Raymond N. DuBois - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Cell Biology, Oncology, Molecular Biology

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang D, Fu L, Wei J, Xiong Y, DuBois RN. PPARdelta mediates the effect of dietary fat in promoting colorectal cancer metastasis. Cancer Research. PMID 31239272 DOI: 10.1158/0008-5472.CAN-19-0384  0.32
2018 Wang D, DuBois RN. Role of prostanoids in gastrointestinal cancer. The Journal of Clinical Investigation. PMID 29733297 DOI: 10.1172/JCI97953  0.32
2017 Wang D, Sun H, Wei J, Cen B, DuBois RN. CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer. Cancer Research. PMID 28455419 DOI: 10.1158/0008-5472.CAN-16-3199  0.32
2016 Kim SH, Park YY, Cho SN, Margalit O, Wang D, DuBois RN. Krüppel-Like Factor 12 Promotes Colorectal Cancer Growth through Early Growth Response Protein 1. Plos One. 11: e0159899. PMID 27442508 DOI: 10.1371/journal.pone.0159899  0.32
2015 Wang D, DuBois RN. The Role of Prostaglandin E2 in Tumor-Associated Immunosuppression. Trends in Molecular Medicine. PMID 26711015 DOI: 10.1016/j.molmed.2015.11.003  0.32
2015 Wang D, DuBois RN. Immunosuppression associated with chronic inflammation in the tumor microenvironment. Carcinogenesis. 36: 1085-93. PMID 26354776 DOI: 10.1093/carcin/bgv123  0.32
2015 Wang D, Fu L, Sun H, Guo L, DuBois RN. Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice. Gastroenterology. PMID 26261008 DOI: 10.1053/j.gastro.2015.07.064  0.32
2014 Wang D, DuBois RN. PPARδ and PGE2 signaling pathways communicate and connect inflammation to colorectal cancer. Inflammation and Cell Signaling. 1. PMID 26290896 DOI: 10.14800/ics.338  0.32
2014 Kim SH, Margalit O, Katoh H, Wang D, Wu H, Xia D, Holla VR, Yang P, DuBois RN. CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models. Investigational New Drugs. 32: 1105-12. PMID 25085205 DOI: 10.1007/s10637-014-0144-z  1
2014 Wang D, DuBois RN. Myeloid-derived suppressor cells link inflammation to cancer. Oncoimmunology. 3: e28581. PMID 25054088 DOI: 10.4161/onci.28581  0.32
2014 Wang D, Fu L, Ning W, Guo L, Sun X, Dey SK, Chaturvedi R, Wilson KT, DuBois RN. Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 111: 7084-9. PMID 24763687 DOI: 10.1073/pnas.1324233111  1
2013 Wang D, DuBois RN. An inflammatory mediator, prostaglandin E2, in colorectal cancer. Cancer Journal (Sudbury, Mass.). 19: 502-10. PMID 24270349 DOI: 10.1097/PPO.0000000000000003  0.32
2013 Katoh H, Wang D, Daikoku T, Sun H, Dey SK, Dubois RN. CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis. Cancer Cell. 24: 631-44. PMID 24229710 DOI: 10.1016/j.ccr.2013.10.009  1
2013 Kim SH, Wang D, Park YY, Katoh H, Margalit O, Sheffer M, Wu H, Holla VR, Lee JS, DuBois RN. HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways. Cancer Letters. 341: 159-65. PMID 23916472 DOI: 10.1016/j.canlet.2013.07.028  1
2013 Pirman DA, Efuet E, Ding XP, Pan Y, Tan L, Fischer SM, DuBois RN, Yang P. Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry. Plos One. 8: e61379. PMID 23658609 DOI: 10.1371/journal.pone.0061379  1
2013 Wang D, DuBois RN. Urinary PGE-M: a promising cancer biomarker. Cancer Prevention Research (Philadelphia, Pa.). 6: 507-10. PMID 23636051 DOI: 10.1158/1940-6207.CAPR-13-0153  0.32
2013 Wang D, DuBois RN. The role of anti-inflammatory drugs in colorectal cancer. Annual Review of Medicine. 64: 131-44. PMID 23020877 DOI: 10.1146/annurev-med-112211-154330  0.32
2013 Wang D, Margalit O, DuBois RN. Metronomic topotecan for colorectal cancer: a promising new option. Gut. 62: 190-1. PMID 22684481 DOI: 10.1136/gutjnl-2012-302410  0.32
2012 Margalit O, Wang D, Dubois RN. PPARγ agonists target aromatase via both PGE2 and BRCA1. Cancer Prevention Research (Philadelphia, Pa.). 5: 1169-72. PMID 23041473 DOI: 10.1158/1940-6207.CAPR-12-0365  0.32
2012 Cantley LC, Dalton WS, DuBois RN, Finn OJ, Futreal PA, Golub TR, Hait WN, Lozano G, Maris JM, Nelson WG, Sawyers CL, Schreiber SL, Spitz MR, Steeg PS. AACR Cancer Progress Report 2012. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: S1-100. PMID 22977188 DOI: 10.1158/1078-0432.CCR-12-2891  1
2012 Ross W, Lynch P, Raju G, Rodriguez A, Burke T, Hafemeister L, Hawk E, Wu X, Dubois RN, Mishra L. Biomarkers, bundled payments, and colorectal cancer care. Genes & Cancer. 3: 16-22. PMID 22893787 DOI: 10.1177/1947601912448958  1
2012 Lin M, Gu J, Eng C, Ellis LM, Hildebrandt MA, Lin J, Huang M, Calin GA, Wang D, Dubois RN, Hawk ET, Wu X. Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3982-91. PMID 22661538 DOI: 10.1158/1078-0432.CCR-11-2951  0.32
2012 Wang D, DuBois RN. The role of the PGE2-aromatase pathway in obesity-associated breast inflammation. Cancer Discovery. 2: 308-10. PMID 22576207 DOI: 10.1158/2159-8290.CD-12-0078  0.32
2012 Wang D, Dubois RN. Associations between obesity and cancer: the role of fatty acid synthase. Journal of the National Cancer Institute. 104: 343-5. PMID 22312133 DOI: 10.1093/jnci/djs010  0.32
2012 Xia D, Wang D, Kim SH, Katoh H, DuBois RN. Prostaglandin E2 promotes intestinal tumor growth via DNA methylation. Nature Medicine. 18: 224-6. PMID 22270723 DOI: 10.1038/nm.2608  1
2012 Wang D, Dubois RN. Epoxyeicosatrienoic acids: a double-edged sword in cardiovascular diseases and cancer. The Journal of Clinical Investigation. 122: 19-22. PMID 22182836 DOI: 10.1172/JCI61453  0.32
2011 Wang D, Xia D, Dubois RN. The Crosstalk of PTGS2 and EGF Signaling Pathways in Colorectal Cancer. Cancers. 3: 3894-908. PMID 24213116 DOI: 10.3390/cancers3043894  0.32
2011 Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, ... ... Dubois RN, et al. APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. The Journal of Clinical Investigation. 121: 4526-36. PMID 21985787 DOI: 10.1172/JCI45008  1
2011 Kim SH, Park YY, Kim SW, Lee JS, Wang D, DuBois RN. ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression. Cancer Research. 71: 7010-20. PMID 21937683 DOI: 10.1158/0008-5472.CAN-11-1262  0.32
2010 Peddareddigari VG, Wang D, Dubois RN. The tumor microenvironment in colorectal carcinogenesis. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 3: 149-66. PMID 21209781 DOI: 10.1007/s12307-010-0038-3  0.32
2010 Wang D, DuBois RN. Therapeutic potential of peroxisome proliferator-activated receptors in chronic inflammation and colorectal cancer. Gastroenterology Clinics of North America. 39: 697-707. PMID 20951925 DOI: 10.1016/j.gtc.2010.08.014  0.32
2010 Speirs CK, Jernigan KK, Kim SH, Cha YI, Lin F, Sepich DS, DuBois RN, Lee E, Solnica-Krezel L. Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Development (Cambridge, England). 137: 1327-37. PMID 20332150 DOI: 10.1242/dev.045971  1
2010 Wang D, Dubois RN. Eicosanoids and cancer. Nature Reviews. Cancer. 10: 181-93. PMID 20168319 DOI: 10.1038/nrc2809  0.32
2010 Xia D, Holla VR, Wang D, Menter DG, DuBois RN. HEF1 is a crucial mediator of the proliferative effects of prostaglandin E(2) on colon cancer cells. Cancer Research. 70: 824-31. PMID 20068165 DOI: 10.1158/0008-5472.CAN-09-2105  0.32
2009 Wang D, Dubois RN, Richmond A. The role of chemokines in intestinal inflammation and cancer. Current Opinion in Pharmacology. 9: 688-96. PMID 19734090 DOI: 10.1016/j.coph.2009.08.003  0.32
2008 Holla VR, Backlund MG, Yang P, Newman RA, DuBois RN. Regulation of prostaglandin transporters in colorectal neoplasia. Cancer Prevention Research (Philadelphia, Pa.). 1: 93-9. PMID 19138942 DOI: 10.1158/1940-6207.CAPR-07-0009  1
2008 Backlund MG, Mann JR, Holla VR, Shi Q, Daikoku T, Dey SK, DuBois RN. Repression of 15-hydroxyprostaglandin dehydrogenase involves histone deacetylase 2 and snail in colorectal cancer. Cancer Research. 68: 9331-7. PMID 19010907 DOI: 10.1158/0008-5472.CAN-08-2893  1
2008 Wang D, Wang H, Ning W, Backlund MG, Dey SK, DuBois RN. Loss of cannabinoid receptor 1 accelerates intestinal tumor growth. Cancer Research. 68: 6468-76. PMID 18676872 DOI: 10.1158/0008-5472.CAN-08-0896  1
2008 Pedchenko TV, Gonzalez AL, Wang D, DuBois RN, Massion PP. Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer. American Journal of Respiratory Cell and Molecular Biology. 39: 689-96. PMID 18566335 DOI: 10.1165/rcmb.2007-0426OC  1
2008 Wang D, Dubois RN. Peroxisome proliferator-activated receptors and progression of colorectal cancer. Ppar Research. 2008: 931074. PMID 18551185 DOI: 10.1155/2008/931074  0.32
2008 Wang D, DuBois RN. Pro-inflammatory prostaglandins and progression of colorectal cancer. Cancer Letters. 267: 197-203. PMID 18406516 DOI: 10.1016/j.canlet.2008.03.004  0.32
2007 Wang H, Xie H, Sun X, Tranguch S, Zhang H, Jia X, Wang D, Das SK, Desvergne B, Wahli W, DuBois RN, Dey SK. Stage-specific integration of maternal and embryonic peroxisome proliferator-activated receptor delta signaling is critical to pregnancy success. The Journal of Biological Chemistry. 282: 37770-82. PMID 17965409 DOI: 10.1074/jbc.M706577200  0.44
2007 Wang D, DuBois RN. Measurement of eicosanoids in cancer tissues. Methods in Enzymology. 433: 27-50. PMID 17954227 DOI: 10.1016/S0076-6879(07)33002-4  0.32
2007 Lee SH, Rangiah K, Williams MV, Wehr AY, DuBois RN, Blair IA. Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells. Chemical Research in Toxicology. 20: 1665-75. PMID 17910482 DOI: 10.1021/tx700130p  1
2007 Buchanan FG, Holla V, Katkuri S, Matta P, DuBois RN. Targeting cyclooxygenase-2 and the epidermal growth factor receptor for the prevention and treatment of intestinal cancer. Cancer Research. 67: 9380-8. PMID 17909047 DOI: 10.1158/0008-5472.CAN-07-0710  0.32
2007 Daikoku T, Tranguch S, Chakrabarty A, Wang D, Khabele D, Orsulic S, Morrow JD, Dubois RN, Dey SK. Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer. Cancer Research. 67: 5285-92. PMID 17545608 DOI: 10.1158/0008-5472.CAN-07-0828  0.44
2007 Horikawa Y, Otaka M, Komatsu K, Jin M, Odashima M, Wada I, Matsuhashi T, Ohba R, Oyake J, Hatakeyama N, Dubois RN, Watanabe S. MEK activation suppresses CPT11-induced apoptosis in rat intestinal epithelial cells through a COX-2-dependent mechanism. Digestive Diseases and Sciences. 52: 2757-65. PMID 17393318 DOI: 10.1007/s10620-007-9798-0  1
2007 Wang D, DuBois RN. Inflammatory mediators and nuclear receptor signaling in colorectal cancer. Cell Cycle (Georgetown, Tex.). 6: 682-5. PMID 17374999 DOI: 10.4161/cc.6.6.4030  0.32
2007 Cha YI, DuBois RN. NSAIDs and cancer prevention: targets downstream of COX-2. Annual Review of Medicine. 58: 239-52. PMID 17100552 DOI: 10.1146/annurev.med.57.121304.131253  0.56
2006 Wang D, Wang H, Guo Y, Ning W, Katkuri S, Wahli W, Desvergne B, Dey SK, DuBois RN. Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 103: 19069-74. PMID 17148604 DOI: 10.1073/pnas.0607948103  0.44
2006 Komatsu K, Buchanan FG, Otaka M, Jin M, Odashima M, Horikawa Y, Watanabe S, Dubois RN. Gene expression profiling following constitutive activation of MEK1 and transformation of rat intestinal epithelial cells. Molecular Cancer. 5: 63. PMID 17112382 DOI: 10.1186/1476-4598-5-63  1
2006 Mann JR, Backlund MG, Buchanan FG, Daikoku T, Holla VR, Rosenberg DW, Dey SK, DuBois RN. Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression. Cancer Research. 66: 6649-56. PMID 16818638 DOI: 10.1158/0008-5472.CAN-06-1787  1
2006 Backlund MG, Mann JR, Wang D, Dubois RN. Ras up-regulation of cyclooxygenase-2. Methods in Enzymology. 407: 401-10. PMID 16757341 DOI: 10.1016/S0076-6879(05)07033-3  1
2006 Wang D, Wang H, Brown J, Daikoku T, Ning W, Shi Q, Richmond A, Strieter R, Dey SK, DuBois RN. CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. The Journal of Experimental Medicine. 203: 941-51. PMID 16567391 DOI: 10.1084/jem.20052124  0.44
2006 Cha YI, Kim SH, Sepich D, Buchanan FG, Solnica-Krezel L, DuBois RN. Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes & Development. 20: 77-86. PMID 16391234 DOI: 10.1101/gad.1374506  1
2006 Cha YI, Solnica-Krezel L, DuBois RN. Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins. Developmental Biology. 289: 263-72. PMID 16310177 DOI: 10.1016/j.ydbio.2005.10.013  1
2005 Mann JR, Backlund MG, DuBois RN. Mechanisms of disease: Inflammatory mediators and cancer prevention. Nature Clinical Practice. Oncology. 2: 202-10. PMID 16264935 DOI: 10.1038/ncponc0140  1
2005 Backlund MG, Mann JR, Dubois RN. Mechanisms for the prevention of gastrointestinal cancer: the role of prostaglandin E2. Oncology. 69: 28-32. PMID 16210874 DOI: 10.1159/000086629  1
2005 Peek RM, Mohla S, DuBois RN. Inflammation in the genesis and perpetuation of cancer: summary and recommendations from a national cancer institute-sponsored meeting. Cancer Research. 65: 8583-6. PMID 16204020 DOI: 10.1158/0008-5472.CAN-05-1777  1
2005 Musiek ES, Gao L, Milne GL, Han W, Everhart MB, Wang D, Backlund MG, DuBois RN, Zanoni G, Vidari G, Blackwell TS, Morrow JD. Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages. The Journal of Biological Chemistry. 280: 35562-70. PMID 16100121 DOI: 10.1074/jbc.M504785200  1
2005 Komatsu K, Buchanan FG, Katkuri S, Morrow JD, Inoue H, Otaka M, Watanabe S, DuBois RN. Oncogenic potential of MEK1 in rat intestinal epithelial cells is mediated via cyclooxygenase-2. Gastroenterology. 129: 577-90. PMID 16083714 DOI: 10.1016/j.gastro.2005.06.003  1
2005 Cha YI, Kim SH, Solnica-Krezel L, Dubois RN. Cyclooxygenase-1 signaling is required for vascular tube formation during development. Developmental Biology. 282: 274-83. PMID 15936346 DOI: 10.1016/j.ydbio.2005.03.014  1
2005 Wang D, Mann JR, DuBois RN. The role of prostaglandins and other eicosanoids in the gastrointestinal tract. Gastroenterology. 128: 1445-61. PMID 15887126  0.32
2005 Daikoku T, Wang D, Tranguch S, Morrow JD, Orsulic S, DuBois RN, Dey SK. Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. Cancer Research. 65: 3735-44. PMID 15867369 DOI: 10.1158/0008-5472.CAN-04-3814  0.44
2005 Wang D, Buchanan FG, Wang H, Dey SK, DuBois RN. Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. Cancer Research. 65: 1822-9. PMID 15753380 DOI: 10.1158/0008-5472.CAN-04-3671  0.44
2005 Buchanan FG, McReynolds M, Couvillon A, Kam Y, Holla VR, DuBois RN, Exton JH. Requirement of phospholipase D1 activity in H-RasV12-induced transformation Proceedings of the National Academy of Sciences of the United States of America. 102: 1638-1642. PMID 15668389 DOI: 10.1073/pnas.0406698102  1
2005 Backlund MG, Mann JR, Holla VR, Buchanan FG, Tai HH, Musiek ES, Milne GL, Katkuri S, DuBois RN. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. The Journal of Biological Chemistry. 280: 3217-23. PMID 15542609 DOI: 10.1074/jbc.M411221200  1
2005 Holla VR, Wang D, Brown JR, Mann JR, Katkuri S, DuBois RN. Prostaglandin E2 regulates the complement inhibitor CD55/decay-accelerating factor in colorectal cancer. The Journal of Biological Chemistry. 280: 476-83. PMID 15520008 DOI: 10.1074/jbc.M407403200  0.32
2004 Wang D, Mann JR, DuBois RN. WNT and cyclooxygenase-2 cross-talk accelerates adenoma growth. Cell Cycle (Georgetown, Tex.). 3: 1512-5. PMID 15539957 DOI: 10.4161/cc.3.12.1288  0.32
2004 Buchanan FG, Chang W, Sheng H, Shao J, Morrow JD, DuBois RN. Up-regulation of the enzymes involved in prostacyclin synthesis via Ras induces vascular endothelial growth factor. Gastroenterology. 127: 1391-400. PMID 15521009  0.32
2004 Wang D, Wang H, Shi Q, Katkuri S, Walhi W, Desvergne B, Das SK, Dey SK, DuBois RN. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell. 6: 285-95. PMID 15380519 DOI: 10.1016/j.ccr.2004.08.011  0.44
2004 Wang H, Guo Y, Wang D, Kingsley PJ, Marnett LJ, Das SK, DuBois RN, Dey SK. Aberrant cannabinoid signaling impairs oviductal transport of embryos. Nature Medicine. 10: 1074-80. PMID 15378054 DOI: 10.1038/nm1104  0.44
2004 Wang D, Dubois RN. Cyclooxygenase-2: a potential target in breast cancer. Seminars in Oncology. 31: 64-73. PMID 15052544  0.32
2004 Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN. Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nature Medicine. 10: 245-7. PMID 14758356 DOI: 10.1038/nm993  1
2004 Wang D, DuBois RN. Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch. Proceedings of the National Academy of Sciences of the United States of America. 101: 415-6. PMID 14707264 DOI: 10.1073/pnas.0307640100  0.32
2003 Crosby CG, DuBois RN. The cyclooxygenase-2 pathway as a target for treatment or prevention of cancer. Expert Opinion On Emerging Drugs. 8: 1-7. PMID 14610907 DOI: 10.1517/14728214.8.1.1  1
2003 Gupta RA, Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK, DuBois RN. Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. Cancer Research. 63: 906-11. PMID 12615701  1
2003 Gupta RA, Sarraf P, Mueller E, Brockman JA, Prusakiewicz JJ, Eng C, Willson TM, DuBois RN. Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. The Journal of Biological Chemistry. 278: 22669-77. PMID 12591919 DOI: 10.1074/jbc.M300637200  1
2003 Daikoku T, Matsumoto H, Gupta RA, Das SK, Gassmann M, DuBois RN, Dey SK. Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function of HIFs during early pregnancy. The Journal of Biological Chemistry. 278: 7683-91. PMID 12482866 DOI: 10.1074/jbc.M211390200  1
2003 Gupta RA, Sarraf P, Brockman JA, Shappell SB, Raftery LA, Willson TM, DuBois RN. Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22. The Journal of Biological Chemistry. 278: 7431-8. PMID 12468551 DOI: 10.1074/jbc.M208076200  1
2002 Gupta RA, DuBois RN, Wallace MC. New avenues for the prevention of colorectal cancer: targeting cyclo-oxygenase-2 activity. Best Practice & Research. Clinical Gastroenterology. 16: 945-56. PMID 12473300 DOI: 10.1053/bega.2002.0353  1
2002 Gupta RA, Dubois RN. Controversy: PPARgamma as a target for treatment of colorectal cancer. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G266-9. PMID 12121872 DOI: 10.1152/ajpgi.00486.2001  1
2002 Kozak KR, Gupta RA, Moody JS, Ji C, Boeglin WE, DuBois RN, Brash AR, Marnett LJ. 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist. The Journal of Biological Chemistry. 277: 23278-86. PMID 11956198 DOI: 10.1074/jbc.M201084200  1
2002 Gupta RA, DuBois RN. Cyclooxygenase-2 inhibitor therapy for the prevention of esophageal adenocarcinoma in Barrett's esophagus. Journal of the National Cancer Institute. 94: 406-7. PMID 11904306  1
2001 Gupta RA, Dubois RN. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nature Reviews. Cancer. 1: 11-21. PMID 11900248 DOI: 10.1038/35094017  1
2001 Gupta RA, Polk DB, Krishna U, Israel DA, Yan F, DuBois RN, Peek RM. Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells. The Journal of Biological Chemistry. 276: 31059-66. PMID 11397815 DOI: 10.1074/jbc.M104141200  1
2001 Gupta RA, Brockman JA, Sarraf P, Willson TM, DuBois RN. Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells. The Journal of Biological Chemistry. 276: 29681-7. PMID 11397807 DOI: 10.1074/jbc.M103779200  1
2001 Shappell SB, Gupta RA, Manning S, Whitehead R, Boeglin WE, Schneider C, Case T, Price J, Jack GS, Wheeler TM, Matusik RJ, Brash AR, Dubois RN. 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells. Cancer Research. 61: 497-503. PMID 11212240  1
2000 Gupta RA, Tan J, Krause WF, Geraci MW, Willson TM, Dey SK, DuBois RN. Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 97: 13275-80. PMID 11087869 DOI: 10.1073/pnas.97.24.13275  1
2000 Gupta RA, DuBois RN. Combinations for cancer prevention. Nature Medicine. 6: 974-5. PMID 10973312 DOI: 10.1038/79664  1
2000 Gupta RA, DuBois RN. Translational studies on Cox-2 inhibitors in the prevention and treatment of colon cancer. Annals of the New York Academy of Sciences. 910: 196-204; discussion . PMID 10911914  1
1999 Lim H, Gupta RA, Ma WG, Paria BC, Moller DE, Morrow JD, DuBois RN, Trzaskos JM, Dey SK. Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes & Development. 13: 1561-74. PMID 10385625  1
1998 Brockman JA, Gupta RA, Dubois RN. Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology. 115: 1049-55. PMID 9797355 DOI: 10.1016/S0016-5085(98)70072-1  1
1998 Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, Lipsky PE. Cyclooxygenase in biology and disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1063-73. PMID 9737710  1
1998 Gupta RA, DuBois RN. Aspirin, NSAIDS, and colon cancer prevention: mechanisms? Gastroenterology. 114: 1095-8. PMID 9606094 DOI: 10.1016/S0016-5085(98)70330-0  1
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