Edwin K. Jackson - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Pharmacology, Cell Biology, Molecular Biology

293 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jackson EK, Tofovic SP, Chen Y, Birder LA. 8-Aminopurines in the Cardiovascular and Renal Systems and Beyond. Hypertension (Dallas, Tex. : 1979). PMID 37503660 DOI: 10.1161/HYPERTENSIONAHA.123.20582  0.31
2020 Jackson EK, Cheng D, Ritov VB, Mi Z. Alkaline Phosphatase Activity Is a Key Determinant of Vascular Responsiveness to Norepinephrine. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12015. PMID 32829665 DOI: 10.1161/Hypertensionaha.120.15822  0.368
2020 Ludwig N, Azambuja JH, Rao A, Gillespie DG, Jackson EK, Whiteside TL. Adenosine receptors regulate exosome production. Purinergic Signalling. PMID 32440820 DOI: 10.1007/S11302-020-09700-7  0.333
2020 Pettinger WA, Jackson EK. -Adrenoceptors: Challenges and Opportunities-Enlightenment from the Kidney. Cardiovascular Therapeutics. 2020: 2478781. PMID 32426035 DOI: 10.1155/2020/2478781  0.382
2020 Jackson EK, Gillespie DG, Cheng D, Mi Z, Menshikova EV. Characterization of the N-etheno-bridge method to assess extracellular metabolism of adenine nucleotides: detection of a possible role for purine nucleoside phosphorylase in adenosine metabolism. Purinergic Signalling. PMID 32367441 DOI: 10.1007/S11302-020-09699-X  0.303
2020 Ludwig N, Yerneni SS, Menshikova EV, Gillespie DG, Jackson EK, Whiteside TL. Simultaneous Inhibition of Glycolysis and Oxidative Phosphorylation Triggers a Multi-Fold Increase in Secretion of Exosomes: Possible Role of 2'3'-cAMP. Scientific Reports. 10: 6948. PMID 32332778 DOI: 10.1038/S41598-020-63658-5  0.359
2020 Jin K, Ma Y, Manrique-Caballero CL, Li H, Emlet DR, Li S, Baty CJ, Wen X, Kim-Campbell N, Frank A, Menchikova EV, Pastor-Soler NM, Hallows KR, Jackson EK, Shiva S, et al. Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32246808 DOI: 10.1096/Fj.201901900R  0.336
2020 Jackson EK, Gillespie DG, Tofovic SP. DPP4 Inhibition, NPY, PYY, SDF-1α and a Hypertensive Genetic Background Conspire to Augment Cell Proliferation and Collagen Production: Effects That Are Abolished by Low Concentrations of 2-Methoxyestradiol. The Journal of Pharmacology and Experimental Therapeutics. PMID 32015161 DOI: 10.1124/Jpet.119.263467  0.355
2019 Dubey RK, Baruscotti I, Stiller R, Fingerle J, Gillespie DG, Mi Z, Leeners B, Imthurn B, Rosselli M, Jackson EK. Adenosine, Via A Receptors, Inhibits Human (P-SMC) Progenitor Smooth Muscle Cell Growth. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 31786976 DOI: 10.1161/Hypertensionaha.119.13698  0.392
2019 Mihai MC, Popa MA, Suica VI, Antohe F, Jackson EK, Simionescu M, Dubey RK. Mechanism of 17β-estradiol stimulated integration of human mesenchymal stem cells in heart tissue. Journal of Molecular and Cellular Cardiology. PMID 31201797 DOI: 10.1016/J.Yjmcc.2019.06.007  0.326
2019 Salah E, Bastacky SI, Jackson EK, Tofovic SP. 2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury. Journal of Cardiovascular Pharmacology. 73: 165-177. PMID 30839510 DOI: 10.1097/Fjc.0000000000000649  0.383
2019 Jackson EK, Mi Z, Janesko-Feldman K, Jackson TC, Kochanek PM. 2',3'-cGMP Exists In Vivo and Comprises a 2',3'-cGMP-Guanosine Pathway. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30789788 DOI: 10.1152/Ajpregu.00401.2018  0.325
2019 Kurobe* M, Takaoka E, Suzuki T, Mizoguchi S, Saito T, Miyazaki J, Nishiyama H, Jackson EK, Birder LA, Yoshimura N. MP06-16 THE FUNCTIONAL ROLE OF ADENOSINE A2B RECEPTOR SUBTYPES IN THE BLADDER OF MALE RATS WITH BLADDER OUTLET OBSTRUCTION Journal of Urology. 201. DOI: 10.1097/01.Ju.0000555008.52074.A2  0.301
2018 Jackson EK, Mi Z, Kleyman TR, Cheng D. 8-Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1. Journal of the American Heart Association. 7: e010085. PMID 30608204 DOI: 10.1161/Jaha.118.010085  0.434
2018 Jackson TC, Kotermanski SE, Kochanek PM, Jackson EK. Oxidative Stress Induces Release of 2'-AMP from Microglia. Brain Research. PMID 30395838 DOI: 10.1016/J.Brainres.2018.11.002  0.304
2018 Jackson EK, Mi E, Ritov VB, Gillespie DG. Extracellular Ubiquitin(1-76) and Ubiquitin(1-74) Regulate Cardiac Fibroblast Proliferation. Hypertension (Dallas, Tex. : 1979). 72: 909-917. PMID 30354710 DOI: 10.1161/Hypertensionaha.118.11666  0.373
2018 Birder LA, Wolf-Johnston AS, Jackson EK, Wein AJ, Dmochowski R. Aging increases the expression of vasopressin receptors in both the kidney and urinary bladder. Neurourology and Urodynamics. PMID 30311671 DOI: 10.1002/Nau.23830  0.327
2018 Bilan V, Schneider F, Novelli EM, Kelley EE, Sriva S, Gladwin M, Jackson EK, Tofovic SP. EXPRESS: Experimental Intravascular Hemolysis Induces Hemodynamic and Pathological Pulmonary Hypertension - Association with Accelerated Purine Metabolism. Pulmonary Circulation. 2045894018791557. PMID 30003836 DOI: 10.1177/2045894018791557  0.305
2018 Jackson EK, Gillespie DG, Mi Z, Cheng D. Adenosine Receptors Influence Hypertension in Dahl Salt-Sensitive Rats: Dependence on Receptor Subtype, Salt Diet, and Sex. Hypertension (Dallas, Tex. : 1979). PMID 29941515 DOI: 10.1161/Hypertensionaha.117.10765  0.302
2018 Salah EM, Bastacky SI, Jackson EK, Tofovic SP. Captopril Attenuates Cardiovascular and Renal Disease in a Rat Model of Heart Failure With Preserved Ejection Fraction. Journal of Cardiovascular Pharmacology. 71: 205-214. PMID 29620605 DOI: 10.1097/Fjc.0000000000000561  0.357
2018 Jackson EK, Mi Z, Kleyman TR, Cheng D. Abstract 067: Mechanism of Action of 8-Aminoguanine on Renal Excretory Function Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.067  0.307
2017 Jackson EK, Zhang Y, Gillespie DD, Zhu X, Cheng D, Jackson TC. SDF-1α (Stromal Cell-Derived Factor 1α) Induces Cardiac Fibroblasts, Renal Microvascular Smooth Muscle Cells, and Glomerular Mesangial Cells to Proliferate, Cause Hypertrophy, and Produce Collagen. Journal of the American Heart Association. 6. PMID 29114002 DOI: 10.1161/Jaha.117.007253  0.349
2017 Keller AS, Diederich L, Panknin C, DeLalio LJ, Drake JC, Sherman R, Jackson EK, Yan Z, Kelm M, Cortese-Krott MM, Isakson BE. Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway. American Journal of Physiology. Cell Physiology. ajpcell.00178.2017. PMID 28855161 DOI: 10.1152/Ajpcell.00178.2017  0.322
2017 Long KR, Shipman KE, Rbaibi Y, Menshikova EV, Ritov VB, Eshbach ML, Jiang Y, Jackson EK, Baty CJ, Weisz OA. Proximal tubule apical endocytosis is modulated by fluid shear stress via an mTOR-dependent pathway. Molecular Biology of the Cell. PMID 28720662 DOI: 10.1091/Mbc.E17-04-0211  0.32
2017 Jackson EK, Kotermanski SE, Menshikova EV, Dubey RK, Jackson TC, Kochanek PM. Adenosine Production by Brain Cells. Journal of Neurochemistry. PMID 28294336 DOI: 10.1111/Jnc.14018  0.308
2017 Jackson EK, Zhang Y, Cheng D. Alkaline Phosphatase Inhibitors Attenuate Renovascular Responses to Norepinephrine. Hypertension (Dallas, Tex. : 1979). PMID 28137984 DOI: 10.1161/Hypertensionaha.116.08623  0.386
2017 Zhu X, Jackson EK. RACK1 Regulates Angiotensin II-Induced Contractions of SHR Preglomerular Vascular Smooth Muscle Cells. American Journal of Physiology. Renal Physiology. ajprenal.00547.2016. PMID 28100502 DOI: 10.1152/Ajprenal.00547.2016  0.38
2016 Jackson EK, Gillespie DG, Mi Z. 8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric and Antihypertensive Activity. The Journal of Pharmacology and Experimental Therapeutics. PMID 27679494 DOI: 10.1124/Jpet.116.237552  0.332
2016 Schaufelberger SA, Rosselli M, Barchiesi F, Gillespie DG, Jackson EK, Dubey RK. 2-Methoxyestradiol, an Endogenous 17β-Estradiol Metabolite, Inhibits Microglial Proliferation and Activation via an Estrogen Receptor-Independent Mechanism. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00418.2015. PMID 26732685 DOI: 10.1152/Ajpendo.00418.2015  0.394
2016 Jackson EK. Discovery and Roles of 2',3'-cAMP in Biological Systems. Handbook of Experimental Pharmacology. PMID 26721674 DOI: 10.1007/164_2015_40  0.38
2015 Tofovic SP, Salah EM, Smits GJ, Whalley ET, Ticho B, Deykin A, Jackson EK. Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction. The Journal of Pharmacology and Experimental Therapeutics. PMID 26585572 DOI: 10.1124/Jpet.115.228841  0.355
2015 Jackson EK, Menshikova EV, Mi Z, Verrier JD, Bansal R, Janesko-Feldman K, Jackson TC, Kochanek PM. Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion. Journal of the American Society of Nephrology : Jasn. PMID 26574047 DOI: 10.1681/Asn.2015040397  0.347
2015 Rigassi L, Bozzolo FB, Lucchinetti E, Zaugg M, Fingerle J, Rosselli M, Imthurn B, Jackson EK, Dubey RK. 2-Methoxyestradiol Blocks the RhoA/ROCK1 Pathway in Human Aortic Smooth Muscle Cells. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00267.2015. PMID 26487003 DOI: 10.1152/Ajpendo.00267.2015  0.343
2015 Dubey RK, Fingerle J, Gillespie DG, Mi Z, Rosselli M, Imthurn B, Jackson EK. Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D. Hypertension. PMID 26416848 DOI: 10.1161/Hypertensionaha.115.05912  0.37
2015 Zhu X, Gillespie DG, Jackson EK. NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1528-42. PMID 26371160 DOI: 10.1152/Ajpheart.00070.2015  0.372
2015 Rahaman MM, Reinders FG, Koes D, Nguyen AT, Mutchler SM, Sparacino-Watkins C, Alvarez RA, Miller MP, Cheng D, Chen BB, Jackson EK, Camacho CJ, Straub AC. Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 that Increase Nitric Oxide Bioavailability. The Journal of Biological Chemistry. PMID 26001785 DOI: 10.1074/Jbc.M114.629964  0.348
2015 Verrier JD, Kochanek PM, Jackson EK. Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP. The Journal of Pharmacology and Experimental Therapeutics. 354: 175-83. PMID 25998049 DOI: 10.1124/Jpet.115.225219  0.349
2015 Hatfield SM, Kjaergaard J, Lukashev D, Schreiber TH, Belikoff B, Abbott R, Sethumadhavan S, Philbrook P, Ko K, Cannici R, Thayer M, Rodig S, Kutok JL, Jackson EK, Karger B, et al. Immunological mechanisms of the antitumor effects of supplemental oxygenation. Science Translational Medicine. 7: 277ra30. PMID 25739764 DOI: 10.1126/Scitranslmed.Aaa1260  0.307
2015 Miller RL, Denny GO, Knuepfer MM, Kleyman TR, Jackson EK, Salkoff LB, Loewy AD. Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema. Brain Research. 1601: 40-51. PMID 25557402 DOI: 10.1016/J.Brainres.2014.12.048  0.32
2015 Newell EA, Exo JL, Verrier JD, Jackson TC, Gillespie DG, Janesko-Feldman K, Kochanek PM, Jackson EK. 2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors. Brain Research. 1594: 27-35. PMID 25451117 DOI: 10.1016/J.Brainres.2014.10.059  0.353
2015 Jackson EK, Mi Z, Tofovic SP, Gillespie DG. Effect of dipeptidyl peptidase 4 inhibition on arterial blood pressure is context dependent. Hypertension. 65: 238-49. PMID 25368027 DOI: 10.1161/Hypertensionaha.114.04631  0.368
2014 Wei Y, Liao Y, Zavilowitz B, Ren J, Liu W, Chan P, Rohatgi R, Estilo G, Jackson EK, Wang WH, Satlin LM. Angiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptation. American Journal of Physiology. Renal Physiology. 307: F833-43. PMID 25100281 DOI: 10.1152/Ajprenal.00141.2014  0.346
2014 Jackson EK, Mi Z. The guanosine-adenosine interaction exists in vivo. The Journal of Pharmacology and Experimental Therapeutics. 350: 719-26. PMID 25002416 DOI: 10.1124/Jpet.114.216978  0.308
2014 Jackson EK, Cheng D, Verrier JD, Janesko-Feldman K, Kochanek PM. Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP. American Journal of Physiology. Renal Physiology. 307: F680-5. PMID 24990899 DOI: 10.1152/Ajprenal.00312.2014  0.309
2014 Jackson EK, Cheng D, Mi Z, Gillespie DG. Guanosine regulates adenosine levels in the kidney. Physiological Reports. 2. PMID 24872359 DOI: 10.14814/Phy2.12028  0.334
2014 Jackson EK, Gillespie DG, Mi Z, Cheng D, Bansal R, Janesko-Feldman K, Kochanek PM. Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway. American Journal of Physiology. Renal Physiology. 307: F14-24. PMID 24808540 DOI: 10.1152/Ajprenal.00134.2014  0.405
2013 Jackson EK, Cheng D, Mi Z, Verrier JD, Janesko-Feldman K, Kochanek PM. Role of CD73 in Renal Sympathetic Neurotransmission in the Mouse Kidney. Physiological Reports. 1. PMID 24066228 DOI: 10.1002/Phy2.57  0.323
2013 Jackson TC, Verrier JD, Drabek T, Janesko-Feldman K, Gillespie DG, Uray T, Dezfulian C, Clark RS, Bayir H, Jackson EK, Kochanek PM. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes. The Journal of Pharmacology and Experimental Therapeutics. 347: 516-28. PMID 24023368 DOI: 10.1124/Jpet.113.206888  0.323
2013 Jackson EK, Gillespie DG. Regulation of Cell Proliferation by the Guanosine-Adenosine Mechanism: Role of Adenosine Receptors. Physiological Reports. 1: e00024. PMID 23956837 DOI: 10.1002/Phy2.24  0.372
2013 Verrier JD, Jackson TC, Gillespie DG, Janesko-Feldman K, Bansal R, Goebbels S, Nave KA, Kochanek PM, Jackson EK. Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway. Glia. 61: 1595-606. PMID 23922219 DOI: 10.1002/Glia.22523  0.345
2013 Whiteside TL, Jackson EK. Adenosine and prostaglandin e2 production by human inducible regulatory T cells in health and disease. Frontiers in Immunology. 4: 212. PMID 23898333 DOI: 10.3389/Fimmu.2013.00212  0.321
2013 Jackson EK, Mi Z. In vivo cardiovascular pharmacology of 2',3'-cAMP, 2'-AMP, and 3'-AMP in the rat. The Journal of Pharmacology and Experimental Therapeutics. 346: 190-200. PMID 23759508 DOI: 10.1124/Jpet.113.205757  0.43
2013 Kochanek PM, Dixon CE, Shellington DK, Shin SS, Bay?r H, Jackson EK, Kagan VE, Yan HQ, Swauger PV, Parks SA, Ritzel DV, Bauman R, Clark RS, Garman RH, Bandak F, et al. Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats. Journal of Neurotrauma. 30: 920-37. PMID 23496248 DOI: 10.1089/Neu.2013.2862  0.307
2013 Cheng D, Zhu X, Gillespie DG, Jackson EK. Role of RACK1 in the differential proliferative effects of neuropeptide Y(1-36) and peptide YY(1-36) in SHR vs. WKY preglomerular vascular smooth muscle cells. American Journal of Physiology. Renal Physiology. 304: F770-80. PMID 23303411 DOI: 10.1152/Ajprenal.00646.2012  0.383
2013 Jackson EK, Cheng D, Jackson TC, Verrier JD, Gillespie DG. Extracellular guanosine regulates extracellular adenosine levels. American Journal of Physiology. Cell Physiology. 304: C406-21. PMID 23242185 DOI: 10.1152/Ajpcell.00212.2012  0.411
2013 Jackson EK, Gillespie DG. Extracellular 2',3'-cAMP-adenosine pathway in proximal tubular, thick ascending limb, and collecting duct epithelial cells. American Journal of Physiology. Renal Physiology. 304: F49-55. PMID 23077101 DOI: 10.1152/Ajprenal.00571.2012  0.394
2012 Choukèr A, Ohta A, Martignoni A, Lukashev D, Zacharia LC, Jackson EK, Schnermann J, Ward JM, Kaufmann I, Klaunberg B, Sitkovsky MV, Thiel M. In vivo hypoxic preconditioning protects from warm liver ischemia-reperfusion injury through the adenosine A2B receptor. Transplantation. 94: 894-902. PMID 23073466 DOI: 10.1097/Tp.0B013E31826A9A46  0.639
2012 Jackson EK, Cheng D, Mi Z, Verrier JD, Janesko-Feldman K, Kochanek PM. Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney. American Journal of Physiology. Renal Physiology. 303: F1000-5. PMID 22874760 DOI: 10.1152/Ajprenal.00363.2012  0.318
2012 Jackson EK, Kochanek SJ, Gillespie DG. Dipeptidyl peptidase IV regulates proliferation of preglomerular vascular smooth muscle and mesangial cells. Hypertension. 60: 757-64. PMID 22802229 DOI: 10.1161/Hypertensionaha.112.196501  0.357
2012 Jackson EK, Gillespie DG. Extracellular 2',3'-cAMP and 3',5'-cAMP stimulate proliferation of preglomerular vascular endothelial cells and renal epithelial cells. American Journal of Physiology. Renal Physiology. 303: F954-62. PMID 22791337 DOI: 10.1152/Ajprenal.00335.2012  0.397
2012 Prakasam HS, Herrington H, Roppolo JR, Jackson EK, Apodaca G. Modulation of bladder function by luminal adenosine turnover and A1 receptor activation. American Journal of Physiology. Renal Physiology. 303: F279-92. PMID 22552934 DOI: 10.1152/Ajprenal.00566.2011  0.373
2012 Verrier JD, Jackson TC, Bansal R, Kochanek PM, Puccio AM, Okonkwo DO, Jackson EK. The brain in vivo expresses the 2',3'-cAMP-adenosine pathway. Journal of Neurochemistry. 122: 115-25. PMID 22360621 DOI: 10.1111/J.1471-4159.2012.07705.X  0.323
2012 Jackson EK, Cheng D, Tofovic SP, Mi Z. Endogenous adenosine contributes to renal sympathetic neurotransmission via postjunctional A1 receptor-mediated coincident signaling. American Journal of Physiology. Renal Physiology. 302: F466-76. PMID 22114202 DOI: 10.1152/Ajprenal.00495.2011  0.412
2011 Jackson EK. The 2',3'-cAMP-adenosine pathway. American Journal of Physiology. Renal Physiology. 301: F1160-7. PMID 21937608 DOI: 10.1152/Ajprenal.00450.2011  0.398
2011 Cheng D, Zhu X, Barchiesi F, Gillespie DG, Dubey RK, Jackson EK. Receptor for activated protein kinase C1 regulates cell proliferation by modulating calcium signaling. Hypertension. 58: 689-95. PMID 21844488 DOI: 10.1161/Hypertensionaha.111.174508  0.382
2011 Verrier JD, Exo JL, Jackson TC, Ren J, Gillespie DG, Dubey RK, Kochanek PM, Jackson EK. Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia. Journal of Neurochemistry. 118: 979-87. PMID 21777245 DOI: 10.1111/J.1471-4159.2011.07392.X  0.351
2011 Jackson EK, Ren J, Cheng D, Mi Z. Extracellular cAMP-adenosine pathways in the mouse kidney. American Journal of Physiology. Renal Physiology. 301: F565-73. PMID 21653635 DOI: 10.1152/Ajprenal.00094.2011  0.395
2011 Jackson EK, Ren J, Gillespie DG. 2',3'-cAMP, 3'-AMP, and 2'-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors. American Journal of Physiology. Heart and Circulatory Physiology. 301: H391-401. PMID 21622827 DOI: 10.1152/Ajpheart.00336.2011  0.432
2011 Jackson EK. Role of sphingosine-1-phosphate in the renal medulla. American Journal of Physiology. Renal Physiology. 301: F33-4. PMID 21511695 DOI: 10.1152/Ajprenal.00207.2011  0.314
2011 Jackson EK, Gillespie DG, Dubey RK. 2'-AMP and 3'-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. The Journal of Pharmacology and Experimental Therapeutics. 337: 444-50. PMID 21270135 DOI: 10.1124/Jpet.110.178137  0.393
2011 Su Y, Jackson EK, Gorelik E. Receptor desensitization and blockade of the suppressive effects of prostaglandin E(2) and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes. Cancer Immunology, Immunotherapy : Cii. 60: 111-22. PMID 20960188 DOI: 10.1007/S00262-010-0924-Z  0.35
2010 Cheng D, Ren J, Gillespie DG, Mi Z, Jackson EK. Regulation of 3',5'-cAMP in preglomerular smooth muscle and endothelial cells from genetically hypertensive rats. Hypertension. 56: 1096-101. PMID 20975032 DOI: 10.1161/Hypertensionaha.110.160176  0.401
2010 Barchiesi F, Lucchinetti E, Zaugg M, Ogunshola OO, Wright M, Meyer M, Rosselli M, Schaufelberger S, Gillespie DG, Jackson EK, Dubey RK. Candidate genes and mechanisms for 2-methoxyestradiol-mediated vasoprotection. Hypertension. 56: 964-72. PMID 20921434 DOI: 10.1161/Hypertensionaha.110.152298  0.344
2010 Tofovic SP, Jones TJ, Bilan VP, Jackson EK, Petrusevska G. Synergistic therapeutic effects of 2-methoxyestradiol with either sildenafil or bosentan on amelioration of monocrotaline-induced pulmonary hypertension and vascular remodeling. Journal of Cardiovascular Pharmacology. 56: 475-83. PMID 20881615 DOI: 10.1097/Fjc.0B013E3181F215E7  0.354
2010 Jackson EK. Dipeptidyl peptidase IV inhibition alters the hemodynamic response to angiotensin-converting enzyme inhibition in humans with the metabolic syndrome. Hypertension. 56: 581-3. PMID 20679176 DOI: 10.1161/Hypertensionaha.110.158527  0.303
2010 Baruscotti I, Barchiesi F, Jackson EK, Imthurn B, Stiller R, Kim JH, Schaufelberger S, Rosselli M, Hughes CC, Dubey RK. Estradiol stimulates capillary formation by human endothelial progenitor cells: role of estrogen receptor-{alpha}/{beta}, heme oxygenase 1, and tyrosine kinase. Hypertension. 56: 397-404. PMID 20644008 DOI: 10.1161/Hypertensionaha.110.153262  0.386
2010 Mandapathil M, Szczepanski MJ, Szajnik M, Ren J, Jackson EK, Johnson JT, Gorelik E, Lang S, Whiteside TL. Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cells. The Journal of Biological Chemistry. 285: 27571-80. PMID 20558731 DOI: 10.1074/Jbc.M110.127100  0.341
2010 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Imthurn B, Rosselli M. Resveratrol, a red wine constituent, blocks the antimitogenic effects of estradiol on human female coronary artery smooth muscle cells. The Journal of Clinical Endocrinology and Metabolism. 95: E9-17. PMID 20534756 DOI: 10.1210/Jc.2010-0460  0.699
2010 Jackson EK, Ren J, Gillespie DG, Dubey RK. Extracellular 2,3-cyclic adenosine monophosphate is a potent inhibitor of preglomerular vascular smooth muscle cell and mesangial cell growth [corrected]. Hypertension. 56: 151-8. PMID 20516392 DOI: 10.1161/Hypertensionaha.110.152454  0.405
2010 Tofovic DS, Bilan VP, Jackson EK. Sitagliptin augments angiotensin II-induced renal vasoconstriction in kidneys from rats with metabolic syndrome. Clinical and Experimental Pharmacology & Physiology. 37: 689-91. PMID 20374254 DOI: 10.1111/J.1440-1681.2010.05389.X  0.366
2010 Dubey RK, Rosselli M, Gillespie DG, Mi Z, Jackson EK. Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth. The Journal of Pharmacology and Experimental Therapeutics. 333: 808-15. PMID 20194527 DOI: 10.1124/Jpet.110.166371  0.426
2010 Haselkorn ML, Shellington DK, Jackson EK, Vagni VA, Janesko-Feldman K, Dubey RK, Gillespie DG, Cheng D, Bell MJ, Jenkins LW, Homanics GE, Schnermann J, Kochanek PM. Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice. Journal of Neurotrauma. 27: 901-10. PMID 20121416 DOI: 10.1089/Neu.2009.1075  0.307
2010 Cheng D, Ren J, Jackson EK. Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells. Clinical and Experimental Pharmacology & Physiology. 37: 205-7. PMID 19671067 DOI: 10.1111/J.1440-1681.2009.05272.X  0.35
2009 Jackson EK, Ren J, Mi Z. Extracellular 2',3'-cAMP is a source of adenosine. The Journal of Biological Chemistry. 284: 33097-106. PMID 19801686 DOI: 10.1074/Jbc.M109.053876  0.413
2009 Dubey RK, Jackson EK. Potential vascular actions of 2-methoxyestradiol. Trends in Endocrinology and Metabolism: Tem. 20: 374-9. PMID 19734053 DOI: 10.1016/J.Tem.2009.04.007  0.343
2009 Tofovic SP, Zhang X, Jackson EK, Zhu H, Petrusevska G. 2-methoxyestradiol attenuates bleomycin-induced pulmonary hypertension and fibrosis in estrogen-deficient rats. Vascular Pharmacology. 51: 190-7. PMID 19540933 DOI: 10.1016/J.Vph.2009.06.002  0.309
2009 Jackson EK, Mi Z. Regulation of renovascular adenosine 3',5'-cyclic monophosphate in spontaneously hypertensive rats. Hypertension. 54: 270-7. PMID 19528365 DOI: 10.1161/Hypertensionaha.109.130542  0.4
2009 Tofovic SP, Jackson EK, Rafikova O. Adenosine deaminase-adenosine pathway in hemolysis-associated pulmonary hypertension. Medical Hypotheses. 72: 713-9. PMID 19237250 DOI: 10.1016/J.Mehy.2008.12.043  0.313
2009 Rajakariar R, Newson J, Jackson EK, Sawmynaden P, Smith A, Rahman F, Yaqoob MM, Gilroy DW. Nonresolving inflammation in gp91phox-/- mice, a model of human chronic granulomatous disease, has lower adenosine and cyclic adenosine 5'-monophosphate. Journal of Immunology (Baltimore, Md. : 1950). 182: 3262-9. PMID 19234224 DOI: 10.4049/Jimmunol.0801739  0.312
2009 Ren J, Mi Z, Stewart NA, Jackson EK. Identification and quantification of 2',3'-cAMP release by the kidney. The Journal of Pharmacology and Experimental Therapeutics. 328: 855-65. PMID 19033554 DOI: 10.1124/Jpet.108.146712  0.413
2008 Jackson EK, Mi Z. Sitagliptin augments sympathetic enhancement of the renovascular effects of angiotensin II in genetic hypertension. Hypertension. 51: 1637-42. PMID 18443229 DOI: 10.1161/Hypertensionaha.108.112532  0.383
2008 Tofovic SP, Zhang X, Zhu H, Jackson EK, Rafikova O, Petrusevska G. 2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling. Vascular Pharmacology. 48: 174-83. PMID 18373958 DOI: 10.1016/J.Vph.2008.02.001  0.374
2008 Su Y, Huang X, Raskovalova T, Zacharia L, Lokshin A, Jackson E, Gorelik E. Cooperation of adenosine and prostaglandin E2 (PGE2) in amplification of cAMP-PKA signaling and immunosuppression. Cancer Immunology, Immunotherapy : Cii. 57: 1611-23. PMID 18327580 DOI: 10.1007/S00262-008-0494-5  0.663
2008 Ren J, Mi Z, Jackson EK. Assessment of nerve stimulation-induced release of purines from mouse kidneys by tandem mass spectrometry. The Journal of Pharmacology and Experimental Therapeutics. 325: 920-6. PMID 18322147 DOI: 10.1124/Jpet.108.137752  0.348
2008 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Wunder D, Imthurn B, Rosselli M. Medroxyprogesterone abrogates the inhibitory effects of estradiol on vascular smooth muscle cells by preventing estradiol metabolism. Hypertension. 51: 1197-202. PMID 18259021 DOI: 10.1161/Hypertensionaha.107.106575  0.698
2008 Jackson EK, Gillespie DG, Zhu C, Ren J, Zacharia LC, Mi Z. Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA. Hypertension. 51: 719-26. PMID 18250367 DOI: 10.1161/Hypertensionaha.107.096297  0.698
2008 Jackson EK, Mi Z. Regulation of renal ectophosphodiesterase by protein kinase C and sodium diet. The Journal of Pharmacology and Experimental Therapeutics. 325: 210-6. PMID 18223197 DOI: 10.1124/Jpet.107.134445  0.408
2008 Sonalker PA, Tofovic SP, Bastacky SI, Jackson EK. Chronic noradrenaline increases renal expression of NHE-3, NBC-1, BSC-1 and aquaporin-2. Clinical and Experimental Pharmacology & Physiology. 35: 594-600. PMID 18177483 DOI: 10.1111/J.1440-1681.2007.04846.X  0.786
2008 Jackson EK, Dubinion JH, Mi Z. Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure. Clinical and Experimental Pharmacology & Physiology. 35: 29-34. PMID 18047624 DOI: 10.1111/J.1440-1681.2007.04737.X  0.778
2008 TOFOVIC S, SALAH E, SMITS G, WHALLEY E, TICHO B, JACKSON E. Chronic adenosine receptor blockade with BG9928 attenuates cardiac and renal histopathology and improves diabetes in animals with the metabolic syndrome European Journal of Heart Failure Supplements. 7: 109-110. DOI: 10.1016/S1567-4215(08)60302-1  0.33
2007 Tofovic SP, Salah EM, Jackson EK, Melhem M. Early renal injury induced by caffeine consumption in obese, diabetic ZSF1 rats. Renal Failure. 29: 891-902. PMID 17994459 DOI: 10.1080/08860220701569846  0.396
2007 Sonalker PA, Tofovic SP, Jackson EK. Cellular distribution of the renal bumetanide-sensitive Na-K-2Cl cotransporter BSC-1 in the inner stripe of the outer medulla during the development of hypertension in the spontaneously hypertensive rat. Clinical and Experimental Pharmacology & Physiology. 34: 1307-12. PMID 17973873 DOI: 10.1111/J.1440-1681.2007.04747.X  0.783
2007 Jackson EK, Zhang M, Liu W, Mi Z. Inhibition of renal dipeptidyl peptidase IV enhances peptide YY1-36-induced potentiation of angiotensin II-mediated renal vasoconstriction in spontaneously hypertensive rats. The Journal of Pharmacology and Experimental Therapeutics. 323: 431-7. PMID 17726157 DOI: 10.1124/Jpet.107.126847  0.371
2007 Raskovalova T, Lokshin A, Huang X, Su Y, Mandic M, Zarour HM, Jackson EK, Gorelik E. Inhibition of cytokine production and cytotoxic activity of human antimelanoma specific CD8+ and CD4+ T lymphocytes by adenosine-protein kinase A type I signaling Cancer Research. 67: 5949-5956. PMID 17575165 DOI: 10.1158/0008-5472.Can-06-4249  0.326
2007 Sonalker PA, Jackson EK. Norepinephrine, via beta-adrenoceptors, regulates bumetanide-sensitive cotransporter type 1 expression in thick ascending limb cells. Hypertension. 49: 1351-7. PMID 17438304 DOI: 10.1161/Hypertensionaha.107.088732  0.787
2007 Funakoshi H, Zacharia LC, Tang Z, Zhang J, Lee LL, Good JC, Herrmann DE, Higuchi Y, Koch WJ, Jackson EK, Chan TO, Feldman AM. A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction. Circulation. 115: 2307-15. PMID 17438146 DOI: 10.1161/Circulationaha.107.694596  0.676
2007 Bhanu NV, Aerbajinai W, Gantt NM, Jackson EK, Goh SH, Terry Lee Y, Miller JL. Cl-IB-MECA inhibits human erythropoiesis. British Journal of Haematology. 137: 233-6. PMID 17408462 DOI: 10.1111/J.1365-2141.2007.06540.X  0.318
2007 Jackson EK, Mi Z, Zacharia LC, Tofovic SP, Dubey RK. The pancreatohepatorenal cAMP-adenosine mechanism. The Journal of Pharmacology and Experimental Therapeutics. 321: 799-809. PMID 17314200 DOI: 10.1124/Jpet.106.119164  0.716
2007 Jackson EK, Gillespie DG, Jackson TC. Phospholipase C and Src modulate angiotensin II-induced cyclic AMP production in preglomerular microvascular smooth-muscle cells from spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. 49: 106-10. PMID 17312452 DOI: 10.1097/Fjc.0B013E31802Ee3D5  0.351
2007 Jackson EK, Ren J, Zacharia LC, Mi Z. Characterization of renal ecto-phosphodiesterase. The Journal of Pharmacology and Experimental Therapeutics. 321: 810-5. PMID 17308037 DOI: 10.1124/Jpet.106.119057  0.705
2007 Jackson TC, Mi Z, Bastacky SI, McHale T, Melhem MF, Sonalker PA, Tofovic SP, Jackson EK. PPAR alpha agonists improve renal preservation in kidneys subjected to chronic in vitro perfusion: interaction with mannitol. Transplant International : Official Journal of the European Society For Organ Transplantation. 20: 277-90. PMID 17291221 DOI: 10.1111/J.1432-2277.2006.00431.X  0.799
2007 Zhang X, Jia Y, Jackson EK, Tofovic SP. 2-Methoxyestradiol and 2-ethoxyestradiol retard the progression of renal disease in aged, obese, diabetic ZSF1 rats Journal of Cardiovascular Pharmacology. 49: 56-63. PMID 17261964 DOI: 10.1097/Fjc.0B013E31802Cb88E  0.36
2007 Jackson EK, Mi Z, Dubey RK. The extracellular cAMP-adenosine pathway significantly contributes to the in vivo production of adenosine Journal of Pharmacology and Experimental Therapeutics. 320: 117-123. PMID 17028245 DOI: 10.1124/Jpet.106.112748  0.412
2006 Raskovalova T, Lokshin A, Huang X, Jackson EK, Gorelik E. Adenosine-mediated inhibition of cytotoxic activity and cytokine production by IL-2/NKp46-activated NK cells: Involvement of protein kinase A isozyme I (PKA I) Immunologic Research. 36: 91-99. PMID 17337770 DOI: 10.1385/Ir:36:1:91  0.353
2006 Zacharia LC, Jackson EK, Kloosterboer HJ, Imthurn B, Dubey RK. Conversion of tibolone to 7alpha-methyl-ethinyl estradiol using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry: interpretation and clinical implications. Menopause (New York, N.Y.). 13: 926-34. PMID 17006378 DOI: 10.1097/01.Gme.0000227331.49081.D7  0.644
2006 Forman MB, Stone GW, Jackson EK. Role of adenosine as adjunctive therapy in acute myocardial infarction Cardiovascular Drug Reviews. 24: 116-147. PMID 16961725 DOI: 10.1111/J.1527-3466.2006.00116.X  0.311
2006 Arendash GW, Schleif W, Rezai-Zadeh K, Jackson EK, Zacharia LC, Cracchiolo JR, Shippy D, Tan J. Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production. Neuroscience. 142: 941-52. PMID 16938404 DOI: 10.1016/J.Neuroscience.2006.07.021  0.649
2006 Ohta A, Gorelik E, Prasad SJ, Ronchese F, Lukashev D, Wong MK, Huang X, Caldwell S, Liu K, Smith P, Chen JF, Jackson EK, Apasov S, Abrams S, Sitkovsky M. A2A adenosine receptor protects tumors from antitumor T cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 13132-7. PMID 16916931 DOI: 10.1073/Pnas.0605251103  0.302
2006 Lokshin A, Raskovalova T, Huang X, Zacharia LC, Jackson EK, Gorelik E. Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells. Cancer Research. 66: 7758-65. PMID 16885379 DOI: 10.1158/0008-5472.Can-06-0478  0.689
2006 Tofovic SP, Zhang X, Jackson EK, Dacic S, Petrusevska G. 2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension Vascular Pharmacology. 45: 358-367. PMID 16872912 DOI: 10.1016/J.Vph.2006.05.007  0.317
2006 Barchiesi F, Jackson EK, Fingerle J, Gillespie DG, Odermatt B, Dubey RK. 2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle. Circulation Research. 99: 266-74. PMID 16794187 DOI: 10.1161/01.Res.0000233318.85181.2E  0.372
2006 Yu W, Zacharia LC, Jackson EK, Apodaca G. Adenosine receptor expression and function in bladder uroepithelium. American Journal of Physiology. Cell Physiology. 291: C254-65. PMID 16571869 DOI: 10.1152/Ajpcell.00025.2006  0.682
2006 Dubinion JH, Mi Z, Jackson EK. Role of renal sympathetic nerves in regulating renovascular responses to angiotensin II in spontaneously hypertensive rats. The Journal of Pharmacology and Experimental Therapeutics. 317: 1330-6. PMID 16537795 DOI: 10.1124/Jpet.106.101279  0.795
2006 Jackson EK, Zacharia LC, Zhang M, Gillespie DG, Zhu C, Dubey RK. cAMP-adenosine pathway in the proximal tubule. The Journal of Pharmacology and Experimental Therapeutics. 317: 1219-29. PMID 16527902 DOI: 10.1124/Jpet.106.101360  0.711
2006 Dubinion JH, Mi Z, Zhu C, Gao L, Jackson EK. Pancreatic polypeptide-fold peptide receptors and angiotensin II-induced renal vasoconstriction. Hypertension. 47: 545-51. PMID 16365188 DOI: 10.1161/01.Hyp.0000197033.54756.83  0.794
2005 Raskovalova T, Huang X, Sitkovsky M, Zacharia LC, Jackson EK, Gorelik E. Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 4383-91. PMID 16177079 DOI: 10.4049/Jimmunol.175.7.4383  0.7
2005 Jackson EK. Putting the brakes on renin release: Role of the A1 receptor Hypertension. 46: 649-651. PMID 16172431 DOI: 10.1161/01.Hyp.0000184106.99949.88  0.345
2005 Tofovic SP, Salah EM, Mady HH, Jackson EK, Melhem MF. Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats Journal of Cardiovascular Pharmacology. 46: 430-437. PMID 16160593 DOI: 10.1097/01.Fjc.0000175878.32920.17  0.326
2005 Dubey RK, Gillespie DG, Mi Z, Jackson EK. Adenosine inhibits PDGF-induced growth of human glomerular mesangial cells via A(2B) receptors. Hypertension. 46: 628-34. PMID 16103269 DOI: 10.1161/01.Hyp.0000178464.63393.88  0.401
2005 Tofovic SP, Salah EM, Dubey RK, Melhem MF, Jackson EK. Estradiol metabolites attenuate renal and cardiovascular injury induced by chronic nitric oxide synthase inhibition Journal of Cardiovascular Pharmacology. 46: 25-35. PMID 15965351 DOI: 10.1097/01.Fjc.0000162765.89437.Ae  0.424
2005 Kochanek PM, Hendrich KS, Jackson EK, Wisniewski SR, Melick JA, Shore PM, Janesko KL, Zacharia L, Ho C. Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 1596-612. PMID 15931163 DOI: 10.1038/Sj.Jcbfm.9600154  0.684
2005 Jackson EK, Gao L, Zhu C. Mechanism of the vascular angiotensin II/alpha2-adrenoceptor interaction. The Journal of Pharmacology and Experimental Therapeutics. 314: 1109-16. PMID 15901799 DOI: 10.1124/Jpet.105.086074  0.378
2005 Jackson EK, Andresen BT, Seasholtz TM, Zhu C, Romero GG. Enhanced activation of RhoA by angiotensin II in SHR preglomerular microvascular smooth muscle cells. Journal of Cardiovascular Pharmacology. 45: 283-5. PMID 15772513 DOI: 10.1097/01.Fjc.0000155383.83927.9F  0.391
2005 Andresen BT, Shome K, Jackson EK, Romero GG. AT2 receptors cross talk with AT1 receptors through a nitric oxide- and RhoA-dependent mechanism resulting in decreased phospholipase D activity. American Journal of Physiology. Renal Physiology. 288: F763-70. PMID 15572519 DOI: 10.1152/Ajprenal.00323.2004  0.364
2005 Dubey RK, Jackson EK, Gillespie DG, Rosselli M, Barchiesi F, Krust A, Keller H, Zacharia LC, Imthurn B. Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast. The Journal of Clinical Endocrinology and Metabolism. 90: 247-55. PMID 15507517 DOI: 10.1210/Jc.2003-032154  0.694
2004 Jackson EK. Intraperitoneal administration of adenosine inhibits formation of abdominal adhesions Diseases of the Colon and Rectum. 47: 1390-1396. PMID 15484355 DOI: 10.1007/S10350-004-0578-Z  0.342
2004 Dubey RK, Imthurn B, Zacharia LC, Jackson EK. Hormone replacement therapy and cardiovascular disease: what went wrong and where do we go from here? Hypertension. 44: 789-95. PMID 15477384 DOI: 10.1161/01.Hyp.0000145988.95551.28  0.639
2004 Sonalker PA, Tofovic SP, Jackson EK. Increased expression of the sodium transporter BSC-1 in spontaneously hypertensive rats. The Journal of Pharmacology and Experimental Therapeutics. 311: 1052-61. PMID 15340004 DOI: 10.1124/Jpet.104.071209  0.771
2004 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Imthurn B. Catecholamines block the antimitogenic effect of estradiol on human coronary artery smooth muscle cells. The Journal of Clinical Endocrinology and Metabolism. 89: 3922-31. PMID 15292328 DOI: 10.1210/Jc.2004-0115  0.71
2004 Zacharia LC, Dubey RK, Jackson EK. A gas chromatography/mass spectrometry assay to measure estradiol, catecholestradiols, and methoxyestradiols in plasma. Steroids. 69: 255-61. PMID 15183691 DOI: 10.1016/J.Steroids.2004.01.005  0.648
2004 Barchiesi F, Jackson EK, Imthurn B, Fingerle J, Gillespie DG, Dubey RK. Differential Regulation of Estrogen Receptor Subtypes α and β in Human Aortic Smooth Muscle Cells by Oligonucleotides and Estradiol Journal of Clinical Endocrinology and Metabolism. 89: 2373-2381. PMID 15126566 DOI: 10.1210/Jc.2003-030821  0.337
2004 Jackson TC, Mi Z, Jackson EK. Modulation of cyclic AMP production by signal transduction pathways in preglomerular microvessels and microvascular smooth muscle cells. The Journal of Pharmacology and Experimental Therapeutics. 310: 349-58. PMID 15087474 DOI: 10.1124/Jpet.103.063081  0.351
2004 Jackson EK, Raghvendra DK. The extracellular cyclic AMP-adenosine pathway in renal physiology Annual Review of Physiology. 66: 571-599. PMID 14977414 DOI: 10.1146/Annurev.Physiol.66.032102.111604  0.401
2004 Zacharia LC, Piché CA, Fielding RM, Holland KM, Allison SD, Dubey RK, Jackson EK. 2-hydroxyestradiol is a prodrug of 2-methoxyestradiol. The Journal of Pharmacology and Experimental Therapeutics. 309: 1093-7. PMID 14872091 DOI: 10.1124/Jpet.103.062505  0.659
2004 Andresen BT, Romero GG, Jackson EK. AT2 receptors attenuate AT1 receptor-induced phospholipase D activation in vascular smooth muscle cells. The Journal of Pharmacology and Experimental Therapeutics. 309: 425-31. PMID 14722318 DOI: 10.1124/Jpet.103.061846  0.394
2004 Dubey RK, Tofovic SP, Jackson EK. Cardiovascular Pharmacology of Estradiol Metabolites Journal of Pharmacology and Experimental Therapeutics. 308: 403-409. PMID 14657266 DOI: 10.1124/Jpet.103.058057  0.412
2003 Zacharia LC, Gogos JA, Karayiorgou M, Jackson EK, Gillespie DG, Barchiesi F, Dubey RK. Methoxyestradiols mediate the antimitogenic effects of 17beta-estradiol: direct evidence from catechol-O-methyltransferase-knockout mice. Circulation. 108: 2974-8. PMID 14662705 DOI: 10.1161/01.Cir.0000106900.66354.30  0.699
2003 Jackson EK, Herzer WA. Renal Extraction of Angiotensin II Journal of Pharmacology and Experimental Therapeutics. 307: 1001-1006. PMID 14534364 DOI: 10.1124/Jpet.103.055236  0.357
2003 Dubey RK, Zacharia LC, Gillespie DG, Imthurn B, Jackson EK. Catecholamines block the antimitogenic effect of estradiol on human glomerular mesangial cells. Hypertension. 42: 349-55. PMID 12913061 DOI: 10.1161/01.Hyp.0000088320.81260.26  0.707
2003 Zacharia LC, Dubey RK, Mi Z, Jackson EK. Methylation of 2-hydroxyestradiol in isolated organs. Hypertension. 42: 82-7. PMID 12771046 DOI: 10.1161/01.Hyp.0000074702.06466.27  0.691
2003 Cometti B, Dubey RK, Imthurn B, Jackson EK, Rosselli M. Oviduct cells express the cyclic AMP-adenosine pathway Biology of Reproduction. 69: 868-875. PMID 12724271 DOI: 10.1095/Biolreprod.103.017962  0.374
2003 Thomas NJ, Carcillo JA, Herzer WA, Mi Z, Tofovic SP, Jackson EK. Type IV phosphodiesterase inhibition improves cardiac contractility in endotoxemic rats European Journal of Pharmacology. 465: 133-139. PMID 12650842 DOI: 10.1016/S0014-2999(03)01456-0  0.325
2003 Dubey RK, Gillespie DG, Zacharia LC, Barchiesi F, Imthurn B, Jackson EK. CYP450- and COMT-derived estradiol metabolites inhibit activity of human coronary artery SMCs. Hypertension. 41: 807-13. PMID 12624000 DOI: 10.1161/01.Hyp.0000048862.28501.72  0.71
2003 Andresen BT, Linnoila JJ, Jackson EK, Romero GG. Role of EGFR transactivation in angiotensin II signaling to extracellular regulated kinase in preglomerular smooth muscle cells. Hypertension. 41: 781-6. PMID 12623996 DOI: 10.1161/01.Hyp.0000049426.61176.Df  0.336
2003 Gao L, Zhu C, Jackson EK. alpha 2-Adrenoceptors potentiate angiotensin II- and vasopressin-induced renal vasoconstriction in spontaneously hypertensive rats. The Journal of Pharmacology and Experimental Therapeutics. 305: 581-6. PMID 12606648 DOI: 10.1124/Jpet.102.047647  0.417
2003 Tofovic SP, Dubey R, Salah EM, Jackson EK. 2-Hydroxyestradiol attenuates renal disease in chronic puromycin aminonucleoside nephropathy. Journal of the American Society of Nephrology : Jasn. 13: 2737-47. PMID 12397044 DOI: 10.1097/01.Asn.0000031804.77546.F5  0.434
2003 Tofovic SP, Salah EM, Smiths G, Whalley E, Ticho B, Jackson EK. Chronic A1 and A2b adenosine receptor blockade improves diabetes and attenuates renal and cardiac histopathology in animals with the metabolic syndrome Journal of the American College of Cardiology. 41: 193. DOI: 10.1016/S0735-1097(03)81927-7  0.332
2002 Varma MR, Dixon CE, Jackson EK, Peters GW, Melick JA, Griffith RP, Vagni VA, Clark RS, Jenkins LW, Kochanek PM. Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology. Brain Research. 951: 191-201. PMID 12270497 DOI: 10.1016/S0006-8993(02)03161-X  0.335
2002 Jackson EK, Zhu C, Tofovic SP. Expression of adenosine receptors in the preglomerular microcirculation. American Journal of Physiology. Renal Physiology. 283: F41-51. PMID 12060585 DOI: 10.1152/Ajprenal.00232.2001  0.365
2002 Barchiesi F, Jackson EK, Gillespie DG, Zacharia LC, Fingerle J, Dubey RK. Methoxyestradiols mediate estradiol-induced antimitogenesis in human aortic SMCs. Hypertension. 39: 874-9. PMID 11967242 DOI: 10.1161/01.Hyp.0000013863.25970.Ba  0.713
2002 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Catecholamines block 2-hydroxyestradiol-induced antimitogenesis in mesangial cells. Hypertension. 39: 854-9. PMID 11967239 DOI: 10.1161/01.Hyp.0000014502.44988.39  0.703
2002 Tofovic SP, Kost CK, Jackson EK, Bastacky SI. Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-fa(cp)) rats. Kidney International. 61: 1433-44. PMID 11918750 DOI: 10.1046/J.1523-1755.2002.00278.X  0.31
2002 Dubey RK, Gillespie DG, Jackson EK. A(2B) adenosine receptors stimulate growth of porcine and rat arterial endothelial cells. Hypertension (Dallas, Tex. : 1979). 39: 530-5. PMID 11882603 DOI: 10.1161/Hy0202.103075  0.393
2002 Dubey RK, Gillespie DG, Keller PJ, Imthurn B, Zacharia LC, Jackson EK. Role of methoxyestradiols in the growth inhibitory effects of estradiol on human glomerular mesangial cells. Hypertension. 39: 418-24. PMID 11882583 DOI: 10.1161/Hy0202.103297  0.698
2002 Dubey RK, Gillespie DG, Zacharia LC, Rosselli M, Imthurn B, Jackson EK. Methoxyestradiols mediate the antimitogenic effects of locally applied estradiol on cardiac fibroblast growth. Hypertension. 39: 412-7. PMID 11882582 DOI: 10.1161/Hy0202.102837  0.693
2002 Tofovic SP, Zacharia L, Carcillo JA, Jackson EK. Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats. Shock (Augusta, Ga.). 16: 196-202. PMID 11531021 DOI: 10.1097/00024382-200116030-00005  0.707
2002 Jackson EK. Commentary on Liu et al Hypertension. 40: 448-450. DOI: 10.1161/01.Hyp.0000033465.65961.07  0.345
2001 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Catecholamines abrogate antimitogenic effects of 2-hydroxyestradiol on human aortic vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1745-50. PMID 11701460 DOI: 10.1161/Hq1001.097064  0.71
2001 Dubey RK, Jackson EK. Cardiovascular protective effects of 17beta-estradiol metabolites. Journal of Applied Physiology (Bethesda, Md. : 1985). 91: 1868-83. PMID 11568174 DOI: 10.1152/Jappl.2001.91.4.1868  0.332
2001 Jackson EK, Herzer WA, Kost CK, Vyas SJ. Enhanced interaction between renovascular alpha(2)-adrenoceptors and angiotensin II receptors in genetic hypertension. Hypertension (Dallas, Tex. : 1979). 38: 353-60. PMID 11566904 DOI: 10.1161/01.Hyp.38.3.353  0.37
2001 Jackson EK, Dubey RK. Role of the extracellular cAMP-adenosine pathway in renal physiology. American Journal of Physiology. Renal Physiology. 281: F597-612. PMID 11553506 DOI: 10.1152/Ajprenal.2001.281.4.F597  0.414
2001 Tofovic SP, Kusaka H, Jackson EK, Bastacky SI. Renal and metabolic effects of caffeine in obese (fa/fa(cp)), diabetic, hypertensive ZSF1 rats. Renal Failure. 23: 159-73. PMID 11417948 DOI: 10.1081/Jdi-100103488  0.328
2001 Dubey RK, Gillespie DG, Mi Z, Jackson EK. Endogenous cyclic AMP-adenosine pathway regulates cardiac fibroblast growth. Hypertension (Dallas, Tex. : 1979). 37: 1095-100. PMID 11304509 DOI: 10.1161/01.Hyp.37.4.1095  0.394
2001 Dubey RK, Gillespie DG, Zacharia LC, Mi Z, Jackson EK. A(2b) receptors mediate the antimitogenic effects of adenosine in cardiac fibroblasts. Hypertension. 37: 716-21. PMID 11230362 DOI: 10.1161/01.Hyp.37.2.716  0.708
2001 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Increased 2-methoxyestradiol production in human coronary versus aortic vascular cells. Hypertension. 37: 658-62. PMID 11230352 DOI: 10.1161/01.Hyp.37.2.658  0.683
2001 Xiao S, Gillespie DG, Baylis C, Jackson EK, Dubey RK. Effects of estradiol and its metabolites on glomerular endothelial nitric oxide synthesis and mesangial cell growth. Hypertension (Dallas, Tex. : 1979). 37: 645-50. PMID 11230350 DOI: 10.1161/01.Hyp.37.2.645  0.381
2001 Dubey RK, Jackson EK, Keller PJ, Imthurn B, Rosselli M. Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism. Hypertension. 37: 640-4. PMID 11230349 DOI: 10.1161/01.Hyp.37.2.640  0.43
2001 Andresen BT, Jackson EK, Romero GG. Angiotensin II signaling to phospholipase D in renal microvascular smooth muscle cells in SHR. Hypertension. 37: 635-9. PMID 11230348 DOI: 10.1161/01.Hyp.37.2.635  0.352
2001 Dubey RK, Jackson EK. Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms. American Journal of Physiology. Renal Physiology. 280: F365-88. PMID 11181399 DOI: 10.1152/Ajprenal.2001.280.3.F365  0.371
2001 Dubey R, Mi Z, Gillespie DG, Jackson EK. Dysregulation of extracellular adenosine levels by vascular smooth muscle cells from spontaneously hypertensive rats. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 249-54. PMID 11156861 DOI: 10.1161/01.Atv.21.2.249  0.434
2001 Tofovic SP, Zacharia LC, Carcillo JA, Jackson EK. Inhibition of cytokine release by and cardiac effects of type IV phosphodiesterase inhibition in early, profound endotoxaemia in vivo. Clinical and Experimental Pharmacology & Physiology. 27: 787-92. PMID 11022970 DOI: 10.1046/J.1440-1681.2000.03332.X  0.701
2001 Jackson EK. P1 and P2 Receptors in the Renal System Handbook of Experimental Pharmacology. 151: 33-71. DOI: 10.1007/978-3-642-56921-0_2  0.335
2000 Robertson CL, Hendrich KS, Kochanek PM, Jackson EK, Melick JA, Graham SH, Marion DW, Williams DS, Ho C. Assessment of 2-chloroadenosine treatment after experimental traumatic brain injury in the rat using arterial spin-labeled MRI: a preliminary report. Acta Neurochirurgica. Supplement. 76: 187-9. PMID 11450003 DOI: 10.1007/978-3-7091-6346-7_37  0.324
2000 Dubey RK, Gillespie DG, Zacharia LC, Rosselli M, Korzekwa KR, Fingerle J, Jackson EK. Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms. Biochemical and Biophysical Research Communications. 278: 27-33. PMID 11071850 DOI: 10.1006/Bbrc.2000.3755  0.694
2000 Jackson EK, Swamy RS, Herzer WA, Mi Z. Local and systemic effects of peritoneal lavage with high concentrations of adenosine in rats. Alimentary Pharmacology & Therapeutics. 14: 1371-80. PMID 11012485 DOI: 10.1046/J.1365-2036.2000.00830.X  0.356
2000 Dubey RK, Gillespie DG, Mi Z, Jackson EK. Cardiac fibroblasts express the cAMP-adenosine pathway. Hypertension (Dallas, Tex. : 1979). 36: 337-42. PMID 10988261 DOI: 10.1161/01.Hyp.36.3.337  0.389
2000 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Imthurn B, Keller PJ. Clinically used estrogens differentially inhibit human aortic smooth muscle cell growth and mitogen-activated protein kinase activity. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 964-72. PMID 10764660 DOI: 10.1161/01.Atv.20.4.964  0.713
2000 Kost CK, Rominski BR, Herzer WA, Jackson EK, Tofovic SP. Persistent improvement of cardiovascular risk factors in spontaneously hypertensive rats following early short-term captopril treatment. Clinical and Experimental Hypertension (New York, N.Y. : 1993). 22: 127-43. PMID 10744354 DOI: 10.1081/Ceh-100100067  0.334
2000 Dubey RK, Gillespie DG, Shue H, Jackson EK. A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 35: 267-72. PMID 10642309 DOI: 10.1161/01.Hyp.35.1.267  0.408
2000 Dubey RK, Gillespie DG, Mi Z, Rosselli M, Keller PJ, Jackson EK. Estradiol inhibits smooth muscle cell growth in part by activating the cAMP-adenosine pathway. Hypertension. 35: 262-6. PMID 10642308 DOI: 10.1161/01.Hyp.35.1.262  0.422
2000 Andresen BT, Jackson EK, Romero GG. Angiotensin II Signals to Phospholipase D in the Spontaneously Hypertensive and Wistar-Kyoto Rats by Pharmacologically Distinct Mechanisms Hypertension. 36: 722-723. DOI: 10.1161/01.Hyp.36.Suppl_1.722  0.37
2000 Xiao S, Gillespie DG, Baylis C, Jackson EK. Estradiol and Its Metabolites Differentially Induce NO Synthesis by Human Glomerular Endothelial Cells and Inhibit Glomerular Mesangial Cell Growth Hypertension. 36: 710-710. DOI: 10.1161/01.Hyp.36.Suppl_1.710-A  0.387
2000 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Increased 2-Methoxyestradiol Production in Human Coronary Artery Versus Aortic Smooth Muscle Cells: Potential Role in Mediating the Cardioprotective Effects of Estradiol Hypertension. 36: 708-708. DOI: 10.1161/01.Hyp.36.Suppl_1.708-C  0.683
2000 Dubey RK, Gillespie DG, Jackson EK. A2B Adenosine Receptors Mediate the Anti-Mitogenic Effects of Adenosine in Cardiac Fibroblasts Hypertension. 36: 708-708. DOI: 10.1161/01.Hyp.36.Suppl_1.708-B  0.358
2000 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Catecholamines Abrogate the Anti-Mitogenic Effects of 2-Hydroxy Metabolite of Estradiol on Vascular Smooth Muscle Cells by Inhibiting Catechol-O-Methyltransferase (COMT) Activity and 2-Methoxyestradiol Formation Hypertension. 36: 705-706. DOI: 10.1161/01.Hyp.36.Suppl_1.705-D  0.703
2000 Vyas SJ, Blaschak CM, Chinoy MR, Jackson EK. Molecular and Cellular Biochemistry. 212: 121-129. DOI: 10.1023/A:1007125525858  0.39
1999 Jackson EK, Herzer WA. A comparison of the natriuretic/diuretic effects of rat vs. human leptin in the rat. The American Journal of Physiology. 277: F761-5. PMID 10564240 DOI: 10.1152/Ajprenal.1999.277.5.F761  0.369
1999 Inoue T, Jackson EK. Strong antiproliferative effects of baicalein in cultured rat hepatic stellate cells. European Journal of Pharmacology. 378: 129-35. PMID 10478573 DOI: 10.1016/S0014-2999(99)00418-5  0.335
1999 Kost CK, Herzer WA, Li PJ, Jackson EK. Pertussis toxin-sensitive G-proteins and regulation of blood pressure in the spontaneously hypertensive rat. Clinical and Experimental Pharmacology and Physiology. 26: 449-455. PMID 10386237 DOI: 10.1046/J.1440-1681.1999.03058.X  0.386
1999 Tofovic SP, Kusaka H, Rominski B, Jackson EK. Caffeine increases renal renin secretion in a rat model of genetic heart failure. Journal of Cardiovascular Pharmacology. 33: 440-50. PMID 10069681 DOI: 10.1097/00005344-199903000-00015  0.395
1999 Tofovic SP, Jackson EK. Effects of long-term caffeine consumption on renal function in spontaneously hypertensive heart failure prone rats. Journal of Cardiovascular Pharmacology. 33: 360-6. PMID 10069669 DOI: 10.1097/00005344-199903000-00003  0.371
1999 Dubey RK, Tyurina YY, Tyurin VA, Gillespie DG, Branch RA, Jackson EK, Kagan VE. Estrogen and tamoxifen metabolites protect smooth muscle cell membrane phospholipids against peroxidation and inhibit cell growth. Circulation Research. 84: 229-39. PMID 9933255 DOI: 10.1161/01.Res.84.2.229  0.35
1999 Dubey RK, Gillespie DG, Jackson EK. Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 33: 190-4. PMID 9931103 DOI: 10.1161/01.Hyp.33.1.190  0.409
1999 Dubey RK, Gillespie DG, Imthurn B, Rosselli M, Jackson EK, Keller PJ. Phytoestrogens inhibit growth and MAP kinase activity in human aortic smooth muscle cells. Hypertension. 33: 177-82. PMID 9931101 DOI: 10.1161/01.Hyp.33.1.177  0.358
1999 Inoue T, Mi Z, Gillespie DG, Jackson EK. Cyclooxygenase inhibition reveals synergistic action of vasoconstrictors on mesangial cell growth. European Journal of Pharmacology. 361: 285-91. PMID 9865519 DOI: 10.1016/S0014-2999(98)00720-1  0.354
1999 Herzer WA, Thomas NJ, Carcillo JA, Tofovic SP, Jackson EK. Effects of type IV phosphodiesterase inhibition on cardiac function in the presence and absence of catecholamines. Journal of Cardiovascular Pharmacology. 32: 769-76. PMID 9821851 DOI: 10.1097/00005344-199811000-00013  0.34
1999 Thomas NJ, Carcillo JA, Herzer WA, Mi Z, Jackson EK. CARDIAC CONTRACTILITY IN ENDOTOXEMIC RATS TREATED WITH CATECHOLAMINES IS IMPROVED BY HIGH DOSE TYPE IV PHOSPHODIESTERASE (PDE4) INHIBITION WITH Ro 20-1724 Critical Care Medicine. 27: 121A. DOI: 10.1097/00003246-199901001-00326  0.31
1998 Bell M, Jackson E, Mi Z, McCombs J, Carcillo J. Low-dose theophylline increases urine output in diuretic-dependent critically ill children. Intensive Care Medicine. 24: 1099-105. PMID 9840247 DOI: 10.1007/S001340050723  0.324
1998 Kost CK, Li P, Williams DS, Jackson EK. Renal vascular responses to angiotensin II in conscious spontaneously hypertensive and normotensive rats. Journal of Cardiovascular Pharmacology. 31: 854-61. PMID 9641469 DOI: 10.1097/00005344-199806000-00008  0.395
1998 Thomas NJ, Herzer WA, Carcillo JA, Jackson EK. Effect of the type IV phosphodiesterase inhibitor Ro 20-1724 on catecholamine-induced alterations in regional vascular resistance and regional blood flow. Journal of Cardiovascular Pharmacology. 31: 840-53. PMID 9641468 DOI: 10.1097/00005344-199806000-00007  0.374
1998 Wang JJ, Hendrich KS, Jackson EK, Ildstad ST, Williams DS, Ho C. Perfusion quantitation in transplanted rat kidney by MRI with arterial spin labeling Kidney International. 53: 1783-1791. PMID 9607213 DOI: 10.1046/J.1523-1755.1998.00945.X  0.326
1998 Tofovic SP, Kusaka H, Li P, Jackson EK. Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats. Clinical and Experimental Hypertension (New York, N.Y. : 1993). 20: 329-44. PMID 9605386 DOI: 10.3109/10641969809052125  0.412
1998 Dubey RK, Gillespie DG, Jackson EK. Adenosine inhibits collagen and protein synthesis in cardiac fibroblasts: role of A2B receptors. Hypertension (Dallas, Tex. : 1979). 31: 943-8. PMID 9535419 DOI: 10.1161/01.Hyp.31.4.943  0.361
1998 Bell MJ, Kochanek PM, Carcillo JA, Mi Z, Schiding JK, Wisniewski SR, Clark RS, Dixon CE, Marion DW, Jackson E. Interstitial adenosine, inosine, and hypoxanthine are increased after experimental traumatic brain injury in the rat. Journal of Neurotrauma. 15: 163-70. PMID 9528916 DOI: 10.1089/Neu.1998.15.163  0.341
1998 Dubey RK, Gillespie DG, Jackson EK, Keller PJ. 17β-Estradiol, its metabolites, and progesterone inhibit cardiac fibroblast growth Hypertension. 31: 522-528. PMID 9453356 DOI: 10.1161/01.Hyp.31.1.522  0.354
1998 Dubey RK, Gillespie DG, Mi Z, Jackson EK. Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors. Hypertension (Dallas, Tex. : 1979). 31: 516-21. PMID 9453355 DOI: 10.1161/01.Hyp.31.1.516  0.376
1998 Dubey RK, Gillespie DG, Jackson EK. Cyclic AMP-adenosine pathway induces nitric oxide synthesis in aortic smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 31: 296-302. PMID 9453319 DOI: 10.1161/01.Hyp.31.1.296  0.408
1998 Jackson EK, Mi Z, Carcillo JA, Gillespie DG, Dubey RK. Phosphodiesterases in the rat renal vasculature. Journal of Cardiovascular Pharmacology. 30: 798-801. PMID 9436820 DOI: 10.1097/00005344-199712000-00015  0.395
1998 Thomas NJ, Carcillo JA, Herzer WA, Jackson EK. TYPE IV PHOSPHODIESTERASE (PDE) INHIBITION PROTECTS RENAL AND MESENTERIC BLOOD FLOW IN A CHRONIC MODEL OF MULTIPLE ORGAN FAILURE (MOF) TREATED WITH NOREPINEPHRINE Critical Care Medicine. 26: 79A. DOI: 10.1097/00003246-199801001-00203  0.315
1997 Mokkapatti R, Vyas SJ, Jackson EK. G protein mRNA expression in renal microvessels from spontaneously hypertensive and Wistar-Kyoto rats. American Journal of Physiology. Renal Physiology. 273: F877-F882. PMID 29586099 DOI: 10.1152/Ajprenal.1997.273.6.F877  0.34
1997 Kochanek PM, Clark RS, Obrist WD, Carcillo JA, Jackson EK, Mi Z, Wisniewski SR, Bell MJ, Marion DW. The role of adenosine during the period of delayed cerebral swelling after severe traumatic brain injury in humans. Acta Neurochirurgica. Supplement. 70: 109-11. PMID 9416294 DOI: 10.1007/978-3-7091-6837-0_34  0.312
1997 Dubey RK, Gillespie DG, Mi Z, Jackson EK. Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors. Circulation. 96: 2656-66. PMID 9355907 DOI: 10.1161/01.Cir.96.8.2656  0.318
1997 Takimoto K, Li D, Hershman KM, Li P, Jackson EK, Levitan ES. Decreased expression of Kv4.2 and novel Kv4.3 K+ channel subunit mRNAs in ventricles of renovascular hypertensive rats. Circulation Research. 81: 533-9. PMID 9314834 DOI: 10.1161/01.Res.81.4.533  0.349
1997 Jackson EK, Li P. Human leptin has natriuretic activity in the rat. The American Journal of Physiology. 272: F333-8. PMID 9087676 DOI: 10.1152/Ajprenal.1997.272.3.F333  0.356
1997 Dubey RK, Jackson EK, Rupprecht HD, Sterzel RB. Factors controlling growth and matrix production in vascular smooth muscle and glomerular mesangial cells. Current Opinion in Nephrology and Hypertension. 6: 88-105. PMID 9051360 DOI: 10.1097/00041552-199701000-00016  0.313
1996 Vitola JV, Forman MB, Holsinger JP, Kawana M, Atkinson JB, Quertermous T, Jackson EK, Murray JJ. Role of endothelin in a rabbit model of acute myocardial infarction: effects of receptor antagonists. Journal of Cardiovascular Pharmacology. 28: 774-83. PMID 8961075 DOI: 10.1097/00005344-199612000-00007  0.311
1996 Dubey RK, Mi Z, Gillespie DG, Jackson EK. Cyclic AMP-adenosine pathway inhibits vascular smooth muscle cell growth. Hypertension (Dallas, Tex. : 1979). 28: 765-71. PMID 8901821 DOI: 10.1161/01.Hyp.28.5.765  0.402
1996 Tofovic SP, Kusaka H, Pfeifer CA, Jackson EK. Central effects of caffeine on renal renin secretion and norepinephrine spillover. Journal of Cardiovascular Pharmacology. 28: 302-13. PMID 8856488 DOI: 10.1097/00005344-199608000-00018  0.4
1996 Kost CK, Herzer WA, Li P, Notoya M, Mizuhira V, Inagami T, Jackson EK. Angiotensin II-induced structural and functional alterations in spontaneously hypertensive rat kidney. The American Journal of Physiology. 270: F229-36. PMID 8769844 DOI: 10.1152/Ajprenal.1996.270.1.F229  0.386
1996 Dubey RK, Gillespie DG, Osaka K, Suzuki F, Jackson EK. Adenosine inhibits growth of rat aortic smooth muscle cells. Possible role of A2b receptor. Hypertension (Dallas, Tex. : 1979). 27: 786-93. PMID 8613241 DOI: 10.1161/01.Hyp.27.3.786  0.409
1996 Dubey RK, Gillespie DG, Mi Z, Suzuki F, Jackson EK. Smooth muscle cell-derived adenosine inhibits cell growth. Hypertension (Dallas, Tex. : 1979). 27: 766-73. PMID 8613238 DOI: 10.1161/01.Hyp.27.3.766  0.419
1995 Kost CK, Li P, Jackson EK. Blood pressure after captopril withdrawal from spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 25: 82-7. PMID 7843759 DOI: 10.1161/01.Hyp.25.1.82  0.304
1995 Dubey RK, Jackson EK, Lüscher TF. Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors. The Journal of Clinical Investigation. 96: 141-9. PMID 7615784 DOI: 10.1172/Jci118014  0.424
1995 Pfeifer CA, Suzuki F, Jackson EK. Selective A1 adenosine receptor antagonism augments beta-adrenergic-induced renin release in vivo. The American Journal of Physiology. 269: F469-79. PMID 7485531 DOI: 10.1152/Ajprenal.1995.269.4.F469  0.387
1995 Begany DP, Herzer WA, Mi Z, Carcillo JA, Jackson EK. THE ROLE OF ADENOSINE IN ENDOTOXIN INDUCED RENAL FAILURE Critical Care Medicine. 23: A214. DOI: 10.1097/00003246-199501001-00375  0.322
1994 Jackson EK. Pertussis toxin normalizes enhanced renovascular responses to angiotensin II in spontaneously hypertensive rats. Life Sciences. 54: PL445-50. PMID 8196499 DOI: 10.1016/0024-3205(94)90154-6  0.393
1994 Jackson EK, Herzer WA. Defective modulation of angiotensin II-induced renal vasoconstriction in hypertensive rats. Hypertension (Dallas, Tex. : 1979). 23: 329-36. PMID 8125559 DOI: 10.1161/01.Hyp.23.3.329  0.393
1994 Velasco CE, Turner M, Inagami T, Atkinson JB, Virmani R, Jackson EK, Murray JJ, Forman MB. Reperfusion enhances the local release of endothelin after regional myocardial ischemia American Heart Journal. 128: 441-451. PMID 8074003 DOI: 10.1016/0002-8703(94)90615-7  0.301
1994 Mi Z, Herzer WA, Zhang Y, Jackson EK. 3-isobutyl-1-methylxanthine decreases renal cortical interstitial levels of adenosine and inosine. Life Sciences. 54: 277-82. PMID 7512185 DOI: 10.1016/0024-3205(94)00846-9  0.364
1993 Kost CK, Jackson EK. Enhanced renal angiotensin II subtype 1 receptor responses in the spontaneously hypertensive rat. Hypertension (Dallas, Tex. : 1979). 21: 420-31. PMID 8458644 DOI: 10.1161/01.Hyp.21.4.420  0.383
1993 Jackson EK, Herzer WA. Angiotensin II/prostaglandin I2 interactions in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979). 22: 688-98. PMID 8225529 DOI: 10.1161/01.Hyp.22.5.688  0.386
1993 Kuan CJ, Herzer WA, Jackson EK. Cardiovascular and renal effects of blocking A1 adenosine receptors. Journal of Cardiovascular Pharmacology. 21: 822-8. PMID 7685455 DOI: 10.1097/00005344-199305000-00020  0.409
1992 Tofovic SP, Pong AS, Jackson EK. Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats. Hypertension (Dallas, Tex. : 1979). 18: 774-82. PMID 1743758 DOI: 10.1161/01.Hyp.18.6.774  0.368
1992 Norton ED, Jackson EK, Turner MB, Virmani R, Forman MB. The effects of intravenous infusions of selective adenosine A1-receptor and A2-receptor agonists on myocardial reperfusion injury. American Heart Journal. 123: 332-8. PMID 1736567 DOI: 10.1016/0002-8703(92)90643-A  0.331
1992 Jackson EK. Comments on Postma et al's "The effect of caffeine on renal vein renin concentration in patients with renal arterial disease". American Journal of Hypertension. 5: 421-2. PMID 1524771 DOI: 10.1093/Ajh/5.6.421  0.304
1992 Holycross BJ, Jackson EK. Effects of chronic treatment with caffeine on kidney responses to angiotensin II. European Journal of Pharmacology. 219: 361-7. PMID 1425965 DOI: 10.1016/0014-2999(92)90476-K  0.39
1991 Pitarys CJ, Virmani R, Vildibill HD, Jackson EK, Forman MB. Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period. Circulation. 83: 237-47. PMID 1984882 DOI: 10.1161/01.Cir.83.1.237  0.325
1991 Norton ED, Jackson EK, Virmani R, Forman MB. Effect of intravenous adenosine on myocardial reperfusion injury in a model with low myocardial collateral blood flow. American Heart Journal. 122: 1283-91. PMID 1950990 DOI: 10.1016/0002-8703(91)90567-2  0.301
1991 Kost CK, Jackson EK. Effect of angiotensin II on plasma adenosine concentrations in the rat. Journal of Cardiovascular Pharmacology. 17: 838-45. PMID 1714001 DOI: 10.1097/00005344-199105000-00021  0.367
1990 Kuan CJ, Wells JN, Jackson EK. Endogenous adenosine restrains renin release in conscious rats. Circulation Research. 66: 637-46. PMID 2407369 DOI: 10.1161/01.Res.66.3.637  0.425
1990 Kuan CJ, Branch RA, Jackson EK. Effect of an adenosine receptor antagonist on acute amphotericin B nephrotoxicity European Journal of Pharmacology. 178: 285-291. PMID 2340862 DOI: 10.1016/0014-2999(90)90107-H  0.392
1990 Jackson EK, Inagami T. Blockade of the pre- and postjunctional effects of angiotensin in vivo with a non-peptide angiotensin receptor antagonist. Life Sciences. 46: 945-53. PMID 2329920 DOI: 10.1016/0024-3205(90)90096-A  0.386
1990 Bottiglieri DF, Kost CK, Jackson EK. Angiotensin II-induced [3H]adenosine release from in situ rat lung. Journal of Cardiovascular Pharmacology. 16: 101-6. PMID 1696651 DOI: 10.1097/00005344-199007000-00014  0.326
1989 Ohnishi A, Ohnishi T, Stevenhead W, Robinson RD, Glick A, O'Day DM, Sabra R, Jackson EK, Branch RA. Sodium status influences chronic amphotericin B nephrotoxicity in rats. Antimicrobial Agents and Chemotherapy. 33: 1222-7. PMID 2802551 DOI: 10.1128/Aac.33.8.1222  0.313
1989 Deray G, Branch RA, Jackson EK. Methylxanthines augment the renin response to suprarenal-aortic constriction Naunyn-Schmiedeberg's Archives of Pharmacology. 339: 690-696. PMID 2570368 DOI: 10.1007/Bf00168663  0.412
1989 Deray G, Branch RA, Ohnishi A, Jackson EK. Adenosine inhibits renin release induced by suprarenal-aortic constriction and prostacyclin Naunyn-Schmiedeberg's Archives of Pharmacology. 339: 590-595. PMID 2570363 DOI: 10.1007/Bf00167266  0.395
1988 Bottiglieri DF, Robertson D, Jackson EK. A comparison of nucleoside transport and metabolism in hypertensive and normotensive rats. Hypertension (Dallas, Tex. : 1979). 12: 102-7. PMID 3410521 DOI: 10.1161/01.Hyp.12.2.102  0.335
1988 Jackson EK, Goto F, Uderman HD, Workman RJ, Herzer WA, FitzGerald GA, Branch RA. Effects of thromboxane synthase inhibitors on renal function. Naunyn-Schmiedeberg's Archives of Pharmacology. 337: 183-90. PMID 3285227 DOI: 10.1007/Bf00169247  0.386
1988 Oates JA, FitzGerald GA, Branch RA, Jackson EK, Knapp HR, Roberts LJ. Clinical implications of prostaglandin and thromboxane A2 formation (1). The New England Journal of Medicine. 319: 689-98. PMID 3045550 DOI: 10.1056/Nejm198809153191106  0.31
1988 Ohnishi A, Li P, Branch RA, Biaggioni IO, Jackson EK. Adenosine in renin-dependent renovascular hypertension. Hypertension (Dallas, Tex. : 1979). 12: 152-61. PMID 3044993 DOI: 10.1161/01.Hyp.12.2.152  0.398
1988 Kuan CJ, Jackson EK. Role of adenosine in noradrenergic neurotransmission American Journal of Physiology - Heart and Circulatory Physiology. 255. PMID 2841876 DOI: 10.1152/Ajpheart.1988.255.2.H386  0.359
1987 Heidemann Th. H, Jackson EK, Gerkens JF, Branch RA. Intrarenal hypertonic saline infusions in dogs with thoracic caval constriction Kidney International. 32: 488-492. PMID 3430950 DOI: 10.1038/Ki.1987.236  0.354
1987 Li P, Jackson EK. A possible explanation of genetic hypertension in the spontaneously hypertensive rat. Life Sciences. 41: 1903-8. PMID 3309518 DOI: 10.1016/0024-3205(87)90741-7  0.34
1987 Zimmerman JB, Robertson D, Jackson EK. Angiotensin II-noradrenergic interactions in renovascular hypertensive rats. The Journal of Clinical Investigation. 80: 443-57. PMID 3301900 DOI: 10.1172/Jci113092  0.361
1987 Jackson EK, Ohnishi A. Development and application of a simple microassay for adenosine in rat plasma. Hypertension (Dallas, Tex. : 1979). 10: 189-97. PMID 3301666 DOI: 10.1161/01.Hyp.10.2.189  0.366
1987 Ohnishi A, Li P, Branch RA, Holycross B, Jackson EK. Caffeine enhances the slow-pressor response to angiotensin II in rats. Evidence for a caffeine-angiotensin II interaction with the sympathetic nervous system Journal of Clinical Investigation. 80: 13-16. PMID 3110209 DOI: 10.1172/Jci113038  0.339
1987 Deray G, Branch RA, Herzer WA, Ohnishi A, Jackson EK. Adenosine inhibits β-adrenoceptor but not DBcAMP-induced renin release American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 252. PMID 3028156 DOI: 10.1152/Ajprenal.1987.252.1.F46  0.37
1987 Deray G, Branch RA, Herzer WA, Ohnishi A, Jackson EK. Effects of atrial natriuretic factor on hormone-induced renin release Hypertension. 9: 513-517. PMID 2952592 DOI: 10.1161/01.Hyp.9.5.513  0.33
1987 Jackson EK. Role of adenosine in noradrenergic neurotransmission in spontaneously hypertensive rats. The American Journal of Physiology. 253: H909-18. PMID 2821832 DOI: 10.1152/Ajpheart.1987.253.4.H909  0.397
1987 Herzer WA, Deray G, Jackson EK. Effects of Atrial Natriuretic Factor on Noradrenergic Neurotransmission In Vivo in the Rat Mesentery Journal of Cardiovascular Pharmacology. 9: 125-128. DOI: 10.1097/00005344-198701000-00020  0.357
1986 Jackson EK. Effects of thromboxane synthase inhibition on vascular responsiveness in the in vivo rat mesentery. The Journal of Clinical Investigation. 76: 2286-95. PMID 4077980 DOI: 10.1172/Jci112238  0.351
1986 Ohnishi A, Biaggioni I, Deray G, Branch RA, Jackson EK. Hemodynamic effects of adenosine in conscious hypertensive And Normotensive Rats Hypertension. 8: 391-398. PMID 3699881 DOI: 10.1161/01.Hyp.8.5.391  0.354
1986 Ohnishi A, Branch RA, Jackson K, Hamilton R, Biaggioni I, Deray G, Jackson EK. Chronic caffeine administration exacerbates renovascular, but not genetic, hypertension in rats. The Journal of Clinical Investigation. 78: 1045-50. PMID 3020089 DOI: 10.1172/Jci112659  0.345
1986 Fitzgerald DJ, Doran J, Jackson E, FitzGerald GA. Coronary vascular occlusion mediated via thromboxane A2-prostaglandin endoperoxide receptor activation in vivo. The Journal of Clinical Investigation. 77: 496-502. PMID 3003161 DOI: 10.1172/Jci112329  0.36
1986 Nakamaru M, Jackson EK, Inagami T. Beta-adrenoceptor-mediated release of angiotensin II from mesenteric arteries. The American Journal of Physiology. 250: H144-8. PMID 3002196 DOI: 10.1152/Ajpheart.1986.250.1.H144  0.345
1986 Nakamaru M, Jackson EK, Inagami T. Role of vascular angiotensin II released by beta-adrenergic stimulation in rats. Journal of Cardiovascular Pharmacology. 8: S1-5. PMID 2438481 DOI: 10.1097/00005344-198600101-00002  0.372
1986 Deray G, Branch RA, Herzer WH, Jackson EK. Adenosine Inhibits Norepinephrine but not Dibutyryl Cyclic AMP-Induced Renin Release Journal of Hypertension. 4: 660-661. DOI: 10.1097/00004872-198610000-00071  0.33
1985 Heidemann HT, Gerkens JF, Jackson EK, Branch RA. Attenuation of cisplatinum-induced nephrotoxicity in the rat by high salt diet, furosemide and acetazolamide Naunyn-Schmiedeberg's Archives of Pharmacology. 329: 201-205. PMID 4040218 DOI: 10.1007/Bf00501213  0.347
1985 Heidemann HT, Jackson EK, Gerkens JF, Workman RJ, Branch RA. Unilaterally nephrectomized rat with aortic ligation: a uremic model of severe hypertension. Clinical and Experimental Hypertension. Part a, Theory and Practice. 7: 1109-20. PMID 3899421 DOI: 10.3109/10641968509073578  0.372
1984 Jackson EK, Uderman HD, Herzer WA, Branch RA. Attenuation of noradrenergic neurotransmission by the thromboxane synthetase inhibitor, UK 38,485 Life Sciences. 35: 221-228. PMID 6330486 DOI: 10.1016/0024-3205(84)90143-7  0.364
1984 Uderman HD, Jackson EK, Puett D, Workman RJ. Thromboxane synthetase inhibitor UK38,485 lowers blood pressure in the adult spontaneously hypertensive rat. Journal of Cardiovascular Pharmacology. 6: 969-72. PMID 6209508 DOI: 10.1097/00005344-198409000-00035  0.321
1983 Uderman HD, Workman RJ, Jackson EK. Attenuation of the development of hypertension in spontaneously hypertensive rats by the thromboxane synthetase inhibitor, 4'-(imidazol-1-yl) acetophenone. Prostaglandins. 24: 237-44. PMID 6897296 DOI: 10.1016/0090-6980(82)90149-6  0.33
1983 Heidemann HT, Gerkens JF, Jackson EK, Branch RA. Effect of aminophylline on renal vasoconstriction produced by amphotericin B in the rat Naunyn-Schmiedeberg's Archives of Pharmacology. 324: 148-152. PMID 6646242 DOI: 10.1007/Bf00497021  0.358
1983 Heidemann HT, Gerkens JF, Spickard WA, Jackson EK, Branch RA. Amphotericin B nephrotoxicity in humans decreased by salt repletion. The American Journal of Medicine. 75: 476-81. PMID 6614033 DOI: 10.1016/0002-9343(83)90353-4  0.313
1982 Jackson EK, Heidemann Th. H, Branch RA, Gerkens JF. Low dose intrarenal infusions of PGE2, PGI2, and 6-keto-PGE1 vasodilate the in vivo rat kidney Circulation Research. 51: 67-72. PMID 7044603 DOI: 10.1161/01.Res.51.1.67  0.357
1982 Tsunoda S, Jackson EK, Branch RA, Gerkens JF. Comparison of the pulmonary, hepatic and renal extraction of PGI2 and 6-KETO-PGE1 European Journal of Pharmacology. 77: 147-151. PMID 7037431 DOI: 10.1016/0014-2999(82)90010-3  0.316
1981 Jackson EK, Oates JA, Branch RA. Indomethacin decreases arterial blood pressure and plasma renin activity in rats with aortic ligation Circulation Research. 49: 180-185. PMID 7016365 DOI: 10.1161/01.Res.49.1.180  0.337
1981 Jackson EK, Campbell WB. A possible antihypertensive mechanism of propranolol: antagonism of angiotensin II enhancement of sympathetic nerve transmission through prostaglandins. Hypertension (Dallas, Tex. : 1979). 3: 23-33. PMID 6259059 DOI: 10.1161/01.Hyp.3.1.23  0.38
1981 Jackson EK, Campbell WB. The in situ blood perfused rat mesentery; a model for assessing modulation of adrenergic neurotransmission. European Journal of Pharmacology. 66: 217-24. PMID 6254783 DOI: 10.1016/0014-2999(80)90145-4  0.341
1980 Jackson EK, Campbell WB. Inhibition of angiotensin II potentiation of sympathetic nerve activity by beta-adrenergic antagonists. Hypertension (Dallas, Tex. : 1979). 2: 90-6. PMID 6102965 DOI: 10.1161/01.Hyp.2.1.90  0.34
1980 Campbell WB, Jackson EK, Graham RM. Saralasin-induced renin release: its blockade by prostaglandin synthesis inhibitors in the conscious rat. Hypertension (Dallas, Tex. : 1979). 1: 637-42. PMID 120320 DOI: 10.1161/01.Hyp.1.6.637  0.41
1979 Campbell WB, Jackson EK. Modulation of adrenergic transmission by angiotensins in the perfused rat mesentery. The American Journal of Physiology. 236: H211-7. PMID 217278 DOI: 10.1152/Ajpheart.1979.236.2.H211  0.343
1979 Campbell WB, Graham RM, Jackson EK. Role of renal prostaglandins in sympathetically mediated renin relase in the rat. The Journal of Clinical Investigation. 64: 448-56. PMID 37256 DOI: 10.1172/Jci109482  0.414
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