Year |
Citation |
Score |
2022 |
Soave C, Ducker C, Kim S, Strahl T, Rosati R, Huang Y, Shaw P, Ratnam M. Identification of ELK1 interacting peptide segments in the androgen receptor. The Biochemical Journal. PMID 35781489 DOI: 10.1042/BCJ20220297 |
0.379 |
|
2020 |
Rosati R, Oppat K, Huang Y, Kim S, Ratnam M. Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models. Bmc Cancer. 20: 512. PMID 32493230 DOI: 10.1186/s12885-020-07002-0 |
0.308 |
|
2019 |
Pardy L, Rosati R, Soave C, Huang Y, Kim S, Ratnam M. The ternary complex factor protein ELK1 is an independent prognosticator of disease recurrence in prostate cancer. The Prostate. PMID 31794091 DOI: 10.1002/pros.23932 |
0.385 |
|
2018 |
Patki M, McFall T, Rosati R, Huang Y, Malysa A, Polin L, Fielder A, Wilson MR, Lonardo F, Back J, Li J, Matherly LH, Bepler G, Ratnam M. Chronic p27 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor. Scientific Reports. 8: 16006. PMID 30375484 DOI: 10.1038/S41598-018-34475-8 |
0.735 |
|
2018 |
Rosati R, Polin LA, Ducker C, Li J, Bao X, Selvakumar D, Kim S, Xhabija B, Larsen M, McFall T, Huang Y, Kidder BL, Fribley A, Saxton J, Kakuta H, ... ... Ratnam M, et al. Strategy for Tumor Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30185422 DOI: 10.1158/1078-0432.Ccr-18-0982 |
0.464 |
|
2018 |
Frontera ED, Khansa RM, Schalk DL, Leakan LE, Guerin-Edbauer TJ, Ratnam M, Gorski DH, Speyer CL. IgA Fc-folate conjugate activates and recruits neutrophils to directly target triple-negative breast cancer cells. Breast Cancer Research and Treatment. PMID 30155754 DOI: 10.1007/s10549-018-4941-5 |
0.314 |
|
2016 |
Rosati R, Patki M, Chari V, Dakshnamurthy S, McFall T, Saxton J, Kidder BL, Shaw PE, Ratnam M. The Amino-terminal Domain of the Androgen Receptor Co-opts ERK Docking Sites in ELK1 to Induce Sustained Gene Activation that Supports Prostate Cancer Cell Growth. The Journal of Biological Chemistry. PMID 27793987 DOI: 10.1074/Jbc.M116.745596 |
0.793 |
|
2016 |
Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M, Qin Z. Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease HSP90 and the Androgen Receptor Levels and Inhibit Viability in Enzalutamide Resistant C4-2 Prostate Cancer Cells. Molecular Pharmacology. PMID 27382012 DOI: 10.1124/Mol.116.103416 |
0.77 |
|
2016 |
Patki M, Huang Y, Ratnam M. Restoration of the cellular secretory milieu overrides androgen dependence of in vivo generated castration resistant prostate cancer cells overexpressing the androgen receptor. Biochemical and Biophysical Research Communications. PMID 27179779 DOI: 10.1016/J.Bbrc.2016.05.058 |
0.807 |
|
2015 |
McFall T, Patki M, Rosati R, Ratnam M. Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges. Oncotarget. 6: 33146-64. PMID 26356672 DOI: 10.18632/Oncotarget.5082 |
0.752 |
|
2015 |
Patki M, Salazar Md, Trumbly R, Ratnam M. Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells. Biochemical and Biophysical Research Communications. 457: 404-11. PMID 25582774 DOI: 10.1016/J.Bbrc.2015.01.004 |
0.746 |
|
2015 |
McFall T, Patki M, Rosati R, Ratnam M. Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges Oncotarget. 6: 33146-33164. DOI: 10.18632/oncotarget.5082 |
0.756 |
|
2015 |
Patki M, D'Alincourt Salazar M, Trumbly R, Ratnam M. Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells Biochemical and Biophysical Research Communications. 457: 404-411. DOI: 10.1016/j.bbrc.2015.01.004 |
0.761 |
|
2014 |
Patki M, Gadgeel S, Huang Y, McFall T, Shields AF, Matherly LH, Bepler G, Ratnam M. Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 519-526. PMID 24736075 DOI: 10.1097/Jto.0000000000000111 |
0.743 |
|
2014 |
Shen M, Zhang Z, Ratnam M, Dou QP. The interplay of AMP-activated protein kinase and androgen receptor in prostate cancer cells. Journal of Cellular Physiology. 229: 688-95. PMID 24129850 DOI: 10.1002/jcp.24494 |
0.47 |
|
2013 |
Patki M, Chari V, Sivakumaran S, Gonit M, Trumbly R, Ratnam M. The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells Journal of Biological Chemistry. 288: 11047-11065. PMID 23426362 DOI: 10.1074/Jbc.M112.438473 |
0.719 |
|
2013 |
Ratnam M, Patki M, Gonit M, Trumbly R. Mechanisms of ARE-independent gene activation by the androgen receptor in prostate cancer cells: Potential targets for better intervention strategies Androgen-Responsive Genes in Prostate Cancer: Regulation, Function and Clinical Applications. 2147483647: 85-100. DOI: 10.1007/978-1-4614-6182-1_6 |
0.79 |
|
2011 |
Gonit M, Zhang J, d'Alincourt Salazar M, Cui H, Shatnawi A, Trumbly R, Ratnam M. Hormone depletion-insensitivity of prostate cancer cells is supported by the AR without binding to classical response elements Molecular Endocrinology. 25: 621-634. PMID 21330406 DOI: 10.1210/Me.2010-0409 |
0.836 |
|
2011 |
Salazar MD, Ratnam M, Patki M, Kisovic I, Trumbly R, Iman M. During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein Breast Cancer Research. 13. PMID 21299862 DOI: 10.1186/Bcr2827 |
0.76 |
|
2010 |
Sivakumaran S, Zhang J, Kelley KM, Gonit M, Hao H, Ratnam M. Androgen activation of the folate receptor α gene through partial tethering of the androgen receptor by C/EBPα. The Journal of Steroid Biochemistry and Molecular Biology. 122: 333-40. PMID 20817090 DOI: 10.1016/j.jsbmb.2010.08.008 |
0.741 |
|
2010 |
Zhang J, Gonit M, Salazar MD, Shatnawi A, Shemshedini L, Trumbly R, Ratnam M. C/EBPα redirects androgen receptor signaling through a unique bimodal interaction Oncogene. 29: 723-738. PMID 19901962 DOI: 10.1038/Onc.2009.373 |
0.826 |
|
2009 |
Elnakat H, Gonit M, Salazar MDA, Zhang J, Basrur V, Gunning W, Kamen B, Ratnam M. Regulation of folate receptor internalization by protein kinase C Biochemistry. 48: 8249-8260. PMID 19639961 DOI: 10.1021/Bi900565T |
0.792 |
|
2008 |
Zhang J, Wilkinson JE, Gonit M, Keck R, Selman S, Ratnam M. Expression and sub-cellular localization of the CCAAT/enhancer binding protein α in relation to postnatal development and malignancy of the prostate Prostate. 68: 1206-1214. PMID 18481268 DOI: 10.1002/Pros.20779 |
0.812 |
|
2007 |
Lu Y, Wu J, Wu J, Gonit M, Yang X, Lee A, Xiang G, Li H, Liu S, Marcucci G, Ratnam M, Lee RJ. Role of formulation composition in folate receptor-targeted liposomal doxorubicin delivery to acute myelogenous leukemia cells. Molecular Pharmaceutics. 4: 707-12. PMID 17708654 DOI: 10.1021/mp070058l |
0.765 |
|
2007 |
Blaser BW, Gonit M, Qi H, Shatnawi A, Guimond M, Lee RJ, Ratnam M. Induction of folate receptor type β in a bone marrow engraftment model of acute myelogenous leukemia [22] Leukemia. 21: 2233-2235. PMID 17554378 DOI: 10.1038/Sj.Leu.2404786 |
0.749 |
|
2006 |
Elnakat H, Ratnam M. Role of folate receptor genes in reproduction and related cancers Frontiers in Bioscience. 11: 506-519. PMID 16146749 DOI: 10.2741/1815 |
0.37 |
|
2005 |
Tran T, Shatnawi A, Zheng X, Kelley KM, Ratnam M. Enhancement of folate receptor alpha expression in tumor cells through the glucocorticoid receptor: a promising means to improved tumor detection and targeting. Cancer Research. 65: 4431-41. PMID 15899836 DOI: 10.1158/0008-5472.CAN-04-2890 |
0.315 |
|
2004 |
Elnakat H, Ratnam M. Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Advanced Drug Delivery Reviews. 56: 1067-84. PMID 15094207 DOI: 10.1016/j.addr.2004.01.001 |
0.305 |
|
1987 |
Lindstrom J, Criado M, Ratnam M, Whiting P, Ralston S, Rivier J, Sarin V, Sargent P. Using monoclonal antibodies to determine the structures of acetylcholine receptors from electric organs, muscles, and neurons Annals of the New York Academy of Sciences. 505: 208-225. PMID 2446548 DOI: 10.1111/J.1749-6632.1987.Tb51293.X |
0.407 |
|
1986 |
Ratnam M, Gullick W, Spiess J, Wan K, Criado M, Lindstrom J. Structural heterogeneity of the alpha subunits of the nicotinic acetylcholine receptor in relation to agonist affinity alkylation and antagonist binding. Biochemistry. 25: 4268-75. PMID 3756139 DOI: 10.1021/Bi00363A014 |
0.43 |
|
1986 |
Ratnam M, Sargent PB, Sarin V, Fox JL, Nguyen DL, Rivier J, Criado M, Lindstrom J. Location of antigenic determinants on primary sequences of subunits of nicotinic acetylcholine receptor by peptide mapping. Biochemistry. 25: 2621-32. PMID 2424498 DOI: 10.1021/Bi00357A051 |
0.438 |
|
1985 |
Lindstrom J, Hochschwender S, Wan K, Ratnam M, Criado M. Use of monoclonal antibodies in exploring the structure of the acetylcholine receptor Biochemical Society Transactions. 13: 14-16. PMID 3996735 DOI: 10.1042/Bst0130014 |
0.437 |
|
1984 |
Ratnam M, Lindstrom J. Structural features of the nicotinic acetylcholine receptor revealed by antibodies to synthetic peptides. Biochemical and Biophysical Research Communications. 122: 1225-1233. PMID 6206851 DOI: 10.1016/0006-291X(84)91223-3 |
0.481 |
|
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