| Year |
Citation |
Score |
| 2022 |
Chen FW, Davies JP, Calvo R, Chaudhari J, Dolios G, Taylor MK, Patnaik S, Dehdashti J, Mull R, Dranchack P, Wang A, Xu X, Hughes E, Southall N, Ferrer M, ... ... Ioannou YA, et al. Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction. Iscience. 25: 104941. PMID 36065186 DOI: 10.1016/j.isci.2022.104941 |
0.544 |
|
| 2019 |
Robinson G, Radziszewska A, Wincup C, Ciurtin C, Ioannou Y, Torra IP, Jury E, Lab J. Op0148 Metabolomics In Juvenile-Onset Sle: Identifying New Biomarkers To Predict Cardiovascular Risk Annals of the Rheumatic Diseases. 78: 149-150. DOI: 10.1136/Annrheumdis-2019-Eular.4067 |
0.323 |
|
| 2018 |
Wincup C, Ioannou Y. The Differences Between Childhood and Adult Onset Antiphospholipid Syndrome. Frontiers in Pediatrics. 6: 362. PMID 30542645 DOI: 10.3389/Fped.2018.00362 |
0.303 |
|
| 2018 |
McDonnell TCR, Willis R, Pericleous C, Ripoll VM, Giles IP, Isenberg DA, Brasier AR, Gonzalez EB, Papalardo E, Romay-Penabad Z, Jamaluddin M, Ioannou Y, Rahman A. PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome. Frontiers in Immunology. 9: 2413. PMID 30405613 DOI: 10.3389/Fimmu.2018.02413 |
0.331 |
|
| 2018 |
Robinson G, Pineda-Torra I, Ioannou Y, Jury E. PS5:87 Juvenile-onset sle immunopathogenesis could be associated with altered immune cell plasma membrane lipids and lipoprotein metabolism Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Abstract.132 |
0.36 |
|
| 2016 |
Munkacsi AB, Hammond N, Schneider RT, Senanayake DS, Higaki K, Lagutin K, Bloor SJ, Ory DS, Maue RA, Chen FW, Hernandez-Ono A, Dahlson N, Repa JJ, Ginsberg HN, Ioannou YA, et al. Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat. The Journal of Biological Chemistry. PMID 28031458 DOI: 10.1074/Jbc.M116.770578 |
0.621 |
|
| 2015 |
Croca S, Bassett P, Chambers S, Davari M, Alber KF, Leach O, Ioannou Y, Giles I, Isenberg D, Rahman A. IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. Arthritis Research & Therapy. 17: 26. PMID 25890187 DOI: 10.1186/S13075-015-0539-Z |
0.308 |
|
| 2014 |
Ripoll VM, Lambrianides A, Pierangeli SS, Poulton K, Ioannou Y, Heywood WE, Mills K, Latchman DS, Isenberg DA, Rahman A, Giles IP. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. Blood. 124: 3808-16. PMID 25301710 DOI: 10.1182/Blood-2014-05-577569 |
0.33 |
|
| 2013 |
Tamari F, Chen FW, Li C, Chaudhari J, Ioannou YA. PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport. Plos One. 8: e74169. PMID 23977398 DOI: 10.1371/Journal.Pone.0074169 |
0.631 |
|
| 2012 |
Liapis A, Chen FW, Davies JP, Wang R, Ioannou YA. MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site Plos One. 7. PMID 22514632 DOI: 10.1371/Journal.Pone.0034424 |
0.741 |
|
| 2012 |
Ioannou Y. The Michael Mason prize: Pathogenic antiphospholipid antibodies, stressed out antigens and the deployment of decoys Rheumatology. 51: 32-36. PMID 22120465 DOI: 10.1093/Rheumatology/Ker353 |
0.301 |
|
| 2012 |
Heathfield S, Parker B, Zeef L, Bruce I, Alexander Y, Collins F, Stone M, Wang E, Williams AS, Wright HL, Thomas HB, Moots RJ, Edwards SW, Bullock C, Chapman V, ... ... Ioannou Y, et al. Basic science232. Certolizumab pegol prevents pro-inflammatory alterations in endothelial cell function Rheumatology. 51. DOI: 10.1093/Rheumatology/Kes108 |
0.315 |
|
| 2011 |
Ioannou Y, Zhang JY, Qi M, Gao L, Qi JC, Yu DM, Lau H, Sturgess AD, Vlachoyiannopoulos PG, Moutsopoulos HM, Rahman A, Pericleous C, Atsumi T, Koike T, Heritier S, et al. Novel assays of thrombogenic pathogenicity in the antiphospholipid syndrome based on the detection of molecular oxidative modification of the major autoantigen β2-glycoprotein I. Arthritis and Rheumatism. 63: 2774-82. PMID 21618459 DOI: 10.1002/Art.30383 |
0.328 |
|
| 2011 |
Munkacsi AB, Chen FW, Brinkman MA, Higaki K, Gutiérrez GD, Chaudhari J, Layer JV, Tong A, Bard M, Boone C, Ioannou YA, Sturley SL. An "exacerbate-reverse" strategy in yeast identifies histone deacetylase inhibition as a correction for cholesterol and sphingolipid transport defects in human Niemann-Pick type C disease. The Journal of Biological Chemistry. 286: 23842-51. PMID 21489983 DOI: 10.1074/Jbc.M111.227645 |
0.619 |
|
| 2010 |
Chen FW, Li C, Ioannou YA. Cyclodextrin induces calcium-dependent lysosomal exocytosis. Plos One. 5: e15054. PMID 21124786 DOI: 10.1371/Journal.Pone.0015054 |
0.59 |
|
| 2010 |
Ioannou Y, Rahman A. Domain I of β2-glycoprotein I: its role as an epitope and the potential to be developed as a specific target for the treatment of the antiphospholipid syndrome Lupus. 19: 400-405. PMID 20353977 DOI: 10.1177/0961203309360544 |
0.315 |
|
| 2009 |
Temel RE, Brown JM, Ma Y, Tang W, Rudel LL, Ioannou YA, Davies JP, Yu L. Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent Journal of Lipid Research. 50: 915-923. PMID 19141868 DOI: 10.1194/Jlr.M800631-Jlr200 |
0.31 |
|
| 2009 |
Walter M, Chen FW, Tamari F, Wang R, Ioannou YA. Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 101: 141-52. PMID 18681838 DOI: 10.1042/Bc20070171 |
0.608 |
|
| 2008 |
Tang W, Ma Y, Jia L, Ioannou YA, Davies JP, Yu L. Niemann-pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 448-454. PMID 18187667 DOI: 10.1161/Atvbaha.107.160465 |
0.309 |
|
| 2007 |
Knöpfel M, Davies JP, Duong PT, Kvaernø L, Carreira EM, Phillips MC, Ioannou YA, Hauser H. Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane. Biochimica Et Biophysica Acta. 1771: 1140-7. PMID 17689140 DOI: 10.1016/J.Bbalip.2007.05.011 |
0.331 |
|
| 2007 |
Temel RE, Tang W, Ma Y, Rudel LL, Willingham MC, Ioannou YA, Davies JP, Nilsson LM, Yu L. Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe Journal of Clinical Investigation. 117: 1968-1978. PMID 17571164 DOI: 10.1172/Jci30060 |
0.314 |
|
| 2007 |
Labonté ED, Howles PN, Granholm NA, Rojas JC, Davies JP, Ioannou YA, Hui DY. Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1771: 1132-1139. PMID 17442616 DOI: 10.1016/J.Bbalip.2007.03.002 |
0.324 |
|
| 2007 |
Ioannou YA. Niemann-Pick C proteins in sterol transport and absorption: flies in the ointment. Developmental Cell. 12: 481-3. PMID 17419988 DOI: 10.1016/J.Devcel.2007.03.017 |
0.317 |
|
| 2007 |
Suzuki M, Sugimoto Y, Ohsaki Y, Ueno M, Kato S, Kitamura Y, Hosokawa H, Davies JP, Ioannou YA, Vanier MT, Ohno K, Ninomiya H. Endosomal accumulation of Toll-like receptor 4 causes constitutive secretion of cytokines and activation of signal transducers and activators of transcription in Niemann-Pick disease type C (NPC) fibroblasts: a potential basis for glial cell activation in the NPC brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1879-91. PMID 17314284 DOI: 10.1523/Jneurosci.5282-06.2007 |
0.316 |
|
| 2006 |
Ohsaki Y, Sugimoto Y, Suzuki M, Hosokawa H, Yoshimori T, Davies JP, Ioannou YA, Vanier MT, Ohno K, Ninomiya H. Cholesterol depletion facilitates ubiquitylation of NPC1 and its association with SKD1/Vps4. Journal of Cell Science. 119: 2643-53. PMID 16757520 DOI: 10.1242/Jcs.02993 |
0.368 |
|
| 2006 |
Davies JP, Ioannou YA. The role of the Niemann-Pick C1-like 1 protein in the subcellular transport of multiple lipids and their homeostasis Current Opinion in Lipidology. 17: 221-226. PMID 16680025 DOI: 10.1097/01.Mol.0000226112.12684.5E |
0.331 |
|
| 2005 |
Ioannou YA. Guilty until proven innocent: the case of NPC1 and cholesterol. Trends in Biochemical Sciences. 30: 498-505. PMID 16054367 DOI: 10.1016/J.Tibs.2005.07.007 |
0.346 |
|
| 2005 |
Chen FW, Gordon RE, Ioannou YA. NPC1 late endosomes contain elevated levels of non-esterified ('free') fatty acids and an abnormally glycosylated form of the NPC2 protein. The Biochemical Journal. 390: 549-61. PMID 15896196 DOI: 10.1042/Bj20050236 |
0.646 |
|
| 2005 |
Davies JP, Scott C, Oishi K, Liapis A, Ioannou YA. Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia Journal of Biological Chemistry. 280: 12710-12720. PMID 15671032 DOI: 10.1074/Jbc.M409110200 |
0.754 |
|
| 2004 |
Scott C, Ioannou YA. The NPC1 protein: structure implies function. Biochimica Et Biophysica Acta. 1685: 8-13. PMID 15465421 DOI: 10.1016/J.Bbalip.2004.08.006 |
0.358 |
|
| 2004 |
Scott C, Higgins ME, Davies JP, Ioannou YA. Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain Journal of Biological Chemistry. 279: 48214-48233. PMID 15347664 DOI: 10.1074/Jbc.M406090200 |
0.669 |
|
| 2004 |
Ohsaki Y, Sugimoto Y, Suzuki M, Kaidoh T, Shimada Y, Ohno-Iwashita Y, Davies JP, Ioannou YA, Ohno K, Ninomiya H. Reduced sensitivity of Niemann-Pick C1-deficient cells to θ-toxin (perfringolysin O): Sequestration of toxin to raft-enriched membrane vesicles Histochemistry and Cell Biology. 121: 263-272. PMID 15069562 DOI: 10.1007/S00418-004-0643-7 |
0.328 |
|
| 2003 |
Ioannou YA, Enriquez A, Benjamin C. Gene therapy for lysosomal storage disorders. Expert Opinion On Biological Therapy. 3: 789-801. PMID 12880379 DOI: 10.1517/14712598.3.5.789 |
0.695 |
|
| 2003 |
Walter M, Davies JP, Ioannou YA. Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes Journal of Lipid Research. 44: 243-253. PMID 12576506 DOI: 10.1194/Jlr.M200230-Jlr200 |
0.359 |
|
| 2001 |
Higgins ME, Ioannou YA. Apoptosis-induced release of mature sterol regulatory element-binding proteins activates sterol-responsive genes. Journal of Lipid Research. 42: 1939-46. PMID 11734566 |
0.651 |
|
| 2001 |
Sugimoto Y, Ninomiya H, Ohsaki Y, Higaki K, Davies JP, Ioannou YA, Ohno K. Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemann-Pick C1-deficient cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 12391-6. PMID 11675488 DOI: 10.1073/Pnas.221181998 |
0.348 |
|
| 2001 |
Ioannou YA. Multidrug permeases and subcellular cholesterol transport. Nature Reviews. Molecular Cell Biology. 2: 657-68. PMID 11533723 DOI: 10.1038/35089558 |
0.355 |
|
| 2000 |
Davies JP, Chen FW, Ioannou YA. Transmembrane molecular pump activity of Niemann-Pick C1 protein. Science (New York, N.Y.). 290: 2295-8. PMID 11125140 DOI: 10.1126/Science.290.5500.2295 |
0.628 |
|
| 2000 |
Ioannou YA. The structure and function of the Niemann-Pick C1 protein. Molecular Genetics and Metabolism. 71: 175-81. PMID 11001808 DOI: 10.1006/Mgme.2000.3061 |
0.376 |
|
| 2000 |
Davies JP, Ioannou YA. Topological analysis of Niemann-Pick C1 protein reveals that the membrane orientation of the putative sterol-sensing domain is identical to those of 3-hydroxy-3-methylglutaryl-CoA reductase and sterol regulatory element binding protein cleavage-activating protein. The Journal of Biological Chemistry. 275: 24367-74. PMID 10821832 DOI: 10.1074/Jbc.M002184200 |
0.335 |
|
| 2000 |
Davies JP, Levy B, Ioannou YA. Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1. Genomics. 65: 137-45. PMID 10783261 DOI: 10.1006/Geno.2000.6151 |
0.364 |
|
| 1999 |
Chen FW, Ioannou YA. Ribosomal proteins in cell proliferation and apoptosis. International Reviews of Immunology. 18: 429-48. PMID 10672495 DOI: 10.3109/08830189909088492 |
0.601 |
|
| 1999 |
Higgins ME, Davies JP, Chen FW, Ioannou YA. Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network. Molecular Genetics and Metabolism. 68: 1-13. PMID 10479477 DOI: 10.1006/Mgme.1999.2882 |
0.76 |
|
| 1999 |
Ziegler RJ, Yew NS, Li C, Cherry M, Berthelette P, Romanczuk H, Ioannou YA, Zeidner KM, Desnick RJ, Cheng SH. Correction of enzymatic and lysosomal storage defects in Fabry mice by adenovirus-mediated gene transfer. Human Gene Therapy. 10: 1667-82. PMID 10428212 DOI: 10.1089/10430349950017671 |
0.319 |
|
| 1998 |
Chen FW, Davies JP, Ioannou YA. Differential gene expression in apoptosis: identification of ribosomal protein 23K, a cell proliferation inhibitor. Molecular Genetics and Metabolism. 64: 271-82. PMID 9758718 DOI: 10.1006/Mgme.1998.2718 |
0.597 |
|
| 1998 |
Rattazzi MC, Tsuda T, Benjamin CJ, Gordon RE, Friedrich VL, Desnick RJ, Ioannou YA. Delivery of Compacted DNA Across the Blood-Brain Barrier ♦ 732 Pediatric Research. 43: 127-127. DOI: 10.1203/00006450-199804001-00753 |
0.723 |
|
| 1997 |
Carstea ED, Morris JA, Coleman KG, Loftus SK, Zhang D, Cummings C, Gu J, Rosenfeld MA, Pavan WJ, Krizman DB, Nagle J, Polymeropoulos MH, Sturley SL, Ioannou YA, Higgins ME, et al. Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science (New York, N.Y.). 277: 228-31. PMID 9211849 DOI: 10.1126/Science.277.5323.228 |
0.683 |
|
| 1997 |
Davies JP, Cotter PD, Ioannou YA. Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene Genomics. 41: 131-134. PMID 9126495 DOI: 10.1006/Geno.1997.4644 |
0.315 |
|
| 1996 |
Ioannou YA, Chen FW. Quantitation of DNA fragmentation in apoptosis. Nucleic Acids Research. 24: 992-3. PMID 8600475 |
0.499 |
|
| 1995 |
Schuchman EH, Ioannou YA, Rattazzi MC, Desnick RJ. Neural gene therapy for inherited diseases with mental retardation: Principles and prospects Mental Retardation and Developmental Disabilities Research Reviews. 1: 39-48. DOI: 10.1002/Mrdd.1410010109 |
0.311 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2019 |
Wilkinson MGL, Radziszewska A, Wincup C, Ioannou Y, Isenberg DA, Manson JJ, Jury EC. Using peripheral blood immune signatures to stratify patients with adult and juvenile inflammatory myopathies. Rheumatology. 59: 194-204. PMID 31292651 DOI: 10.1093/Rheumatology/Kez252 |
0.299 |
|
| 2008 |
Ioannou Y, Lambrianides A, Cambridge G, Leandro MJ, Edwards JCW, Isenberg DA. B cell depletion therapy for patients with systemic lupus erythaematosus results in a significant drop in anticardiolipin antibody titres Annals of the Rheumatic Diseases. 67: 425-426. PMID 17905784 DOI: 10.1136/Ard.2007.078402 |
0.295 |
|
| 2011 |
Pericleous C, Miles J, Esposito D, Garza-Garcia A, Driscoll PC, Lambrianides A, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I. Evaluating the conformation of recombinant domain I of β(2)-glycoprotein I and its interaction with human monoclonal antibodies. Molecular Immunology. 49: 56-63. PMID 21899894 DOI: 10.1016/J.Molimm.2011.07.024 |
0.294 |
|
| 2014 |
Sangodkar J, Mazhar S, Wiredja D, Gokulrangan G, Schlatzer D, Kastrinsky D, Difeo A, Yao S, Izadmehr S, Sharma N, Ioannou Y, Ohlmeyer M, Narla G. Abstract A38: Therapeutic targeting of oncogenic KRAS signaling using a novel small molecule agonist of the PP2A tumor suppressor gene Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-A38 |
0.294 |
|
| 2018 |
Robinson G, Torra IP, Ioannou Y, Jury E. O30 The immunopathogenesis of juvenile-onset SLE could be associated with altered immune cell plasma membrane lipids and lipoprotein metabolism Rheumatology. 57. DOI: 10.1093/Rheumatology/Key075.212 |
0.293 |
|
| 2014 |
Croca S, Bassett P, Pericleous C, Alber KF, Latchman D, Isenberg D, Giles I, Rahman A, Ioannou Y. Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study. Arthritis Research & Therapy. 16: R48. PMID 24502558 DOI: 10.1186/Ar4477 |
0.293 |
|
| 2014 |
Pericleous C, Ripoll VM, Giles I, Ioannou Y. Laboratory tests for the antiphospholipid syndrome Methods of Molecular Biology. 1134: 221-235. PMID 24497366 DOI: 10.1007/978-1-4939-0326-9_17 |
0.292 |
|
| 2006 |
Ioannou Y, Giles I, Lambrianides A, Richardson C, Pearl LH, Latchman DS, Isenberg DA, Rahman A. A novel expression system of domain I of human beta2 glycoprotein I in Escherichia coli Bmc Biotechnology. 6. PMID 16472380 DOI: 10.1186/1472-6750-6-8 |
0.292 |
|
| 2017 |
Clark K, Josephs F, Daly N, Ioannou Y, Murphy C, Sen D. THU0516 Longer term outcomes of crmo in a tertiary adolescent and young adult rheumatology centre in the uk Annals of the Rheumatic Diseases. 76: 401-401. DOI: 10.1136/Annrheumdis-2017-Eular.5188 |
0.291 |
|
| 2015 |
Sangodkar J, McQuaid D, Kisselar J, Brautigan D, Chance M, Ohlmeyer M, Kastrinsky D, Ioannou Y, Narla G. Abstract B124: Drugging the undruggable: development of small molecule activators of protein phosphatase 2A for cancer treatment Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-B124 |
0.291 |
|
| 2010 |
Ioannou Y, Zhang J, Passam FH, Rahgozar S, Qi JC, Giannakopoulos B, Qi M, Yu P, Yu DM, Hogg PJ, Krilis SA. Naturally occurring free thiols within β2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress–induced cell injury Blood. 116: 1961-1970. PMID 20551379 DOI: 10.1182/Blood-2009-04-215335 |
0.291 |
|
| 2010 |
Pericleous C, Ioannou Y. New therapeutic targets for the antiphospholipid syndrome. Expert Opinion On Therapeutic Targets. 14: 1291-1299. PMID 20874375 DOI: 10.1517/14728222.2010.524207 |
0.291 |
|
| 2014 |
McDonnell T, Ioannou Y, Rahman A. PEGylated drugs in rheumatology--why develop them and do they work? Rheumatology (Oxford, England). 53: 391-6. PMID 23962623 DOI: 10.1093/Rheumatology/Ket278 |
0.29 |
|
| 2015 |
Rodríguez-García V, Ioannou Y, Fernández-Nebro A, Isenberg DA, Giles IP. Examining the prevalence of non-criteria anti-phospholipid antibodies in patients with anti-phospholipid syndrome: a systematic review Rheumatology. 54: 2042-2050. PMID 26152548 DOI: 10.1093/Rheumatology/Kev226 |
0.289 |
|
| 2015 |
Pericleous C, Ruiz-Limón P, Romay-Penabad Z, Marín AC, Garza-Garcia A, Murfitt L, Driscoll PC, Latchman DS, Isenberg DA, Giles I, Ioannou Y, Rahman A, Pierangeli SS. Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis. Rheumatology (Oxford, England). 54: 722-7. PMID 25273993 DOI: 10.1093/Rheumatology/Keu360 |
0.289 |
|
| 2017 |
Bourke LT, McDonnell T, McCormick J, Pericleous C, Ripoll VM, Giles I, Rahman A, Stephanou A, Ioannou Y. Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK. Cell Death & Disease. 8: e2549. PMID 28079888 DOI: 10.1038/Cddis.2016.235 |
0.287 |
|
| 2012 |
Watson L, Leone V, Pilkington C, Tullus K, Rangaraj S, McDonagh JE, Gardner-Medwin J, Wilkinson N, Riley P, Tizard J, Armon K, Sinha MD, Ioannou Y, Archer N, Bailey K, et al. Disease activity, severity, and damage in the UK Juvenile-Onset Systemic Lupus Erythematosus Cohort. Arthritis and Rheumatism. 64: 2356-65. PMID 22294381 DOI: 10.1002/Art.34410 |
0.287 |
|
| 2020 |
Robinson G, Peng J, Dönnes P, Coelewij L, Naja M, Radziszewska A, Wincup C, Peckham H, Isenberg D, Ioannou Y, Torra IP, Ciurtin C, Jury E. Op0287 A Machine Learning Approach For Precision Stratification Of Juvenile-Onset Sle Annals of the Rheumatic Diseases. 79: 179-179. DOI: 10.1136/Annrheumdis-2020-Eular.4167 |
0.287 |
|
| 1999 |
Ioannou Y, Sultan S, Isenberg DA. Myositis overlap syndromes. Current Opinion in Rheumatology. 11: 468-474. DOI: 10.1097/00002281-199911000-00004 |
0.286 |
|
| 2013 |
Pericleous C, Clarke LA, Brogan PA, Latchman DS, Isenberg DA, Ioannou Y, Giles IP, Rahman A. Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome Thrombosis and Haemostasis. 109: 72-78. PMID 23152159 DOI: 10.1160/Th12-05-0346 |
0.286 |
|
| 1999 |
Zeidner KM, Desnick RJ, Ioannou YA. Quantitative determination of globotriaosylceramide by immunodetection of glycolipid-bound recombinant verotoxin B subunit. Analytical Biochemistry. 267: 104-13. PMID 9918661 DOI: 10.1006/Abio.1998.2966 |
0.285 |
|
| 2014 |
Rodríguez-García V, Ioannou Y, Fernández-Nebro A, Isenberg DA, Giles I. AB0558 What is the Prevalence of NON Criteria Antiphospholipid Antibodies in Patients with Antiphospholipid Syndrome Annals of the Rheumatic Diseases. 73: 990-990. DOI: 10.1136/Annrheumdis-2014-Eular.2749 |
0.285 |
|
| 2017 |
Sangodkar J, Perl A, Tohme R, Kiselar J, Kastrinsky DB, Zaware N, Izadmehr S, Mazhar S, Wiredja DD, O'Connor CM, Hoon D, Dhawan NS, Schlatzer D, Yao S, Leonard D, ... ... Ioannou YA, et al. Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. The Journal of Clinical Investigation. PMID 28504649 DOI: 10.1172/Jci89548 |
0.282 |
|
| 2017 |
Shoop-Worrall SJ, Verstappen SM, Baildam E, Chieng A, Davidson J, Foster H, Ioannou Y, McErlane F, Wedderburn LR, Thomson W, Hyrich KL. How common is clinically inactive disease in a prospective cohort of patients with juvenile idiopathic arthritis? The importance of definition. Annals of the Rheumatic Diseases. PMID 28389553 DOI: 10.1136/Annrheumdis-2016-210511 |
0.281 |
|
| 1997 |
Ioannou YA, Zeidner KM, Friedman BA, Desnick RJ. Fabry disease: Effective tissue substrate depletion following enzyme replacement in α-galactosidase A deficient mice. • 607 Pediatric Research. 41: 104-104. DOI: 10.1203/00006450-199704001-00627 |
0.281 |
|
| 2017 |
Artim-Esen B, Smoktunowicz N, McDonnell T, Ripoll VM, Pericleous C, Mackie I, Robinson E, Isenberg D, Rahman A, Ioannou Y, Chambers RC, Giles I. Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome. Scientific Reports. 7: 10788. PMID 28883515 DOI: 10.1038/S41598-017-11315-9 |
0.281 |
|
| 2009 |
Ioannou Y, Romay-Penabad Z, Pericleous C, Giles I, Papalardo E, Vargas G, Shilagard T, Latchman DS, Isenberg DA, Rahman A, Pierangeli S. In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of β2-glycoprotein I: Proof of concept Journal of Thrombosis and Haemostasis. 7: 833-842. PMID 19220729 DOI: 10.1111/J.1538-7836.2009.03316.X |
0.28 |
|
| 2015 |
McDonnell T, Pericleous C, Laurine E, Tommasi R, Garza-Garcia A, Giles I, Ioannou Y, Rahman A. Development of a high yield expression and purification system for Domain I of Beta-2-glycoprotein I for the treatment of APS. Bmc Biotechnology. 15: 104. PMID 26576675 DOI: 10.1186/S12896-015-0222-0 |
0.278 |
|
| 2012 |
Lim D, Todd M, Kourtoglou N, Gerasimidis K, Gardner-Medwin J, Watson L, Tullus K, Pilkington C, Chesters C, Marks SD, Newland P, Jones C, Beresford MW, O’Neill P, Lee H, ... ... Ioannou Y, et al. BSPAR ANNUAL CONFERENCE ABSTRACTSOral presentationsO1. The impact of modern management on outcomes of JIA compared with healthy controls Rheumatology. 51. DOI: 10.1093/Rheumatology/Kes277 |
0.278 |
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| 2015 |
Sangodkar J, Izadmehr S, Mahzar S, Hoon D, Yao S, Kastrinsky D, Schlatzer D, Sharma N, Borczuk AC, Ohlmeyer M, Ioannou Y, Narla G. Abstract 5329: Development of small molecule activators of protein phosphatase 2A for the treatment of lung cancer Cancer Research. 75: 5329-5329. DOI: 10.1158/1538-7445.Am2015-5329 |
0.277 |
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| 2016 |
McDonnell TCR, Pericleous C, Giles I, Ioannou Y, Rahman A. 207 The Ability of Recombinant Domain I of BETA-2-Glycoprotein I to Inhibit the Lupus Anticoagulant Effect of IGG from Patients with Anti-Phospholipid Syndrome is Enhanced by Pegylation Rheumatology. 55. DOI: 10.1093/Rheumatology/Kew173.004 |
0.277 |
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| 2017 |
Raimondo MG, Pericleous C, Radziszewska A, Borghi MO, Pierangeli S, Meroni PL, Giles I, Rahman A, Ioannou Y. Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome. Plos One. 12: e0186513. PMID 29049363 DOI: 10.1371/Journal.Pone.0186513 |
0.275 |
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| 2015 |
Wu Q, Chaplin H, Ambrose N, Sen D, Leandro MJ, Wing C, Daly N, Webb K, Fisher C, Suffield L, Josephs F, Pilkington C, Eleftheriou D, Al-Obaidi M, Compeyrot-Lacassagne S, ... ... Ioannou Y, et al. Juvenile arthritis disease activity score is a better reflector of active disease than the disease activity score 28 in adults with polyarticular juvenile idiopathic arthritis. Annals of the Rheumatic Diseases. PMID 26715652 DOI: 10.1136/Annrheumdis-2015-208462 |
0.275 |
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| 2002 |
Stern AS, Klotman ME, Ioannou YA, Burrow CR, Wilson PD, Klotman PE, Lipkowitz MS. Polarity of alpha-galactosidase A uptake by renal tubule cells. Kidney International. 61: S52-5. PMID 11841613 DOI: 10.1046/J.1523-1755.2002.0610S1052.X |
0.274 |
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| 2002 |
Choy E, Isenberg DA, Garrood T, Farrow S, Ioannou Y, Bird H, Cheung N, Williams B, Hazleman B, Price R, Yoshizaki K, Nishimoto N, Kishimoto T, Panayi G. Therapeutic benefit of blocking interleukin‐6 activity with an anti–interleukin‐6 receptor monoclonal antibody in rheumatoid arthritis: A randomized, double‐blind, placebo‐controlled, dose‐escalation trial Arthritis & Rheumatism. 46: 3143-3150. PMID 12483717 DOI: 10.1002/Art.10623 |
0.274 |
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| 2016 |
Fisher C, Bourke L, Radziszewska A, Jadon D, Sengupta R, Bray T, Hall-Craggs M, Sen D, Ioannou Y. THU0217 DKK-1 Levels Are Elevated in Patients with Enthesitis Related Arthritis without Sacroiliac Joint Fusion Annals of the Rheumatic Diseases. 75: 266-267. DOI: 10.1136/Annrheumdis-2016-Eular.6050 |
0.273 |
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| 2018 |
Piper CJM, Wilkinson MGL, Deakin CT, Otto GW, Dowle S, Duurland CL, Adams S, Marasco E, Rosser EC, Radziszewska A, Carsetti R, Ioannou Y, Beales PL, Kelberman D, Isenberg DA, et al. CD19CD24CD38 B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α. Frontiers in Immunology. 9: 1372. PMID 29988398 DOI: 10.3389/Fimmu.2018.01372 |
0.272 |
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| 2015 |
Cousins L, Pericleous C, Khamashta M, Bertolaccini ML, Ioannou Y, Giles I, Rahman A. Antibodies to domain I of β-2-glycoprotein I and IgA antiphospholipid antibodies in patients with 'seronegative' antiphospholipid syndrome. Annals of the Rheumatic Diseases. 74: 317-9. PMID 25359383 DOI: 10.1136/Annrheumdis-2014-206483 |
0.272 |
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| 2016 |
D’Souza AN, Pericleous C, Leach O, Alber KF, McDonnell T, Ioannou Y, Giles I, Isenberg DA, Rahman A. 268 Different Patterns of Positivity for IgG Anti-Cardiolipin, Anti-β2-Glycoprotein I and Anti-Domain I Antibodies within the First Year of Disease in 501 Patients with Systemic Lupus Erythematosus: Associations with Different Clinical Outcomes Rheumatology. 55. DOI: 10.1093/Rheumatology/Kew188.010 |
0.27 |
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| 2016 |
Sangodkar J, Tohme R, Kiselar J, Izadmehr S, Hoon D, Mazhar S, Perl A, Wiredja D, Schlatzer D, Yao S, Kastrinsky D, Sharma N, Brautigan D, Chance M, Borczuk A, ... ... Ioannou Y, et al. Abstract 3865: Therapeutic activation of protein phosphatase 2A for the treatment of lung cancer Cancer Research. 76: 3865-3865. DOI: 10.1158/1538-7445.Am2016-3865 |
0.27 |
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| 2002 |
Sultan SM, Ioannou Y, Moss K, Isenberg DA. Outcome in patients with idiopathic inflammatory myositis: morbidity and mortality. Rheumatology. 41: 22-26. PMID 11792875 DOI: 10.1093/Rheumatology/41.1.22 |
0.268 |
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| 2007 |
Lambrianides A, Giles I, Ioannou Y, Mason L, Latchman DS, Manson JJ, Isenberg DA, Rahman A. Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome Arthritis and Rheumatism. 56: 2392-2401. PMID 17599767 DOI: 10.1002/Art.22743 |
0.268 |
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| 2016 |
Davies R, Carrasco R, Foster HE, Baildam EM, Chieng SE, Davidson JE, Ioannou Y, Wedderburn LR, Thomson W, Hyrich KL. Treatment prescribing patterns in patients with juvenile idiopathic arthritis (JIA): Analysis from the UK Childhood Arthritis Prospective Study (CAPS). Seminars in Arthritis and Rheumatism. PMID 27422803 DOI: 10.1016/J.Semarthrit.2016.06.001 |
0.267 |
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| 2015 |
Poulton K, Ripoll VM, Pericleous C, Meroni PL, Gerosa M, Ioannou Y, Rahman A, Giles IP. Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 73: 390-401. PMID 25469631 DOI: 10.1111/Aji.12341 |
0.265 |
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| 2000 |
Sultan SM, Ioannou Y, Isenberg DA. Is there an association of malignancy with systemic lupus erythematosus? An analysis of 276 patients under long‐term review Rheumatology. 39: 1147-1152. PMID 11035137 DOI: 10.1093/Rheumatology/39.10.1147 |
0.265 |
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| 2020 |
Robinson G, Peng J, Radziszewska A, Wincup C, Peckham H, Naja M, Isenberg D, Ioannou Y, Pineda-Torra I, Ciurtin C, Jury E. P36 Using machine learning to identify and stratify patients with juvenile-onset SLE Lupus Science & Medicine. 7. DOI: 10.1136/Lupus-2020-Eurolupus.84 |
0.265 |
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| 2017 |
Fisher C, Eleftheriou D, Sen D, Ioannou Y. OP0056 IL-23P19 is up-regulated in monocyte-derived macrophages from HLA B27 positive patients with enthesitis related arthritis Annals of the Rheumatic Diseases. 76: 74-74. DOI: 10.1136/Annrheumdis-2017-Eular.5004 |
0.265 |
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| 2002 |
Ziegler RJ, Li C, Cherry M, Zhu Y, Hempel D, van Rooijen N, Ioannou YA, Desnick RJ, Goldberg MA, Yew NS, Cheng SH. Correction of the nonlinear dose response improves the viability of adenoviral vectors for gene therapy of Fabry disease. Human Gene Therapy. 13: 935-45. PMID 12031126 DOI: 10.1089/10430340252939041 |
0.264 |
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| 2014 |
Amaral B, Murphy G, Ioannou Y, Isenberg DA. A comparison of the outcome of adolescent and adult-onset systemic lupus erythematosus. Rheumatology (Oxford, England). 53: 1130-5. PMID 24505121 DOI: 10.1093/Rheumatology/Ket488 |
0.263 |
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| 2000 |
Ioannou Y, Isenberg DA. Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy. Arthritis & Rheumatism. 43: 1431-1442. PMID 10902743 DOI: 10.1002/1529-0131(200007)43:7<1431::Aid-Anr3>3.0.Co;2-E |
0.263 |
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| 2018 |
McClinch K, A Avelar R, Callejas D, Izadmehr S, Wiredja D, Perl A, Sangodkar J, Kastrinsky DB, Schlatzer D, Cooper M, Kiselar J, Stachnik A, Yao S, Hoon D, McQuaid D, ... ... Ioannou YA, et al. Small molecule activators of protein phosphatase 2A for the treatment of castration-resistant prostate cancer. Cancer Research. PMID 29358171 DOI: 10.1158/0008-5472.Can-17-0123 |
0.263 |
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| 2008 |
Labonté ED, Camarota LM, Rojas JC, Jandacek RJ, Gilham DE, Davies JP, Ioannou YA, Tso P, Hui DY, Howles PN. Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice American Journal of Physiology - Gastrointestinal and Liver Physiology. 295: G776-G783. PMID 18718999 DOI: 10.1152/Ajpgi.90275.2008 |
0.262 |
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| 2009 |
Giannakopoulos B, Passam F, Ioannou Y, Krilis SA. How we diagnose the antiphospholipid syndrome Blood. 113: 985-994. PMID 18755986 DOI: 10.1182/Blood-2007-12-129627 |
0.262 |
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| 1998 |
Ioannou YA, Zeidner KM, Grace ME, Desnick RJ. Human alpha-galactosidase A: glycosylation site 3 is essential for enzyme solubility. The Biochemical Journal. 332: 789-97. PMID 9620884 DOI: 10.1042/Bj3320789 |
0.262 |
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| 2018 |
Fisher C, Eleftheriou D, Sen D, Ioannou Y. FRI0004 Granulocyte macrophage colony stimulating factor is secreted at higher levels from stimulated monocyte-derived macrophages from patients with enthesitis related arthritis and is significantly enhanced by the unfolded protein response Annals of the Rheumatic Diseases. 77: 549-549. DOI: 10.1136/Annrheumdis-2018-Eular.5457 |
0.262 |
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| 2011 |
Lambrianides A, Turner-Stokes T, Pericleous C, Ehsanullah J, Papadimitraki E, Poulton K, Ioannou Y, Lawrie A, Mackie I, Chen P, Latchman D, Isenberg D, Rahman A, Giles I. Interactions of human monoclonal and polyclonal antiphospholipid antibodies with serine proteases involved in hemostasis. Arthritis and Rheumatism. 63: 3512-21. PMID 21739425 DOI: 10.1002/Art.30525 |
0.262 |
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| 2017 |
Peckham H, Cambridge G, Bourke L, Sen D, Radziszewska A, Leandro M, Ioannou Y. Antibodies to citrullinated peptides in patients with juvenile idiopathic arthritis and rheumatoid arthritis: Shared expression of the inherently autoreactive 9G4 idiotype. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28380667 DOI: 10.1002/Art.40117 |
0.262 |
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| 2002 |
Oishi K, Hofmann S, Diaz GA, Brown T, Manwani D, Ng L, Young R, Vlassara H, Ioannou YA, Forrest D, Gelb BD. Targeted disruption of Slc19a2, the gene encoding the high-affinity thiamin transporter Thtr-1, causes diabetes mellitus, sensorineural deafness and megaloblastosis in mice. Human Molecular Genetics. 11: 2951-60. PMID 12393806 DOI: 10.1093/Hmg/11.23.2951 |
0.262 |
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| 2018 |
Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, Chuang LS, Carmi S, Villaverde N, Li X, Rivas M, Levine AP, Bao X, Labrias PR, Haritunians T, ... ... Ioannou Y, et al. Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. Science Translational Medicine. 10. PMID 29321258 DOI: 10.1126/Scitranslmed.Aai7795 |
0.261 |
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| 2017 |
Hanns L, Suffield L, Josephs F, Chaplin H, Radziszewska A, Carvalho LA, Sen D, Christie D, Ioannou Y. Bspar Oral Abstractso25. The Association Between Psychological Health, Inflammation And Disease Activity For Adolescent Patients With Juvenile Idiopathic Arthritis Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex061.025 |
0.26 |
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| 1998 |
Matsuura F, Ohta M, Ioannou YA, Desnick RJ. Human alpha-galactosidase A: characterization of the N-linked oligosaccharides on the intracellular and secreted glycoforms overexpressed by Chinese hamster ovary cells. Glycobiology. 8: 329-39. PMID 9499380 DOI: 10.1093/Glycob/8.4.329 |
0.26 |
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| 2014 |
McErlane F, Foster HE, Carrasco R, Baildam EM, Chieng ASE, Davidson JD, Ioannou Y, Wedderburn LR, Thomson W, Hyrich K. AB0901 Trends in Paediatric Rheumatology Referral Times and Disease Activity Indices over A Ten-Year Period among Children with Juvenile Idiopathic Arthritis: Results from the Childhood Arthritis Prospective Study (CAPS) Annals of the Rheumatic Diseases. 73: 1098-1099. DOI: 10.1136/Annrheumdis-2014-Eular.3680 |
0.26 |
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| 2015 |
Raimondo MG, Pericleous C, Radziszewska A, Borghi MO, Meroni PL, Giles I, Rahman A, Ioannou Y. OP0084 Oxidation of β2-Glycoprotein I is Strongly Associated with the Presence of Anti-Domain I Antibodies in Patients With Antiphospholipid Syndrome Annals of the Rheumatic Diseases. 74: 100-100. DOI: 10.1136/Annrheumdis-2015-Eular.4222 |
0.26 |
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| 2009 |
Tang W, Ma Y, Jia L, Ioannou YA, Davies JP, Yu L. Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8 Journal of Lipid Research. 50: 293-300. PMID 18796403 DOI: 10.1194/Jlr.M800439-Jlr200 |
0.259 |
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| 2002 |
Moss KE, Ioannou Y, Sultan SM, Haq I, Isenberg DA. Outcome of a cohort of 300 patients with systemic lupus erythematosus attending a dedicated clinic for over two decades Annals of the Rheumatic Diseases. 61: 409-413. PMID 11959764 DOI: 10.1136/Ard.61.5.409 |
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| 2014 |
Lom H, Nistala K, Bending D, Ioannou Y, Bajaj-Elliott M, Wedderburn LR. YIM-P59. Relationships between the Th17 and innate lymphoid cell signature in enthesitis related arthritis Pediatric Rheumatology. 12: 1-2. DOI: 10.1186/1546-0096-12-S1-Y6 |
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| 2016 |
Hanns L, Cordingley L, Galloway J, Norton S, Carvalho LA, Christie D, Sen D, Carrasco R, Rashid A, Foster H, Baildam E, Cheing A, Davidson J, Wedderburn L, Hyrich K, ... ... Ioannou Y, et al. OP0300 Do Depressive Symptoms at Disease Onset Associate with Future Disease Activity for Adolescent Patients with Jia? Results from The Childhood Arthritis Prospective Study (CAPS) Annals of the Rheumatic Diseases. 75: 171-171. DOI: 10.1136/Annrheumdis-2016-Eular.1911 |
0.258 |
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| 1998 |
Osman N, McKenzie IF, Ostenried K, Ioannou YA, Desnick RJ, Sandrin MS. Combined transgenic expression of alpha-galactosidase and alpha1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galalpha(1,3)Gal. Proceedings of the National Academy of Sciences of the United States of America. 94: 14677-82. PMID 9405672 DOI: 10.1073/Pnas.94.26.14677 |
0.258 |
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| 2017 |
Ferreira I, Croca S, Raimondo MG, Matharu M, Miller S, Giles I, Isenberg D, Ioannou Y, Hanly JG, Urowitz MB, Anderson N, Aranow C, Askanase A, Bae SC, Bernatsky S, et al. Nitrated nucleosome levels and neuropsychiatric events in systemic lupus erythematosus; a multi-center retrospective case-control study. Arthritis Research & Therapy. 19: 287. PMID 29273092 DOI: 10.1186/S13075-017-1495-6 |
0.256 |
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| 1997 |
Gotlib RW, Bishop DF, Wang AM, Zeidner KM, Ioannou YA, Adler DA, Disteche CM, Desnick RJ. The entire genomic sequence and cDNA expression of mouse alpha-galactosidase A. Biochemical and Molecular Medicine. 57: 139-48. PMID 8733892 DOI: 10.1006/Bmme.1996.0020 |
0.256 |
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| 2015 |
Artim-Esen B, Pericleous C, Mackie I, Ripoll VM, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I. Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays. Arthritis Research & Therapy. 17: 47. PMID 25890027 DOI: 10.1186/S13075-015-0568-7 |
0.256 |
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| 2018 |
Hendry GJ, Shoop-Worrall SJ, Riskowski JL, Andrews P, Baildam E, Chieng A, Davidson J, Ioannou Y, McErlane F, Wedderburn LR, Hyrich K, Thomson W, Steultjens M. Prevalence and course of lower limb disease activity and walking disability over the first 5 years of juvenile idiopathic arthritis: results from the childhood arthritis prospective study. Rheumatology Advances in Practice. 2: rky039. PMID 30627693 DOI: 10.1093/Rap/Rky039 |
0.256 |
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| 2017 |
Bray T, Fisher C, Sen D, Ioannou Y, Hall-Craggs M. 4. The Natural History of Enthesitis-related Arthritis on Biologic Therapy Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex390.004 |
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| 2015 |
Fisher C, Suffield L, Radziszewska A, Sen D, Ioannou Y. OP4. Enthesitis-related arthritis in adolescence: disease phenotype in a large cohort Rheumatology. 54. DOI: 10.1093/Rheumatology/Keu493 |
0.255 |
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| 1992 |
Ioannou YA, Bishop DF, Desnick RJ. Overexpression of human alpha-galactosidase A results in its intracellular aggregation, crystallization in lysosomes, and selective secretion. The Journal of Cell Biology. 119: 1137-50. PMID 1332979 DOI: 10.1083/Jcb.119.5.1137 |
0.255 |
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| 2012 |
Fisher C, Ioannou Y, Hall-Craggs M, Sen D. Enthesitis Related Arthritis; a New Era of Understanding - Annals of Paediatric Rheumatology. 1: 8-16. DOI: 10.5455/Apr.011520120733 |
0.254 |
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| 2016 |
Bray TJ, Vendhan K, Roberts J, Atkinson D, Punwani S, Sen D, Ioannou Y, Hall-Craggs MA. Association of the apparent diffusion coefficient with maturity in adolescent sacroiliac joints. Journal of Magnetic Resonance Imaging : Jmri. PMID 26898474 DOI: 10.1002/Jmri.25209 |
0.254 |
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| 1999 |
Sultan SM, Ioannou Y, Isenberg DA. A review of gastrointestinal manifestations of systemic lupus erythematosus Rheumatology. 38: 917-932. PMID 10534541 DOI: 10.1093/Rheumatology/38.10.917 |
0.253 |
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| 2010 |
Morgan MD, Burke F, Biela C, Harper L, Gordon C, Young SP, Goulden BS, Turner-Stokes TJ, Pericleous C, Lambrianides A, Bell K, Ioannou Y, Latchman D, Isenberg D, Rahman A, ... ... Ioannou Y, et al. SLE and Antiphospholipid Syndrome [223-231]: 223. Acid Disruption Biacore Analysis of Antibodies Against Rituximab in SLE Patients Rheumatology. 49: i119-i122. DOI: 10.1093/Rheumatology/Keq728 |
0.253 |
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| 2017 |
Lythgoe H, Morgan T, Heaf E, Lloyd O, Al-Abadi E, Armon K, Bailey K, Davidson J, Friswell M, Gardner-Medwin J, Haslam K, Ioannou Y, Leahy A, Leone V, Pilkington C, et al. Evaluation of the ACR and SLICC classification criteria in juvenile-onset systemic lupus erythematosus: a longitudinal analysis. Lupus. 961203317700484. PMID 28361566 DOI: 10.1177/0961203317700484 |
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| 2014 |
Artim-Esen B, Pericleous C, Mackie I, Isenberg D, Rahman A, Ioannou Y, Giles I. 324. Factor-Xa-Reactive Antibodies in Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome Have Differential Effects on Coagulation Assays Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu128.004 |
0.252 |
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| 2000 |
Ioannou YA, Zeidner KM, Gordon RE, Desnick RJ. Fabry disease: preclinical studies demonstrate the effectiveness of alpha-galactosidase A replacement in enzyme-deficient mice. American Journal of Human Genetics. 68: 14-25. PMID 11115376 DOI: 10.1086/316953 |
0.252 |
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| 2018 |
Shoop-Worrall SJ, Verstappen SM, McDonagh JE, Baildam E, Chieng A, Davidson J, Foster H, Ioannou Y, McErlane F, Wedderburn LR, Thomson W, Hyrich KL. Long term outcomes following achievement of clinically inactive disease in juvenile idiopathic arthritis: the importance of definition. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29648683 DOI: 10.1002/Art.40519 |
0.251 |
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| 2014 |
Patil P, Parker RA, Rawcliffe C, Olaleye A, Moore S, Daly N, Sen D, Ioannou Y. Methotrexate-induced nausea and vomiting in adolescent and young adult patients. Clinical Rheumatology. 33: 403-7. PMID 24108504 DOI: 10.1007/S10067-013-2389-X |
0.25 |
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| 2016 |
Pericleous C, Ferreira I, Borghi O, Pregnolato F, McDonnell T, Garza-Garcia A, Driscoll P, Pierangeli S, Isenberg D, Ioannou Y, Giles I, Meroni PL, Rahman A. Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome. Plos One. 11: e0156407. PMID 27253369 DOI: 10.1371/Journal.Pone.0156407 |
0.25 |
|
| 2014 |
Baqai T, Isenberg DA, Ioannou Y. Pathogenesis of neurocognitive and neuropsychiatric manifestations in childhood-onset lupus: an overview Rheumatology Reports. 5: 6. DOI: 10.4081/Rr.2013.E6 |
0.249 |
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| 2016 |
Filippidou N, Krashias G, Pericleous C, Rahman A, Ioannou Y, Giles I, Demetriou C, Anatolitou A, Christodoulou C, Pantzaris M, Lambrianides A. The association between IgG and IgM antibodies against cardiolipin, β2-glycoprotein I and Domain I of β2-glycoprotein I with disease profile in patients with multiple sclerosis. Molecular Immunology. 75: 161-167. PMID 27289032 DOI: 10.1016/J.Molimm.2016.05.022 |
0.249 |
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| 2017 |
Fisher C, Radziszewska A, Sen D, Ioannou Y. 245. Interleukin-23P19 Is Up-Regulated In Monocyte-Derived Macrophages From Human Leucocyte Antigen-B27-Positive Patients With Enthesitis-Related Arthritis In The Presence Of Endoplasmic Reticulum Stress Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex062.247 |
0.248 |
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| 2016 |
Murphy CM, Croca S, Artim-Esen B, Hanns L, Pericleous C, McDonnell T, Ioannou Y, Isenberg D, Rahman A, Giles I. 259 Patients with Systemic Lupus Erythematosus who are Anti-Factor XA IGG Positive are Less Likely to have Atherosclerotic Plaque Rheumatology. 55. DOI: 10.1093/Rheumatology/Kew188.001 |
0.248 |
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| 2014 |
Vendhan K, Sen D, Fisher C, Ioannou Y, Hall-Craggs MA. Inflammatory changes of the lumbar spine in children and adolescents with enthesitis-related arthritis: magnetic resonance imaging findings. Arthritis Care & Research. 66: 40-6. PMID 24127385 DOI: 10.1002/Acr.22201 |
0.246 |
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| 2017 |
Cai RA, Livermore P, Chaplin H, Josephs F, Suffield L, Wilkinson N, Sen D, Eleftheriou D, Tattersall R, Ioannou Y. 289. Developing A Toolkit To Benchmark Young Person–Friendly Services For Patients With Autoimmune Rheumatic Disease Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex062.291 |
0.246 |
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| 2016 |
Shoop SJW, Verstappen SMM, Baildam E, Chieng A, Davidson J, Foster H, Ioannou Y, McErlane F, Wedderburn LR, Thomson W, Hyrich KL. 032 Estimates of Inactive Disease are Strongly Influenced by Outcome Definition in a Prospective Cohort of Patients with Juvenile Idiopathic Arthritis Rheumatology. 55. DOI: 10.1093/Rheumatology/Kew132.004 |
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| 2014 |
Artim-Esen B, Smoktunowicz N, Pericleous C, Ripoll-Nunez V, Chambers R, Mackie I, Isenberg D, Rahman A, Ioannou Y, Giles I. O59. The Cellular Effects of Anti-Factor Xa Antibodies Isolated from Patients with Antiphospholipid Syndrome are Inhibited by Factor Xa Inhibitors, Hydroxychloroquine and Fluvastatin Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu095.005 |
0.245 |
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| 2018 |
Webb K, Peckham H, Radziszewska A, Menon M, Oliveri P, Simpson F, Deakin CT, Lee S, Ciurtin C, Butler G, Wedderburn LR, Ioannou Y. Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration. Frontiers in Immunology. 9: 3167. PMID 30705679 DOI: 10.3389/Fimmu.2018.03167 |
0.245 |
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| 2019 |
Hanns L, Radziszewska A, Suffield L, Josephs F, Chaplin H, Peckham H, Sen D, Christie D, Carvalho LA, Ioannou Y. Anxiety associates with pain and disability but not increased measures of inflammation for adolescent patients with juvenile idiopathic arthritis. Arthritis Care & Research. PMID 31199593 DOI: 10.1002/Acr.24006 |
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| 2010 |
Passam FH, Rahgozar S, Qi M, Raftery MJ, Wong JW, Tanaka K, Ioannou Y, Zhang JY, Gemmell R, Qi JC, Giannakopoulos B, Hughes WE, Hogg PJ, Krilis SA. Beta 2 glycoprotein I is a substrate of thiol oxidoreductases. Blood. 116: 1995-7. PMID 20847215 DOI: 10.1182/Blood-2010-02-271494 |
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| 2007 |
Ioannou Y, Pericleous C, Giles I, Latchman DS, Isenberg DA, Rahman A. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human β2-glycoprotein I: Mutation studies including residues R39 to R43 Arthritis and Rheumatism. 56: 280-290. PMID 17195232 DOI: 10.1002/Art.22306 |
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| 2014 |
Eleftheriou D, Isenberg DA, Wedderburn LR, Ioannou Y. The coming of age of adolescent rheumatology Nature Reviews Rheumatology. 10: 187-193. PMID 24394351 DOI: 10.1038/Nrrheum.2013.202 |
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| 1998 |
Wang AM, Ioannou YA, Zeidner KM, Desnick RJ. Murine alpha-N-acetylgalactosaminidase: isolation and expression of a full-length cDNA and genomic organization: further evidence of an alpha-galactosidase gene family. Molecular Genetics and Metabolism. 65: 165-73. PMID 9787108 DOI: 10.1006/Mgme.1998.2750 |
0.24 |
|
| 2012 |
Baqai T, Ioannou Y. Comparison of juvenile and adult onset systemic lupus erythematosus British Journal of Hospital Medicine. 73: 558-563. PMID 23124285 DOI: 10.12968/Hmed.2012.73.10.558 |
0.239 |
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| 2007 |
Holmes MV, Ioannou Y, Borysiewicz C, Sen D. Juvenile dermatomyositis with Sjögren's syndrome. Clinical Rheumatology. S3-5. PMID 18097712 DOI: 10.1007/S10067-007-0795-7 |
0.239 |
|
| 1999 |
Ioannou Y, Isenberg DA. Immunisation of patients with systemic lupus erythematosus: the current state of play. Lupus. 8: 497-501. PMID 10483025 DOI: 10.1191/096120399678840855 |
0.238 |
|
| 2018 |
Hanns L, Cordingley L, Galloway J, Norton S, Carvalho LA, Christie D, Sen D, Carrasco R, Rashid A, Foster H, Baildam E, Chieng A, Davidson J, Wedderburn LR, Hyrich K, ... ... Ioannou Y, et al. Depressive symptoms, pain and disability for adolescent patients with juvenile idiopathic arthritis: results from the Childhood Arthritis Prospective Study. Rheumatology (Oxford, England). PMID 29697850 DOI: 10.1093/Rheumatology/Key088 |
0.234 |
|
| 2018 |
Wilkinson MGL, Radziszewska A, Ioannou Y, Jury EC, Manson J, Isenberg D. 254 Th17 cells are increased in adult dermatomyositis: a developing immune signature for the idiopathic inflammatory myopathies Rheumatology. 57. DOI: 10.1093/Rheumatology/Key075.478 |
0.234 |
|
| 2019 |
Cai RA, Chaplin H, Livermore P, Lee M, Sen D, Wedderburn LR, Wilkinson N, Jeffery R, Kempa A, Norton I, Tattersall R, Ioannou Y, Eleftheriou D. Development of a benchmarking toolkit for adolescent and young adult rheumatology services (BeTAR). Pediatric Rheumatology Online Journal. 17: 23. PMID 31113443 DOI: 10.1186/S12969-019-0323-8 |
0.233 |
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| 2014 |
Bourke L, McCormick J, Ripoll VM, Pericleous C, Stephanou A, Ioannou Y. Purified IgG from patients with juvenile and adult onset sle enhances apoptosis in neonatal rat cardiomyocytes exposed to myocardial I/R injury Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu269.042 |
0.232 |
|
| 2014 |
Bourke L, McCormick J, Ripoll VM, Pericleous C, Radziszewska A, Stephanou A, Ioannou Y. 329. Purified IGG from Patients with Systemic Lupus Erythematosus Enhances Apoptosis in Neonatal Rat Cardiomyocytes Exposed to Simulated Myocardial Ischaemic Reperfusion Injury Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu128.009 |
0.23 |
|
| 2016 |
McErlane F, Foster HE, Carrasco R, Baildam EM, Chieng SE, Davidson JE, Ioannou Y, Wedderburn LR, Thomson W, Hyrich KL. Trends in paediatric rheumatology referral times and disease activity indices over a ten-year period among children and young people with Juvenile Idiopathic Arthritis: results from the childhood arthritis prospective Study. Rheumatology (Oxford, England). PMID 27016664 DOI: 10.1093/Rheumatology/Kew021 |
0.23 |
|
| 2014 |
Chiewchengchol D, Murphy R, Morgan T, Edwards SW, Leone V, Friswell M, Pilkington C, Tullus K, Rangaraj S, McDonagh JE, Gardner-Medwin J, Wilkinson N, Riley P, Tizard J, Armon K, ... ... Ioannou Y, et al. Mucocutaneous manifestations in a UK national cohort of juvenile-onset systemic lupus erythematosus patients. Rheumatology (Oxford, England). 53: 1504-12. PMID 24692572 DOI: 10.1093/Rheumatology/Keu137 |
0.229 |
|
| 2010 |
Passam FH, Rahgozar S, Qi M, Raftery MJ, Wong JW, Tanaka K, Ioannou Y, Zhang JY, Gemmell R, Qi JC, Giannakopoulos B, Hughes WE, Hogg PJ, Krilis SA. Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1. Journal of Thrombosis and Haemostasis : Jth. 8: 1754-62. PMID 20979592 DOI: 10.1111/J.1538-7836.2010.03944.X |
0.228 |
|
| 2015 |
Hanns L, Suffield L, Radziszewska A, Sen D, Christie D, Ioannou Y. 273. In Adolescent Patients with Juvenile Idiopathic Arthritis, Anxiety and Mood Predicts Function Whereas Life Event Stressors in the Older Adolescent Predicts Inflammation Rheumatology. 54. DOI: 10.1093/Rheumatology/Kev090.038 |
0.227 |
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| 2019 |
Shoop-Worrall SJW, Hyrich KL, Verstappen SM, Sergeant JC, Baildam E, Chieng A, Davidson J, Foster H, Ioannou Y, McErlane F, Wedderburn LR, Thomson W, McDonagh JE. Comparing Proxy, Adolescent and Adult Assessments of Functional Ability in Adolescents with Juvenile Idiopathic Arthritis. Arthritis Care & Research. PMID 30875458 DOI: 10.1002/Acr.23877 |
0.226 |
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| 2018 |
Fisher C, Eleftheriou D, Sen D, Ioannou Y. OP0097 Stimulated monocyte-derived macrophages from patients with enthesitis related arthritis secrete higher levels of il23 and lower levels of interferon gamma compared to healthy controls Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2018-Eular.5377 |
0.226 |
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| 2015 |
Thornton CC, Ambrose N, Ioannou Y. Ofatumumab: a novel treatment for severe systemic lupus erythematosus. Rheumatology (Oxford, England). 54: 559-60. PMID 25539826 DOI: 10.1093/Rheumatology/Keu475 |
0.225 |
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| 2017 |
McDonnell TCR, Willis R, Pericleous C, Giles I, Romay-Penabad Z, Papalardo E, Ioannou Y, Rahman A. 239. Pegylated Domain I Of Beta-2-Glycoprotein I Prevents Thrombosis In A Mouse Model Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex062.241 |
0.225 |
|
| 2014 |
La Hausse de Lalouvière L, Ioannou Y, Fitzgerald M. Neural mechanisms underlying the pain of juvenile idiopathic arthritis. Nature Reviews. Rheumatology. 10: 205-11. PMID 24492386 DOI: 10.1038/Nrrheum.2014.4 |
0.224 |
|
| 2000 |
Ohta M, Ohnishi T, Ioannou YA, Hodgson ME, Matsuura F, Desnick RJ. Human alpha-N-acetylgalactosaminidase: site occupancy and structure of N-linked oligosaccharides. Glycobiology. 10: 251-61. PMID 10704524 DOI: 10.1093/Glycob/10.3.251 |
0.224 |
|
| 2012 |
Campbell R, Hofmann D, Hatch S, Gordon P, Lempp H, Das L, Blumbergs P, Limaye V, Vermaak E, McHugh N, Edwards MH, Jameson K, Sayer AA, Dennison E, Cooper C, ... ... Ioannou Y, ... ... Ioannou Y, ... ... Ioannou Y, et al. Muscle disorders * 111. The impact of fatigue in patients with idiopathic inflammatory myopathy: a mixed method study Rheumatology. 51: iii93-iii139. DOI: 10.1093/Rheumatology/Kes109 |
0.224 |
|
| 2015 |
Bourke L, McCormick J, Taylor V, Pericleous C, Blanchet B, Costedoat-Chalumeau N, Stuckey D, Lythgoe MF, Stephanou A, Ioannou Y. Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation. Plos One. 10: e0143771. PMID 26636577 DOI: 10.1371/Journal.Pone.0143771 |
0.221 |
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| 2014 |
Carrasco R, Holt S, Foster H, Wedderburn L, Cheing A, Davidson J, Ioannou Y, Hyrich K, Thomson W, Baildam E. Intra-articular corticosteroid injections in juvenile idiopathic arthritis Pediatric Rheumatology. 12: 12. DOI: 10.1186/1546-0096-12-S1-P12 |
0.221 |
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| 2015 |
Bourke L, McCormick J, Ripoll VM, Pericleous C, Stephanou A, Ioannou Y. O41. Antiphospholipid Antibodies Enhance Cardiomyocyte Apoptosis in A Simulated in Vitro Cardiac Ischaemia/Reperfusion Injury Model: A Process Dependent on the Pro-Apoptotic Kinase P38 Mapk Rheumatology. 54. DOI: 10.1093/Rheumatology/Kev085.005 |
0.221 |
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| 2015 |
Bray TP, Vendhan K, Fisher C, Sen D, Ioannou Y, Hall-Craggs MA. Low back pain in adolescent inflammatory arthritis can be due to lumbar spine apophyseal joint inflammation and this requires contrast enhancement for adequate assessment. Comment on the article by Weiss et al. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26474090 DOI: 10.1002/Art.39452 |
0.221 |
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| 2017 |
Radziszewska A, Webb K, Peckham H, Ioannou Y. THU0484 Ro60 expression decreases with age in peripheral blood mononuclear cells of children and adolescents and correlates with tlr7 stimulation in pdcs of prepubertal children Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2017-Eular.5073 |
0.22 |
|
| 2014 |
Fisher C, Suffield L, Sen D, Ioannou Y. High body mass index: cause or consequence of chronic pain syndromes in adolescent patients? Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu269.047 |
0.219 |
|
| 2016 |
J P Bray T, Vendhan K, Ambrose N, Atkinson D, Punwani S, Fisher C, Sen D, Ioannou Y, Hall-Craggs MA. Diffusion-weighted imaging is a sensitive biomarker of response to biologic therapy in enthesitis-related arthritis. Rheumatology (Oxford, England). PMID 27994095 DOI: 10.1093/Rheumatology/Kew429 |
0.218 |
|
| 2017 |
McErlane F, Carrasco R, Kearsley-Fleet L, Baildam EM, Wedderburn LR, Foster HE, Ioannou Y, Chieng SEA, Davidson JE, Thomson W, Hyrich KL. Growth patterns in early juvenile idiopathic arthritis: Results from the Childhood Arthritis Prospective Study (CAPS). Seminars in Arthritis and Rheumatism. PMID 29217290 DOI: 10.1016/J.Semarthrit.2017.11.002 |
0.217 |
|
| 2017 |
Hanns L, Suffield L, Josephs F, Chaplin H, Radziszewska A, Carvalho LA, Sen D, Christie D, Ioannou Y. 21. Adolescents with juvenile idiopathic arthritis experience lower levels of life event stress and trait anxiety than healthy adolescents Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex390.021 |
0.216 |
|
| 2012 |
McErlane F, Beresford MW, Baildam EM, Thomson W, Hyrich K, Chieng A, Davidson J, Foster HE, Gardner-Medwin J, Lunt M, Wedderburn L, Nikiphorou E, Carpenter L, Kiely P, Walsh D, ... ... Ioannou Y, et al. Oral abstracts 3: RA Treatment and outcomesO13. Validation of jadas in all subtypes of juvenile idiopathic arthritis in a clinical setting Rheumatology. 51. DOI: 10.1093/Rheumatology/Kes119 |
0.216 |
|
| 2017 |
Wincup C, Ioannou Y, Richards T, Josephs F, Suffield L, Rahman A. THU0265 Identifying the links between iron deficiency and fatigue in adolescents and young adults with systemic lupus erythematosus Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2017-Eular.2440 |
0.216 |
|
| 2018 |
Chaplin H, Barnett R, Ioannou Y, Sen D, Lempp H, Cai RA, Norton S. 299 The impact of juvenile idiopathic arthritis on adolescents and young adults: a qualitative study Rheumatology. 57. DOI: 10.1093/Rheumatology/Key075.523 |
0.215 |
|
| 1994 |
Murali R, Ioannou YA, Desnick RJ, Burnett RM. Crystallization and preliminary X-ray analysis of human α-galactosidase A complex Journal of Molecular Biology. 239: 578-580. PMID 8006970 DOI: 10.1006/Jmbi.1994.1397 |
0.215 |
|
| 2016 |
Bray TJ, Amies T, Vendhan K, Humphries P, Sen D, Ioannou Y, Hall-Craggs MA. Discordant Inflammatory Change in the Apophyseal and Sacroiliac Joints: Serial Observations in Enthesitis-related Arthritis. The British Journal of Radiology. 20160353. PMID 27376529 DOI: 10.1259/Bjr.20160353 |
0.215 |
|
| 2017 |
Hanns L, Suffield L, Josephs F, Chaplin H, Radziszewska A, Carvalho LA, Sen D, Christie D, Ioannou Y. 296. Adolescents With Juvenile Idiopathic Arthritis Experience Lower Levels Of Life Event Stress Than Healthy Adolescents Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex062.298 |
0.215 |
|
| 2005 |
Ioannou Y, Bowman SJ, Rahman A, Giles IP. Review of presentations at the 6th European Lupus Meeting 3-5 March 2005. Lupus. 14: 467-478. PMID 16038111 DOI: 10.1191/0961203305Lu2172Xx |
0.213 |
|
| 2018 |
Chaplin H, Ioannou Y, Sen D, Josephs F, Hibberd Y, Norton S. O25 Exploring a biopsychosocial approach to pain in adolescents and young adults with juvenile idiopathic arthritis (young investigator award winner 2018) Rheumatology. 57. DOI: 10.1093/Rheumatology/Key075.207 |
0.211 |
|
| 2018 |
Chaplin H, Ioannou Y, Sen D, Lempp H, Norton S. OP0101 Exploring pain and the impact of jia on adolescents and young adults: a mixed-methods study Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2018-Eular.2599 |
0.205 |
|
| 2017 |
Rashid A, Cordingley L, Carrasco R, Foster HE, Baildam EM, Chieng A, Davidson JE, Wedderburn LR, Ioannou Y, McErlane F, Verstappen SMM, Hyrich KL, Thomson W. Patterns of pain over time among children with juvenile idiopathic arthritis. Archives of Disease in Childhood. PMID 29175824 DOI: 10.1136/Archdischild-2017-313337 |
0.203 |
|
| 2014 |
Daly N, Dunnage J, Howard P, Ioannou Y. A dedicated young persons lupus support group Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu269.026 |
0.202 |
|
| 2000 |
Ioannou YA. A Frozen Database Science. 288: 1191a-1191. DOI: 10.1126/Science.288.5469.1191A |
0.197 |
|
| 2005 |
Rahman A, Bowman SJ, Giles IP, Ioannou Y, Isenberg DA. Annus mirabilis—a guide to the 6th European Lupus Meeting, 3–5 March 2005 Rheumatology. 44: 962-964. PMID 15927996 DOI: 10.1093/Rheumatology/Keh702 |
0.195 |
|
| 2014 |
Bourke L, McCormick J, Franklin J, Stephanou A, Ioannou Y. O45. Hydroxychloroquine is Cardioprotective in Neonatal RAT Cardiomyocytes Exposed to Simulated Myocardial Ischaemic/Reperfusion Injury: An Effect Mediated Through ERK Phosphorylation Rheumatology. 53. DOI: 10.1093/Rheumatology/Keu093.003 |
0.195 |
|
| 2018 |
Bray TJP, Bainbridge A, Punwani S, Ioannou Y, Hall-Craggs MA. Simultaneous Quantification of Bone Edema/Adiposity and Structure in Inflamed Bone Using Chemical Shift-Encoded MRI in Spondyloarthritis. Magnetic Resonance in Medicine. 79: 1031-1042. PMID 28589660 DOI: 10.1002/Mrm.26729 |
0.193 |
|
| 2017 |
Papadopoulou C, Hong Y, Krol P, Ioannou Y, Pilkington C, Chaplin H, Simou S, Charakida M, Wedderburn L, Brogan P, Eleftheriou D. 7. The vasculopathy of JDM; evidence of persistent endothelial injury, hypercoagulability, subclinical inflammation and increased arterial stiffness Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex390.007 |
0.191 |
|
| 2017 |
Glackin Y, Chaplin H, Simou S, Almeida B, Papadopoulou C, Barwick L, Ioannou Y, Wedderburn LR, Pilkington C. 28. A pilot project to assess the impact of a Family Day – Helping young people and their families to meet and share their experiences of living with Juvenile Dermatomyositis Rheumatology. 56. DOI: 10.1093/Rheumatology/Kex390.028 |
0.19 |
|
| 2000 |
Ioannou YA. SOFTWARE: New Primer Predictor Science. 290: 1319b-1319. DOI: 10.1126/Science.290.5495.1319B |
0.189 |
|
| 2017 |
Benedetti FD, Anton J, Gattorno M, Lachmann H, Kone-Paut I, Ozen S, Frenkel J, Simon A, Zeft A, Ben-Chetrit E, Hoffman HM, Joubert Y, Lheritier K, Speziale A, Guido J, ... ... Ioannou Y, et al. Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two: Genoa, Italy. 28 September – 01 October 2016. Pediatric Rheumatology. 15. DOI: 10.1186/S12969-017-0142-8 |
0.183 |
|
| 2000 |
Ioannou YA. Gene therapy for lysosomal storage disorders with neuropathology. Journal of the American Society of Nephrology : Jasn. 11: 1542-1547. PMID 10906169 DOI: 10.1681/ASN.V1181542 |
0.145 |
|
| 2020 |
Robinson GA, Peng J, Dönnes P, Coelewij L, Naja M, Radziszewska A, Wincup C, Peckham H, Isenberg DA, Ioannou Y, Pineda-Torra I, Ciurtin C, Jury EC. Disease-associated and patient-specific immune cell signatures in juvenile-onset systemic lupus erythematosus: patient stratification using a machine-learning approach. The Lancet Rheumatology. 2: e485-e496. PMID 32818204 DOI: 10.1016/S2665-9913(20)30168-5 |
0.136 |
|
| 2020 |
Barturen G, Babaei S, Català-Moll F, Martínez-Bueno M, Makowska Z, Martorell-Marugán J, Carmona-Sáez P, Toro-Domínguez D, Carnero-Montoro E, Teruel M, Kerick M, Acosta-Herrera M, Le Lann L, Jamin C, Rodríguez-Ubreva J, ... ... Ioannou Y, et al. Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases. Arthritis & Rheumatology (Hoboken, N.J.). PMID 33497037 DOI: 10.1002/art.41610 |
0.13 |
|
| 2011 |
Seested T, Appa RS, Christensen EI, Ioannou YA, Krogh TN, Karpf DM, Nielsen HM. In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver Thrombosis Research. 127: 356-362. PMID 21262526 DOI: 10.1016/j.thromres.2010.12.016 |
0.114 |
|
| 2021 |
Robinson GA, Waddington KE, Coelewij L, Peng J, Naja M, Wincup C, Radziszewska A, Peckham H, Isenberg DA, Ioannou Y, Ciurtin C, Pineda-Torra I, Jury EC. Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE. Ebiomedicine. 103243. PMID 33640328 DOI: 10.1016/j.ebiom.2021.103243 |
0.103 |
|
| 2023 |
Ioannou Y, Beukelman T, Murray M, Erkan D. Incidence of Antiphospholipid Syndrome: Is Estimation Currently Possible? European Journal of Rheumatology. 10: 39-44. PMID 36880810 DOI: 10.5152/eurjrheum.2023.22012 |
0.093 |
|
| 2006 |
Skordis N, Michaelidou M, Savva SC, Ioannou Y, Rousounides A, Kleanthous M, Skordos G, Christou S. The impact of genotype on endocrine complications in thalassaemia major. European Journal of Haematology. 77: 150-6. PMID 16800840 DOI: 10.1111/j.1600-0609.2006.00681.x |
0.078 |
|
| 2005 |
Birns J, Ioannou Y, Shipley ME. An unusual case of weight loss in a patient with refractory rheumatoid arthritis. Age and Ageing. 34: 305-6. PMID 15863419 DOI: 10.1093/ageing/afi079 |
0.049 |
|
| 2000 |
Ioannou YA. SOFTWARE: Sequence Analysis Science. 289: 412a-412. DOI: 10.1126/science.289.5478.412a |
0.019 |
|
| 2015 |
Williams N, Ioannou Y, Stewart C, Gulati P, Singh S. An innovative interactive medical student induction programme in paediatrics. Medical Teacher. 37: 200-1. PMID 25052020 DOI: 10.3109/0142159X.2014.940872 |
0.015 |
|
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