Manuel Buchwald - Publications

University of Toronto, Toronto, ON, Canada 
Cell Biology

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Gordon SM, Alon N, Buchwald M. FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway. The Journal of Biological Chemistry. 280: 36118-25. PMID 16127171 DOI: 10.1074/jbc.M507758200  1
2004 Brodeur I, Goulet I, Tremblay CS, Charbonneau C, Delisle MC, Godin C, Huard C, Khandjian EW, Buchwald M, Lévesque G, Carreau M. Regulation of the Fanconi anemia group C protein through proteolytic modification. The Journal of Biological Chemistry. 279: 4713-20. PMID 14625294 DOI: 10.1074/jbc.M301291200  1
2003 Wong JC, Gokgoz N, Alon N, Andrulis IL, Buchwald M. Cloning and mutation analysis of ZFP276 as a candidate tumor suppressor in breast cancer. Journal of Human Genetics. 48: 668-71. PMID 14605947 DOI: 10.1007/s10038-003-0088-1  0.84
2003 Wong JC, Alon N, Mckerlie C, Huang JR, Meyn MS, Buchwald M. Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia. Human Molecular Genetics. 12: 2063-76. PMID 12913077  0.84
2003 Gordon SM, Buchwald M. Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems. Blood. 102: 136-41. PMID 12649160 DOI: 10.1182/blood-2002-11-3517  1
2002 Yang Y, McKerlie C, Borenstein SH, Lu Z, Schito M, Chamberlain JW, Buchwald M. Transgenic expression in mouse lung reveals distinct biological roles for the adenovirus type 5 E1A 243- and 289-amino-acid proteins. Journal of Virology. 76: 8910-9. PMID 12163610 DOI: 10.1128/JVI.76.17.8910-8919.2002  1
2002 Wong JC, Buchwald M. Disease model: Fanconi anemia. Trends in Molecular Medicine. 8: 139-42. PMID 11879775  0.84
2001 Hadjur S, Ung K, Wadsworth L, Dimmick J, Rajcan-Separovic E, Scott RW, Buchwald M, Jirik FR. Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase. Blood. 98: 1003-11. PMID 11493445 DOI: 10.1182/blood.V98.4.1003  1
2001 Cumming RC, Lightfoot J, Beard K, Youssoufian H, O'Brien PJ, Buchwald M. Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1. Nature Medicine. 7: 814-20. PMID 11433346 DOI: 10.1038/89937  0.4
2000 Wong JC, Alon N, Norga K, Kruyt FA, Youssoufian H, Buchwald M. Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA. Genomics. 67: 273-83. PMID 10936049 DOI: 10.1006/geno.2000.6252  1
2000 Riazi MA, Brinkman-Mills P, Nguyen T, Pan H, Phan S, Ying F, Roe BA, Tochigi J, Shimizu Y, Minoshima S, Shimizu N, Buchwald M, McDermid HE. The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome. Genomics. 64: 277-85. PMID 10756095 DOI: 10.1006/geno.1999.6099  1
1999 Carreau M, Alon N, Bosnoyan-Collins L, Joenje H, Buchwald M. Drug sensitivity spectra in Fanconi anemia lymphoblastoid cell lines of defined complementation groups. Mutation Research. 435: 103-9. PMID 10526221 DOI: 10.1016/s0921-8777(99)00041-5  0.36
1999 Lightfoot J, Alon N, Bosnoyan-Collins L, Buchwald M. Characterization of regions functional in the nuclear localization of the Fanconi anemia group A protein. Human Molecular Genetics. 8: 1007-15. PMID 10332032 DOI: 10.1093/hmg/8.6.1007  0.36
1999 Buchwald M, O'Brodovich H. HSC clinical trials controversy continues. Hospital for Sick Children. Nature Medicine. 5: 2-3. PMID 9883819 DOI: 10.1038/4667  1
1998 Tang SJ, Suen TC, McInnes RR, Buchwald M. Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins. The Journal of Biological Chemistry. 273: 25356-63. PMID 9738002 DOI: 10.1074/jbc.273.39.25356  1
1998 Escarceller M, Buchwald M, Singleton BK, Jeggo PA, Jackson SP, Moustacchi E, Papadopoulo D. Fanconi anemia C gene product plays a role in the fidelity of blunt DNA end-joining. Journal of Molecular Biology. 279: 375-85. PMID 9642044 DOI: 10.1006/jmbi.1998.1784  1
1998 Tang SJ, Hoodless PA, Lu Z, Breitman ML, McInnes RR, Wrana JL, Buchwald M. The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development Development. 125: 1877-1887. PMID 9550720  1
1997 Chow YH, O'Brodovich H, Plumb J, Wen Y, Sohn KJ, Lu Z, Zhang F, Lukacs GL, Tanswell AK, Hui CC, Buchwald M, Hu J. Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways. Proceedings of the National Academy of Sciences of the United States of America. 94: 14695-700. PMID 9405675 DOI: 10.1073/pnas.94.26.14695  1
1997 Kent G, Iles R, Bear CE, Huan LJ, Griesenbach U, McKerlie C, Frndova H, Ackerley C, Gosselin D, Radzioch D, O'Brodovich H, Tsui LC, Buchwald M, Tanswell AK. Lung disease in mice with cystic fibrosis. The Journal of Clinical Investigation. 100: 3060-9. PMID 9399953 DOI: 10.1172/JCI119861  1
1997 Ching Ying Wong J, Alon N, Buchwald M. Cloning of the bovine and rat Fanconi anemia group C cDNA. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 522-5. PMID 9196001 DOI: 10.1007/s003359900490  0.36
1996 Cumming RC, Liu JM, Youssoufian H, Buchwald M. Suppression of apoptosis in hematopoietic factor-dependent progenitor cell lines by expression of the FAC gene. Blood. 88: 4558-67. PMID 8977247  0.4
1996 Kent G, Oliver M, Foskett JK, Frndova H, Durie P, Forstner J, Forstner GG, Riordan JR, Percy D, Buchwald M. Phenotypic abnormalities in long-term surviving cystic fibrosis mice. Pediatric Research. 40: 233-41. PMID 8827771 DOI: 10.1203/00006450-199608000-00008  1
1996 Savoia A, Centra M, Ianzano L, Pio De Cillis G, Buchwald M, Zelante L. Molecular characterization of Fanconi anaemia group C (FAC) gene polymorphisms Molecular and Cellular Probes. 10: 213-218. PMID 8799375 DOI: 10.1006/mcpr.1996.0029  1
1996 Chen M, Tomkins DJ, Auerbach W, McKerlie C, Youssoufian H, Liu L, Gan O, Carreau M, Auerbach A, Groves T, Guidos CJ, Freedman MH, Cross J, Percy DH, Dick JE, ... ... Buchwald M, et al. Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nature Genetics. 12: 448-51. PMID 8630504 DOI: 10.1038/ng0496-448  1
1996 Youssoufian H, Li Y, Martin ME, Buchwald M. Induction of Fanconi anemia cellular phenotype in human 293 cells by overexpression of a mutant FAC allele Journal of Clinical Investigation. 97: 957-962. PMID 8613549 DOI: 10.1172/JCI118519  1
1995 Savoia A, Centra M, Lanzano L, De Cillis GP, Zelante L, Buchwald M. Characterization of the 5' region of the fanconi anaemia group c (FACC) gene Human Molecular Genetics. 4: 1321-1326. PMID 7581369 DOI: 10.1093/hmg/4.8.1321  1
1994 Melmer G, Buchwald M. Screening cosmid libraries with oligonucleotides corresponding to splice-site consensus sequences. Genetic Analysis, Techniques and Applications. 11: 39-42. PMID 7917499 DOI: 10.1016/1050-3862(94)90059-0  1
1994 Rochwerger L, Dho S, Parker L, Foskett JK, Buchwald M. Estrogen-dependent expression of the cystic fibrosis transmembrane regulator gene in a novel uterine epithelial cell line Journal of Cell Science. 107: 2439-2448. PMID 7531199  1
1994 Becq F, Jensen TJ, Chang XB, Savoia A, Rommens JM, Tsui LC, Buchwald M, Riordan JR, Hanrahan JW. Phosphatase inhibitors activate normal and defective CFTR chloride channels. Proceedings of the National Academy of Sciences of the United States of America. 91: 9160-4. PMID 7522329 DOI: 10.1073/pnas.91.19.9160  1
1994 Tizzano EF, O'Brodovich H, Chitayat D, Bènichou JC, Buchwald M. Regional expression of CFTR in developing human respiratory tissues. American Journal of Respiratory Cell and Molecular Biology. 10: 355-62. PMID 7510983 DOI: 10.1165/ajrcmb.10.4.7510983  1
1993 Gibson RA, Buchwald M, Roberts RG, Mathew CG. Characterisation of the exon structure of the fanconi anaemia group C gene by vectorette PCR Human Molecular Genetics. 2: 35-38. PMID 8490620 DOI: 10.1093/hmg/2.1.35  1
1993 Kuehl BL, Buchwald M, Rauth AM. Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C. Oncology Research. 5: 213-21. PMID 8123941  1
1993 Gibson RA, Savola A, Buchwald M, G.mathew C. Ecori RFLP in the fanconi anaemia complementation group C gene (FACC) Human Molecular Genetics. 2: 1509. PMID 7902167 DOI: 10.1093/hmg/2.9.1509-a  1
1993 Wevrick R, Barker JE, Nadeau JH, Szpirer C, Buchwald M. Mapping of the murine and rat Facc genes and assessment of flexed-tail as a candidate mouse homolog of Fanconi anemia group C. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 440-4. PMID 7690622 DOI: 10.1007/BF00296818  1
1993 Wevrick R, Clarke CA, Buchwald M. Cloning and analysis of the murine fanconi anemia group C cDNA Human Molecular Genetics. 2: 655-662. PMID 7689006 DOI: 10.1093/hmg/2.6.655  1
1993 Trezise AE, Linder CC, Grieger D, Thompson EW, Meunier H, Griswold MD, Buchwald M. CFTR expression is regulated during both the cycle of the seminiferous epithelium and the oestrous cycle of rodents. Nature Genetics. 3: 157-64. PMID 7684647 DOI: 10.1038/ng0293-157  1
1992 Sood R, Bear C, Auerbach W, Reyes E, Jensen T, Kartner N, Riordan JR, Buchwald M. Regulation of CFTR expression function during differentiation of intestinal epithelial cells Embo Journal. 11: 2487-2494. PMID 1378393  1
1992 Strathdee CA, Duncan AM, Buchwald M. Evidence for at least four Fanconi anaemia genes including FACC on chromosome 9. Nature Genetics. 1: 196-8. PMID 1303234 DOI: 10.1038/ng0692-196  1
1992 Melmer G, Buchwald M. Identification of genes using oligonucleotides corresponding to splice site consensus sequences. Human Molecular Genetics. 1: 433-8. PMID 1284528 DOI: 10.1093/hmg/1.6.433  1
1991 Tsui LC, Buchwald M. Biochemical and molecular genetics of cystic fibrosis. Advances in Human Genetics. 20: 153-266, 311-2. PMID 1724873 DOI: 10.1007/978-1-4684-5958-6_4  1
1991 Buchwald M, Sood R, Auerbach W. Regulation of expression of CFTR in human intestinal epithelial cells. Advances in Experimental Medicine and Biology. 290: 241-50; discussion 2. PMID 1719762 DOI: 10.1007/978-1-4684-5934-0_24  1
1991 Sakaguchi K, Harris PV, Ryan C, Buchwald M, Boyd JB. Alteration of a nuclease in Fanconi anemia Mutation Research-Dna Repair. 255: 31-38. PMID 1648664 DOI: 10.1016/0921-8777(91)90015-H  1
1990 Melmer G, Buchwald M. Use of short oligonucleotides to screen cosmid libraries for clones containing G/C-rich sequences. Dna and Cell Biology. 9: 377-85. PMID 2196904 DOI: 10.1089/dna.1990.9.377  1
1990 Melmer G, Sood R, Rommens J, Rego D, Tsui LC, Buchwald M. Isolation of clones on chromosome 7 that contain recognition sites for rare-cutting enzymes by oligonucleotide hybridization. Genomics. 7: 173-81. PMID 2161402 DOI: 10.1016/0888-7543(90)90538-6  1
1990 Burns J, Melmer G, Rommens JM, Riordan JR, Buchwald M. Identification of sequences of chromosome 7 that are expressed in sweat gland epithelial cells. Human Genetics. 85: 151-6. PMID 1973401 DOI: 10.1007/bf00193187  1
1990 Buchanan JA, Yeger H, Tabcharani JA, Jensen TJ, Auerbach W, Hanrahan JW, Riodan JR, Buchwald M. Transformed sweat gland and nasal epithelial cell lines from control and cystic fibrosis individuals. Journal of Cell Science. 95: 109-23. PMID 1693627  1
1989 Rommens JM, Iannuzzi MC, Kerem B, Drumm ML, Melmer G, Dean M, Rozmahel R, Cole JL, Kennedy D, Hidaka N. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science (New York, N.Y.). 245: 1059-65. PMID 2772657 DOI: 10.1126/science.2772657  1
1989 Buchwald M, Tsui LC, Riordan JR. The search for the cystic fibrosis gene. The American Journal of Physiology. 257: L47-52. PMID 2669523 DOI: 10.1152/ajplung.1989.257.2.L47  1
1989 Rommens JM, Zengerling-Lentes S, Kerem B, Melmer G, Buchwald M, Tsui LC. Physical localization of two DNA markers closely linked to the cystic fibrosis locus by pulsed-field gel electrophoresis. American Journal of Human Genetics. 45: 932-41. PMID 2589321  1
1989 Kerem B, Rommens JM, Buchanan JA, Markiewicz D, Cox TK, Chakravarti A, Buchwald M, Tsui LC. Identification of the cystic fibrosis gene: genetic analysis. Science (New York, N.Y.). 245: 1073-80. PMID 2570460 DOI: 10.1126/science.2570460  1
1989 Kerem BS, Buchanan JA, Durie P, Corey ML, Levison H, Rommens JM, Buchwald M, Tsui LC. DNA marker haplotype association with pancreatic sufficiency in cystic fibrosis. American Journal of Human Genetics. 44: 827-34. PMID 2567116  1
1988 Tsui LC, Buchwald M. No evidence for genetic heterogeneity in cystic fibrosis. American Journal of Human Genetics. 42: 184. PMID 3337109  1
1988 Duncan AM, Buchwald M, Tsui LC. In situ hybridization of two cloned chromosome 7 sequences tightly linked to the cystic fibrosis locus. Cytogenetics and Cell Genetics. 49: 309-10. PMID 3248389 DOI: 10.1159/000132684  1
1988 Tsui LC, Rommens JM, Burns J, Zengerling S, Riordan JR, Carlock LR, Grzeschik KH, Buchwald M. Progress towards cloning the cystic fibrosis gene Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 319: 263-273. PMID 2900520  1
1987 Zengerling S, Tsui LC, Grzeschik KH, Olek K, Riordan JR, Buchwald M. Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7. American Journal of Human Genetics. 40: 228-36. PMID 3472464  1
1987 Buchwald M, Tsui LC. Current status of the genetics of cystic fibrosis. Progress in Clinical and Biological Research. 254: 19-29. PMID 3324103  1
1987 Wainwright BJ, Tsui LC, Leppert M, Buchwald M, Estivill X, O'Connell P, Lathrop M, Lalouel JM, White R, Williamson R. Linkage of DNA probe B79a (D7S13) to cystic fibrosis. American Journal of Human Genetics. 41: 944-7. PMID 2890297  1
1987 Kaiser R, Weber J, Grzeschik KH, Edström JE, Driesel A, Zengerling S, Buchwald M, Tsui LC, Olek K. Microdissection and microcloning of the long arm of human chromosome 7. Molecular Biology Reports. 12: 3-6. PMID 2888014 DOI: 10.1007/bf00580643  1
1987 Riordan J, Burns J, Tsui LC, Reddy MM, Quinton P, Buchwald M. Utilization of cultured epithelial cells from the sweat gland in studies of the CF defect. Progress in Clinical and Biological Research. 254: 59-71. PMID 2448827  1
1986 Tsui LC, Zengerling S, Willard HF, Buchwald M. Mapping of the cystic fibrosis locus on chromosome 7. Cold Spring Harbor Symposia On Quantitative Biology. 51: 325-35. PMID 3472729 DOI: 10.1101/sqb.1986.051.01.038  1
1986 Tsui LC, Buetow K, Buchwald M. Genetic analysis of cystic fibrosis using linked DNA markers. American Journal of Human Genetics. 39: 720-8. PMID 3467587  1
1986 Schmiegelow K, Eiberg H, Tsui LC, Buchwald M, Phelan PD, Williamson R, Warwick W, Niebuhr E, Mohr J, Schwartz M. Linkage between the loci for cystic fibrosis and paraoxonase. Clinical Genetics. 29: 374-7. PMID 3017612 DOI: 10.1111/j.1399-0004.1986.tb00507.x  1
1985 Tsui LC, Cox DW, McAlpine PJ, Buchwald M. Cystic fibrosis: analysis of linkage of the disease locus to red cell and plasma protein markers. Cytogenetics and Cell Genetics. 39: 238-9. PMID 4042695 DOI: 10.1159/000132144  1
1985 Tsui LC, Zsiga M, Kennedy D, Plavsic N, Markiewicz D, Buchwald M. Cystic fibrosis: progress in mapping the disease locus using polymorphic DNA markers. I. Cytogenetics and Cell Genetics. 39: 299-301. PMID 3863749 DOI: 10.1159/000132162  1
1985 Knowlton RG, Cohen-Haguenauer O, Van Cong N, Frézal J, Brown VA, Barker D, Braman JC, Schumm JW, Tsui LC, Buchwald M, Donis-Keller H. A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7 Nature. 318: 380-382. PMID 2999611 DOI: 10.1038/318380a0  1
1985 Tsui LC, Buchwald M, Barker D, Braman JC, Knowlton R, Schumm JW, Eiberg H, Mohr J, Kennedy D, Plavsic N. Cystic fibrosis locus defined by a genetically linked polymorphic DNA marker. Science (New York, N.Y.). 230: 1054-7. PMID 2997931 DOI: 10.1126/science.2997931  1
1982 Tsui LC, Breitman ML, Siminovitch L, Buchwald M. Persistence of freely replicating SV40 recombinant molecules carrying a selectable marker in permissive simian cells. Cell. 30: 499-508. PMID 6291772 DOI: 10.1016/0092-8674(82)90247-1  1
1982 Breitman ML, Tsui LC, Buchwald M, Siminovitch L. Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells. Molecular and Cellular Biology. 2: 966-76. PMID 6290875  1
1974 Mankovitz R, Buchwald M, Baker RM. Isolation of ouabain-resistant human diploid fibroblasts Cell. 3: 221-226. PMID 4434471 DOI: 10.1016/0092-8674(74)90135-4  1
1970 Buchwald M, Murialdo H, Siminovitch L. The morphogenesis of bacteriophage lambda. II. Identification of the principal structural proteins. Virology. 42: 390-400. PMID 4923012 DOI: 10.1016/0042-6822(70)90282-5  1
1970 Buchwald M, Steed-Glaister P, Siminovitch L. The morphogenesis of bacteriophage lambda. I. Purification and characterization of lambda heads and lambda tails. Virology. 42: 375-89. PMID 4099070 DOI: 10.1016/0042-6822(70)90281-3  1
1969 Buchwald M, Siminovitch L. Production of serum-blocking material by mutants of the left arm of the λ chromosome Virology. 38: 1-7.  1
1968 Buchwald M, Jencks WP. Properties of the crustacyanins and the yellow lobster shell pigment. Biochemistry. 7: 844-59. PMID 5644143  1
1968 Buchwald M, Jencks WP. Optical properties of astaxanthin solutions and aggregates. Biochemistry. 7: 834-43. PMID 5644142  1
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