Leonard Freedman - Publications

Weill Cornell Medical College, New York, NY, United States 
Cell Biology

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Shen Q, Bai Y, Chang KC, Wang Y, Burris TP, Freedman LP, Thompson CC, Nagpal S. Liver X receptor-retinoid X receptor (LXR-RXR) heterodimer cistrome reveals coordination of LXR and AP1 signaling in keratinocytes. The Journal of Biological Chemistry. 286: 14554-63. PMID 21349840 DOI: 10.1074/jbc.M110.165704  0.36
2010 Schmidt A, Kimmel DB, Bai C, Scafonas A, Rutledge S, Vogel RL, McElwee-Witmer S, Chen F, Nantermet PV, Kasparcova V, Leu CT, Zhang HZ, Duggan ME, Gentile MA, Hodor P, ... ... Freedman LP, et al. Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology. The Journal of Biological Chemistry. 285: 17054-64. PMID 20356837 DOI: 10.1074/jbc.M109.099002  0.36
2010 Chang KC, Wang Y, Oh IG, Jenkins S, Freedman LP, Thompson CC, Chung JH, Nagpal S. Estrogen receptor beta is a novel therapeutic target for photoaging. Molecular Pharmacology. 77: 744-50. PMID 20110405 DOI: 10.1124/mol.109.062877  0.36
2008 Chang KC, Shen Q, Oh IG, Jelinsky SA, Jenkins SF, Wang W, Wang Y, LaCava M, Yudt MR, Thompson CC, Freedman LP, Chung JH, Nagpal S. Liver X receptor is a therapeutic target for photoaging and chronological skin aging. Molecular Endocrinology (Baltimore, Md.). 22: 2407-19. PMID 18787039 DOI: 10.1210/me.2008-0232  0.36
2008 Cheskis BJ, Greger J, Cooch N, McNally C, Mclarney S, Lam HS, Rutledge S, Mekonnen B, Hauze D, Nagpal S, Freedman LP. MNAR plays an important role in ERa activation of Src/MAPK and PI3K/Akt signaling pathways. Steroids. 73: 901-5. PMID 18261753 DOI: 10.1016/j.steroids.2007.12.028  0.36
2008 Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. The Embo Journal. 27: 535-45. PMID 18219273 DOI: 10.1038/sj.emboj.7601984  0.36
2007 Cheskis BJ, Greger JG, Nagpal S, Freedman LP. Signaling by estrogens. Journal of Cellular Physiology. 213: 610-7. PMID 17886255 DOI: 10.1002/jcp.21253  0.36
2007 Greger JG, Fursov N, Cooch N, McLarney S, Freedman LP, Edwards DP, Cheskis BJ. Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 27: 1904-13. PMID 17194752 DOI: 10.1128/MCB.01732-06  0.36
2006 Lipfert L, Fisher JE, Wei N, Scafonas A, Su Q, Yudkovitz J, Chen F, Warrier S, Birzin ET, Kim S, Chen HY, Tan Q, Schmidt A, Dininno F, Rohrer SP, ... ... Freedman LP, et al. Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation. Molecular Endocrinology (Baltimore, Md.). 20: 516-33. PMID 16223974 DOI: 10.1210/me.2005-0190  0.36
2005 Bettoun DJ, Scafonas A, Rutledge SJ, Hodor P, Chen O, Gambone C, Vogel R, McElwee-Witmer S, Bai C, Freedman L, Schmidt A. Interaction between the androgen receptor and RNase L mediates a cross-talk between the interferon and androgen signaling pathways. The Journal of Biological Chemistry. 280: 38898-901. PMID 16166078 DOI: 10.1074/jbc.C500324200  0.36
2005 Tan Q, Blizzard TA, Morgan JD, Birzin ET, Chan W, Yang YT, Pai LY, Hayes EC, DaSilva CA, Warrier S, Yudkovitz J, Wilkinson HA, Sharma N, Fitzgerald PM, Li S, ... ... Freedman LP, et al. Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs. Bioorganic & Medicinal Chemistry Letters. 15: 1675-81. PMID 15745820 DOI: 10.1016/j.bmcl.2005.01.046  0.36
2004 Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD. Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in VDR transactivation during keratinocyte differentiation. The Journal of Steroid Biochemistry and Molecular Biology. 89: 273-6. PMID 15225784 DOI: 10.1016/j.jsbmb.2004.03.106  0.36
2004 Pineda Torra I, Freedman LP, Garabedian MJ. Identification of DRIP205 as a coactivator for the Farnesoid X receptor. The Journal of Biological Chemistry. 279: 36184-91. PMID 15187081 DOI: 10.1074/jbc.M405126200  0.36
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/j.molcel.2004.05.011  0.36
2003 Oda Y, Sihlbom C, Chalkley RJ, Huang L, Rachez C, Chang CP, Burlingame AL, Freedman LP, Bikle DD. Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation. Molecular Endocrinology (Baltimore, Md.). 17: 2329-39. PMID 12893881 DOI: 10.1210/me.2003-0063  0.36
2003 Lau JF, Nusinzon I, Burakov D, Freedman LP, Horvath CM. Role of metazoan mediator proteins in interferon-responsive transcription. Molecular and Cellular Biology. 23: 620-8. PMID 12509459 DOI: 10.1128/MCB.23.2.620-628.2003  0.36
2002 Maeda Y, Rachez C, Hawel L, Byus CV, Freedman LP, Sladek FM. Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205. Molecular Endocrinology (Baltimore, Md.). 16: 1502-10. PMID 12089346 DOI: 10.1210/mend.16.7.0883  0.36
2002 Gamble MJ, Freedman LP. A coactivator code for transcription. Trends in Biochemical Sciences. 27: 165-7. PMID 11943535 DOI: 10.1016/S0968-0004(02)02076-5  0.36
2002 Burakov D, Crofts LA, Chang CP, Freedman LP. Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor. The Journal of Biological Chemistry. 277: 14359-62. PMID 11893728 DOI: 10.1074/jbc.C200099200  0.36
2002 Staeva-Vieira TP, Freedman LP. 1,25-dihydroxyvitamin D3 inhibits IFN-gamma and IL-4 levels during in vitro polarization of primary murine CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 1181-9. PMID 11801653  1
2000 Bromleigh VC, Freedman LP. p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. Genes & Development. 14: 2581-6. PMID 11040212  1
2000 Burakov D, Wong CW, Rachez C, Cheskis BJ, Freedman LP. Functional interactions between the estrogen receptor and DRIP205, a subunit of the heteromeric DRIP coactivator complex. The Journal of Biological Chemistry. 275: 20928-34. PMID 10770935 DOI: 10.1074/jbc.M002013200  0.36
1999 Hittelman AB, Burakov D, Iñiguez-Lluhí JA, Freedman LP, Garabedian MJ. Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins. The Embo Journal. 18: 5380-8. PMID 10508170 DOI: 10.1093/emboj/18.19.5380  0.36
1998 Rachez C, Suldan Z, Ward J, Chang CP, Burakov D, Erdjument-Bromage H, Tempst P, Freedman LP. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system. Genes & Development. 12: 1787-800. PMID 9637681  0.36
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