Year |
Citation |
Score |
2019 |
Shukla SD, Restrepo RJ, Aroor AR, Liu X, Lim RW, Franke JD, Ford DA, Korthuis RJ. Binge alcohol is more injurious to liver in female than male rats: histopathological, pharmacological, and epigenetic profiles. The Journal of Pharmacology and Experimental Therapeutics. PMID 31262967 DOI: 10.1124/Jpet.119.258871 |
0.344 |
|
2017 |
Restrepo RJ, Lim RW, Korthuis RJ, Shukla SD. Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation. Alcohol (Fayetteville, N.Y.). PMID 28433418 DOI: 10.1016/J.Alcohol.2017.01.009 |
0.445 |
|
2015 |
Shukla SD, Aroor AR, Restrepo R, Kharbanda KK, Ibdah JA. In Vivo Acute on Chronic Ethanol Effects in Liver: A Mouse Model Exhibiting Exacerbated Injury, Altered Metabolic and Epigenetic Responses. Biomolecules. 5: 3280-94. PMID 26610587 DOI: 10.3390/biom5043280 |
0.49 |
|
2015 |
Shukla SD, Restrepo R, Fish P, Lim RW, Ibdah JA. Different mechanisms for histone acetylation by ethanol and its metabolite acetate in rat primary hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 354: 18-23. PMID 25886906 DOI: 10.1124/Jpet.115.223867 |
0.614 |
|
2014 |
Aroor AR, Restrepo RJ, Kharbanda KK, Shukla SD. Erratum to: Epigenetic histone modifications in a clinically relevant rat model of chronic ethanol-binge-mediated liver injury. Hepatology International. 8: 431. PMID 26201321 DOI: 10.1007/S12072-014-9564-2 |
0.479 |
|
2014 |
Aroor AR, Restrepo RJ, Kharbanda KK, Shukla SD. Epigenetic histone modifications in a clinically relevant rat model of chronic ethanol-binge-mediated liver injury. Hepatology International. 8: 421-30. PMID 26201320 DOI: 10.1007/S12072-014-9546-4 |
0.51 |
|
2013 |
Shukla SD, Lim RW. Epigenetic effects of ethanol on the liver and gastrointestinal system. Alcohol Research : Current Reviews. 35: 47-55. PMID 24313164 |
0.432 |
|
2013 |
Shukla SD, Pruett SB, Szabo G, Arteel GE. Binge ethanol and liver: new molecular developments. Alcoholism, Clinical and Experimental Research. 37: 550-7. PMID 23347137 DOI: 10.1111/Acer.12011 |
0.428 |
|
2012 |
Aroor AR, Roy LJ, Restrepo RJ, Mooney BP, Shukla SD. A proteomic analysis of liver after ethanol binge in chronically ethanol treated rats. Proteome Science. 10: 29. PMID 22545783 DOI: 10.1186/1477-5956-10-29 |
0.524 |
|
2012 |
Park PH, Lim RW, Shukla SD. Gene-selective histone H3 acetylation in the absence of increase in global histone acetylation in liver of rats chronically fed alcohol. Alcohol and Alcoholism (Oxford, Oxfordshire). 47: 233-9. PMID 22301686 DOI: 10.1093/Alcalc/Ags004 |
0.672 |
|
2012 |
Aroor AR, Jackson DE, Shukla SD. Dysregulated phosphorylation and nuclear translocation of cyclic AMP response element binding protein (CREB) in rat liver after chronic ethanol binge. European Journal of Pharmacology. 679: 101-8. PMID 22269225 DOI: 10.1016/J.Ejphar.2011.12.045 |
0.609 |
|
2012 |
James TT, Aroor AR, Lim RW, Shukla SD. Histone H3 phosphorylation (Ser10, Ser28) and phosphoacetylation (K9S10) are differentially associated with gene expression in liver of rats treated in vivo with acute ethanol. The Journal of Pharmacology and Experimental Therapeutics. 340: 237-47. PMID 22025646 DOI: 10.1124/Jpet.111.186775 |
0.811 |
|
2011 |
Aroor AR, Shukla SD. Binge ethanol intake in chronically exposed rat liver decreases LDL-receptor and increases angiotensinogen gene expression. World Journal of Hepatology. 3: 250-5. PMID 21969878 DOI: 10.4254/Wjh.V3.I9.250 |
0.454 |
|
2011 |
Aroor AR, Jackson DE, Shukla SD. Elevated activation of ERK1 and ERK2 accompany enhanced liver injury following alcohol binge in chronically ethanol-fed rats. Alcoholism, Clinical and Experimental Research. 35: 2128-38. PMID 21790671 DOI: 10.1111/J.1530-0277.2011.01577.X |
0.572 |
|
2011 |
Choudhury M, Pandey RS, Clemens DL, Davis JW, Lim RW, Shukla SD. Knock down of GCN5 histone acetyltransferase by siRNA decreases ethanol-induced histone acetylation and affects differential expression of genes in human hepatoma cells. Alcohol (Fayetteville, N.Y.). 45: 311-24. PMID 21367571 DOI: 10.1016/J.Alcohol.2010.12.003 |
0.743 |
|
2011 |
Nichols LA, Jackson DE, Manthey JA, Shukla SD, Holland LJ. Citrus flavonoids repress the mRNA for stearoyl-CoA desaturase, a key enzyme in lipid synthesis and obesity control, in rat primary hepatocytes. Lipids in Health and Disease. 10: 36. PMID 21345233 DOI: 10.1186/1476-511X-10-36 |
0.303 |
|
2010 |
Choudhury M, Park PH, Jackson D, Shukla SD. Evidence for the role of oxidative stress in the acetylation of histone H3 by ethanol in rat hepatocytes. Alcohol (Fayetteville, N.Y.). 44: 531-40. PMID 20705415 DOI: 10.1016/J.Alcohol.2010.06.003 |
0.792 |
|
2010 |
Aroor AR, James TT, Jackson DE, Shukla SD. Differential changes in MAP kinases, histone modifications, and liver injury in rats acutely treated with ethanol. Alcoholism, Clinical and Experimental Research. 34: 1543-51. PMID 20586759 DOI: 10.1111/J.1530-0277.2010.01239.X |
0.816 |
|
2009 |
Aroor AR, Lee YJ, Shukla SD. Activation of MEK 1/2 and p42/44 MAPK by angiotensin II in hepatocyte nucleus and their potentiation by ethanol. Alcohol (Fayetteville, N.Y.). 43: 315-22. PMID 19560630 DOI: 10.1016/J.Alcohol.2009.04.001 |
0.558 |
|
2008 |
Shukla SD, Velazquez J, French SW, Lu SC, Ticku MK, Zakhari S. Emerging role of epigenetics in the actions of alcohol. Alcoholism, Clinical and Experimental Research. 32: 1525-34. PMID 18616668 DOI: 10.1111/J.1530-0277.2008.00729.X |
0.426 |
|
2008 |
Weng YI, Aroor AR, Shukla SD. Ethanol inhibition of angiotensin II-stimulated Tyr705 and Ser727 STAT3 phosphorylation in cultured rat hepatocytes: relevance to activation of p42/44 mitogen-activated protein kinase. Alcohol (Fayetteville, N.Y.). 42: 397-406. PMID 18411006 DOI: 10.1016/J.Alcohol.2008.02.004 |
0.807 |
|
2008 |
Choudhury M, Shukla SD. Surrogate alcohols and their metabolites modify histone H3 acetylation: involvement of histone acetyl transferase and histone deacetylase. Alcoholism, Clinical and Experimental Research. 32: 829-39. PMID 18336638 DOI: 10.1111/J.1530-0277.2008.00630.X |
0.684 |
|
2008 |
Choudhury M, Park PH, Shukla SD. Oxidative stress and ethanol induced histone acetylation in primary rat hepatocytes The Faseb Journal. 22: 632-632. DOI: 10.1096/Fasebj.22.2_Supplement.632 |
0.722 |
|
2007 |
Pal-Bhadra M, Bhadra U, Jackson DE, Mamatha L, Park PH, Shukla SD. Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes. Life Sciences. 81: 979-87. PMID 17826801 DOI: 10.1016/J.Lfs.2007.07.030 |
0.702 |
|
2007 |
Lee YJ, Shukla SD. Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde. European Journal of Pharmacology. 573: 29-38. PMID 17643407 DOI: 10.1016/J.Ejphar.2007.06.049 |
0.62 |
|
2007 |
Shukla SD, Lee YJ, Park PH, Aroor AR. Acetaldehyde alters MAP kinase signalling and epigenetic histone modifications in hepatocytes. Novartis Foundation Symposium. 285: 217-24; discussion 2. PMID 17590997 DOI: 10.1002/9780470511848.Ch16 |
0.745 |
|
2006 |
Shukla SD, Aroor AR. Epigenetic effects of ethanol on liver and gastrointestinal injury. World Journal of Gastroenterology : Wjg. 12: 5265-71. PMID 16981253 DOI: 10.3748/Wjg.V12.I33.5265 |
0.535 |
|
2006 |
Park PH, Aroor AR, Shukla SD. Role of Ras in ethanol modulation of angiotensin II activated p42/p44 MAP kinase in rat hepatocytes. Life Sciences. 79: 2357-63. PMID 16950409 DOI: 10.1016/J.Lfs.2006.07.037 |
0.712 |
|
2006 |
Kim JS, Shukla SD. Acute in vivo effect of ethanol (binge drinking) on histone H3 modifications in rat tissues. Alcohol and Alcoholism (Oxford, Oxfordshire). 41: 126-32. PMID 16314425 DOI: 10.1093/Alcalc/Agh248 |
0.514 |
|
2005 |
Park PH, Lim RW, Shukla SD. Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G1124-36. PMID 16081763 DOI: 10.1152/Ajpgi.00091.2005 |
0.75 |
|
2005 |
Kim JS, Shukla SD. Histone h3 modifications in rat hepatic stellate cells by ethanol. Alcohol and Alcoholism (Oxford, Oxfordshire). 40: 367-72. PMID 15939707 DOI: 10.1093/Alcalc/Agh170 |
0.537 |
|
2005 |
Lee YJ, Shukla SD. Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes. European Journal of Pharmacology. 508: 31-45. PMID 15680252 DOI: 10.1016/J.Ejphar.2004.12.006 |
0.587 |
|
2004 |
Aroor AR, Shukla SD. MAP kinase signaling in diverse effects of ethanol. Life Sciences. 74: 2339-64. PMID 15027449 DOI: 10.1016/J.Lfs.2003.11.001 |
0.614 |
|
2003 |
Park PH, Miller R, Shukla SD. Acetylation of histone H3 at lysine 9 by ethanol in rat hepatocytes. Biochemical and Biophysical Research Communications. 306: 501-4. PMID 12804592 DOI: 10.1016/S0006-291X(03)01040-4 |
0.734 |
|
2003 |
Weng YI, Shukla SD. Effects of chronic ethanol treatment on the angiotensin II-mediated p42/p44 mitogen-activated protein kinase and phosphorylase a activation in rat hepatocytes. Alcohol (Fayetteville, N.Y.). 29: 83-90. PMID 12782249 DOI: 10.1016/S0741-8329(02)00325-7 |
0.811 |
|
2002 |
Aroor AR, Custer GW, Weng YI, Lee YJ, Shukla SD. Phosphotidylethanol mimics ethanol modulation of p42/44 mitogen-activated protein kinase signalling in hepatocytes. Alcohol and Alcoholism (Oxford, Oxfordshire). 37: 534-9. PMID 12414543 DOI: 10.1093/Alcalc/37.6.534 |
0.81 |
|
2002 |
Weng YI, Shukla SD. Angiotensin II activation of focal adhesion kinase and pp60c-Src in relation to mitogen-activated protein kinases in hepatocytes. Biochimica Et Biophysica Acta. 1589: 285-97. PMID 12031795 DOI: 10.1016/S0167-4889(02)00189-1 |
0.75 |
|
2002 |
Lee YJ, Aroor AR, Shukla SD. Temporal activation of p42/44 mitogen-activated protein kinase and c-Jun N-terminal kinase by acetaldehyde in rat hepatocytes and its loss after chronic ethanol exposure. The Journal of Pharmacology and Experimental Therapeutics. 301: 908-14. PMID 12023518 DOI: 10.1124/Jpet.301.3.908 |
0.613 |
|
2001 |
Shukla SD, Sun GY, Gibson Wood W, Savolainen MJ, Alling C, Hoek JB. Ethanol and lipid metabolic signaling. Alcoholism, Clinical and Experimental Research. 25: 33S-39S. PMID 11391046 DOI: 10.1097/00000374-200105051-00006 |
0.498 |
|
2001 |
Magai RM, Shukla SD. Metabolic fate of [14C]-ethanol into endothelial cell phospholipids including platelet-activating factor, sphingomyelin and phosphatidylethanol. Journal of Biomedical Science. 8: 143-50. PMID 11173988 DOI: 10.1007/Bf02255983 |
0.555 |
|
2001 |
Hillen TJ, Aroor AR, Shukla SD. Selective secretion of protein kinase C isozymes by thrombin-stimulated human platelets. Biochemical and Biophysical Research Communications. 280: 259-64. PMID 11162508 DOI: 10.1006/Bbrc.2000.4083 |
0.383 |
|
2001 |
Magai RM, Shukla SD. Metabolic Fate of [14C]-Ethanol into Endothelial Cell Phospholipids Including Platelet-Activating Factor, Sphingomyelin and Phosphatidylethanol Journal of Biomedical Science. 8: 143-150. DOI: 10.1159/000054025 |
0.331 |
|
2001 |
Shukla SD, Sun GY, Gibson Wood W, Savolainen MJ, Alling C, Hoek JB. Ethanol and Lipid Metabolic Signaling Alcoholism: Clinical and Experimental Research. 25: 33S-39S. DOI: 10.1111/J.1530-0277.2001.TB02370.X |
0.314 |
|
2000 |
Reddy MA, Shukla SD. Nuclear activation and translocation of mitogen-activated protein kinases modulated by ethanol in embryonic liver cells. Biochimica Et Biophysica Acta. 1497: 271-8. PMID 10903432 DOI: 10.1016/S0167-4889(00)00058-6 |
0.602 |
|
2000 |
Weng Y, Shukla SD. Ethanol alters angiotensin II stimulated mitogen activated protein kinase in hepatocytes: agonist selectivity and ethanol metabolic independence. European Journal of Pharmacology. 398: 323-31. PMID 10862821 DOI: 10.1016/S0014-2999(00)00313-7 |
0.818 |
|
1999 |
Kansra SV, Reddy MA, Weng YI, Shukla SD. Activation of mitogen activated protein kinase in human platelets by genistein. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 39: 21-31. PMID 10051374 DOI: 10.1006/Phrs.1998.0402 |
0.755 |
|
1998 |
Tripathi YB, Shukla SD. Rubia cordifolia extract inhibits cell proliferation in A-431 cells Phytotherapy Research. 12: 454-456. DOI: 10.1002/(Sici)1099-1573(199809)12:6<454::Aid-Ptr331>3.0.Co;2-N |
0.309 |
|
1996 |
Shukla SD. Tyrosine kinase activation by PAF leads to downstream gene expression. Advances in Experimental Medicine and Biology. 416: 153-5. PMID 9131141 DOI: 10.1007/978-1-4899-0179-8_25 |
0.372 |
|
1996 |
Halenda SP, Wu H, Jones AW, Shukla SD. Phospholipase D in platelets and megakaryocytic cells. Chemistry and Physics of Lipids. 80: 21-6. PMID 8681425 DOI: 10.1016/0009-3084(96)02542-X |
0.306 |
|
1996 |
Reddy MA, Shukla SD. Potentiation of mitogen-activated protein kinase by ethanol in embryonic liver cells. Biochemical Pharmacology. 51: 661-8. PMID 8615903 DOI: 10.1016/S0006-2952(95)02239-2 |
0.597 |
|
1993 |
Jones AW, Shukla SD, Geisbuhler BB. Stimulation of phospholipase D activity and phosphatidic acid production by norepinephrine in rat aorta. The American Journal of Physiology. 264: C609-16. PMID 8460667 DOI: 10.1152/Ajpcell.1993.264.3.C609 |
0.329 |
|
1993 |
Dhar A, Shukla SD. Tyrosine kinases in platelet signalling. British Journal of Haematology. 84: 1-7. PMID 8338765 DOI: 10.1111/J.1365-2141.1993.Tb03018.X |
0.33 |
|
1993 |
Zhu CY, Shukla SD. Increased tyrosine kinase activity in pp60c-src immunoprecipitate from platelet activating factor stimulated human platelets: in vitro phosphorylation of a synthetic peptide. Life Sciences. 53: 175-83. PMID 7685849 DOI: 10.1016/0024-3205(93)90665-P |
0.373 |
|
1992 |
Tripathi YB, Lim RW, Fernandez-Gallardo S, Kandala JC, Guntaka RV, Shukla SD. Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells. The Biochemical Journal. 286: 527-33. PMID 1382409 DOI: 10.1042/Bj2860527 |
0.4 |
|
1992 |
Thurston AW, Shukla SD. Ethanol modulates epidermal growth factor-stimulated tyrosine kinase and phosphorylation of PLC-gamma 1. Biochemical and Biophysical Research Communications. 185: 1062-8. PMID 1320873 DOI: 10.1016/0006-291X(92)91734-8 |
0.548 |
|
1992 |
Shukla SD. Platelet-activating factor receptor and signal transduction mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 2296-301. PMID 1312046 DOI: 10.1096/Fasebj.6.6.1312046 |
0.347 |
|
1991 |
Shukla SD, Halenda SP. Phospholipase D in cell signalling and its relationship to phospholipase C. Life Sciences. 48: 851-66. PMID 1997787 DOI: 10.1016/0024-3205(91)90031-6 |
0.333 |
|
1991 |
Shukla SD. Inositol phospholipid turnover in PAF transmembrane signalling. Lipids. 26: 1028-33. PMID 1668102 DOI: 10.1007/Bf02536496 |
0.337 |
|
1989 |
Morrison WJ, Dhar A, Shukla SD. Staurosporine potentiates platelet activating factor stimulated phospholipase C activity in rabbit platelets but does not block desensitization by platelet activating factor. Life Sciences. 45: 333-9. PMID 2761347 DOI: 10.1016/0024-3205(89)90143-4 |
0.413 |
|
1987 |
Shukla SD, Franklin CC, Carter MG. Activation of phospholipase C in platelets by platelet activating factor and thrombin causes hydrolysis of a common pool of phosphatidylinositol 4,5-bisphosphate. Biochimica Et Biophysica Acta. 929: 134-41. PMID 3036249 DOI: 10.1016/0167-4889(87)90168-6 |
0.337 |
|
1985 |
Shukla SD. Platelet activating factor-stimulated formation of inositol triphosphate in platelets and its regulation by various agents including Ca2+, indomethacin, CV-3988, and forskolin. Archives of Biochemistry and Biophysics. 240: 674-81. PMID 3875314 DOI: 10.1016/0003-9861(85)90075-X |
0.321 |
|
1985 |
Shukla SD, Sergeant S, Kim HD. [3H]Inositol incorporation into phosphoinositides of pig reticulocytes. Biochimica Et Biophysica Acta. 821: 305-9. PMID 2998471 DOI: 10.1016/0005-2736(85)90100-2 |
0.314 |
|
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