |
0.633 |
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| 2005 |
Carter BT, Lin H, Goldberg SD, Althoff EA, Raushel J, Cornish VW. Investigation of the mechanism of resistance to third-generation cephalosporins by class C beta-lactamases by using chemical complementation. Chembiochem : a European Journal of Chemical Biology. 6: 2055-67. PMID 16250067 DOI: 10.1002/Cbic.200500058 |
0.749 |
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| 2005 |
Lin H, Fischbach MA, Liu DR, Walsh CT. In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes. Journal of the American Chemical Society. 127: 11075-84. PMID 16076215 DOI: 10.1021/Ja0522027 |
0.627 |
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| 2005 |
Fischbach MA, Lin H, Liu DR, Walsh CT. In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 102: 571-6. PMID 15598734 DOI: 10.1073/Pnas.0408463102 |
0.607 |
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| 2004 |
Lin H, Thayer DA, Wong CH, Walsh CT. Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase. Chemistry & Biology. 11: 1635-42. PMID 15610847 DOI: 10.1016/J.Chembiol.2004.09.015 |
0.436 |
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| 2004 |
Yeh E, Lin H, Clugston SL, Kohli RM, Walsh CT. Enhanced macrocyclizing activity of the thioesterase from tyrocidine synthetase in presence of nonionic detergent. Chemistry & Biology. 11: 1573-82. PMID 15556008 DOI: 10.1016/J.Chembiol.2004.09.003 |
0.735 |
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| 2004 |
Lin H, Tao H, Cornish VW. Directed evolution of a glycosynthase via chemical complementation. Journal of the American Chemical Society. 126: 15051-9. PMID 15548001 DOI: 10.1021/Ja046238V |
0.725 |
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| 2004 |
Lin H, Walsh CT. A chemoenzymatic approach to glycopeptide antibiotics. Journal of the American Chemical Society. 126: 13998-4003. PMID 15506762 DOI: 10.1021/Ja045147V |
0.465 |
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| 2004 |
Sengupta D, Lin H, Goldberg SD, Mahal JJ, Cornish VW. Correlation between catalytic efficiency and the transcription read-out in chemical complementation: a general assay for enzyme catalysis. Biochemistry. 43: 3570-81. PMID 15035627 DOI: 10.1021/Bi035810C |
0.799 |
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| 2003 |
Forster AC, Tan Z, Nalam MN, Lin H, Qu H, Cornish VW, Blacklow SC. Programming peptidomimetic syntheses by translating genetic codes designed de novo. Proceedings of the National Academy of Sciences of the United States of America. 100: 6353-7. PMID 12754376 DOI: 10.1073/Pnas.1132122100 |
0.679 |
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| 2002 |
Baker K, Bleczinski C, Lin H, Salazar-Jimenez G, Sengupta D, Krane S, Cornish VW. Chemical complementation: a reaction-independent genetic assay for enzyme catalysis. Proceedings of the National Academy of Sciences of the United States of America. 99: 16537-42. PMID 12482929 DOI: 10.1073/Pnas.262420099 |
0.733 |
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| 2002 |
Lin H, Cornish VW. Screening and selection methods for large-scale analysis of protein function. Angewandte Chemie (International Ed. in English). 41: 4402-25. PMID 12458502 DOI: 10.1002/1521-3773(20021202)41:23<4402::Aid-Anie4402>3.0.Co;2-H |
0.634 |
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| 2002 |
Abida WM, Carter BT, Althoff EA, Lin H, Cornish VW. Receptor-dependence of the transcription read-out in a small-molecule three-hybrid system. Chembiochem : a European Journal of Chemical Biology. 3: 887-95. PMID 12210990 DOI: 10.1002/1439-7633(20020902)3:9<887::Aid-Cbic887>3.0.Co;2-F |
0.765 |
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| 2002 |
Lin H, Cornish VW. Screening- und Selektionsmethoden für die Analyse von Proteinfunktionen in großem Maßstab Angewandte Chemie. 114: 4580-4606. DOI: 10.1002/1521-3757(20021202)114:23<4580::Aid-Ange4580>3.0.Co;2-P |
0.599 |
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| 2001 |
Lin H, Cornish VW. In Vivo Protein-Protein Interaction Assays: Beyond Proteins. Angewandte Chemie (International Ed. in English). 40: 871-875. PMID 29712174 DOI: 10.1002/1521-3773(20010302)40:5<871::Aid-Anie871>3.0.Co;2-S |
0.62 |
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| 2001 |
Lin H, Cornish VW. In Vivo Protein-Protein Interaction Assays: Beyond Proteins We would like to thank Tony Siu, Dr. Charles Cho, and the members of our lab for their helpful comments as we were preparing this manuscript. Angewandte Chemie (International Ed. in English). 40: 871-875. PMID 11241632 DOI: 10.1002/1521-3773(20010302)40:5<871::AID-ANIE871>3.0.CO;2-S |
0.577 |
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| 2001 |
Lin H, Cornish VW. In-vivo-Testsysteme für Protein-Protein-Wechselwirkungen: eine Methode nicht nur für Proteine Angewandte Chemie. 113: 895-899. DOI: 10.1002/1521-3757(20010302)113:5<895::Aid-Ange895>3.0.Co;2-L |
0.601 |
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| 2000 |
Lin H, Abida WM, Sauer RT, Cornish VW. Dexamethasone-methotrexate: An efficient chemical inducer of protein dimerization in vivo [18] Journal of the American Chemical Society. 122: 4247-4248. DOI: 10.1021/Ja9941532 |
0.683 |
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| 1999 |
Zhao G, Lin H, Yu P, Sun H, Zhu S, Su X, Chen Y. Ethylenediamine-palladium(II) complexes with pyridine and its derivatives: synthesis, molecular structure and initial antitumor studies. Journal of Inorganic Biochemistry. 73: 145-9. PMID 10331244 |
0.362 |
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| 1998 |
Zhao G, Sun H, Lin H, Zhu S, Su X, Chen Y. Palladium(II) complexes with N,N'-dialkyl-1,10-phenanthroline-2,9-dimathanamine: synthesis, characterization and cytotoxic activity. Journal of Inorganic Biochemistry. 72: 173-7. PMID 10065535 |
0.355 |
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