Kim Boekelheide - Publications

Affiliations: 
Brown University, Providence, RI 
Area:
Cell Biology, Pathology, Molecular Biology

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Stermer AR, Wilson SK, Klein D, Hall SJ, Boekelheide K. Trichloroethylene exposure alters dimethylated histone three lysine four in protein kinase A signaling pathway chromatin of rat sperm. Biology of Reproduction. PMID 31426087 DOI: 10.1093/Biolre/Ioz155  0.325
2019 Spade DJ, Bai CY, Lambright C, Conley JM, Boekelheide K, Gray LE. Corrigendum to "Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells" [Toxicol. Lett. 290 (2018) 55-61]. Toxicology Letters. PMID 31253470 DOI: 10.1016/J.Toxlet.2019.06.001  0.411
2019 Dent MP, Madnick SJ, Hall S, Policelli MV, Bars C, Li H, Amin A, Carmichael PL, Martin FL, Boekelheide K. A human-derived prostate co-culture microtissue model using epithelial (RWPE-1) and stromal (WPMY-1) cell lines. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 31154061 DOI: 10.1016/J.Tiv.2019.05.023  0.342
2019 Stermer AR, Klein D, Wilson SK, Dalaijamts C, Bai CY, Hall SJ, Madnick S, Bianchi E, Chiu WA, Boekelheide K. Differential toxicity of water versus gavage exposure to trichloroethylene in rats. Environmental Toxicology and Pharmacology. 68: 1-3. PMID 30836291 DOI: 10.1016/J.Etap.2019.02.003  0.303
2018 Spade DJ, Hall SJ, Wortzel JD, Reyes G, Boekelheide K. All-trans retinoic acid disrupts development in ex vivo cultured fetal rat testes. II: Modulation of mono-(2-ethylhexyl) phthalate toxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30476341 DOI: 10.1093/Toxsci/Kfy283  0.412
2018 Spade DJ, Dere E, Hall SJ, Schorl C, Freiman RN, Boekelheide K. All-trans retinoic acid disrupts development in ex vivo cultured fetal rat testes. I: Altered seminiferous cord maturation and testicular cell fate. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30329139 DOI: 10.1093/Toxsci/Kfy260  0.376
2018 Dere E, Anderson LM, Huse SM, Spade DJ, McDonnell-Clark E, Madnick SJ, Hall SJ, Camacho L, Lewis SM, Vanlandingham MM, Boekelheide K. Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study. Toxicology and Applied Pharmacology. PMID 29596923 DOI: 10.1016/J.Taap.2018.03.021  0.349
2018 Spade DJ, Bai CY, Lambright C, Conley JM, Boekelheide K, Gray LE. Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells. Toxicology Letters. PMID 29571896 DOI: 10.1016/J.Toxlet.2018.03.018  0.35
2018 Wilson S, Dere E, Klein D, Schorl C, Hall S, Boekelheide K. Localization of dimethylated histone three lysine four in the Rattus norvegicus sperm genome. Biology of Reproduction. PMID 29506216 DOI: 10.1093/Biolre/Ioy051  0.328
2017 Dai MS, Hall SJ, Vantangoli Policelli MM, Boekelheide K, Spade DJ. Spontaneous testicular atrophy occurs despite normal spermatogonial proliferation in a Tp53 knockout rat. Andrology. PMID 28834365 DOI: 10.1111/Andr.12409  0.379
2017 Bianchi E, Boekelheide K, Sigman M, Hall SJ, Hwang K. Ghrelin modulates testicular damage in a cryptorchid mouse model. Plos One. 12: e0177995. PMID 28542403 DOI: 10.1371/Journal.Pone.0177995  0.421
2017 Dere E, Spade DJ, Hall SJ, Altemus A, Smith JD, Phillips JA, Moffit JS, Blanchard KT, Boekelheide K. Identification of sperm mRNA biomarkers associated with testis injury during preclinical testing of pharmaceutical compounds. Toxicology and Applied Pharmacology. PMID 28167222 DOI: 10.1016/J.Taap.2017.02.001  0.352
2016 Pendse SN, Maertens A, Rosenberg M, Roy D, Fasani RA, Vantangoli MM, Madnick SJ, Boekelheide K, Fornace AJ, Odwin SA, Yager JD, Hartung T, Andersen ME, McMullen PD. Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity. Archives of Toxicology. PMID 27592001 DOI: 10.1007/S00204-016-1824-6  0.331
2016 Dere E, Wilson S, Anderson L, Boekelheide K. Sperm Molecular Biomarkers Are Sensitive Indicators of Testicular Injury Following Subchronic Model Toxicant Exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27466211 DOI: 10.1093/Toxsci/Kfw137  0.375
2016 Kleensang A, Vantangoli MM, Odwin-DaCosta S, Andersen ME, Boekelheide K, Bouhifd M, Fornace AJ, Li HH, Livi CB, Madnick S, Maertens A, Rosenberg M, Yager JD, Zhaog L, Hartung T. Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function. Scientific Reports. 6: 28994. PMID 27456714 DOI: 10.1038/Srep28994  0.413
2016 Vantangoli MM, Madnick SJ, Wilson S, Boekelheide K. Estradiol Exposure Differentially Alters Monolayer versus Microtissue MCF-7 Human Breast Carcinoma Cultures. Plos One. 11: e0157997. PMID 27379522 DOI: 10.1371/Journal.Pone.0157997  0.317
2016 Vantangoli MM, Wilson S, Madnick SJ, Huse SM, Boekelheide K. Morphologic Effects of Estrogen Stimulation on 3D MCF-7 Microtissues. Toxicology Letters. PMID 26921789 DOI: 10.1016/J.Toxlet.2016.02.012  0.362
2016 Dent M, Carmichael P, Vantangoli M, Boekelheide K, Martin FL. Overcoming barriers to non-animal risk assessments for anti-androgenic effects in humans Toxicology Letters. 258. DOI: 10.1016/J.Toxlet.2016.06.1592  0.33
2015 Spade DJ, Hall SJ, Wilson S, Boekelheide K. Di-n-Butyl Phthalate Induces Multinucleated Germ Cells in the Rat Fetal Testis Through a Non-Proliferative Mechanism. Biology of Reproduction. PMID 26400400 DOI: 10.1095/Biolreprod.115.131615  0.353
2015 Vantangoli MM, Madnick SJ, Huse SM, Weston P, Boekelheide K. MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels. Plos One. 10: e0135426. PMID 26267486 DOI: 10.1371/Journal.Pone.0135426  0.311
2015 Curran S, Vantangoli MM, Boekelheide K, Morgan JR. Architecture of Chimeric Spheroids Controls Drug Transport. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 8: 101-9. PMID 26239082 DOI: 10.1007/S12307-015-0171-0  0.408
2015 Saffarini CM, McDonnell-Clark EV, Amin A, Huse SM, Boekelheide K. Developmental exposure to estrogen alters differentiation and epigenetic programming in a human fetal prostate xenograft model. Plos One. 10: e0122290. PMID 25799167 DOI: 10.1371/Journal.Pone.0122290  0.307
2014 Catlin NR, Huse SM, Boekelheide K. The stage-specific testicular germ cell apoptotic response to low-dose X-irradiation and 2,5-hexanedione combined exposure. I: Validation of the laser capture microdissection method for qRT-PCR array application. Toxicologic Pathology. 42: 1221-8. PMID 24717900 DOI: 10.1177/0192623314526319  0.308
2014 Catlin NR, Huse SM, Boekelheide K. The stage-specific testicular germ cell apoptotic response to low-dose radiation and 2,5-hexanedione combined exposure. II: qRT-PCR array analysis reveals dose dependent adaptive alterations in the apoptotic pathway. Toxicologic Pathology. 42: 1229-37. PMID 24670816 DOI: 10.1177/0192623314525689  0.393
2014 Spade DJ, Hall SJ, Saffarini CM, Huse SM, McDonnell EV, Boekelheide K. Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay. Toxicological Sciences : An Official Journal of the Society of Toxicology. 138: 148-60. PMID 24284787 DOI: 10.1093/Toxsci/Kft266  0.358
2013 Chapin RE, Boekelheide K, Cortvrindt R, van Duursen MB, Gant T, Jegou B, Marczylo E, van Pelt AM, Post JN, Roelofs MJ, Schlatt S, Teerds KJ, Toppari J, Piersma AH. Assuring safety without animal testing: the case for the human testis in vitro. Reproductive Toxicology (Elmsford, N.Y.). 39: 63-8. PMID 23612449 DOI: 10.1016/J.Reprotox.2013.04.004  0.329
2012 Springer C, Dere E, Hall SJ, McDonnell EV, Roberts SC, Butt CM, Stapleton HM, Watkins DJ, McClean MD, Webster TF, Schlezinger JJ, Boekelheide K. Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dust. Environmental Health Perspectives. 120: 1711-9. PMID 23014847 DOI: 10.1289/Ehp.1204932  0.381
2012 Pacheco SE, Anderson LM, Sandrof MA, Vantangoli MM, Hall SJ, Boekelheide K. Sperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat. Plos One. 7: e44280. PMID 22952946 DOI: 10.1371/Journal.Pone.0044280  0.361
2012 Campion S, Catlin N, Heger N, McDonnell EV, Pacheco SE, Saffarini C, Sandrof MA, Boekelheide K. Male reprotoxicity and endocrine disruption. Exs. 101: 315-60. PMID 22945574 DOI: 10.1007/978-3-7643-8340-4_11  0.324
2012 Johnson KJ, Heger NE, Boekelheide K. Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 235-48. PMID 22700540 DOI: 10.1093/Toxsci/Kfs206  0.367
2012 Heger NE, Hall SJ, Sandrof MA, McDonnell EV, Hensley JB, McDowell EN, Martin KA, Gaido KW, Johnson KJ, Boekelheide K. Human fetal testis xenografts are resistant to phthalate-induced endocrine disruption. Environmental Health Perspectives. 120: 1137-43. PMID 22511013 DOI: 10.1289/Ehp.1104711  0.412
2012 Campion SN, Catlin N, Houseman EA, Hensley J, Sui Y, Gaido KW, Wu Z, Boekelheide K. Molecular alterations underlying the enhanced disruption of spermatogenesis by 2,5-hexanedione and carbendazim co-exposure. Reproductive Toxicology (Elmsford, N.Y.). 33: 382-9. PMID 22382377 DOI: 10.1016/J.Reprotox.2012.01.014  0.301
2012 Saffarini CM, Heger NE, Yamasaki H, Liu T, Hall SJ, Boekelheide K. Induction and persistence of abnormal testicular germ cells following gestational exposure to di-(n-butyl) phthalate in p53-null mice. Journal of Andrology. 33: 505-13. PMID 21868749 DOI: 10.2164/Jandrol.111.013706  0.414
2011 Bhattacharya S, Zhang Q, Carmichael PL, Boekelheide K, Andersen ME. Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways. Plos One. 6: e20887. PMID 21701582 DOI: 10.1371/Journal.Pone.0020887  0.323
2011 Thanos CG, Bintz BE, Goddard M, Boekelheide K, Hall S, Emerich DF. Functional modulation of choroid plexus epithelial clusters in vitro for tissue repair applications. Cell Transplantation. 20: 1659-72. PMID 21396169 DOI: 10.3727/096368911X564985  0.345
2010 Campion SN, Houseman EA, Sandrof MA, Hensley JB, Sui Y, Gaido KW, Wu Z, Boekelheide K. Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. II. Gene array analysis reveals adaptive changes in cell cycle and cell death pathways. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 457-65. PMID 20616210 DOI: 10.1093/Toxsci/Kfq204  0.45
2010 Yamasaki H, Sandrof MA, Boekelheide K. Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. I. Histopathological analysis reveals stage dependence of attenuated apoptosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 449-56. PMID 20616207 DOI: 10.1093/Toxsci/Kfq203  0.451
2010 Campion SN, Sandrof MA, Yamasaki H, Boekelheide K. Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. III. Candidate gene analysis identifies a role for fas in the attenuation of X-ray-induced apoptosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 466-74. PMID 20616204 DOI: 10.1093/Toxsci/Kfq205  0.448
2010 Krewski D, Acosta D, Andersen M, Anderson H, Bailar JC, Boekelheide K, Brent R, Charnley G, Cheung VG, Green S, Kelsey KT, Kerkvliet NI, Li AA, McCray L, Meyer O, et al. Toxicity testing in the 21st century: a vision and a strategy. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 51-138. PMID 20574894 DOI: 10.1080/10937404.2010.483176  0.318
2010 Boekelheide K, Campion SN. Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 20-4. PMID 20026472 DOI: 10.1093/Toxsci/Kfp307  0.305
2009 Boekelheide K, Kleymenova E, Liu K, Swanson C, Gaido KW. Dose-dependent effects on cell proliferation, seminiferous tubules, and male germ cells in the fetal rat testis following exposure to di(n-butyl) phthalate. Microscopy Research and Technique. 72: 629-38. PMID 19165735 DOI: 10.1002/Jemt.20684  0.46
2009 Paul E, Cronan R, Weston PJ, Boekelheide K, Sedivy JM, Lee SY, Wiest DL, Resnick MB, Klysik JE. Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 92-108. PMID 19145458 DOI: 10.1007/S00335-008-9168-Z  0.347
2008 Bryant BH, Yamasaki H, Sandrof MA, Boekelheide K. Spermatid head retention as a marker of 2,5-hexanedione-induced testicular toxicity in the rat. Toxicologic Pathology. 36: 552-9. PMID 18467684 DOI: 10.1177/0192623308317426  0.376
2008 Ryu KY, Sinnar SA, Reinholdt LG, Vaccari S, Hall S, Garcia MA, Zaitseva TS, Bouley DM, Boekelheide K, Handel MA, Conti M, Kopito RR. The mouse polyubiquitin gene Ubb is essential for meiotic progression. Molecular and Cellular Biology. 28: 1136-46. PMID 18070917 DOI: 10.1128/Mcb.01566-07  0.352
2007 Moffit JS, Bryant BH, Hall SJ, Boekelheide K. Dose-dependent effects of sertoli cell toxicants 2,5-hexanedione, carbendazim, and mono-(2-ethylhexyl) phthalate in adult rat testis. Toxicologic Pathology. 35: 719-27. PMID 17763286 DOI: 10.1080/01926230701481931  0.479
2007 Bryant BH, Boekelheide K. Time-dependent changes in post-mortem testis histopathology in the rat. Toxicologic Pathology. 35: 665-71. PMID 17676525 DOI: 10.1080/01926230701459994  0.397
2007 Moffit JS, Boekelheide K, Sedivy JM, Klysik J. Mice lacking Raf kinase inhibitor protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury. Journal of Andrology. 28: 883-90. PMID 17554109 DOI: 10.2164/Jandrol.107.002964  0.422
2007 Gaido KW, Hensley JB, Liu D, Wallace DG, Borghoff S, Johnson KJ, Hall SJ, Boekelheide K. Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 491-503. PMID 17361019 DOI: 10.1093/Toxsci/Kfm049  0.337
2007 Rasoulpour RJ, Boekelheide K. NF-kappaB activation elicited by ionizing radiation is proapoptotic in testis. Biology of Reproduction. 76: 279-85. PMID 17123945 DOI: 10.1095/Biolreprod.106.054924  0.668
2006 Rasoulpour RJ, Boekelheide K. The Sycp1-Cre transgenic mouse and male germ cell inhibition of NF-kappa b. Journal of Andrology. 27: 729-33. PMID 16775250 DOI: 10.2164/Jandrol.106.000950  0.73
2005 Beall SA, Boekelheide K, Johnson KJ. Hybrid GPCR/cadherin (Celsr) proteins in rat testis are expressed with cell type specificity and exhibit differential Sertoli cell-germ cell adhesion activity. Journal of Andrology. 26: 529-38. PMID 15955893 DOI: 10.2164/Jandrol.05003  0.783
2005 Kleymenova E, Swanson C, Boekelheide K, Gaido KW. Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact. Biology of Reproduction. 73: 482-90. PMID 15901642 DOI: 10.1095/Biolreprod.104.037184  0.447
2005 Boekelheide K. Mechanisms of toxic damage to spermatogenesis. Journal of the National Cancer Institute. Monographs. 6-8. PMID 15784812 DOI: 10.1093/Jncimonographs/Lgi006  0.462
2005 Boekelheide K, Schoenfeld HA, Hall SJ, Weng CC, Shetty G, Leith J, Harper J, Sigman M, Hess DL, Meistrich ML. Gonadotropin-releasing hormone antagonist (Cetrorelix) therapy fails to protect nonhuman primates (Macaca arctoides) from radiation-induced spermatogenic failure. Journal of Andrology. 26: 222-34. PMID 15713828 DOI: 10.1002/J.1939-4640.2005.Tb01089.X  0.307
2005 Rasoulpour RJ, Boekelheide K. NF-kappaB is activated in the rat testis following exposure to mono-(2-ethylhexyl) phthalate. Biology of Reproduction. 72: 479-86. PMID 15496515 DOI: 10.1095/Biolreprod.104.034363  0.706
2005 Augustine LM, Markelewicz RJ, Boekelheide K, Cherrington NJ. Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 182-9. PMID 15494472 DOI: 10.1124/Dmd.104.001024  0.336
2005 Boekelheide K, Johnson KJ, Richburg JH. Sertoli Cell Toxicants Sertoli Cell Biology. 345-382. DOI: 10.1016/B978-012647751-1/50021-0  0.726
2004 Boekelheide K. Cracking the nut. Toxicological Sciences : An Official Journal of the Society of Toxicology. 81: 1-2. PMID 15384182 DOI: 10.1093/Toxsci/Kfh196  0.348
2004 Markelewicz RJ, Hall SJ, Boekelheide K. 2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 92-100. PMID 15141104 DOI: 10.1093/Toxsci/Kfh140  0.393
2003 Rasoulpour RJ, Schoenfeld HA, Gray DA, Boekelheide K. Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging. The American Journal of Pathology. 163: 2595-603. PMID 14633631 DOI: 10.1016/S0002-9440(10)63614-0  0.698
2003 Hixon ML, Boekelheide K. Expression and localization of total Akt1 and phosphorylated Akt1 in the rat seminiferous epithelium. Journal of Andrology. 24: 891-8. PMID 14581516 DOI: 10.1002/J.1939-4640.2003.Tb03141.X  0.444
2003 Fleming SL, Shank PR, Boekelheide K. gamma-Tubulin overexpression in Sertoli cells in vivo: I. Localization to sites of spermatid head attachment and alterations in Sertoli cell microtubule distribution. Biology of Reproduction. 69: 310-21. PMID 12672673 DOI: 10.1095/Biolreprod.102.011791  0.795
2003 Fleming SL, Shank PR, Boekelheide K. gamma-Tubulin overexpression in Sertoli cells in vivo. II: Retention of spermatids, residual bodies, and germ cell apoptosis. Biology of Reproduction. 69: 322-30. PMID 12672672 DOI: 10.1095/Biolreprod.102.011817  0.807
2003 McBurney MW, Yang X, Jardine K, Hixon M, Boekelheide K, Webb JR, Lansdorp PM, Lemieux M. The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis. Molecular and Cellular Biology. 23: 38-54. PMID 12482959 DOI: 10.1128/Mcb.23.1.38-54.2003  0.303
2003 Boekelheide K, Fleming SL, Allio T, Embree-Ku ME, Hall SJ, Johnson KJ, Kwon EJ, Patel SR, Rasoulpour RJ, Schoenfeld HA, Thompson S. 2,5-hexanedione-induced testicular injury. Annual Review of Pharmacology and Toxicology. 43: 125-47. PMID 12471174 DOI: 10.1146/Annurev.Pharmtox.43.100901.135930  0.766
2002 Embree-Ku M, Boekelheide K. FasL deficiency enhances the development of tumors in p53+/- mice. Toxicologic Pathology. 30: 705-13. PMID 12512872 DOI: 10.1080/01926230290166797  0.311
2002 Embree-Ku M, Boekelheide K. Absence of p53 and FasL has sexually dimorphic effects on both development and reproduction. Experimental Biology and Medicine (Maywood, N.J.). 227: 545-53. PMID 12094020 DOI: 10.1177/153537020222700720  0.324
2002 Embree-Ku M, Venturini D, Boekelheide K. Fas is involved in the p53-dependent apoptotic response to ionizing radiation in mouse testis. Biology of Reproduction. 66: 1456-61. PMID 11967210 DOI: 10.1095/Biolreprod66.5.1456  0.4
2002 Johnson KJ, Boekelheide K. Dynamic testicular adhesion junctions are immunologically unique. II. Localization of classic cadherins in rat testis. Biology of Reproduction. 66: 992-1000. PMID 11906918 DOI: 10.1095/Biolreprod66.4.992  0.414
2002 Johnson KJ, Boekelheide K. Dynamic testicular adhesion junctions are immunologically unique. I. Localization of p120 catenin in rat testis. Biology of Reproduction. 66: 983-91. PMID 11906917 DOI: 10.1095/Biolreprod66.4.983  0.32
2001 Boekelheide K, Schoenfeld HA. Spermatogenesis by Sisyphus: proliferating stem germ cells fail to repopulate the testis after 'irreversible' injury. Advances in Experimental Medicine and Biology. 500: 421-8. PMID 11764975 DOI: 10.1007/978-1-4615-0667-6_64  0.507
2001 Schoenfeld HA, Hall SJ, Boekelheide K. Continuously proliferative stem germ cells partially repopulate the aged, atrophic rat testis after gonadotropin-releasing hormone agonist therapy. Biology of Reproduction. 64: 1273-82. PMID 11259276 DOI: 10.1095/Biolreprod64.4.1273  0.359
2000 Richburg JH, Nan Ez A, Williams LR, Embree ME, Boekelheide K. Sensitivity of Testicular Germ Cells to Toxicant-Induced Apoptosis in gld Mice That Express a Nonfunctional Form of Fas Ligand1. Endocrinology. 141: 787-793. PMID 28201080 DOI: 10.1210/endo.141.2.7325  0.751
2000 Boekelheide K, Fleming SL, Johnson KJ, Patel SR, Schoenfeld HA. Role of Sertoli cells in injury-associated testicular germ cell apoptosis. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 225: 105-15. PMID 11044252 DOI: 10.1111/J.1525-1373.2000.22513.X  0.816
2000 Richburg JH, Nañez A, Williams LR, Embree ME, Boekelheide K. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. 141: 787-93. PMID 10650961 DOI: 10.1210/Endo.141.2.7325  0.772
2000 Johnson KJ, Patel SR, Boekelheide K. Multiple cadherin superfamily members with unique expression profiles are produced in rat testis. Endocrinology. 141: 675-83. PMID 10650949 DOI: 10.1210/Endo.141.2.7334  0.416
2000 Fox RA, Sigman M, Boekelheide K. Transmembrane versus soluble stem cell factor expression in human testis. Journal of Andrology. 21: 579-585. DOI: 10.1002/J.1939-4640.2000.Tb02123.X  0.402
1999 Lee J, Richburg JH, Shipp EB, Meistrich ML, Boekelheide K. The Fas system, a regulator of testicular germ cell apoptosis, is differentially up-regulated in Sertoli cell versus germ cell injury of the testis. Endocrinology. 140: 852-8. PMID 9927315 DOI: 10.1210/Endo.140.2.6479  0.773
1999 Varmuza S, Jurisicova A, Okano K, Hudson J, Boekelheide K, Shipp EB. Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene. Developmental Biology. 205: 98-110. PMID 9882500 DOI: 10.1006/Dbio.1998.9100  0.357
1998 Boekelheide K, Lee J, Shipp EB, Richburg JH, Li G. Expression of Fas system-related genes in the testis during development and after toxicant exposure. Toxicology Letters. 102: 503-8. PMID 10022303 DOI: 10.1016/S0378-4274(98)00242-2  0.747
1998 Blanchard KT, Lee J, Boekelheide K. Leuprolide, a gonadotropin-releasing hormone agonist, reestablishes spermatogenesis after 2,5-hexanedione-induced irreversible testicular injury in the rat, resulting in normalized stem cell factor expression. Endocrinology. 139: 236-44. PMID 9421420 DOI: 10.1210/Endo.139.1.5678  0.391
1998 Lee J, Richburg J, Li G, Boekelheide K. Molecular and genetic aspects of toxicant-induced apoptosis in the male germ line Toxicology Letters. 95: 25. DOI: 10.1016/S0378-4274(98)80097-0  0.647
1998 Lee J, Richburg JH, Younkin SC, Boekelheide K. The fas system is a key regulator of germ cell apoptosis in the testis Journal of Urology. 160: 623. DOI: 10.1016/S0022-5347(01)62980-X  0.739
1997 Blanchard KT, Boekelheide K. Adenovirus-mediated gene transfer to rat testis in vivo. Biology of Reproduction. 56: 495-500. PMID 9116152 DOI: 10.1095/Biolreprod56.2.495  0.444
1997 Lee J, Richburg JH, Younkin SC, Boekelheide K. The Fas system is a key regulator of germ cell apoptosis in the testis. Endocrinology. 138: 2081-8. PMID 9112408 DOI: 10.1210/Endo.138.5.5110  0.768
1997 Costa SL, Boekelheide K, Vanderhyden BC, Seth R, McBurney MW. Male infertility caused by epididymal dysfunction in transgenic mice expressing a dominant negative mutation of retinoic acid receptor alpha 1. Biology of Reproduction. 56: 985-90. PMID 9096882 DOI: 10.1095/Biolreprod56.4.985  0.327
1997 Jiang C, Hall SJ, Boekelheide K. Cloning and characterization of the 5' flanking region of the stem cell factor gene in rat Sertoli cells Gene. 185: 285-290. PMID 9055828 DOI: 10.1016/S0378-1119(96)00668-3  0.381
1997 Allard EK, Blanchard KT, Boekelheide K. Exogenous stem cell factor (SCF) compensates for altered endogenous SCF expression in 2,5-hexanedione-induced testicular atrophy in rats. Biology of Reproduction. 55: 185-93. PMID 8793074 DOI: 10.1095/Biolreprod55.1.185  0.506
1997 Jiang C, Hall SJ, Boekelheide K. Development and Characterization of a Prepubertal Rat Sertoli Cell Line, 93RS2 Journal of Andrology. 18: 393-399. DOI: 10.1002/J.1939-4640.1997.Tb01944.X  0.444
1996 Allard EK, Boekelheide K. Fate of germ cells in 2,5-hexanedione-induced testicular injury. II. Atrophy persists due to a reduced stem cell mass and ongoing apoptosis. Toxicology and Applied Pharmacology. 137: 149-56. PMID 8848794 DOI: 10.1006/Taap.1996.0067  0.507
1996 Blanchard KT, Allard EK, Boekelheide K. Fate of germ cells in 2,5-hexanedione-induced testicular injury. I. Apoptosis is the mechanism of germ cell death. Toxicology and Applied Pharmacology. 137: 141-8. PMID 8661338 DOI: 10.1006/Taap.1996.0066  0.519
1996 Richburg JH, Boekelheide K. Mono-(2-ethylhexyl) phthalate rapidly alters both Sertoli cell vimentin filaments and germ cell apoptosis in young rat testes Toxicology and Applied Pharmacology. 137: 42-50. PMID 8607140 DOI: 10.1006/Taap.1996.0055  0.759
1996 Redenbach DM, Hall ES, Boekelheide K. Distribution of Sertoli cell microtubules, microtubule-dependent motors, and the Golgi apparatus before and after tight junction formation in developing rat testis. Microscopy Research and Technique. 32: 504-19. PMID 8605398 DOI: 10.1002/Jemt.1070320604  0.429
1995 Hall ES, Hall SJ, Boekelheide K. 2,5-Hexanedione exposure alters microtubule motor distribution in adult rat testis. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 24: 173-82. PMID 7737429 DOI: 10.1006/Faat.1995.1021  0.435
1995 Allard EK, Hall SJ, Boekelheide K. Stem cell kinetics in rat testis after irreversible injury induced by 2,5- hexanedione Biology of Reproduction. 53: 186-192. PMID 7669848 DOI: 10.1095/Biolreprod53.1.186  0.421
1994 Redenbach DM, Richburg JH, Boekelheide K. Microtubules with altered assembly kinetics have a decreased rate of kinesin-based transport Cell Motility and the Cytoskeleton. 27: 79-87. PMID 8194112 DOI: 10.1002/Cm.970270109  0.647
1994 McBurney MW, Staines WA, Boekelheide K, Parry D, Jardine K, Pickavance L. Murine Pgk-1 promoter drives widespread but not uniform expression in transgenic mice Developmental Dynamics. 200: 278-293. PMID 7994075 DOI: 10.1002/Aja.1002000403  0.418
1994 Richburg JH, Redenbach DM, Boekelheide K. Seminiferous Tubule Fluid Secretion Is a Sertoli Cell Microtubule-Dependent Process Inhibited by 2,5-Hexanedione Exposure Toxicology and Applied Pharmacology. 128: 302-309. PMID 7940545 DOI: 10.1006/Taap.1994.1210  0.699
1993 Allard EK, Johnson KJ, Boekelheide K. Colchicine disrupts the cytoskeleton of rat testis seminiferous epithelium in a stage-dependent manner. Biology of Reproduction. 48: 143-53. PMID 8418902 DOI: 10.1095/Biolreprod48.1.143  0.344
1993 Johnson KJ, Boekelheide K. Visualization of Golgi complexes and spermatogonial cohorts of viable, intact seminiferous tubules. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 299-306. PMID 7678273 DOI: 10.1177/41.2.7678273  0.358
1992 Hall ES, Eveleth J, Boekelheide K. 2,5-Hexanedione exposure alters the rat Sertoli cell cytoskeleton. II. Intermediate filaments and actin. Toxicology and Applied Pharmacology. 111: 443-53. PMID 1746025 DOI: 10.1016/0041-008X(91)90249-E  0.343
1992 Johnson KJ, Hall ES, Boekelheide K. 2,5-Hexanedione exposure alters the rat Sertoli cell cytoskeleton. I. Microtubules and seminiferous tubule fluid secretion. Toxicology and Applied Pharmacology. 111: 432-42. PMID 1746024 DOI: 10.1016/0041-008X(91)90248-D  0.434
1992 Hall ES, Eveleth J, Jiang C, Redenbach DM, Boekelheide K. Distribution of the microtubule-dependent motors cytoplasmic dynein and kinesin in rat testis. Biology of Reproduction. 46: 817-28. PMID 1534261 DOI: 10.1095/Biolreprod46.5.817  0.373
1992 Boekelheide K, Arcila ME, Eveleth J. cis-diamminedichloroplatinum (II) (cisplatin) alters microtubule assembly dynamics. Toxicology and Applied Pharmacology. 116: 146-51. PMID 1529448 DOI: 10.1016/0041-008X(92)90156-M  0.349
1992 Hall ES, Hall SJ, Boekelheide K. Sertoli cells isolated from adult 2,5-hexanedione-exposed rats exhibit atypical morphology and actin distribution Toxicology and Applied Pharmacology. 117: 9-18. PMID 1359677 DOI: 10.1016/0041-008X(92)90211-A  0.443
1991 Boekelheide K, Hall SJ. 2,5‐Hexanedione Exposure in the Rat Results in Long‐Term Testicular Atrophy Despite the Presence of Residual Spermatogonia Journal of Andrology. 12: 18-26. DOI: 10.1002/J.1939-4640.1991.Tb00208.X  0.355
1990 Boekelheide K, Neely MD, Sioussat TM. The Sertoli cell cytoskeleton: a target for toxicant-induced germ cell loss. Toxicology and Applied Pharmacology. 101: 373-89. PMID 2690397 DOI: 10.1016/0041-008X(89)90188-9  0.405
1990 Sioussat TM, Miller FJ, Boekelheide K. 2,5-Hexanedione-treated tubulin microinjected into sea urchin zygotes induces mitotic abnormalities. Toxicology and Applied Pharmacology. 104: 36-46. PMID 2360208 DOI: 10.1016/0041-008X(90)90280-8  0.371
1990 Boekelheide K, Eveleth J, Hall SJ. Experimental cryptorchidism protects against long-term 2,5-hexanedione-induced testicular germ cell loss in the rat. Journal of Andrology. 11: 105-112. DOI: 10.1002/J.1939-4640.1990.Tb01589.X  0.415
1988 Boekelheide K, Eveleth J, Tatum AH, Winkelman JW. Microtubule assembly inhibition by porphyrins and related compounds. Photochemistry and Photobiology. 46: 657-61. PMID 3441493 DOI: 10.1111/J.1751-1097.1987.Tb04828.X  0.304
1988 Boekelheide K, Eveleth J. The rate of 2,5-hexanedione intoxication, not total dose, determines the extent of testicular injury and altered microtubule assembly in the rat. Toxicology and Applied Pharmacology. 94: 76-83. PMID 3376116 DOI: 10.1016/0041-008X(88)90338-9  0.335
1988 Boekelheide K. Rat testis during 2,5-hexanedione intoxication and recovery. II. Dynamics of pyrrole reactivity, tubulin content, and microtubule assembly. Toxicology and Applied Pharmacology. 92: 28-33. PMID 3341025 DOI: 10.1016/0041-008X(88)90224-4  0.385
1988 Boekelheide K. Rat testis during 2,5-hexanedione intoxication and recovery. I. Dose response and the reversibility of germ cell loss. Toxicology and Applied Pharmacology. 92: 18-27. PMID 3341024 DOI: 10.1016/0041-008X(88)90223-2  0.438
1988 Neely MD, Boekelheide K. Sertoli cell processes have axoplasmic features: an ordered microtubule distribution and an abundant high molecular weight microtubule-associated protein (cytoplasmic dynein). The Journal of Cell Biology. 107: 1767-76. PMID 2972729 DOI: 10.1083/Jcb.107.5.1767  0.324
1987 Boekelheide K. 2,5-Hexanedione alters microtubule assembly. II. Enhanced polymerization of crosslinked tubulin. Toxicology and Applied Pharmacology. 88: 383-96. PMID 3576623 DOI: 10.1016/0041-008X(87)90213-4  0.302
1987 Boekelheide K. 2,5-Hexanedione alters microtubule assembly. I. Testicular atrophy, not nervous system toxicity, correlates with enhanced tubulin polymerization. Toxicology and Applied Pharmacology. 88: 370-82. PMID 3576622 DOI: 10.1016/0041-008X(87)90212-2  0.314
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