Jeffrey A. Bluestone - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Cell Biology, Immunology, Molecular Biology

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bluestone JA, Tang Q. Solving the Puzzle of Immune Tolerance for β-Cell Replacement Therapy for Type 1 Diabetes. Cell Stem Cell. 27: 505-507. PMID 33007232 DOI: 10.1016/j.stem.2020.09.008  1
2020 Schumann K, Raju SS, Lauber M, Kolb S, Shifrut E, Cortez JT, Skartsis N, Nguyen VQ, Woo JM, Roth TL, Yu R, Nguyen MLT, Simeonov DR, Nguyen DN, Targ S, ... ... Bluestone JA, et al. Functional CRISPR dissection of gene networks controlling human regulatory T cell identity. Nature Immunology. PMID 32989329 DOI: 10.1038/s41590-020-0784-4  1
2020 Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, ... ... Bluestone JA, et al. CRISPR screen in regulatory T cells reveals modulators of Foxp3. Nature. PMID 32499641 DOI: 10.1038/s41586-020-2246-4  0.48
2020 Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scottà C, ... ... Bluestone JA, et al. Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials. Lancet (London, England). 395: 1627-1639. PMID 32446407 DOI: 10.1016/S0140-6736(20)30167-7  1
2020 Roth TL, Li PJ, Blaeschke F, Nies JF, Apathy R, Mowery C, Yu R, Nguyen MLT, Lee Y, Truong A, Hiatt J, Wu D, Nguyen DN, Goodman D, Bluestone JA, et al. Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies. Cell. PMID 32302591 DOI: 10.1016/j.cell.2020.03.039  0.48
2019 Nguyen DN, Roth TL, Li PJ, Chen PA, Apathy R, Mamedov MR, Vo LT, Tobin VR, Goodman D, Shifrut E, Bluestone JA, Puck JM, Szoka FC, Marson A. Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency. Nature Biotechnology. PMID 31819258 DOI: 10.1038/s41587-019-0325-6  0.48
2019 Ferreira LMR, Muller YD, Bluestone JA, Tang Q. Next-generation regulatory T cell therapy. Nature Reviews. Drug Discovery. PMID 31541224 DOI: 10.1038/s41573-019-0041-4  1
2019 Azimi CS, Tang Q, Roybal KT, Bluestone JA. NextGen cell-based immunotherapies in cancer and other immune disorders. Current Opinion in Immunology. 59: 79-87. PMID 31071513 DOI: 10.1016/j.coi.2019.03.007  1
2019 Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. PMID 30709738 DOI: 10.1016/j.immuni.2018.12.016  0.48
2018 Esensten JH, Muller YD, Bluestone JA, Tang Q. Regulatory T cell therapy for autoimmune and autoinflammatory diseases: the next frontier. The Journal of Allergy and Clinical Immunology. PMID 30367909 DOI: 10.1016/j.jaci.2018.10.015  1
2018 Bluestone JA, Tang Q. T cells-the next frontier of cell therapy. Science (New York, N.Y.). 362: 154-155. PMID 30309932 DOI: 10.1126/science.aau2688  1
2018 Dall'Era M, Pauli ML, Remedios K, Taravati K, Sandoval PM, Putnam AL, Lares A, Haemel A, Tang Q, Hellerstein M, Fitch M, McNamara J, Welch B, Bluestone JA, Wofsy D, et al. Adoptive Regulatory T Cell Therapy in a Patient with Systemic Lupus Erythematosus. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30277008 DOI: 10.1002/art.40737  1
2018 Abbas AK, Trotta E, R Simeonov D, Marson A, Bluestone JA. Revisiting IL-2: Biology and therapeutic prospects. Science Immunology. 3. PMID 29980618 DOI: 10.1126/sciimmunol.aat1482  0.48
2018 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Bluestone JA, et al. Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 29899441 DOI: 10.1038/s41586-018-0227-7  0.48
2018 Wang D, Quiros J, Mahuron K, Pai CC, Ranzani V, Young A, Silveria S, Harwin T, Abnousian A, Pagani M, Rosenblum MD, Van Gool F, Fong L, Bluestone JA, DuPage M. Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity. Cell Reports. 23: 3262-3274. PMID 29898397 DOI: 10.1016/j.celrep.2018.05.050  0.48
2018 Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Cell Stem Cell. 22: 810-823. PMID 29859172 DOI: 10.1016/j.stem.2018.05.016  1
2018 Spence A, Purtha W, Tam J, Dong S, Kim Y, Ju CH, Sterling T, Nakayama M, Robinson WH, Bluestone JA, Anderson MS, Tang Q. Revealing the specificity of regulatory T cells in murine autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29712852 DOI: 10.1073/pnas.1715590115  1
2017 Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, et al. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Frontiers in Immunology. 8: 1844. PMID 29379498 DOI: 10.3389/fimmu.2017.01844  1
2017 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Bluestone JA, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/nature23875  0.48
2017 Chandran S, Tang Q, Sarwal M, Laszik ZG, Putnam AL, Lee K, Leung J, Nguyen V, Sigdel T, Tavares EC, Yang JYC, Hellerstein M, Fitch M, Bluestone JA, Vincenti F. Polyclonal Regulatory T cell Therapy for Control of Inflammation in Kidney Transplants. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28675676 DOI: 10.1111/ajt.14415  1
2016 Esensten JH, Bluestone JA, Lim WA. Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials. Annual Review of Pathology. PMID 27959633 DOI: 10.1146/annurev-pathol-052016-100304  0.32
2016 Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA. CD28 Costimulation: From Mechanism to Therapy. Immunity. 44: 973-88. PMID 27192564 DOI: 10.1016/j.immuni.2016.04.020  0.64
2016 DuPage M, Bluestone JA. Harnessing the plasticity of CD4(+) T cells to treat immune-mediated disease. Nature Reviews. Immunology. 16: 149-63. PMID 26875830 DOI: 10.1038/nri.2015.18  0.48
2015 Bluestone JA, Buckner JH, Fitch M, Gitelman SE, Gupta S, Hellerstein MK, Herold KC, Lares A, Lee MR, Li K, Liu W, Long SA, Masiello LM, Nguyen V, Putnam AL, et al. Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Science Translational Medicine. 7: 315ra189. PMID 26606968 DOI: 10.1126/scitranslmed.aad4134  0.64
2015 Kishnani PS, Dickson PI, Muldowney L, Lee JJ, Rosenberg A, Abichandani R, Bluestone JA, Burton BK, Dewey M, Freitas A, Gavin D, Griebel D, Hogan M, Holland S, Tanpaiboon P, et al. Immune response to enzyme replacement therapies in lysosomal storage diseases and the role of immune tolerance induction. Molecular Genetics and Metabolism. PMID 26597321 DOI: 10.1016/j.ymgme.2015.11.001  0.64
2015 Spence A, Klementowicz JE, Bluestone JA, Tang Q. Targeting Treg signaling for the treatment of autoimmune diseases. Current Opinion in Immunology. 37: 11-20. PMID 26432763 DOI: 10.1016/j.coi.2015.09.002  0.64
2015 Schumann K, Lin S, Boyer E, Simeonov DR, Subramaniam M, Gate RE, Haliburton GE, Ye CJ, Bluestone JA, Doudna JA, Marson A. Generation of knock-in primary human T cells using Cas9 ribonucleoproteins. Proceedings of the National Academy of Sciences of the United States of America. 112: 10437-42. PMID 26216948 DOI: 10.1073/pnas.1512503112  0.48
2015 Molofsky AB, Van Gool F, Liang HE, Van Dyken SJ, Nussbaum JC, Lee J, Bluestone JA, Locksley RM. Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation. Immunity. 43: 161-74. PMID 26092469 DOI: 10.1016/j.immuni.2015.05.019  0.64
2015 Fuhrman CA, Yeh WI, Seay HR, Saikumar Lakshmi P, Chopra G, Zhang L, Perry DJ, McClymont SA, Yadav M, Lopez MC, Baker HV, Zhang Y, Li Y, Whitley M, von Schack D, ... ... Bluestone JA, et al. Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. Journal of Immunology (Baltimore, Md. : 1950). 195: 145-55. PMID 25994968 DOI: 10.4049/jimmunol.1402381  0.48
2015 Bluestone JA, Bour-Jordan H, Cheng M, Anderson M. T cells in the control of organ-specific autoimmunity. The Journal of Clinical Investigation. 125: 2250-60. PMID 25985270 DOI: 10.1172/JCI78089  0.4
2015 Bluestone JA, Tang Q. Immunotherapy: making the case for precision medicine. Science Translational Medicine. 7: 280ed3. PMID 25810308 DOI: 10.1126/scitranslmed.aaa9846  1
2015 DuPage M, Chopra G, Quiros J, Rosenthal WL, Morar MM, Holohan D, Zhang R, Turka L, Marson A, Bluestone JA. The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation. Immunity. 42: 227-38. PMID 25680271 DOI: 10.1016/j.immuni.2015.01.007  0.64
2015 Huynh A, DuPage M, Priyadharshini B, Sage PT, Quiros J, Borges CM, Townamchai N, Gerriets VA, Rathmell JC, Sharpe AH, Bluestone JA, Turka LA. Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability. Nature Immunology. 16: 188-96. PMID 25559257 DOI: 10.1038/ni.3077  0.48
2015 Szot GL, Yadav M, Lang J, Kroon E, Kerr J, Kadoya K, Brandon EP, Baetge EE, Bour-Jordan H, Bluestone JA. Tolerance induction and reversal of diabetes in mice transplanted with human embryonic stem cell-derived pancreatic endoderm. Cell Stem Cell. 16: 148-57. PMID 25533131 DOI: 10.1016/j.stem.2014.12.001  0.4
2015 Fuhrman CA, Yeh WI, Seay HR, Lakshmi PS, Chopra G, Zhang L, Perry DJ, McClymont SA, Yadav M, Lopez MC, Baker HV, Zhang Y, Li Y, Whitley M, Von Schack D, ... ... Bluestone JA, et al. Divergent phenotypes of human regulatory T cells expressing the receptors TIGIT and CD226 Journal of Immunology. 195: 145-155. DOI: 10.4049/jimmunol.1402381  0.48
2014 Xu P, Bailey-Bucktrout S, Xi Y, Xu D, Du D, Zhang Q, Xiang W, Liu J, Melton A, Sheppard D, Chapman HA, Bluestone JA, Derynck R. Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling. Molecular Cell. 56: 723-37. PMID 25526531 DOI: 10.1016/j.molcel.2014.11.027  0.64
2014 Van Gool F, Molofsky AB, Morar MM, Rosenzwajg M, Liang HE, Klatzmann D, Locksley RM, Bluestone JA. Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy. Blood. 124: 3572-6. PMID 25323825 DOI: 10.1182/blood-2014-07-587493  0.64
2014 Folias AE, Penaranda C, Su AL, Bluestone JA, Hebrok M. Aberrant innate immune activation following tissue injury impairs pancreatic regeneration. Plos One. 9: e102125. PMID 25010227 DOI: 10.1371/journal.pone.0102125  0.64
2014 Roep BO, Solvason N, Gottlieb PA, Abreu JR, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, Von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, et al. Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8 + T cells in type 1 diabetes Diabetes Technology and Therapeutics. 16: S88. DOI: 10.1089/dia.2014.1510  0.64
2014 Guleria I, Bupp MG, Dada S, Fife BT, Tang Q, Ansari MJ, Trikudanathan S, Vadivel N, Fiorina P, Yagita H, Azuma M, Atkinson M, Bluestone JA, Sayegh MH. Corrigendum to 'Mechanisms of PDL1-mediated regulation of autoimmune diabetes' [Clin. Immunol. 125 (2007) 16-25] Clinical Immunology. 150: 134. DOI: 10.1016/j.clim.2013.09.004  0.64
2013 Gitelman SE, Gottlieb PA, Rigby MR, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, Ding L, ... Bluestone JA, et al. Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. The Lancet. Diabetes & Endocrinology. 1: 306-16. PMID 24622416 DOI: 10.1016/S2213-8587(13)70065-2  0.64
2013 Bailey-Bucktrout SL, Martinez-Llordella M, Zhou X, Anthony B, Rosenthal W, Luche H, Fehling HJ, Bluestone JA. Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response. Immunity. 39: 949-62. PMID 24238343 DOI: 10.1016/j.immuni.2013.10.016  0.64
2013 Tang Q, Bluestone JA. Regulatory T-cell therapy in transplantation: moving to the clinic. Cold Spring Harbor Perspectives in Medicine. 3. PMID 24186492 DOI: 10.1101/cshperspect.a015552  1
2013 Putnam AL, Safinia N, Medvec A, Laszkowska M, Wray M, Mintz MA, Trotta E, Szot GL, Liu W, Lares A, Lee K, Laing A, Lechler RI, Riley JL, Bluestone JA, et al. Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 3010-20. PMID 24102808 DOI: 10.1111/ajt.12433  0.64
2013 Martínez-Llordella M, Esensten JH, Bailey-Bucktrout SL, Lipsky RH, Marini A, Chen J, Mughal M, Mattson MP, Taub DD, Bluestone JA. CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response. The Journal of Experimental Medicine. 210: 1603-19. PMID 23878307 DOI: 10.1084/jem.20122387  0.64
2013 Wieland Brown LC, Penaranda C, Kashyap PC, Williams BB, Clardy J, Kronenberg M, Sonnenburg JL, Comstock LE, Bluestone JA, Fischbach MA. Production of α-galactosylceramide by a prominent member of the human gut microbiota. Plos Biology. 11: e1001610. PMID 23874157 DOI: 10.1371/journal.pbio.1001610  0.64
2013 de Kouchkovsky D, Esensten JH, Rosenthal WL, Morar MM, Bluestone JA, Jeker LT. microRNA-17-92 regulates IL-10 production by regulatory T cells and control of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 191: 1594-605. PMID 23858035 DOI: 10.4049/jimmunol.1203567  0.64
2013 Bour-Jordan H, Thompson HL, Giampaolo JR, Davini D, Rosenthal W, Bluestone JA. Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background. Journal of Autoimmunity. 45: 58-67. PMID 23850635 DOI: 10.1016/j.jaut.2013.06.005  0.64
2013 Villalta SA, Lang J, Kubeck S, Kabre B, Szot GL, Calderon B, Wasserfall C, Atkinson MA, Brekken RA, Pullen N, Arch RH, Bluestone JA. Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes. 62: 2870-8. PMID 23835340 DOI: 10.2337/db12-1619  0.4
2013 Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W, Boyle KD, Keyes-Elstein L, Aggarwal S, Phippard D, Sayre PH, McNamara J, Bluestone JA. Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes. 62: 3766-74. PMID 23835333 DOI: 10.2337/db13-0345  0.64
2013 Baumjohann D, Kageyama R, Clingan JM, Morar MM, Patel S, de Kouchkovsky D, Bannard O, Bluestone JA, Matloubian M, Ansel KM, Jeker LT. The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression. Nature Immunology. 14: 840-8. PMID 23812098 DOI: 10.1038/ni.2642  0.64
2013 Fischbach MA, Bluestone JA, Lim WA. Cell-based therapeutics: the next pillar of medicine. Science Translational Medicine. 5: 179ps7. PMID 23552369 DOI: 10.1126/scitranslmed.3005568  0.64
2013 Huang C, Martin S, Pfleger C, Du J, Buckner JH, Bluestone JA, Riley JL, Ziegler SF. Cutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28. Journal of Immunology (Baltimore, Md. : 1950). 190: 4470-3. PMID 23543754 DOI: 10.4049/jimmunol.1203561  0.64
2013 Herold KC, Vignali DA, Cooke A, Bluestone JA. Type 1 diabetes: translating mechanistic observations into effective clinical outcomes. Nature Reviews. Immunology. 13: 243-56. PMID 23524461 DOI: 10.1038/nri3422  0.64
2013 Abbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF. Regulatory T cells: recommendations to simplify the nomenclature. Nature Immunology. 14: 307-8. PMID 23507634 DOI: 10.1038/ni.2554  0.64
2013 Lebastchi J, Deng S, Lebastchi AH, Beshar I, Gitelman S, Willi S, Gottlieb P, Akirav EM, Bluestone JA, Herold KC. Immune therapy and β-cell death in type 1 diabetes. Diabetes. 62: 1676-80. PMID 23423576 DOI: 10.2337/db12-1207  0.64
2013 Herold KC, Gitelman SE, Willi SM, Gottlieb PA, Waldron-Lynch F, Devine L, Sherr J, Rosenthal SM, Adi S, Jalaludin MY, Michels AW, Dziura J, Bluestone JA. Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial. Diabetologia. 56: 391-400. PMID 23086558 DOI: 10.1007/s00125-012-2753-4  0.64
2012 Bluestone JA, Bour-Jordan H. Current and future immunomodulation strategies to restore tolerance in autoimmune diseases. Cold Spring Harbor Perspectives in Biology. 4. PMID 23125012 DOI: 10.1101/cshperspect.a007542  0.4
2012 Tang Q, Leung J, Melli K, Lay K, Chuu EL, Liu W, Bluestone JA, Kang SM, Peddi VR, Vincenti F. Altered balance between effector T cells and FOXP3+ HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients. Transplant International : Official Journal of the European Society For Organ Transplantation. 25: 1257-67. PMID 22994802 DOI: 10.1111/j.1432-2277.2012.01565.x  1
2012 Yadav M, Louvet C, Davini D, Gardner JM, Martinez-Llordella M, Bailey-Bucktrout S, Anthony BA, Sverdrup FM, Head R, Kuster DJ, Ruminski P, Weiss D, Von Schack D, Bluestone JA. Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo. The Journal of Experimental Medicine. 209: 1713-22, S1-19. PMID 22966003 DOI: 10.1084/jem.20120822  0.64
2012 Kim K, An HJ, Jun SH, Kim TJ, Lim SA, Park G, Na HB, Park YI, Hyeon T, Yee C, Bluestone JA, Kim J, Lee KM. Single step isolation and activation of primary CD3 + T lymphocytes using alcohol-dispersed electrospun magnetic nanofibers Nano Letters. 12: 4018-4024. PMID 22784189 DOI: 10.1021/nl301388d  0.64
2012 Penaranda C, Kuswanto W, Hofmann J, Kenefeck R, Narendran P, Walker LS, Bluestone JA, Abbas AK, Dooms H. IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 12668-73. PMID 22733744 DOI: 10.1073/pnas.1203692109  0.64
2012 Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, ... Bluestone JA, et al. Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function. Diabetes. 61: 2340-8. PMID 22721971 DOI: 10.2337/db12-0049  0.64
2012 Jeker LT, Zhou X, Gershberg K, de Kouchkovsky D, Morar MM, Stadthagen G, Lund AH, Bluestone JA. MicroRNA 10a marks regulatory T cells. Plos One. 7: e36684. PMID 22629323 DOI: 10.1371/journal.pone.0036684  0.64
2012 Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y, Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, ... ... Bluestone JA, et al. A resource for the conditional ablation of microRNAs in the mouse. Cell Reports. 1: 385-91. PMID 22570807 DOI: 10.1016/j.celrep.2012.02.008  0.64
2012 Beilke JN, Meagher CT, Hosiawa K, Champsaur M, Bluestone JA, Lanier LL. NK cells are not required for spontaneous autoimmune diabetes in NOD mice. Plos One. 7: e36011. PMID 22558306 DOI: 10.1371/journal.pone.0036011  0.64
2012 Jeker LT, Bour-Jordan H, Bluestone JA. Breakdown in peripheral tolerance in type 1 diabetes in mice and humans. Cold Spring Harbor Perspectives in Medicine. 2: a007807. PMID 22393537 DOI: 10.1101/cshperspect.a007807  0.4
2012 Tang Q, Bluestone JA, Kang SM. CD4(+)Foxp3(+) regulatory T cell therapy in transplantation. Journal of Molecular Cell Biology. 4: 11-21. PMID 22170955 DOI: 10.1093/jmcb/mjr047  1
2012 Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop? The notion of homicide or β-cell suicide revisited (Diabetes (2011) 60, (1370-1379)) Diabetes. 61: 1648. DOI: 10.2337/db12-er06a  0.64
2011 Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA. Pillars article: CTLA-4 can function as a negative regulator of T cell activation. Immunity. 1994. 1: 405-413. Journal of Immunology (Baltimore, Md. : 1950). 187: 3466-74. PMID 21934098  0.64
2011 Beyer M, Thabet Y, Müller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld EA, Böttcher J, Golovina T, Mayer CT, Hofmann A, ... ... Bluestone JA, et al. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nature Immunology. 12: 898-907. PMID 21841785 DOI: 10.1038/ni.2084  0.64
2011 Herold KC, Bluestone JA. Type 1 diabetes immunotherapy: is the glass half empty or half full? Science Translational Medicine. 3: 95fs1. PMID 21832236 DOI: 10.1126/scitranslmed.3002981  0.64
2011 Esplugues E, Huber S, Gagliani N, Hauser AE, Town T, Wan YY, O'Connor W, Rongvaux A, Van Rooijen N, Haberman AM, Iwakura Y, Kuchroo VK, Kolls JK, Bluestone JA, Herold KC, et al. Control of TH17 cells occurs in the small intestine. Nature. 475: 514-8. PMID 21765430 DOI: 10.1038/nature10228  0.64
2011 Penaranda C, Tang Q, Bluestone JA. Anti-CD3 therapy promotes tolerance by selectively depleting pathogenic cells while preserving regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 2015-22. PMID 21742976 DOI: 10.4049/jimmunol.1100713  1
2011 Rainbow DB, Moule C, Fraser HI, Clark J, Howlett SK, Burren O, Christensen M, Moody V, Steward CA, Mohammed JP, Fusakio ME, Masteller EL, Finger EB, Houchins JP, Naf D, ... ... Bluestone JA, et al. Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 187: 325-36. PMID 21613616 DOI: 10.4049/jimmunol.1003523  0.64
2011 Brennan TV, Tang Q, Liu FC, Hoang V, Bi M, Bluestone JA, Kang SM. Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts. The Journal of Surgical Research. 169: e69-75. PMID 21571317 DOI: 10.1016/j.jss.2011.03.021  1
2011 Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited. Diabetes. 60: 1370-9. PMID 21525508 DOI: 10.2337/db10-1797  0.64
2011 Bour-Jordan H, Esensten JH, Martinez-Llordella M, Penaranda C, Stumpf M, Bluestone JA. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family. Immunological Reviews. 241: 180-205. PMID 21488898 DOI: 10.1111/j.1600-065X.2011.01011.x  0.64
2011 McClymont SA, Putnam AL, Lee MR, Esensten JH, Liu W, Hulme MA, Hoffmüller U, Baron U, Olek S, Bluestone JA, Brusko TM. Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 186: 3918-26. PMID 21368230 DOI: 10.4049/jimmunol.1003099  0.64
2010 Melton AC, Bailey-Bucktrout SL, Travis MA, Fife BT, Bluestone JA, Sheppard D. Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. The Journal of Clinical Investigation. 120: 4436-44. PMID 21099117 DOI: 10.1172/JCI43786  0.64
2010 Posselt AM, Szot GL, Frassetto LA, Masharani U, Tavakol M, Amin R, McElroy J, Ramos MD, Kerlan RK, Fong L, Vincenti F, Bluestone JA, Stock PG. Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade. Transplantation. 90: 1595-601. PMID 20978464 DOI: 10.1097/TP.0b013e3181fe1377  0.4
2010 Brusko TM, Koya RC, Zhu S, Lee MR, Putnam AL, McClymont SA, Nishimura MI, Han S, Chang LJ, Atkinson MA, Ribas A, Bluestone JA. Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. Plos One. 5: e11726. PMID 20668510 DOI: 10.1371/journal.pone.0011726  0.64
2010 Bluestone JA, Herold K, Eisenbarth G. Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature. 464: 1293-300. PMID 20432533 DOI: 10.1038/nature08933  0.64
2010 Penaranda C, Tang Q, Ruddle NH, Bluestone JA. Prevention of diabetes by FTY720-mediated stabilization of peri-islet tertiary lymphoid organs. Diabetes. 59: 1461-8. PMID 20299465 DOI: 10.2337/db09-1129  0.64
2009 Penaranda C, Bluestone JA. Is antigen specificity of autoreactive T cells the key to islet entry? Immunity. 31: 534-6. PMID 19833083 DOI: 10.1016/j.immuni.2009.09.006  0.56
2009 Esensten JH, Wofsy D, Bluestone JA. Regulatory T cells as therapeutic targets in rheumatoid arthritis. Nature Reviews. Rheumatology. 5: 560-5. PMID 19798031 DOI: 10.1038/nrrheum.2009.183  0.64
2009 Fife BT, Pauken KE, Eagar TN, Obu T, Wu J, Tang Q, Azuma M, Krummel MF, Bluestone JA. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nature Immunology. 10: 1185-92. PMID 19783989 DOI: 10.1038/ni.1790  0.64
2009 Zhou X, Bailey-Bucktrout SL, Jeker LT, Penaranda C, Martínez-Llordella M, Ashby M, Nakayama M, Rosenthal W, Bluestone JA. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nature Immunology. 10: 1000-7. PMID 19633673 DOI: 10.1038/ni.1774  0.56
2009 Norquay LD, D'Aquino KE, Opare-Addo LM, Kuznetsova A, Haas M, Bluestone JA, White MF. Insulin receptor substrate-2 in beta-cells decreases diabetes in nonobese diabetic mice. Endocrinology. 150: 4531-40. PMID 19574401 DOI: 10.1210/en.2009-0395  0.64
2009 Esensten JH, Lee MR, Glimcher LH, Bluestone JA. T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function. Journal of Immunology (Baltimore, Md. : 1950). 183: 75-82. PMID 19535634 DOI: 10.4049/jimmunol.0804154  0.64
2009 Herold KC, Gitelman S, Greenbaum C, Puck J, Hagopian W, Gottlieb P, Sayre P, Bianchine P, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA. Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years. Clinical Immunology (Orlando, Fla.). 132: 166-73. PMID 19443276 DOI: 10.1016/j.clim.2009.04.007  0.64
2009 Bour-Jordan H, Bluestone JA. Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells. Immunological Reviews. 229: 41-66. PMID 19426214 DOI: 10.1111/j.1600-065X.2009.00775.x  0.4
2009 Louvet C, Kabre BG, Davini DW, Martinier N, Su MA, DeVoss JJ, Rosenthal WL, Anderson MS, Bour-Jordan H, Bluestone JA. A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy. The Journal of Experimental Medicine. 206: 507-14. PMID 19221395 DOI: 10.1084/jem.20082113  0.64
2009 Putnam AL, Brusko TM, Lee MR, Liu W, Szot GL, Ghosh T, Atkinson MA, Bluestone JA. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes. 58: 652-62. PMID 19074986 DOI: 10.2337/db08-1168  0.64
2008 Bluestone JA, Liu W, Yabu JM, Laszik ZG, Putnam A, Belingheri M, Gross DM, Townsend RM, Vincenti F. The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation American Journal of Transplantation. 8: 2086-2096. PMID 18828769 DOI: 10.1111/j.1600-6143.2008.02377.x  0.64
2008 Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, Stonebraker AC, Hu C, Wong FS, Szot GL, Bluestone JA, Gordon JI, Chervonsky AV. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature. 455: 1109-13. PMID 18806780 DOI: 10.1038/nature07336  0.64
2008 Zhou X, Jeker LT, Fife BT, Zhu S, Anderson MS, McManus MT, Bluestone JA. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. The Journal of Experimental Medicine. 205: 1983-91. PMID 18725525 DOI: 10.1084/jem.20080707  0.64
2008 Bluestone JA, Tang Q, Sedwick CE. T regulatory cells in autoimmune diabetes: past challenges, future prospects. Journal of Clinical Immunology. 28: 677-84. PMID 18716861 DOI: 10.1007/s10875-008-9242-z  0.64
2008 Fiorina P, Vergani A, Dada S, Jurewicz M, Wong M, Law K, Wu E, Tian Z, Abdi R, Guleria I, Rodig S, Dunussi-Joannopoulos K, Bluestone J, Sayegh MH. Targeting CD22 reprograms B-cells and reverses autoimmune diabetes. Diabetes. 57: 3013-24. PMID 18689692 DOI: 10.2337/db08-0420  0.4
2008 Cano DA, Rulifson IC, Heiser PW, Swigart LB, Pelengaris S, German M, Evan GI, Bluestone JA, Hebrok M. Regulated beta-cell regeneration in the adult mouse pancreas. Diabetes. 57: 958-66. PMID 18083786 DOI: 10.2337/db07-0913  0.64
2007 Travis MA, Reizis B, Melton AC, Masteller E, Tang Q, Proctor JM, Wang Y, Bernstein X, Huang X, Reichardt LF, Bluestone JA, Sheppard D. Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice. Nature. 449: 361-5. PMID 17694047 DOI: 10.1038/nature06110  0.64
2007 Sherry NA, Chen W, Kushner JA, Glandt M, Tang Q, Tsai S, Santamaria P, Bluestone JA, Brillantes AM, Herold KC. Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of beta-cells. Endocrinology. 148: 5136-44. PMID 17673522 DOI: 10.1210/en.2007-0358  0.64
2006 Fife BT, Guleria I, Gubbels Bupp M, Eagar TN, Tang Q, Bour-Jordan H, Yagita H, Azuma M, Sayegh MH, Bluestone JA. Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. The Journal of Experimental Medicine. 203: 2737-47. PMID 17116737 DOI: 10.1084/jem.20061577  0.64
2006 Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, ... ... Bluestone J, et al. International trial of the Edmonton protocol for islet transplantation. The New England Journal of Medicine. 355: 1318-30. PMID 17005949 DOI: 10.1056/NEJMoa061267  0.64
2006 Seyfert-Margolis V, Gisler TD, Asare AL, Wang RS, Dosch HM, Brooks-Worrell B, Eisenbarth GS, Palmer JP, Greenbaum CJ, Gitelman SE, Nepom GT, Bluestone JA, Herold KC. Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: Results of a blinded controlled study Diabetes. 55: 2588-2594. PMID 16936208 DOI: 10.2337/db05-1378  0.64
2006 Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. The Journal of Experimental Medicine. 203: 1701-11. PMID 16818678 DOI: 10.1084/jem.20060772  0.64
2006 Gross DM, Earle KE, Bluestone JA, Tang Q. Regulatory T cells and their role in type 1 diabetes Current Opinion in Endocrinology and Diabetes. 13: 319-324. DOI: 10.1097/01.med.0000235320.23917.c5  0.64
2005 Bluestone JA, Tang Q. How do CD4+CD25+ regulatory T cells control autoimmunity? Current Opinion in Immunology. 17: 638-42. PMID 16209918 DOI: 10.1016/j.coi.2005.09.002  1
2005 Bisikirska B, Colgan J, Luban J, Bluestone JA, Herold KC. TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs. The Journal of Clinical Investigation. 115: 2904-13. PMID 16167085 DOI: 10.1172/JCI23961  0.64
2005 Shoda LK, Young DL, Ramanujan S, Whiting CC, Atkinson MA, Bluestone JA, Eisenbarth GS, Mathis D, Rossini AA, Campbell SE, Kahn R, Kreuwel HT. A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity. 23: 115-26. PMID 16111631 DOI: 10.1016/j.immuni.2005.08.002  0.64
2005 Loser K, Scherer A, Krummen MBW, Varga G, Higuchi T, Schwarz T, Sharpe AH, Grabbe S, Bluestone JA, Beissert S. An important role of CD80/CD86-CTLA-4 signaling during photocarcinogenesis in mice Journal of Immunology. 174: 5298-5305. PMID 15843526 DOI: 10.4049/JIMMUNOL.174.9.5298  0.64
2005 Sperling AI, Bluestone JA. Non-classical MHC molecules: the first line of defence? Current Biology : Cb. 3: 294-6. PMID 15335753 DOI: 10.1016/0960-9822(93)90183-O  0.48
2004 Tang Q, Boden EK, Henriksen KJ, Bour-Jordan H, Bi M, Bluestone JA. Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function. European Journal of Immunology. 34: 2996-3005. PMID 15468055 DOI: 10.1002/eji.200425143  1
2004 Bluestone JA, Tang Q. Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 14622-6. PMID 15322272 DOI: 10.1073/pnas.0405234101  1
2004 Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J, Masteller EL, McDevitt H, Bonyhadi M, Bluestone JA. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. The Journal of Experimental Medicine. 199: 1455-65. PMID 15184499 DOI: 10.1084/jem.20040139  1
2003 Tang Q, Smith JA, Szot GL, Zhou P, Alegre ML, Henriksen KJ, Thompson CB, Bluestone JA. CD28/B7 regulation of anti-CD3-mediated immunosuppression in vivo. Journal of Immunology (Baltimore, Md. : 1950). 170: 1510-6. PMID 12538715  1
2002 Utset TO, Auger JA, Peace D, Zivin RA, Xu D, Jolliffe L, Alegre ML, Bluestone JA, Clark MR. Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial. The Journal of Rheumatology. 29: 1907-13. PMID 12233885  0.4
2002 Rulifson IC, Szot GL, Palmer E, Bluestone JA. Inability to induce tolerance through direct antigen presentation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2: 510-9. PMID 12118894  0.48
2002 Hwang KW, Sweatt WB, Brown IE, Blank C, Gajewski TF, Bluestone JA, Alegre ML. Cutting edge: Targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells Journal of Immunology. 169: 633-637. PMID 12097362  0.64
2002 Herold KC, Hagopian W, Auger JA, Poumian-Ruiz E, Taylor L, Donaldson D, Gitelman SE, Harlan DM, Xu D, Zivin RA, Bluestone JA. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. The New England Journal of Medicine. 346: 1692-8. PMID 12037148 DOI: 10.1056/NEJMoa012864  0.32
2001 Salomon B, Rhee L, Bour-Jordan H, Hsin H, Montag A, Soliven B, Arcella J, Girvin AM, Padilla J, Miller SD, Bluestone JA. Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice. The Journal of Experimental Medicine. 194: 677-84. PMID 11535635 DOI: 10.1084/jem.194.5.677  0.64
2001 Sperling AI, Bluestone JA. ICOS costimulation: It's not just for TH2 cells anymore. Nature Immunology. 2: 573-4. PMID 11429535 DOI: 10.1038/89709  0.36
2001 Wu Q, Salomon B, Chen M, Wang Y, Hoffman LM, Bluestone JA, Fu YX. Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor Journal of Experimental Medicine. 193: 1327-1332. PMID 11390440 DOI: 10.1084/jem.193.11.1327  0.64
2001 Alegre M, Fallarino F, Zhou P, Frauwirth K, Thistlethwaite J, Newell K, Gajewski T, Bluestone J. Transplantation and the CD28/CTLA4/B7 pathway Transplantation Proceedings. 33: 209-211. PMID 11266782 DOI: 10.1016/S0041-1345(00)01977-1  0.64
2000 Neville KL, Dal Canto MC, Bluestone JA, Miller SD. CD28 costimulatory blockade exacerbates disease severity and accelerates epitope spreading in a virus-induced autoimmune disease. Journal of Virology. 74: 8349-57. PMID 10954534 DOI: 10.1128/JVI.74.18.8349-8357.2000  0.64
1999 Rajagopal K, Sommers CL, Decker DC, Mitchell EO, Korthauer U, Sperling AI, Kozak CA, Love PE, Bluestone JA. RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation. The Journal of Experimental Medicine. 190: 1657-68. PMID 10587356  0.48
1997 Smith JA, Tso JY, Clark MR, Cole MS, Bluestone JA. Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy. The Journal of Experimental Medicine. 185: 1413-22. PMID 9126922 DOI: 10.1084/jem.185.8.1413  0.64
1997 Rulifson IC, Sperling AI, Fields PE, Fitch FW, Bluestone JA. CD28 costimulation promotes the production of Th2 cytokines. Journal of Immunology (Baltimore, Md. : 1950). 158: 658-65. PMID 8992981  0.64
1996 Sperling AI, Auger JA, Ehst BD, Rulifson IC, Thompson CB, Bluestone JA. CD28/B7 Interactions Deliver a Unique Signal to Naive T Cells That Regulates Cell Survival but Not Early Proliferation Journal of Immunology. 157: 3909-3917. PMID 8892622  0.64
1996 Bluestone JA, Khattri R, Sciammas R, Sperling AI. TCR gamma delta cells: a specialized T-cell subset in the immune system. Annual Review of Cell and Developmental Biology. 11: 307-53. PMID 8689560 DOI: 10.1146/annurev.cb.11.110195.001515  0.44
1996 La Motte RN, Rubin MA, Barr E, Leiden JM, Bluestone JA, Mokyr MB. Therapeutic effectiveness of the immunity elicited by P815 tumor cells engineered to express the B7-2 costimulatory molecule. Cancer Immunology, Immunotherapy : Cii. 42: 161-9. PMID 8640844 DOI: 10.1007/s002620050266  0.64
1995 Alegre ML, Lenschow DJ, Bluestone JA. Immunomodulation of transplant rejection using monoclonal antibodies and soluble receptors Digestive Diseases and Sciences. 40: 58-64. PMID 7821120 DOI: 10.1007/BF02063942  0.64
1993 Dent AL, Matis LA, Bluestone JA, Hedrick SM. Evidence for programmed cell death of self-reactive γδ T cell receptor-positive thymocytes European Journal of Immunology. 23: 2482-2487. PMID 8405049 DOI: 10.1002/eji.1830231016  0.64
1993 Sydora BC, Mixter PF, Houlden B, Hershberg R, Levy R, Comay M, Bluestone J, Kronenberg M. T-Cell Receptor γδ Diversity and Specificity of Intestinal Intraepithelial Lymphocytes: Analysis of IEL-Derived Hybridomas Cellular Immunology. 152: 305-322. PMID 8258140 DOI: 10.1006/cimm.1993.1293  0.64
1990 Lefrancois L, LeCorre R, Mayo J, Bluestone JA, Goodman T. Extrathymic selection of TCR γδ+ T cells by class II major histocompatibility complex molecules Cell. 63: 333-340. PMID 2208290 DOI: 10.1016/0092-8674(90)90166-C  0.64
1989 Houlden BA, Matis LA, Cron RQ, Widacki SM, Brown GD, Pampeno C, Meruelo D, Bluestone JA. A TCRγδ cell recognizing a novel TL-encoded gene product Cold Spring Harbor Symposia On Quantitative Biology. 54: 45-55. PMID 2576978  0.64
1988 Langlet C, Guimezanes A, Kaldy P, Boyer C, Buferne M, Poenie M, Tsien R, Leo O, Bluestone J, Leserman L. Role of Ti/CD3, Thy-1, and Ly-6 in cytolytic T-cell activation analyzed with Ti loss variants. Annals of the New York Academy of Sciences. 532: 33-43. PMID 2902820 DOI: 10.1111/j.1749-6632.1988.tb36323.x  0.64
1987 Bluestone JA, Pardoll D, Sharrow SO, Fowlkes BJ. Characterization of murine thymocytes with CDS-associated T-cell receptor structures Nature. 326: 82-84. PMID 3102972 DOI: 10.1038/326082a0  0.64
1987 Pardoll DM, Fowlkes BJ, Bluestone JA, Kruisbeek A, Maloy WL, Coligan JE, Schwartz RH. Differential expression of two distinct T-cell receptors during thymocyte development Nature. 326: 79-81. PMID 3102971 DOI: 10.1038/326079a0  0.64
1981 Bluestone JA, Sharrow SO, Epstein SL, Ozato K, Sachs DH. Induction of anti-H-2 antibodies without alloantigen exposure by in vivo administration of anti-idiotype Nature. 291: 233-235. PMID 6785654 DOI: 10.1038/291233a0  0.64
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