| Year |
Citation |
Score |
| 2024 |
Gaikani HK, Stolar M, Kriti D, Nislow C, Giaever G. From beer to breadboards: yeast as a force for biological innovation. Genome Biology. 25: 10. PMID 38178179 DOI: 10.1186/s13059-023-03156-9 |
0.679 |
|
| 2023 |
Tremblay R, Mehrjoo Y, Ahmed O, Simoneau A, McQuaid ME, Affar EB, Nislow C, Giaever G, Wurtele H. Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication Origins. Molecular and Cellular Biology. 1-30. PMID 37811746 DOI: 10.1080/10985549.2023.2259739 |
0.635 |
|
| 2022 |
Barazandeh M, Kriti D, Nislow C, Giaever G. The cellular response to drug perturbation is limited: comparison of large-scale chemogenomic fitness signatures. Bmc Genomics. 23: 197. PMID 35277135 DOI: 10.1186/s12864-022-08395-x |
0.716 |
|
| 2021 |
Gaikani H, Smith AM, Lee AY, Giaever G, Nislow C. Systematic Prediction of Antifungal Drug Synergy by Chemogenomic Screening in . Frontiers in Fungal Biology. 2: 683414. PMID 37744101 DOI: 10.3389/ffunb.2021.683414 |
0.684 |
|
| 2021 |
Hammond TG, Nislow C, Christov IC, Batuman V, Nagrani PP, Barazandeh M, Upadhyay R, Giaever G, Allen PL, Armbruster M, Raymond A, Birdsall HH. Author Correction: Cell spinpods are a simple inexpensive suspension culture device to deliver fluid shear stress to renal proximal tubular cells. Scientific Reports. 11: 23166. PMID 34819606 DOI: 10.1038/s41598-021-02538-y |
0.597 |
|
| 2021 |
Hammond TG, Nislow C, Christov IC, Batuman V, Nagrani PP, Barazandeh M, Upadhyay R, Giaever G, Allen PL, Armbruster M, Raymond A, Birdsall HH. Cell spinpods are a simple inexpensive suspension culture device to deliver fluid shear stress to renal proximal tubular cells. Scientific Reports. 11: 21296. PMID 34716334 DOI: 10.1038/s41598-021-00304-8 |
0.631 |
|
| 2021 |
Gaikani H, Giaever G, Nislow C. Chemical-Genetic Interactions as a Means to Characterize Drug Synergy. Methods in Molecular Biology (Clifton, N.J.). 2381: 243-263. PMID 34590281 DOI: 10.1007/978-1-0716-1740-3_14 |
0.704 |
|
| 2021 |
Ogbede JU, Giaever G, Nislow C. A genome-wide portrait of pervasive drug contaminants. Scientific Reports. 11: 12487. PMID 34127714 DOI: 10.1038/s41598-021-91792-1 |
0.708 |
|
| 2020 |
Burns AR, Luciani GM, Musso G, Bagg R, Yeo M, Zhang Y, Rajendran L, Glavin J, Hunter R, Redman E, Stasiuk S, Schertzberg M, McQuibban GA, Caffrey CR, Cutler SR, ... ... Giaever G, et al. Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery. Nature Communications. 11: 3779. PMID 32709866 DOI: 10.1038/S41467-020-17617-3 |
0.635 |
|
| 2020 |
Edouarzin E, Horn C, Paudyal A, Zhang C, Lu J, Tong Z, Giaever G, Nislow C, Veerapandian R, Hua DH, Vediyappan G. Broad-spectrum antifungal activities and mechanism of drimane sesquiterpenoids. Microbial Cell (Graz, Austria). 7: 146-159. PMID 32548177 DOI: 10.15698/Mic2020.06.719 |
0.708 |
|
| 2020 |
Coutin NPJ, Giaever G, Nislow C. Interactively AUDIT Your Growth Curves with a Suite of R Packages. G3 (Bethesda, Md.). PMID 31974098 DOI: 10.1534/G3.119.400898 |
0.649 |
|
| 2019 |
Giaever G, Lissina E, Nislow C. Network dynamics of the yeast methyltransferome. Microbial Cell (Graz, Austria). 6: 356-369. PMID 31403050 DOI: 10.15698/Mic2019.08.687 |
0.679 |
|
| 2019 |
Nawrotek A, Benabdi S, Niyomchon S, Kryszke MH, Ginestier C, Cañeque T, Tepshi L, Mariani A, St Onge RP, Giaever G, Nislow C, Charafe-Jauffret E, Rodriguez R, Zeghouf M, Cherfils J. Publisher Correction: PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling. Nature Chemical Biology. PMID 30833779 DOI: 10.1038/S41589-019-0255-0 |
0.631 |
|
| 2019 |
Nawrotek A, Benabdi S, Niyomchon S, Kryszke MH, Ginestier C, Cañeque T, Tepshi L, Mariani A, St Onge RP, Giaever G, Nislow C, Charafe-Jauffret E, Rodriguez R, Zeghouf M, Cherfils J. PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling. Nature Chemical Biology. PMID 30742123 DOI: 10.1038/S41589-019-0228-3 |
0.67 |
|
| 2018 |
Hammond TG, Allen PL, Gunter MA, Chiang J, Giaever G, Nislow C, Birdsall HH. Physical Forces Modulate Oxidative Status and Stress Defense Meditated Metabolic Adaptation of Yeast Colonies: Spaceflight and Microgravity Simulations. Microgravity Science and Technology. 30: 195-208. PMID 31258252 DOI: 10.1007/S12217-017-9588-Z |
0.685 |
|
| 2018 |
Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, ... ... Giaever G, et al. Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids". Mbio. 9. PMID 29535196 DOI: 10.1128/Mbio.00188-18 |
0.638 |
|
| 2017 |
Acton E, Lee AH, Zhao PJ, Flibotte S, Neira M, Sinha S, Chiang J, Flaherty P, Nislow C, Giaever G. Comparative functional genomic screens of three yeast deletion collections reveal unexpected effects of genotype in response to diverse stress. Open Biology. 7. PMID 28592509 DOI: 10.1098/Rsob.160330 |
0.728 |
|
| 2017 |
Wong LH, Flibotte S, Sinha S, Chiang J, Giaever G, Nislow C. Genome-Wide Screen Reveals sec21 Mutants of Saccharomyces cerevisiae Are Methotrexate-Resistant. G3 (Bethesda, Md.). PMID 28235825 DOI: 10.1534/G3.116.038117 |
0.701 |
|
| 2016 |
Williamson AE, Ylioja PM, Robertson MN, Antonova-Koch Y, Avery V, Baell JB, Batchu H, Batra S, Burrows JN, Bhattacharyya S, Calderon F, Charman SA, Clark J, Crespo B, Dean M, ... ... Giaever G, et al. Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles. Acs Central Science. 2: 687-701. PMID 27800551 DOI: 10.1021/Acscentsci.6B00086 |
0.749 |
|
| 2016 |
Mathew MD, Mathew ND, Miller A, Simpson M, Au V, Garland S, Gestin M, Edgley ML, Flibotte S, Balgi A, Chiang J, Giaever G, Dean P, Tung A, Roberge M, et al. Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity. Plos Neglected Tropical Diseases. 10: e0005058. PMID 27755544 DOI: 10.1371/Journal.Pntd.0005058 |
0.696 |
|
| 2016 |
Kwon Y, Cha J, Chiang J, Tran G, Giaever G, Nislow C, Hur JS, Kwak YS. A chemogenomic approach to understand the anti-fungal action of Lichen-derived vulpinic acid. Journal of Applied Microbiology. PMID 27660105 DOI: 10.1111/Jam.13300 |
0.66 |
|
| 2016 |
Wong LH, Sinha S, Bergeron JR, Mellor JC, Giaever G, Flaherty P, Nislow C. Reverse Chemical Genetics: Comprehensive Fitness Profiling Reveals the Spectrum of Drug Target Interactions. Plos Genetics. 12: e1006275. PMID 27588687 DOI: 10.1371/Journal.Pgen.1006275 |
0.699 |
|
| 2016 |
Nislow C, Wong LH, Lee AH, Giaever G. Functional Genomics Using the Saccharomyces cerevisiae Yeast Deletion Collections. Cold Spring Harbor Protocols. 2016: pdb.top080945. PMID 27587784 DOI: 10.1101/Pdb.Top080945 |
0.74 |
|
| 2016 |
Suresh S, Schlecht U, Xu W, Bray W, Miranda M, Davis RW, Nislow C, Giaever G, Lokey RS, St Onge RP. Systematic Mapping of Chemical-Genetic Interactions in Saccharomyces cerevisiae. Cold Spring Harbor Protocols. 2016: pdb.top077701. PMID 27587783 DOI: 10.1101/Pdb.Top077701 |
0.778 |
|
| 2016 |
Suresh S, Schlecht U, Xu W, Miranda M, Davis RW, Nislow C, Giaever G, St Onge RP. Identification of Chemical-Genetic Interactions via Parallel Analysis of Barcoded Yeast Strains. Cold Spring Harbor Protocols. 2016: pdb.prot088054. PMID 27587778 DOI: 10.1101/Pdb.Prot088054 |
0.768 |
|
| 2016 |
Nislow C, Wong LH, Lee AH, Giaever G. Functional Profiling Using the Saccharomyces Genome Deletion Project Collections. Cold Spring Harbor Protocols. 2016: pdb.prot088039. PMID 27587776 DOI: 10.1101/Pdb.Prot088039 |
0.738 |
|
| 2016 |
Kwon Y, Chiang J, Tran G, Giaever G, Nislow C, Hahn BS, Kwak YS, Koo JC. Signaling pathways coordinating the alkaline pH response confer resistance to the hevein-type plant antimicrobial peptide Pn-AMP1 in Saccharomyces cerevisiae. Planta. PMID 27510723 DOI: 10.1007/S00425-016-2579-2 |
0.697 |
|
| 2016 |
Jeyaraju DV, Hurren R, Wang X, MacLean N, Gronda M, Shamas-Din A, Minden MD, Giaever G, Schimmer AD. A novel isoflavone, ME-344, targets the cytoskeleton in acute myeloid leukemia. Oncotarget. PMID 27391350 DOI: 10.18632/Oncotarget.10446 |
0.323 |
|
| 2016 |
Kennedy MA, Moffat TC, Gable K, Ganesan S, Niewola-Staszkowska K, Johnston A, Nislow C, Giaever G, Harris LJ, Loewith R, Zaremberg V, Harper ME, Dunn T, Bennett SA, Baetz K. A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction. Scientific Reports. 6: 19332. PMID 26757638 DOI: 10.1038/Srep19332 |
0.668 |
|
| 2016 |
Simoneau A, Ricard É, Weber S, Hammond-Martel I, Wong LH, Sellam A, Giaever G, Nislow C, Raymond M, Wurtele H. Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress. Nucleic Acids Research. PMID 26748095 DOI: 10.1093/Nar/Gkv1537 |
0.692 |
|
| 2015 |
Hamza A, Tammpere E, Kofoed M, Keong C, Chiang J, Giaever G, Nislow C, Hieter P. Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants. Genetics. 201: 1263-74. PMID 26354769 DOI: 10.1534/Genetics.115.181099 |
0.773 |
|
| 2015 |
Pandyra AA, Mullen PJ, Goard CA, Ericson E, Sharma P, Kalkat M, Yu R, Pong JT, Brown KR, Hart T, Gebbia M, Lang KS, Giaever G, Nislow C, Moffat J, et al. Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death. Oncotarget. PMID 26353928 DOI: 10.18632/Oncotarget.4817 |
0.705 |
|
| 2015 |
Kofoed M, Milbury KL, Chiang JH, Sinha S, Ben-Aroya S, Giaever G, Nislow C, Hieter P, Stirling PC. An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential Genes. G3 (Bethesda, Md.). PMID 26175450 DOI: 10.1534/G3.115.019174 |
0.776 |
|
| 2015 |
Burns AR, Luciani GM, Musso G, Bagg R, Yeo M, Zhang Y, Rajendran L, Glavin J, Hunter R, Redman E, Stasiuk S, Schertzberg M, Angus McQuibban G, Caffrey CR, Cutler SR, ... ... Giaever G, et al. Caenorhabditis elegans is a useful model for anthelmintic discovery. Nature Communications. 6: 7485. PMID 26108372 DOI: 10.1038/Ncomms8485 |
0.703 |
|
| 2015 |
Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, ... ... Giaever G, et al. Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids. Mbio. 6. PMID 26106079 DOI: 10.1128/Mbio.00647-15 |
0.72 |
|
| 2015 |
Cha JY, Han S, Hong HJ, Cho H, Kim D, Kwon Y, Kwon SK, Crüsemann M, Bok Lee Y, Kim JF, Giaever G, Nislow C, Moore BS, Thomashow LS, Weller DM, et al. Microbial and biochemical basis of a Fusarium wilt-suppressive soil. The Isme Journal. PMID 26057845 DOI: 10.1038/Ismej.2015.95 |
0.649 |
|
| 2015 |
Bernard D, Gebbia M, Prabha S, Gronda M, MacLean N, Wang X, Hurren R, Sukhai MA, Cho EE, Manolson MF, Datti A, Wrana J, Minden MD, Al-Awar R, Aman A, ... ... Giaever G, et al. Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Apoptosis : An International Journal On Programmed Cell Death. 20: 948-59. PMID 25832785 DOI: 10.1007/S10495-015-1123-3 |
0.711 |
|
| 2015 |
Nislow C, Lee AY, Allen PL, Giaever G, Smith A, Gebbia M, Stodieck LS, Hammond JS, Birdsall HH, Hammond TG. Genes required for survival in microgravity revealed by genome-wide yeast deletion collections cultured during spaceflight. Biomed Research International. 2015: 976458. PMID 25667933 DOI: 10.1155/2015/976458 |
0.744 |
|
| 2015 |
Jeyaraju DV, Hurren R, Wang X, MacLean N, Gronda M, Jordan CT, Minden MD, Giaever G, Schimmer AD. A Novel Isoflavone, ME-344, Targets the Cytoskeleton in Acute Myeloid Leukemia Blood. 126: 3682-3682. DOI: 10.1182/Blood.V126.23.3682.3682 |
0.361 |
|
| 2014 |
Arnoldo A, Kittanakom S, Heisler LE, Mak AB, Shukalyuk AI, Torti D, Moffat J, Giaever G, Nislow C. A genome scale overexpression screen to reveal drug activity in human cells. Genome Medicine. 6: 32. PMID 24944581 DOI: 10.1186/Gm549 |
0.736 |
|
| 2014 |
Giaever G, Nislow C. The yeast deletion collection: a decade of functional genomics. Genetics. 197: 451-65. PMID 24939991 DOI: 10.1534/Genetics.114.161620 |
0.707 |
|
| 2014 |
Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, ... ... Giaever G, et al. Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (New York, N.Y.). 344: 208-11. PMID 24723613 DOI: 10.1126/Science.1250217 |
0.823 |
|
| 2014 |
Cokol M, Weinstein ZB, Yilancioglu K, Tasan M, Doak A, Cansever D, Mutlu B, Li S, Rodriguez-Esteban R, Akhmedov M, Guvenek A, Cokol M, Cetiner S, Giaever G, Iossifov I, et al. Large-scale identification and analysis of suppressive drug interactions. Chemistry & Biology. 21: 541-51. PMID 24704506 DOI: 10.1016/J.Chembiol.2014.02.012 |
0.682 |
|
| 2014 |
Nile AH, Tripathi A, Yuan P, Mousley CJ, Suresh S, Wallace IM, Shah SD, Pohlhaus DT, Temple B, Nislow C, Giaever G, Tropsha A, Davis RW, St Onge RP, Bankaitis VA. PITPs as targets for selectively interfering with phosphoinositide signaling in cells. Nature Chemical Biology. 10: 76-84. PMID 24292071 DOI: 10.1038/Nchembio.1389 |
0.723 |
|
| 2014 |
Lee AY, Onge RPS, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear E, Han MKL, Schlecht U, ... ... Giaever G, et al. Erratum for the report: "Mapping the cellular response to small molecules using chemogenomic fitness signatures" (Science (2014) (208-211)) Science. 344: 1255771. DOI: 10.1126/Science.1255771 |
0.764 |
|
| 2013 |
Lissina E, Weiss D, Young B, Rella A, Cheung-Ong K, Del Poeta M, Clarke SG, Giaever G, Nislow C. A novel small molecule methyltransferase is important for virulence in Candida albicans. Acs Chemical Biology. 8: 2785-93. PMID 24083538 DOI: 10.1021/Cb400607H |
0.794 |
|
| 2013 |
Kittanakom S, Arnoldo A, Brown KR, Wallace I, Kunavisarut T, Torti D, Heisler LE, Surendra A, Moffat J, Giaever G, Nislow C. Miniature short hairpin rna screens to characterize antiproliferative drugs G3: Genes, Genomes, Genetics. 3: 1375-1387. PMID 23797109 DOI: 10.1534/G3.113.006437 |
0.73 |
|
| 2013 |
Torres NP, Lee AY, Giaever G, Nislow C, Brown GW. A high-throughput yeast assay identifies synergistic drug combinations. Assay and Drug Development Technologies. 11: 299-307. PMID 23772551 DOI: 10.1089/Adt.2012.503 |
0.705 |
|
| 2013 |
Cheung-Ong K, Giaever G, Nislow C. DNA-damaging agents in cancer chemotherapy: serendipity and chemical biology. Chemistry & Biology. 20: 648-59. PMID 23706631 DOI: 10.1016/J.Chembiol.2013.04.007 |
0.788 |
|
| 2013 |
Srikumar T, Lewicki MC, Costanzo M, Tkach JM, van Bakel H, Tsui K, Johnson ES, Brown GW, Andrews BJ, Boone C, Giaever G, Nislow C, Raught B. Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. The Journal of Cell Biology. 201: 145-63. PMID 23547032 DOI: 10.1083/Jcb.201210019 |
0.7 |
|
| 2013 |
Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, MacLean N, Cho EE, ... ... Giaever G, et al. Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors Journal of Clinical Investigation. 123: 315-328. PMID 23202731 DOI: 10.1172/Jci64180 |
0.704 |
|
| 2013 |
Bernard D, Gebbia M, Prabha S, Gronda M, MacLean N, Wang X, Hurren R, Sukhai MA, Cho EE, Manolson MF, Datti A, Wrana J, Al-Awar R, Aman A, Nislow C, ... Giaever G, et al. Abstract A299: Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A299 |
0.689 |
|
| 2012 |
Ammar R, Torti D, Tsui K, Gebbia M, Durbic T, Bader GD, Giaever G, Nislow C. Chromatin is an ancient innovation conserved between Archaea and Eukarya. Elife. 1: e00078. PMID 23240084 DOI: 10.7554/Elife.00078 |
0.674 |
|
| 2012 |
Alfred SE, Surendra A, Le C, Lin K, Mok A, Wallace IM, Proctor M, Urbanus ML, Giaever G, Nislow C. A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis. Genome Biology. 13: R105. PMID 23158586 DOI: 10.1186/Gb-2012-13-11-R105 |
0.716 |
|
| 2012 |
Douglas AC, Smith AM, Sharifpoor S, Yan Z, Durbic T, Heisler LE, Lee AY, Ryan O, Göttert H, Surendra A, van Dyk D, Giaever G, Boone C, Nislow C, Andrews BJ. Functional analysis with a barcoder yeast gene overexpression system. G3 (Bethesda, Md.). 2: 1279-89. PMID 23050238 DOI: 10.1534/G3.112.003400 |
0.739 |
|
| 2012 |
Orij R, Urbanus ML, Vizeacoumar FJ, Giaever G, Boone C, Nislow C, Brul S, Smits GJ. Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae. Genome Biology. 13: R80. PMID 23021432 DOI: 10.1186/Gb-2012-13-9-R80 |
0.65 |
|
| 2012 |
Shabtai D, Giaever G, Nislow C. An algorithm for chemical genomic profiling that minimizes batch effects: bucket evaluations. Bmc Bioinformatics. 13: 245. PMID 23009392 DOI: 10.1186/1471-2105-13-245 |
0.742 |
|
| 2012 |
Ryan O, Shapiro RS, Kurat CF, Mayhew D, Baryshnikova A, Chin B, Lin ZY, Cox MJ, Vizeacoumar F, Cheung D, Bahr S, Tsui K, Tebbji F, Sellam A, Istel F, ... ... Giaever G, et al. Global gene deletion analysis exploring yeast filamentous growth. Science (New York, N.Y.). 337: 1353-6. PMID 22984072 DOI: 10.1126/Science.1224339 |
0.708 |
|
| 2012 |
Cheung-Ong K, Song KT, Ma Z, Shabtai D, Lee AY, Gallo D, Heisler LE, Brown GW, Bierbach U, Giaever G, Nislow C. Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents. Acs Chemical Biology. 7: 1892-901. PMID 22928710 DOI: 10.1021/Cb300320D |
0.799 |
|
| 2012 |
Smith AM, Durbic T, Kittanakom S, Giaever G, Nislow C. Barcode sequencing for understanding drug-gene interactions. Methods in Molecular Biology (Clifton, N.J.). 910: 55-69. PMID 22821592 DOI: 10.1007/978-1-61779-965-5_4 |
0.687 |
|
| 2012 |
Singh-Babak SD, Shekhar T, Smith AM, Giaever G, Nislow C, Cowen LE. A novel calcineurin-independent activity of cyclosporin A in Saccharomyces cerevisiae. Molecular Biosystems. 8: 2575-84. PMID 22751784 DOI: 10.1039/C2Mb25107H |
0.728 |
|
| 2012 |
Jaime MD, Lopez-Llorca LV, Conesa A, Lee AY, Proctor M, Heisler LE, Gebbia M, Giaever G, Westwood JT, Nislow C. Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics. Bmc Genomics. 13: 267. PMID 22727066 DOI: 10.1186/1471-2164-13-267 |
0.654 |
|
| 2012 |
Blackman RK, Cheung-Ong K, Gebbia M, Proia DA, He S, Kepros J, Jonneaux A, Marchetti P, Kluza J, Rao PE, Wada Y, Giaever G, Nislow C. Mitochondrial electron transport is the cellular target of the oncology drug elesclomol. Plos One. 7: e29798. PMID 22253786 DOI: 10.1371/Journal.Pone.0029798 |
0.801 |
|
| 2012 |
Roemer T, Davies J, Giaever G, Nislow C. Bugs, drugs and chemical genomics. Nature Chemical Biology. 8: 46-56. PMID 22173359 DOI: 10.1038/Nchembio.744 |
0.73 |
|
| 2012 |
Ammar R, Torti D, Tsui K, Gebbia M, Durbic T, Bader GD, Giaever G, Nislow C. Author response: Chromatin is an ancient innovation conserved between Archaea and Eukarya Elife. DOI: 10.7554/Elife.00078.010 |
0.627 |
|
| 2012 |
Luciani GM, Magomedova L, Puckrin R, Urbanus ML, Wallace IM, Giaever G, Nislow C, Cummins CL, Roy PJ. Erratum: Corrigendum: Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans Nature Chemical Biology. 8: 318-318. DOI: 10.1038/Nchembio0312-318B |
0.641 |
|
| 2011 |
Hoon S, Gebbia M, Costanzo M, Davis RW, Giaever G, Nislow C. A global perspective of the genetic basis for carbonyl stress resistance. G3 (Bethesda, Md.). 1: 219-31. PMID 22384333 DOI: 10.1534/G3.111.000505 |
0.813 |
|
| 2011 |
Berry DB, Guan Q, Hose J, Haroon S, Gebbia M, Heisler LE, Nislow C, Giaever G, Gasch AP. Multiple means to the same end: the genetic basis of acquired stress resistance in yeast. Plos Genetics. 7: e1002353. PMID 22102822 DOI: 10.1371/Journal.Pgen.1002353 |
0.67 |
|
| 2011 |
Skrti? M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, ... ... Giaever G, et al. Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia. Cancer Cell. 20: 674-88. PMID 22094260 DOI: 10.1016/J.Ccr.2011.10.015 |
0.689 |
|
| 2011 |
Cokol M, Chua HN, Tasan M, Mutlu B, Weinstein ZB, Suzuki Y, Nergiz ME, Costanzo M, Baryshnikova A, Giaever G, Nislow C, Myers CL, Andrews BJ, Boone C, Roth FP. Systematic exploration of synergistic drug pairs. Molecular Systems Biology. 7: 544. PMID 22068327 DOI: 10.1038/Msb.2011.71 |
0.686 |
|
| 2011 |
Luciani GM, Magomedova L, Puckrin R, Urbanus ML, Wallace IM, Giaever G, Nislow C, Cummins CL, Roy PJ. Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans. Nature Chemical Biology. 7: 891-3. PMID 22057127 DOI: 10.1038/Nchembio.698 |
0.676 |
|
| 2011 |
Wallace IM, Urbanus ML, Luciani GM, Burns AR, Han MK, Wang H, Arora K, Heisler LE, Proctor M, St Onge RP, Roemer T, Roy PJ, Cummins CL, Bader GD, Nislow C, ... Giaever G, et al. Compound prioritization methods increase rates of chemical probe discovery in model organisms. Chemistry & Biology. 18: 1273-83. PMID 22035796 DOI: 10.1016/J.Chembiol.2011.07.018 |
0.7 |
|
| 2011 |
Lissina E, Young B, Urbanus ML, Guan XL, Lowenson J, Hoon S, Baryshnikova A, Riezman I, Michaut M, Riezman H, Cowen LE, Wenk MR, Clarke SG, Giaever G, Nislow C. A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. Plos Genetics. 7: e1002332. PMID 22028670 DOI: 10.1371/Journal.Pgen.1002332 |
0.812 |
|
| 2011 |
Minear S, O'Donnell AF, Ballew A, Giaever G, Nislow C, Stearns T, Cyert MS. Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryotic Cell. 10: 1574-81. PMID 21908599 DOI: 10.1128/Ec.05163-11 |
0.665 |
|
| 2011 |
Wallace IM, Bader GD, Giaever G, Nislow C. Displaying chemical information on a biological network using Cytoscape. Methods in Molecular Biology (Clifton, N.J.). 781: 363-76. PMID 21877291 DOI: 10.1007/978-1-61779-276-2_18 |
0.692 |
|
| 2011 |
Proctor M, Urbanus ML, Fung EL, Jaramillo DF, Davis RW, Nislow C, Giaever G. The automated cell: compound and environment screening system (ACCESS) for chemogenomic screening. Methods in Molecular Biology (Clifton, N.J.). 759: 239-69. PMID 21863492 DOI: 10.1007/978-1-61779-173-4_15 |
0.763 |
|
| 2011 |
Smith AM, Durbic T, Oh J, Urbanus M, Proctor M, Heisler LE, Giaever G, Nislow C. Competitive genomic screens of barcoded yeast libraries. Journal of Visualized Experiments : Jove. PMID 21860376 DOI: 10.3791/2864 |
0.738 |
|
| 2011 |
Bendaha H, Yu L, Touzani R, Souane R, Giaever G, Nislow C, Boone C, El Kadiri S, Brown GW, Bellaoui M. New azole antifungal agents with novel modes of action: synthesis and biological studies of new tridentate ligands based on pyrazole and triazole. European Journal of Medicinal Chemistry. 46: 4117-24. PMID 21723647 DOI: 10.1016/J.Ejmech.2011.06.012 |
0.704 |
|
| 2011 |
Klein M, Morillas M, Vendrell A, Brive L, Gebbia M, Wallace IM, Giaever G, Nislow C, Posas F, Grøtli M. Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases. Plos One. 6: e20789. PMID 21698101 DOI: 10.1371/Journal.Pone.0020789 |
0.676 |
|
| 2011 |
Dinér P, Veide Vilg J, Kjellén J, Migdal I, Andersson T, Gebbia M, Giaever G, Nislow C, Hohmann S, Wysocki R, Tamás MJ, Grøtli M. Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast. Plos One. 6: e20012. PMID 21655328 DOI: 10.1371/Journal.Pone.0020012 |
0.683 |
|
| 2011 |
Magtanong L, Ho CH, Barker SL, Jiao W, Baryshnikova A, Bahr S, Smith AM, Heisler LE, Choy JS, Kuzmin E, Andrusiak K, Kobylianski A, Li Z, Costanzo M, Basrai MA, ... Giaever G, et al. Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell. Nature Biotechnology. 29: 505-11. PMID 21572441 DOI: 10.1038/Nbt.1855 |
0.709 |
|
| 2011 |
Ketela T, Heisler LE, Brown KR, Ammar R, Kasimer D, Surendra A, Ericson E, Blakely K, Karamboulas D, Smith AM, Durbic T, Arnoldo A, Cheung-Ong K, Koh JL, Gopal S, ... ... Giaever G, et al. A comprehensive platform for highly multiplexed mammalian functional genetic screens. Bmc Genomics. 12: 213. PMID 21548937 DOI: 10.1186/1471-2164-12-213 |
0.812 |
|
| 2011 |
Tamble CM, St. Onge RP, Giaever G, Nislow C, Williams AG, Stuart JM, Lokey RS. The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiae Molecular Biosystems. 7: 2019-2030. PMID 21487606 DOI: 10.1039/C0Mb00298D |
0.742 |
|
| 2011 |
Li Z, Vizeacoumar FJ, Bahr S, Li J, Warringer J, Vizeacoumar FS, Min R, Vandersluis B, Bellay J, Devit M, Fleming JA, Stephens A, Haase J, Lin ZY, Baryshnikova A, ... ... Giaever G, et al. Systematic exploration of essential yeast gene function with temperature-sensitive mutants. Nature Biotechnology. 29: 361-7. PMID 21441928 DOI: 10.1038/Nbt.1832 |
0.734 |
|
| 2011 |
Suzuki Y, St Onge RP, Mani R, King OD, Heilbut A, Labunskyy VM, Chen W, Pham L, Zhang LV, Tong AH, Nislow C, Giaever G, Gladyshev VN, Vidal M, Schow P, et al. Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection. Nature Methods. 8: 159-64. PMID 21217751 DOI: 10.1038/Nmeth.1550 |
0.711 |
|
| 2011 |
Sukhai MA, Hurren R, Rutledge A, Livak B, Wang X, Seneviratne A, Cusimano MC, Gebbia M, Skrtic M, Sun H, Gronda M, Spagnuolo PA, Urbanus M, Eppert K, Dissanayake D, ... ... Giaever G, et al. Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production Blood. 118: 61-61. DOI: 10.1182/Blood.V118.21.61.61 |
0.708 |
|
| 2011 |
Skrtic M, Sriskanthadevan S, Livak B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai C, Eberhard Y, Bartoszko J, Spagnuolo PA, Rutledge A, ... ... Giaever G, et al. Inhibition of Mitochondrial Translation As a Therapeutic Strategy for Acute Myeloid Leukemia (AML) Blood. 118: 233-233. DOI: 10.1182/Blood.V118.21.233.233 |
0.671 |
|
| 2010 |
Oh J, Fung E, Schlecht U, Davis RW, Giaever G, St Onge RP, Deutschbauer A, Nislow C. Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection. Plos Pathogens. 6: e1001140. PMID 20949076 DOI: 10.1371/Journal.Ppat.1001140 |
0.821 |
|
| 2010 |
Ericson E, Hoon S, St Onge RP, Giaever G, Nislow C. Exploring gene function and drug action using chemogenomic dosage assays. Methods in Enzymology. 470: 233-55. PMID 20946813 DOI: 10.1016/S0076-6879(10)70010-0 |
0.819 |
|
| 2010 |
Fabrizio P, Hoon S, Shamalnasab M, Galbani A, Wei M, Giaever G, Nislow C, Longo VD. Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation. Plos Genetics. 6: e1001024. PMID 20657825 DOI: 10.1371/Journal.Pgen.1001024 |
0.796 |
|
| 2010 |
Smith AM, Ammar R, Nislow C, Giaever G. A survey of yeast genomic assays for drug and target discovery. Pharmacology & Therapeutics. 127: 156-64. PMID 20546776 DOI: 10.1016/J.Pharmthera.2010.04.012 |
0.742 |
|
| 2010 |
Burns AR, Wallace IM, Wildenhain J, Tyers M, Giaever G, Bader GD, Nislow C, Cutler SR, Roy PJ. A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans. Nature Chemical Biology. 6: 549-57. PMID 20512140 DOI: 10.1038/Nchembio.380 |
0.702 |
|
| 2010 |
Oh J, Fung E, Price MN, Dehal PS, Davis RW, Giaever G, Nislow C, Arkin AP, Deutschbauer A. A universal TagModule collection for parallel genetic analysis of microorganisms. Nucleic Acids Research. 38: e146. PMID 20494978 DOI: 10.1093/Nar/Gkq419 |
0.811 |
|
| 2010 |
Smith AM, Heisler LE, St.Onge RP, Farias-Hesson E, Wallace IM, Bodeau J, Harris AN, Perry KM, Giaever G, Pourmand N, Nislow C. Highly-multiplexed barcode sequencing: An efficient method for parallel analysis of pooled samples Nucleic Acids Research. 38: e142-e142. PMID 20460461 DOI: 10.1093/Nar/Gkq368 |
0.661 |
|
| 2010 |
Dowell RD, Ryan O, Jansen A, Cheung D, Agarwala S, Danford T, Bernstein DA, Rolfe PA, Heisler LE, Chin B, Nislow C, Giaever G, Phillips PC, Fink GR, Gifford DK, et al. Genotype to phenotype: a complex problem. Science (New York, N.Y.). 328: 469. PMID 20413493 DOI: 10.1126/Science.1189015 |
0.722 |
|
| 2010 |
Hillenmeyer ME, Ericson E, Davis RW, Nislow C, Koller D, Giaever G. Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action. Genome Biology. 11: R30. PMID 20226027 DOI: 10.1186/Gb-2010-11-3-R30 |
0.825 |
|
| 2010 |
Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, ... ... Giaever G, et al. The genetic landscape of a cell. Science (New York, N.Y.). 327: 425-31. PMID 20093466 DOI: 10.1126/Science.1180823 |
0.709 |
|
| 2010 |
Oh J, Fung E, Schlecht U, Davis RW, Giaever G, Onge RPS, Deutschbauer A, Nislow C. Representative results from complementation testing of “core” haploinsufficient strains. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1001140.G004 |
0.757 |
|
| 2009 |
Ammar R, Smith AM, Heisler LE, Giaever G, Nislow C. A comparative analysis of DNA barcode microarray feature size Bmc Genomics. 10: 471. PMID 19825181 DOI: 10.1186/1471-2164-10-471 |
0.662 |
|
| 2009 |
Smith AM, Heisler LE, Mellor J, Kaper F, Thompson MJ, Chee M, Roth FP, Giaever G, Nislow C. Quantitative phenotyping via deep barcode sequencing. Genome Research. 19: 1836-42. PMID 19622793 DOI: 10.1101/Gr.093955.109 |
0.696 |
|
| 2009 |
Pierce SE, Davis RW, Nislow C, Giaever G. Chemogenomic approaches to elucidation of gene function and genetic pathways. Methods in Molecular Biology (Clifton, N.J.). 548: 115-43. PMID 19521822 DOI: 10.1007/978-1-59745-540-4_7 |
0.793 |
|
| 2009 |
Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JL, Porter J, Gray CA, Andersen RJ, Giaever G, Nislow C, Andrews B, Botstein D, Graham TR, et al. A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds. Nature Biotechnology. 27: 369-77. PMID 19349972 DOI: 10.1038/Nbt.1534 |
0.742 |
|
| 2009 |
Yan Z, Berbenetz NM, Giaever G, Nislow C. Precise gene-dose alleles for chemical genetics. Genetics. 182: 623-6. PMID 19332878 DOI: 10.1534/Genetics.109.103036 |
0.706 |
|
| 2009 |
Jo WJ, Kim JH, Oh E, Jaramillo D, Holman P, Loguinov AV, Arkin AP, Nislow C, Giaever G, Vulpe CD. Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae. Bmc Genomics. 10: 130. PMID 19321002 DOI: 10.1186/1471-2164-10-130 |
0.661 |
|
| 2009 |
Hess DC, Myers CL, Huttenhower C, Hibbs MA, Hayes AP, Paw J, Clore JJ, Mendoza RM, Luis BS, Nislow C, Giaever G, Costanzo M, Troyanskaya OG, Caudy AA. Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. Plos Genetics. 5: e1000407. PMID 19300474 DOI: 10.1371/Journal.Pgen.1000407 |
0.697 |
|
| 2009 |
Giaever G, Nislow C. Knocking sense into regulatory pathways. Nature Biotechnology. 27: 149-50. PMID 19204694 DOI: 10.1038/Nbt0209-149 |
0.661 |
|
| 2009 |
Kemmer D, McHardy LM, Hoon S, Rebérioux D, Giaever G, Nislow C, Roskelley CD, Roberge M. Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. Bmc Microbiology. 9: 9. PMID 19144191 DOI: 10.1186/1471-2180-9-9 |
0.807 |
|
| 2008 |
Yu L, Lopez A, Anaflous A, El Bali B, Hamal A, Ericson E, Heisler LE, McQuibban A, Giaever G, Nislow C, Boone C, Brown GW, Bellaoui M. Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. Plos Genetics. 4: e1000284. PMID 19043571 DOI: 10.1371/Journal.Pgen.1000284 |
0.72 |
|
| 2008 |
Lehár J, Stockwell BR, Giaever G, Nislow C. Combination chemical genetics. Nature Chemical Biology. 4: 674-81. PMID 18936752 DOI: 10.1038/Nchembio.120 |
0.709 |
|
| 2008 |
Hoon S, St Onge RP, Giaever G, Nislow C. Yeast chemical genomics and drug discovery: an update. Trends in Pharmacological Sciences. 29: 499-504. PMID 18755517 DOI: 10.1016/J.Tips.2008.07.006 |
0.795 |
|
| 2008 |
Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C. Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast Plos Genetics. 4. PMID 18688276 DOI: 10.1371/Journal.Pgen.1000151 |
0.743 |
|
| 2008 |
Yan Z, Costanzo M, Heisler LE, Paw J, Kaper F, Andrews BJ, Boone C, Giaever G, Nislow C. Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers. Nature Methods. 5: 719-25. PMID 18622398 DOI: 10.1038/Nmeth.1231 |
0.699 |
|
| 2008 |
Hoon S, Smith AM, Wallace IM, Suresh S, Miranda M, Fung E, Proctor M, Shokat KM, Zhang C, Davis RW, Giaever G, St Onge RP, StOnge RP, Nislow C. An integrated platform of genomic assays reveals small-molecule bioactivities. Nature Chemical Biology. 4: 498-506. PMID 18622389 DOI: 10.1038/Nchembio.100 |
0.832 |
|
| 2008 |
Musso G, Costanzo M, Huangfu M, Smith AM, Paw J, San Luis BJ, Boone C, Giaever G, Nislow C, Emili A, Zhang Z. The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Genome Research. 18: 1092-9. PMID 18463300 DOI: 10.1101/Gr.076174.108 |
0.712 |
|
| 2008 |
Arnoldo A, Curak J, Kittanakom S, Chevelev I, Lee VT, Sahebol-Amri M, Koscik B, Ljuma L, Roy PJ, Bedalov A, Giaever G, Nislow C, Merrill AR, Merrill RA, Lory S, et al. Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen. Plos Genetics. 4: e1000005. PMID 18454192 DOI: 10.1371/Journal.Pgen.1000005 |
0.727 |
|
| 2008 |
Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G. The chemical genomic portrait of yeast: uncovering a phenotype for all genes. Science (New York, N.Y.). 320: 362-5. PMID 18420932 DOI: 10.1126/Science.1150021 |
0.816 |
|
| 2008 |
Lopez A, Parsons AB, Nislow C, Giaever G, Boone C. Chemical-genetic approaches for exploring the mode of action of natural products. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 66: 237, 239-71. PMID 18416308 DOI: 10.1007/978-3-7643-8595-8_5 |
0.756 |
|
| 2008 |
Mani R, St Onge RP, Hartman JL, Giaever G, Roth FP. Defining genetic interaction. Proceedings of the National Academy of Sciences of the United States of America. 105: 3461-6. PMID 18305163 DOI: 10.1073/Pnas.0712255105 |
0.363 |
|
| 2008 |
Jo WJ, Loguinov A, Chang M, Wintz H, Nislow C, Arkin AP, Giaever G, Vulpe CD. Identification of genes involved in the toxic response of saccharomyces cerevisiae against iron and copper overload by parallel analysis of deletion mutants Toxicological Sciences. 101: 140-151. PMID 17785683 DOI: 10.1093/Toxsci/Kfm226 |
0.684 |
|
| 2008 |
Arnoldo A, Curak J, Kittanakom S, Chevelev I, Lee VT, Sahebol-Amri M, Koscik B, Ljuma L, Roy PJ, Bedalov A, Giaever G, Nislow C, Merrill AR, Lory S, Stagljar I. Correction: Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen Plos Genetics. 4. DOI: 10.1371/Annotation/76D35829-07A2-479F-Bbc1-Cce6755B6D8C |
0.691 |
|
| 2008 |
Hoon S, Smith AM, Wallace IM, Suresh S, Miranda M, Fung E, Proctor M, Shokat KM, Zhang C, Davis RW, Giaever G, St Onge RP, Nislow C. An integrated platform of genomic assays reveals small-molecule bioactivities (Nature Chemical Biology (2008) 4, (498-506)) Nature Chemical Biology. 4: 632. DOI: 10.1038/Nchembio1008-632 |
0.775 |
|
| 2007 |
Pierce SE, Davis RW, Nislow C, Giaever G. Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures. Nature Protocols. 2: 2958-2974. PMID 18007632 DOI: 10.1038/Nprot.2007.427 |
0.776 |
|
| 2007 |
Suter B, Fetchko MJ, Imhof R, Graham CI, Stoffel-Studer I, Zbinden C, Raghavan M, Lopez L, Beneti L, Hort J, Fillingham J, Greenblatt JF, Giaever G, Nislow C, Stagljar I. Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system. Genome Research. 17: 1774-82. PMID 17989249 DOI: 10.1101/Gr.6667007 |
0.694 |
|
| 2007 |
Gassner NC, Tamble CM, Bock JE, Cotton N, White KN, Tenney K, St. Onge RP, Proctor MJ, Giaever G, Nislow C, Davis RW, Crews P, Holman TR, Lokey RS. Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay Journal of Natural Products. 70: 383-390. PMID 17291044 DOI: 10.1021/Np060555T |
0.738 |
|
| 2007 |
St Onge RP, Mani R, Oh J, Proctor M, Fung E, Davis RW, Nislow C, Roth FP, Giaever G. Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. Nature Genetics. 39: 199-206. PMID 17206143 DOI: 10.1038/Ng1948 |
0.753 |
|
| 2007 |
Doostzadeh J, Davis RW, Giaever GN, Nislow C, Langston JW. Chemical genomic profiling for identifying intracellular targets of toxicants producing Parkinson's disease. Toxicological Sciences : An Official Journal of the Society of Toxicology. 95: 182-7. PMID 17043098 DOI: 10.1093/Toxsci/Kfl131 |
0.759 |
|
| 2007 |
Nislow C, Giaever G. 17 Chemical Genomic Tools for Understanding Gene Function and Drug Action Methods in Microbiology. 36: 387-414. DOI: 10.1016/S0580-9517(06)36017-5 |
0.727 |
|
| 2006 |
Costanzo M, Giaever G, Nislow C, Andrews B. Experimental approaches to identify genetic networks. Current Opinion in Biotechnology. 17: 472-80. PMID 16962766 DOI: 10.1016/J.Copbio.2006.08.005 |
0.693 |
|
| 2006 |
Pierce SE, Fung EL, Jaramillo DF, Chu AM, Davis RW, Nislow C, Giaever G. A unique and universal molecular barcode array. Nature Methods. 3: 601-3. PMID 16862133 DOI: 10.1038/Nmeth905 |
0.711 |
|
| 2005 |
Lee W, St Onge RP, Proctor M, Flaherty P, Jordan MI, Arkin AP, Davis RW, Nislow C, Giaever G. Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. Plos Genetics. 1: e24. PMID 16121259 DOI: 10.1371/Journal.Pgen.0010024 |
0.751 |
|
| 2005 |
Wall DP, Hirsh AE, Fraser HB, Kumm J, Giaever G, Eisen MB, Feldman MW. Functional genomic analysis of the rates of protein evolution. Proceedings of the National Academy of Sciences of the United States of America. 102: 5483-8. PMID 15800036 DOI: 10.1073/Pnas.0501761102 |
0.312 |
|
| 2005 |
Deutschbauer AM, Jaramillo DF, Proctor M, Kumm J, Hillenmeyer ME, Davis RW, Nislow C, Giaever G. Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics. 169: 1915-25. PMID 15716499 DOI: 10.1534/Genetics.104.036871 |
0.813 |
|
| 2004 |
Fraser HB, Hirsh AE, Giaever G, Kumm J, Eisen MB. Noise minimization in eukaryotic gene expression. Plos Biology. 2: e137. PMID 15124029 DOI: 10.1371/Journal.Pbio.0020137 |
0.32 |
|
| 2004 |
Giaever G, Flaherty P, Kumm J, Proctor M, Nislow C, Jaramillo DF, Chu AM, Jordan MI, Arkin AP, Davis RW. Chemogenomic profiling: identifying the functional interactions of small molecules in yeast. Proceedings of the National Academy of Sciences of the United States of America. 101: 793-8. PMID 14718668 DOI: 10.1073/Pnas.0307490100 |
0.776 |
|
| 2003 |
Giaever G. A chemical genomics approach to understanding drug action. Trends in Pharmacological Sciences. 24: 444-6. PMID 12967766 DOI: 10.1016/S0165-6147(03)00225-6 |
0.448 |
|
| 2003 |
Nislow C, Giaever G. "Chemogenomics: tools for protein families" and "Chemical genomics: chemical and biological integration". Pharmacogenomics. 4: 15-8. PMID 12517281 DOI: 10.1517/Phgs.4.1.15.22579 |
0.718 |
|
| 2002 |
Giaever G, Chu AM, Ni L, Connelly C, Riles L, Véronneau S, Dow S, Lucau-Danila A, Anderson K, André B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, et al. Functional profiling of the Saccharomyces cerevisiae genome. Nature. 418: 387-91. PMID 12140549 DOI: 10.1038/Nature00935 |
0.801 |
|
| 2002 |
Steinmetz LM, Scharfe C, Deutschbauer AM, Mokranjac D, Herman ZS, Jones T, Chu AM, Giaever G, Prokisch H, Oefner PJ, Davis RW. Systematic screen for human disease genes in yeast. Nature Genetics. 31: 400-4. PMID 12134146 DOI: 10.1038/Ng929 |
0.761 |
|
| 2002 |
Birrell GW, Brown JA, Wu HI, Giaever G, Chu AM, Davis RW, Brown JM. Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proceedings of the National Academy of Sciences of the United States of America. 99: 8778-83. PMID 12077312 DOI: 10.1073/Pnas.132275199 |
0.513 |
|
| 2001 |
Birrell GW, Giaever G, Chu AM, Davis RW, Brown JM. A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 98: 12608-13. PMID 11606770 DOI: 10.1073/Pnas.231366398 |
0.576 |
|
| 1999 |
Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, ... ... Giaever G, et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science (New York, N.Y.). 285: 901-6. PMID 10436161 DOI: 10.1126/Science.285.5429.901 |
0.778 |
|
| 1999 |
Giaever G, Shoemaker DD, Jones TW, Liang H, Winzeler EA, Astromoff A, Davis RW. Genomic profiling of drug sensitivities via induced haploinsufficiency. Nature Genetics. 21: 278-83. PMID 10080179 DOI: 10.1038/6791 |
0.685 |
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