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James A. Spudich - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
myosin
Website:
http://spudlab.stanford.edu/

216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. The Journal of Biological Chemistry. PMID 31582565 DOI: 10.1074/jbc.RA119.010563  0.32
2019 Adhikari AS, Trivedi DV, Sarkar SS, Song D, Kooiker KB, Bernstein D, Spudich JA, Ruppel KM. β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity. Nature Communications. 10: 2685. PMID 31213605 DOI: 10.1038/s41467-019-10555-9  0.32
2018 Wilkinson AW, Diep J, Dai S, Liu S, Ooi YS, Song D, Li TM, Horton JR, Zhang X, Liu C, Trivedi DV, Ruppel KM, Vilches-Moure JG, Casey KM, Mak J, ... ... Spudich JA, et al. SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature. PMID 30626964 DOI: 10.1038/s41586-018-0821-8  0.32
2018 Anderson RL, Trivedi DV, Sarkar SS, Henze M, Ma W, Gong H, Rogers CS, Gorham JM, Wong FL, Morck MM, Seidman JG, Ruppel KM, Irving TC, Cooke R, Green EM, ... Spudich JA, et al. Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers. Proceedings of the National Academy of Sciences of the United States of America. PMID 30104387 DOI: 10.1073/pnas.1809540115  0.32
2018 Liu C, Kawana M, Song D, Ruppel KM, Spudich JA. Controlling load-dependent kinetics of β-cardiac myosin at the single-molecule level. Nature Structural & Molecular Biology. PMID 29867217 DOI: 10.1038/s41594-018-0069-x  0.32
2017 Trivedi DV, Adhikari AS, Sarkar SS, Ruppel KM, Spudich JA. Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light. Biophysical Reviews. PMID 28717924 DOI: 10.1007/s12551-017-0274-6  0.32
2017 Nag S, Trivedi DV, Sarkar SS, Adhikari AS, Sunitha MS, Sutton S, Ruppel KM, Spudich JA. The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations. Nature Structural & Molecular Biology. PMID 28481356 DOI: 10.1038/nsmb.3408  0.32
2017 Kawana M, Sarkar SS, Sutton S, Ruppel KM, Spudich JA. Biophysical properties of human β-cardiac myosin with converter mutations that cause hypertrophic cardiomyopathy. Science Advances. 3: e1601959. PMID 28246639 DOI: 10.1126/sciadv.1601959  0.32
2016 Adhikari AS, Kooiker KB, Sarkar SS, Liu C, Bernstein D, Spudich JA, Ruppel KM. Early-Onset Hypertrophic Cardiomyopathy Mutations Significantly Increase the Velocity, Force, and Actin-Activated ATPase Activity of Human β-Cardiac Myosin. Cell Reports. 17: 2857-2864. PMID 27974200 DOI: 10.1016/j.celrep.2016.11.040  0.32
2016 Homburger JR, Green EM, Caleshu C, Sunitha MS, Taylor RE, Ruppel KM, Metpally RP, Colan SD, Michels M, Day SM, Olivotto I, Bustamante CD, Dewey FE, Ho CY, Spudich JA, et al. Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247418 DOI: 10.1073/pnas.1606950113  1
2016 Spudich JA, Aksel T, Bartholomew SR, Nag S, Kawana M, Yu EC, Sarkar SS, Sung J, Sommese RF, Sutton S, Cho C, Adhikari AS, Taylor R, Liu C, Trivedi D, et al. Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin. The Journal of Experimental Biology. 219: 161-7. PMID 26792326 DOI: 10.1242/jeb.125930  1
2015 Nag S, Sommese RF, Ujfalusi Z, Combs A, Langer S, Sutton S, Leinwand LA, Geeves MA, Ruppel KM, Spudich JA. Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function. Science Advances. 1: e1500511. PMID 26601291 DOI: 10.1126/sciadv.1500511  0.64
2015 Mortensen KI, Sung J, Flyvbjerg H, Spudich JA. Optimized measurements of separations and angles between intra-molecular fluorescent markers. Nature Communications. 6: 8621. PMID 26509412 DOI: 10.1038/ncomms9621  0.48
2015 Pan S, Sommese RF, Sallam KI, Nag S, Sutton S, Miller SM, Spudich JA, Ruppel KM, Ashley EA. Establishing disease causality for a novel gene variant in familial dilated cardiomyopathy using a functional in-vitro assay of regulated thin filaments and human cardiac myosin. Bmc Medical Genetics. 16: 97. PMID 26498512 DOI: 10.1186/s12881-015-0243-5  1
2015 Manor U, Bartholomew S, Golani G, Christenson E, Kozlov M, Higgs H, Spudich J, Lippincott-Schwartz J. A mitochondria-anchored isoform of the actin-nucleating Spire protein regulates mitochondrial division. Elife. 4. PMID 26305500 DOI: 10.7554/eLife.08828  1
2015 Sung J, Nag S, Mortensen KI, Vestergaard CL, Sutton S, Ruppel K, Flyvbjerg H, Spudich JA. Harmonic force spectroscopy measures load-dependent kinetics of individual human β-cardiac myosin molecules. Nature Communications. 6: 7931. PMID 26239258 DOI: 10.1038/ncomms8931  0.48
2015 Hariadi RF, Sommese RF, Adhikari AS, Taylor RE, Sutton S, Spudich JA, Sivaramakrishnan S. Mechanical coordination in motor ensembles revealed using engineered artificial myosin filaments. Nature Nanotechnology. PMID 26149240 DOI: 10.1038/nnano.2015.132  1
2015 Aksel T, Choe Yu E, Sutton S, Ruppel KM, Spudich JA. Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector. Cell Reports. 11: 910-20. PMID 25937279 DOI: 10.1016/j.celrep.2015.04.006  1
2015 Spudich JA. The myosin mesa and a possible unifying hypothesis for the molecular basis of human hypertrophic cardiomyopathy. Biochemical Society Transactions. 43: 64-72. PMID 25619247 DOI: 10.1042/BST20140324  1
2015 Gupte TM, Haque F, Gangadharan B, Sunitha MS, Mukherjee S, Anandhan S, Rani DS, Mukundan N, Jambekar A, Thangaraj K, Sowdhamini R, Sommese RF, Nag S, Spudich JA, Mercer JA. Mechanistic heterogeneity in contractile properties of α-tropomyosin (TPM1) mutants associated with inherited cardiomyopathies. The Journal of Biological Chemistry. 290: 7003-15. PMID 25548289 DOI: 10.1074/jbc.M114.596676  1
2015 Sung J, Nag S, Mortensen KI, Vestergaard CL, Sutton S, Ruppel K, Flyvbjerg H, Spudich JA. Harmonic force spectroscopy measures load-dependent kinetics of individual human β-cardiac myosin molecules Nature Communications. 6. DOI: 10.1038/ncomms8931  1
2014 Mendez D, Lane TJ, Sung J, Sellberg J, Levard C, Watkins H, Cohen AE, Soltis M, Sutton S, Spudich J, Pande V, Ratner D, Doniach S. Observation of correlated X-ray scattering at atomic resolution. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130315. PMID 24914148 DOI: 10.1098/rstb.2013.0315  1
2014 Spudich JA. Hypertrophic and dilated cardiomyopathy: four decades of basic research on muscle lead to potential therapeutic approaches to these devastating genetic diseases. Biophysical Journal. 106: 1236-49. PMID 24655499 DOI: 10.1016/j.bpj.2014.02.011  1
2013 Sommese RF, Nag S, Sutton S, Miller SM, Spudich JA, Ruppel KM. Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin. Plos One. 8: e83403. PMID 24367593 DOI: 10.1371/journal.pone.0083403  1
2013 Spudich J. Memories of Hugh E. Huxley (1924-2013) Molecular Biology of the Cell. 24: 2769-2771. PMID 24030511  1
2013 Sommese RF, Sung J, Nag S, Sutton S, Deacon JC, Choe E, Leinwand LA, Ruppel K, Spudich JA. Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function. Proceedings of the National Academy of Sciences of the United States of America. 110: 12607-12. PMID 23798412 DOI: 10.1073/pnas.1309493110  1
2013 Elting MW, Leslie SR, Churchman LS, Korlach J, McFaul CM, Leith JS, Levene MJ, Cohen AE, Spudich JA. Single-molecule fluorescence imaging of processive myosin with enhanced background suppression using linear zero-mode waveguides (ZMWs) and convex lens induced confinement (CLIC). Optics Express. 21: 1189-202. PMID 23389011 DOI: 10.1364/OE.21.001189  1
2012 Elting MW, Spudich JA. Future challenges in single-molecule fluorescence and laser trap approaches to studies of molecular motors. Developmental Cell. 23: 1084-91. PMID 23237942 DOI: 10.1016/j.devcel.2012.10.002  1
2012 Margaret Sunitha S, Mercer JA, Spudich JA, Sowdhamini R. Integrative structural modelling of the cardiac thin filament: energetics at the interface and conservation patterns reveal a spotlight on period 2 of tropomyosin. Bioinformatics and Biology Insights. 6: 203-23. PMID 23071391 DOI: 10.4137/BBI.S9798  1
2012 Spudich JA. One path to understanding energy transduction in biological systems. Nature Medicine. 18: 1478-82. PMID 23042356 DOI: 10.1038/nm.2924  1
2012 Chuan P, Sivaramakrishnan S, Ashley EA, Spudich JA. Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy. Biophysical Journal. 102: 2782-90. PMID 22735528 DOI: 10.1016/j.bpj.2012.04.049  1
2012 Hartman MA, Spudich JA. The myosin superfamily at a glance. Journal of Cell Science. 125: 1627-32. PMID 22566666 DOI: 10.1242/jcs.094300  1
2012 Syamaladevi DP, Spudich JA, Sowdhamini R. Structural and functional insights on the Myosin superfamily. Bioinformatics and Biology Insights. 6: 11-21. PMID 22399849 DOI: 10.4137/BBI.S8451  1
2012 Churchman LS, Spudich JA. Single-molecule high-resolution colocalization of single probes. Cold Spring Harbor Protocols. 2012: 242-5. PMID 22301661 DOI: 10.1101/pdb.prot067926  1
2012 Churchman LS, Spudich JA. Colocalization of fluorescent probes: accurate and precise registration with nanometer resolution. Cold Spring Harbor Protocols. 2012: 141-9. PMID 22301660 DOI: 10.1101/pdb.top067918  1
2012 Sheetz M, Spudich J, Vale R. The lasker awards: Motors take centre stage Nature Cell Biology. 14: 1113. DOI: 10.1038/ncb2618  1
2011 Dunn AR, Spudich JA. Single-molecule gold-nanoparticle tracking. Cold Spring Harbor Protocols. 2011: 1498-506. PMID 22135665 DOI: 10.1101/pdb.prot066977  1
2011 Sivaramakrishnan S, Spudich JA. Systematic control of protein interaction using a modular ER/K α-helix linker. Proceedings of the National Academy of Sciences of the United States of America. 108: 20467-72. PMID 22123984 DOI: 10.1073/pnas.1116066108  1
2011 Spudich JA, Rice SE, Rock RS, Purcell TJ, Warrick HM. The optical trapping dumbbell assay for nonprocessive motors or motors that turn around filaments. Cold Spring Harbor Protocols. 2011: 1372-4. PMID 22046050 DOI: 10.1101/pdb.prot066688  1
2011 Spudich JA, Rice SE, Rock RS, Purcell TJ, Warrick HM. Attachment of anti-GFP antibodies to microspheres for optical trapping experiments. Cold Spring Harbor Protocols. 2011: 1370-1. PMID 22046049 DOI: 10.1101/pdb.prot066670  1
2011 Spudich JA, Rice SE, Rock RS, Purcell TJ, Warrick HM. Optical traps to study properties of molecular motors. Cold Spring Harbor Protocols. 2011: 1305-18. PMID 22046048 DOI: 10.1101/pdb.top066662  1
2011 Spudich JA. Molecular motors: forty years of interdisciplinary research. Molecular Biology of the Cell. 22: 3936-9. PMID 22039067 DOI: 10.1091/mbc.E11-05-0447  1
2011 Hartman MA, Finan D, Sivaramakrishnan S, Spudich JA. Principles of unconventional myosin function and targeting. Annual Review of Cell and Developmental Biology. 27: 133-55. PMID 21639800 DOI: 10.1146/annurev-cellbio-100809-151502  1
2011 Spudich JA. Biochemistry. Molecular motors, beauty in complexity. Science (New York, N.Y.). 331: 1143-4. PMID 21385703 DOI: 10.1126/science.1203978  1
2011 Finan D, Hartman MA, Spudich JA. Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: 5566-71. PMID 21368190 DOI: 10.1073/pnas.1101415108  1
2011 Elting MW, Bryant Z, Liao JC, Spudich JA. Detailed tuning of structure and intramolecular communication are dispensable for processive motion of myosin VI. Biophysical Journal. 100: 430-9. PMID 21244839 DOI: 10.1016/j.bpj.2010.11.045  1
2011 Purcell TJ, Naber N, Franks-Skiba K, Dunn AR, Eldred CC, Berger CL, Málnási-Csizmadia A, Spudich JA, Swank DM, Pate E, Cooke R. Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency. Journal of Molecular Biology. 407: 79-91. PMID 21185304 DOI: 10.1016/j.jmb.2010.11.053  1
2011 Chuan P, Spudich JA, Dunn AR. Robust mechanosensing and tension generation by myosin VI. Journal of Molecular Biology. 405: 105-12. PMID 20970430 DOI: 10.1016/j.jmb.2010.10.010  1
2010 Sommese RF, Sivaramakrishnan S, Baldwin RL, Spudich JA. Helicity of short E-R/K peptides. Protein Science : a Publication of the Protein Society. 19: 2001-5. PMID 20669185 DOI: 10.1002/pro.469  1
2010 Sung J, Sivaramakrishnan S, Dunn AR, Spudich JA. Single-molecule dual-beam optical trap analysis of protein structure and function. Methods in Enzymology. 475: 321-75. PMID 20627164 DOI: 10.1016/S0076-6879(10)75014-X  1
2010 Uehara R, Goshima G, Mabuchi I, Vale RD, Spudich JA, Griffis ER. Determinants of myosin II cortical localization during cytokinesis. Current Biology : Cb. 20: 1080-5. PMID 20541410 DOI: 10.1016/j.cub.2010.04.058  1
2010 Dunn AR, Chuan P, Bryant Z, Spudich JA. Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing. Proceedings of the National Academy of Sciences of the United States of America. 107: 7746-50. PMID 20385849 DOI: 10.1073/pnas.1002430107  1
2010 Mortensen KI, Churchman LS, Spudich JA, Flyvbjerg H. Optimized localization analysis for single-molecule tracking and super-resolution microscopy. Nature Methods. 7: 377-81. PMID 20364147 DOI: 10.1038/nmeth.1447  1
2010 Spudich JA, Sivaramakrishnan S. Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis. Nature Reviews. Molecular Cell Biology. 11: 128-37. PMID 20094053 DOI: 10.1038/nrm2833  1
2010 Resnicow DI, Deacon JC, Warrick HM, Spudich JA, Leinwand LA. Functional diversity among a family of human skeletal muscle myosin motors. Proceedings of the National Academy of Sciences of the United States of America. 107: 1053-8. PMID 20080549 DOI: 10.1073/pnas.0913527107  1
2010 Resnicow DI, Deacon JC, Warrick HM, Spudich JA, Leinwand LA. Functional diversity among a family of human skeletal muscle myosin motors (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 3 (1053-1058) DOI: 10.1073/pnas.0913527107) Proceedings of the National Academy of Sciences of the United States of America. 107: 10765. DOI: 10.1073/pnas.1005980107  1
2009 Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA. Insights into human beta-cardiac myosin function from single molecule and single cell studies. Journal of Cardiovascular Translational Research. 2: 426-40. PMID 20560001 DOI: 10.1007/s12265-009-9129-2  1
2009 Sivaramakrishnan S, Sung J, Ali M, Doniach S, Flyvbjerg H, Spudich JA. Combining single-molecule optical trapping and small-angle x-ray scattering measurements to compute the persistence length of a protein ER/K alpha-helix. Biophysical Journal. 97: 2993-9. PMID 19948129 DOI: 10.1016/j.bpj.2009.09.009  1
2009 Sivaramakrishnan S, Spudich JA. Coupled myosin VI motors facilitate unidirectional movement on an F-actin network. The Journal of Cell Biology. 187: 53-60. PMID 19786577 DOI: 10.1083/jcb.200906133  1
2009 Vale RD, Spudich JA, Griffis ER. Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells. The Journal of Cell Biology. 186: 727-38. PMID 19720876 DOI: 10.1083/jcb.200902083  1
2009 Liao JC, Elting MW, Delp SL, Spudich JA, Bryant Z. Engineered myosin VI motors reveal minimal structural determinants of directionality and processivity. Journal of Molecular Biology. 392: 862-7. PMID 19631216 DOI: 10.1016/j.jmb.2009.07.046  1
2009 Pierobon P, Achouri S, Courty S, Dunn AR, Spudich JA, Dahan M, Cappello G. Velocity, processivity, and individual steps of single myosin V molecules in live cells. Biophysical Journal. 96: 4268-75. PMID 19450497 DOI: 10.1016/j.bpj.2009.02.045  1
2008 Spudich JA. Dynamic organization of gene loci and transcription compartments in the cell nucleus. Biophysical Journal. 95: 5003-4. PMID 18805930 DOI: 10.1529/biophysj.108.139196  1
2008 Sivaramakrishnan S, Spink BJ, Sim AY, Doniach S, Spudich JA. Dynamic charge interactions create surprising rigidity in the ER/K alpha-helical protein motif. Proceedings of the National Academy of Sciences of the United States of America. 105: 13356-61. PMID 18768817 DOI: 10.1073/pnas.0806256105  1
2008 Spink BJ, Sivaramakrishnan S, Lipfert J, Doniach S, Spudich JA. Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI. Nature Structural & Molecular Biology. 15: 591-7. PMID 18511944 DOI: 10.1038/nsmb.1429  1
2008 Spudich JA. Molecular motors: a surprising twist in myosin VI translocation. Current Biology : Cb. 18: R68-70. PMID 18211842 DOI: 10.1016/j.cub.2007.11.025  1
2007 Tang S, Liao JC, Dunn AR, Altman RB, Spudich JA, Schmidt JP. Predicting allosteric communication in myosin via a pathway of conserved residues. Journal of Molecular Biology. 373: 1361-73. PMID 17900617 DOI: 10.1016/j.jmb.2007.08.059  1
2007 Altman D, Goswami D, Hasson T, Spudich JA, Mayor S. Precise positioning of myosin VI on endocytic vesicles in vivo. Plos Biology. 5: e210. PMID 17683200 DOI: 10.1371/journal.pbio.0050210  1
2007 Chen Q, Lakshmikanth GS, Spudich JA, De Lozanne A. The localization of inner centromeric protein (INCENP) at the cleavage furrow is dependent on Kif12 and involves interactions of the N terminus of INCENP with the actin cytoskeleton. Molecular Biology of the Cell. 18: 3366-74. PMID 17567958 DOI: 10.1091/mbc.E06-10-0895  1
2007 Geething NC, Spudich JA. Identification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilin. The Journal of Biological Chemistry. 282: 21518-28. PMID 17513864 DOI: 10.1074/jbc.M701932200  1
2007 Liao JC, Spudich JA, Parker D, Delp SL. Extending the absorbing boundary method to fit dwell-time distributions of molecular motors with complex kinetic pathways. Proceedings of the National Academy of Sciences of the United States of America. 104: 3171-6. PMID 17360624 DOI: 10.1073/pnas.0611519104  1
2007 Dunn AR, Spudich JA. Dynamics of the unbound head during myosin V processive translocation. Nature Structural & Molecular Biology. 14: 246-8. PMID 17293871 DOI: 10.1038/nsmb1206  1
2007 Bryant Z, Altman D, Spudich JA. The power stroke of myosin VI and the basis of reverse directionality. Proceedings of the National Academy of Sciences of the United States of America. 104: 772-7. PMID 17182734 DOI: 10.1073/pnas.0610144104  1
2006 Dean SO, Spudich JA. Rho kinase's role in myosin recruitment to the equatorial cortex of mitotic Drosophila S2 cells is for myosin regulatory light chain phosphorylation. Plos One. 1: e131. PMID 17205135 DOI: 10.1371/journal.pone.0000131  1
2006 Spudich JA. Molecular motors take tension in stride. Cell. 126: 242-4. PMID 16873054 DOI: 10.1016/j.cell.2006.07.009  1
2006 Churchman LS, Flyvbjerg H, Spudich JA. A non-Gaussian distribution quantifies distances measured with fluorescence localization techniques. Biophysical Journal. 90: 668-71. PMID 16258038 DOI: 10.1529/biophysj.105.065599  1
2005 Dean SO, Rogers SL, Stuurman N, Vale RD, Spudich JA. Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 13473-8. PMID 16174742 DOI: 10.1073/pnas.0506810102  1
2005 Purcell TJ, Sweeney HL, Spudich JA. A force-dependent state controls the coordination of processive myosin V. Proceedings of the National Academy of Sciences of the United States of America. 102: 13873-8. PMID 16150709 DOI: 10.1073/pnas.0506441102  1
2005 Rock RS, Ramamurthy B, Dunn AR, Beccafico S, Rami BR, Morris C, Spink BJ, Franzini-Armstrong C, Spudich JA, Sweeney HL. A flexible domain is essential for the large step size and processivity of myosin VI. Molecular Cell. 17: 603-9. PMID 15721263 DOI: 10.1016/j.molcel.2005.01.015  1
2005 Churchman LS, Okten Z, Rock RS, Dawson JF, Spudich JA. Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time. Proceedings of the National Academy of Sciences of the United States of America. 102: 1419-23. PMID 15668396 DOI: 10.1073/pnas.0409487102  1
2004 Lakshmikanth GS, Warrick HM, Spudich JA. A mitotic kinesin-like protein required for normal karyokinesis, myosin localization to the furrow, and cytokinesis in Dictyostelium. Proceedings of the National Academy of Sciences of the United States of America. 101: 16519-24. PMID 15546981 DOI: 10.1073/pnas.0407304101  1
2004 Spudich JA. Two important polymers cross paths. Proceedings of the National Academy of Sciences of the United States of America. 101: 15825-6. PMID 15522968 DOI: 10.1073/pnas.0406932101  1
2004 Hostetter D, Rice S, Dean S, Altman D, McMahon PM, Sutton S, Tripathy A, Spudich JA. Dictyostelium myosin bipolar thick filament formation: importance of charge and specific domains of the myosin rod. Plos Biology. 2: e356. PMID 15492777 DOI: 10.1371/journal.pbio.0020356  1
2004 Okten Z, Churchman LS, Rock RS, Spudich JA. Myosin VI walks hand-over-hand along actin. Nature Structural & Molecular Biology. 11: 884-7. PMID 15286724 DOI: 10.1038/nsmb815  1
2004 Robinson DN, Spudich JA. Mechanics and regulation of cytokinesis. Current Opinion in Cell Biology. 16: 182-8. PMID 15196562 DOI: 10.1016/j.ceb.2004.02.002  1
2004 Altman D, Sweeney HL, Spudich JA. The mechanism of myosin VI translocation and its load-induced anchoring. Cell. 116: 737-49. PMID 15006355 DOI: 10.1016/S0092-8674(04)00211-9  1
2003 Rice SE, Purcell TJ, Spudich JA. Building and using optical traps to study properties of molecular motors. Methods in Enzymology. 361: 112-33. PMID 12624909 DOI: 10.1016/S0076-6879(03)61008-6  1
2003 Dawson JF, Sablin EP, Spudich JA, Fletterick RJ. Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing. The Journal of Biological Chemistry. 278: 1229-38. PMID 12356759 DOI: 10.1074/jbc.M209160200  1
2003 Rock RS, Purcell TJ, Spudich JA. Mechanics of Unconventional Myosins Enzymes. 23: 55-86. DOI: 10.1016/S1874-6047(04)80003-9  1
2002 Purcell TJ, Morris C, Spudich JA, Sweeney HL. Role of the lever arm in the processive stepping of myosin V. Proceedings of the National Academy of Sciences of the United States of America. 99: 14159-64. PMID 12386339 DOI: 10.1073/pnas.182539599  1
2002 Sablin EP, Dawson JF, VanLoock MS, Spudich JA, Egelman EH, Fletterick RJ. How does ATP hydrolysis control actin's associations? Proceedings of the National Academy of Sciences of the United States of America. 99: 10945-7. PMID 12167670 DOI: 10.1073/pnas.152329899  1
2002 Liang W, Licate L, Warrick H, Spudich J, Egelhoff T. Differential localization in cells of myosin II heavy chain kinases during cytokinesis and polarized migration Bmc Cell Biology [Electronic Resource]. 3: 19. PMID 12139770  1
2002 Robinson DN, Cavet G, Warrick HM, Spudich JA. Quantitation of the distribution and flux of myosin-II during cytokinesis. Bmc Cell Biology. 3: 4. PMID 11860600 DOI: 10.1186/1471-2121-3-4  1
2002 Robinson DN, Ocon SS, Rock RS, Spudich JA. Dynacortin is a novel actin bundling protein that localizes to dynamic actin structures. The Journal of Biological Chemistry. 277: 9088-95. PMID 11782490 DOI: 10.1074/jbc.M112144200  1
2002 Spudich JA, Rock RS. A crossbridge too far. Nature Cell Biology. 4: E8-10. PMID 11780133 DOI: 10.1038/ncb0102-e8  1
2002 Liang W, Licate LS, Warrick HM, Spudich JA, Egelhoff TT. Differential localization in cells myosin II heavy chain kinases during cytokinesis and polarized migration Bmc Cell Biology. 3. DOI: 10.1186/1471-2121-3-19  1
2001 Rock RS, Rice SE, Wells AL, Purcell TJ, Spudich JA, Sweeney HL. Myosin VI is a processive motor with a large step size. Proceedings of the National Academy of Sciences of the United States of America. 98: 13655-9. PMID 11707568 DOI: 10.1073/pnas.191512398  1
2001 Spudich JA. The myosin swinging cross-bridge model. Nature Reviews. Molecular Cell Biology. 2: 387-92. PMID 11331913 DOI: 10.1038/35073086  1
2001 Shih WM, Spudich JA. The myosin relay helix to converter interface remains intact throughout the actomyosin ATPase cycle. The Journal of Biological Chemistry. 276: 19491-4. PMID 11278776 DOI: 10.1074/jbc.M010887200  1
2001 Murphy CT, Rock RS, Spudich JA. A myosin II mutation uncouples ATPase activity from motility and shortens step size. Nature Cell Biology. 3: 311-5. PMID 11231583 DOI: 10.1038/35060110  1
2000 Rock RS, Rief M, Mehta AD, Spudich JA. In vitro assays of processive myosin motors. Methods (San Diego, Calif.). 22: 373-81. PMID 11133243 DOI: 10.1006/meth.2000.1089  1
2000 Shih WM, Gryczynski Z, Lakowicz JR, Spudich JA. A FRET-based sensor reveals large ATP hydrolysis-induced conformational changes and three distinct states of the molecular motor myosin. Cell. 102: 683-94. PMID 11007486  1
2000 Murphy CT, Spudich JA. Variable surface loops and myosin activity: accessories to a motor. Journal of Muscle Research and Cell Motility. 21: 139-51. PMID 10961838 DOI: 10.1023/A:1005610007209  1
2000 Robinson DN, Spudich JA. Dynacortin, a genetic link between equatorial contractility and global shape control discovered by library complementation of a Dictyostelium discoideum cytokinesis mutant. The Journal of Cell Biology. 150: 823-38. PMID 10953006 DOI: 10.1083/jcb.150.4.823  1
2000 Rief M, Rock RS, Mehta AD, Mooseker MS, Cheney RE, Spudich JA. Myosin-V stepping kinetics: a molecular model for processivity. Proceedings of the National Academy of Sciences of the United States of America. 97: 9482-6. PMID 10944217  1
2000 Robinson DN, Spudich JA. Towards a molecular understanding of cytokinesis. Trends in Cell Biology. 10: 228-37. PMID 10802538 DOI: 10.1016/S0962-8924(00)01747-5  1
2000 Nock S, Liang W, Warrick HM, Spudich JA. Mutational analysis of phosphorylation sites in the Dictyostelium myosin II tail: disruption of myosin function by a single charge change. Febs Letters. 466: 267-72. PMID 10682841 DOI: 10.1016/S0014-5793(99)01796-2  1
1999 Liang W, Warrick HM, Spudich JA. A structural model for phosphorylation control of Dictyostelium myosin II thick filament assembly. The Journal of Cell Biology. 147: 1039-48. PMID 10579723 DOI: 10.1083/jcb.147.5.1039  1
1999 Mehta AD, Rock RS, Rief M, Spudich JA, Mooseker MS, Cheney RE. Myosin-V is a processive actin-based motor. Nature. 400: 590-3. PMID 10448864 DOI: 10.1038/23072  1
1999 Mehta AD, Rief M, Spudich JA. Biomechanics, one molecule at a time. The Journal of Biological Chemistry. 274: 14517-20. PMID 10329637 DOI: 10.1074/jbc.274.21.14517  1
1999 Murphy CT, Spudich JA. The sequence of the myosin 50-20K loop affects Myosin's affinity for actin throughout the actin-myosin ATPase cycle and its maximum ATPase activity. Biochemistry. 38: 3785-92. PMID 10090768 DOI: 10.1021/bi9826815  1
1999 Goodson HV, Warrick HM, Spudich JA. Specialized conservation of surface loops of myosin: evidence that loops are involved in determining functional characteristics. Journal of Molecular Biology. 287: 173-85. PMID 10074415 DOI: 10.1006/jmbi.1999.2565  1
1999 Mehta AD, Rief M, Spudich JA, Smith DA, Simmons RM. Single-molecule biomechanics with optical methods. Science (New York, N.Y.). 283: 1689-95. PMID 10073927 DOI: 10.1126/science.283.5408.1689  1
1999 Mehta AD, Spudich JA. Single myosin molecule mechanics Advances in Structural Biology. 5: 229-270. DOI: 10.1016/S1064-6000(98)80013-6  1
1998 Zang JH, Spudich JA. Myosin II localization during cytokinesis occurs by a mechanism that does not require its motor domain. Proceedings of the National Academy of Sciences of the United States of America. 95: 13652-7. PMID 9811855 DOI: 10.1073/pnas.95.23.13652  1
1998 Silveira LA, Smith JL, Tan JL, Spudich JA. MLCK-A, an unconventional myosin light chain kinase from Dictyostelium, is activated by a cGMP-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 95: 13000-5. PMID 9789030 DOI: 10.1073/pnas.95.22.13000  1
1998 Liang W, Spudich JA. Nucleotide-dependent conformational change near the fulcrum region in Dictyostelium myosin II. Proceedings of the National Academy of Sciences of the United States of America. 95: 12844-7. PMID 9789002 DOI: 10.1073/pnas.95.22.12844  1
1998 Mehta AD, Finer JT, Spudich JA. Use of optical traps in single-molecule study of nonprocessive biological motors. Methods in Enzymology. 298: 436-59. PMID 9751902 DOI: 10.1016/S0076-6879(98)98039-9  1
1998 Mehta AD, Pullen KA, Spudich JA. Single molecule biochemistry using optical tweezers. Febs Letters. 430: 23-7. PMID 9678588 DOI: 10.1016/S0014-5793(98)00594-8  1
1998 Friedman AL, Geeves MA, Manstein DJ, Spudich JA. Kinetic characterization of myosin head fragments with long-lived myosin.ATP states. Biochemistry. 37: 9679-87. PMID 9657680 DOI: 10.1021/bi973143f  1
1998 Moores SL, Spudich JA. Conditional loss-of-myosin-II-function mutants reveal a position in the tail that is critical for filament nucleation. Molecular Cell. 1: 1043-50. PMID 9651587  1
1998 Murphy CT, Spudich JA. Dictyostelium myosin 25-50K loop substitutions specifically affect ADP release rates. Biochemistry. 37: 6738-44. PMID 9578557 DOI: 10.1021/bi972903j  1
1998 Mehta AD, Finer JT, Spudich JA. Reflections of a lucid dreamer: optical trap design considerations. Methods in Cell Biology. 55: 47-69. PMID 9352511  1
1997 Zang JH, Cavet G, Sabry JH, Wagner P, Moores SL, Spudich JA. On the role of myosin-II in cytokinesis: division of Dictyostelium cells under adhesive and nonadhesive conditions. Molecular Biology of the Cell. 8: 2617-29. PMID 9398680  1
1997 Sabry JH, Moores SL, Ryan S, Zang JH, Spudich JA. Myosin heavy chain phosphorylation sites regulate myosin localization during cytokinesis in live cells. Molecular Biology of the Cell. 8: 2605-15. PMID 9398679  1
1997 Patterson B, Ruppel KM, Wu Y, Spudich JA. Cold-sensitive mutants G680V and G691C of Dictyostelium myosin II confer dramatically different biochemical defects. The Journal of Biological Chemistry. 272: 27612-7. PMID 9346898 DOI: 10.1074/jbc.272.44.27612  1
1997 Nock S, Spudich JA, Wagner P. Reversible, site-specific immobilization of polyarginine-tagged fusion proteins on mica surfaces. Febs Letters. 414: 233-8. PMID 9315692 DOI: 10.1016/S0014-5793(97)01040-5  1
1997 Wagner P, Nock S, Spudich JA, Volkmuth WD, Chu S, Cicero RL, Wade CP, Linford MR, Chidsey CE. Bioreactive self-assembled monolayers on hydrogen-passivated Si(111) as a new class of atomically flat substrates for biological scanning probe microscopy. Journal of Structural Biology. 119: 189-201. PMID 9245759 DOI: 10.1006/jsbi.1997.3881  1
1997 Mehta AD, Finer JT, Spudich JA. Detection of single-molecule interactions using correlated thermal diffusion. Proceedings of the National Academy of Sciences of the United States of America. 94: 7927-31. PMID 9223289 DOI: 10.1073/pnas.94.15.7927  1
1997 Giese KC, Spudich JA. Phenotypically selected mutations in myosin's actin binding domain demonstrate intermolecular contacts important for motor function. Biochemistry. 36: 8465-73. PMID 9214290 DOI: 10.1021/bi963141f  1
1997 Spudich JA, Mehta A. Single myosin molecule mechanics: Nanometer steps, piconewton forces, millisecond kinetics, and stiffness of elastic elements measured with a dual-beam laser trap Faseb Journal. 11: A855.  1
1996 Ruppel KM, Spudich JA. Structure-function analysis of the motor domain of myosin. Annual Review of Cell and Developmental Biology. 12: 543-73. PMID 8970737 DOI: 10.1146/annurev.cellbio.12.1.543  1
1996 Smith JL, Silveira LA, Spudich JA. Activation of Dictyostelium myosin light chain kinase A by phosphorylation of Thr166. The Embo Journal. 15: 6075-83. PMID 8947030  1
1996 Smith JL, Silveira LA, Spudich JA. Myosin light chain kinase (MLCK) gene disruption in Dictyostelium: a role for MLCK-A in cytokinesis and evidence for multiple MLCKs. Proceedings of the National Academy of Sciences of the United States of America. 93: 12321-6. PMID 8901579 DOI: 10.1073/pnas.93.22.12321  1
1996 Nuckolls GH, Osherov N, Loomis WF, Spudich JA. The Dictyostelium dual-specificity kinase splA is essential for spore differentiation. Development (Cambridge, England). 122: 3295-305. PMID 8898241  1
1996 Ruppel KM, Spudich JA. Structure-function studies of the myosin motor domain: importance of the 50-kDa cleft. Molecular Biology of the Cell. 7: 1123-36. PMID 8862525  1
1996 Simmons RM, Finer JT, Chu S, Spudich JA. Quantitative measurements of force and displacement using an optical trap. Biophysical Journal. 70: 1813-22. PMID 8785341 DOI: 10.1016/S0006-3495(96)79746-1  1
1996 Patterson B, Spudich JA. Cold-sensitive mutations of Dictyostelium myosin heavy chain highlight functional domains of the myosin motor. Genetics. 143: 801-10. PMID 8725228  1
1996 Coppin CM, Finer JT, Spudich JA, Vale RD. Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy. Proceedings of the National Academy of Sciences of the United States of America. 93: 1913-7. PMID 8700858  1
1996 Goodson HV, Anderson BL, Warrick HM, Pon LA, Spudich JA. Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton. The Journal of Cell Biology. 133: 1277-91. PMID 8682864 DOI: 10.1083/jcb.133.6.1277  1
1996 Howard J, Spudich JA. Is the lever arm of myosin a molecular elastic element? Proceedings of the National Academy of Sciences of the United States of America. 93: 4462-4. PMID 8633090  1
1996 Uyeda TQ, Abramson PD, Spudich JA. The neck region of the myosin motor domain acts as a lever arm to generate movement. Proceedings of the National Academy of Sciences of the United States of America. 93: 4459-64. PMID 8633089 DOI: 10.1073/pnas.93.9.4459  1
1996 Moores SL, Sabry JH, Spudich JA. Myosin dynamics in live Dictyostelium cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 443-6. PMID 8552657 DOI: 10.1073/pnas.93.1.443  1
1995 Spudich JA, Finer J, Simmons B, Ruppel K, Patterson B, Uyeda T. Myosin structure and function. Cold Spring Harbor Symposia On Quantitative Biology. 60: 783-91. PMID 8824453  1
1995 Finer JT, Mehta AD, Spudich JA. Characterization of single actin-myosin interactions. Biophysical Journal. 68: 291S-296S; discussio. PMID 7787094  1
1995 Coppin CM, Finer JT, Spudich JA, Vale RD. Measurement of the isometric force exerted by a single kinesin molecule. Biophysical Journal. 68: 242S-244S. PMID 7787084  1
1995 Ruppel KM, Spudich JA. Myosin motor function: structural and mutagenic approaches. Current Opinion in Cell Biology. 7: 89-93. PMID 7755994 DOI: 10.1016/0955-0674(95)80049-2  1
1995 Goodson HV, Spudich JA. Identification and molecular characterization of a yeast myosin I. Cell Motility and the Cytoskeleton. 30: 73-84. PMID 7728870 DOI: 10.1002/cm.970300109  1
1995 Ruppel KM, Lorenz M, Spudich JA. Myosin structure/function: a combined mutagenesis-crystallography approach. Current Opinion in Structural Biology. 5: 181-6. PMID 7648319 DOI: 10.1016/0959-440X(95)80073-5  1
1995 Patterson B, Spudich JA. A novel positive selection for identifying cold-sensitive myosin II mutants in Dictyostelium. Genetics. 140: 505-15. PMID 7498732  1
1994 Uyeda TQ, Ruppel KM, Spudich JA. Enzymatic activities correlate with chimaeric substitutions at the actin-binding face of myosin. Nature. 368: 567-9. PMID 8139694 DOI: 10.1038/368567a0  1
1994 Finer JT, Simmons RM, Spudich JA. Single myosin molecule mechanics: piconewton forces and nanometre steps. Nature. 368: 113-9. PMID 8139653 DOI: 10.1038/368113a0  1
1994 LeBlanc-Straceski JM, Fukui Y, Sohn RL, Spudich JA, Leinwand LA. Functional analysis of a cardiac myosin rod in Dictyostelium discoideum. Cell Motility and the Cytoskeleton. 27: 313-26. PMID 8069939 DOI: 10.1002/cm.970270404  1
1994 Ruppel KM, Uyeda TQ, Spudich JA. Role of highly conserved lysine 130 of myosin motor domain. In vivo and in vitro characterization of site specifically mutated myosin. The Journal of Biological Chemistry. 269: 18773-80. PMID 8034630  1
1994 Spudich JA. How molecular motors work. Nature. 372: 515-8. PMID 7990922 DOI: 10.1038/372515a0  1
1994 Springer ML, Patterson B, Spudich JA. Stage-specific requirement for myosin II during Dictyostelium development. Development (Cambridge, England). 120: 2651-60. PMID 7956839  1
1994 Lee RJ, Egelhoff TT, Spudich JA. Molecular genetic truncation analysis of filament assembly and phosphorylation domains of Dictyostelium myosin heavy chain. Journal of Cell Science. 107: 2875-86. PMID 7876354  1
1993 Goodson HV, Spudich JA. Molecular evolution of the myosin family: relationships derived from comparisons of amino acid sequences. Proceedings of the National Academy of Sciences of the United States of America. 90: 659-63. PMID 8421702 DOI: 10.1073/pnas.90.2.659  1
1993 Titus MA, Wessels D, Spudich JA, Soll D. The unconventional myosin encoded by the myoA gene plays a role in Dictyostelium motility. Molecular Biology of the Cell. 4: 233-46. PMID 8382977  1
1993 Schröder RR, Manstein DJ, Jahn W, Holden H, Rayment I, Holmes KC, Spudich JA. Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1. Nature. 364: 171-4. PMID 8321290 DOI: 10.1038/364171a0  1
1993 Uyeda TQ, Spudich JA. A functional recombinant myosin II lacking a regulatory light chain-binding site. Science (New York, N.Y.). 262: 1867-70. PMID 8266074  1
1993 Warrick HM, Simmons RM, Finer JT, Uyeda TQ, Chu S, Spudich JA. In vitro methods for measuring force and velocity of the actin-myosin interaction using purified proteins Methods in Cell Biology. 39: 1-21. PMID 8246790  1
1993 Simmons RM, Finer JT, Warrick HM, Kralik B, Chu S, Spudich JA, Yanagida T, Oiwa K, Lombardi V, Huxley. Force on single actin filaments in a motility assay measured with an optical trap Advances in Experimental Medicine and Biology. 332: 331-337. PMID 8109348  1
1993 Egelhoff TT, Lee RJ, Spudich JA. Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo Cell. 75: 363-371. PMID 7691416 DOI: 10.1016/0092-8674(93)80077-R  1
1992 Kron SJ, Drubin DG, Botstein D, Spudich JA. Yeast actin filaments display ATP-dependent sliding movement over surfaces coated with rabbit muscle myosin Proceedings of the National Academy of Sciences of the United States of America. 89: 4466-4470. PMID 1533933 DOI: 10.1073/pnas.89.10.4466  1
1992 Tan JL, Ravid S, Spudich JA. Control of nonmuscle myosins by phosphorylation Annual Review of Biochemistry. 61: 721-759. PMID 1497323  1
1992 Kubalek EW, Uyeda TQP, Spudich JA. A Dictyostelium myosin II lacking a proximal 58-kDa portion of the tail is functional in vitro and in vivo Molecular Biology of the Cell. 3: 1455-1462. PMID 1493338  1
1992 Ravid S, Spudich JA. Membrane-bound Dictyostelium myosin heavy chain kinase: A developmentally regulated substrate-specific member of the protein kinase C family Proceedings of the National Academy of Sciences of the United States of America. 89: 5877-5881. PMID 1321427 DOI: 10.1073/pnas.89.13.5877  1
1991 Egelhoff TT, Spudich JA. Molecular genetics of cell migration: Dictyostelium as a model system Trends in Genetics. 7: 161-166. PMID 2068788 DOI: 10.1016/0168-9525(91)90380-9  1
1991 Kron SJ, Toyoshima YY, Uyeda TQP, Spudich JA. Assays for actin sliding movement over myosin-coated surfaces Methods in Enzymology. 196: 399-416. PMID 2034132  1
1991 Egelhoff TT, Titus MA, Manstein DJ, Ruppel KM, Spudich JA. Molecular genetic tools for study of the cytoskeleton in Dictyostelium. Methods in Enzymology. 196: 319-34. PMID 2034127  1
1991 Egelhoff TT, Brown SS, Spudich JA. Spatial and temporal control of nonmuscle myosin localization: identification of a domain that is necessary for myosin filament disassembly in vivo. The Journal of Cell Biology. 112: 677-88. PMID 1899668  1
1991 Manstein DJ, Ruppel KM, Kubalek L, Spudich JA. Manipulation and expression of molecular motors in Dictyostelium discoideum Journal of Cell Science. 98: 63-65. PMID 1885661  1
1991 Kron SJ, Uyeda TQP, Warrick HM, Spudich JA. An approach to reconstituting motility of single myosin molecules Journal of Cell Science. 98: 129-133. PMID 1885651  1
1991 Uyeda TQP, Warrick HM, Kron SJ, Spudich JA. Quantized velocities at low myosin densities in an in vitro motility assay Nature. 352: 307-311. PMID 1852205  1
1991 Patterson B, Ruppel KM, Spudich JA. Molecular genetic approaches to the cytoskeleton in Dictyostelium Current Opinion in Genetics and Development. 1: 378-382. PMID 1840895 DOI: 10.1016/S0959-437X(05)80303-X  1
1991 Tan JL, Spudich JA. Characterization and bacterial expression of the dictyostelium myosin light chain kinase cDNA: Identification of an autoinhibitory domain Journal of Biological Chemistry. 266: 16044-16049. PMID 1651931  1
1991 Spudich JA, Warrick HM. A tale of two motors Current Opinion in Structural Biology. 1: 264-269. DOI: 10.1016/0959-440X(91)90072-2  1
1990 Egelhoff TT, Manstein DJ, Spudich JA. Complementation of myosin null mutants in Dictyostelium discoideum by direct functional selection Developmental Biology. 137: 359-367. PMID 2406175 DOI: 10.1016/0012-1606(90)90260-P  1
1990 Fukui Y, De Lozanne A, Spudich JA. Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant Journal of Cell Biology. 110: 367-378. PMID 2404992  1
1990 O'Halloran TJ, Ravid S, Spudich JA. Expression of Dictyostelium myosin tail segments in Escherichia coli: Domains required for assembly and phosphorylation Journal of Cell Biology. 110: 63-70. PMID 2404023  1
1990 Tan JL, Spudich JA. Dictyostelium myosin light chain kinase: Purification and characterization Journal of Biological Chemistry. 265: 13818-13824. PMID 2380188  1
1990 O'Halloran TJ, Spudich JA. Genetically engineered truncated myosin in Dictyostelium: The carboxyl-terminal regulatory domain is not required for the developmental cycle Proceedings of the National Academy of Sciences of the United States of America. 87: 8110-8114. PMID 2236024  1
1990 Titus MA, Warrick HM, Spudich JA. Molecular genetics: a key to the cytoskeleton's closet. Current Opinion in Cell Biology. 2: 116-20. PMID 2183835 DOI: 10.1016/S0955-0674(05)80041-9  1
1990 Spudich JA. Motor molecules in motion Nature. 348: 284-285. PMID 2147458  1
1990 Toyoshima YY, Kron SJ, Spudich JA. The myosin step size: Measurement of the unit displacement per ATP hydrolyzed in an in vitro assay Proceedings of the National Academy of Sciences of the United States of America. 87: 7130-7134. PMID 2144900  1
1990 Uyeda TQP, Kron SJ, Spudich JA. Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin Journal of Molecular Biology. 214: 699-710. PMID 2143785 DOI: 10.1016/0022-2836(90)90287-V  1
1990 Schwyter DH, Kron SJ, Toyoshima YY, Spudich JA, Reisler E. Subtilisin cleavage of actin inhibits in vitro sliding movement of actin filaments over myosin Journal of Cell Biology. 111: 465-470. PMID 2143196  1
1990 Ruppel KM, Egelhoff TT, Spudich JA. Purification of a functional recombinant myosin fragment from Dictyostelium discoideum Annals of the New York Academy of Sciences. 582: 147-155. PMID 2141452 DOI: 10.1111/j.1749-6632.1990.tb21675.x  1
1990 Tan JL, Spudich JA. Developmentally regulated protein-tyrosine kinase genes in Dictyostelium discoideum Molecular and Cellular Biology. 10: 3578-3583. PMID 1972546  1
1989 Pasternak C, Spudich JA, Elson EL. Capping of surface receptors and concomitant cortical tension are generated by conventional myosin Nature. 341: 549-551. PMID 2797182  1
1989 Pasternak C, Flicker PF, Ravid S, Spudich JA. Intermolecular versus intramolecular interactions of Dictyostelium myosin: possible regulation by heavy chain phosphorylation. The Journal of Cell Biology. 109: 203-10. PMID 2745547  1
1989 Manstein DJ, Titus MA, De Lozanne A, Spudich JA. Gene replacement in Dictyostelium: generation of myosin null mutants. The Embo Journal. 8: 923-32. PMID 2721503  1
1989 Toyoshima YY, Toyoshima C, Spudich JA. Bidirectional movement of actin filaments along tracks of myosin heads Nature. 341: 154-156. PMID 2674720  1
1989 Welker DL, De Lozanne A, Spudich JA. Linkage analysis of the myosin heavy chain gene in Dictyostelium discoideum using a mutation generated by homologous recombination Mgg Molecular & General Genetics. 216: 498-502. PMID 2568578 DOI: 10.1007/BF00334396  1
1989 Nachmias VT, Fukui Y, Spudich JA. Chemoattractant-elicited translocation of myosin in motile Dictyostelium Cell Motility and the Cytoskeleton. 13: 158-169. PMID 2550149  1
1989 Ravid S, Spudich JA. Myosin heavy chain kinase from developed Dictyostelium cells. Purification and characterization Journal of Biological Chemistry. 264: 15144-15150. PMID 2549052  1
1989 Egelhoff TT, Brown SS, Manstein DJ, Spudich JA. Hygromycin resistance as a selectable marker in Dictyostelium discoideum. Molecular and Cellular Biology. 9: 1965-8. PMID 2546056  1
1989 Manstein DJ, Ruppel KM, Spudich JA. Expression and characterization of a functional myosin head fragment in Dictyostelium discoideum Science. 246: 656-658. PMID 2530629  1
1989 Titus MA, Warrick HM, Spudich JA. Multiple actin-based motor genes in Dictyostelium. Cell Regulation. 1: 55-63. PMID 2519618  1
1989 Spudich JA. In pursuit of myosin function Cell Regulation. 1: 1-11. PMID 2519609  1
1988 Warrick HM, Spudich JA. Codon preference in Dictyostelium discoideum Nucleic Acids Research. 16: 6617-6635. PMID 3399410 DOI: 10.1093/nar/16.14.6617  1
1988 Curmi PM, Stone DB, Schneider DK, Spudich JA, Mendelson RA. Comparison of the structure of myosin subfragment 1 bound to actin and free in solution. A neutron scattering study using actin made "invisible" by deuteration. Journal of Molecular Biology. 203: 781-98. PMID 3062180 DOI: 10.1016/0022-2836(88)90209-4  1
1988 McNally EM, Goodwin EB, Spudich JA, Leinwand LA. Coexpression and assembly of myosin heavy chain and myosin light chain in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 85: 7270-7273. PMID 3050991  1
1987 Spudich JA. Chapter 1 Introductory Remarks and Some Biochemical Considerations Methods in Cell Biology. 28: 3-8. PMID 3600410 DOI: 10.1016/S0091-679X(08)61634-9  1
1987 De Lozanne A, Spudich JA. Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination Science. 236: 1086-1091. PMID 3576222  1
1987 Hynes TR, Block SM, White BT, Spudich JA. Movement of myosin fragments in vitro: domains involved in force production. Cell. 48: 953-63. PMID 3548997 DOI: 10.1016/0092-8674(87)90704-5  1
1987 De Lozanne A, Berlot CH, Leinwand LA, Spudich JA. Expression in Escherichia coli of a functional Dictyostelium myosin tail fragment Journal of Cell Biology. 105: 2999-3005. PMID 3320060  1
1987 Warrick HM, Spudich JA. Myosin structure and function in cell motility Annual Review of Cell Biology. 3: 379-421. PMID 3318880  1
1987 Toyoshima YY, Kron SJ, McNally EM, Niebling KR, Toyoshima C, Spudich JA. Myosin subfragment-1 is sufficient to move actin filaments in vitro Nature. 328: 536-539. PMID 2956522  1
1987 Spudich JA. Preface Methods in Cell Biology. 28: xv-xvi. DOI: 10.1016/S0091-679X(08)61632-5  1
1969 Bonsen PP, Spudich JA, Nelson DL, Kornberg A. Biochemical studies of bacterial sporulation and germination. XII. A sulfonic acid as a major sulfur compound of Bacillus subtilis spores. Journal of Bacteriology. 98: 62-8. PMID 4977690  0.96
1969 Spudich JA, Kornberg A. Biochemical studies of bacterial sporulation and germination. 13. Adenylate kinase of vegetative cells and spores of Bacillus subtilis. Journal of Bacteriology. 98: 69-74. PMID 4976471  0.96
1968 Spudich JA, Kornberg A. Biochemical studies of bacterial sporulation and germaination. VII. Protein turnover during sporulation of Bacillus subtilis. The Journal of Biological Chemistry. 243: 4600-5. PMID 4971699  0.96
1968 Spudich JA, Kornberg A. Biochemical studies of bacterial sporulation and germination. VI. Origin of spore core and coat proteins. The Journal of Biological Chemistry. 243: 4588-99. PMID 4971698  0.96
1968 Kornberg A, Spudich JA, Nelson DL, Deutscher MP. Origin of proteins in sporulation. Annual Review of Biochemistry. 37: 51-78. PMID 4875719 DOI: 10.1146/annurev.bi.37.070168.000411  0.68
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