Patrick L. Iversen - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Pharmacology, Molecular Biology, Cell Biology

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E. Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies. Antimicrobial Agents and Chemotherapy. 58: 6639-47. PMID 25155593 DOI: 10.1128/AAC.03442-14  0.32
2014 Punj S, Kopparapu P, Jang HS, Phillips JL, Pennington J, Rohlman D, O'Donnell E, Iversen PL, Kolluri SK, Kerkvliet NI. Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease. Plos One. 9: e88726. PMID 24586378 DOI: 10.1371/journal.pone.0088726  0.32
2014 Mourich DV, Oda SK, Schnell FJ, Crumley SL, Hauck LL, Moentenich CA, Marshall NB, Hinrichs DJ, Iversen PL. Alternative splice forms of CTLA-4 induced by antisense mediated splice-switching influences autoimmune diabetes susceptibility in NOD mice. Nucleic Acid Therapeutics. 24: 114-26. PMID 24494586 DOI: 10.1089/nat.2013.0449  0.32
2012 Iversen PL, Warren TK, Wells JB, Garza NL, Mourich DV, Welch LS, Panchal RG, Bavari S. Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections. Viruses. 4: 2806-30. PMID 23202506 DOI: 10.3390/v4112806  0.32
2012 Puckett SE, Reese KA, Mitev GM, Mullen V, Johnson RC, Pomraning KR, Mellbye BL, Tilley LD, Iversen PL, Freitag M, Geller BL. Bacterial resistance to antisense peptide phosphorodiamidate morpholino oligomers. Antimicrobial Agents and Chemotherapy. 56: 6147-53. PMID 22985881 DOI: 10.1128/AAC.00850-12  0.32
2011 Du L, Kayali R, Bertoni C, Fike F, Hu H, Iversen PL, Gatti RA. Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum. Human Molecular Genetics. 20: 3151-60. PMID 21576124 DOI: 10.1093/hmg/ddr217  0.32
2010 Warren TK, Warfield KL, Wells J, Swenson DL, Donner KS, Van Tongeren SA, Garza NL, Dong L, Mourich DV, Crumley S, Nichols DK, Iversen PL, Bavari S. Advanced antisense therapies for postexposure protection against lethal filovirus infections. Nature Medicine. 16: 991-4. PMID 20729866 DOI: 10.1038/nm.2202  0.32
2010 Greenberg DE, Marshall-Batty KR, Brinster LR, Zarember KA, Shaw PA, Mellbye BL, Iversen PL, Holland SM, Geller BL. Antisense phosphorodiamidate morpholino oligomers targeted to an essential gene inhibit Burkholderia cepacia complex. The Journal of Infectious Diseases. 201: 1822-30. PMID 20438352 DOI: 10.1086/652807  0.32
2010 Mellbye BL, Weller DD, Hassinger JN, Reeves MD, Lovejoy CE, Iversen PL, Geller BL. Cationic phosphorodiamidate morpholino oligomers efficiently prevent growth of Escherichia coli in vitro and in vivo. The Journal of Antimicrobial Chemotherapy. 65: 98-106. PMID 19884121 DOI: 10.1093/jac/dkp392  0.32
2009 Iversen PL, Aird KM, Wu R, Morse MM, Devi GR. Cellular uptake of neutral phosphorodiamidate morpholino oligomers. Current Pharmaceutical Biotechnology. 10: 579-88. PMID 19619124 DOI: 10.2174/138920109789069279  0.32
2009 Swenson DL, Warfield KL, Warren TK, Lovejoy C, Hassinger JN, Ruthel G, Blouch RE, Moulton HM, Weller DD, Iversen PL, Bavari S. Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection. Antimicrobial Agents and Chemotherapy. 53: 2089-99. PMID 19223614 DOI: 10.1128/AAC.00936-08  0.32
2008 Jearawiriyapaisarn N, Moulton HM, Buckley B, Roberts J, Sazani P, Fucharoen S, Iversen PL, Kole R. Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1624-9. PMID 18545222 DOI: 10.1038/mt.2008.120  0.32
2008 Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R. A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrobial Agents and Chemotherapy. 52: 1970-81. PMID 18347107 DOI: 10.1128/AAC.00011-08  0.32
2008 Gabriel G, Nordmann A, Stein DA, Iversen PL, Klenk HD. Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus. The Journal of General Virology. 89: 939-48. PMID 18343835 DOI: 10.1099/vir.0.83449-0  0.32
2008 Smith AW, Iversen PL, O'Hanley PD, Skilling DE, Christensen JR, Weaver SS, Longley K, Stone MA, Poet SE, Matson DO. Virus-specific antiviral treatment for controlling severe and fatal outbreaks of feline calicivirus infection. American Journal of Veterinary Research. 69: 23-32. PMID 18167083 DOI: 10.2460/ajvr.69.1.23  0.32
2008 Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Research. 77: 95-107. PMID 17959259 DOI: 10.1016/j.antiviral.2007.09.002  0.32
2007 Silvestri LS, Ruthel G, Kallstrom G, Warfield KL, Swenson DL, Nelle T, Iversen PL, Bavari S, Aman MJ. Involvement of vacuolar protein sorting pathway in Ebola virus release independent of TSG101 interaction. The Journal of Infectious Diseases. 196: S264-70. PMID 17940959 DOI: 10.1086/520610  0.32
2007 Adams AM, Harding PL, Iversen PL, Coleman C, Fletcher S, Wilton SD. Antisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistries. Bmc Molecular Biology. 8: 57. PMID 17601349 DOI: 10.1186/1471-2199-8-57  0.32
2006 Yuan J, Stein DA, Lim T, Qiu D, Coughlin S, Liu Z, Wang Y, Blouch R, Moulton HM, Iversen PL, Yang D. Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site. Journal of Virology. 80: 11510-9. PMID 16987987 DOI: 10.1128/JVI.00900-06  0.32
2006 Tilley LD, Hine OS, Kellogg JA, Hassinger JN, Weller DD, Iversen PL, Geller BL. Gene-specific effects of antisense phosphorodiamidate morpholino oligomer-peptide conjugates on Escherichia coli and Salmonella enterica serovar typhimurium in pure culture and in tissue culture. Antimicrobial Agents and Chemotherapy. 50: 2789-96. PMID 16870773 DOI: 10.1128/AAC.01286-05  0.32
2006 Enterlein S, Warfield KL, Swenson DL, Stein DA, Smith JL, Gamble CS, Kroeker AD, Iversen PL, Bavari S, Mühlberger E. VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice. Antimicrobial Agents and Chemotherapy. 50: 984-93. PMID 16495261 DOI: 10.1128/AAC.50.3.984-993.2006  0.32
2006 Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S. Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers. Plos Pathogens. 2: e1. PMID 16415982 DOI: 10.1371/journal.ppat.0020001  0.32
2006 Holden KL, Stein DA, Pierson TC, Ahmed AA, Clyde K, Iversen PL, Harris E. Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. Virology. 344: 439-52. PMID 16214197 DOI: 10.1016/j.virol.2005.08.034  0.32
2005 Neuman BW, Stein DA, Kroeker AD, Churchill MJ, Kim AM, Kuhn P, Dawson P, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ. Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers. Journal of Virology. 79: 9665-76. PMID 16014928 DOI: 10.1128/JVI.79.15.9665-9676.2005  0.32
2005 Kinney RM, Huang CY, Rose BC, Kroeker AD, Dreher TW, Iversen PL, Stein DA. Inhibition of dengue virus serotypes 1 to 4 in vero cell cultures with morpholino oligomers. Journal of Virology. 79: 5116-28. PMID 15795296 DOI: 10.1128/JVI.79.8.5116-5128.2005  0.32
2004 Pannier AK, Arora V, Iversen PL, Brand RM. Transdermal delivery of phosphorodiamidate Morpholino oligomers across hairless mouse skin. International Journal of Pharmaceutics. 275: 217-26. PMID 15081152 DOI: 10.1016/j.ijpharm.2004.02.001  0.32
2003 Geller BL, Deere JD, Stein DA, Kroeker AD, Moulton HM, Iversen PL. Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers Antimicrobial Agents and Chemotherapy. 47: 3233-3239. PMID 14506035 DOI: 10.1128/AAC.47.10.3233-3239.2003  0.32
2003 Knapp DC, Mata JE, Reddy MT, Devi GR, Iversen PL. Resistance to chemotherapeutic drugs overcome by c-Myc inhibition in a Lewis lung carcinoma murine model. Anti-Cancer Drugs. 14: 39-47. PMID 12544257  0.6
2002 Ricker JL, Mata JE, Iversen PL, Gattone VH. c-myc antisense oligonucleotide treatment ameliorates murine ARPKD. Kidney International. 61: S125-31. PMID 11841626 DOI: 10.1046/j.1523-1755.2002.0610s1125.x  0.32
2000 Mata JE, Bishop MR, Tarantolo SR, Angel CR, Swanson SA, Iversen PL. Evidence of enhanced iron excretion during systemic phosphorothioate oligodeoxynucleotide treatment. Journal of Toxicology. Clinical Toxicology. 38: 383-7. PMID 10930054  0.6
2000 Mata JE, Jackson JD, Joshi SS, Tracewell WG, Pirruccello SJ, Murphy BJ, Bishop MR, Iversen PL. Pharmacokinetics and in vivo effects of a six-base phosphorothioate oligodeoxynucleotide with anticancer and hematopoietic activities in swine. Journal of Hematotherapy & Stem Cell Research. 9: 205-14. PMID 10813533  0.6
1999 Iversen PL, Cornish KG, Iversen LJ, Mata JE, Bylund DB. Bolus intravenous injection of phosphorothioate oligonucleotides causes hypotension by acting as alpha(1)-adrenergic receptor antagonists. Toxicology and Applied Pharmacology. 160: 289-96. PMID 10544063 DOI: 10.1006/taap.1999.8771  0.6
1999 Page TJ, Mata JE, Bridge JA, Siebler JC, Neff JR, Iversen PL. The cytotoxic effects of single-stranded telomere mimics on OMA-BL1 cells. Experimental Cell Research. 252: 41-9. PMID 10502398 DOI: 10.1006/excr.1999.4613  0.32
1997 Bishop MR, Jackson JD, Tarantolo SR, O'Kane-Murphy B, Iversen PL, Bayever E, Joshi SM, Sharp JG, Pierson JL, Warkentin PI, Armitage JO, Kessinger A. Ex vivo treatment of bone marrow with phosphorothioate oligonucleotide OL(1)p53 for autologous transplantation in acute myelogenous leukemia and myelodysplastic syndrome. Journal of Hematotherapy. 6: 441-6. PMID 9368180  0.32
1997 Takeda A, Hisada H, Okada S, Mata JE, Ebadi M, Iversen PL. Tumor cell growth is inhibited by suppressing metallothionein-I synthesis. Cancer Letters. 116: 145-9. PMID 9215857  0.6
1997 Mata JE, Joshi SS, Palen B, Pirruccello SJ, Jackson JD, Elias N, Page TJ, Medlin KL, Iversen PL. A hexameric phosphorothioate oligonucleotide telomerase inhibitor arrests growth of Burkitt's lymphoma cells in vitro and in vivo. Toxicology and Applied Pharmacology. 144: 189-97. PMID 9169084 DOI: 10.1006/taap.1997.8103  0.32
1995 Wang M, Mata J, Price CE, Iversen PL, Godfrey M. Prenatal and presymptomatic diagnosis of the Marfan syndrome using fluorescence PCR and an automated sequencer. Prenatal Diagnosis. 15: 499-507. PMID 7659684 DOI: 10.1002/pd.1970150602  0.32
1995 Ebadi M, Iversen PL, Hao R, Cerutis DR, Rojas P, Happe HK, Murrin LC, Pfeiffer RF. Expression and regulation of brain metallothionein. Neurochemistry International. 27: 1-22. PMID 7655341 DOI: 10.1016/0197-0186(94)00164-P  0.32
1995 Srinivasan SK, Tewary HK, Iversen PL. Characterization of binding sites, extent of binding, and drug interactions of oligonucleotides with albumin. Antisense Research and Development. 5: 131-9. PMID 7580117 DOI: 10.1089/ARD.1995.5.131  0.32
1994 Takeda A, Norris JS, Iversen PL, Ebadi M. Antisense oligonucleotide of c-myc discriminates between zinc- and dexamethasone-induced synthesis of metallothionein. Pharmacology. 48: 119-26. PMID 8134403 DOI: 10.1159/000139170  0.6
1994 Iversen PL, Mata J, Tracewell WG, Zon G. Pharmacokinetics of an antisense phosphorothioate oligodeoxynucleotide against rev from human immunodeficiency virus type 1 in the adult male rat following single injections and continuous infusion Antisense Research and Development. 4: 43-52. PMID 8061515 DOI: 10.1089/ARD.1994.4.43  0.32
1994 Pirruccello SJ, Perry GA, Bock PJ, Lang MS, Noel SM, Zon G, Iversen PL. HIV-1 rev antisense phosphorothioate oligonucleotide binding to human mononuclear cells is cell type specific and inducible. Antisense Research and Development. 4: 285-9. PMID 7734943 DOI: 10.1089/ARD.1994.4.285  0.32
1993 Bayever E, Iversen PL, Bishop MR, Sharp JG, Tewary HK, Arneson MA, Pirruccello SJ, Ruddon RW, Kessinger A, Zon G. Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a phase I trial. Antisense Research and Development. 3: 383-90. PMID 8155979 DOI: 10.1089/ARD.1993.3.383  0.32
1992 Iversen PL, Crouse D, Zon G, Perry G. Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible Antisense Research and Development. 2: 223-233. PMID 1490073 DOI: 10.1089/ARD.1992.2.223  0.32
1992 Iversen PL, Mata JE, Ebadi M. Synthetic antisense oligonucleotide probes the essentiality of metallothionein gene. Biological Signals. 1: 293-9. PMID 1307930  0.6
1990 Paliwal VK, Iversen PL, Ebadi M. Regulation of zinc metallothionein II mRNA level in rat brain. Neurochemistry International. 17: 441-7. PMID 20504644 DOI: 10.1016/0197-0186(90)90026-P  0.6
1985 Hines RN, Levy JB, Conrad RD, Iversen PL, Shen ML, Renli AM, Bresnick E. Gene structure and nucleotide sequence for rat cytochrome P-450c Archives of Biochemistry and Biophysics. 237: 465-476. PMID 3838427 DOI: 10.1016/0003-9861(85)90300-5  0.32
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