Ormond A. MacDougald - Publications

University of Michigan, Ann Arbor, Ann Arbor, MI 
Molecular Biology, Cell Biology, Animal Physiology Biology

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kang Q, Zhu X, Ren D, Ky A, MacDougald OA, O'Rourke RW, Rui L. Adipose METTL14-Elicited N -Methyladenosine Promotes Obesity, Insulin Resistance, and NAFLD Through Suppressing β Adrenergic Signaling and Lipolysis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2301645. PMID 37526326 DOI: 10.1002/advs.202301645  0.31
2021 Bagchi DP, MacDougald OA. Wnt Signaling: From Mesenchymal Cell Fate to Lipogenesis and Other Mature Adipocyte Functions. Diabetes. PMID 34155042 DOI: 10.2337/dbi20-0015  0.338
2020 Bagchi DP, Nishii A, Li Z, DelProposto JB, Corsa CA, Mori H, Hardij J, Learman BS, Lumeng CN, MacDougald OA. Wnt/β-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells. Molecular Metabolism. 101078. PMID 32919095 DOI: 10.1016/J.Molmet.2020.101078  0.447
2020 Alejandro EU, Jo S, Akhaphong B, Llacer PR, Gianchandani M, Gregg B, Parlee SD, MacDougald OA, Bernal-Mizrachi E. Maternal low-protein diet on the last week of pregnancy contributes to insulin resistance and β-cell dysfunction in the mouse offspring. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 32877242 DOI: 10.1152/Ajpregu.00284.2019  0.317
2020 Suchacki KJ, Tavares AAS, Mattiucci D, Scheller EL, Papanastasiou G, Gray C, Sinton MC, Ramage LE, McDougald WA, Lovdel A, Sulston RJ, Thomas BJ, Nicholson BM, Drake AJ, Alcaide-Corral CJ, ... ... MacDougald OA, et al. Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis. Nature Communications. 11: 3097. PMID 32555194 DOI: 10.1038/S41467-020-16878-2  0.336
2020 Bagchi DP, Li Z, Corsa CA, Hardij J, Mori H, Learman BS, Lewis KT, Schill RL, Romanelli SM, MacDougald OA. Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction. Molecular Metabolism. 100992. PMID 32325263 DOI: 10.1016/J.Molmet.2020.100992  0.437
2019 Craft CS, Robles H, Lorenz MR, Hilker ED, Magee KL, Andersen TL, Cawthorn WP, MacDougald OA, Harris CA, Scheller EL. Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling. Scientific Reports. 9: 17427. PMID 31758074 DOI: 10.1038/S41598-019-54036-X  0.453
2019 Benchamana A, Mori H, MacDougald OA, Soodvilai S. Regulation of adipocyte differentiation and metabolism by lansoprazole. Life Sciences. 116897. PMID 31644894 DOI: 10.1016/J.Lfs.2019.116897  0.39
2019 Chen N, Schill RL, O'Donnell M, Xu K, Bagchi DP, MacDougald OA, Koenig RJ, Xu B. The transcription factor NKX1-2 promotes adipogenesis and may contribute to a balance between adipocyte and osteoblast differentiation. The Journal of Biological Chemistry. PMID 31615896 DOI: 10.1074/Jbc.Ra119.007967  0.444
2019 Li Z, MacDougald OA. Stem cell factor: the bridge between bone marrow adipocytes and hematopoietic cells. Haematologica. 104: 1689-1691. PMID 31473604 DOI: 10.3324/Haematol.2019.224188  0.376
2019 Bagchi DP, MacDougald OA. Identification and Dissection of Diverse Mouse Adipose Depots. Journal of Visualized Experiments : Jove. PMID 31355801 DOI: 10.3791/59499  0.327
2019 Kasza I, Adler D, Nelson DW, Eric Yen CL, Dumas S, Ntambi JM, MacDougald OA, Hernando D, Porter WP, Best FA, Alexander CM. Evaporative cooling provides a major metabolic energy sink. Molecular Metabolism. PMID 31302039 DOI: 10.1016/J.Molmet.2019.06.023  0.304
2019 Hafner H, Chang E, Carlson Z, Zhu A, Varghese M, Clemente J, Abrishami S, Bagchi DP, MacDougald OA, Singer K, Gregg B. Lactational High-Fat Diet Exposure Programs Metabolic Inflammation and Bone Marrow Adiposity in Male Offspring. Nutrients. 11. PMID 31234301 DOI: 10.3390/Nu11061393  0.342
2019 Corsa CAS, Pearson GL, Renberg A, Askar MM, Vozheiko T, MacDougald OA, Soleimanpour SA. The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic β cells and adipocytes. The Journal of Biological Chemistry. PMID 30877201 DOI: 10.1074/Jbc.Ra118.006763  0.356
2019 PEARSON G, CORSA C, SOLEIMANPOUR S, MACDOUGALD OA. 2013-P: Parkin Is Dispensable in Pancreatic Beta Cells and Adipocytes for Metabolic Homeostasis Diabetes. 68: 2013-P. DOI: 10.2337/Db19-2013-P  0.366
2018 Corsa CAS, MacDougald OA. Cyclical Dedifferentiation and Redifferentiation of Mammary Adipocytes. Cell Metabolism. 28: 187-189. PMID 30089239 DOI: 10.1016/J.Cmet.2018.07.013  0.326
2018 Scheller EL, Khandaker S, Learman BS, Cawthorn WP, Anderson LM, Pham HA, Robles H, Wang Z, Li Z, Parlee SD, Simon BR, Mori H, Bree AJ, Craft CS, MacDougald OA. Bone marrow adipocytes resist lipolysis and remodeling in response to β-adrenergic stimulation. Bone. PMID 29360620 DOI: 10.1016/J.Bone.2018.01.016  0.376
2018 Li Z, Hardij J, Bagchi DP, Scheller EL, MacDougald OA. Development, regulation, metabolism and function of bone marrow adipose tissues. Bone. PMID 29343445 DOI: 10.1016/J.Bone.2018.01.008  0.382
2017 Ge C, Zhao G, Li B, Li Y, Cawthorn WP, MacDougald OA, Franceschi RT. Genetic inhibition of PPARγ S112 phosphorylation reduces bone formation and stimulates marrow adipogenesis. Bone. PMID 29107124 DOI: 10.1016/J.Bone.2017.10.023  0.378
2017 Ma X, Pham VT, Mori H, MacDougald OA, Shah YM, Bodary PF. Iron elevation and adipose tissue remodeling in the epididymal depot of a mouse model of polygenic obesity. Plos One. 12: e0179889. PMID 28651003 DOI: 10.1371/Journal.Pone.0179889  0.308
2016 Scheller EL, Doucette CR, Learman BS, Cawthorn WP, Khandaker S, Schell B, Wu B, Ding SY, Bredella MA, Fazeli PK, Khoury B, Jepsen KJ, Pilch PF, Klibanski A, Rosen CJ, ... MacDougald OA, et al. Corrigendum: Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nature Communications. 7: 13775. PMID 27929114 DOI: 10.1038/Ncomms13775  0.307
2016 Sulston RJ, Learman BS, Zhang B, Scheller EL, Parlee SD, Simon BR, Mori H, Bree AJ, Wallace RJ, Krishnan V, MacDougald OA, Cawthorn WP. Increased Circulating Adiponectin in Response to Thiazolidinediones: Investigating the Role of Bone Marrow Adipose Tissue. Frontiers in Endocrinology. 7: 128. PMID 27708617 DOI: 10.3389/Fendo.2016.00128  0.368
2016 Chkourko Gusky H, Diedrich J, MacDougald OA, Podgorski I. Omentum and bone marrow: how adipocyte-rich organs create tumour microenvironments conducive for metastatic progression. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 17: 1015-1029. PMID 27432523 DOI: 10.1111/Obr.12450  0.367
2016 Qiang G, Whang Kong H, Xu S, Pham HA, Parlee SD, Burr AA, Gil V, Pang J, Hughes A, Gu X, Fantuzzi G, MacDougald OA, Liew CW. Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation. Molecular Metabolism. 5: 480-90. PMID 27408774 DOI: 10.1016/J.Molmet.2016.05.005  0.397
2016 Chen YS, Wu R, Yang X, Kou S, MacDougald OA, Yu L, Shi H, Xue B. Inhibiting DNA methylation switches adipogenesis to osteoblastogenesis by activating Wnt10a. Scientific Reports. 6: 25283. PMID 27136753 DOI: 10.1038/Srep25283  0.341
2016 Scheller EL, Cawthorn WP, Burr AA, Horowitz MC, MacDougald OA. Marrow Adipose Tissue: Trimming the Fat. Trends in Endocrinology and Metabolism: Tem. PMID 27094502 DOI: 10.1016/J.Tem.2016.03.016  0.325
2016 Mori H, Yao Y, Learman BS, Kurozumi K, Ishida J, Ramakrishnan SK, Overmyer KA, Xue X, Cawthorn WP, Reid MA, Taylor M, Ning X, Shah YM, MacDougald OA. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Scientific Reports. 6: 21520. PMID 26861754 DOI: 10.1038/Srep21520  0.358
2016 Ge C, Cawthorn WP, Li Y, Zhao G, Macdougald OA, Franceschi RT. Reciprocal Control of Osteogenic and Adipogenic Differentiation by ERK/MAP Kinase Phosphorylation of Runx2 and PPARγ Transcription Factors. Journal of Cellular Physiology. 231: 587-96. PMID 26206105 DOI: 10.1002/Jcp.25102  0.375
2016 Qiang G, Whang Kong H, Xu S, Pham HA, Parlee SD, Burr AA, Gil V, Pang J, Hughes A, Gu X, Fantuzzi G, MacDougald OA, Liew CW. Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation Molecular Metabolism. DOI: 10.1016/j.molmet.2016.05.005  0.301
2015 Cawthorn WP, Scheller EL, Parlee SD, Pham HA, Learman BS, Redshaw CM, Sulston RJ, Burr AA, Das AK, Simon BR, Mori H, Bree AJ, Schell B, Krishnan V, MacDougald OA. Expansion of bone marrow adipose tissue during caloric restriction is associated with increased circulating glucocorticoids and not with hypoleptinemia. Endocrinology. en20151477. PMID 26696121 DOI: 10.1210/En.2015-1477  0.307
2015 Scheller EL, Doucette CR, Learman BS, Cawthorn WP, Khandaker S, Schell B, Wu B, Ding SY, Bredella MA, Fazeli PK, Khoury B, Jepsen KJ, Pilch PF, Klibanski A, Rosen CJ, ... MacDougald OA, et al. Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nature Communications. 6: 7808. PMID 26245716 DOI: 10.1038/Ncomms8808  0.427
2015 Zhang J, Motyl KJ, Irwin R, MacDougald OA, Britton RA, McCabe LR. Loss of bone and Wnt10b expression in male type 1 diabetic mice is blocked by the probiotic L. reuteri. Endocrinology. EN20151308. PMID 26135835 DOI: 10.1210/En.2015-1308  0.306
2015 Doucette CR, Horowitz MC, Berry R, MacDougald OA, Anunciado-Koza R, Koza RA, Rosen CJ. A High Fat Diet Increases Bone Marrow Adipose Tissue (MAT) But Does Not Alter Trabecular or Cortical Bone Mass in C57BL/6J Mice. Journal of Cellular Physiology. 230: 2032-7. PMID 25663195 DOI: 10.1002/Jcp.24954  0.311
2014 Kasza I, Suh Y, Wollny D, Clark RJ, Roopra A, Colman RJ, MacDougald OA, Shedd TA, Nelson DW, Yen MI, Yen CL, Alexander CM. Syndecan-1 is required to maintain intradermal fat and prevent cold stress. Plos Genetics. 10: e1004514. PMID 25101993 DOI: 10.1371/Journal.Pgen.1004514  0.359
2014 Cawthorn WP, Scheller EL, Learman BS, Parlee SD, Simon BR, Mori H, Ning X, Bree AJ, Schell B, Broome DT, Soliman SS, DelProposto JL, Lumeng CN, Mitra A, Pandit SV, ... ... MacDougald OA, et al. Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction. Cell Metabolism. 20: 368-75. PMID 24998914 DOI: 10.1016/J.Cmet.2014.06.003  0.353
2014 Bornstein S, Brown SA, Le PT, Wang X, DeMambro V, Horowitz MC, MacDougald O, Baron R, Lotinun S, Karsenty G, Wei W, Ferron M, Kovacs CS, Clemmons D, Wan Y, et al. FGF-21 and skeletal remodeling during and after lactation in C57BL/6J mice. Endocrinology. 155: 3516-26. PMID 24914939 DOI: 10.1210/En.2014-1083  0.344
2014 Liu S, Xu R, Gerin I, Cawthorn WP, Macdougald OA, Chen XW, Saltiel AR, Koenig RJ, Xu B. SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling. Plos One. 9: e95416. PMID 24743795 DOI: 10.1371/Journal.Pone.0095416  0.394
2014 Scheller EL, Troiano N, Vanhoutan JN, Bouxsein MA, Fretz JA, Xi Y, Nelson T, Katz G, Berry R, Church CD, Doucette CR, Rodeheffer MS, Macdougald OA, Rosen CJ, Horowitz MC. Use of osmium tetroxide staining with microcomputerized tomography to visualize and quantify bone marrow adipose tissue in vivo. Methods in Enzymology. 537: 123-39. PMID 24480344 DOI: 10.1016/B978-0-12-411619-1.00007-0  0.327
2014 Parlee SD, Lentz SI, Mori H, MacDougald OA. Quantifying size and number of adipocytes in adipose tissue. Methods in Enzymology. 537: 93-122. PMID 24480343 DOI: 10.1016/B978-0-12-411619-1.00006-9  0.35
2014 Simon BR, Learman BS, Parlee SD, Scheller EL, Mori H, Cawthorn WP, Ning X, Krishnan V, Ma YL, Tyrberg B, MacDougald OA. Sweet taste receptor deficient mice have decreased adiposity and increased bone mass. Plos One. 9: e86454. PMID 24466105 DOI: 10.1371/Journal.Pone.0086454  0.392
2014 Parlee SD, Simon BR, Scheller EL, Alejandro EU, Learman BS, Krishnan V, Bernal-Mizrachi E, MacDougald OA. Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females. Endocrinology. 155: 1313-26. PMID 24456165 DOI: 10.1210/En.2013-1995  0.336
2014 Parlee SD, MacDougald OA. Maternal nutrition and risk of obesity in offspring: the Trojan horse of developmental plasticity. Biochimica Et Biophysica Acta. 1842: 495-506. PMID 23871838 DOI: 10.1016/J.Bbadis.2013.07.007  0.314
2013 Simon BR, Parlee SD, Learman BS, Mori H, Scheller EL, Cawthorn WP, Ning X, Gallagher K, Tyrberg B, Assadi-Porter FM, Evans CR, MacDougald OA. Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors. The Journal of Biological Chemistry. 288: 32475-89. PMID 24068707 DOI: 10.1074/Jbc.M113.514034  0.392
2013 Du B, Cawthorn WP, Su A, Doucette CR, Yao Y, Hemati N, Kampert S, McCoin C, Broome DT, Rosen CJ, Yang G, MacDougald OA. The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-β (TGFβ) signaling. The Journal of Biological Chemistry. 288: 3036-47. PMID 23250756 DOI: 10.1074/Jbc.M112.440370  0.514
2012 Mori H, Prestwich TC, Reid MA, Longo KA, Gerin I, Cawthorn WP, Susulic VS, Krishnan V, Greenfield A, Macdougald OA. Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition. The Journal of Clinical Investigation. 122: 2405-16. PMID 22728933 DOI: 10.1172/Jci63604  0.79
2012 Cawthorn WP, Scheller EL, MacDougald OA. Adipose tissue stem cells: the great WAT hope. Trends in Endocrinology and Metabolism: Tem. 23: 270-7. PMID 22417866 DOI: 10.1016/J.Tem.2012.01.003  0.312
2012 Akhmetshina A, Palumbo K, Dees C, Bergmann C, Venalis P, Zerr P, Horn A, Kireva T, Beyer C, Zwerina J, Schneider H, Sadowski A, Riener MO, MacDougald OA, Distler O, et al. Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nature Communications. 3: 735. PMID 22415826 DOI: 10.1038/Ncomms1734  0.363
2012 Cawthorn WP, Scheller EL, MacDougald OA. Adipose tissue stem cells meet preadipocyte commitment: going back to the future. Journal of Lipid Research. 53: 227-46. PMID 22140268 DOI: 10.1194/Jlr.R021089  0.352
2012 Rosen C, Karsenty G, MacDougald O. Foreword: interactions between bone and adipose tissue and metabolism. Bone. 50: 429. PMID 22015817 DOI: 10.1016/J.Bone.2011.10.006  0.304
2012 Cawthorn WP, Bree AJ, Yao Y, Du B, Hemati N, Martinez-Santibañez G, MacDougald OA. Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism. Bone. 50: 477-89. PMID 21872687 DOI: 10.1016/J.Bone.2011.08.010  0.416
2011 Wen X, Cawthorn WP, MacDougald OA, Stupp SI, Snead ML, Zhou Y. The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression. Biomaterials. 32: 6478-86. PMID 21663957 DOI: 10.1016/J.Biomaterials.2011.05.045  0.446
2011 Wei J, Melichian D, Komura K, Hinchcliff M, Lam AP, Lafyatis R, Gottardi CJ, MacDougald OA, Varga J. Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis and Rheumatism. 63: 1707-17. PMID 21370225 DOI: 10.1002/Art.30312  0.362
2011 Bommer GT, MacDougald OA. Regulation of lipid homeostasis by the bifunctional SREBF2-miR33a locus. Cell Metabolism. 13: 241-7. PMID 21356514 DOI: 10.1016/J.Cmet.2011.02.004  0.351
2011 Susperreguy S, Prendes LP, Desbats MA, Charó NL, Brown K, MacDougald OA, Kerppola T, Schwartz J, Piwien-Pilipuk G. Visualization by BiFC of different C/EBPβ dimers and their interaction with HP1α reveals a differential subnuclear distribution of complexes in living cells. Experimental Cell Research. 317: 706-23. PMID 21122806 DOI: 10.1016/J.Yexcr.2010.11.008  0.387
2010 Xu B, Gerin I, Miao H, Vu-Phan D, Johnson CN, Xu R, Chen XW, Cawthorn WP, MacDougald OA, Koenig RJ. Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity. Plos One. 5: e14199. PMID 21152033 DOI: 10.1371/Journal.Pone.0014199  0.446
2010 Gerin I, Clerbaux LA, Haumont O, Lanthier N, Das AK, Burant CF, Leclercq IA, MacDougald OA, Bommer GT. Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. The Journal of Biological Chemistry. 285: 33652-61. PMID 20732877 DOI: 10.1074/Jbc.M110.152090  0.314
2010 Kawai M, Sousa KM, MacDougald OA, Rosen CJ. The many facets of PPARgamma: novel insights for the skeleton. American Journal of Physiology. Endocrinology and Metabolism. 299: E3-9. PMID 20407009 DOI: 10.1152/Ajpendo.00157.2010  0.43
2009 Mori H, Inoki K, Opland D, Münzberg H, Villanueva EC, Faouzi M, Ikenoue T, Kwiatkowski DJ, Macdougald OA, Myers MG, Guan KL. Critical roles for the TSC-mTOR pathway in β-cell function. American Journal of Physiology. Endocrinology and Metabolism. 297: E1013-22. PMID 19690069 DOI: 10.1152/Ajpendo.00262.2009  0.375
2009 Mori H, Inoki K, Münzberg H, Opland D, Faouzi M, Villanueva EC, Ikenoue T, Kwiatkowski D, MacDougald OA, Myers MG, Guan KL. Critical role for hypothalamic mTOR activity in energy balance. Cell Metabolism. 9: 362-74. PMID 19356717 DOI: 10.1016/J.Cmet.2009.03.005  0.371
2009 Gerin I, Bommer GT, Lidell ME, Cederberg A, Enerback S, Macdougald OA. On the role of FOX transcription factors in adipocyte differentiation and insulin-stimulated glucose uptake. The Journal of Biological Chemistry. 284: 10755-63. PMID 19244248 DOI: 10.1074/Jbc.M809115200  0.472
2009 Gerin I, Louis GW, Zhang X, Prestwich TC, Kumar TR, Myers MG, Macdougald OA, Nothnick WB. Hyperphagia and obesity in female mice lacking tissue inhibitor of metalloproteinase-1. Endocrinology. 150: 1697-704. PMID 19036876 DOI: 10.1210/En.2008-1409  0.782
2008 Fox KE, Colton LA, Erickson PF, Friedman JE, Cha HC, Keller P, MacDougald OA, Klemm DJ. Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation. The Journal of Biological Chemistry. 283: 35096-105. PMID 18957421 DOI: 10.1074/Jbc.M806423200  0.365
2008 Kennell JA, Gerin I, MacDougald OA, Cadigan KM. The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 15417-22. PMID 18824696 DOI: 10.1073/Pnas.0807763105  0.766
2008 Luo W, Shitaye H, Friedman M, Bennett CN, Miller J, Macdougald OA, Hankenson KD. Disruption of cell-matrix interactions by heparin enhances mesenchymal progenitor adipocyte differentiation. Experimental Cell Research. 314: 3382-91. PMID 18674534 DOI: 10.1016/J.Yexcr.2008.07.003  0.755
2008 Park KW, Waki H, Villanueva CJ, Monticelli LA, Hong C, Kang S, MacDougald OA, Goldrath AW, Tontonoz P. Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Molecular Endocrinology (Baltimore, Md.). 22: 2038-48. PMID 18562627 DOI: 10.1210/Me.2007-0454  0.487
2008 Cha HC, Oak NR, Kang S, Tran TA, Kobayashi S, Chiang SH, Tenen DG, MacDougald OA. Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes. The Journal of Biological Chemistry. 283: 18002-11. PMID 18408001 DOI: 10.1074/Jbc.M800419200  0.409
2008 Keller P, Petrie JT, De Rose P, Gerin I, Wright WS, Chiang SH, Nielsen AR, Fischer CP, Pedersen BK, MacDougald OA. Fat-specific protein 27 regulates storage of triacylglycerol. The Journal of Biological Chemistry. 283: 14355-65. PMID 18334488 DOI: 10.1074/Jbc.M708323200  0.408
2008 Huang X, Charbeneau RA, Fu Y, Kaur K, Gerin I, MacDougald OA, Neubig RR. Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele. Diabetes. 57: 77-85. PMID 17928396 DOI: 10.2337/Db07-0599  0.364
2007 Prestwich TC, Macdougald OA. Wnt/beta-catenin signaling in adipogenesis and metabolism. Current Opinion in Cell Biology. 19: 612-7. PMID 17997088 DOI: 10.1016/J.Ceb.2007.09.014  0.784
2007 MacDougald OA, Burant CF. The rapidly expanding family of adipokines. Cell Metabolism. 6: 159-61. PMID 17767903 DOI: 10.1016/J.Cmet.2007.08.010  0.316
2007 Bennett CN, Ouyang H, Ma YL, Zeng Q, Gerin I, Sousa KM, Lane TF, Krishnan V, Hankenson KD, MacDougald OA. Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1924-32. PMID 17708715 DOI: 10.1359/Jbmr.070810  0.72
2007 Palpant NJ, Yasuda S, MacDougald O, Metzger JM. Non-canonical Wnt signaling enhances differentiation of Sca1+/c-kit+ adipose-derived murine stromal vascular cells into spontaneously beating cardiac myocytes. Journal of Molecular and Cellular Cardiology. 43: 362-70. PMID 17706246 DOI: 10.1016/J.Yjmcc.2007.06.012  0.342
2007 Aslanidi G, Kroutov V, Philipsberg G, Lamb K, Campbell-Thompson M, Walter GA, Kurenov S, Ignacio Aguirre J, Keller P, Hankenson K, Macdougald OA, Zolotukhin S. Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats. American Journal of Physiology. Endocrinology and Metabolism. 293: E726-36. PMID 17578883 DOI: 10.1152/Ajpendo.00248.2007  0.448
2007 Datta J, Majumder S, Kutay H, Motiwala T, Frankel W, Costa R, Cha HC, MacDougald OA, Jacob ST, Ghoshal K. Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Research. 67: 2736-46. PMID 17363595 DOI: 10.1158/0008-5472.Can-06-4433  0.414
2007 Kang S, Bennett CN, Gerin I, Rapp LA, Hankenson KD, MacDougald OA. Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein α and peroxisome proliferator-activated receptor γ Journal of Biological Chemistry. 282: 14515-14524. PMID 17351296 DOI: 10.1074/Jbc.M700030200  0.783
2007 Wright WS, Longo KA, Dolinsky VW, Gerin I, Kang S, Bennett CN, Chiang SH, Prestwich TC, Gress C, Burant CF, Susulic VS, MacDougald OA. Wnt10b inhibits obesity in ob/ob and agouti mice. Diabetes. 56: 295-303. PMID 17259372 DOI: 10.2337/Db06-1339  0.768
2007 Xu Y, Zhou YL, Erickson RL, Macdougald OA, Snead ML. Physical dissection of the CCAAT/enhancer-binding protein alpha in regulating the mouse amelogenin gene. Biochemical and Biophysical Research Communications. 354: 56-61. PMID 17210130 DOI: 10.1016/J.Bbrc.2006.12.182  0.323
2006 Rosen ED, MacDougald OA. Adipocyte differentiation from the inside out. Nature Reviews. Molecular Cell Biology. 7: 885-96. PMID 17139329 DOI: 10.1038/Nrm2066  0.414
2006 Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K, Wang CY, He X, MacDougald OA, You M, Williams BO, et al. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell. 126: 955-68. PMID 16959574 DOI: 10.1016/J.Cell.2006.06.055  0.76
2006 Qiao L, MacDougald OA, Shao J. CCAAT/enhancer-binding protein alpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase. The Journal of Biological Chemistry. 281: 24390-7. PMID 16807249 DOI: 10.1074/Jbc.M603038200  0.346
2006 Xu Y, Zhou YL, Ann DK, MacDougald OA, Shum L, Snead ML. Transcription factor sumoylation and factor YY1 serve to modulate mouse amelogenin gene expression. European Journal of Oral Sciences. 114: 169-77; discussion 2. PMID 16674681 DOI: 10.1111/J.1600-0722.2006.00319.X  0.397
2006 Krishnan V, Bryant HU, Macdougald OA. Regulation of bone mass by Wnt signaling. The Journal of Clinical Investigation. 116: 1202-9. PMID 16670761 DOI: 10.1172/Jci28551  0.393
2006 Xu Y, Zhou YL, Luo W, Zhu QS, Levy D, MacDougald OA, Snead ML. NF-Y and CCAAT/enhancer-binding protein alpha synergistically activate the mouse amelogenin gene. The Journal of Biological Chemistry. 281: 16090-8. PMID 16595692 DOI: 10.1074/Jbc.M510514200  0.387
2006 Hall CL, Kang S, MacDougald OA, Keller ET. Role of Wnts in prostate cancer bone metastases. Journal of Cellular Biochemistry. 97: 661-72. PMID 16447163 DOI: 10.1002/Jcb.20735  0.339
2005 MacDougald OA, Burant CF. Obesity and metabolic perturbations after loss of aquaporin 7, the adipose glycerol transporter. Proceedings of the National Academy of Sciences of the United States of America. 102: 10759-60. PMID 16046537 DOI: 10.1073/Pnas.0504965102  0.34
2005 MacDougald OA, Burant CF. Fickle factor foils fat fate. Nature Cell Biology. 7: 543-5. PMID 15928698 DOI: 10.1038/Ncb0605-543  0.427
2005 Kennell JA, MacDougald OA. Wnt signaling inhibits adipogenesis through beta-catenin-dependent and -independent mechanisms. The Journal of Biological Chemistry. 280: 24004-10. PMID 15849360 DOI: 10.1074/Jbc.M501080200  0.783
2005 Gerin I, Dolinsky VW, Shackman JG, Kennedy RT, Chiang SH, Burant CF, Steffensen KR, Gustafsson JA, MacDougald OA. LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. The Journal of Biological Chemistry. 280: 23024-31. PMID 15831500 DOI: 10.1074/Jbc.M412564200  0.418
2005 Bennett CN, Longo KA, Wright WS, Suva LJ, Lane TF, Hankenson KD, MacDougald OA. Regulation of osteoblastogenesis and bone mass by Wnt10b. Proceedings of the National Academy of Sciences of the United States of America. 102: 3324-9. PMID 15728361 DOI: 10.1073/Pnas.0408742102  0.768
2005 Kang S, Bajnok L, Longo KA, Petersen RK, Hansen JB, Kristiansen K, MacDougald OA. Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha. Molecular and Cellular Biology. 25: 1272-82. PMID 15684380 DOI: 10.1128/Mcb.25.4.1272-1282.2005  0.501
2005 Vertino AM, Taylor-Jones JM, Longo KA, Bearden ED, Lane TF, McGehee RE, MacDougald OA, Peterson CA. Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Molecular Biology of the Cell. 16: 2039-48. PMID 15673614 DOI: 10.1091/Mbc.E04-08-0720  0.393
2004 Longo KA, Wright WS, Kang S, Gerin I, Chiang SH, Lucas PC, Opp MR, MacDougald OA. Wnt10b inhibits development of white and brown adipose tissues. The Journal of Biological Chemistry. 279: 35503-9. PMID 15190075 DOI: 10.1074/Jbc.M402937200  0.434
2004 Ross SE, Radomska HS, Wu B, Zhang P, Winnay JN, Bajnok L, Wright WS, Schaufele F, Tenen DG, MacDougald OA. Phosphorylation of C/EBPalpha inhibits granulopoiesis. Molecular and Cellular Biology. 24: 675-86. PMID 14701740 DOI: 10.1128/Mcb.24.2.675-686.2004  0.624
2003 Kennell JA, O'Leary EE, Gummow BM, Hammer GD, MacDougald OA. T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors. Molecular and Cellular Biology. 23: 5366-75. PMID 12861022 DOI: 10.1128/Mcb.23.15.5366-5375.2003  0.769
2003 Bennett CN, Hodge CL, MacDougald OA, Schwartz J. Role of Wnt10b and C/EBPalpha in spontaneous adipogenesis of 243 cells. Biochemical and Biophysical Research Communications. 302: 12-6. PMID 12593840 DOI: 10.1016/S0006-291X(03)00092-5  0.76
2002 Piwien-Pilipuk G, MacDougald O, Schwartz J. Dual regulation of phosphorylation and dephosphorylation of C/EBPbeta modulate its transcriptional activation and DNA binding in response to growth hormone. The Journal of Biological Chemistry. 277: 44557-65. PMID 12213825 DOI: 10.1074/Jbc.M206886200  0.364
2002 Longo KA, Kennell JA, Ochocinska MJ, Ross SE, Wright WS, MacDougald OA. Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors. The Journal of Biological Chemistry. 277: 38239-44. PMID 12154096 DOI: 10.1074/Jbc.M206402200  0.797
2002 Ross SE, Erickson RL, Gerin I, DeRose PM, Bajnok L, Longo KA, Misek DE, Kuick R, Hanash SM, Atkins KB, Andresen SM, Nebb HI, Madsen L, Kristiansen K, MacDougald OA. Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Molecular and Cellular Biology. 22: 5989-99. PMID 12138207 DOI: 10.1128/Mcb.22.16.5989-5999.2002  0.645
2002 Bennett CN, Ross SE, Longo KA, Bajnok L, Hemati N, Johnson KW, Harrison SD, MacDougald OA. Regulation of Wnt signaling during adipogenesis. The Journal of Biological Chemistry. 277: 30998-1004. PMID 12055200 DOI: 10.1074/Jbc.M204527200  0.805
2002 You Z, Saims D, Chen S, Zhang Z, Guttridge DC, Guan KL, MacDougald OA, Brown AM, Evan G, Kitajewski J, Wang CY. Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis. The Journal of Cell Biology. 157: 429-40. PMID 11980918 DOI: 10.1083/Jcb.200201110  0.394
2002 MacDougald OA, Mandrup S. Adipogenesis: forces that tip the scales. Trends in Endocrinology and Metabolism: Tem. 13: 5-11. PMID 11750856 DOI: 10.1016/S1043-2760(01)00517-3  0.364
2002 Schaufele F, Enwright JF, Wang X, Teoh C, Srihari R, Erickson R, MacDougald OA, Day RN. CCAAT/enhancer binding protein alpha assembles essential cooperating factors in common subnuclear domains. Molecular Endocrinology (Baltimore, Md.). 15: 1665-76. PMID 11579200 DOI: 10.1210/Mend.15.10.0716  0.341
2001 MacDougald OA. Signaling pathway puts the break on fat cell formation. Thescientificworldjournal. 1: 188-9. PMID 12805664 DOI: 10.1100/Tsw.2001.28  0.312
2001 Douglas KR, Brinkmeier ML, Kennell JA, Eswara P, Harrison TA, Patrianakos AI, Sprecher BS, Potok MA, Lyons RH, MacDougald OA, Camper SA. Identification of members of the Wnt signaling pathway in the embryonic pituitary gland. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 843-51. PMID 11845287 DOI: 10.1007/S00335-001-2076-0  0.789
2001 Erickson RL, Hemati N, Ross SE, MacDougald OA. p300 Coactivates the Adipogenic Transcription Factor CCAAT/ Enhancer-binding Protein α Journal of Biological Chemistry. 276: 16348-16355. PMID 11340085 DOI: 10.1074/Jbc.M100128200  0.603
2001 Piwien-Pilipuk G, Van Mater D, Ross SE, MacDougald OA, Schwartz J. Growth hormone regulates phosphorylation and function of CCAAT/enhancer-binding protein beta by modulating Akt and glycogen synthase kinase-3. The Journal of Biological Chemistry. 276: 19664-71. PMID 11278638 DOI: 10.1074/Jbc.M010193200  0.64
2000 Ross SE, Hemati N, Longo KA, Bennett CN, Lucas PC, Erickson RL, MacDougald OA. Inhibition of adipogenesis by Wnt signaling. Science (New York, N.Y.). 289: 950-3. PMID 10937998 DOI: 10.1126/Science.289.5481.950  0.809
2000 Hajra AK, Larkins LK, Das AK, Hemati N, Erickson RL, MacDougald OA. Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes. Role in triacylglycerol synthesis. The Journal of Biological Chemistry. 275: 9441-6. PMID 10734090 DOI: 10.1074/Jbc.275.13.9441  0.337
1999 Ross SE, Erickson RL, Hemati N, MacDougald OA. Glycogen synthase kinase 3 is an insulin-regulated C/EBPα kinase Molecular and Cellular Biology. 19: 8433-8441. PMID 10567568 DOI: 10.1128/Mcb.19.12.8433  0.605
1999 Liao J, Piwien-Pilipuk G, Ross SE, Hodge CL, Sealy L, MacDougald OA, Schwartz J. CCAAT/enhancer-binding protein β (C/EBPβ) and C/EBPδ contribute to growth hormone-regulated transcription of c-fos Journal of Biological Chemistry. 274: 31597-31604. PMID 10531366 DOI: 10.1074/Jbc.274.44.31597  0.623
1999 Becker DJ, MacDougald OA. Transfection of adipocytes by Gene Gun-mediated transfer Biotechniques. 26: 660-668. PMID 10343903 DOI: 10.2144/99264St01  0.407
1998 Darlington GJ, Ross SE, MacDougald OA. The role of C/EBP genes in adipocyte differentiation Journal of Biological Chemistry. 273: 30057-30060. PMID 9804754 DOI: 10.1074/Jbc.273.46.30057  0.606
1998 Hemati N, Erickson RL, Ross SE, Liu R, MacDougald OA. Regulation of CCAAT/enhancer binding proteinα (C/EBPα) gene expression by thiazolidinediones in 3T3-L1 adipocytes Biochemical and Biophysical Research Communications. 244: 20-25. PMID 9514873 DOI: 10.1006/Bbrc.1998.8204  0.635
1997 Hemati N, Ross SE, Erickson RL, Groblewski GE, MacDougald OA. Signaling pathways through which insulin regulates CCAAT/enhancer binding protein (C/EBPα) phosphorylation and gene expression in 3T3-L1 adipocytes. Correlation with GLUT4 gene expression Journal of Biological Chemistry. 272: 25913-25919. PMID 9325324 DOI: 10.1074/Jbc.272.41.25913  0.621
1997 Mandrup S, Loftus TM, MacDougald OA, Kuhajda FP, Lane MD. Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proceedings of the National Academy of Sciences of the United States of America. 94: 4300-5. PMID 9113984 DOI: 10.1073/Pnas.94.9.4300  0.586
1996 Hwang CS, Mandrup S, MacDougald OA, Geiman DE, Lane MD. Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha. Proceedings of the National Academy of Sciences of the United States of America. 93: 873-7. PMID 8570651 DOI: 10.1073/Pnas.93.2.873  0.561
1995 MacDougald OA, Cornelius P, Liu R, Lane MD. Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) alpha, beta, and delta genes in fully-differentiated 3T3-L1 adipocytes. The Journal of Biological Chemistry. 270: 647-54. PMID 7822291 DOI: 10.1074/Jbc.270.2.647  0.576
1995 Potter JJ, MacDougald OA, Mezey E. Regulation of rat alcohol dehydrogenase by cyclic AMP in primary hepatocyte culture. Archives of Biochemistry and Biophysics. 321: 329-35. PMID 7646058 DOI: 10.1006/Abbi.1995.1402  0.349
1995 MacDougald OA, Lane MD. Transcriptional regulation of gene expression during adipocyte differentiation. Annual Review of Biochemistry. 64: 345-73. PMID 7574486 DOI: 10.1146/Annurev.Bi.64.070195.002021  0.606
1995 MacDougald OA, Hwang CS, Fan H, Lane MD. Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proceedings of the National Academy of Sciences of the United States of America. 92: 9034-7. PMID 7568067 DOI: 10.1073/Pnas.92.20.9034  0.603
1995 MacDougald OA, Lane MD. Adipocyte differentiation. When precursors are also regulators. Current Biology : Cb. 5: 618-21. PMID 7552171 DOI: 10.1016/S0960-9822(95)00125-4  0.556
1994 Cornelius P, MacDougald OA, Lane MD. Regulation of adipocyte development. Annual Review of Nutrition. 14: 99-129. PMID 7946535 DOI: 10.1146/Annurev.Nu.14.070194.000531  0.464
1994 Landschulz KT, Jump DB, MacDougald OA, Lane MD. Transcriptional control of the stearoyl-CoA desaturase-1 gene by polyunsaturated fatty acids. Biochemical and Biophysical Research Communications. 200: 763-8. PMID 7910016 DOI: 10.1006/Bbrc.1994.1516  0.688
1993 Lin FT, MacDougald OA, Diehl AM, Lane MD. A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. Proceedings of the National Academy of Sciences of the United States of America. 90: 9606-10. PMID 8415748 DOI: 10.1073/Pnas.90.20.9606  0.525
1993 Jump DB, Clarke SD, MacDougald O, Thelen A. Polyunsaturated fatty acids inhibit S14 gene transcription in rat liver and cultured hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 8454-8. PMID 8378318 DOI: 10.1073/Pnas.90.18.8454  0.625
1993 Jump DB, MacDougald OA. Hormonal Regulation of Gene Expression in Cultured Adipocytes1 Journal of Animal Science. 71: 56-64. DOI: 10.2527/1993.71Supplement_256S  0.609
1992 MacDougald OA, Clarke SD, Jump DB. Tissue specificity of S14 and fatty acid synthase in vitro transcription Biochemical and Biophysical Research Communications. 182: 631-637. PMID 1734874 DOI: 10.1016/0006-291X(92)91779-P  0.605
1992 MacDougald OA, Jump DB. Localization of an adipocyte-specific retinoic acid response domain controlling S14 gene transcription Biochemical and Biophysical Research Communications. 188: 470-476. PMID 1417866 DOI: 10.1016/0006-291X(92)92408-P  0.599
1991 MacDougald OA, Jump DB. Identification of functional cis-acting elements within the rat liver S14 promoter Biochemical Journal. 280: 761-767. PMID 1764039 DOI: 10.1042/Bj2800761  0.613
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