Maria L. Lung - Publications

Affiliations: 
Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 
Area:
Genetics, Cell Biology

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tan Z, Ko JM, Yu VZ, Lam KO, Kwong DL, Wong IY, Chan FS, Wong CL, Chan KK, Law TT, Choy FS, Ng HY, Law SY, Lung ML. Multigene Profiling of Circulating Tumor Cells in Esophageal Squamous Cell Carcinoma Identifies Prognostic Cancer Driver Genes Associated with Epithelial-Mesenchymal-Transition Progression and Chemoresistance. Cancers. 15. PMID 38001588 DOI: 10.3390/cancers15225329  0.373
2023 Ng HY, Ko JMY, Lam KO, Kwong DLW, Lo AWI, Wong IYH, Wong CLY, Chan SY, Chan KK, Law TT, Dai W, Fong HCH, Choy FSF, Lo CK, Chen C, ... ... Lung ML, et al. Circulating Tumor DNA Dynamics as Prognostic Markers in Locally Advanced and Metastatic Esophageal Squamous Cell Carcinoma. Jama Surgery. PMID 37728901 DOI: 10.1001/jamasurg.2023.4395  0.321
2023 Chen L, Chau WY, Yuen HT, Liu XH, Qi RZ, Lung ML, Lung HL. THY1 (CD90) Maintains the Adherens Junctions in Nasopharyngeal Carcinoma via Inhibition of SRC Activation. Cancers. 15. PMID 37046850 DOI: 10.3390/cancers15072189  0.408
2022 Ko JM, Guo C, Liu C, Ning L, Dai W, Tao L, Lo AW, Wong CW, Wong IY, Chan FS, Wong CL, Chan KK, Law TT, Lee NP, Liu Z, ... ... Lung ML, et al. Clonal relationship and alcohol consumption-associated mutational signature in synchronous hypopharyngeal tumours and oesophageal squamous cell carcinoma. British Journal of Cancer. PMID 36261585 DOI: 10.1038/s41416-022-01995-0  0.306
2021 Li J, Ko JM, Dai W, Yu VZ, Ng HY, Hoffmann JS, Lung ML. Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes Genome Instability through the cGAS-STING-ISG Pathway in Esophageal Squamous Cell Carcinoma. Cancers. 13. PMID 34206946 DOI: 10.3390/cancers13133204  0.41
2021 Ana Choi SS, Ko JM, Yu VZ, Ning L, Lung ML. Differentiation-related zinc finger protein 750 suppresses cell growth in esophageal squamous cell carcinoma. Oncology Letters. 22: 513. PMID 33986873 DOI: 10.3892/ol.2021.12774  0.421
2020 Lei LC, Yu VZ, Ko JMY, Ning L, Lung ML. FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression. Cancers. 12. PMID 32906798 DOI: 10.3390/Cancers12092545  0.534
2020 Chan LS, Lung HL, Ngan RK, Lee AW, Tsao SW, Lo KW, Kahn M, Lung ML, Wieser R, Mak NK. Role of miR-96/EVI1/miR-449a Axis in the Nasopharyngeal Carcinoma Cell Migration and Tumor Sphere Formation. International Journal of Molecular Sciences. 21. PMID 32752071 DOI: 10.3390/Ijms21155495  0.372
2020 Deng M, Dai W, Yu VZ, Tao L, Lung ML. Cylindromatosis Lysine 63 Deubiquitinase (CYLD) Regulates NF-kB Signaling Pathway and Modulates Fibroblast and Endothelial Cells Recruitment in Nasopharyngeal Carcinoma. Cancers. 12. PMID 32708712 DOI: 10.3390/Cancers12071924  0.482
2020 Ko JMY, Ng HY, Lam KO, Chiu KWH, Kwong DLW, Lo AWI, Wong JC, Lin RCW, Fong HCH, Li JYK, Dai W, Law S, Lung ML. Liquid Biopsy Serial Monitoring of Treatment Responses and Relapse in Advanced Esophageal Squamous Cell Carcinoma. Cancers. 12. PMID 32466419 DOI: 10.3390/Cancers12061352  0.339
2020 Guo YM, Chen JR, Feng YC, Chua MLK, Zeng Y, Hui EP, Chan AKC, Tang LQ, Wang L, Cui Q, Han HQ, Luo CL, Lin GW, Liang Y, Liu Y, ... ... Lung ML, et al. Germline Polymorphisms and Length of Survival of Nasopharyngeal Carcinoma: An Exome-Wide Association Study in Multiple Cohorts. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1903727. PMID 32440486 DOI: 10.1002/Advs.201903727  0.324
2020 Ko JM, Vardhanabhuti V, Ng WT, Lam KO, Ngan RK, Kwong DL, Lee VH, Lui YH, Yau CC, Kwan CK, Li WS, Yau S, Guo C, Choi SSA, Lei LC, ... ... Lung ML, et al. Clinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma. British Journal of Cancer. PMID 32372027 DOI: 10.1038/S41416-020-0871-1  0.358
2020 Jiang C, Li L, Xiang YQ, Lung ML, Zeng T, Lu J, Tsao SW, Zeng MS, Yun JP, Kwong DL, Guan XY. Epstein-Barr Virus microRNA BART2-5p promotes metastasis of nasopharyngeal carcinoma by suppressing RND3. Cancer Research. PMID 32060148 DOI: 10.1158/0008-5472.Can-19-0334  0.404
2020 Yu VZ, Ip JCY, Ko JMY, Tao L, Lam AK, Lung ML. Orthotopic Xenograft Mouse Model in Esophageal Squamous Cell Carcinoma. Methods in Molecular Biology (Clifton, N.J.). 2129: 149-160. PMID 32056176 DOI: 10.1007/978-1-0716-0377-2_12  0.476
2020 Ko JM, Ng BH, Lung ML. Abstract 5371: Real-time serial monitoring of liquid biopsies allows earlier detection of treatment responses and relapse for metastatic esophageal squamous cell carcinoma Clinical Trials. 80: 5371-5371. DOI: 10.1158/1538-7445.Am2020-5371  0.447
2019 Verhoeven RJA, Tong S, Mok BW, Liu J, He S, Zong J, Chen Y, Tsao SW, Lung ML, Chen H. Epstein-Barr Virus BART Long Non-coding RNAs Function as Epigenetic Modulators in Nasopharyngeal Carcinoma. Frontiers in Oncology. 9: 1120. PMID 31696060 DOI: 10.3389/Fonc.2019.01120  0.387
2019 Leong MML, Cheung AKL, Kwok TCT, Lung ML. Functional Characterization of a Candidate Tumor Suppressor Gene, Mirror Image Polydactyly 1, in Nasopharyngeal Carcinoma. International Journal of Cancer. PMID 31609475 DOI: 10.1002/Ijc.32732  0.539
2019 Lung HL, Kan R, Chau WY, Man OY, Mak NK, Fong CH, Shuen WH, Tsao SW, Lung ML. The anti-tumor function of the IKK inhibitor PS1145 and high levels of p65 and KLF4 are associated with the drug resistance in nasopharyngeal carcinoma cells. Scientific Reports. 9: 12064. PMID 31427673 DOI: 10.1038/S41598-019-48590-7  0.456
2019 Ko JM, Ning L, Zhao XK, Chai AW, Lei LC, Choi SSA, Tao L, Law S, Kwong A, Lee NP, Chan KT, Lo A, Song X, Chen PN, Chang YL, ... ... Lung ML, et al. BRCA2 loss-of-function germline mutations are associated with esophageal squamous cell carcinoma risk in Chinese. International Journal of Cancer. PMID 31396961 DOI: 10.1002/Ijc.32619  0.378
2019 Chen L, Chan LS, Lung HL, Yip TTC, Ngan RKC, Wong JWC, Lo KW, Ng WT, Lee AWM, Tsao GSW, Lung ML, Mak NK. Crucifera sulforaphane (SFN) inhibits the growth of nasopharyngeal carcinoma through DNA methyltransferase 1 (DNMT1)/Wnt inhibitory factor 1 (WIF1) axis. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 63: 153058. PMID 31394414 DOI: 10.1016/J.Phymed.2019.153058  0.448
2019 Yu VZ, Yee Ko JM, Ning L, Dai W, Law S, Lung ML. Endoplasmic reticulum-localized ECM1b suppresses tumor growth and regulates MYC and MTORC1 through modulating MTORC2 activation in esophageal squamous cell carcinoma. Cancer Letters. PMID 31319137 DOI: 10.1016/J.Canlet.2019.07.005  0.508
2019 Leong MML, Cheung AKL, Dai W, Tsao SW, Tsang CM, Dawson CW, Mun Yee Ko J, Lung ML. EBV infection is associated with histone bivalent switch modifications in squamous epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31235597 DOI: 10.1073/Pnas.1821752116  0.327
2019 Zhang J, Jia L, Liu T, Yip YL, Tang WC, Lin W, Deng W, Lo KW, You C, Lung ML, Lung HL, Cheung AL, Tsao SW, Tsang CM. mTORC2-mediated PDHE1α nuclear translocation links EBV-LMP1 reprogrammed glucose metabolism to cancer metastasis in nasopharyngeal carcinoma. Oncogene. PMID 30745576 DOI: 10.1038/S41388-019-0749-Y  0.377
2019 Leong MML, Cheung AKL, Dai W, Tsao SW, Lung ML. Abstract 5192: EBV-associated histone modifications regulate DNA damage repair pathway and associate with cisplatin resistance in nasopharyngeal epithelial malignancy Cancer Research. 79: 5192-5192. DOI: 10.1158/1538-7445.Sabcs18-5192  0.39
2019 Lei C, Yu Z, Ning L, Ko M, Wang L, Lung ML. Abstract 3465: FANCD2 depletion suppresses tumor growth in esophageal squamous cell carcinoma Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3465  0.718
2019 Choi SS, Yu VZ, Ko JM, Dai W, Lung ML. Abstract 174: Functional characterization of ZNF750 in esophageal squamous cell carcinoma Cancer Research. 79: 174-174. DOI: 10.1158/1538-7445.Sabcs18-174  0.524
2019 Lin W, Yip YL, Jia L, Deng W, Lo KW, Tsang CM, Lung ML, Tsao GS. Abstract 56: Establishment and characterization of new tumor xenografts and cancer cell lines from EBV positive nasopharyngeal carcinoma Cancer Research. 79: 56-56. DOI: 10.1158/1538-7445.Am2019-56  0.468
2018 Chan LS, Man OY, Kwok HH, Chen L, Chan KC, Lung HL, Ngan RK, Wong RN, Lo KW, Lee AW, Tsao GS, Kahn M, Lung ML, Mak NK. The Wnt modulator ICG‑001 mediates the inhibition of nasopharyngeal carcinoma cell migration in vitro via the miR‑150/CD44 axis. International Journal of Oncology. PMID 30569106 DOI: 10.3892/Ijo.2018.4664  0.393
2018 Hui KF, Chan TF, Yang W, Shen JJ, Lam KP, Kwok H, Sham PC, Tsao SW, Kwong DL, Lung ML, Chiang AKS. High risk Epstein-Barr virus variants characterized by distinct polymorphisms in the EBER locus are strongly associated with nasopharyngeal carcinoma. International Journal of Cancer. PMID 30536939 DOI: 10.1002/Ijc.32049  0.334
2018 Lin W, Yip YL, Jia L, Deng W, Zheng H, Dai W, Ko JMY, Lo KW, Chung GTY, Yip KY, Lee SD, Kwan JS, Zhang J, Liu T, Chan JY, ... ... Lung ML, et al. Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma. Nature Communications. 9: 4663. PMID 30405107 DOI: 10.1038/S41467-018-06889-5  0.424
2018 Yip YL, Lin W, Deng W, Jia L, Lo KW, Busson P, Vérillaud B, Liu X, Tsang CM, Lung ML, Tsao SW. Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein-Barr virus reactivation. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29769697 DOI: 10.1038/S41374-018-0034-7  0.377
2018 Ng WT, Ngan RKC, Kwong DLW, Tung SY, Yuen KT, Kam MKM, Sze HCK, Yiu HHY, Chan LLK, Lung ML, Lee AWM. Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma. International Journal of Radiation Oncology, Biology, Physics. 100: 630-638. PMID 29413277 DOI: 10.1016/J.Ijrobp.2017.11.038  0.302
2018 Leong MML, Cheung AKL, Kwok TCT, Lung ML. Abstract 5521: Functional characterization of a candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma Cancer Research. 78: 5521-5521. DOI: 10.1158/1538-7445.Am2018-5521  0.567
2018 Lam SY, Ning L, Ng HY, Lung ML, Ko JM. Abstract 327: Functional characterization of RAD50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma Cancer Research. 78: 327-327. DOI: 10.1158/1538-7445.Am2018-327  0.427
2018 Lei LC, Yu VZ, Ning L, Ko JM, Wang LD, Lung ML. Abstract 1357: Functional characterization of FANCD2 in esophageal squamous cell carcinoma Cancer Research. 78: 1357-1357. DOI: 10.1158/1538-7445.Am2018-1357  0.524
2017 Lung HL, Lo PHY, Xie D, Apte SS, Cheung AKL, Cheng Y, Law EWL, Chua D, Zeng YX, Tsao SW, Stanbridge EJ, Lung ML. Erratum to: Expression of concern: Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9, and its association with lymph node metastases in nasopharyngeal carcinoma : ADAMTS9 Gene in Nasopharyngeal Carcinoma (International Journal of Cancer, (2008), 123, 2, (401-408), 10.1002/ijc.23528) International Journal of Cancer. 141. PMID 32872707 DOI: 10.1002/Ijc.31032  0.582
2017 Chai AWY, Cheung AKL, Dai W, Ko JMY, Lee NPY, Chan KT, Law SY, Lung ML. Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma. Cancer Biomarkers : Section a of Disease Markers. PMID 29278876 DOI: 10.3233/Cbm-170484  0.394
2017 Dai W, Ko JMY, Choi SSA, Yu Z, Ning L, Zheng H, Gopalan V, Chan KT, Lee NP, Chan KW, Law SY, Lam AK, Lung ML. Whole-exome sequencing reveals critical genes underlying metastasis in esophageal squamous cell carcinoma. The Journal of Pathology. PMID 28608921 DOI: 10.1002/Path.4925  0.44
2017 Wong VC, Ko JM, Lam CT, Lung ML. Succinct workflows for circulating tumor cells after enrichment: From systematic counting to mutational profiling. Plos One. 12: e0177276. PMID 28481895 DOI: 10.1371/Journal.Pone.0177276  0.385
2017 Zhang J, Jia L, Lin W, Yip YL, Lo KW, Lau VM, Zhu D, Tsang CM, Zhou Y, Deng W, Lung HL, Lung ML, Cheung LM, Tsao SW. Epstein-Barr Virus encoded Latent Membrane Protein-1 upregulates glucose transporter-1 transcription via the mTORC1/NF-κB signaling pathways. Journal of Virology. PMID 28053105 DOI: 10.1128/Jvi.02168-16  0.315
2017 Dai W, Zheng H, Ko JMY, Cheung AKL, Lung ML. Abstract 14: Elucidation of genetic susceptibility genes using next-generation sequencing (NGS) approach in nasopharyngeal carcinoma Clinical Cancer Research. 23: 14-14. DOI: 10.1158/1557-3265.Aacrahns17-14  0.389
2017 Jiang L, Lan R, Huang T, Chan C, Li H, Lear S, Zong J, Wong W, Lee MM, Chan BD, Chan W, Lo W, Mak N, Lung ML, Lung HL, et al. EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein–Barr virus Nature Biomedical Engineering. 1: 1-10. DOI: 10.1038/S41551-017-0042  0.355
2016 Chai AW, Cheung AK, Dai W, Ko JM, Ip JC, Chan KW, Kwong DL, Ng WT, Lee AW, Ngan RK, Yau CC, Tung SY, Lee VH, Lam AK, Pillai S, ... ... Lung ML, et al. Metastasis-suppressing NID2, an epigenetically-silenced gene, in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma. Oncotarget. PMID 27793011 DOI: 10.18632/Oncotarget.12889  0.504
2016 Zheng H, Dai W, Cheung AK, Ko JM, Kan R, Wong BW, Leong MM, Deng M, Kwok TC, Chan JY, Kwong DL, Lee AW, Ng WT, Ngan RK, Yau CC, ... ... Lung ML, et al. Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27647909 DOI: 10.1073/Pnas.1607606113  0.388
2016 Ip JC, Ko JM, Yu VZ, Chan KW, Lam AK, Law S, Tong DK, Lung ML. Corrigendum to "A Versatile Orthotopic Nude Mouse Model for Study of Esophageal Squamous Cell Carcinoma". Biomed Research International. 2016: 2348673. PMID 27462607 DOI: 10.1155/2016/2348673  0.407
2016 Dai W, Zheng H, Cheung AK, Lung ML. Genetic and epigenetic landscape of nasopharyngeal carcinoma. Chinese Clinical Oncology. 5: 16. PMID 27121876 DOI: 10.21037/Cco.2016.03.06  0.43
2016 Dai W, Zheng H, Cheung AK, Tang CS, Ko JM, Wong BW, Leong MM, Sham PC, Cheung F, Kwong DL, Ngan RK, Ng WT, Yau CC, Pan J, Peng X, ... ... Lung ML, et al. Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951679 DOI: 10.1073/Pnas.1523436113  0.404
2016 Ng HY, Ko JM, Yu VZ, Ip JC, Dai W, Cal S, Lung ML. DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma. International Journal of Cancer. Journal International Du Cancer. PMID 26856390 DOI: 10.1002/Ijc.30034  0.516
2016 Ko JMY, Ni Lw, Sheyne SAC, Lei LC, Wang LD, Lung ML. Abstract 5234: Rare deleterious germline mutations of candidate genes associated with risk of familial esophageal squamous cell carcinoma (ESCC) by targeted sequencing Cancer Research. 76: 5234-5234. DOI: 10.1158/1538-7445.Am2016-5234  0.392
2016 Lung ML, Cheung AK, Dai W, Leong MM, GST. Abstract 4522: Epstein-Barr virus infection suppresses the DNA repair mechanisms in nasopharyngeal epithelial cells via reduction of the H3K4me3 mark Cancer Research. 76: 4522-4522. DOI: 10.1158/1538-7445.Am2016-4522  0.387
2016 Zheng H, Dai W, Cheung AK, Ko JM, Kan R, Wong BW, Leong MM, Lung ML. Abstract 125: Whole-exome sequencing identifies NF-kappaB pathway regulators frequently mutated in nasopharyngeal carcinoma Cancer Research. 76: 125-125. DOI: 10.1158/1538-7445.Am2016-125  0.381
2016 Yu VZ, Ko JM, Law S, Wang LD, Lung ML. Abstract 1158: Differential expression and functional impact of the alternatively spliced transcripts of Extracellular matrix protein 1 in esophageal squamous cell carcinoma Cancer Research. 76: 1158-1158. DOI: 10.1158/1538-7445.Am2016-1158  0.502
2015 Zhu DD, Zhang J, Deng W, Yip YL, Lung HL, Tsang CM, Law WT, Yang J, Lau VM, Lung ML, Cheung AL, Tsao SW. Significance of NF-κB activation in immortalization of nasopharyngeal epithelial cells. International Journal of Cancer. Journal International Du Cancer. PMID 26370441 DOI: 10.1002/Ijc.29850  0.331
2015 Yu VZ, Wong VC, Dai W, Ko JM, Lam AK, Chan KW, Samant RS, Lung HL, Shuen WH, Law S, Chan YP, Lee NP, Tong DK, Law TT, Lee VH, ... Lung ML, et al. Nuclear Localization of DNAJB6 is Associated with Survival of Patients with Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells. Gastroenterology. PMID 26302489 DOI: 10.1053/J.Gastro.2015.08.025  0.366
2015 Phoon YP, Cheung AK, Cheung FM, Chan KF, Wong S, Wong BW, Tung SY, Yau CC, Ng WT, Lung ML. IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-κB-mediated signalling. International Journal of Cancer. Journal International Du Cancer. PMID 26227166 DOI: 10.1002/Ijc.29702  0.484
2015 Hui KF, Cheung AK, Choi CK, Yeung PL, Middeldorp JM, Lung ML, Tsao SW, Chiang AK. Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir. International Journal of Cancer. Journal International Du Cancer. PMID 26205347 DOI: 10.1002/Ijc.29698  0.343
2015 Cheng Y, Phoon YP, Jin X, Chong SY, Ip JC, Wong BW, Lung ML. Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment. Oncotarget. PMID 25980501 DOI: 10.18632/Oncotarget.3982  0.613
2015 Kan R, Shuen WH, Lung HL, Cheung AK, Dai W, Kwong DL, Ng WT, Lee AW, Yau CC, Ngan RK, Tung SY, Lung ML. NF-κB p65 Subunit Is Modulated by Latent Transforming Growth Factor-β Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells. Plos One. 10: e0127239. PMID 25974126 DOI: 10.1371/Journal.Pone.0127239  0.456
2015 Cheung AK, Ip JC, Chu AC, Cheng Y, Leong MM, Ko JM, Shuen WH, Lung HL, Lung ML. PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma. Oncotarget. 6: 13434-47. PMID 25970784 DOI: 10.18632/Oncotarget.3876  0.642
2015 Dai W, Cheung AK, Ko JM, Cheng Y, Zheng H, Ngan RK, Ng WT, Lee AW, Yau CC, Lee VH, Lung ML. Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinoma. Cancer Medicine. 4: 1079-90. PMID 25924914 DOI: 10.1002/Cam4.451  0.599
2015 Chan KC, Chan LS, Ip JC, Lo C, Yip TT, Ngan RK, Wong RN, Lo KW, Ng WT, Lee AW, Tsao GS, Kahn M, Lung ML, Mak NK. Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin. Scientific Reports. 5: 9979. PMID 25897700 DOI: 10.1038/Srep09979  0.463
2015 Chan YK, Zhang H, Liu P, Tsao SW, Lung ML, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P. Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins. International Journal of Cancer. Journal International Du Cancer. PMID 25857718 DOI: 10.1002/Ijc.29562  0.388
2015 Ip JC, Ko JM, Yu VZ, Chan KW, Lam AK, Law S, Tong DK, Lung ML. A versatile orthotopic nude mouse model for study of esophageal squamous cell carcinoma. Biomed Research International. 2015: 910715. PMID 25834829 DOI: 10.1155/2015/910715  0.531
2015 Shuen WH, Kan R, Yu Z, Lung HL, Lung ML. Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies. Cancer Gene Therapy. 22: 207-14. PMID 25721206 DOI: 10.1038/Cgt.2015.9  0.417
2015 Yang X, Dai W, Kwong DL, Szeto CY, Wong EH, Ng WT, Lee AW, Ngan RK, Yau CC, Tung SY, Lung ML. Epigenetic markers for noninvasive early detection of nasopharyngeal carcinoma by methylation-sensitive high resolution melting. International Journal of Cancer. Journal International Du Cancer. 136: E127-35. PMID 25196065 DOI: 10.1002/Ijc.29192  0.349
2015 Lung HL, Man OY, Yeung MC, Ko JM, Cheung AK, Law EW, Yu Z, Shuen WH, Tung E, Chan SH, Bangarusamy DK, Cheng Y, Yang X, Kan R, Phoon Y, ... ... Lung ML, et al. SAA1 polymorphisms are associated with variation in antiangiogenic and tumor-suppressive activities in nasopharyngeal carcinoma. Oncogene. 34: 878-89. PMID 24608426 DOI: 10.1038/Onc.2014.12  0.644
2015 Dai W, Cheung AKL, Ko JMY, Zheng H, Cheng Y, Ngan RKC, Ng WT, Lee AWM, Yau CC, Lee VHF, Lung ML. Abstract 4773: Aberrant methylation at chromosome 6p as novel biomarkers for diagnosis and prognosis of nasopharyngeal carcinoma Cancer Research. 75: 4773-4773. DOI: 10.1158/1538-7445.Am2015-4773  0.553
2015 Zheng H, Dai W, Tang C, Cheung A, Ko J, Sham P, Lung ML. Abstract 1921: Unraveling the genetic basis of nasopharyngeal carcinoma using next-generation sequencing approaches Cancer Research. 75: 1921-1921. DOI: 10.1158/1538-7445.Am2015-1921  0.363
2015 Ngan RK, Ng WT, Kwong D, Tung S, Yau CC, Leung SF, Chan WY, Lung M, Lee A. 334PPreliminary results of HKNPC-1001 trial to evaluate the role of induction TPF followed by weekly docetaxel and cetuximab in combination with intensity modulated radiotherapy for locally recurrent nasopharyngeal carcinoma Annals of Oncology. 26. DOI: 10.1093/Annonc/Mdv527.21  0.319
2014 Lung ML, Cheung AK, Ko JM, Lung HL, Cheng Y, Dai W. The interplay of host genetic factors and Epstein-Barr virus in the development of nasopharyngeal carcinoma. Chinese Journal of Cancer. 33: 556-68. PMID 25367335 DOI: 10.5732/Cjc.014.10170  0.561
2014 Cheng Y, Ho RL, Chan KC, Kan R, Tung E, Lung HL, Yau WL, Cheung AK, Ko JM, Zhang ZF, Luo DZ, Feng ZB, Chen S, Guan XY, Kwong D, ... ... Lung ML, et al. Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma. Oncogene. PMID 25347745 DOI: 10.1038/Onc.2014.353  0.646
2014 Ko JM, Zhang P, Law S, Fan Y, Song YQ, Zhao XK, Wong EH, Tang S, Song X, Lung ML, Wang LD. Identity-by-descent approaches identify regions of importance for genetic susceptibility to hereditary esophageal squamous cell carcinoma. Oncology Reports. 32: 860-70. PMID 24890309 DOI: 10.3892/Or.2014.3222  0.346
2014 Yu VZ, Wong VCL, Chan KW, Lung ML. Abstract 594: DNAJB6a as tumor suppressor in esophageal squamous cell carcinoma Cancer Research. 74: 594-594. DOI: 10.1158/1538-7445.Am2014-594  0.535
2014 Lung ML, Ko J, Dai W, Wong E, Kwong D, Ng WT, Lee A, Ngan R, Yau CC, Tung S. Abstract 4148: Adverse effects of TERT-CLPTM1L and double-strand breaks repair contribute to risk for nasopharyngeal carcinoma Cancer Research. 74: 4148-4148. DOI: 10.1158/1538-7445.Am2014-4148  0.314
2014 Cheng WW, Ngan RKC, Kwong DLW, Huang THM, Ma VWS, Law SCK, Tse L, Busson P, Tsao GSW, Lung ML, Yip TTC. Abstract 2298: Methylated gene markers discovered in nasopharyngeal carcinoma by differential methylation hybridization (DMH) in high density CpG island DNA chips Cancer Research. 74: 2298-2298. DOI: 10.1158/1538-7445.Am2014-2298  0.431
2014 Cheng Y, Phoon YP, Lung ML. Abstract 1938: Inhibition of both physiological and aberrant Wnt/β-catenin signaling activities associated with stemness in nasopharyngeal carcinoma Cancer Research. 74: 1938-1938. DOI: 10.1158/1538-7445.Am2014-1938  0.541
2014 Lung HL, Lung ML. Abstract 1150: The role of the tumor suppressor geneTHY1in suppression of epithelial-mesenchymal transition (EMT) in nasopharyngeal carcinoma Cancer Research. 74: 1150-1150. DOI: 10.1158/1538-7445.Am2014-1150  0.522
2013 Chan KC, Ting CM, Chan PS, Lo MC, Lo KW, Curry JE, Smyth T, Lee AW, Ng WT, Tsao GS, Wong RN, Lung ML, Mak NK. A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation. Molecular Cancer. 12: 128. PMID 24156782 DOI: 10.1186/1476-4598-12-128  0.499
2013 Cheng Y, Cheung AK, Ko JM, Phoon YP, Chiu PM, Lo PH, Waterman ML, Lung ML. Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma. Bmc Cell Biology. 14: 44. PMID 24073846 DOI: 10.1186/1471-2121-14-44  0.508
2013 Cheung AK, Ip JC, Lung HL, Wu JZ, Tsao SW, Lung ML. Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma. Molecular Cancer Therapeutics. 12: 1393-401. PMID 23686835 DOI: 10.1158/1535-7163.Mct-12-1219  0.476
2013 Zhang G, Tsang CM, Deng W, Yip YL, Lui VW, Wong SC, Cheung AL, Hau PM, Zeng M, Lung ML, Chen H, Lo KW, Takada K, Tsao SW. Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells. Plos One. 8: e62284. PMID 23658720 DOI: 10.1371/Journal.Pone.0062284  0.302
2013 Lo MC, Yip TC, Ngan KC, Cheng WW, Law CK, Chan PS, Chan KC, Wong CK, Wong RN, Lo KW, Ng WT, Lee WM, Tsao SW, Kwong LW, Lung ML, et al. Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres. Cancer Letters. 335: 81-92. PMID 23403077 DOI: 10.1016/J.Canlet.2013.01.052  0.5
2013 Tang KH, Dai YD, Tong M, Chan YP, Kwan PS, Fu L, Qin YR, Tsao SW, Lung HL, Lung ML, Tong DK, Law S, Chan KW, Ma S, Guan XY. A CD90(+) tumor-initiating cell population with an aggressive signature and metastatic capacity in esophageal cancer. Cancer Research. 73: 2322-32. PMID 23382045 DOI: 10.1158/0008-5472.Can-12-2991  0.482
2013 Kan R, Cheung AKL, Lung ML. Abstract A26: Tumor-suppressive LTBP2 is associated with NF-kB signaling pathway regulation in nasopharyngeal carcinoma Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A26  0.514
2013 Shuen WH, Lung ML. Abstract 4309: Fibulin-2 suppresses tumor growth and angiogenesis through the inhibition of Erk1/2 and p65 pathways in nasopharyngeal carcinoma. Cancer Research. 73: 4309-4309. DOI: 10.1158/1538-7445.Am2013-4309  0.546
2013 Yang X, Szeto YY, Cheng Y, Kwong DL, Lung ML. Abstract 3555: Identification of candidate epigenetic markers for early detection of nasopharyngeal carcinoma. Cancer Research. 73: 3555-3555. DOI: 10.1158/1538-7445.Am2013-3555  0.572
2012 Tsang CM, Yip YL, Lo KW, Deng W, To KF, Hau PM, Lau VM, Takada K, Lui VW, Lung ML, Chen H, Zeng M, Middeldorp JM, Cheung AL, Tsao SW. Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 109: E3473-82. PMID 23161911 DOI: 10.1073/Pnas.1202637109  0.358
2012 Chen H, Ko JM, Wong VC, Hyytiainen M, Keski-Oja J, Chua D, Nicholls JM, Cheung FM, Lee AW, Kwong DL, Chiu PM, Zabarovsky ER, Tsao SW, Tao Q, Kan R, ... ... Lung ML, et al. LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma. Cancer Letters. 325: 89-98. PMID 22743615 DOI: 10.1016/J.Canlet.2012.06.005  0.544
2012 Lung ML. Unlocking the Rosetta Stone enigma for nasopharyngeal carcinoma: Genetics, viral infection, and epidemiological factors Seminars in Cancer Biology. 22: 77-78. PMID 22266061 DOI: 10.1016/J.Semcancer.2012.01.006  0.309
2012 Huang Z, Cheng Y, Chiu PM, Cheung FM, Nicholls JM, Kwong DL, Lee AW, Zabarovsky ER, Stanbridge EJ, Lung HL, Lung ML. Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties. Oncogene. 31: 3709-20. PMID 22158051 DOI: 10.1038/Onc.2011.529  0.614
2012 Lung HL, Cheung AK, Ko JM, Cheng Y, Stanbridge EJ, Lung ML. Deciphering the molecular genetic basis of NPC through functional approaches. Seminars in Cancer Biology. 22: 87-95. PMID 22154888 DOI: 10.1016/J.Semcancer.2011.11.002  0.589
2012 Lo PH, Ko JM, Yu ZY, Law S, Wang LD, Li JL, Srivastava G, Tsao SW, Stanbridge EJ, Lung ML. The LIM domain protein, CRIP2, promotes apoptosis in esophageal squamous cell carcinoma. Cancer Letters. 316: 39-45. PMID 22154084 DOI: 10.1016/J.Canlet.2011.10.020  0.416
2012 Ting CM, Wong CK, Wong RN, Lo KW, Lee AW, Tsao GS, Lung ML, Mak NK. Role of STAT3/5 and Bcl-2/xL in 2-methoxyestradiol-induced endoreduplication of nasopharyngeal carcinoma cells. Molecular Carcinogenesis. 51: 963-72. PMID 22006341 DOI: 10.1002/Mc.20867  0.424
2012 Law EW, Cheung AK, Kashuba VI, Pavlova TV, Zabarovsky ER, Lung HL, Cheng Y, Chua D, Lai-Wan Kwong D, Tsao SW, Sasaki T, Stanbridge EJ, Lung ML. Anti-angiogenic and tumor-suppressive roles of candidate tumor-suppressor gene, Fibulin-2, in nasopharyngeal carcinoma. Oncogene. 31: 728-38. PMID 21743496 DOI: 10.1038/Onc.2011.272  0.661
2012 Wong VCL, Chen H, Ko JMY, Chan KW, Chan YP, Law S, Chua D, Kwong DLW, Lung HL, Srivastava G, Tang JCO, Tsao SW, Zabarovsky ER, Stanbridge EJ, Lung ML. Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype International Journal of Cancer. 130: 83-95. PMID 21387288 DOI: 10.1002/Ijc.25970  0.549
2012 Cheng Y, Cheung AKL, Ko JMY, Phoon YP, Lung ML. Abstract 420: Physiological β-catenin signaling regulates pluripotency genes in cancer microcell hybrids Cancer Research. 72: 420-420. DOI: 10.1158/1538-7445.Am2012-420  0.553
2012 Cheung AK, Lung HL, Ko JM, Ip JC, Zabarovsky E, Stanbridge EJ, Lung ML. Abstract 4002: Functional investigation and identification of dephosphorylation targets of tumor-suppressive protein tyrosine phosphatase, PTPRG Cancer Research. 72: 4002-4002. DOI: 10.1158/1538-7445.Am2012-4002  0.409
2012 Lung HL, Cheung AKL, Chung YM, Liu ET, Chua D, Lung ML. Abstract 3998: The role of serum amyloid A1 (SAA1) in nasopharyngeal carcinoma (NPC) Cancer Research. 72: 3998-3998. DOI: 10.1158/1538-7445.Am2012-3998  0.535
2012 Yu Z, Wong VCL, Chan KW, Lung ML. Abstract 3996: Identification of DEC1-interacting protein DNAJB6 and its role in esophageal squamous cell carcinoma Cancer Research. 72: 3996-3996. DOI: 10.1158/1538-7445.Am2012-3996  0.484
2012 Josephine MYK, Wang LD, Song X, Song YQ, Lung ML. Abstract 2637: Application of identity-by-descent (IBD) approach to genetic mapping of susceptibility locus in hereditary esophageal squamous cell carcinoma (ESCC) by high density SNP array analysis Cancer Research. 72: 2637-2637. DOI: 10.1158/1538-7445.Am2012-2637  0.344
2012 Cheung WY, Ko JMY, Yu Z, Lung ML. Abstract 2181: Characterization of PHF11, a candidate tumor suppressor gene, in esophageal squamous cell carcinoma Cancer Research. 72: 2181-2181. DOI: 10.1158/1538-7445.Am2012-2181  0.514
2011 Cheung AKL, Ko JMY, Lung HL, Chan KW, Stanbridge EJ, Zabarovsky E, Tokino T, Kashima L, Suzuki T, Kwong DLW, Chua D, Tsao SW, Lung ML. Cysteine-rich intestinal protein 2 (CRIP2) acts as a repressor of NF-κB-mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis Proceedings of the National Academy of Sciences of the United States of America. 108: 8390-8395. PMID 21540330 DOI: 10.1073/Pnas.1101747108  0.525
2011 Wong VCL, Ko JMY, Qi RZ, Li PJ, Wang LD, Li JL, Chan YP, Chan KW, Stanbridge EJ, Lung ML. Abrogated expression of DEC1 during oesophageal squamous cell carcinoma progression is age- and family history-related and significantly associated with lymph node metastasis British Journal of Cancer. 104: 841-849. PMID 21326238 DOI: 10.1038/Bjc.2011.25  0.4
2011 Chan KC, Ko JM, Lung HL, Sedlacek R, Zhang ZF, Luo DZ, Feng ZB, Chen S, Chen H, Chan KW, Tsao SW, Chua DT, Zabarovsky ER, Stanbridge EJ, Lung ML. Catalytic activity of Matrix metalloproteinase-19 is essential for tumor suppressor and anti-angiogenic activities in nasopharyngeal carcinoma. International Journal of Cancer. Journal International Du Cancer. 129: 1826-37. PMID 21165953 DOI: 10.1002/Ijc.25855  0.378
2011 Chan SH, Yee Ko JM, Chan KW, Chan YP, Tao Q, Hyytiainen M, Keski-Oja J, Law S, Srivastava G, Tang J, Tsao SW, Chen H, Stanbridge EJ, Lung ML. The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome. International Journal of Cancer. Journal International Du Cancer. 129: 565-73. PMID 20878956 DOI: 10.1002/Ijc.25698  0.563
2010 Yip YL, Tsang CM, Deng W, Cheung PY, Jin Y, Cheung AL, Lung ML, Tsao SW. Expression of Epstein-Barr virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. Journal of Medical Virology. 82: 1711-23. PMID 20827769 DOI: 10.1002/Jmv.21875  0.455
2010 Lo PH, Lung HL, Cheung AK, Apte SS, Chan KW, Kwong FM, Ko JM, Cheng Y, Law S, Srivastava G, Zabarovsky ER, Tsao SW, Tang JC, Stanbridge EJ, Lung ML. Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis. Cancer Research. 70: 5567-76. PMID 20551050 DOI: 10.1158/0008-5472.Can-09-4510  0.679
2010 Lung HL, Cheung AK, Cheng Y, Kwong FM, Lo PH, Law EW, Chua D, Zabarovsky ER, Wang N, Tsao SW, Stanbridge EJ, Lung ML. Functional characterization of THY1 as a tumor suppressor gene with antiinvasive activity in nasopharyngeal carcinoma. International Journal of Cancer. Journal International Du Cancer. 127: 304-12. PMID 19921696 DOI: 10.1002/Ijc.25047  0.672
2010 Ting CM, Lee YM, Wong CK, Wong AS, Lung HL, Lung ML, Lo KW, Wong RN, Mak NK. 2-Methoxyestradiol induces endoreduplication through the induction of mitochondrial oxidative stress and the activation of MAPK signaling pathways. Biochemical Pharmacology. 79: 825-41. PMID 19883629 DOI: 10.1016/J.Bcp.2009.10.018  0.345
2010 Wong VC, Qi RZ, Chan KW, Li PJ, Wang LD, Li JL, Law S, Tsao SW, Lung ML. Abstract 5008: Loss of DEC1 (Deleted in esophageal cancer 1) during esophageal cancer progression and functional characterization of its downstream target Cancer Research. 70: 5008-5008. DOI: 10.1158/1538-7445.Am10-5008  0.517
2010 Cheung AKL, Lung HL, Ko JMY, Lung ML. Abstract 3080: Functional studies of a cell cycle and angiogenesis-related candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma Cancer Research. 70: 3080-3080. DOI: 10.1158/1538-7445.Am10-3080  0.553
2010 Chi CK, Ko JMY, Lung HL, Sedlacek R, Lung ML. Abstract 3069: Importance of zinc-binding domain ofmatrix metalloproteinase 19(MMP19) in tumor suppression and anti-angiogenesis of nasopharyngeal carcinoma Cancer Research. 70: 3069-3069. DOI: 10.1158/1538-7445.Am10-3069  0.392
2010 Ko JMY, Cheung AK, Lung ML. Abstract 3061: Tumor suppressive and angiogenic role ofTHSD1in esophageal squamous cell carcinoma and nasopharyngeal carcinoma Cancer Research. 70: 3061-3061. DOI: 10.1158/1538-7445.Am10-3061  0.599
2010 Lung HL, Lo PHY, Cheung AKL, Apte SS, Lung ML. Abstract 3058:ADAMTS9inhibits angiogenesis and induces apoptosis in nasopharyngeal carcinoma Cancer Research. 70: 3058-3058. DOI: 10.1158/1538-7445.Am10-3058  0.431
2009 Koon HK, Chan PS, Wong RNS, Wu ZG, Lung ML, Chang CK, Mak NK. Targeted inhibition of the EGFR pathways enhances Zn-BC-AM PDT-induced apoptosis in well-differentiated nasopharyngeal carcinoma cells Journal of Cellular Biochemistry. 108: 1356-1363. PMID 19816982 DOI: 10.1002/Jcb.22366  0.327
2009 Cheung AK, Lung HL, Ko JM, Cheng Y, Stanbridge EJ, Zabarovsky ER, Nicholls JM, Chua D, Tsao SW, Guan XY, Lung ML. Chromosome 14 transfer and functional studies identify a candidate tumor suppressor gene, mirror image polydactyly 1, in nasopharyngeal carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 106: 14478-83. PMID 19667180 DOI: 10.1073/Pnas.0900198106  0.659
2009 Chan PS, Koon HK, Wu ZG, Wong RNS, Lung ML, Chang CK, Mak NK. Role of p38 mapks in hypericin photodynamic therapy-induced apoptosis of nasopharyngeal carcinoma cells Photochemistry and Photobiology. 85: 1207-1217. PMID 19496992 DOI: 10.1111/J.1751-1097.2009.00572.X  0.342
2008 Cheung AK, Lung HL, Hung SC, Law EW, Cheng Y, Yau WL, Bangarusamy DK, Miller LD, Liu ET, Shao JY, Kou CW, Chua D, Zabarovsky ER, Tsao SW, Stanbridge EJ, ... Lung ML, et al. Functional analysis of a cell cycle-associated, tumor-suppressive gene, protein tyrosine phosphatase receptor type G, in nasopharyngeal carcinoma. Cancer Research. 68: 8137-45. PMID 18829573 DOI: 10.1158/0008-5472.Can-08-0904  0.678
2008 Wong VC, Chan PL, Bernabeu C, Law S, Wang LD, Li JL, Tsao SW, Srivastava G, Lung ML. Identification of an invasion and tumor-suppressing gene, Endoglin (ENG), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma. International Journal of Cancer. 123: 2816-23. PMID 18798555 DOI: 10.1002/Ijc.23882  0.572
2008 Lee YM, Ting CM, Cheng YK, Fan TP, Wong RN, Lung ML, Mak NK. Mechanisms of 2-methoxyestradiol-induced apoptosis and G2/M cell-cycle arrest of nasopharyngeal carcinoma cells. Cancer Letters. 268: 295-307. PMID 18492602 DOI: 10.1016/J.Canlet.2008.04.010  0.505
2008 Lee KY, Geng H, Ng KM, Yu J, van Hasselt A, Cao Y, Zeng YX, Wong AH, Wang X, Ying J, Srivastava G, Lung ML, Wang LD, Kwok TT, Levi BZ, et al. Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas. Oncogene. 27: 5267-76. PMID 18469857 DOI: 10.1038/Onc.2008.147  0.548
2008 Lung HL, Lo PH, Xie D, Apte SS, Cheung AK, Cheng Y, Law EW, Chua D, Zeng YX, Tsao SW, Stanbridge EJ, Lung ML. Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9, and its association with lymph node metastases in nasopharyngeal carcinoma. International Journal of Cancer. Journal International Du Cancer. 123: 401-8. PMID 18449890 DOI: 10.1002/Ijc.23528  0.666
2008 Ko JM, Chan PL, Yau WL, Chan HK, Chan KC, Yu ZY, Kwong FM, Miller LD, Liu ET, Yang LC, Lo PH, Stanbridge EJ, Tang JC, Srivastava G, Tsao SW, ... ... Lung ML, et al. Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma. Molecular Cancer Research : McR. 6: 592-603. PMID 18403638 DOI: 10.1158/1541-7786.Mcr-07-0154  0.707
2008 Lung HL, Lo CC, Wong CC, Cheung AK, Cheong KF, Wong N, Kwong FM, Chan KC, Law EW, Tsao SW, Chua D, Sham JS, Cheng Y, Stanbridge EJ, Robertson GP, ... Lung ML, et al. Identification of tumor suppressive activity by irradiation microcell-mediated chromosome transfer and involvement of alpha B-crystallin in nasopharyngeal carcinoma. International Journal of Cancer. Journal International Du Cancer. 122: 1288-96. PMID 18027848 DOI: 10.1002/Ijc.23259  0.592
2008 Leung AC, Wong VC, Yang LC, Chan PL, Daigo Y, Nakamura Y, Qi RZ, Miller LD, Liu ET, Wang LD, Li JL, Law S, Tsao SW, Lung ML. Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma. International Journal of Cancer. 122: 587-94. PMID 17943723 DOI: 10.1002/Ijc.23144  0.74
2007 Lo PH, Xie D, Chan KC, Xu FP, Kuzmin I, Lerman MI, Law S, Chua D, Sham J, Lung ML. Reduced expression of RASSF1A in esophageal and nasopharyngeal carcinomas significantly correlates with tumor stage. Cancer Letters. 257: 199-205. PMID 17720308 DOI: 10.1016/J.Canlet.2007.07.018  0.528
2007 Jin H, Wang X, Ying J, Wong AH, Li H, Lee KY, Srivastava G, Chan AT, Yeo W, Ma BB, Putti TC, Lung ML, Shen ZY, Xu LY, Langford C, et al. Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas. Oncogene. 26: 7490-8. PMID 17546048 DOI: 10.1038/Sj.Onc.1210559  0.564
2007 Zhang H, Liao LH, Liu SM, Lau KW, Lai AK, Zhang JH, Wang Q, Chen XQ, Wei W, Liu H, Cai JH, Lung ML, Tai SS, Wu M. Microsomal glutathione S-transferase gene polymorphisms and colorectal cancer risk in a Han Chinese population. International Journal of Colorectal Disease. 22: 1185-94. PMID 17483957 DOI: 10.1007/S00384-007-0308-9  0.302
2007 Kost-Alimova M, Darai-Ramqvist E, Yau WL, Sandlund A, Fedorova L, Yang Y, Kholodnyuk I, Cheng Y, Lung ML, Stanbridge E, Klein G, Imreh S. Mandatory chromosomal segment balance in aneuploid tumor cells Bmc Cancer. 7. PMID 17257397 DOI: 10.1186/1471-2407-7-21  0.619
2007 Lo PH, Leung AC, Kwok CY, Cheung WS, Ko JM, Yang LC, Law S, Wang LD, Li J, Stanbridge EJ, Srivastava G, Tang JC, Tsao SW, Lung ML. Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9. Oncogene. 26: 148-57. PMID 16799631 DOI: 10.1038/Sj.Onc.1209767  0.72
2006 Li KM, Sun X, Koon HK, Leung WN, Fung MC, Wong RN, Lung ML, Chang CK, Mak NK. Apoptosis and expression of cytokines triggered by pyropheophorbide-a methyl ester-mediated photodynamic therapy in nasopharyngeal carcinoma cells. Photodiagnosis and Photodynamic Therapy. 3: 247-58. PMID 25046989 DOI: 10.1016/J.Pdpdt.2006.09.001  0.37
2006 Lung HL, Cheung AK, Xie D, Cheng Y, Kwong FM, Murakami Y, Guan XY, Sham JS, Chua D, Protopopov AI, Zabarovsky ER, Tsao SW, Stanbridge EJ, Lung ML. TSLC1 is a tumor suppressor gene associated with metastasis in nasopharyngeal carcinoma. Cancer Research. 66: 9385-92. PMID 17018592 DOI: 10.1158/0008-5472.Can-06-0590  0.651
2006 Yau WL, Lung HL, Zabarovsky ER, Lerman MI, Sham JS, Chua DT, Tsao SW, Stanbridge EJ, Lung ML. Functional studies of the chromosome 3p21.3 candidate tumor suppressor gene BLU/ZMYND10 in nasopharyngeal carcinoma. International Journal of Cancer. Journal International Du Cancer. 119: 2821-6. PMID 16929489 DOI: 10.1002/Ijc.22232  0.536
2006 Yi Lo PH, Chung Leung AC, Xiong W, Law S, Duh FM, Lerman MI, Stanbridge EJ, Lung ML. Expression of candidate chromosome 3p21.3 tumor suppressor genes and down-regulation of BLU in some esophageal squamous cell carcinomas. Cancer Letters. 234: 184-92. PMID 15885884 DOI: 10.1016/J.Canlet.2005.03.036  0.552
2005 Lung HL, Bangarusamy DK, Xie D, Cheung AK, Cheng Y, Kumaran MK, Miller L, Liu ET, Guan XY, Sham JS, Fang Y, Li L, Wang N, Protopopov AI, Zabarovsky ER, ... ... Lung ML, et al. THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma. Oncogene. 24: 6525-32. PMID 16007174 DOI: 10.1038/Sj.Onc.1208812  0.585
2005 Ko JM, Yau WL, Chan PL, Lung HL, Yang L, Lo PH, Tang JC, Srivastava G, Stanbridge EJ, Lung ML. Functional evidence of decreased tumorigenicity associated with monochromosome transfer of chromosome 14 in esophageal cancer and the mapping of tumor-suppressive regions to 14q32. Genes, Chromosomes & Cancer. 43: 284-93. PMID 15834943 DOI: 10.1002/Gcc.20190  0.669
2005 Yang L, Leung AC, Ko JM, Lo PH, Tang JC, Srivastava G, Oshimura M, Stanbridge EJ, Daigo Y, Nakamura Y, Tang CM, Lau KW, Law S, Lung ML. Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma. Oncogene. 24: 697-705. PMID 15580306 DOI: 10.1038/Sj.Onc.1208179  0.712
2004 Yang LC, Tang JC, Srivastava G, Stanbridge EJ, Lung ML. Functional investigation of tumor suppressive role of chromosome 9 in esophageal squamous cell carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 9571. PMID 28016658 DOI: 10.1200/Jco.2004.22.14_Suppl.9571  0.45
2004 Mak NK, Li KM, Leung WN, Wong RNS, Huang DP, Lung ML, Lau YK, Chang CK. Involvement of both endoplasmic reticulum and mitochondria in photokilling of nasopharyngeal carcinoma cells by the photosensitizer Zn-BC-AM Biochemical Pharmacology. 68: 2387-2396. PMID 15548385 DOI: 10.1016/J.Bcp.2004.08.024  0.312
2004 Lung HL, Cheng Y, Kumaran MK, Liu ET, Murakami Y, Chan CY, Yau WL, Ko JM, Stanbridge EJ, Lung ML. Fine mapping of the 11q22-23 tumor suppressive region and involvement of TSLC1 in nasopharyngeal carcinoma. International Journal of Cancer. Journal International Du Cancer. 112: 628-35. PMID 15382043 DOI: 10.1002/Ijc.20454  0.623
2004 Kwong FM, Tang JCO, Srivastava G, Lung ML. Inactivation mechanisms and growth suppressive effects of p16INK4a in Asian esophageal squamous carcinoma cell lines Cancer Letters. 208: 207-213. PMID 15142680 DOI: 10.1016/J.Canlet.2003.11.017  0.444
2004 Chan KT, Lung ML. Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line. Cancer Chemotherapy and Pharmacology. 53: 519-26. PMID 15004724 DOI: 10.1007/S00280-004-0767-4  0.355
2004 Lichun Y, Ching Tang CM, Wai Lau K, Lung ML. Frequent loss of heterozygosity on chromosome 9 in Chinese esophageal squamous cell carcinomas. Cancer Letters. 203: 71-7. PMID 14670619 DOI: 10.1016/J.Canlet.2003.09.027  0.414
2003 Cheng Y, Ko JM, Lung HL, Lo PH, Stanbridge EJ, Lung ML. Monochromosome transfer provides functional evidence for growth-suppressive genes on chromosome 14 in nasopharyngeal carcinoma. Genes, Chromosomes & Cancer. 37: 359-68. PMID 12800147 DOI: 10.1002/Gcc.10228  0.58
2003 Kwong FM, Wong PS, Lung ML. Genetic alterations detected on chromosomes 13 and 14 in Chinese non-small cell lung carcinomas. Cancer Letters. 192: 189-98. PMID 12668283 DOI: 10.1016/S0304-3835(02)00698-5  0.369
2002 Cheng Y, Chakrabarti R, Garcia-Barcelo M, Ha TJ, Srivatsan ES, Stanbridge EJ, Lung ML. Mapping of nasopharyngeal carcinoma tumor-suppressive activity to a 1.8-megabase region of chromosome band 11q13. Genes, Chromosomes & Cancer. 34: 97-103. PMID 11921287 DOI: 10.1002/Gcc.10048  0.626
2002 Lam CT, Tang CM, Lau KW, Lung ML. Loss of heterozygosity on chromosome 11 in esophageal squamous cell carcinomas. Cancer Letters. 178: 75-81. PMID 11849744 DOI: 10.1016/S0304-3835(01)00814-X  0.446
2001 Ko JM, Wong CP, Tang CM, Lau KW, Lung ML. Frequent loss of heterozygosity on multiple chromosomes in Chinese esophageal squamous cell carcinomas. Cancer Letters. 170: 131-8. PMID 11463490 DOI: 10.1016/S0304-3835(01)00577-8  0.377
2000 Cheng Y, Stanbridge EJ, Kong H, Bengtsson U, Lerman MI, Lung ML. A functional investigation of tumor suppressor gene activities in a nasopharyngeal carcinoma cell line HONE1 using a monochromosome transfer approach. Genes, Chromosomes & Cancer. 28: 82-91. PMID 10738306 DOI: 10.1002/(Sici)1098-2264(200005)28:1<82::Aid-Gcc10>3.0.Co;2-8  0.631
1999 Ko JM, Cheung MH, Kwan MW, Wong CM, Lau KW, Tang CM, Lung ML. Genomic instability and alterations in Apc, Mcc and Dcc in Hong Kong patients with colorectal carcinoma. International Journal of Cancer. Journal International Du Cancer. 84: 404-9. PMID 10404094 DOI: 10.1002/(Sici)1097-0215(19990820)84:4<404::Aid-Ijc13>3.0.Co;2-L  0.465
1999 Ko JM, Cheung MH, Wong C, Lau K, Tang CM, Kwan MW, Lung ML. L-myc genotypes in Hong Kong Chinese colorectal carcinoma patients. Oncology Reports. 6: 441-4. PMID 10023018 DOI: 10.3892/Or.6.2.441  0.323
1999 Chan WC, Leung CS, Lung ML. Comparative p53 mutational spectra in aerodigestive tract tumors in Hong Kong Chinese patients. Oncology Reports. 6: 167-239. DOI: 10.3892/Or.6.1.167  0.371
1998 Lung ML, Hu Y, Cheng Y, Li MF, Tang CM, O SK, Iggo RD. p53 inactivating mutations in Chinese nasopharyngeal carcinomas. Cancer Letters. 133: 89-94. PMID 9929165 DOI: 10.1016/S0304-3835(98)00209-2  0.493
1998 Ge H, Wong MP, Lam WK, Lee J, Fu KH, Yew WW, Lung ML. p53 intron 2 genotypes detected in normal specimens and lung carcinomas in Hong Kong. Oncology Reports. 5: 1265-7. PMID 9683848 DOI: 10.3892/Or.5.5.1265  0.344
1998 Cheng Y, Poulos NE, Lung ML, Hampton G, Ou B, Lerman MI, Stanbridge EJ. Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3. Proceedings of the National Academy of Sciences of the United States of America. 95: 3042-7. PMID 9501212 DOI: 10.1073/Pnas.95.6.3042  0.633
1998 Lam W, Ge H, Wong M, Lee J, Fu K, Yew W, Lung M. Polymorphisms and mutatons detected in P53 exon 2 and intron 2 in lung carcinomas in Hong Kong Chest. DOI: 10.1378/Chest.114.4_Supplement.249S  0.33
1997 Chan WC, Tang CM, Lau KW, Lung ML. p16 tumor suppressor gene mutations in Chinese esophageal carcinomas in Hong Kong. Cancer Letters. 115: 201-6. PMID 9149125 DOI: 10.1016/S0304-3835(97)04748-4  0.377
1996 Ge H, Lam WK, Lee J, Wong MP, Yew WW, Lung ML. Analysis of L-myc and GSTM1 genotypes in Chinese non-small cell lung carcinoma patients. Lung Cancer (Amsterdam, Netherlands). 15: 355-66. PMID 8959680 DOI: 10.1016/0169-5002(95)00598-6  0.333
1996 Chan AS, Lam WK, Wong MP, Fu KH, Lee J, Yew WW, Chiu SW, Lung ML. Chromosomal 11 alterations in non-small-cell lung carcinomas in Hong Kong. Lung Cancer (Amsterdam, Netherlands). 15: 51-65. PMID 8865123 DOI: 10.1016/0169-5002(96)00570-3  0.344
1996 Lung ML, Wong MP, Skaanild MT, Fok CL, Lam WK, Yew WW. p53 mutations in non-small cell lung carcinomas in Hong Kong. Chest. 109: 718-26. PMID 8617082 DOI: 10.1378/Chest.109.3.718  0.405
1996 Ge H, Lam WK, Lee J, Wong MP, Fu KH, Yew WW, Lung ML. Detection and evaluation of p53 intron 2 polymorphism in lung carcinomas in Hong Kong. International Journal of Cancer. Journal International Du Cancer. 69: 120-4. PMID 8608979 DOI: 10.1002/(Sici)1097-0215(19960422)69:2<120::Aid-Ijc9>3.0.Co;2-2  0.319
1993 Lung ML, Sham JST, Lam WP, Choy DTK. Analysis of Epstein-Barr virus in localized nasopharyngeal carcinoma tumors Cancer. 71: 1190-1192. PMID 8382103 DOI: 10.1002/1097-0142(19930215)71:4<1190::Aid-Cncr2820710403>3.0.Co;2-B  0.426
1992 Lung ML, Wong M, Lam WK, Lau KS, Kwan S, Fu KH, Cheung H, Yew WW. Incidence of ras oncogene activation in lung carcinomas in Hong Kong. Cancer. 70: 760-3. PMID 1322782 DOI: 10.1002/1097-0142(19920815)70:4<760::Aid-Cncr2820700407>3.0.Co;2-0  0.31
1990 Lung ML, Chang RS, Huang ML, Guo H, Choy D, Sham J, Tsao SY, Cheng P, Ng MH. Epstein-Barr virus genotypes associated with nasopharyngeal carcinoma in Southern China Virology. 177: 44-53. PMID 2162115 DOI: 10.1016/0042-6822(90)90458-4  0.369
1989 Lung ML, Chan KH, Lam WP, Kou SK, Choy D, Chan CW, Ng MH. In situ detection of Epstein-Barr virus markers in nasopharyngeal carcinoma patients. Oncology. 46: 310-317. PMID 2550863 DOI: 10.1159/000226739  0.358
1985 Lung ML, So SY, Chan KH, Lam WK, Lam WP, Ng MH. Evidence that respiratory tract is major reservoir for Epstein-Barr virus. The Lancet. 325: 889-892. PMID 2858744 DOI: 10.1016/S0140-6736(85)91671-X  0.324
1980 Lung ML, Hering C, Hartley JW, Rowe WP, Hopkins N. Analysis of the genomes of mink cell focus-inducing murine type-C viruses: a progress report. Cold Spring Harbor Symposia On Quantitative Biology. 44: 1269-74. PMID 6253201 DOI: 10.1101/Sqb.1980.044.01.138  0.305
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