Kim Boekelheide - Publications

Brown University, Providence, RI 
Cell Biology, Pathology, Molecular Biology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pendse SN, Maertens A, Rosenberg M, Roy D, Fasani RA, Vantangoli MM, Madnick SJ, Boekelheide K, Fornace AJ, Odwin SA, Yager JD, Hartung T, Andersen ME, McMullen PD. Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity. Archives of Toxicology. PMID 27592001 DOI: 10.1007/s00204-016-1824-6  0.56
2016 Vantangoli MM, Wilson S, Madnick SJ, Huse SM, Boekelheide K. Morphologic Effects of Estrogen Stimulation on 3D MCF-7 Microtissues. Toxicology Letters. PMID 26921789 DOI: 10.1016/j.toxlet.2016.02.012  0.56
2016 Bianchi E, Boekelheide K, Sigman M, Lamb DJ, Hall SJ, Hwang K. Ghrelin ameliorates adhesions in a postsurgical mouse model. The Journal of Surgical Research. 201: 226-34. PMID 26850207 DOI: 10.1016/j.jss.2015.10.044  0.56
2015 Huse SM, Gruppuso PA, Boekelheide K, Sanders JA. Patterns of gene expression and DNA methylation in human fetal and adult liver. Bmc Genomics. 16: 981. PMID 26589361 DOI: 10.1186/s12864-015-2066-3  0.56
2015 Kabadi PK, Vantangoli MM, Rodd AL, Leary E, Madnick SJ, Morgan JR, Kane A, Boekelheide K. Into the depths: Techniques for in vitro three-dimensional microtissue visualization. Biotechniques. 59: 279-86. PMID 26554505 DOI: 10.2144/000114353  0.56
2015 De Paepe ME, Chu S, J Hall S, McDonnell-Clark E, Heger NE, Schorl C, Mao Q, Boekelheide K. Intussusceptive-like angiogenesis in human fetal lung xenografts: Link with bronchopulmonary dysplasia-associated microvascular dysangiogenesis? Experimental Lung Research. 41: 477-88. PMID 26495956 DOI: 10.3109/01902148.2015.1080321  0.56
2015 Spade DJ, Hall SJ, Wilson S, Boekelheide K. Di-n-Butyl Phthalate Induces Multinucleated Germ Cells in the Rat Fetal Testis Through a Non-Proliferative Mechanism. Biology of Reproduction. PMID 26400400 DOI: 10.1095/biolreprod.115.131615  0.56
2015 Curran S, Vantangoli MM, Boekelheide K, Morgan JR. Architecture of Chimeric Spheroids Controls Drug Transport. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 8: 101-9. PMID 26239082 DOI: 10.1007/s12307-015-0171-0  0.56
2015 Saffarini CM, McDonnell-Clark EV, Amin A, Huse SM, Boekelheide K. Developmental exposure to estrogen alters differentiation and epigenetic programming in a human fetal prostate xenograft model. Plos One. 10: e0122290. PMID 25799167 DOI: 10.1371/journal.pone.0122290  0.56
2015 Bouhifd M, Andersen ME, Baghdikian C, Boekelheide K, Crofton KM, Fornace AJ, Kleensang A, Li H, Livi C, Maertens A, McMullen PD, Rosenberg M, Thomas R, Vantangoli M, Yager JD, et al. The human toxome project. Altex. 32: 112-24. PMID 25742299 DOI:  0.56
2014 Spade DJ, McDonnell EV, Heger NE, Sanders JA, Saffarini CM, Gruppuso PA, De Paepe ME, Boekelheide K. Xenotransplantation models to study the effects of toxicants on human fetal tissues. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 101: 410-22. PMID 25477288 DOI: 10.1002/bdrb.21131  0.56
2014 Rider CV, Boekelheide K, Catlin N, Gordon CJ, Morata T, Selgrade MK, Sexton K, Simmons JE. Cumulative risk: toxicity and interactions of physical and chemical stressors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 3-11. PMID 24154487 DOI: 10.1093/toxsci/kft228  0.56
2014 Thompson MR, Burdon A, Boekelheide K. Practice-based evidence informs environmental health policy and regulation: a case study of residential lead-soil contamination in Rhode Island. The Science of the Total Environment. 468: 514-22. PMID 24055667 DOI: 10.1016/j.scitotenv.2013.07.094  0.56
2013 Dere E, Anderson LM, Hwang K, Boekelheide K. Biomarkers of chemotherapy-induced testicular damage. Fertility and Sterility. 100: 1192-202. PMID 24182554 DOI: 10.1016/j.fertnstert.2013.09.017  0.56
2013 Dere E, Anderson LM, Coulson M, McIntyre BS, Boekelheide K, Chapin RE. SOT Symposium Highlight: Translatable Indicators of Testicular Toxicity: Inhibin B, MicroRNAs, and Sperm Signatures. Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 265-73. PMID 24052563 DOI: 10.1093/toxsci/kft207  0.56
2013 Campion S, Aubrecht J, Boekelheide K, Brewster DW, Vaidya VS, Anderson L, Burt D, Dere E, Hwang K, Pacheco S, Saikumar J, Schomaker S, Sigman M, Goodsaid F. The current status of biomarkers for predicting toxicity. Expert Opinion On Drug Metabolism & Toxicology. 9: 1391-408. PMID 23961847 DOI: 10.1517/17425255.2013.827170  0.56
2013 Davis M, Boekelheide K, Boverhof DR, Eichenbaum G, Hartung T, Holsapple MP, Jones TW, Richard AM, Watkins PB. The new revolution in toxicology: the good, the bad, and the ugly. Annals of the New York Academy of Sciences. 1278: 11-24. PMID 23488558 DOI: 10.1111/nyas.12086  0.56
2013 Stephens ML, Andersen M, Becker RA, Betts K, Boekelheide K, Carney E, Chapin R, Devlin D, Fitzpatrick S, Fowle JR, Harlow P, Hartung T, Hoffmann S, Holsapple M, Jacobs A, et al. Evidence-based toxicology for the 21st century: opportunities and challenges. Altex. 30: 74-103. PMID 23338808  0.56
2013 Thompson MR, Boekelheide K. Multiple environmental chemical exposures to lead, mercury and polychlorinated biphenyls among childbearing-aged women (NHANES 1999-2004): Body burden and risk factors. Environmental Research. 121: 23-30. PMID 23158727 DOI: 10.1016/j.envres.2012.10.005  0.56
2012 Springer C, Dere E, Hall SJ, McDonnell EV, Roberts SC, Butt CM, Stapleton HM, Watkins DJ, McClean MD, Webster TF, Schlezinger JJ, Boekelheide K. Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dust. Environmental Health Perspectives. 120: 1711-9. PMID 23014847 DOI: 10.1289/ehp.1204932  0.56
2012 Pacheco SE, Anderson LM, Sandrof MA, Vantangoli MM, Hall SJ, Boekelheide K. Sperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat. Plos One. 7: e44280. PMID 22952946 DOI: 10.1371/journal.pone.0044280  0.56
2012 Johnson KJ, Heger NE, Boekelheide K. Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 235-48. PMID 22700540 DOI: 10.1093/toxsci/kfs206  0.56
2012 Boekelheide K, Blumberg B, Chapin RE, Cote I, Graziano JH, Janesick A, Lane R, Lillycrop K, Myatt L, States JC, Thayer KA, Waalkes MP, Rogers JM. Predicting later-life outcomes of early-life exposures. Environmental Health Perspectives. 120: 1353-61. PMID 22672778 DOI: 10.1289/ehp.1204934  0.56
2012 Heger NE, Hall SJ, Sandrof MA, McDonnell EV, Hensley JB, McDowell EN, Martin KA, Gaido KW, Johnson KJ, Boekelheide K. Human fetal testis xenografts are resistant to phthalate-induced endocrine disruption. Environmental Health Perspectives. 120: 1137-43. PMID 22511013 DOI: 10.1289/ehp.1104711  0.56
2012 Pacheco SE, Anderson LM, Boekelheide K. Optimization of a filter-lysis protocol to purify rat testicular homogenates for automated spermatid counting. Journal of Andrology. 33: 811-6. PMID 22240558 DOI: 10.2164/jandrol.111.015131  0.56
2012 Seifert EL, Caron AZ, Morin K, Coulombe J, He XH, Jardine K, Dewar-Darch D, Boekelheide K, Harper ME, McBurney MW. SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 555-66. PMID 22006156 DOI: 10.1096/fj.11-193979  0.56
2012 Stephens ML, Barrow C, Andersen ME, Boekelheide K, Carmichael PL, Holsapple MP, Lafranconi M. Accelerating the development of 21st-century toxicology: outcome of a Human Toxicology Project Consortium workshop. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 327-34. PMID 21948868 DOI: 10.1093/toxsci/kfr248  0.56
2011 Andersen ME, Clewell HJ, Carmichael PL, Boekelheide K. Can case study approaches speed implementation of the NRC report: "toxicity testing in the 21st century: a vision and a strategy?". Altex. 28: 175-82. PMID 21993955  0.56
2011 Bhattacharya S, Zhang Q, Carmichael PL, Boekelheide K, Andersen ME. Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways. Plos One. 6: e20887. PMID 21701582 DOI: 10.1371/journal.pone.0020887  0.56
2010 Krewski D, Acosta D, Andersen M, Anderson H, Bailar JC, Boekelheide K, Brent R, Charnley G, Cheung VG, Green S, Kelsey KT, Kerkvliet NI, Li AA, McCray L, Meyer O, et al. Toxicity testing in the 21st century: a vision and a strategy. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 51-138. PMID 20574894 DOI: 10.1080/10937404.2010.483176  0.56
2009 Paul E, Cronan R, Weston PJ, Boekelheide K, Sedivy JM, Lee SY, Wiest DL, Resnick MB, Klysik JE. Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 92-108. PMID 19145458 DOI: 10.1007/s00335-008-9168-z  0.56
2008 Boekelheide K, Sigman M. Is gene therapy for the treatment of male infertility feasible? Nature Clinical Practice. Urology. 5: 590-3. PMID 18852706 DOI: 10.1038/ncpuro1234  0.56
2008 Chapin RE, Adams J, Boekelheide K, Gray LE, Hayward SW, Lees PS, McIntyre BS, Portier KM, Schnorr TM, Selevan SG, Vandenbergh JG, Woskie SR. NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 83: 157-395. PMID 18613034 DOI: 10.1002/bdrb.20147  0.56
2008 Ryu KY, Sinnar SA, Reinholdt LG, Vaccari S, Hall S, Garcia MA, Zaitseva TS, Bouley DM, Boekelheide K, Handel MA, Conti M, Kopito RR. The mouse polyubiquitin gene Ubb is essential for meiotic progression. Molecular and Cellular Biology. 28: 1136-46. PMID 18070917 DOI: 10.1128/MCB.01566-07  0.56
2008 Klysik J, Theroux SJ, Sedivy JM, Moffit JS, Boekelheide K. Signaling crossroads: the function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction. Cellular Signalling. 20: 1-9. PMID 17706925 DOI: 10.1016/j.cellsig.2007.07.003  0.56
2007 Moffit JS, Bryant BH, Hall SJ, Boekelheide K. Dose-dependent effects of sertoli cell toxicants 2,5-hexanedione, carbendazim, and mono-(2-ethylhexyl) phthalate in adult rat testis. Toxicologic Pathology. 35: 719-27. PMID 17763286 DOI: 10.1080/01926230701481931  0.56
2007 Moffit JS, Boekelheide K, Sedivy JM, Klysik J. Mice lacking Raf kinase inhibitor protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury. Journal of Andrology. 28: 883-90. PMID 17554109 DOI: 10.2164/jandrol.107.002964  0.56
2007 Gaido KW, Hensley JB, Liu D, Wallace DG, Borghoff S, Johnson KJ, Hall SJ, Boekelheide K. Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 491-503. PMID 17361019 DOI: 10.1093/toxsci/kfm049  0.56
2007 Rasoulpour RJ, Boekelheide K. NF-kappaB activation elicited by ionizing radiation is proapoptotic in testis. Biology of Reproduction. 76: 279-85. PMID 17123945 DOI: 10.1095/biolreprod.106.054924  0.8
2006 Emerich DF, Thanos CG, Goddard M, Skinner SJ, Geany MS, Bell WJ, Bintz B, Schneider P, Chu Y, Babu RS, Borlongan CV, Boekelheide K, Hall S, Bryant B, Kordower JH. Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys. Neurobiology of Disease. 23: 471-80. PMID 16777422 DOI: 10.1016/j.nbd.2006.04.014  0.56
2006 Rasoulpour RJ, Boekelheide K. The Sycp1-Cre transgenic mouse and male germ cell inhibition of NF-kappa b. Journal of Andrology. 27: 729-33. PMID 16775250 DOI: 10.2164/jandrol.106.000950  0.8
2005 Beall SA, Boekelheide K, Johnson KJ. Hybrid GPCR/cadherin (Celsr) proteins in rat testis are expressed with cell type specificity and exhibit differential Sertoli cell-germ cell adhesion activity. Journal of Andrology. 26: 529-38. PMID 15955893 DOI: 10.2164/jandrol.05003  0.36
2005 Boekelheide K, Schoenfeld HA, Hall SJ, Weng CC, Shetty G, Leith J, Harper J, Sigman M, Hess DL, Meistrich ML. Gonadotropin-releasing hormone antagonist (Cetrorelix) therapy fails to protect nonhuman primates (Macaca arctoides) from radiation-induced spermatogenic failure. Journal of Andrology. 26: 222-34. PMID 15713828  0.56
2005 Rasoulpour RJ, Boekelheide K. NF-kappaB is activated in the rat testis following exposure to mono-(2-ethylhexyl) phthalate. Biology of Reproduction. 72: 479-86. PMID 15496515 DOI: 10.1095/biolreprod.104.034363  0.8
2005 Augustine LM, Markelewicz RJ, Boekelheide K, Cherrington NJ. Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 182-9. PMID 15494472 DOI: 10.1124/dmd.104.001024  0.56
2004 Markelewicz RJ, Hall SJ, Boekelheide K. 2,5-hexanedione and carbendazim coexposure synergistically disrupts rat spermatogenesis despite opposing molecular effects on microtubules. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 92-100. PMID 15141104 DOI: 10.1093/toxsci/kfh140  0.56
2004 Boekelheide K, Darney SP, Daston GP, David RM, Luderer U, Olshan AF, Sanderson WT, Willhite CC, Woskie S. NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of 2-bromopropane. Reproductive Toxicology (Elmsford, N.Y.). 18: 189-217. PMID 15019719 DOI: 10.1016/j.reprotox.2003.10.003  0.56
2003 Rasoulpour RJ, Schoenfeld HA, Gray DA, Boekelheide K. Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging. The American Journal of Pathology. 163: 2595-603. PMID 14633631 DOI: 10.1016/S0002-9440(10)63614-0  0.56
2003 Hixon ML, Boekelheide K. Expression and localization of total Akt1 and phosphorylated Akt1 in the rat seminiferous epithelium. Journal of Andrology. 24: 891-8. PMID 14581516  0.56
2003 Fleming SL, Shank PR, Boekelheide K. gamma-Tubulin overexpression in Sertoli cells in vivo: I. Localization to sites of spermatid head attachment and alterations in Sertoli cell microtubule distribution. Biology of Reproduction. 69: 310-21. PMID 12672673 DOI: 10.1095/biolreprod.102.011791  0.56
2003 Fleming SL, Shank PR, Boekelheide K. gamma-Tubulin overexpression in Sertoli cells in vivo. II: Retention of spermatids, residual bodies, and germ cell apoptosis. Biology of Reproduction. 69: 322-30. PMID 12672672 DOI: 10.1095/biolreprod.102.011817  0.56
2003 McBurney MW, Yang X, Jardine K, Hixon M, Boekelheide K, Webb JR, Lansdorp PM, Lemieux M. The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis. Molecular and Cellular Biology. 23: 38-54. PMID 12482959 DOI: 10.1128/MCB.23.1.38-54.2003  0.56
2003 Boekelheide K, Fleming SL, Allio T, Embree-Ku ME, Hall SJ, Johnson KJ, Kwon EJ, Patel SR, Rasoulpour RJ, Schoenfeld HA, Thompson S. 2,5-hexanedione-induced testicular injury. Annual Review of Pharmacology and Toxicology. 43: 125-47. PMID 12471174 DOI: 10.1146/annurev.pharmtox.43.100901.135930  0.56
2002 Johnson KJ, Boekelheide K. Dynamic testicular adhesion junctions are immunologically unique. II. Localization of classic cadherins in rat testis. Biology of Reproduction. 66: 992-1000. PMID 11906918  0.36
2002 Johnson KJ, Boekelheide K. Dynamic testicular adhesion junctions are immunologically unique. I. Localization of p120 catenin in rat testis. Biology of Reproduction. 66: 983-91. PMID 11906917  0.36
2000 Richburg JH, Nan Ez A, Williams LR, Embree ME, Boekelheide K. Sensitivity of Testicular Germ Cells to Toxicant-Induced Apoptosis in gld Mice That Express a Nonfunctional Form of Fas Ligand1. Endocrinology. 141: 787-793. PMID 28201080 DOI: 10.1210/endo.141.2.7325  0.48
2000 Johnson KJ, Patel SR, Boekelheide K. Multiple Cadherin Superfamily Members with Unique Expression Profiles Are Produced in Rat Testis1. Endocrinology. 141: 675-683. PMID 28200949 DOI: 10.1210/endo.141.2.7334  0.36
2000 Boekelheide K, Fleming SL, Johnson KJ, Patel SR, Schoenfeld HA. Role of Sertoli cells in injury-associated testicular germ cell apoptosis. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 225: 105-15. PMID 11044252 DOI: 10.1046/j.1525-1373.2000.22513.x  0.56
2000 Richburg JH, Nañez A, Williams LR, Embree ME, Boekelheide K. Sensitivity of testicular germ cells to toxicant-induced apoptosis in gld mice that express a nonfunctional form of Fas ligand. Endocrinology. 141: 787-93. PMID 10650961 DOI: 10.1210/endo.141.2.7325  0.56
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