Louis M. Staudt - Publications

Affiliations: 
The George Washington University, Washington, DC, United States 
Area:
Oncology, Cell Biology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Grande BM, Gerhard DS, Jiang A, Griner NB, Abramson JS, Alexander TB, Allen H, Ayers LW, Bethony JM, Bhatia K, Bowen J, Casper C, Choi JK, Culibrk L, Davidsen TM, ... ... Staudt LM, et al. Genome-wide discovery of somatic coding and non-coding mutations in pediatric endemic and sporadic Burkitt lymphoma. Blood. PMID 30617194 DOI: 10.1182/blood-2018-09-871418  0.52
2018 Dadashian EL, McAuley EM, Liu D, Shaffer AL, Young RM, Iyer JR, Kruhlak MJ, Staudt LM, Wiestner A, Herman SEM. TLR signaling is activated in lymph-node resident CLL cells and is only partially inhibited by ibrutinib. Cancer Research. PMID 30498085 DOI: 10.1158/0008-5472.CAN-18-0781  0.32
2018 Nakagawa M, Shaffer AL, Ceribelli M, Zhang M, Wright G, Huang DW, Xiao W, Powell J, Petrus MN, Yang Y, Phelan JD, Kohlhammer H, Dubois SP, Yoo HM, Bachy E, ... ... Staudt LM, et al. Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma. Cancer Cell. PMID 30057145 DOI: 10.1016/j.ccell.2018.06.014  0.32
2018 Phelan JD, Young RM, Webster DE, Roulland S, Wright GW, Kasbekar M, Shaffer AL, Ceribelli M, Wang JQ, Schmitz R, Nakagawa M, Bachy E, Huang DW, Ji Y, Chen L, ... ... Staudt LM, et al. A multiprotein supercomplex controlling oncogenic signalling in lymphoma. Nature. PMID 29925955 DOI: 10.1038/s41586-018-0290-0  0.32
2018 Schmitz R, Wright GW, Huang DW, Johnson CA, Phelan JD, Wang JQ, Roulland S, Kasbekar M, Young RM, Shaffer AL, Hodson DJ, Xiao W, Yu X, Yang Y, Zhao H, ... ... Staudt LM, et al. Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma. The New England Journal of Medicine. 378: 1396-1407. PMID 29641966 DOI: 10.1056/NEJMoa1801445  0.32
2016 Ceribelli M, Hou ZE, Kelly PN, Huang DW, Wright G, Ganapathi K, Evbuomwan MO, Pittaluga S, Shaffer AL, Marcucci G, Forman SJ, Xiao W, Guha R, Zhang X, Ferrer M, ... ... Staudt LM, et al. A Druggable TCF4- and BRD4-Dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm. Cancer Cell. 30: 764-778. PMID 27846392 DOI: 10.1016/j.ccell.2016.10.002  0.32
2016 Rui L, Drennan AC, Ceribelli M, Zhu F, Wright GW, Huang DW, Xiao W, Li Y, Grindle KM, Lu L, Hodson DJ, Shaffer AL, Zhao H, Xu W, Yang Y, ... Staudt LM, et al. Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799566 DOI: 10.1073/pnas.1610970113  0.32
2016 Yang Y, Kelly P, Shaffer AL, Schmitz R, Yoo HM, Liu X, Huang da W, Webster D, Young RM, Nakagawa M, Ceribelli M, Wright GW, Yang Y, Zhao H, Yu X, ... ... Staudt LM, et al. Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma. Cancer Cell. 29: 494-507. PMID 27070702 DOI: 10.1016/j.ccell.2016.03.006  0.32
2016 Hodson DJ, Shaffer AL, Xiao W, Wright GW, Schmitz R, Phelan JD, Yang Y, Webster DE, Rui L, Kohlhammer H, Nakagawa M, Waldmann TA, Staudt LM. Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2. Proceedings of the National Academy of Sciences of the United States of America. PMID 26993806 DOI: 10.1073/pnas.1600557113  0.32
2016 Dekker JD, Park D, Shaffer AL, Kohlhammer H, Deng W, Lee BK, Ippolito GC, Georgiou G, Iyer VR, Staudt LM, Tucker HO. Subtype-specific addiction of the activated B-cell subset of diffuse large B-cell lymphoma to FOXP1. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787899 DOI: 10.1073/pnas.1524677113  0.32
2015 Kelly PN, Romero DL, Yang Y, Shaffer AL, Chaudhary D, Robinson S, Miao W, Rui L, Westlin WF, Kapeller R, Staudt LM. Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy. The Journal of Experimental Medicine. PMID 26621451 DOI: 10.1084/jem.20151074  0.32
2015 Young RM, Wu T, Schmitz R, Dawood M, Xiao W, Phelan JD, Xu W, Menard L, Meffre E, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, ... ... Staudt LM, et al. Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens. Proceedings of the National Academy of Sciences of the United States of America. 112: 13447-54. PMID 26483459 DOI: 10.1073/pnas.1514944112  0.32
2015 Kendrick S, Tus K, Wright G, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Braziel RM, Ott G, Delabie J, Cook JR, Weisenburger DD, Greiner TC, Fu K, ... Staudt LM, et al. Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status. Leukemia & Lymphoma. 1-4. PMID 26437080 DOI: 10.3109/10428194.2015.1072767  0.32
2015 Hathcock KS, Padilla-Nash HM, Camps J, Shin DM, Triner D, Shaffer AL, Maul RW, Steinberg SM, Gearhart PJ, Staudt LM, Morse HC, Ried T, Hodes RJ. ATM deficiency in absence of T cells promotes development of NF-kB-dependent murine B cell lymphomas that resemble human ABC DLBCL. Blood. PMID 26400962 DOI: 10.1182/blood-2015-06-654749  0.32
2015 Wang C, McKeithan TW, Gong Q, Zhang W, Bouska A, Rosenwald A, Gascoyne RD, Wu X, Wang J, Muhammad Z, Jiang B, Rohr J, Cannon A, Steidl C, Fu K, ... ... Staudt LM, et al. IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma. Blood. PMID 26268241 DOI: 10.1182/blood-2015-05-644591  0.32
2015 Scott DW, Mottok A, Ennishi D, Wright GW, Farinha P, Ben-Neriah S, Kridel R, Barry GS, Hother C, Abrisqueta P, Boyle M, Meissner B, Telenius A, Savage KJ, Sehn LH, ... ... Staudt LM, et al. Prognostic Significance of Diffuse Large B-Cell Lymphoma Cell of Origin Determined by Digital Gene Expression in Formalin-Fixed Paraffin-Embedded Tissue Biopsies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 2848-56. PMID 26240231 DOI: 10.1200/JCO.2014.60.2383  0.32
2015 Wilson WH, Young RM, Schmitz R, Yang Y, Pittaluga S, Wright G, Lih CJ, Williams PM, Shaffer AL, Gerecitano J, de Vos S, Goy A, Kenkre VP, Barr PM, Blum KA, ... ... Staudt LM, et al. Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma. Nature Medicine. PMID 26193343 DOI: 10.1038/nm.3884  0.32
2015 Yuan J, Wright G, Rosenwald A, Steidl C, Gascoyne RD, Connors JM, Mottok A, Weisenburger DD, Greiner TC, Fu K, Smith L, Rimsza LM, Jaffe ES, Campo E, Martinez A, ... ... Staudt LM, et al. Identification of Primary Mediastinal Large B-cell Lymphoma at Nonmediastinal Sites by Gene Expression Profiling. The American Journal of Surgical Pathology. PMID 26135560 DOI: 10.1097/PAS.0000000000000473  0.32
2015 Roschewski M, Dunleavy K, Pittaluga S, Moorhead M, Pepin F, Kong K, Shovlin M, Jaffe ES, Staudt LM, Lai C, Steinberg SM, Chen CC, Zheng J, Willis TD, Faham M, et al. Circulating tumour DNA and CT monitoring in patients with untreated diffuse large B-cell lymphoma: a correlative biomarker study. The Lancet. Oncology. 16: 541-9. PMID 25842160 DOI: 10.1016/S1470-2045(15)70106-3  0.32
2015 Weinstock DM, Dalla-Favera R, Gascoyne RD, Leonard JP, Levy R, Lossos IS, Melnick AM, Nowakowski GS, Press OW, Savage KJ, Shipp MA, Staudt LM. A roadmap for discovery and translation in lymphoma. Blood. 125: 2175-7. PMID 25814490 DOI: 10.1182/blood-2015-01-623777  0.32
2015 Young RM, Shaffer AL, Phelan JD, Staudt LM. B-cell receptor signaling in diffuse large B-cell lymphoma. Seminars in Hematology. 52: 77-85. PMID 25805587 DOI: 10.1053/j.seminhematol.2015.01.008  0.32
2015 Iqbal J, Shen Y, Huang X, Liu Y, Wake L, Liu C, Deffenbacher K, Lachel CM, Wang C, Rohr J, Guo S, Smith LM, Wright G, Bhagavathi S, Dybkaer K, ... ... Staudt LM, et al. Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphoma. Blood. 125: 1137-45. PMID 25498913 DOI: 10.1182/blood-2014-04-566778  0.32
2014 Nakagawa M, Schmitz R, Xiao W, Goldman CK, Xu W, Yang Y, Yu X, Waldmann TA, Staudt LM. Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma. The Journal of Experimental Medicine. 211: 2497-505. PMID 25488980 DOI: 10.1084/jem.20140987  0.32
2014 Muppidi JR, Schmitz R, Green JA, Xiao W, Larsen AB, Braun SE, An J, Xu Y, Rosenwald A, Ott G, Gascoyne RD, Rimsza LM, Campo E, Jaffe ES, Delabie J, ... ... Staudt LM, et al. Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma. Nature. 516: 254-8. PMID 25274307 DOI: 10.1038/nature13765  0.32
2014 Kendrick SL, Redd L, Muranyi A, Henricksen LA, Stanislaw S, Smith LM, Perry AM, Fu K, Weisenburger DD, Rosenwald A, Ott G, Gascoyne RD, Jaffe ES, Campo E, Delabie J, ... ... Staudt LM, et al. BCL2 antibodies targeted at different epitopes detect varying levels of protein expression and correlate with frequent gene amplification in diffuse large B-cell lymphoma. Human Pathology. 45: 2144-53. PMID 25090918 DOI: 10.1016/j.humpath.2014.06.005  0.32
2014 Ceribelli M, Kelly PN, Shaffer AL, Wright GW, Xiao W, Yang Y, Mathews Griner LA, Guha R, Shinn P, Keller JM, Liu D, Patel PR, Ferrer M, Joshi S, Nerle S, ... ... Staudt LM, et al. Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 111: 11365-70. PMID 25049379 DOI: 10.1073/pnas.1411701111  0.32
2014 Wilson WH, Pittaluga S, Nicolae A, Camphausen K, Shovlin M, Steinberg SM, Roschewski M, Staudt LM, Jaffe ES, Dunleavy K. A prospective study of mediastinal gray-zone lymphoma. Blood. 124: 1563-9. PMID 25024303 DOI: 10.1182/blood-2014-03-564906  0.32
2014 Ghosh HS, Ceribelli M, Matos I, Lazarovici A, Bussemaker HJ, Lasorella A, Hiebert SW, Liu K, Staudt LM, Reizis B. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. The Journal of Experimental Medicine. 211: 1623-35. PMID 24980046 DOI: 10.1084/jem.20132121  0.32
2014 Iqbal J, Wright G, Wang C, Rosenwald A, Gascoyne RD, Weisenburger DD, Greiner TC, Smith L, Guo S, Wilcox RA, Teh BT, Lim ST, Tan SY, Rimsza LM, Jaffe ES, ... ... Staudt LM, et al. Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma. Blood. 123: 2915-23. PMID 24632715 DOI: 10.1182/blood-2013-11-536359  0.32
2014 Ippolito GC, Dekker JD, Wang YH, Lee BK, Shaffer AL, Lin J, Wall JK, Lee BS, Staudt LM, Liu YJ, Iyer VR, Tucker HO. Dendritic cell fate is determined by BCL11A. Proceedings of the National Academy of Sciences of the United States of America. 111: E998-1006. PMID 24591644 DOI: 10.1073/pnas.1319228111  0.32
2014 Yang Y, Schmitz R, Mitala J, Whiting A, Xiao W, Ceribelli M, Wright GW, Zhao H, Yang Y, Xu W, Rosenwald A, Ott G, Gascoyne RD, Connors JM, Rimsza LM, ... ... Staudt LM, et al. Essential role of the linear ubiquitin chain assembly complex in lymphoma revealed by rare germline polymorphisms. Cancer Discovery. 4: 480-93. PMID 24491438 DOI: 10.1158/2159-8290.CD-13-0915  0.32
2014 Mathews Griner LA, Guha R, Shinn P, Young RM, Keller JM, Liu D, Goldlust IS, Yasgar A, McKnight C, Boxer MB, Duveau DY, Jiang JK, Michael S, Mierzwa T, Huang W, ... ... Staudt LM, et al. High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 2349-54. PMID 24469833 DOI: 10.1073/pnas.1311846111  0.32
2014 Scott DW, Wright GW, Williams PM, Lih CJ, Walsh W, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Smeland EB, Mottok A, Braziel RM, Ott G, Delabie J, ... ... Staudt LM, et al. Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue. Blood. 123: 1214-7. PMID 24398326 DOI: 10.1182/blood-2013-11-536433  0.32
2014 Bouska A, McKeithan TW, Deffenbacher KE, Lachel C, Wright GW, Iqbal J, Smith LM, Zhang W, Kucuk C, Rinaldi A, Bertoni F, Fitzgibbon J, Fu K, Weisenburger DD, Greiner TC, ... ... Staudt LM, et al. Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma. Blood. 123: 1681-90. PMID 24037725 DOI: 10.1182/blood-2013-05-500595  0.32
2014 Manasanch EE, Braylan R, Stetler-Stevenson M, Yuan C, Gounden V, Korde N, Tageja N, Bhutani M, Calvo K, Maric I, Roschewski M, Staudt LM, Landgren O. Lack of MYD88 L265P in non-immunoglobulin M lymphoplasmacytic lymphoma Leukemia and Lymphoma. 55: 1402-1403. PMID 23915224 DOI: 10.3109/10428194.2013.831091  0.32
2013 Mathews LA, Keller JM, McKnight C, Michael S, Shinn P, Liu D, Staudt LM, Thomas CJ, Ferrer M. Multiplexing high-content flow (HCF) and quantitative high-throughput screening (qHTS) to identify compounds capable of decreasing cell viability, activating caspase 3/7, expressing annexin V, and changing mitochondrial membrane integrity. Current Protocols in Chemical Biology. 5: 195-212. PMID 24391083 DOI: 10.1002/9780470559277.ch130060  0.32
2013 Huang X, Meng B, Iqbal J, Ding BB, Perry AM, Cao W, Smith LM, Bi C, Jiang C, Greiner TC, Weisenburger DD, Rimsza L, Rosenwald A, Ott G, Delabie J, ... ... Staudt LM, et al. Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 4520-8. PMID 24220563 DOI: 10.1200/JCO.2012.45.6004  0.32
2013 Bödör C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S, Wang J, Lee AM, Clear A, Montoto S, Matthews J, Iqbal S, Rajnai H, ... ... Staudt LM, et al. EZH2 mutations are frequent and represent an early event in follicular lymphoma. Blood. 122: 3165-8. PMID 24052547 DOI: 10.1182/blood-2013-04-496893  0.32
2013 Enjuanes A, Albero R, Clot G, Navarro A, Beà S, Pinyol M, Martín-Subero JI, Klapper W, Staudt LM, Jaffe ES, Rimsza L, Braziel RM, Delabie J, Cook JR, Tubbs RR, et al. Genome-wide methylation analyses identify a subset of mantle cell lymphoma with a high number of methylated CpGs and aggressive clinicopathological features International Journal of Cancer. 133: 2852-2863. PMID 23754783 DOI: 10.1002/ijc.28321  0.32
2013 Lamy L, Ngo VN, Emre NC, Shaffer AL, Yang Y, Tian E, Nair V, Kruhlak MJ, Zingone A, Landgren O, Staudt LM. Control of autophagic cell death by caspase-10 in multiple myeloma. Cancer Cell. 23: 435-49. PMID 23541952 DOI: 10.1016/j.ccr.2013.02.017  0.32
2013 Sanda T, Tyner JW, Gutierrez A, Ngo VN, Glover J, Chang BH, Yost A, Ma W, Fleischman AG, Zhou W, Yang Y, Kleppe M, Ahn Y, Tatarek J, Kelliher MA, ... ... Staudt LM, et al. TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia. Cancer Discovery. 3: 564-77. PMID 23471820 DOI: 10.1158/2159-8290.CD-12-0504  0.32
2013 Young RM, Staudt LM. Targeting pathological B cell receptor signalling in lymphoid malignancies. Nature Reviews. Drug Discovery. 12: 229-43. PMID 23449308 DOI: 10.1038/nrd3937  0.32
2013 Chiorazzi M, Rui L, Yang Y, Ceribelli M, Tishbi N, Maurer CW, Ranuncolo SM, Zhao H, Xu W, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, ... ... Staudt LM, et al. Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 3943-8. PMID 23431138 DOI: 10.1073/pnas.1217271110  0.32
2013 O'Shea JJ, Holland SM, Staudt LM. JAKs and STATs in immunity, immunodeficiency, and cancer New England Journal of Medicine. 368: 161-170. PMID 23301733 DOI: 10.1056/NEJMra1202117  0.32
2013 Lim KH, Staudt LM. Toll-like receptor signaling. Cold Spring Harbor Perspectives in Biology. 5: a011247. PMID 23284045 DOI: 10.1101/cshperspect.a011247  0.32
2012 Snow AL, Xiao W, Stinson JR, Lu W, Benjamin CD, Zheng L, Pittaluga S, Matthews HF, Schmitz R, Jhavar S, Kuchen S, Kardava L, Wang W, Lamborn IT, Jing H, ... ... Staudt LM, et al. Congenital B cell lymphocytosis explained by novel germline CARD11 mutations Journal of Experimental Medicine. 209: 2247-2261. PMID 23129749 DOI: 10.1084/jem.20120831  0.32
2012 Shaffer AL, Staudt LM. The case of the missing c-Myc. Nature Immunology. 13: 1029-31. PMID 23080195 DOI: 10.1038/ni.2455  0.32
2012 Wan X, Yeung C, Kim SY, Dolan JG, Ngo VN, Burkett S, Khan J, Staudt LM, Helman LJ. Identification of FoxM1/Bub1b signaling pathway as a required component for growth and survival of rhabdomyosarcoma. Cancer Research. 72: 5889-99. PMID 23002205 DOI: 10.1158/0008-5472.CAN-12-1991  0.32
2012 Sanda T, Lawton LN, Barrasa MI, Fan ZP, Kohlhammer H, Gutierrez A, Ma W, Tatarek J, Ahn Y, Kelliher MA, Jamieson CH, Staudt LM, Young RA, Look AT. Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia. Cancer Cell. 22: 209-21. PMID 22897851 DOI: 10.1016/j.ccr.2012.06.007  0.32
2012 Schmitz R, Young RM, Ceribelli M, Jhavar S, Xiao W, Zhang M, Wright G, Shaffer AL, Hodson DJ, Buras E, Liu X, Powell J, Yang Y, Xu W, Zhao H, ... ... Staudt LM, et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature. 490: 116-20. PMID 22885699 DOI: 10.1038/nature11378  0.32
2012 Johnson NA, Slack GW, Savage KJ, Connors JM, Ben-Neriah S, Rogic S, Scott DW, Tan KL, Steidl C, Sehn LH, Chan WC, Iqbal J, Meyer PN, Lenz G, Wright G, ... ... Staudt LM, et al. Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 3452-9. PMID 22851565 DOI: 10.1200/JCO.2011.41.0985  0.32
2012 Perry AM, Cardesa-Salzmann TM, Meyer PN, Colomo L, Smith LM, Fu K, Greiner TC, Delabie J, Gascoyne RD, Rimsza L, Jaffe ES, Ott G, Rosenwald A, Braziel RM, Tubbs R, ... ... Staudt LM, et al. A new biologic prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphoma. Blood. 120: 2290-6. PMID 22740447 DOI: 10.1182/blood-2012-05-430389  0.32
2012 Huang X, Di Liberto M, Jayabalan D, Liang J, Ely S, Bretz J, Shaffer AL, Louie T, Chen I, Randolph S, Hahn WC, Staudt LM, Niesvizky R, Moore MA, Chen-Kiang S. Prolonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4. Blood. 120: 1095-106. PMID 22718837 DOI: 10.1182/blood-2012-03-415984  0.32
2012 Yang Y, Shaffer AL, Emre NC, Ceribelli M, Zhang M, Wright G, Xiao W, Powell J, Platig J, Kohlhammer H, Young RM, Zhao H, Yang Y, Xu W, Buggy JJ, ... ... Staudt LM, et al. Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma. Cancer Cell. 21: 723-37. PMID 22698399 DOI: 10.1016/j.ccr.2012.05.024  0.32
2012 Kentsis A, Reed C, Rice KL, Sanda T, Rodig SJ, Tholouli E, Christie A, Valk PJ, Delwel R, Ngo V, Kutok JL, Dahlberg SE, Moreau LA, Byers RJ, Christensen JG, ... ... Staudt LM, et al. Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia. Nature Medicine. 18: 1118-22. PMID 22683780 DOI: 10.1038/nm.2819  0.32
2012 Iqbal J, Shen Y, Liu Y, Fu K, Jaffe ES, Liu C, Liu Z, Lachel CM, Deffenbacher K, Greiner TC, Vose JM, Bhagavathi S, Staudt LM, Rimsza L, Rosenwald A, et al. Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis Blood. 119: 4939-4948. PMID 22490335 DOI: 10.1182/blood-2011-07-370122  0.32
2012 Deffenbacher KE, Iqbal J, Sanger W, Shen Y, Lachel C, Liu Z, Liu Y, Lim MS, Perkins SL, Fu K, Smith L, Lynch J, Staudt LM, Rimsza LM, Jaffe E, et al. Molecular distinctions between pediatric and adult mature B-cell non-Hodgkin lymphomas identified through genomic profiling. Blood. 119: 3757-66. PMID 22374697 DOI: 10.1182/blood-2011-05-349662  0.32
2012 Shaffer AL, Young RM, Staudt LM. Pathogenesis of human B cell lymphomas. Annual Review of Immunology. 30: 565-610. PMID 22224767 DOI: 10.1146/annurev-immunol-020711-075027  0.32
2011 Leich E, Zamo A, Horn H, Haralambieva E, Puppe B, Gascoyne RD, Chan WC, Braziel RM, Rimsza LM, Weisenburger DD, Delabie J, Jaffe ES, Fitzgibbon J, Staudt LM, Mueller-Hermelink HK, et al. MicroRNA profiles of t(14;18)-negative follicular lymphoma support a late germinal center B-cell phenotype. Blood. 118: 5550-8. PMID 21960592 DOI: 10.1182/blood-2011-06-361972  0.32
2011 Iqbal J, Meyer PN, Smith LM, Johnson NA, Vose JM, Greiner TC, Connors JM, Staudt LM, Rimsza L, Jaffe E, Rosenwald A, Ott G, Delabie J, Campo E, Braziel RM, et al. BCL2 predicts survival in germinal center B-cell-like diffuse large B-cell lymphoma treated with CHOP-like therapy and rituximab. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7785-95. PMID 21933893 DOI: 10.1158/1078-0432.CCR-11-0267  0.32
2011 Morton LM, Cerhan JR, Hartge P, Vasef MA, Neppalli VT, Natkunam Y, Dogan A, Dave BJ, Jain S, Levy R, Lossos IS, Cozen W, Davis S, Schenk MJ, Maurer MJ, ... ... Staudt LM, et al. Immunostaining to identify molecular subtypes of diffuse large B-cell lymphoma in a population-based epidemiologic study in the pre-rituximab era. International Journal of Molecular Epidemiology and Genetics. 2: 245-52. PMID 21915363  0.32
2011 Eberle FC, Rodriguez-Canales J, Wei L, Hanson JC, Killian JK, Sun HW, Adams LG, Hewitt SM, Wilson WH, Pittaluga S, Meltzer PS, Staudt LM, Emmert-Buck MR, Jaffe ES. Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma. Haematologica. 96: 558-66. PMID 21454882 DOI: 10.3324/haematol.2010.033167  0.32
2011 Steidl C, Shah SP, Woolcock BW, Rui L, Kawahara M, Farinha P, Johnson NA, Zhao Y, Telenius A, Neriah SB, McPherson A, Meissner B, Okoye UC, Diepstra A, van den Berg A, ... ... Staudt LM, et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature. 471: 377-81. PMID 21368758 DOI: 10.1038/nature09754  0.32
2011 Rimsza LM, Wright G, Schwartz M, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Cook JR, Tubbs RR, Braziel RM, Delabie J, Miller TP, Staudt LM. Accurate classification of diffuse large B-cell lymphoma into germinal center and activated B-cell subtypes using a nuclease protection assay on formalin-fixed, paraffin-embedded tissues Clinical Cancer Research. 17: 3727-3732. PMID 21364035 DOI: 10.1158/1078-0432.CCR-10-2573  0.32
2011 Ngo VN, Young RM, Schmitz R, Jhavar S, Xiao W, Lim KH, Kohlhammer H, Xu W, Yang Y, Zhao H, Shaffer AL, Romesser P, Wright G, Powell J, Rosenwald A, ... ... Staudt LM, et al. Oncogenically active MYD88 mutations in human lymphoma. Nature. 470: 115-9. PMID 21179087 DOI: 10.1038/nature09671  0.32
2011 Annunziata CM, Hernandez L, Davis RE, Zingone A, Lamy L, Lam LT, Hurt EM, Shaffer AL, Kuehl WM, Staudt LM. A mechanistic rationale for MEK inhibitor therapy in myeloma based on blockade of MAF oncogene expression. Blood. 117: 2396-404. PMID 21163924 DOI: 10.1182/blood-2010-04-278788  0.32
2011 Meyer PN, Fu K, Greiner TC, Smith LM, Delabie J, Gascoyne RD, Ott G, Rosenwald A, Braziel RM, Campo E, Vose JM, Lenz G, Staudt LM, Chan WC, Weisenburger DD. Immunohistochemical methods for predicting cell of origin and survival in patients with diffuse large B-cell lymphoma treated with rituximab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 200-7. PMID 21135273 DOI: 10.1200/JCO.2010.30.0368  0.32
2011 Martinez-Garcia E, Popovic R, Min DJ, Sweet SM, Thomas PM, Zamdborg L, Heffner A, Will C, Lamy L, Staudt LM, Levens DL, Kelleher NL, Licht JD. The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood. 117: 211-20. PMID 20974671 DOI: 10.1182/blood-2010-07-298349  0.32
2011 Pérez-Galán P, Mora-Jensen H, Weniger MA, Shaffer AL, Rizzatti EG, Chapman CM, Mo CC, Stennett LS, Rader C, Liu P, Raghavachari N, Stetler-Stevenson M, Yuan C, Pittaluga S, Maric I, ... ... Staudt LM, et al. Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation. Blood. 117: 542-52. PMID 20956803 DOI: 10.1182/blood-2010-02-269514  0.32
2010 Rui L, Emre NC, Kruhlak MJ, Chung HJ, Steidl C, Slack G, Wright GW, Lenz G, Ngo VN, Shaffer AL, Xu W, Zhao H, Yang Y, Lamy L, Davis RE, ... ... Staudt LM, et al. Cooperative epigenetic modulation by cancer amplicon genes. Cancer Cell. 18: 590-605. PMID 21156283 DOI: 10.1016/j.ccr.2010.11.013  0.32
2010 Milhollen MA, Traore T, Adams-Duffy J, Thomas MP, Berger AJ, Dang L, Dick LR, Garnsey JJ, Koenig E, Langston SP, Manfredi M, Narayanan U, Rolfe M, Staudt LM, Soucy TA, et al. MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma. Blood. 116: 1515-23. PMID 20525923 DOI: 10.1182/blood-2010-03-272567  0.32
2010 Hartmann EM, Campo E, Wright G, Lenz G, Salaverria I, Jares P, Xiao W, Braziel RM, Rimsza LM, Chan WC, Weisenburger DD, Delabie J, Jaffe ES, Gascoyne RD, Dave SS, ... ... Staudt LM, et al. Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling. Blood. 116: 953-61. PMID 20421449 DOI: 10.1182/blood-2010-01-263806  0.32
2010 Steidl C, Lee T, Shah SP, Farinha P, Han G, Nayar T, Delaney A, Jones SJ, Iqbal J, Weisenburger DD, Bast MA, Rosenwald A, Muller-Hermelink HK, Rimsza LM, Campo E, ... ... Staudt LM, et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma New England Journal of Medicine. 362: 875-885. PMID 20220182 DOI: 10.1056/NEJMoa0905680  0.32
2010 Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang Y, Xu W, Shaffer AL, Wright G, Xiao W, Powell J, ... ... Staudt LM, et al. Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature. 463: 88-92. PMID 20054396 DOI: 10.1038/nature08638  0.32
2009 Hailfinger S, Lenz G, Ngo V, Posvitz-Fejfar A, Rebeaud F, Guzzardi M, Penas EM, Dierlamm J, Chan WC, Staudt LM, Thome M. Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 106: 19946-51. PMID 19897720 DOI: 10.1073/pnas.0907511106  0.32
2009 Mozos A, Royo C, Hartmann E, De Jong D, Baró C, Valera A, Fu K, Weisenburger DD, Delabie J, Chuang SS, Jaffe ES, Ruiz-Marcellan C, Dave S, Rimsza L, Braziel R, ... ... Staudt LM, et al. SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype. Haematologica. 94: 1555-62. PMID 19880778 DOI: 10.3324/haematol.2009.010264  0.32
2009 Wilkinson ST, Fernandez DR, Murphy SP, Braziel RM, Campo E, Chan WC, Delabie J, Gascoyne RD, Staudt LM, Jaffe ES, Rosenwald A, Rimsza LM. Decreased major histocompatibility complex class II expression in diffuse large B-cell lymphoma does not correlate with CpG methylation of class II transactivator promoters III and IV. Leukemia & Lymphoma. 50: 1875-8. PMID 19814686 DOI: 10.3109/10428190903297531  0.32
2009 Choi WW, Weisenburger DD, Greiner TC, Piris MA, Banham AH, Delabie J, Braziel RM, Geng H, Iqbal J, Lenz G, Vose JM, Hans CP, Fu K, Smith LM, Li M, ... ... Staudt LM, et al. A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5494-502. PMID 19706817 DOI: 10.1158/1078-0432.CCR-09-0113  0.32
2009 Leich E, Salaverria I, Bea S, Zettl A, Wright G, Moreno V, Gascoyne RD, Chan WC, Braziel RM, Rimsza LM, Weisenburger DD, Delabie J, Jaffe ES, Lister A, Fitzgibbon J, ... Staudt LM, et al. Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations. Blood. 114: 826-34. PMID 19471018 DOI: 10.1182/blood-2009-01-198580  0.32
2009 Shaffer AL, Emre NC, Romesser PB, Staudt LM. IRF4: Immunity. Malignancy! Therapy? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2954-61. PMID 19383829 DOI: 10.1158/1078-0432.CCR-08-1845  0.32
2009 Dunleavy K, Pittaluga S, Czuczman MS, Dave SS, Wright G, Grant N, Shovlin M, Jaffe ES, Janik JE, Staudt LM, Wilson WH. Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma. Blood. 113: 6069-76. PMID 19380866 DOI: 10.1182/blood-2009-01-199679  0.32
2009 Faumont N, Durand-Panteix S, Schlee M, Grömminger S, Schuhmacher M, Hölzel M, Laux G, Mailhammer R, Rosenwald A, Staudt LM, Bornkamm GW, Feuillard J. c-Myc and Rel/NF-κB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells Journal of Virology. 83: 5014-5027. PMID 19264782 DOI: 10.1128/JVI.02264-08  0.32
2009 O'Shea D, O'Riain C, Gupta M, Waters R, Yang Y, Wrench D, Gribben J, Rosenwald A, Ott G, Rimsza LM, Holte H, Cazier JB, Johnson NA, Campo E, Chan WC, ... ... Staudt LM, et al. Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation. Blood. 113: 2298-301. PMID 19141865 DOI: 10.1182/blood-2008-08-174953  0.32
2009 Bidère N, Ngo VN, Lee J, Collins C, Zheng L, Wan F, Davis RE, Lenz G, Anderson DE, Arnoult D, Vazquez A, Sakai K, Zhang J, Meng Z, Veenstra TD, ... Staudt LM, et al. Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival. Nature. 458: 92-6. PMID 19118383 DOI: 10.1038/nature07613  0.32
2000 Shaffer AL, Yu X, He Y, Boldrick J, Chan EP, Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity. 13: 199-212. PMID 10981963  0.32
1996 Seyfert VL, Allman D, He Y, Staudt LM. Transcriptional repression by the proto-oncogene BCL-6. Oncogene. 12: 2331-42. PMID 8649773  0.52
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