William K. Kaufmann - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pathology, Cell Biology, Oncology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Cordeiro-Stone M, McNulty JJ, Sproul CD, Chastain PD, Gibbs-Flournoy E, Zhou Y, Carson C, Rao S, Mitchell DL, Simpson DA, Thomas NE, Ibrahim JG, Kaufmann WK. Effective Intra-S Checkpoint Responses to UVC in Primary Human Melanocytes and Melanoma Cell Lines. Pigment Cell & Melanoma Research. PMID 26437005 DOI: 10.1111/pcmr.12426  0.4
2015 Simpson DA, Lemonie N, Morgan DS, Gaddameedhi S, Kaufmann WK. Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity. Cancers. 7: 1072-90. PMID 26091525 DOI: 10.3390/cancers7020825  0.4
2015 Kaufmann WK. A bright quantum of time in the Cleaver Laboratory; a tribute and retrospective. Photochemistry and Photobiology. 91: 501-4. PMID 25754664 DOI: 10.1111/php.12384  0.4
2015 Smith-Roe SL, Nakamura J, Holley D, Chastain PD, Rosson GB, Simpson DA, Ridpath JR, Kaufman DG, Kaufmann WK, Bultman SJ. SWI/SNF complexes are required for full activation of the DNA-damage response. Oncotarget. 6: 732-45. PMID 25544751  0.4
2015 Chastain PD, Brylawski BP, Zhou YC, Rao S, Chu H, Ibrahim JG, Kaufmann WK, Cordeiro-Stone M. DNA damage checkpoint responses in the S phase of synchronized diploid human fibroblasts. Photochemistry and Photobiology. 91: 109-16. PMID 25316620 DOI: 10.1111/php.12361  0.4
2014 Kaufmann WK, Carson CC, Omolo B, Filgo AJ, Sambade MJ, Simpson DA, Shields JM, Ibrahim JG, Thomas NE. Mechanisms of chromosomal instability in melanoma. Environmental and Molecular Mutagenesis. 55: 457-71. PMID 24616037 DOI: 10.1002/em.21859  0.4
2014 Nikolaishvilli-Feinberg N, Cohen SM, Midkiff B, Zhou Y, Olorvida M, Ibrahim JG, Omolo B, Shields JM, Thomas NE, Groben PA, Kaufmann WK, Miller CR. Development of DNA damage response signaling biomarkers using automated, quantitative image analysis. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 62: 185-96. PMID 24309508 DOI: 10.1369/0022155413516469  0.4
2013 Sproul CD, Mitchell DL, Rao S, Ibrahim JG, Kaufmann WK, Cordeiro-Stone M. Cyclobutane Pyrimidine Dimer Density as a Predictive Biomarker of the Biological Effects of Ultraviolet Radiation in Normal Human Fibroblast. Photochemistry and Photobiology. PMID 24148148 DOI: 10.1111/php.12194  0.4
2013 Sproul CD, Rao S, Ibrahim JG, Kaufmann WK, Cordeiro-Stone M. Is activation of the intra-S checkpoint in human fibroblasts an important factor in protection against UV-induced mutagenesis? Cell Cycle (Georgetown, Tex.). 12: 3555-63. PMID 24091629 DOI: 10.4161/cc.26590  0.4
2013 Zhang L, Simpson DA, Innes CL, Chou J, Bushel PR, Paules RS, Kaufmann WK, Zhou T. Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals. Physiological Genomics. 45: 907-16. PMID 23943852 DOI: 10.1152/physiolgenomics.00064.2013  0.4
2013 Kaufmann WK, Anderson CW. Compensation, crosstalk and sequestering: the currency of checkpoints in cancer. Cell Cycle (Georgetown, Tex.). 12: 1163-4. PMID 23549170 DOI: 10.4161/cc.24486  0.4
2013 Omolo B, Carson C, Chu H, Zhou Y, Simpson DA, Hesse JE, Paules RS, Nyhan KC, Ibrahim JG, Kaufmann WK. A prognostic signature of G(2) checkpoint function in melanoma cell lines. Cell Cycle (Georgetown, Tex.). 12: 1071-82. PMID 23454897 DOI: 10.4161/cc.24067  0.4
2013 Lakhter AJ, Sahu RP, Sun Y, Kaufmann WK, Androphy EJ, Travers JB, Naidu SR. Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. The Journal of Investigative Dermatology. 133: 2247-54. PMID 23370537 DOI: 10.1038/jid.2013.56  0.4
2013 Kesseler KJ, Blinov ML, Elston TC, Kaufmann WK, Simpson DA. A predictive mathematical model of the DNA damage G2 checkpoint. Journal of Theoretical Biology. 320: 159-69. PMID 23266715 DOI: 10.1016/j.jtbi.2012.12.011  0.4
2013 Smith-Roe SL, Patel SS, Zhou Y, Simpson DA, Rao S, Ibrahim JG, Cordeiro-Stone M, Kaufmann WK. Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts. Cell Cycle (Georgetown, Tex.). 12: 332-45. PMID 23255133 DOI: 10.4161/cc.23177  0.4
2013 Prasad RY, Chastain PD, Nikolaishvili-Feinberg N, Smeester L, Kaufmann WK, Fry RC. Titanium dioxide nanoparticles activate the ATM-Chk2 DNA damage response in human dermal fibroblasts. Nanotoxicology. 7: 1111-9. PMID 22770119 DOI: 10.3109/17435390.2012.710659  0.4
2012 Kaufmann WK. Mutational showers during carcinogenesis. Pigment Cell & Melanoma Research. 25: 566-8. PMID 22765291 DOI: 10.1111/j.1755-148X.2012.01034.x  0.4
2012 Jeffries CD, Johnson CR, Zhou T, Simpson DA, Kaufmann WK. A flexible and qualitatively stable model for cell cycle dynamics including DNA damage effects. Gene Regulation and Systems Biology. 6: 55-66. PMID 22553421 DOI: 10.4137/GRSB.S8476  0.4
2012 Carson C, Omolo B, Chu H, Zhou Y, Sambade MJ, Peters EC, Tompkins P, Simpson DA, Thomas NE, Fan C, Sarasin A, Dessen P, Shields JM, Ibrahim JG, Kaufmann WK. A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines. Pigment Cell & Melanoma Research. 25: 514-26. PMID 22540896 DOI: 10.1111/j.1755-148X.2012.01010.x  0.4
2011 Gaddameedhi S, Selby CP, Kaufmann WK, Smart RC, Sancar A. Control of skin cancer by the circadian rhythm. Proceedings of the National Academy of Sciences of the United States of America. 108: 18790-5. PMID 22025708 DOI: 10.1073/pnas.1115249108  0.4
2011 Kaufmann WK. What's going on at stalled forks? Cell Cycle (Georgetown, Tex.). 10: 3048. PMID 21908973 DOI: 10.4161/cc.10.18.16993  0.4
2011 Smith-Roe SL, Patel SS, Simpson DA, Zhou YC, Rao S, Ibrahim JG, Kaiser-Rogers KA, Cordeiro-Stone M, Kaufmann WK. Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 1618-24. PMID 21508667 DOI: 10.4161/cc.10.10.15613  0.4
2011 Sambade MJ, Peters EC, Thomas NE, Kaufmann WK, Kimple RJ, Shields JM. Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 98: 394-9. PMID 21295875 DOI: 10.1016/j.radonc.2010.12.017  0.4
2010 Gaddameedhi S, Kemp MG, Reardon JT, Shields JM, Smith-Roe SL, Kaufmann WK, Sancar A. Similar nucleotide excision repair capacity in melanocytes and melanoma cells. Cancer Research. 70: 4922-30. PMID 20501836 DOI: 10.1158/0008-5472.CAN-10-0095  0.4
2010 Bower JJ, Zhou Y, Zhou T, Simpson DA, Arlander SJ, Paules RS, Cordeiro-Stone M, Kaufmann WK. Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM. Cell Cycle (Georgetown, Tex.). 9: 1617-28. PMID 20372057  0.4
2010 Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang TH, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-Kaçmaz K. Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. The Journal of Biological Chemistry. 285: 16562-71. PMID 20233725 DOI: 10.1074/jbc.M110.110304  0.4
2010 Kaufmann WK. The human intra-S checkpoint response to UVC-induced DNA damage. Carcinogenesis. 31: 751-65. PMID 19793801 DOI: 10.1093/carcin/bgp230  0.4
2009 Kaufmann WK. Analysis of the topoisomerase II-dependent decatenation G2 checkpoint and checkpoint kinases in human cells. Methods in Molecular Biology (Clifton, N.J.). 582: 155-66. PMID 19763949 DOI: 10.1007/978-1-60761-340-4_13  0.4
2009 Chen B, Simpson DA, Zhou Y, Mitra A, Mitchell DL, Cordeiro-Stone M, Kaufmann WK. Human papilloma virus type16 E6 deregulates CHK1 and sensitizes human fibroblasts to environmental carcinogens independently of its effect on p53. Cell Cycle (Georgetown, Tex.). 8: 1775-87. PMID 19411857  0.4
2009 Kaufmann WK. Living with reduced replicative helicase protein. Cell Cycle (Georgetown, Tex.). 8: 1468-9. PMID 19411831  0.4
2009 Zhou T, Chou J, Watkins PB, Kaufmann WK. Toxicogenomics: transcription profiling for toxicology assessment. Exs. 99: 325-66. PMID 19157067 DOI: 10.1007/978-3-7643-8336-7_12  0.4
2009 Tran N, Qu PP, Simpson DA, Lindsey-Boltz L, Guan X, Schmitt CP, Ibrahim JG, Kaufmann WK. In silico construction of a protein interaction landscape for nucleotide excision repair. Cell Biochemistry and Biophysics. 53: 101-14. PMID 19156361 DOI: 10.1007/s12013-009-9042-y  0.4
2008 Nikolaishvili-Feinberg N, Jenkins GS, Nevis KR, Staus DP, Scarlett CO, Unsal-Kaçmaz K, Kaufmann WK, Cordeiro-Stone M. Ubiquitylation of proliferating cell nuclear antigen and recruitment of human DNA polymerase eta. Biochemistry. 47: 4141-50. PMID 18321066 DOI: 10.1021/bi702329h  0.4
2008 Kaufmann WK, Nevis KR, Qu P, Ibrahim JG, Zhou T, Zhou Y, Simpson DA, Helms-Deaton J, Cordeiro-Stone M, Moore DT, Thomas NE, Hao H, Liu Z, Shields JM, Scott GA, et al. Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression. The Journal of Investigative Dermatology. 128: 175-87. PMID 17597816 DOI: 10.1038/sj.jid.5700935  0.4
2007 Chou JW, Zhou T, Kaufmann WK, Paules RS, Bushel PR. Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes. Bmc Bioinformatics. 8: 427. PMID 17980031 DOI: 10.1186/1471-2105-8-427  0.4
2007 Kesseler KJ, Kaufmann WK, Reardon JT, Elston TC, Sancar A. A mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreading. Journal of Theoretical Biology. 249: 361-75. PMID 17869273 DOI: 10.1016/j.jtbi.2007.07.025  0.4
2007 Zhou T, Chou J, Zhou Y, Simpson DA, Cao F, Bushel PR, Paules RS, Kaufmann WK. Ataxia telangiectasia-mutated dependent DNA damage checkpoint functions regulate gene expression in human fibroblasts. Molecular Cancer Research : McR. 5: 813-22. PMID 17699107 DOI: 10.1158/1541-7786.MCR-07-0104  0.4
2007 Beyer RP, Fry RC, Lasarev MR, McConnachie LA, Meira LB, Palmer VS, Powell CL, Ross PK, Bammler TK, Bradford BU, Cranson AB, Cunningham ML, Fannin RD, Higgins GM, Hurban P, ... ... Kaufmann WK, et al. Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 326-37. PMID 17562736 DOI: 10.1093/toxsci/kfm150  0.4
2007 Zhou T, Chou J, Mullen TE, Elkon R, Zhou Y, Simpson DA, Bushel PR, Paules RS, Lobenhofer EK, Hurban P, Kaufmann WK. Identification of primary transcriptional regulation of cell cycle-regulated genes upon DNA damage. Cell Cycle (Georgetown, Tex.). 6: 972-81. PMID 17404513  0.4
2007 Shields JM, Thomas NE, Cregger M, Berger AJ, Leslie M, Torrice C, Hao H, Penland S, Arbiser J, Scott G, Zhou T, Bar-Eli M, Bear JE, Der CJ, Kaufmann WK, et al. Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma. Cancer Research. 67: 1502-12. PMID 17308088 DOI: 10.1158/0008-5472.CAN-06-3311  0.4
2007 Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK. The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Molecular and Cellular Biology. 27: 3131-42. PMID 17296725 DOI: 10.1128/MCB.02190-06  0.4
2007 Heffernan TP, Unsal-Kaçmaz K, Heinloth AN, Simpson DA, Paules RS, Sancar A, Cordeiro-Stone M, Kaufmann WK. Cdc7-Dbf4 and the human S checkpoint response to UVC. The Journal of Biological Chemistry. 282: 9458-68. PMID 17276990 DOI: 10.1074/jbc.M611292200  0.4
2006 Ryan JL, Kaufmann WK, Raab-Traub N, Oglesbee SE, Carey LA, Gulley ML. Clonal evolution of lymphoblastoid cell lines. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1193-200. PMID 17053803 DOI: 10.1038/labinvest.3700472  0.4
2006 Kaufmann WK, Filatov L, Oglesbee SE, Simpson DA, Lotano MA, McKeen HD, Sawyer LR, Moore DT, Millikan RC, Cordeiro-Stone M, Carey LA. Radiation clastogenesis and cell cycle checkpoint function as functional markers of breast cancer risk. Carcinogenesis. 27: 2519-27. PMID 16777992 DOI: 10.1093/carcin/bgl103  0.4
2006 Zhou T, Chou JW, Simpson DA, Zhou Y, Mullen TE, Medeiros M, Bushel PR, Paules RS, Yang X, Hurban P, Lobenhofer EK, Kaufmann WK. Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environmental Health Perspectives. 114: 553-9. PMID 16581545 DOI: 10.1289/ehp.8026  0.4
2006 Innes CL, Heinloth AN, Flores KG, Sieber SO, Deming PB, Bushel PR, Kaufmann WK, Paules RS. ATM requirement in gene expression responses to ionizing radiation in human lymphoblasts and fibroblasts. Molecular Cancer Research : McR. 4: 197-207. PMID 16547157 DOI: 10.1158/1541-7786.MCR-05-0154  0.4
2005 Bammler T, Beyer RP, Bhattacharya S, Boorman GA, Boyles A, Bradford BU, Bumgarner RE, Bushel PR, Chaturvedi K, Choi D, Cunningham ML, Deng S, Dressman HK, Fannin RD, Farin FM, ... ... Kaufmann WK, et al. Standardizing global gene expression analysis between laboratories and across platforms. Nature Methods. 2: 351-6. PMID 15846362 DOI: 10.1038/nmeth754  0.4
2005 Unsal-Kaçmaz K, Mullen TE, Kaufmann WK, Sancar A. Coupling of human circadian and cell cycles by the timeless protein. Molecular and Cellular Biology. 25: 3109-16. PMID 15798197 DOI: 10.1128/MCB.25.8.3109-3116.2005  0.4
2004 Troester MA, Hoadley KA, Sørlie T, Herbert BS, Børresen-Dale AL, Lønning PE, Shay JW, Kaufmann WK, Perou CM. Cell-type-specific responses to chemotherapeutics in breast cancer. Cancer Research. 64: 4218-26. PMID 15205334 DOI: 10.1158/0008-5472.CAN-04-0107  0.4
2003 Doherty SC, McKeown SR, McKelvey-Martin V, Downes CS, Atala A, Yoo JJ, Simpson DA, Kaufmann WK. Cell cycle checkpoint function in bladder cancer. Journal of the National Cancer Institute. 95: 1859-68. PMID 14679155  0.4
2002 Heffernan TP, Simpson DA, Frank AR, Heinloth AN, Paules RS, Cordeiro-Stone M, Kaufmann WK. An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Molecular and Cellular Biology. 22: 8552-61. PMID 12446774  0.4
2002 Kaufmann WK, Campbell CB, Simpson DA, Deming PB, Filatov L, Galloway DA, Zhao XJ, Creighton AM, Downes CS. Degradation of ATM-independent decatenation checkpoint function in human cells is secondary to inactivation of p53 and correlated with chromosomal destabilization. Cell Cycle (Georgetown, Tex.). 1: 210-9. PMID 12429935  0.4
2002 Deming PB, Flores KG, Downes CS, Paules RS, Kaufmann WK. ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase. The Journal of Biological Chemistry. 277: 36832-8. PMID 12147700 DOI: 10.1074/jbc.M206109200  0.4
2002 Cordeiro-Stone M, Frank A, Bryant M, Oguejiofor I, Hatch SB, McDaniel LD, Kaufmann WK. DNA damage responses protect xeroderma pigmentosum variant from UVC-induced clastogenesis. Carcinogenesis. 23: 959-65. PMID 12082017  0.4
2001 Deming PB, Cistulli CA, Zhao H, Graves PR, Piwnica-Worms H, Paules RS, Downes CS, Kaufmann WK. The human decatenation checkpoint. Proceedings of the National Academy of Sciences of the United States of America. 98: 12044-9. PMID 11593014 DOI: 10.1073/pnas.221430898  0.4
1998 Cistulli CA, Kaufmann WK. p53-dependent signaling sustains DNA replication and enhances clonogenic survival in 254 nm ultraviolet-irradiated human fibroblasts. Cancer Research. 58: 1993-2002. PMID 9581844  1
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