Andrew L. Mellor - Publications

Affiliations: 
Medical College of Georgia, Augusta, GA, United States 
Area:
Immunology, Cell Biology

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wu Y, Tang CA, Mealer C, Bastian D, Hanief Sofi M, Tian L, Schutt S, Choi HJ, Ticer T, Zhang M, Sui X, Huang L, Mellor AL, Hu CA, Yu XZ. STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function. Cellular & Molecular Immunology. PMID 33500563 DOI: 10.1038/s41423-020-00611-6  0.411
2020 Zhou C, Zhang Y, Yan R, Huang L, Mellor AL, Yang Y, Chen X, Wei W, Wu X, Yu L, Liang L, Zhang D, Wu S, Wang W. Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment. Cell Death and Differentiation. PMID 32929219 DOI: 10.1038/S41418-020-00618-6  0.396
2020 Lemos H, Ou R, McCardle C, Lin Y, Calver J, Minett J, Chadli A, Huang L, Mellor AL. Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity. Journal For Immunotherapy of Cancer. 8. PMID 32847988 DOI: 10.1136/Jitc-2020-001182  0.375
2020 Lemos H, Mohamed E, Ou R, McCardle C, Zheng X, McGuire K, Homer NZM, Mole DJ, Huang L, Mellor AL. Co-treatments to Boost IDO Activity and Inhibit Production of Downstream Catabolites Induce Durable Suppression of Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology. 11: 1256. PMID 32625215 DOI: 10.3389/Fimmu.2020.01256  0.393
2020 Zhang Y, Wang N, Ding M, Yang Y, Wang Z, Huang L, Zhu W, Mellor AL, Hou X, Zhou C, Yan R, Wang W, Wu S. CD40 Accelerates the Antigen-Specific Stem-Like Memory CD8 T Cells Formation and Human Papilloma Virus (HPV)-Positive Tumor Eradication. Frontiers in Immunology. 11: 1012. PMID 32536922 DOI: 10.3389/Fimmu.2020.01012  0.429
2020 Yu M, Guo G, Huang L, Deng L, Chang CS, Achyut BR, Canning M, Xu N, Arbab AS, Bollag RJ, Rodriguez PC, Mellor AL, Shi H, Munn DH, Cui Y. CD73 on cancer-associated fibroblasts enhanced by the A-mediated feedforward circuit enforces an immune checkpoint. Nature Communications. 11: 515. PMID 31980601 DOI: 10.1038/S41467-019-14060-X  0.443
2019 Lemos H, Mohamed E, Huang L, Chandler PR, Ou R, Pacholczyk R, Mellor AL. Stimulator of Interferon Genes Agonists attenuate type I diabetes progression in NOD mice. Immunology. PMID 31557322 DOI: 10.1111/Imm.13122  0.356
2019 Davison LM, Liu JC, Huang L, Carroll TM, Mellor AL, Jørgensen TN. Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice. Frontiers in Immunology. 10: 2017. PMID 31555267 DOI: 10.3389/Fimmu.2019.02017  0.389
2019 Jiang X, Xu J, Liu M, Xing H, Wang Z, Huang L, Mellor AL, Wang W, Wu S. Adoptive CD8+ T cell therapy against cancer:Challenges and opportunities. Cancer Letters. PMID 31356845 DOI: 10.1016/J.Canlet.2019.07.017  0.511
2019 Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LMF, Pigott E, Keough MP, Rust S, Mellor AL, Mandik-Nayak L, Muller AJ, Prendergast GC. IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation. International Immunology. 31: 181-182. PMID 31222337 DOI: 10.1093/Intimm/Dxz003  0.438
2019 Lemos H, Huang L, Prendergast GC, Mellor AL. Immune control by amino acid catabolism during tumorigenesis and therapy. Nature Reviews. Cancer. PMID 30696923 DOI: 10.1038/S41568-019-0106-Z  0.442
2019 Mellor AL, Huang L. Metabolic requirements for expanding and arming a clone army. Nature Immunology. 20: 118-120. PMID 30664763 DOI: 10.1038/S41590-018-0299-4  0.32
2019 Lin DJ, Ng JC, Huang L, Robinson M, O'Hara J, Wilson JA, Mellor AL. Abstract LB-184: The immunotherapeutic role of indoleamine 2,3-dioxygenase (IDO) in head and neck squamous cell carcinoma: a systematic review Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-184  0.38
2018 Yu M, Guo G, Huang L, Deng L, Bollag R, Mellor A, Shi H, Cui Y. Abstract LB-282: Dynamic regulation of CD73 expression in cancer associated fibroblasts enforces immunosuppression via a feedforward adenosinergic pathway Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-282  0.441
2017 Mellor AL, Lemos H, Huang L. Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now? Frontiers in Immunology. 8: 1360. PMID 29163470 DOI: 10.3389/Fimmu.2017.01360  0.491
2017 Zhu H, Lemos H, Bhatt B, Islam BN, Singh A, Gurav A, Huang L, Browning DD, Mellor A, Fulzele S, Singh N. Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity. Plos One. 12: e0183484. PMID 28898256 DOI: 10.1371/Journal.Pone.0183484  0.43
2017 Horvatinovich JM, Grogan EW, Norris M, Steinkasserer A, Lemos H, Mellor AL, Tcherepanova IY, Nicolette CA, DeBenedette MA. Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14(+) Monocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 28193829 DOI: 10.4049/Jimmunol.1600802  0.508
2016 Huang L, Ou R, Rabelo de Souza G, Cunha TM, Lemos H, Mohamed E, Li L, Pacholczyk G, Randall J, Munn DH, Mellor AL. Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase. Plos Pathogens. 12: e1005615. PMID 27168185 DOI: 10.1371/Journal.Ppat.1005615  0.409
2016 Hong Y, Manoharan I, Suryawanshi A, Shanmugam A, Swafford D, Ahmad S, Chinnadurai R, Manicassamy B, He Y, Mellor AL, Thangaraju M, Munn DH, Manicassamy S. Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity. Oncoimmunology. 5: e1115941. PMID 27141399 DOI: 10.1080/2162402X.2015.1115941  0.498
2016 Lemos H, Mohamed E, Huang L, Ou R, Pacholczyk G, Arbab AS, Munn D, Mellor AL. STING promotes the growth of tumors characterized by low antigenicity via IDO activation. Cancer Research. PMID 26964621 DOI: 10.1158/0008-5472.Can-15-1456  0.463
2016 Munn DH, Mellor AL. IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance. Trends in Immunology. 37: 193-207. PMID 26839260 DOI: 10.1016/J.It.2016.01.002  0.459
2015 Sharma MD, Shinde R, McGaha TL, Huang L, Holmgaard RB, Wolchok JD, Mautino MR, Celis E, Sharpe AH, Francisco LM, Powell JD, Yagita H, Mellor AL, Blazar BR, Munn DH. The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment. Science Advances. 1: e1500845. PMID 26601142 DOI: 10.1126/Sciadv.1500845  0.405
2015 Chaudhary K, Shinde R, Liu H, Gnana-Prakasam JP, Veeranan-Karmegam R, Huang L, Ravishankar B, Bradley J, Kvirkvelia N, McMenamin M, Xiao W, Kleven D, Mellor AL, Madaio MP, McGaha TL. Amino Acid Metabolism Inhibits Antibody-Driven Kidney Injury by Inducing Autophagy. Journal of Immunology (Baltimore, Md. : 1950). 194: 5713-24. PMID 25980011 DOI: 10.4049/Jimmunol.1500277  0.321
2015 Suryawanshi A, Manoharan I, Hong Y, Swafford D, Majumdar T, Taketo MM, Manicassamy B, Koni PA, Thangaraju M, Sun Z, Mellor AL, Munn DH, Manicassamy S. Canonical wnt signaling in dendritic cells regulates Th1/Th17 responses and suppresses autoimmune neuroinflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 3295-304. PMID 25710911 DOI: 10.4049/Jimmunol.1402691  0.429
2015 Paschall AV, Zhang R, Qi CF, Bardhan K, Peng L, Lu G, Yang J, Merad M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse HC, Ozato K, Xiong H, et al. IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation. Journal of Immunology (Baltimore, Md. : 1950). 194: 2369-79. PMID 25646302 DOI: 10.4049/Jimmunol.1402412  0.507
2015 Hong Y, Manoharan I, Suryawanshi A, Majumdar T, Angus-Hill ML, Koni PA, Manicassamy B, Mellor AL, Munn DH, Manicassamy S. β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells. Cancer Research. 75: 656-65. PMID 25568183 DOI: 10.1158/0008-5472.Can-14-2377  0.47
2015 Lu X, Ding ZC, Cao Y, Liu C, Habtetsion T, Yu M, Lemos H, Salman H, Xu H, Mellor AL, Zhou G. Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 2011-21. PMID 25560408 DOI: 10.4049/Jimmunol.1401894  0.507
2015 Sharma M, Shinde R, McGaha T, Huang L, Holmgaard R, Wolchok J, Mautino M, Celis E, Sharpe A, Francisco L, Powell J, Yagita H, Mellor A, Blazar B, Munn D. The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells Journal For Immunotherapy of Cancer. 3: O19. DOI: 10.1186/2051-1426-3-S2-O19  0.48
2015 Paschall A, Zhang R, Bardhan K, Qi C, Peng L, Lu G, Yang J, Merad M, Zimmerman M, McGaha T, Zhou G, Mellor A, Abrams SI, Morse H, Ozato K, et al. Abstract PR05: IRF8 regulates GM-CSF expression in T cells and tumor cells to mediate myeloid-derived suppressor cell differentiation Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-Pr05  0.493
2014 Manoharan I, Hong Y, Suryawanshi A, Angus-Hill ML, Sun Z, Mellor AL, Munn DH, Manicassamy S. TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation. Journal of Immunology (Baltimore, Md. : 1950). 193: 4203-13. PMID 25210120 DOI: 10.4049/Jimmunol.1400614  0.465
2014 Lemos H, Huang L, McGaha TL, Mellor AL. Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA. European Journal of Immunology. 44: 2847-53. PMID 25143264 DOI: 10.1002/Eji.201344407  0.401
2014 Li M, Bolduc AR, Hoda MN, Gamble DN, Dolisca SB, Bolduc AK, Hoang K, Ashley C, McCall D, Rojiani AM, Maria BL, Rixe O, MacDonald TJ, Heeger PS, Mellor AL, et al. The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma. Journal For Immunotherapy of Cancer. 2: 21. PMID 25054064 DOI: 10.1186/2051-1426-2-21  0.417
2014 Bozec A, Zaiss MM, Kagwiria R, Voll R, Rauh M, Chen Z, Mueller-Schmucker S, Kroczek RA, Heinzerling L, Moser M, Mellor AL, David JP, Schett G. T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway. Science Translational Medicine. 6: 235ra60. PMID 24807557 DOI: 10.1126/Scitranslmed.3007764  0.436
2014 Lemos H, Huang L, Chandler PR, Mohamed E, Souza GR, Li L, Pacholczyk G, Barber GN, Hayakawa Y, Munn DH, Mellor AL. Activation of the STING adaptor attenuates experimental autoimmune encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 192: 5571-8. PMID 24799564 DOI: 10.4049/Jimmunol.1303258  0.464
2014 Ding ZC, Lu X, Yu M, Lemos H, Huang L, Chandler P, Liu K, Walters M, Krasinski A, Mack M, Blazar BR, Mellor AL, Munn DH, Zhou G. Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T-cell responses through the PD-1-PD-L1 axis. Cancer Research. 74: 3441-53. PMID 24780756 DOI: 10.1158/0008-5472.Can-13-3596  0.474
2014 Sage LK, Fox JM, Mellor AL, Tompkins SM, Tripp RA. Indoleamine 2,3-dioxygenase (IDO) activity during the primary immune response to influenza infection modifies the memory T cell response to influenza challenge. Viral Immunology. 27: 112-23. PMID 24702331 DOI: 10.1089/Vim.2013.0105  0.378
2014 Ravishankar B, Shinde R, Liu H, Chaudhary K, Bradley J, Lemos HP, Chandler P, Tanaka M, Munn DH, Mellor AL, McGaha TL. Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance. Proceedings of the National Academy of Sciences of the United States of America. 111: 4215-20. PMID 24591636 DOI: 10.1073/Pnas.1320924111  0.517
2014 Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LM, Pigott E, Keough MP, Rust S, Mellor AL, Mandik-Nayak L, Muller AJ, Prendergast GC. IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation. International Immunology. 26: 357-67. PMID 24402311 DOI: 10.1093/Intimm/Dxt073  0.441
2014 Huang L, Mellor AL. Metabolic control of tumour progression and antitumour immunity. Current Opinion in Oncology. 26: 92-9. PMID 24305570 DOI: 10.1097/Cco.0000000000000035  0.354
2014 Liu H, Huang L, Bradley J, Liu K, Bardhan K, Ron D, Mellor AL, Munn DH, McGaha TL. GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology. Molecular and Cellular Biology. 34: 428-38. PMID 24248597 DOI: 10.1128/Mcb.00946-13  0.346
2013 Huang L, Li L, Lemos H, Chandler PR, Pacholczyk G, Baban B, Barber GN, Hayakawa Y, McGaha TL, Ravishankar B, Munn DH, Mellor AL. Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses. Journal of Immunology (Baltimore, Md. : 1950). 191: 3509-13. PMID 23986532 DOI: 10.4049/Jimmunol.1301419  0.477
2013 Jrad-Lamine A, Henry-Berger J, Damon-Soubeyrand C, Saez F, Kocer A, Janny L, Pons-Rejraji H, Munn DH, Mellor AL, Gharbi N, Cadet R, Guiton R, Aitken RJ, Drevet JR. Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment. Plos One. 8: e66494. PMID 23840489 DOI: 10.1371/Journal.Pone.0066494  0.365
2013 Huang L, Li L, Klonowski KD, Tompkins SM, Tripp RA, Mellor AL. Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection. Plos One. 8: e66546. PMID 23785507 DOI: 10.1371/Journal.Pone.0066546  0.433
2013 Sharma MD, Huang L, Choi JH, Lee EJ, Wilson JM, Lemos H, Pan F, Blazar BR, Pardoll DM, Mellor AL, Shi H, Munn DH. An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity. 38: 998-1012. PMID 23684987 DOI: 10.1016/J.Immuni.2013.01.013  0.483
2013 Xiao H, Peng Y, Hong Y, Huang L, Guo ZS, Bartlett DL, Fu N, Munn DH, Mellor A, He Y. Local administration of TLR ligands rescues the function of tumor-infiltrating CD8 T cells and enhances the antitumor effect of lentivector immunization. Journal of Immunology (Baltimore, Md. : 1950). 190: 5866-73. PMID 23610140 DOI: 10.4049/Jimmunol.1203470  0.455
2013 Fox JM, Sage LK, Huang L, Barber J, Klonowski KD, Mellor AL, Tompkins SM, Tripp RA. Inhibition of indoleamine 2,3-dioxygenase enhances the T-cell response to influenza virus infection. The Journal of General Virology. 94: 1451-61. PMID 23580425 DOI: 10.1099/Vir.0.053124-0  0.401
2013 Riella LV, Dada S, Chabtini L, Smith B, Huang L, Dakle P, Mfarrej B, D'Addio F, Adams LT, Kochupurakkal N, Vergani A, Fiorina P, Mellor AL, Sharpe AH, Yagita H, et al. B7h (ICOS-L) maintains tolerance at the fetomaternal interface. The American Journal of Pathology. 182: 2204-13. PMID 23578385 DOI: 10.1016/J.Ajpath.2013.02.014  0.511
2013 Koni PA, Bolduc A, Takezaki M, Ametani Y, Huang L, Lee JR, Nutt SL, Kamanaka M, Flavell RA, Mellor AL, Tsubata T, Shimoda M. Constitutively CD40-activated B cells regulate CD8 T cell inflammatory response by IL-10 induction. Journal of Immunology (Baltimore, Md. : 1950). 190: 3189-96. PMID 23440421 DOI: 10.4049/Jimmunol.1203364  0.521
2013 Munn DH, Mellor AL. Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends in Immunology. 34: 137-43. PMID 23103127 DOI: 10.1016/J.It.2012.10.001  0.401
2012 McGaha TL, Huang L, Lemos H, Metz R, Mautino M, Prendergast GC, Mellor AL. Amino acid catabolism: a pivotal regulator of innate and adaptive immunity. Immunological Reviews. 249: 135-57. PMID 22889220 DOI: 10.1111/J.1600-065X.2012.01149.X  0.371
2012 Ding ZC, Huang L, Blazar BR, Yagita H, Mellor AL, Munn DH, Zhou G. Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy. Blood. 120: 2229-39. PMID 22859605 DOI: 10.1182/Blood-2011-12-398321  0.508
2012 Li L, Huang L, Lemos HP, Mautino M, Mellor AL. Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases. Frontiers in Immunology. 3: 109. PMID 22593757 DOI: 10.3389/Fimmu.2012.00109  0.339
2012 Huang L, Lemos HP, Li L, Li M, Chandler PR, Baban B, McGaha TL, Ravishankar B, Lee JR, Munn DH, Mellor AL. Engineering DNA nanoparticles as immunomodulatory reagents that activate regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 4913-20. PMID 22516958 DOI: 10.4049/Jimmunol.1103668  0.469
2012 Ravishankar B, Liu H, Shinde R, Chandler P, Baban B, Tanaka M, Munn DH, Mellor AL, Karlsson MC, McGaha TL. Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase. Proceedings of the National Academy of Sciences of the United States of America. 109: 3909-14. PMID 22355111 DOI: 10.1073/Pnas.1117736109  0.507
2012 Divanovic S, Sawtell NM, Trompette A, Warning JI, Dias A, Cooper AM, Yap GS, Arditi M, Shimada K, Duhadaway JB, Prendergast GC, Basaraba RJ, Mellor AL, Munn DH, Aliberti J, et al. Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection. The Journal of Infectious Diseases. 205: 152-61. PMID 21990421 DOI: 10.1093/Infdis/Jir621  0.351
2012 Miller BJ, Gassama B, Sebastian D, Buckley P, Mellor A. 80. Meta-analysis of monocytes and lymphocytes in schizophrenia: Clinical status and antipsychotic effects Brain Behavior and Immunity. 26. DOI: 10.1016/J.Bbi.2012.07.104  0.397
2011 Medzhitov R, Shevach EM, Trinchieri G, Mellor AL, Munn DH, Gordon S, Libby P, Hansson GK, Shortman K, Dong C, Gabrilovich D, GabryÅ¡ová L, Howes A, O'Garra A. Highlights of 10 years of immunology in Nature Reviews Immunology. Nature Reviews. Immunology. 11: 693-702. PMID 21941295 DOI: 10.1038/Nri3063  0.407
2011 Baban B, Chandler PR, Johnson BA, Huang L, Li M, Sharpe ML, Francisco LM, Sharpe AH, Blazar BR, Munn DH, Mellor AL. Physiologic control of IDO competence in splenic dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 2329-35. PMID 21813777 DOI: 10.4049/Jimmunol.1100276  0.559
2011 Mellor AL, Munn DH. Physiologic control of the functional status of Foxp3+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 4535-40. PMID 21464094 DOI: 10.4049/Jimmunol.1002937  0.534
2011 Diana J, Brezar V, Beaudoin L, Dalod M, Mellor AL, Tafuri A, Herrath Mv, Boitard C, Mallone R, Lehuen A. Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay. Journal of Experimental Medicine. 208: 729-745. PMID 21444661 DOI: 10.1084/Jem.20101692  0.48
2011 Makala LH, Baban B, Lemos H, El-Awady AR, Chandler PR, Hou DY, Munn DH, Mellor AL. Leishmania major attenuates host immunity by stimulating local indoleamine 2,3-dioxygenase expression. The Journal of Infectious Diseases. 203: 715-25. PMID 21282196 DOI: 10.1093/Infdis/Jiq095  0.491
2011 Jrad-Lamine A, Henry-Berger J, Gourbeyre P, Damon-Soubeyrand C, Lenoir A, Combaret L, Saez F, Kocer A, Tone S, Fuchs D, Zhu W, Oefner PJ, Munn DH, Mellor AL, Gharbi N, et al. Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state. The Journal of Biological Chemistry. 286: 8030-42. PMID 21189261 DOI: 10.1074/Jbc.M110.172114  0.36
2010 Sharma MD, Hou DY, Baban B, Koni PA, He Y, Chandler PR, Blazar BR, Mellor AL, Munn DH. Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice. Immunity. 33: 942-54. PMID 21145762 DOI: 10.1016/J.Immuni.2010.11.022  0.561
2010 Zhou Q, Xiao H, Liu Y, Peng Y, Hong Y, Yagita H, Chandler P, Munn DH, Mellor A, Fu N, He Y. Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization. Journal of Immunology (Baltimore, Md. : 1950). 185: 5082-92. PMID 20926790 DOI: 10.4049/Jimmunol.1001821  0.447
2010 Johnson BA, Kahler DJ, Baban B, Chandler PR, Kang B, Shimoda M, Koni PA, Pihkala J, Vilagos B, Busslinger M, Munn DH, Mellor AL. B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proceedings of the National Academy of Sciences of the United States of America. 107: 10644-8. PMID 20498068 DOI: 10.1073/Pnas.0914347107  0.558
2010 Huang L, Baban B, Johnson BA, Mellor AL. Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege. International Reviews of Immunology. 29: 133-55. PMID 20367139 DOI: 10.3109/08830180903349669  0.547
2010 Ding ZC, Blazar BR, Mellor AL, Munn DH, Zhou G. Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood. 115: 2397-406. PMID 20118405 DOI: 10.1182/Blood-2009-11-253336  0.534
2010 Singh N, Yamamoto M, Takami M, Seki Y, Takezaki M, Mellor AL, Iwashima M. CD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 184: 94-104. PMID 19949106 DOI: 10.4049/Jimmunol.0900753  0.502
2010 Lanz TV, Opitz CA, Ho PP, Agrawal A, Lutz C, Weller M, Mellor AL, Steinman L, Wick W, Platten M. Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1). Stem Cells and Development. 19: 657-68. PMID 19886804 DOI: 10.1089/Scd.2009.0385  0.504
2009 Johnson BA, Baban B, Mellor AL. Targeting the immunoregulatory indoleamine 2,3 dioxygenase pathway in immunotherapy. Immunotherapy. 1: 645-61. PMID 20161103 DOI: 10.2217/Imt.09.21  0.509
2009 Jasperson LK, Bucher C, Panoskaltsis-Mortari A, Mellor AL, Munn DH, Blazar BR. Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality. Blood. 114: 5062-70. PMID 19828695 DOI: 10.1182/Blood-2009-06-227587  0.494
2009 Baban B, Chandler PR, Sharma MD, Pihkala J, Koni PA, Munn DH, Mellor AL. IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 2475-83. PMID 19635913 DOI: 10.4049/Jimmunol.0900986  0.523
2009 Cobbold SP, Adams E, Farquhar CA, Nolan KF, Howie D, Lui KO, Fairchild PJ, Mellor AL, Ron D, Waldmann H. Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 12055-60. PMID 19567830 DOI: 10.1073/Pnas.0903919106  0.523
2009 Coquerelle C, Oldenhove G, Acolty V, Denoeud J, Vansanten G, Verdebout JM, Mellor A, Bluestone JA, Moser M. Anti-CTLA-4 treatment induces IL-10-producing ICOS+ regulatory T cells displaying IDO-dependent anti-inflammatory properties in a mouse model of colitis. Gut. 58: 1363-73. PMID 19505881 DOI: 10.1136/Gut.2008.162842  0.456
2009 Sharma MD, Hou DY, Liu Y, Koni PA, Metz R, Chandler P, Mellor AL, He Y, Munn DH. Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes. Blood. 113: 6102-11. PMID 19366986 DOI: 10.1182/Blood-2008-12-195354  0.508
2009 Kim YH, Choi BK, Kang WJ, Kim KH, Kang SW, Mellor AL, Munn DH, Kwon BS. IFN-gamma-indoleamine-2,3 dioxygenase acts as a major suppressive factor in 4-1BB-mediated immune suppression in vivo. Journal of Leukocyte Biology. 85: 817-25. PMID 19218483 DOI: 10.1189/Jlb.0408246  0.529
2009 Colvin BL, Sumpter TL, Tokita D, Salati J, Mellor AL, Thomson AW. Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression. Human Immunology. 70: 313-20. PMID 19208362 DOI: 10.1016/J.Humimm.2009.01.021  0.517
2009 Kahler DJ, Mellor AL. T cell regulatory plasmacytoid dendritic cells expressing indoleamine 2,3 dioxygenase. Handbook of Experimental Pharmacology. 165-96. PMID 19031026 DOI: 10.1007/978-3-540-71029-5_8  0.539
2008 Muller AJ, Sharma MD, Chandler PR, Duhadaway JB, Everhart ME, Johnson BA, Kahler DJ, Pihkala J, Soler AP, Munn DH, Prendergast GC, Mellor AL. Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase. Proceedings of the National Academy of Sciences of the United States of America. 105: 17073-8. PMID 18952840 DOI: 10.1073/Pnas.0806173105  0.485
2008 Xu H, Oriss TB, Fei M, Henry AC, Melgert BN, Chen L, Mellor AL, Munn DH, Irvin CG, Ray P, Ray A. Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation. Proceedings of the National Academy of Sciences of the United States of America. 105: 6690-5. PMID 18436652 DOI: 10.1073/Pnas.0708809105  0.404
2008 Harrington L, Srikanth CV, Antony R, Rhee SJ, Mellor AL, Shi HN, Cherayil BJ. Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis. Infection and Immunity. 76: 3045-53. PMID 18426872 DOI: 10.1128/Iai.00193-08  0.358
2008 Jasperson LK, Bucher C, Panoskaltsis-Mortari A, Taylor PA, Mellor AL, Munn DH, Blazar BR. Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality. Blood. 111: 3257-65. PMID 18077788 DOI: 10.1182/Blood-2007-06-096081  0.504
2008 Mellor AL, Munn DH. Creating immune privilege: active local suppression that benefits friends, but protects foes. Nature Reviews. Immunology. 8: 74-80. PMID 18064049 DOI: 10.1038/Nri2233  0.374
2008 Banerjee T, Duhadaway JB, Gaspari P, Sutanto-Ward E, Munn DH, Mellor AL, Malachowski WP, Prendergast GC, Muller AJ. A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase. Oncogene. 27: 2851-7. PMID 18026137 DOI: 10.1038/Sj.Onc.1210939  0.39
2008 Mellor AL, Munn DH. Creating immune privilege: Active local suppression that benefits friends, but protects foes (Nature Reviews Immunology (2008) 8, (24-80)) Nature Reviews Immunology. 8. DOI: 10.1038/Nri2264  0.33
2007 Sharma MD, Baban B, Chandler P, Hou DY, Singh N, Yagita H, Azuma M, Blazar BR, Mellor AL, Munn DH. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. The Journal of Clinical Investigation. 117: 2570-82. PMID 17710230 DOI: 10.1172/Jci31911  0.401
2007 Munn DH, Mellor AL. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. The Journal of Clinical Investigation. 117: 1147-54. PMID 17476344 DOI: 10.1172/Jci31178  0.389
2007 Singh N, Chandler PR, Seki Y, Baban B, Takezaki M, Kahler DJ, Munn DH, Larsen CP, Mellor AL, Iwashima M. Role of CD28 in fatal autoimmune disorder in scurfy mice. Blood. 110: 1199-206. PMID 17463170 DOI: 10.1182/Blood-2006-10-054585  0.519
2007 Manlapat AK, Kahler DJ, Chandler PR, Munn DH, Mellor AL. Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19+ dendritic cells. European Journal of Immunology. 37: 1064-71. PMID 17343295 DOI: 10.1002/Eji.200636690  0.761
2007 Hou DY, Muller AJ, Sharma MD, DuHadaway J, Banerjee T, Johnson M, Mellor AL, Prendergast GC, Munn DH. Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses. Cancer Research. 67: 792-801. PMID 17234791 DOI: 10.1158/0008-5472.Can-06-2925  0.416
2007 Keskin DB, Marshall B, Munn D, Mellor AL, Gearhart DA. Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase. Cellular & Molecular Biology Letters. 12: 82-102. PMID 17103092 DOI: 10.2478/S11658-006-0048-9  0.603
2007 Jasperson LK, Panoskaltsis-Mortari A, Taylor PA, Bucher C, Mellor AL, Munn DH, Blazar BR. Host Indoleamine 2,3-Dioxygenase Is a Critical Regulator of Acute GVHD Lethality. Blood. 110: 352-352. DOI: 10.1182/Blood.V110.11.352.352  0.519
2006 Seymour RL, Ganapathy V, Mellor AL, Munn DH. A high-affinity, tryptophan-selective amino acid transport system in human macrophages. Journal of Leukocyte Biology. 80: 1320-7. PMID 16997853 DOI: 10.1189/Jlb.1205727  0.35
2006 Munn DH, Mellor AL. The tumor-draining lymph node as an immune-privileged site. Immunological Reviews. 213: 146-58. PMID 16972902 DOI: 10.1111/J.1600-065X.2006.00444.X  0.404
2006 Singh N, Seki Y, Takami M, Baban B, Chandler PR, Khosravi D, Zheng X, Takezaki M, Lee JR, Mellor AL, Bollag WB, Iwashima M. Enrichment of regulatory CD4(+)CD25(+) T cells by inhibition of phospholipase D signaling. Nature Methods. 3: 629-36. PMID 16862138 DOI: 10.1038/Nmeth903  0.524
2006 Mellor AL, Munn DH. Immune privilege: a recurrent theme in immunoregulation? Immunological Reviews. 213: 5-11. DOI: 10.1111/J.1600-065X.2006.00443.X  0.374
2005 Mellor AL, Baban B, Chandler PR, Manlapat A, Kahler DJ, Munn DH. Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 5601-5. PMID 16237046 DOI: 10.4049/Jimmunol.175.9.5601  0.792
2005 Mellor A. Indoleamine 2,3 dioxygenase and regulation of T cell immunity. Biochemical and Biophysical Research Communications. 338: 20-4. PMID 16157293 DOI: 10.1016/J.Bbrc.2005.08.232  0.516
2005 Guleria I, Khosroshahi A, Ansari MJ, Habicht A, Azuma M, Yagita H, Noelle RJ, Coyle A, Mellor AL, Khoury SJ, Sayegh MH. A critical role for the programmed death ligand 1 in fetomaternal tolerance. The Journal of Experimental Medicine. 202: 231-7. PMID 16027236 DOI: 10.1084/Jem.20050019  0.458
2005 Baban B, Hansen AM, Chandler PR, Manlapat A, Bingaman A, Kahler DJ, Munn DH, Mellor AL. A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation. International Immunology. 17: 909-19. PMID 15967784 DOI: 10.1093/Intimm/Dxh271  0.777
2005 Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, Mellor AL. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity. 22: 633-42. PMID 15894280 DOI: 10.1016/J.Immuni.2005.03.013  0.527
2005 Munn DH, Mellor AL, Rossi M, Young JW. Dendritic cells have the option to express IDO-mediated suppression or not. Blood. 105: 2618. PMID 15746089 DOI: 10.1182/Blood-2005-01-0122  0.351
2004 Mellor AL, Munn D. Policing pregnancy: Tregs help keep the peace. Trends in Immunology. 25: 563-5. PMID 15489182 DOI: 10.1016/J.It.2004.09.001  0.492
2004 Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nature Reviews. Immunology. 4: 762-74. PMID 15459668 DOI: 10.1038/Nri1457  0.447
2004 Mellor AL, Chandler P, Baban B, Hansen AM, Marshall B, Pihkala J, Waldmann H, Cobbold S, Adams E, Munn DH. Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase. International Immunology. 16: 1391-401. PMID 15351783 DOI: 10.1093/Intimm/Dxh140  0.553
2004 Munn DH, Sharma MD, Hou D, Baban B, Lee JR, Antonia SJ, Messina JL, Chandler P, Koni PA, Mellor AL. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. The Journal of Clinical Investigation. 114: 280-90. PMID 15254595 DOI: 10.1172/Jci21583  0.547
2004 Baban B, Chandler P, McCool D, Marshall B, Munn DH, Mellor AL. Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific. Journal of Reproductive Immunology. 61: 67-77. PMID 15063630 DOI: 10.1016/J.Jri.2003.11.003  0.337
2004 Munn DH, Sharma MD, Mellor AL. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 4100-10. PMID 15034022 DOI: 10.4049/Jimmunol.172.7.4100  0.562
2004 Munn DH, Mellor AL. IDO and tolerance to tumors. Trends in Molecular Medicine. 10: 15-8. PMID 14720581 DOI: 10.1016/J.Molmed.2003.11.003  0.339
2004 Munn DH, Sharma MD, Hou D, Baban B, Lee JR, Antonia SJ, Messina JL, Chandler P, Koni PA, Mellor AL. Erratum: Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes (Journal of Clinical Investigation (2004) 114 (280-290) DOI:10.1172/JCI200421583) Journal of Clinical Investigation. 114. DOI: 10.1172/Jci200421583E1  0.319
2003 Mellor AL, Munn D, Chandler P, Keskin D, Johnson T, Marshall B, Jhaver K, Baban B. Tryptophan catabolism and T cell responses. Advances in Experimental Medicine and Biology. 527: 27-35. PMID 15206713 DOI: 10.1007/978-1-4615-0135-0_3  0.705
2003 Lee JR, Dalton RR, Messina JL, Sharma MD, Smith DM, Burgess RE, Mazzella F, Antonia SJ, Mellor AL, Munn DH. Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 1457-66. PMID 14563947 DOI: 10.1097/01.Lab.0000090158.68852.D1  0.362
2003 Mellor AL, Baban B, Chandler P, Marshall B, Jhaver K, Hansen A, Koni PA, Iwashima M, Munn DH. Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. Journal of Immunology (Baltimore, Md. : 1950). 171: 1652-5. PMID 12902462 DOI: 10.4049/Jimmunol.171.4.1652  0.544
2003 Mellor AL, Munn DH. Tryptophan catabolism and regulation of adaptive immunity. Journal of Immunology (Baltimore, Md. : 1950). 170: 5809-13. PMID 12794104 DOI: 10.4049/Jimmunol.170.12.5809  0.346
2003 Munn DH, Mellor AL. Macrophages and the regulation of self-reactive T cells. Current Pharmaceutical Design. 9: 257-64. PMID 12570830 DOI: 10.2174/1381612033392026  0.438
2002 Lee GK, Park HJ, Macleod M, Chandler P, Munn DH, Mellor AL. Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division. Immunology. 107: 452-60. PMID 12460190 DOI: 10.1046/J.1365-2567.2002.01526.X  0.53
2002 Mellor AL, Chandler P, Lee GK, Johnson T, Keskin DB, Lee J, Munn DH. Indoleamine 2,3-dioxygenase, immunosuppression and pregnancy. Journal of Reproductive Immunology. 57: 143-50. PMID 12385839 DOI: 10.1016/S0165-0378(02)00040-2  0.637
2002 Munn DH, Sharma MD, Lee JR, Jhaver KG, Johnson TS, Keskin DB, Marshall B, Chandler P, Antonia SJ, Burgess R, Slingluff CL, Mellor AL. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science (New York, N.Y.). 297: 1867-70. PMID 12228717 DOI: 10.1126/Science.1073514  0.734
2002 Friberg M, Jennings R, Alsarraj M, Dessureault S, Cantor A, Extermann M, Mellor AL, Munn DH, Antonia SJ. Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection. International Journal of Cancer. Journal International Du Cancer. 101: 151-5. PMID 12209992 DOI: 10.1002/Ijc.10645  0.416
2002 Mellor AL, Keskin DB, Johnson T, Chandler P, Munn DH. Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 168: 3771-6. PMID 11937528 DOI: 10.4049/Jimmunol.168.8.3771  0.717
2002 Fallarino F, Vacca C, Orabona C, Belladonna ML, Bianchi R, Marshall B, Keskin DB, Mellor AL, Fioretti MC, Grohmann U, Puccetti P. Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. International Immunology. 14: 65-8. PMID 11751753 DOI: 10.1093/Intimm/14.1.65  0.742
2002 Mellor AL, Munn DH. Tryptophan catabolism prevents maternal T cells from activating lethal anti-fetal immune responses. Journal of Reproductive Immunology. 52: 5-13. PMID 11600174 DOI: 10.1016/S0165-0378(01)00118-8  0.436
2001 Mellor AL, Munn DH. Extinguishing maternal immune responses during pregnancy: implications for immunosuppression. Seminars in Immunology. 13: 213-8. PMID 11437628 DOI: 10.1006/Smim.2000.0317  0.471
2001 Marshall B, Keskin DB, Mellor AL. Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme. Bmc Biochemistry. 2: 5. PMID 11375052 DOI: 10.1186/1471-2091-2-5  0.629
2001 Horuzsko A, Lenfant F, Munn DH, Mellor AL. Maturation of antigen-presenting cells is compromised in HLA-G transgenic mice. International Immunology. 13: 385-94. PMID 11222508 DOI: 10.1093/Intimm/13.3.385  0.448
2001 Mellor AL, Sivakumar J, Chandler P, Smith K, Molina H, Mao D, Munn DH. Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy. Nature Immunology. 2: 64-8. PMID 11135580 DOI: 10.1038/83183  0.495
2000 Mellor AL, Munn DH. Immunology at the maternal-fetal interface: lessons for T cell tolerance and suppression. Annual Review of Immunology. 18: 367-91. PMID 10837063 DOI: 10.1146/ANNUREV.IMMUNOL.18.1.367  0.345
1999 Mellor AL, Munn DH. Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation? Immunology Today. 20: 469-73. PMID 10500295 DOI: 10.1016/S0167-5699(99)01520-0  0.475
1999 Mellor A, Zhou M, Conway SJ, Munn D. HLA-G transgenic mice. Journal of Reproductive Immunology. 43: 253-61. PMID 10479061 DOI: 10.1016/S0165-0378(99)00027-3  0.415
1999 Horuzsko A, Portik-Dobos V, Hansen KA, Markowitz RB, Helman SW, Mellor AL. Induction of HLA-G-specific human CD8+ T cell lines by stimulation across a polymorphism of HLA-G. Transplantation Proceedings. 31: 1860-3. PMID 10371974 DOI: 10.1016/S0041-1345(99)00189-X  0.405
1999 Munn DH, Shafizadeh E, Attwood JT, Bondarev I, Pashine A, Mellor AL. Inhibition of T cell proliferation by macrophage tryptophan catabolism. The Journal of Experimental Medicine. 189: 1363-72. PMID 10224276 DOI: 10.1084/Jem.189.9.1363  0.545
1999 Zhou M, Mellor AL. Expanded cohorts of maternal CD8+ T-cells specific for paternal MHC class I accumulate during pregnancy. Journal of Reproductive Immunology. 40: 47-62. PMID 9862256 DOI: 10.1016/S0165-0378(98)00030-8  0.494
1999 Jones ND, Fluck NC, Mellor AL, Morris PJ, Wood KJ. The induction of transplantation tolerance by intrathymic (i.t.) delivery of alloantigen: a critical relationship between i.t. deletion, thymic export of new T cells and the timing of transplantation. International Immunology. 10: 1637-46. PMID 9846692 DOI: 10.1093/Intimm/10.11.1637  0.416
1998 Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, Brown C, Mellor AL. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science (New York, N.Y.). 281: 1191-3. PMID 9712583 DOI: 10.1126/Science.281.5380.1191  0.444
1998 Fragoso G, Lamoyi E, Mellor A, Lomelí C, Hernández M, Sciutto E. Increased resistance to Taenia crassiceps murine cysticercosis in Qa-2 transgenic mice Infection and Immunity. 66: 760-764. PMID 9453638 DOI: 10.1128/Iai.66.2.760-764.1998  0.327
1997 Scully R, Cobbold SP, Mellor AL, Wissing M, Arnold B, Waldmann H. A role for Th2 cytokines in the suppression of CD8+ T cell-mediated graft rejection. European Journal of Immunology. 27: 1663-70. PMID 9247575 DOI: 10.1002/EJI.1830270711  0.371
1997 Jones ND, Fluck NC, Roelen DL, Mellor AL, Morris PJ, Wood KJ. Deletion of alloantigen-reactive thymocytes as a mechanism of adult tolerance induction following intrathymic antigen administration. European Journal of Immunology. 27: 1591-600. PMID 9247566 DOI: 10.1002/Eji.1830270702  0.506
1997 Horuzsko A, Antoniou J, Tomlinson P, Portik-Dobos V, Mellor AL. HLA-G functions as a restriction element and a transplantation antigen in mice. International Immunology. 9: 645-53. PMID 9184910 DOI: 10.1093/Intimm/9.5.645  0.365
1997 Zelenika D, Cobbold SP, Mellor AL, Simpson E, Waldman H. Study of mechanisms of peripheral tolerance by T cell receptor transgenic mice Immunology Letters. 56: 249. DOI: 10.1016/S0165-2478(97)85991-3  0.404
1997 Simpson SJ, Mellor A, Terhorst C, Tonegawa S, Levelt C. CD8α+β− intestinal intraepithelial lymphocytes in T cell receptor transgenic mice are positively selected by high affinity ligands Immunology Letters. 56: 99. DOI: 10.1016/S0165-2478(97)85392-8  0.378
1997 Mellor AL, Zhou M. Maternal T cells respond abortively to paternally inherited MHC class I expressed on trophoblast Journal of Reproductive Immunology. 34: 74. DOI: 10.1016/S0165-0378(97)90449-6  0.419
1997 Horuzsko A, Portik-Dobos V, Mellor A. HLA-G present peptides to murine CD8 T cells in transgenic mice Journal of Reproductive Immunology. 34: 73. DOI: 10.1016/S0165-0378(97)90448-4  0.439
1996 Douek DC, Corley KTT, Zal T, Mellor A, Julian Dyson P, Altmann DM. Negative selection by endogenous antigen and superantigen occurs at multiple thymic sites International Immunology. 8: 1413-1420. PMID 8921419 DOI: 10.1093/Intimm/8.9.1413  0.302
1996 Schulz R, Mellor AL. Self major histocompatibility complex class I antigens expressed solely in lymphoid cells do not induce tolerance in the CD4+ T cell compartment. The Journal of Experimental Medicine. 184: 1573-8. PMID 8879232 DOI: 10.1084/JEM.184.4.1573  0.419
1996 Zal T, Weiss S, Mellor A, Stockinger B. Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function. Proceedings of the National Academy of Sciences of the United States of America. 93: 9102-7. PMID 8799161 DOI: 10.1073/Pnas.93.17.9102  0.439
1996 Tarazona R, Sponaas AM, Mavria G, Zhou M, Schulz R, Tomlinson P, Antoniou J, Mellor AL. Effects of different antigenic microenvironments on the course of CD8+ T cell responses in vivo. International Immunology. 8: 351-8. PMID 8671621 DOI: 10.1093/Intimm/8.3.351  0.531
1995 Sponaas AM, Tomlinson PD, Schulz R, Antoniou J, Ize-Iyamu P, Schmitt-Verhulst AM, Mellor AL. Tolerance induction by elimination of subsets of self-reactive thymocytes. International Immunology. 6: 1593-604. PMID 7826949 DOI: 10.1093/Intimm/6.10.1593  0.462
1994 Ferber I, Schönrich G, Schenkel J, Mellor AL, Hämmerling GJ, Arnold B. Levels of peripheral T cell tolerance induced by different doses of tolerogen. Science (New York, N.Y.). 263: 674-6. PMID 8303275 DOI: 10.1126/Science.8303275  0.515
1994 Auphan N, Curnow J, Guimezanes A, Langlet C, Malissen B, Mellor A, Schmitt-Verhulst AM. The degree of CD8 dependence of cytolytic T cell precursors is determined by the nature of the T cell receptor (TCR) and influences negative selection in TCR-transgenic mice. European Journal of Immunology. 24: 1572-7. PMID 8026519 DOI: 10.1002/eji.1830240718  0.392
1994 Sponaas AM, Tomlinson PD, Antoniou J, Auphan N, Langlet C, Malissen B, Schmitt-Verhulst AM, Mellor AL. Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters. International Immunology. 6: 277-87. PMID 7512374 DOI: 10.1093/Intimm/6.2.277  0.449
1993 Simpson SJ, Tomlinson P, Mellor AL. Immunological consequences of T cell-specific expression of H-2Kb molecules in transgenic mice International Immunology. 5: 189-198. PMID 8095799 DOI: 10.1093/Intimm/5.2.189  0.436
1992 Yeoman H, Mellor AL. Tolerance and MHC restriction in transgenic mice expressing a MHC class I gene in erythroid cells. International Immunology. 4: 59-65. PMID 1540549 DOI: 10.1093/Intimm/4.1.59  0.423
1992 Husbands SD, Schönrich G, Arnold B, Chandler PR, Simpson E, Philpott KL, Tomlinson P, O'Reilly L, Cooke A, Mellor AL. Expression of major histocompatibility complex class I antigens at low levels in the thymus induces T cell tolerance via a non-deletional mechanism. European Journal of Immunology. 22: 2655-61. PMID 1396970 DOI: 10.1002/Eji.1830221027  0.432
1991 Mellor AL, Tomlinson PD, Antoniou J, Chandler P, Robinson P, Felstein M, Sloan J, Edwards A, O'Reilly L, Cooke A. Expression and function of Qa-2 major histocompatibility complex class I molecules in transgenic mice. International Immunology. 3: 493-502. PMID 1911536 DOI: 10.1093/Intimm/3.5.493  0.368
1989 Robinson PJ, Millrain M, Antoniou J, Simpson E, Mellor AL. A glycophospholipid anchor is required for Qa-2-mediated T cell activation. Nature. 342: 85-7. PMID 2530453 DOI: 10.1038/342085A0  0.437
1986 Fernandez N, Festenstein H, Alonzo A, Biro PA, Labeta M, Carolan E, Houlihan J, Mellor A, Flavell R. THE EXPRESSION OF MURINE Qa REGION GENE PRODUCT(S) IN L CELL TRANSFORMANTS International Journal of Immunogenetics. 13: 425-436. PMID 3624883 DOI: 10.1111/J.1744-313X.1986.Tb01127.X  0.349
1983 Weiss EH, Mellor AL, Golden L, Bud H, Hurst J, Flavell RA, Simpson E, James R, Townsend AR, Festenstein H. Structure and expression of class I genes of the mouse major histocompatibility complex. Haematology and Blood Transfusion. 28: 454-8. PMID 6862309 DOI: 10.1007/978-3-642-68761-7_87  0.339
1982 Mellor AL, Golden L, Weiss E, Bullman H, Hurst J, Simpson E, James RF, Townsend AR, Taylor PM, Schmidt W, Ferluga J, Leben L, Santamaria M, Atfield G, Festenstein H, et al. Expression of murine H-2Kb histocompatibility antigen in cells transformed with cloned H-2 genes. Nature. 298: 529-34. PMID 6285197 DOI: 10.1038/298529A0  0.36
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