Janet D. Sparks - Publications

University of Rochester, Rochester, NY 
Pathology, Cell Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Sparks CE, Sparks JD. Autophagy and hepatic steatosis. Current Opinion in Lipidology. 28: 383-384. PMID 28700380 DOI: 10.1097/MOL.0000000000000436  0.64
2016 Sparks RP, Jenkins JL, Miner GE, Wang Y, Guida WC, Sparks CE, Fratti RA, Sparks JD. Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding. Biochemical and Biophysical Research Communications. PMID 27666481 DOI: 10.1016/j.bbrc.2016.09.108  0.64
2016 Sparks RP, Guida WC, Sowden MP, Jenkins JL, Starr ML, Fratti RA, Sparks CE, Sparks JD. Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells. Biochemical and Biophysical Research Communications. PMID 27495870 DOI: 10.1016/j.bbrc.2016.07.096  0.64
2015 Sparks CE, Sparks RP, Sparks JD. The enigmatic role of sortilin in lipoprotein metabolism. Current Opinion in Lipidology. 26: 598-600. PMID 26780014 DOI: 10.1097/MOL.0000000000000244  0.36
2015 Sparks JD, Magra AL, Chamberlain JM, O'Dell C, Sparks CE. Insulin dependent apolipoprotein B degradation and phosphatidylinositide 3-kinase activation with microsomal translocation are restored in McArdle RH7777 cells following serum deprivation. Biochemical and Biophysical Research Communications. PMID 26616056 DOI: 10.1016/j.bbrc.2015.11.068  0.36
2014 Yu IC, Lin HY, Sparks JD, Yeh S, Chang C. Androgen receptor roles in insulin resistance and obesity in males: the linkage of androgen-deprivation therapy to metabolic syndrome. Diabetes. 63: 3180-8. PMID 25249645 DOI: 10.2337/db13-1505  0.36
2014 Sparks CE, Corsetti JP, Sparks JD. High-density lipoproteins: taking the good with the bad. Current Opinion in Lipidology. 25: 230-2. PMID 24763089 DOI: 10.1097/MOL.0000000000000079  0.36
2014 Huang CK, Pang H, Wang L, Niu Y, Luo J, Chang E, Sparks JD, Lee SO, Chang C. New therapy via targeting androgen receptor in monocytes/macrophages to battle atherosclerosis. Hypertension. 63: 1345-53. PMID 24688120 DOI: 10.1161/HYPERTENSIONAHA.113.02804  0.36
2013 Sparks CE, Sparks JD. Hepatic postprandial transition and very low-density lipoprotein biogenesis. Current Opinion in Lipidology. 24: 450-2. PMID 24005219 DOI: 10.1097/MOL.0b013e3283654ed0  0.36
2013 Sparks JD, O'Dell C, Chamberlain JM, Sparks CE. Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases. Biochemical and Biophysical Research Communications. 435: 616-20. PMID 23685141 DOI: 10.1016/j.bbrc.2013.05.029  0.36
2013 Chamberlain JM, O'Dell C, Sparks CE, Sparks JD. Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting. Biochemical and Biophysical Research Communications. 430: 66-71. PMID 23159624 DOI: 10.1016/j.bbrc.2012.11.022  0.36
2013 Yu IC, Lin HY, Liu NC, Sparks JD, Yeh S, Fang LY, Chen L, Chang C. Neuronal androgen receptor regulates insulin sensitivity via suppression of hypothalamic NF-κB-mediated PTP1B expression. Diabetes. 62: 411-23. PMID 23139353 DOI: 10.2337/db12-0135  0.36
2012 Sparks CE, Sparks JD. Hepatic steatosis and VLDL hypersecretion. Current Opinion in Lipidology. 23: 395-7. PMID 22801389 DOI: 10.1097/MOL.0b013e3283555afa  0.36
2012 Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2104-12. PMID 22796579 DOI: 10.1161/ATVBAHA.111.241463  0.36
2011 Kim E, Liu NC, Yu IC, Lin HY, Lee YF, Sparks JD, Chen LM, Chang C. Metformin inhibits nuclear receptor TR4-mediated hepatic stearoyl-CoA desaturase 1 gene expression with altered insulin sensitivity. Diabetes. 60: 1493-503. PMID 21478464 DOI: 10.2337/db10-0393  0.36
2011 Sparks JD, Chamberlain JM, O'Dell C, Khatun I, Hussain MM, Sparks CE. Acute suppression of apo B secretion by insulin occurs independently of MTP. Biochemical and Biophysical Research Communications. 406: 252-6. PMID 21316344 DOI: 10.1016/j.bbrc.2011.02.028  0.64
2010 Sparks JD, Cianci J, Jokinen J, Chen LS, Sparks CE. Interleukin-6 mediates hepatic hypersecretion of apolipoprotein B. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G980-9. PMID 20651008 DOI: 10.1152/ajpgi.00080.2010  0.64
2010 Galloway CA, Ashton J, Sparks JD, Mooney RA, Smith HC. Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes. Biochimica Et Biophysica Acta. 1802: 976-85. PMID 20541607 DOI: 10.1016/j.bbadis.2010.06.003  0.36
2010 Sparks CE, Sparks JD. Lipid metabolism: insights into the complexity of VLDL metabolic pathways. Current Opinion in Lipidology. 21: 280-1. PMID 20463474 DOI: 10.1097/MOL.0b013e3283399aa2  0.36
2009 Caviglia JM, Sparks JD, Toraskar N, Brinker AM, Yin TC, Dixon JL, Brasaemle DL. ABHD5/CGI-58 facilitates the assembly and secretion of apolipoprotein B lipoproteins by McA RH7777 rat hepatoma cells. Biochimica Et Biophysica Acta. 1791: 198-205. PMID 19211039 DOI: 10.1016/j.bbalip.2008.12.018  0.36
2008 Sparks JD, Sparks CE. Overindulgence and metabolic syndrome: is FoxO1 a missing link? The Journal of Clinical Investigation. 118: 2012-5. PMID 18497882 DOI: 10.1172/JCI35693  0.36
2008 Lin HY, Yu IC, Wang RS, Chen YT, Liu NC, Altuwaijri S, Hsu CL, Ma WL, Jokinen J, Sparks JD, Yeh S, Chang C. Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor. Hepatology (Baltimore, Md.). 47: 1924-35. PMID 18449947 DOI: 10.1002/hep.22252  0.36
2008 Yu IC, Lin HY, Liu NC, Wang RS, Sparks JD, Yeh S, Chang C. Hyperleptinemia without obesity in male mice lacking androgen receptor in adipose tissue. Endocrinology. 149: 2361-8. PMID 18276764 DOI: 10.1210/en.2007-0516  0.36
2007 Liu NC, Lin WJ, Kim E, Collins LL, Lin HY, Yu IC, Sparks JD, Chen LM, Lee YF, Chang C. Loss of TR4 orphan nuclear receptor reduces phosphoenolpyruvate carboxykinase-mediated gluconeogenesis. Diabetes. 56: 2901-9. PMID 17827404 DOI: 10.2337/db07-0359  0.36
2006 Nieman KM, Hartz CS, Szegedi SS, Garrow TA, Sparks JD, Schalinske KL. Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats. American Journal of Physiology. Endocrinology and Metabolism. 291: E1235-42. PMID 16835399 DOI: 10.1152/ajpendo.00237.2006  0.36
2006 Chirieac DV, Davidson NO, Sparks CE, Sparks JD. PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G382-8. PMID 16798720 DOI: 10.1152/ajpgi.00472.2005  0.64
2006 Sparks JD, Collins HL, Chirieac DV, Cianci J, Jokinen J, Sowden MP, Galloway CA, Sparks CE. Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase. The Biochemical Journal. 395: 363-71. PMID 16396637 DOI: 10.1042/BJ20051966  0.64
2004 Chirieac DV, Collins HL, Cianci J, Sparks JD, Sparks CE. Altered triglyceride-rich lipoprotein production in Zucker diabetic fatty rats. American Journal of Physiology. Endocrinology and Metabolism. 287: E42-9. PMID 14970003 DOI: 10.1152/ajpendo.00297.2003  0.64
2004 Au CS, Wagner A, Chong T, Qiu W, Sparks JD, Adeli K. Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBalpha. Metabolism: Clinical and Experimental. 53: 228-35. PMID 14767876 DOI: 10.1016/j.metabol.2003.09.011  0.36
2002 Chirieac DV, Cianci J, Collins HL, Sparks JD, Sparks CE. Insulin suppression of VLDL apo B secretion is not mediated by the LDL receptor. Biochemical and Biophysical Research Communications. 297: 134-7. PMID 12220520  0.64
2000 Collins HL, Sparks CE, Sparks JD. B48 is preferentially translated over B100 in cells with increased endogenous apo B mRNA. Biochemical and Biophysical Research Communications. 273: 1156-60. PMID 10891388 DOI: 10.1006/bbrc.2000.3074  0.64
1999 Sowden MP, Collins HL, Smith HC, Garrow TA, Sparks JD, Sparks CE. Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase. The Biochemical Journal. 341: 639-45. PMID 10417327 DOI: 10.1042/0264-6021:3410639  0.36
1997 Sparks JD, Collins HL, Sabio I, Sowden MP, Smith HC, Cianci J, Sparks CE. Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells. Biochimica Et Biophysica Acta. 1347: 51-61. PMID 9233686  0.64
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