Michele Pagano - Publications

Affiliations: 
New York University, New York, NY, United States 
Area:
Oncology, Cell Biology, Molecular Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Mavrommati I, Faedda R, Galasso G, Li J, Burdova K, Fischer R, Kessler BM, Carrero ZI, Guardavaccaro D, Pagano M, D'Angiolella V. β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression. Cell Reports. 24: 3404-3412. PMID 30257202 DOI: 10.1016/j.celrep.2018.08.076  0.48
2018 Rona G, Roberti D, Yin Y, Pagan JK, Homer H, Sassani E, Zeke A, Busino L, Rothenberg E, Pagano M. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. Elife. 7. PMID 29985131 DOI: 10.7554/eLife.38771  0.56
2016 Dankert JF, Rona G, Clijsters L, Geter P, Skaar JR, Bermudez-Hernandez K, Sassani E, Fenyö D, Ueberheide B, Schneider R, Pagano M. Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2. Molecular Cell. PMID 27773672 DOI: 10.1016/j.molcel.2016.09.010  0.56
2015 Young LM, Marzio A, Perez-Duran P, Reid DA, Meredith DN, Roberti D, Star A, Rothenberg E, Ueberheide B, Pagano M. TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response. Cell Reports. 13: 451-9. PMID 26456830 DOI: 10.1016/j.celrep.2015.09.017  1
2015 Duan S, Pagano M. SPOP Mutations or ERG Rearrangements Result in Enhanced Levels of ERG to Promote Cell Invasion in Prostate Cancer. Molecular Cell. 59: 883-4. PMID 26384661 DOI: 10.1016/j.molcel.2015.09.003  1
2015 Skaar JR, Ferris AL, Wu X, Saraf A, Khanna KK, Florens L, Washburn MP, Hughes SH, Pagano M. The Integrator complex controls the termination of transcription at diverse classes of gene targets. Cell Research. 25: 288-305. PMID 25675981 DOI: 10.1038/cr.2015.19  1
2014 Skaar JR, Pagan JK, Pagano M. SCF ubiquitin ligase-targeted therapies. Nature Reviews. Drug Discovery. 13: 889-903. PMID 25394868 DOI: 10.1038/nrd4432  1
2014 Choi BH, Pagano M, Huang C, Dai W. Cdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin. The Journal of Biological Chemistry. 289: 17951-9. PMID 24811168 DOI: 10.1074/jbc.M114.559005  1
2014 Choi BH, Pagano M, Dai W. Plk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cycle. The Journal of Biological Chemistry. 289: 14066-74. PMID 24706748 DOI: 10.1074/jbc.M114.558155  1
2014 Horn M, Geisen C, Cermak L, Becker B, Nakamura S, Klein C, Pagano M, Antebi A. DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation. Developmental Cell. 28: 697-710. PMID 24613396 DOI: 10.1016/j.devcel.2014.01.028  1
2014 Kanarek N, Grivennikov SI, Leshets M, Lasry A, Alkalay I, Horwitz E, Shaul YD, Stachler M, Voronov E, Apte RN, Pagano M, Pikarsky E, Karin M, Ghosh S, Ben-Neriah Y. Critical role for IL-1β in DNA damage-induced mucositis. Proceedings of the National Academy of Sciences of the United States of America. 111: E702-11. PMID 24469832 DOI: 10.1073/pnas.1322691111  1
2013 Tsunematsu T, Takihara Y, Ishimaru N, Pagano M, Takata T, Kudo Y. Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis. Nature Communications. 4: 1885. PMID 23695679 DOI: 10.1038/ncomms2859  1
2013 Skaar JR, Pagan JK, Pagano M. Mechanisms and function of substrate recruitment by F-box proteins. Nature Reviews. Molecular Cell Biology. 14: 369-81. PMID 23657496 DOI: 10.1038/nrm3582  1
2013 Pagan J, Seto T, Pagano M, Cittadini A. Role of the ubiquitin proteasome system in the heart. Circulation Research. 112: 1046-58. PMID 23538275 DOI: 10.1161/CIRCRESAHA.112.300521  1
2013 Xing W, Busino L, Hinds TR, Marionni ST, Saifee NH, Bush MF, Pagano M, Zheng N. SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature. 496: 64-8. PMID 23503662 DOI: 10.1038/nature11964  0.56
2013 Li J, D'Angiolella V, Seeley ES, Kim S, Kobayashi T, Fu W, Campos EI, Pagano M, Dynlacht BD. USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110. Nature. 495: 255-9. PMID 23486064 DOI: 10.1038/nature11941  1
2013 Jeong YT, Cermak L, Guijarro MV, Hernando E, Pagano M. FBH1 protects melanocytes from transformation and is deregulated in melanomas. Cell Cycle (Georgetown, Tex.). 12: 1128-32. PMID 23466708 DOI: 10.4161/cc.24165  1
2013 Jeong YT, Rossi M, Cermak L, Saraf A, Florens L, Washburn MP, Sung P, Schildkraut CL, Schildkraut C, Pagano M. FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. The Journal of Cell Biology. 200: 141-9. PMID 23319600 DOI: 10.1083/jcb.201209002  1
2013 Fernández-Sáiz V, Targosz BS, Lemeer S, Eichner R, Langer C, Bullinger L, Reiter C, Slotta-Huspenina J, Schroeder S, Knorn AM, Kurutz J, Peschel C, Pagano M, Kuster B, Bassermann F. SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma. Nature Cell Biology. 15: 72-81. PMID 23263282 DOI: 10.1038/ncb2651  1
2013 D'Angiolella V, Esencay M, Pagano M. A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis. Trends in Cell Biology. 23: 135-40. PMID 23182110 DOI: 10.1016/j.tcb.2012.10.011  1
2012 Wu L, Grigoryan AV, Li Y, Hao B, Pagano M, Cardozo TJ. Specific small molecule inhibitors of Skp2-mediated p27 degradation. Chemistry & Biology. 19: 1515-24. PMID 23261596 DOI: 10.1016/j.chembiol.2012.09.015  1
2012 Busino L, Millman SE, Pagano M. SCF-mediated degradation of p100 (NF-κB2): mechanisms and relevance in multiple myeloma. Science Signaling. 5: pt14. PMID 23211527 DOI: 10.1126/scisignal.2003408  1
2012 Kim DS, Zhang W, Millman SE, Hwang BJ, Kwon SJ, Clayberger C, Pagano M, Krensky AM. Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes. Blood. 120: 1658-67. PMID 22797700 DOI: 10.1182/blood-2012-03-415968  1
2012 Kruiswijk F, Yuniati L, Magliozzi R, Low TY, Lim R, Bolder R, Mohammed S, Proud CG, Heck AJ, Pagano M, Guardavaccaro D. Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress. Science Signaling. 5: ra40. PMID 22669845 DOI: 10.1126/scisignal.2002718  0.48
2012 Ping Z, Lim R, Bashir T, Pagano M, Guardavaccaro D. APC/C (Cdh1) controls the proteasome-mediated degradation of E2F3 during cell cycle exit. Cell Cycle (Georgetown, Tex.). 11: 1999-2005. PMID 22580460 DOI: 10.4161/cc.20402  0.48
2012 Busino L, Millman SE, Scotto L, Kyratsous CA, Basrur V, O'Connor O, Hoffmann A, Elenitoba-Johnson KS, Pagano M. Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma. Nature Cell Biology. 14: 375-85. PMID 22388891 DOI: 10.1038/ncb2463  1
2012 Yang F, Hu L, Chen C, Yu J, O'Connell CB, Khodjakov A, Pagano M, Dai W. BubR1 is modified by sumoylation during mitotic progression. The Journal of Biological Chemistry. 287: 4875-82. PMID 22167194 DOI: 10.1074/jbc.M111.318261  1
2012 Duan S, Cermak L, Pagan JK, Rossi M, Martinengo C, di Celle PF, Chapuy B, Shipp M, Chiarle R, Pagano M. FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature. 481: 90-3. PMID 22113614 DOI: 10.1038/nature10688  1
2012 Silverman JS, Skaar JR, Pagano M. SCF ubiquitin ligases in the maintenance of genome stability. Trends in Biochemical Sciences. 37: 66-73. PMID 22099186 DOI: 10.1016/j.tibs.2011.10.004  1
2011 Mirchandani D, Roses DF, Inghirami G, Zeleniuch-Jacquotte A, Cangiarella J, Guth A, Safyan RA, Formenti SC, Pagano M, Muggia F. Loss of p27KIP1 expression in fully-staged node-negative breast cancer: association with lack of hormone receptors in T1a/b, but not T1c infiltrative ductal carcinoma. Anticancer Research. 31: 4401-5. PMID 22199306  1
2011 Duan S, Pagano M. Linking metabolism and cell cycle progression via the APC/C Cdh1 and SCF βTrCP ubiquitin ligases Proceedings of the National Academy of Sciences of the United States of America. 108: 20857-20858. PMID 22173637 DOI: 10.1073/pnas.1118443109  1
2011 Duan S, Skaar JR, Kuchay S, Toschi A, Kanarek N, Ben-Neriah Y, Pagano M. mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR. Molecular Cell. 44: 317-24. PMID 22017877 DOI: 10.1016/j.molcel.2011.09.005  0.56
2011 Pagan J, Pagano M. FBXW5 controls centrosome number Nature Cell Biology. 13: 888-890. PMID 21808243 DOI: 10.1038/ncb2312  1
2011 Cotto-Rios XM, Jones MJ, Busino L, Pagano M, Huang TT. APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage. The Journal of Cell Biology. 194: 177-86. PMID 21768287 DOI: 10.1083/jcb.201101062  0.56
2011 Millman SE, Pagano M. MCL1 meets its end during mitotic arrest Embo Reports. 12: 384-385. PMID 21475247 DOI: 10.1038/embor.2011.62  1
2011 Nguyen PL, Lin DI, Lei J, Fiorentino M, Mueller E, Weinstein MH, Pagano M, Loda M. The impact of Skp2 overexpression on recurrence-free survival following radical prostatectomy. Urologic Oncology. 29: 302-8. PMID 19450994 DOI: 10.1016/j.urolonc.2009.03.022  1
2010 Young LM, Pagano M. Cdc25 phosphatases: differential regulation by ubiquitin-mediated proteolysis. Cell Cycle (Georgetown, Tex.). 9: 4613-4. PMID 21260951 DOI: 10.4161/cc.9.23.13934  1
2010 D'Angiolella V, Donato V, Vijayakumar S, Saraf A, Florens L, Washburn MP, Dynlacht B, Pagano M. SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. Nature. 466: 138-42. PMID 20596027 DOI: 10.1038/nature09140  1
2010 Kanarek N, Horwitz E, Mayan I, Leshets M, Cojocaru G, Davis M, Tsuberi BZ, Pikarsky E, Pagano M, Ben-Neriah Y. Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion. Genes & Development. 24: 470-7. PMID 20194439 DOI: 10.1101/gad.551610  1
2010 Skaar JR, Pagano M. Spindle assembly checkpoint inactivation: a new role for phosphatases. Cell Cycle (Georgetown, Tex.). 9: 644-5. PMID 20190575  1
2010 Ligr M, Li Y, Zou X, Daniels G, Melamed J, Peng Y, Wang W, Wang J, Ostrer H, Pagano M, Wang Z, Garabedian MJ, Lee P. Tumor suppressor function of androgen receptor coactivator ARA70alpha in prostate cancer. The American Journal of Pathology. 176: 1891-900. PMID 20167864 DOI: 10.2353/ajpath.2010.090293  1
2010 Bashir T, Pagan JK, Busino L, Pagano M. Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization. Cell Cycle (Georgetown, Tex.). 9: 971-4. PMID 20160477 DOI: 10.4161/cc.9.5.10914  0.56
2009 Skaar JR, Richard DJ, Saraf A, Toschi A, Bolderson E, Florens L, Washburn MP, Khanna KK, Pagano M. INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology. 187: 25-32. PMID 19786574 DOI: 10.1083/jcb.200907026  1
2009 Skaar JR, Pagano M. Control of cell growth by the SCF and APC/C ubiquitin ligases. Current Opinion in Cell Biology. 21: 816-24. PMID 19775879 DOI: 10.1016/j.ceb.2009.08.004  1
2009 Skaar JR, D'Angiolella V, Pagan JK, Pagano M. SnapShot: F Box Proteins II. Cell. 137: 1358, 1358.e1. PMID 19563764 DOI: 10.1016/j.cell.2009.05.040  1
2009 Skaar JR, Pagan JK, Pagano M. SnapShot: F box proteins I. Cell. 137: 1160-1160.e1. PMID 19524517 DOI: 10.1016/j.cell.2009.05.039  1
2009 Dehan E, Bassermann F, Guardavaccaro D, Vasiliver-Shamis G, Cohen M, Lowes KN, Dustin M, Huang DC, Taunton J, Pagano M. betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. Molecular Cell. 33: 109-16. PMID 19150432 DOI: 10.1016/j.molcel.2008.12.020  1
2009 Ge S, Skaar JR, Pagano M. APC/C- and Mad2-mediated degradation of Cdc20 during spindle checkpoint activation. Cell Cycle (Georgetown, Tex.). 8: 167-71. PMID 19098431  1
2008 Frescas D, Guardavaccaro D, Kuchay SM, Kato H, Poleshko A, Basrur V, Elenitoba-Johnson KS, Katz RA, Pagano M. KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state Cell Cycle. 7: 3539-3547. PMID 19001877  1
2008 Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes & Development. 22: 2496-506. PMID 18794347 DOI: 10.1101/gad.1676108  0.48
2008 Bassermann F, Frescas D, Guardavaccaro D, Busino L, Peschiaroli A, Pagano M. The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Cell. 134: 256-67. PMID 18662541 DOI: 10.1016/j.cell.2008.05.043  0.56
2008 Skaar JR, Pagano M. Cdh1: a master G0/G1 regulator. Nature Cell Biology. 10: 755-7. PMID 18591966 DOI: 10.1038/ncb0708-755  1
2008 Frescas D, Pagano M. Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: Tipping the scales of cancer Nature Reviews Cancer. 8: 438-449. PMID 18500245 DOI: 10.1038/nrc2396  1
2008 Zhao X, Heng JI, Guardavaccaro D, Jiang R, Pagano M, Guillemot F, Iavarone A, Lasorella A. The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nature Cell Biology. 10: 643-53. PMID 18488021 DOI: 10.1038/ncb1727  1
2008 Michaelson D, Abidi W, Guardavaccaro D, Zhou M, Ahearn I, Pagano M, Philips MR. Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division. The Journal of Cell Biology. 181: 485-96. PMID 18443222 DOI: 10.1083/jcb.200801047  1
2008 Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M. Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature. 452: 365-9. PMID 18354482 DOI: 10.1038/nature06641  0.48
2008 Peng Y, Li CX, Chen F, Wang Z, Ligr M, Melamed J, Wei J, Gerald W, Pagano M, Garabedian MJ, Lee P. Stimulation of prostate cancer cellular proliferation and invasion by the androgen receptor co-activator ARA70. The American Journal of Pathology. 172: 225-35. PMID 18156210 DOI: 10.2353/ajpath.2008.070065  1
2007 Cardozo T, Pagano M. Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes. Bmc Biochemistry. 8: S9. PMID 18047746 DOI: 10.1186/1471-2091-8-S1-S9  1
2007 Frescas D, Guardavaccaro D, Bassermann F, Koyama-Nasu R, Pagano M. JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes. Nature. 450: 309-13. PMID 17994099 DOI: 10.1038/nature06255  0.48
2007 Amador V, Ge S, Santamaría PG, Guardavaccaro D, Pagano M. APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase. Molecular Cell. 27: 462-73. PMID 17679094 DOI: 10.1016/j.molcel.2007.06.013  0.56
2007 Godinho SI, Maywood ES, Shaw L, Tucci V, Barnard AR, Busino L, Pagano M, Kendall R, Quwailid MM, Romero MR, O'neill J, Chesham JE, Brooker D, Lalanne Z, Hastings MH, et al. The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science (New York, N.Y.). 316: 897-900. PMID 17463252 DOI: 10.1126/science.1141138  1
2007 Busino L, Bassermann F, Maiolica A, Lee C, Nolan PM, Godinho SI, Draetta GF, Pagano M. SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science (New York, N.Y.). 316: 900-4. PMID 17463251 DOI: 10.1126/science.1141194  0.56
2007 Fielenbach N, Guardavaccaro D, Neubert K, Chan T, Li D, Feng Q, Hutter H, Pagano M, Antebi A. DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age. Developmental Cell. 12: 443-55. PMID 17336909 DOI: 10.1016/j.devcel.2007.01.018  0.48
2007 Santamaría PG, Pagano M. The pRb-Cdh1-p27 autoamplifying network. Nature Cell Biology. 9: 137-8. PMID 17268477 DOI: 10.1038/ncb0207-137  1
2006 Dorrello NV, Peschiaroli A, Guardavaccaro D, Colburn NH, Sherman NE, Pagano M. S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science (New York, N.Y.). 314: 467-71. PMID 17053147 DOI: 10.1126/science.1130276  1
2006 Peschiaroli A, Dorrello NV, Guardavaccaro D, Venere M, Halazonetis T, Sherman NE, Pagano M. SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Molecular Cell. 23: 319-29. PMID 16885022 DOI: 10.1016/j.molcel.2006.06.013  0.48
2006 Utku Y, Dehan E, Ouerfelli O, Piano F, Zuckermann RN, Pagano M, Kirshenbaum K. A peptidomimetic siRNA transfection reagent for highly effective gene silencing. Molecular Biosystems. 2: 312-7. PMID 16880950 DOI: 10.1039/b603229j  1
2006 Lasorella A, Stegmüller J, Guardavaccaro D, Liu G, Carro MS, Rothschild G, de la Torre-Ubieta L, Pagano M, Bonni A, Iavarone A. Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature. 442: 471-4. PMID 16810178 DOI: 10.1038/nature04895  1
2006 Ji P, Goldin L, Ren H, Sun D, Guardavaccaro D, Pagano M, Zhu L. Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1. The Journal of Biological Chemistry. 281: 24058-69. PMID 16774918 DOI: 10.1074/jbc.M603105200  0.48
2006 Guardavaccaro D, Pagano M. Stabilizers and Destabilizers Controlling Cell Cycle Oscillators Molecular Cell. 22: 1-4. PMID 16600864 DOI: 10.1016/j.molcel.2006.03.017  1
2005 Bloom J, Pagano M. Experimental tests to definitively determine ubiquitylation of a substrate Methods in Enzymology. 399: 249-266. PMID 16338361 DOI: 10.1016/S0076-6879(05)99017-4  1
2005 Hao B, Zheng N, Schulman BA, Wu G, Miller JJ, Pagano M, Pavletich NP. Structural basis of the Cks1-dependent recognition of p27 Kip1 by the SCF Skp2 ubiquitin ligase Molecular Cell. 20: 9-19. PMID 16209941 DOI: 10.1016/j.molcel.2005.09.003  1
2005 Block K, Appikonda S, Lin HR, Bloom J, Pagano M, Yew PR. The acidic tail domain of human Cdc34 is required for p27Kip1 ubiquitination and complementation of a cdc34 temperature sensitive yeast strain. Cell Cycle (Georgetown, Tex.). 4: 1421-7. PMID 16123592  1
2005 Benmaamar R, Pagano M. Involvement of the SCF complex in the control of Cdh1 degradation in S-phase Cell Cycle. 4: 1230-1232. PMID 16123585  1
2005 Bashir T, Pagano M. Cdk1: The dominant sibling of Cdk2 Nature Cell Biology. 7: 779-781. PMID 16056272 DOI: 10.1038/ncb0805-779  1
2005 Dehan E, Pagano M. Skp2, the FoxO1 hunter Cancer Cell. 7: 209-210. PMID 15766658 DOI: 10.1016/j.ccr.2005.02.014  1
2004 Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, ... ... Pagano M, et al. Varshavsky's contributions. Science (New York, N.Y.). 306: 1290-2. PMID 15550643 DOI: 10.1126/science.306.5700.1290  1
2004 Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW. Systematic analysis and nomenclature of mammalian F-box proteins. Genes & Development. 18: 2573-80. PMID 15520277 DOI: 10.1101/gad.1255304  1
2004 Cardozo T, Pagano M. The SCF ubiquitin ligase: insights into a molecular machine. Nature Reviews. Molecular Cell Biology. 5: 739-51. PMID 15340381 DOI: 10.1038/nrm1471  1
2004 Kudo Y, Guardavaccaro D, Santamaria PG, Koyama-Nasu R, Latres E, Bronson R, Yamasaki L, Pagano M. Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis. Molecular and Cellular Biology. 24: 8184-94. PMID 15340078 DOI: 10.1128/MCB.24.18.8184-8194.2004  0.48
2004 Pagano M, Jackson PK. Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. Cell. 118: 535-8. PMID 15339658 DOI: 10.1016/j.cell.2004.08.013  1
2004 Bashir T, Pagano M. Don't skip the G1 phase: How APC/CCdh1 keeps SCF Skp2 in check Cell Cycle. 3: 850-852. PMID 15190201  1
2004 Pagano M. Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis Molecular Cell. 14: 414-416. PMID 15149588 DOI: 10.1016/S1097-2765(04)00268-0  1
2004 Moshe Y, Boulaire J, Pagano M, Hershko A. Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome. Proceedings of the National Academy of Sciences of the United States of America. 101: 7937-42. PMID 15148369 DOI: 10.1073/pnas.0402442101  1
2004 Guardavaccaro D, Pagano M. Oncogenic aberrations of cullin-dependent ubiquitin ligases Oncogene. 23: 2037-2049. PMID 15021891 DOI: 10.1038/sj.onc.1207413  1
2003 Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, Dorrello NV, Hershko A, Pagano M, Draetta GF. Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature. 426: 87-91. PMID 14603323 DOI: 10.1038/nature02082  1
2003 Pagano M, Benmaamar R. When protein destruction runs amok, malignancy is on the loose Cancer Cell. 4: 251-256. PMID 14585352 DOI: 10.1016/S1535-6108(03)00243-5  1
2003 Bloom J, Amador V, Bartolini F, DeMartino G, Pagano M. Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation. Cell. 115: 71-82. PMID 14532004 DOI: 10.1016/S0092-8674(03)00755-4  1
2003 Guardavaccaro D, Kudo Y, Boulaire J, Barchi M, Busino L, Donzelli M, Margottin-Goguet F, Jackson PK, Yamasaki L, Pagano M. Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo. Developmental Cell. 4: 799-812. PMID 12791266 DOI: 10.1016/S1534-5807(03)00154-0  1
2003 Bornstein G, Bloom J, Sitry-Shevah D, Nakayama K, Pagano M, Hershko A. Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase. The Journal of Biological Chemistry. 278: 25752-7. PMID 12730199 DOI: 10.1074/jbc.M301774200  1
2003 Bashir T, Pagano M. Aberrant ubiquitin-mediated proteolysis of cell cycle regulatory proteins and oncogenesis Advances in Cancer Research. 88: 101-144. PMID 12665054 DOI: 10.1016/S0065-230X(03)88305-7  1
2003 Bloom J, Pagano M. Deregulated degradation of the cdk inhibitor p27 and malignant transformation Seminars in Cancer Biology. 13: 41-47. PMID 12507555 DOI: 10.1016/S1044-579X(02)00098-6  1
2002 Donzelli M, Squatrito M, Ganoth D, Hershko A, Pagano M, Draetta GF. Dual mode of degradation of Cdc25 A phosphatase. The Embo Journal. 21: 4875-84. PMID 12234927 DOI: 10.1093/emboj/cdf491  1
2002 Sitry D, Seeliger MA, Ko TK, Ganoth D, Breward SE, Itzhaki LS, Pagano M, Hershko A. Three different binding sites of Cks1 are required for p27-ubiquitin ligation. The Journal of Biological Chemistry. 277: 42233-40. PMID 12140288 DOI: 10.1074/jbc.M205254200  1
2002 Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex Nature. 416: 703-709. PMID 11961546 DOI: 10.1038/416703a  1
2001 DeSalle LM, Latres E, Lin D, Graner E, Montagnoli A, Baker RT, Pagano M, Loda M. The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein. Oncogene. 20: 5538-42. PMID 11571652 DOI: 10.1038/sj.onc.1204824  1
2001 Carrano AC, Pagano M. Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression Journal of Cell Biology. 153: 1381-1389. PMID 11425869 DOI: 10.1083/jcb.153.7.1381  1
2001 Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, Pagano M, Hershko A. The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nature Cell Biology. 3: 321-4. PMID 11231585 DOI: 10.1038/35060126  1
2001 DeSalle LM, Pagano M. Regulation of the G1 to S transition by the ubiquitin pathway Febs Letters. 490: 179-189. PMID 11223033 DOI: 10.1016/S0014-5793(01)02121-4  1
2000 Kipreos ET, Pagano M. The F-box protein family Genome Biology. 1. PMID 11178263 DOI: 10.1186/gb-2000-1-5-reviews3002  1
2000 Schulman BA, Carrano AC, Jeffrey PD, Bowen Z, Kinnucan ERE, Finnin MS, Elledge SJ, Harper JW, Pagano M, Pavletich NP. Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex Nature. 408: 381-386. PMID 11099048 DOI: 10.1038/35042620  1
1999 Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nature Cell Biology. 1: 193-9. PMID 10559916 DOI: 10.1038/12013  1
1999 Montagnoli A, Fiore F, Eytan E, Carrano AC, Draetta GF, Hershko A, Pagano M. Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes & Development. 13: 1181-9. PMID 10323868 DOI: 10.1101/gad.13.9.1181  1
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