| Year |
Citation |
Score |
| 2018 |
Annalora AJ, Jozic M, Marcus CB, Iversen PL. Alternative splicing of the vitamin D receptor modulates target gene expression and promotes ligand-independent functions. Toxicology and Applied Pharmacology. PMID 30552932 DOI: 10.1016/J.Taap.2018.12.009 |
0.302 |
|
| 2018 |
Annalora AJ, O'Neil S, Bushman JD, Summerton JE, Marcus CB, Iversen PL. A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors. Oncotarget. 9: 30568-30586. PMID 30093970 DOI: 10.18632/Oncotarget.25736 |
0.335 |
|
| 2017 |
Annalora AJ, Marcus CB, Iversen PL. Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28188297 DOI: 10.1124/Dmd.116.073254 |
0.301 |
|
| 2015 |
Warren TK, Whitehouse CA, Wells J, Welch L, Heald AE, Charleston JS, Sazani P, Reid SP, Iversen PL, Bavari S. A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection. Mbio. 6. PMID 25670780 DOI: 10.1128/Mbio.02344-14 |
0.314 |
|
| 2014 |
Heald AE, Iversen PL, Saoud JB, Sazani P, Charleston JS, Axtelle T, Wong M, Smith WB, Vutikullird A, Kaye E. Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies. Antimicrobial Agents and Chemotherapy. 58: 6639-47. PMID 25155593 DOI: 10.1128/Aac.03442-14 |
0.319 |
|
| 2013 |
Geller BL, Marshall-Batty K, Schnell FJ, McKnight MM, Iversen PL, Greenberg DE. Gene-silencing antisense oligomers inhibit acinetobacter growth in vitro and in vivo. The Journal of Infectious Diseases. 208: 1553-60. PMID 24130069 DOI: 10.1093/Infdis/Jit460 |
0.332 |
|
| 2013 |
Schnell FJ, Crumley SL, Mourich DV, Iversen PL. Development of novel bioanalytical methods to determine the effective concentrations of phosphorodiamidate morpholino oligomers in tissues and cells. Bioresearch Open Access. 2: 61-6. PMID 23515175 DOI: 10.1089/Biores.2012.0276 |
0.336 |
|
| 2012 |
Iversen PL, Warren TK, Wells JB, Garza NL, Mourich DV, Welch LS, Panchal RG, Bavari S. Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections. Viruses. 4: 2806-30. PMID 23202506 DOI: 10.3390/V4112806 |
0.323 |
|
| 2012 |
Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S. Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis. Nucleic Acid Therapeutics. 22: 316-22. PMID 22978365 DOI: 10.1089/Nat.2012.0362 |
0.34 |
|
| 2012 |
Ma W, Lin Y, Xuan W, Iversen PL, Smith LJ, Benchimol S. Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs. Oncogene. 31: 1024-33. PMID 21765469 DOI: 10.1038/Onc.2011.300 |
0.337 |
|
| 2012 |
Joshi S, Wu A, Verbik D, Algarra S, Bishop M, Pirruccello S, Iversen P, Jackson J, Kessinger M, Sharp J. Oligonucleotides complementary to c-myb messenger RNA inhibit growth and induce apoptosis in human Burkitt lymphoma cells. International Journal of Oncology. 8: 815-20. PMID 21544432 DOI: 10.3892/Ijo.8.4.815 |
0.359 |
|
| 2011 |
Du L, Kayali R, Bertoni C, Fike F, Hu H, Iversen PL, Gatti RA. Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum. Human Molecular Genetics. 20: 3151-60. PMID 21576124 DOI: 10.1093/Hmg/Ddr217 |
0.338 |
|
| 2009 |
Moerdyk-Schauwecker M, Stein DA, Eide K, Blouch RE, Bildfell R, Iversen P, Jin L. Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27. Antiviral Research. 84: 131-41. PMID 19665486 DOI: 10.1016/J.Antiviral.2009.07.020 |
0.331 |
|
| 2009 |
Iversen PL, Aird KM, Wu R, Morse MM, Devi GR. Cellular uptake of neutral phosphorodiamidate morpholino oligomers. Current Pharmaceutical Biotechnology. 10: 579-88. PMID 19619124 DOI: 10.2174/138920109789069279 |
0.349 |
|
| 2009 |
Mitev GM, Mellbye BL, Iversen PL, Geller BL. Inhibition of intracellular growth of Salmonella enterica serovar Typhimurium in tissue culture by antisense peptide-phosphorodiamidate morpholino oligomer. Antimicrobial Agents and Chemotherapy. 53: 3700-4. PMID 19581453 DOI: 10.1128/Aac.00099-09 |
0.322 |
|
| 2009 |
Mourich DV, Jendrzejewski JL, Marshall NB, Hinrichs DJ, Iversen PL, Brand RM. Antisense targeting of cFLIP sensitizes activated T cells to undergo apoptosis and desensitizes responses to contact dermatitis. The Journal of Investigative Dermatology. 129: 1945-53. PMID 19225545 DOI: 10.1038/Jid.2009.16 |
0.332 |
|
| 2009 |
Swenson DL, Warfield KL, Warren TK, Lovejoy C, Hassinger JN, Ruthel G, Blouch RE, Moulton HM, Weller DD, Iversen PL, Bavari S. Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection. Antimicrobial Agents and Chemotherapy. 53: 2089-99. PMID 19223614 DOI: 10.1128/Aac.00936-08 |
0.35 |
|
| 2009 |
Sleeman K, Stein DA, Tamin A, Reddish M, Iversen PL, Rota PA. Inhibition of measles virus infections in cell cultures by peptide-conjugated morpholino oligomers. Virus Research. 140: 49-56. PMID 19059443 DOI: 10.1016/J.Virusres.2008.10.018 |
0.373 |
|
| 2009 |
Mellbye BL, Puckett SE, Tilley LD, Iversen PL, Geller BL. Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo. Antimicrobial Agents and Chemotherapy. 53: 525-30. PMID 19015356 DOI: 10.1128/Aac.00917-08 |
0.318 |
|
| 2008 |
Abes R, Moulton HM, Clair P, Yang ST, Abes S, Melikov K, Prevot P, Youngblood DS, Iversen PL, Chernomordik LV, Lebleu B. Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies. Nucleic Acids Research. 36: 6343-54. PMID 18796528 DOI: 10.1093/Nar/Gkn541 |
0.316 |
|
| 2008 |
Bok K, Cavanaugh VJ, Matson DO, González-Molleda L, Chang KO, Zintz C, Smith AW, Iversen P, Green KY, Campbell AE. Inhibition of norovirus replication by morpholino oligomers targeting the 5'-end of the genome. Virology. 380: 328-37. PMID 18783811 DOI: 10.1016/J.Virol.2008.08.007 |
0.347 |
|
| 2008 |
Stein DA, Huang CY, Silengo S, Amantana A, Crumley S, Blouch RE, Iversen PL, Kinney RM. Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus. The Journal of Antimicrobial Chemotherapy. 62: 555-65. PMID 18567576 DOI: 10.1093/Jac/Dkn221 |
0.309 |
|
| 2008 |
Jearawiriyapaisarn N, Moulton HM, Buckley B, Roberts J, Sazani P, Fucharoen S, Iversen PL, Kole R. Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1624-9. PMID 18545222 DOI: 10.1038/Mt.2008.120 |
0.32 |
|
| 2008 |
Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA. Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers. Virology. 376: 357-70. PMID 18468653 DOI: 10.1016/J.Virol.2008.03.032 |
0.347 |
|
| 2008 |
Lai SH, Stein DA, Guerrero-Plata A, Liao SL, Ivanciuc T, Hong C, Iversen PL, Casola A, Garofalo RP. Inhibition of respiratory syncytial virus infections with morpholino oligomers in cell cultures and in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1120-8. PMID 18443602 DOI: 10.1038/Mt.2008.81 |
0.361 |
|
| 2008 |
Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M. Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers. Archives of Virology. 153: 929-37. PMID 18369525 DOI: 10.1007/S00705-008-0067-0 |
0.318 |
|
| 2008 |
Zhang YJ, Bonaparte RS, Patel D, Stein DA, Iversen PL. Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus. Molecular Cancer Therapeutics. 7: 712-20. PMID 18347156 DOI: 10.1158/1535-7163.Mct-07-2036 |
0.376 |
|
| 2008 |
Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R. A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrobial Agents and Chemotherapy. 52: 1970-81. PMID 18347107 DOI: 10.1128/Aac.00011-08 |
0.383 |
|
| 2008 |
Gabriel G, Nordmann A, Stein DA, Iversen PL, Klenk HD. Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus. The Journal of General Virology. 89: 939-48. PMID 18343835 DOI: 10.1099/Vir.0.83449-0 |
0.347 |
|
| 2008 |
Abes R, Arzumanov A, Moulton H, Abes S, Ivanova G, Gait MJ, Iversen P, Lebleu B. Arginine‐rich cell penetrating peptides: Design, structure–activity, and applications to alter pre‐mRNA splicing by steric‐block oligonucleotides Journal of Peptide Science. 14: 455-460. PMID 18236382 DOI: 10.1002/Psc.979 |
0.317 |
|
| 2008 |
Lebleu B, Moulton HM, Abes R, Ivanova GD, Abes S, Stein DA, Iversen PL, Arzumanov AA, Gait MJ. Cell penetrating peptide conjugates of steric block oligonucleotides. Advanced Drug Delivery Reviews. 60: 517-29. PMID 18037527 DOI: 10.1016/J.Addr.2007.09.002 |
0.303 |
|
| 2008 |
Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Research. 77: 95-107. PMID 17959259 DOI: 10.1016/J.Antiviral.2007.09.002 |
0.357 |
|
| 2007 |
Vagnozzi A, Stein DA, Iversen PL, Rieder E. Inhibition of foot-and-mouth disease virus infections in cell cultures with antisense morpholino oligomers. Journal of Virology. 81: 11669-80. PMID 17728223 DOI: 10.1128/Jvi.00557-07 |
0.351 |
|
| 2007 |
Marshall NB, Oda SK, London CA, Moulton HM, Iversen PL, Kerkvliet NI, Mourich DV. Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing. Journal of Immunological Methods. 325: 114-26. PMID 17673254 DOI: 10.1016/J.Jim.2007.06.009 |
0.366 |
|
| 2007 |
Wu RP, Youngblood DS, Hassinger JN, Lovejoy CE, Nelson MH, Iversen PL, Moulton HM. Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity. Nucleic Acids Research. 35: 5182-91. PMID 17670797 DOI: 10.1093/Nar/Gkm478 |
0.309 |
|
| 2007 |
Moulton HM, Fletcher S, Neuman BW, McClorey G, Stein DA, Abes S, Wilton SD, Buchmeier MJ, Lebleu B, Iversen PL. Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo. Biochemical Society Transactions. 35: 826-8. PMID 17635157 DOI: 10.1042/Bst0350826 |
0.301 |
|
| 2007 |
Adams AM, Harding PL, Iversen PL, Coleman C, Fletcher S, Wilton SD. Antisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistries. Bmc Molecular Biology. 8: 57. PMID 17601349 DOI: 10.1186/1471-2199-8-57 |
0.311 |
|
| 2007 |
Amantana A, Moulton HM, Cate ML, Reddy MT, Whitehead T, Hassinger JN, Youngblood DS, Iversen PL. Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate. Bioconjugate Chemistry. 18: 1325-31. PMID 17583927 DOI: 10.1021/Bc070060V |
0.333 |
|
| 2007 |
Fletcher S, Honeyman K, Fall AM, Harding PL, Johnsen RD, Steinhaus JP, Moulton HM, Iversen PL, Wilton SD. Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1587-92. PMID 17579573 DOI: 10.1038/Sj.Mt.6300245 |
0.308 |
|
| 2007 |
Deas TS, Bennett CJ, Jones SA, Tilgner M, Ren P, Behr MJ, Stein DA, Iversen PL, Kramer LD, Bernard KA, Shi PY. In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus. Antimicrobial Agents and Chemotherapy. 51: 2470-82. PMID 17485503 DOI: 10.1128/Aac.00069-07 |
0.35 |
|
| 2007 |
Burrer R, Neuman BW, Ting JP, Stein DA, Moulton HM, Iversen PL, Kuhn P, Buchmeier MJ. Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models. Journal of Virology. 81: 5637-48. PMID 17344287 DOI: 10.1128/Jvi.02360-06 |
0.351 |
|
| 2007 |
Abes S, Moulton H, Turner J, Clair P, Richard JP, Iversen P, Gait MJ, Lebleu B. Peptide-based delivery of nucleic acids: design, mechanism of uptake and applications to splice-correcting oligonucleotides. Biochemical Society Transactions. 35: 53-55. PMID 17233600 DOI: 10.1042/Bst0350053 |
0.305 |
|
| 2007 |
Zhang YJ, Wang KY, Stein DA, Patel D, Watkins R, Moulton HM, Iversen PL, Matson DO. Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers. Antiviral Research. 73: 12-23. PMID 16842866 DOI: 10.1016/J.Antiviral.2006.05.017 |
0.371 |
|
| 2006 |
Yuan J, Stein DA, Lim T, Qiu D, Coughlin S, Liu Z, Wang Y, Blouch R, Moulton HM, Iversen PL, Yang D. Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site. Journal of Virology. 80: 11510-9. PMID 16987987 DOI: 10.1128/Jvi.00900-06 |
0.378 |
|
| 2006 |
Ge Q, Pastey M, Kobasa D, Puthavathana P, Lupfer C, Bestwick RK, Iversen PL, Chen J, Stein DA. Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers. Antimicrobial Agents and Chemotherapy. 50: 3724-33. PMID 16966399 DOI: 10.1128/Aac.00644-06 |
0.364 |
|
| 2006 |
Tilley LD, Hine OS, Kellogg JA, Hassinger JN, Weller DD, Iversen PL, Geller BL. Gene-specific effects of antisense phosphorodiamidate morpholino oligomer-peptide conjugates on Escherichia coli and Salmonella enterica serovar typhimurium in pure culture and in tissue culture. Antimicrobial Agents and Chemotherapy. 50: 2789-96. PMID 16870773 DOI: 10.1128/Aac.01286-05 |
0.317 |
|
| 2006 |
Zhang YJ, Stein DA, Fan SM, Wang KY, Kroeker AD, Meng XJ, Iversen PL, Matson DO. Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers. Veterinary Microbiology. 117: 117-29. PMID 16839712 DOI: 10.1016/J.Vetmic.2006.06.006 |
0.382 |
|
| 2006 |
Mcclorey G, Moulton HM, Iversen PL, Fletcher S, Wilton S. Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD Gene Therapy. 13: 1373-1381. PMID 16724091 DOI: 10.1038/Sj.Gt.3302800 |
0.337 |
|
| 2006 |
Enterlein S, Warfield KL, Swenson DL, Stein DA, Smith JL, Gamble CS, Kroeker AD, Iversen PL, Bavari S, Mühlberger E. VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice. Antimicrobial Agents and Chemotherapy. 50: 984-93. PMID 16495261 DOI: 10.1128/Aac.50.3.984-993.2006 |
0.362 |
|
| 2006 |
Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S. Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers. Plos Pathogens. 2: e1. PMID 16415982 DOI: 10.1371/Journal.Ppat.0020001 |
0.316 |
|
| 2006 |
Holden KL, Stein DA, Pierson TC, Ahmed AA, Clyde K, Iversen PL, Harris E. Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. Virology. 344: 439-52. PMID 16214197 DOI: 10.1016/J.Virol.2005.08.034 |
0.317 |
|
| 2005 |
van den Born E, Stein DA, Iversen PL, Snijder EJ. Antiviral activity of morpholino oligomers designed to block various aspects of Equine arteritis virus amplification in cell culture. The Journal of General Virology. 86: 3081-90. PMID 16227231 DOI: 10.1099/Vir.0.81158-0 |
0.375 |
|
| 2005 |
Amantana A, Iversen PL. Pharmacokinetics and biodistribution of phosphorodiamidate morpholino antisense oligomers. Current Opinion in Pharmacology. 5: 550-5. PMID 16087398 DOI: 10.1016/J.Coph.2005.07.001 |
0.334 |
|
| 2005 |
Alonso M, Stein DA, Thomann E, Moulton HM, Leong JC, Iversen P, Mourich DV. Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers. Journal of Fish Diseases. 28: 399-410. PMID 16083445 DOI: 10.1111/J.1365-2761.2005.00641.X |
0.35 |
|
| 2005 |
Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM. Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity. Bioconjugate Chemistry. 16: 959-66. PMID 16029037 DOI: 10.1021/Bc0501045 |
0.319 |
|
| 2005 |
Neuman BW, Stein DA, Kroeker AD, Churchill MJ, Kim AM, Kuhn P, Dawson P, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ. Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers. Journal of Virology. 79: 9665-76. PMID 16014928 DOI: 10.1128/Jvi.79.15.9665-9676.2005 |
0.363 |
|
| 2005 |
Devi GR, Beer TM, Corless CL, Arora V, Weller DL, Iversen PL. In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3930-8. PMID 15897595 DOI: 10.1158/1078-0432.Ccr-04-2091 |
0.31 |
|
| 2005 |
Kinney RM, Huang CY, Rose BC, Kroeker AD, Dreher TW, Iversen PL, Stein DA. Inhibition of dengue virus serotypes 1 to 4 in vero cell cultures with morpholino oligomers. Journal of Virology. 79: 5116-28. PMID 15795296 DOI: 10.1128/Jvi.79.8.5116-5128.2005 |
0.342 |
|
| 2005 |
Deas TS, Binduga-Gajewska I, Tilgner M, Ren P, Stein DA, Moulton HM, Iversen PL, Kauffman EB, Kramer LD, Shi PY. Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication. Journal of Virology. 79: 4599-609. PMID 15795246 DOI: 10.1128/Jvi.79.8.4599-4609.2005 |
0.332 |
|
| 2005 |
Kipshidze N, Tsapenko M, Iversen P, Burger D. Antisense therapy for restenosis following percutaneous coronary intervention. Expert Opinion On Biological Therapy. 5: 79-89. PMID 15709911 DOI: 10.1517/14712598.5.1.79 |
0.337 |
|
| 2005 |
Deere J, Iversen P, Geller BL. Antisense Phosphorodiamidate Morpholino Oligomer Length and Target Position Effects on Gene-Specific Inhibition in Escherichia coli Antimicrobial Agents and Chemotherapy. 49: 249-255. PMID 15616302 DOI: 10.1128/Aac.49.1.249-255.2005 |
0.354 |
|
| 2004 |
Arora V, Devi GR, Iversen PL. Neutrally charged phosphorodiamidate morpholino antisense oligomers: uptake, efficacy and pharmacokinetics. Current Pharmaceutical Biotechnology. 5: 431-9. PMID 15544491 DOI: 10.2174/1389201043376706 |
0.339 |
|
| 2004 |
Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ. Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth. Journal of Virology. 78: 5891-9. PMID 15140987 DOI: 10.1128/Jvi.78.11.5891-5899.2004 |
0.393 |
|
| 2004 |
Moulton HM, Nelson MH, Hatlevig SA, Reddy MT, Iversen PL. Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides. Bioconjugate Chemistry. 15: 290-9. PMID 15025524 DOI: 10.1021/Bc034221G |
0.317 |
|
| 2003 |
Geller BL, Deere JD, Stein DA, Kroeker AD, Moulton HM, Iversen PL. Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers Antimicrobial Agents and Chemotherapy. 47: 3233-3239. PMID 14506035 DOI: 10.1128/Aac.47.10.3233-3239.2003 |
0.326 |
|
| 2003 |
Moulton HM, Hase MC, Smith KM, Iversen PL. HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers. Antisense & Nucleic Acid Drug Development. 13: 31-43. PMID 12691534 DOI: 10.1089/108729003764097322 |
0.379 |
|
| 2003 |
Knapp DC, Mata JE, Reddy MT, Devi GR, Iversen PL. Resistance to chemotherapeutic drugs overcome by c-Myc inhibition in a Lewis lung carcinoma murine model. Anti-Cancer Drugs. 14: 39-47. PMID 12544257 DOI: 10.1097/00001813-200301000-00006 |
0.714 |
|
| 2002 |
Arora V, Hannah TL, Iversen PL, Brand RM. Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats. Pharmaceutical Research. 19: 1465-70. PMID 12425463 DOI: 10.1023/A:1020448430919 |
0.306 |
|
| 2002 |
Arora V, Cate ML, Ghosh C, Iversen PL. Phosphorodiamidate morpholino antisense oligomers inhibit expression of human cytochrome P450 3A4 and alter selected drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 757-62. PMID 12065433 DOI: 10.1124/Dmd.30.7.757 |
0.379 |
|
| 2002 |
Kipshidze NN, Kim HS, Iversen P, Yazdi HA, Bhargava B, New G, Mehran R, Tio F, Haudenschild C, Dangas G, Stone GW, Iyer S, Roubin GS, Leon MB, Moses JW. Intramural coronary delivery of advanced antisense oligonucleotides reduces neointimal formation in the porcine stent restenosis model Journal of the American College of Cardiology. 39: 1686-1691. PMID 12020498 DOI: 10.1016/S0735-1097(02)01830-2 |
0.309 |
|
| 2002 |
Arora V, Knapp DC, Reddy MT, Weller DD, Iversen PL. Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats. Journal of Pharmaceutical Sciences. 91: 1009-18. PMID 11948540 DOI: 10.1002/Jps.10088 |
0.349 |
|
| 2002 |
Ricker JL, Mata JE, Iversen PL, Gattone VH. c-myc antisense oligonucleotide treatment ameliorates murine ARPKD. Kidney International. 61: S125-31. PMID 11841626 DOI: 10.1046/J.1523-1755.2002.0610S1125.X |
0.691 |
|
| 2001 |
Stein DA, Skilling DE, Iversen PL, Smith AW. Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers. Antisense & Nucleic Acid Drug Development. 11: 317-25. PMID 11763348 DOI: 10.1089/108729001753231696 |
0.365 |
|
| 2001 |
Sharp JG, Bishop MR, Copple B, Greiner TC, Iversen PL, Jackson JD, Joshi SS, Benner EJ, Mann SL, Rao AK, Vose JM. Oligonucleotide enhanced cytotoxicity of Idarubicin for lymphoma cells. Leukemia & Lymphoma. 42: 417-27. PMID 11699407 DOI: 10.3109/10428190109064599 |
0.35 |
|
| 2001 |
Kipshidze N, Keane E, Stein D, Chawla P, Skrinska V, Shankar LR, Khanna A, Komorowski R, Haudenschild C, Iversen P, Leon MB, Keelan MH, Moses J. Local delivery of c-myc neutrally charged antisense oligonucleotides with transport catheter inhibits myointimal hyperplasia and positively affects vascular remodeling in the rabbit balloon injury model. Catheterization and Cardiovascular Interventions. 54: 247-256. PMID 11590694 DOI: 10.1002/Ccd.1277 |
0.31 |
|
| 2001 |
Brand RM, Hannah TL, Norris J, Iversen PL. Transdermal delivery of antisense oligonucleotides can induce changes in gene expression in vivo. Antisense & Nucleic Acid Drug Development. 11: 1-6. PMID 11258617 DOI: 10.1089/108729001750072074 |
0.353 |
|
| 2001 |
Ghosh C, Iversen PL. Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers. Antisense & Nucleic Acid Drug Development. 10: 263-74. PMID 10984120 DOI: 10.1089/108729000421448 |
0.353 |
|
| 2000 |
Mata JE, Bishop MR, Tarantolo SR, Angel CR, Swanson SA, Iversen PL. Evidence of enhanced iron excretion during systemic phosphorothioate oligodeoxynucleotide treatment. Journal of Toxicology. Clinical Toxicology. 38: 383-7. PMID 10930054 DOI: 10.1081/Clt-100100947 |
0.677 |
|
| 2000 |
Hudziak RM, Summerton J, Weller DD, Iversen PL. Antiproliferative effects of steric blocking phosphorodiamidate morpholino antisense agents directed against c-myc. Antisense & Nucleic Acid Drug Development. 10: 163-76. PMID 10905553 DOI: 10.1089/Oli.1.2000.10.163 |
0.38 |
|
| 2000 |
Mata JE, Jackson JD, Joshi SS, Tracewell WG, Pirruccello SJ, Murphy BJ, Bishop MR, Iversen PL. Pharmacokinetics and in vivo effects of a six-base phosphorothioate oligodeoxynucleotide with anticancer and hematopoietic activities in swine. Journal of Hematotherapy & Stem Cell Research. 9: 205-14. PMID 10813533 DOI: 10.1089/152581600319414 |
0.707 |
|
| 2000 |
Ghosh C, Stein D, Weller D, Iversen P. Evaluation of antisense mechanisms of action Methods in Enzymology. 313: 135-143. PMID 10595352 DOI: 10.1016/S0076-6879(00)13008-3 |
0.348 |
|
| 1999 |
Iversen PL, Cornish KG, Iversen LJ, Mata JE, Bylund DB. Bolus intravenous injection of phosphorothioate oligonucleotides causes hypotension by acting as alpha(1)-adrenergic receptor antagonists. Toxicology and Applied Pharmacology. 160: 289-96. PMID 10544063 DOI: 10.1006/Taap.1999.8771 |
0.694 |
|
| 1999 |
Page TJ, Mata JE, Bridge JA, Siebler JC, Neff JR, Iversen PL. The cytotoxic effects of single-stranded telomere mimics on OMA-BL1 cells. Experimental Cell Research. 252: 41-9. PMID 10502398 DOI: 10.1006/Excr.1999.4613 |
0.723 |
|
| 1998 |
Arora V, Iversen PL, Ebadi M. Manipulation of metallothionein expression in the regenerating rat liver using antisense oligonucleotides. Biochemical and Biophysical Research Communications. 246: 711-8. PMID 9618277 DOI: 10.1006/Bbrc.1998.8612 |
0.322 |
|
| 1997 |
Benner E, Bishop MR, Agarwal N, Iversen P, Joshi SS. Combination of antisense oligonucleotide and low-dose chemotherapy in hematological malignancies. Journal of Pharmacological and Toxicological Methods. 37: 229-35. PMID 9279778 DOI: 10.1016/S1056-8719(97)00034-8 |
0.313 |
|
| 1997 |
Takeda A, Hisada H, Okada S, Mata JE, Ebadi M, Iversen PL. Tumor cell growth is inhibited by suppressing metallothionein-I synthesis. Cancer Letters. 116: 145-9. PMID 9215857 DOI: 10.1016/S0304-3835(97)00172-9 |
0.691 |
|
| 1997 |
Mata JE, Joshi SS, Palen B, Pirruccello SJ, Jackson JD, Elias N, Page TJ, Medlin KL, Iversen PL. A hexameric phosphorothioate oligonucleotide telomerase inhibitor arrests growth of Burkitt's lymphoma cells in vitro and in vivo. Toxicology and Applied Pharmacology. 144: 189-97. PMID 9169084 DOI: 10.1006/Taap.1997.8103 |
0.728 |
|
| 1997 |
Rao AK, Kuszynski CA, Benner E, Iversen PL, Jackson JD, Bishop MR, Joshi SS. Increased growth inhibition of human chronic myelogenous leukemic cells by a combination of c-myb antisense oligonucleotide and 4- hydroxyperoxycyclophosphamide in vitro International Journal of Oncology. 11: 281-287. DOI: 10.3892/Ijo.11.2.281 |
0.334 |
|
| 1996 |
Tracewell W, Desjardins J, Iversen P. In vivo modulation of the rat cytochrome P450 1A1 by double-stranded phosphorothioate oligodeoxynucleotides. Toxicology and Applied Pharmacology. 135: 179-84. PMID 8545825 DOI: 10.1006/Taap.1995.1221 |
0.335 |
|
| 1995 |
Wu AG, Joshi SS, Chan WC, Iversen PL, Jackson JD, Kessinger A, Pirruccello SJ, Sanger WG, Sharp JG, Verbik DJ. Effects of BCR-ABL antisense oligonucleotides (AS-ODN) on human chronic myeloid leukemic cells: AS-ODN as effective purging agents. Leukemia & Lymphoma. 20: 67-76. PMID 8750625 DOI: 10.3109/10428199509054755 |
0.34 |
|
| 1995 |
Iversen PL, Copple BL, Tewary HK. Pharmacology and toxicology of phosphorothioate oligonucleotides in the mouse, rat, monkey and man. Toxicology Letters. 82: 425-30. PMID 8597088 DOI: 10.1016/0378-4274(95)03572-9 |
0.323 |
|
| 1995 |
Ebadi M, Iversen PL. Metallothionein in carcinogenesis and cancer chemotherapy. General Pharmacology. 25: 1297-310. PMID 7896039 DOI: 10.1016/0306-3623(94)90152-X |
0.31 |
|
| 1995 |
DiBaise JK, Ebadi M, Iversen PL. Patterns of cellular uptake and effects on cell survival using antimetallothionein oligodeoxyribonucleotide conjugates in vitro. Biological Signals. 3: 140-9. PMID 7849801 DOI: 10.1159/000109537 |
0.363 |
|
| 1995 |
Desjardins J, Mata J, Brown T, Graham D, Zon G, Iversen P. Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides modulate CYP2B1 expression in vivo. Journal of Drug Targeting. 2: 477-485. PMID 7773609 DOI: 10.3109/10611869509015917 |
0.726 |
|
| 1995 |
Wang M, Mata J, Price CE, Iversen PL, Godfrey M. Prenatal and presymptomatic diagnosis of the Marfan syndrome using fluorescence PCR and an automated sequencer. Prenatal Diagnosis. 15: 499-507. PMID 7659684 DOI: 10.1002/Pd.1970150602 |
0.684 |
|
| 1995 |
Copple BL, Gmeiner WM, Iversen PL. Reaction between metabolically activated acetaminophen and phosphorothioate oligonucleotides. Toxicology and Applied Pharmacology. 133: 53-63. PMID 7597710 DOI: 10.1006/Taap.1995.1126 |
0.312 |
|
| 1994 |
Bayever E, Haines KM, Iversen PL, Ruddon RW, Pirruccello SJ, Mountjoy CP, Arneson MA, Smith LJ. Selective cytotoxicity to human leukemic myeloblasts produced by oligodeoxyribonucleotide phosphorothioates complementary to p53 nucleotide sequences. Leukemia & Lymphoma. 12: 223-31. PMID 8167553 DOI: 10.3109/10428199409059593 |
0.328 |
|
| 1994 |
Takeda A, Norris JS, Iversen PL, Ebadi M. Antisense oligonucleotide of c-myc discriminates between zinc- and dexamethasone-induced synthesis of metallothionein. Pharmacology. 48: 119-26. PMID 8134403 DOI: 10.1159/000139170 |
0.35 |
|
| 1994 |
Iversen PL, Mata J, Tracewell WG, Zon G. Pharmacokinetics of an antisense phosphorothioate oligodeoxynucleotide against rev from human immunodeficiency virus type 1 in the adult male rat following single injections and continuous infusion Antisense Research and Development. 4: 43-52. PMID 8061515 DOI: 10.1089/Ard.1994.4.43 |
0.711 |
|
| 1993 |
Bayever E, Iversen PL, Bishop MR, Sharp JG, Tewary HK, Arneson MA, Pirruccello SJ, Ruddon RW, Kessinger A, Zon G. Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: initial results of a phase I trial. Antisense Research and Development. 3: 383-90. PMID 8155979 DOI: 10.1089/Ard.1993.3.383 |
0.327 |
|
| 1993 |
Iversen PL, Zhu S, Meyer A, Zon G. Cellular uptake and subcellular distribution of phosphorothioate oligonucleotides into cultured cells. Antisense Research and Development. 2: 211-22. PMID 1490072 DOI: 10.1089/Ard.1992.2.211 |
0.324 |
|
| 1993 |
Iversen PL, Ebadi M. Antisense oligonucleotide-mediated inhibition of metallothionein protein synthesis in neuroblastoma IMR 32 and Chang liver cells in culture. Biological Signals. 1: 57-64. PMID 1307915 DOI: 10.1159/000109311 |
0.362 |
|
| 1992 |
Iversen PL, Crouse D, Zon G, Perry G. Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible Antisense Research and Development. 2: 223-233. PMID 1490073 DOI: 10.1089/Ard.1992.2.223 |
0.332 |
|
| 1992 |
Iversen PL, Mata JE, Ebadi M. Synthetic antisense oligonucleotide probes the essentiality of metallothionein gene. Biological Signals. 1: 293-9. PMID 1307930 DOI: 10.1159/000109334 |
0.734 |
|
| 1992 |
Chang N, Liu AY-, Song Y, Pang SF, Bourreau J-, Kitchener P, Kwan CY, Daniel EE, Sun B, Jin G, Iversen PL, Mata JE, Ebadi M. Contents Vol. 1, 1992 Neurosignals. 1. DOI: 10.1159/000109341 |
0.66 |
|
| 1992 |
Chang N, Liu AY-, Song Y, Pang SF, Bourreau J-, Kitchener P, Kwan CY, Daniel EE, Sun B, Jin G, Iversen PL, Mata JE, Ebadi M. Subject Index Vol. 1, 1992 Neurosignals. 1: 341-342. DOI: 10.1159/000109340 |
0.656 |
|
| 1987 |
Iversen PL, Siegel LI, Rahner K, Bresnick E. Synergy of phenobarbital and 3-methylcholanthrene in "superinduction" of cytochrome P-450c mRNA but not enzyme activity. Biochemical Pharmacology. 36: 3399-403. PMID 3675602 DOI: 10.1016/0006-2952(87)90317-0 |
0.309 |
|
| 1987 |
Iversen PL, Heiger WJ, Bresnick E, Hines RN. Structural details of the human cytochrome P-450c gene. Archives of Biochemistry and Biophysics. 256: 397-401. PMID 3606130 DOI: 10.1016/0003-9861(87)90460-7 |
0.328 |
|
| 1985 |
Hines RN, Levy JB, Conrad RD, Iversen PL, Shen ML, Renli AM, Bresnick E. Gene structure and nucleotide sequence for rat cytochrome P-450c Archives of Biochemistry and Biophysics. 237: 465-476. PMID 3838427 DOI: 10.1016/0003-9861(85)90300-5 |
0.319 |
|
| 1979 |
Schlegel RA, Iversen P, Rechsteiner M. The turnover of tRNAs microinjected into animal cells. Nucleic Acids Research. 5: 3715-29. PMID 214762 DOI: 10.1093/Nar/5.10.3715 |
0.31 |
|
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