Brett Finlay - Publications

University of British Columbia, Vancouver, Vancouver, BC, Canada 
Cell Biology, Pathology

198 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Finlay BB, Amato KR, Azad M, Blaser MJ, Bosch TCG, Chu H, Dominguez-Bello MG, Ehrlich SD, Elinav E, Geva-Zatorsky N, Gros P, Guillemin K, Keck F, Korem T, McFall-Ngai MJ, et al. The hygiene hypothesis, the COVID pandemic, and consequences for the human microbiome. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33472859 DOI: 10.1073/pnas.2010217118  0.32
2016 van der Heijden J, Reynolds LA, Deng W, Mills A, Scholz R, Imami K, Foster LJ, Duong F, Finlay BB. Salmonella Rapidly Regulates Membrane Permeability To Survive Oxidative Stress. Mbio. 7. PMID 27507830 DOI: 10.1128/mBio.01238-16  0.52
2016 Arrieta MC, Sadarangani M, Brown EM, Russell SL, Nimmo M, Dean J, Turvey SE, Chan ES, Finlay BB. A humanized microbiota mouse model of ovalbumin-induced lung inflammation. Gut Microbes. 0. PMID 27115049 DOI: 10.1080/19490976.2016.1182293  0.52
2016 Law RJ, Law HT, Scurll JM, Scholz R, Santos AS, Shames SR, Deng W, Croxen MA, Li Y, de Hoog CL, van der Heijden J, Foster LJ, Guttman JA, Finlay BB. Quantitative Mass Spectrometry Identifies Novel Host Binding Partners for Pathogenic Escherichia coli Type III Secretion System Effectors. Journal of Proteome Research. PMID 27018634 DOI: 10.1021/acs.jproteome.6b00074  0.52
2015 Yang JS, Kim HJ, Kang SS, Kim KW, Kim DW, Yun CH, Park SJ, Seo HS, Finlay BB, Han SH. TLR2, but not TLR4, plays a predominant role in the immune responses to cholera vaccines. Journal of Leukocyte Biology. PMID 26078314 DOI: 10.1189/jlb.4A1014-498R  0.52
2015 Vogt SL, Peña-Díaz J, Finlay BB. Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens. Anaerobe. 34: 106-115. PMID 25958185 DOI: 10.1016/j.anaerobe.2015.05.002  0.52
2015 Scholz R, Imami K, Scott NE, Trimble WS, Foster LJ, Finlay BB. Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis. Molecular & Cellular Proteomics : McP. PMID 25944883 DOI: 10.1074/mcp.M114.046847  0.52
2015 Bhullar K, Zarepour M, Yu H, Yang H, Croxen M, Stahl M, Finlay BB, Turvey SE, Vallance BA. The serine protease autotransporter Pic modulates Citrobacter rodentium pathogenesis and its innate recognition by the host. Infection and Immunity. PMID 25895966 DOI: 10.1128/IAI.00025-15  0.52
2015 Burkinshaw BJ, Deng W, Lameignère E, Wasney GA, Zhu H, Worrall LJ, Finlay BB, Strynadka NC. Structural analysis of a specialized type III secretion system peptidoglycan-cleaving enzyme. The Journal of Biological Chemistry. 290: 10406-17. PMID 25678709 DOI: 10.1074/jbc.M115.639013  0.52
2015 Caballero-Flores GG, Croxen MA, Martínez-Santos VI, Finlay BB, Puente JL. Identification and regulation of a novel Citrobacter rodentium gut colonization fimbria (Gcf). Journal of Bacteriology. 197: 1478-91. PMID 25666139 DOI: 10.1128/JB.02486-14  0.64
2015 Waldor MK, Tyson G, Borenstein E, Ochman H, Moeller A, Finlay BB, Kong HH, Gordon JI, Nelson KE, Dabbagh K, Smith H. Where next for microbiome research? Plos Biology. 13: e1002050. PMID 25602283 DOI: 10.1371/journal.pbio.1002050  0.52
2015 Santos AS, Finlay BB. Bringing down the host: enteropathogenic and enterohaemorrhagic Escherichia coli effector-mediated subversion of host innate immune pathways. Cellular Microbiology. 17: 318-32. PMID 25588886 DOI: 10.1111/cmi.12412  0.52
2015 Russell SL, Gold MJ, Reynolds LA, Willing BP, Dimitriu P, Thorson L, Redpath SA, Perona-Wright G, Blanchet MR, Mohn WW, Finlay BB, McNagny KM. Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases. The Journal of Allergy and Clinical Immunology. 135: 100-9. PMID 25145536 DOI: 10.1016/j.jaci.2014.06.027  0.52
2014 Roberts ME, Bishop JL, Fan X, Beer JL, Kum WW, Krebs DL, Huang M, Gill N, Priatel JJ, Finlay BB, Harder KW. Lyn deficiency leads to increased microbiota-dependent intestinal inflammation and susceptibility to enteric pathogens. Journal of Immunology (Baltimore, Md. : 1950). 193: 5249-63. PMID 25339668 DOI: 10.4049/jimmunol.1302832  0.52
2014 Yurist-Doutsch S, Arrieta MC, Vogt SL, Finlay BB. Gastrointestinal microbiota-mediated control of enteric pathogens. Annual Review of Genetics. 48: 361-82. PMID 25251855 DOI: 10.1146/annurev-genet-120213-092421  0.52
2014 Reynolds LA, Smith KA, Filbey KJ, Harcus Y, Hewitson JP, Redpath SA, Valdez Y, Yebra MJ, Finlay BB, Maizels RM. Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites. Gut Microbes. 5: 522-32. PMID 25144609 DOI: 10.4161/gmic.32155  0.52
2014 Valdez Y, Brown EM, Finlay BB. Influence of the microbiota on vaccine effectiveness. Trends in Immunology. 35: 526-37. PMID 25113637 DOI: 10.1016/  0.52
2014 Collins JW, Keeney KM, Crepin VF, Rathinam VA, Fitzgerald KA, Finlay BB, Frankel G. Citrobacter rodentium: infection, inflammation and the microbiota. Nature Reviews. Microbiology. 12: 612-23. PMID 25088150 DOI: 10.1038/nrmicro3315  0.52
2014 Antunes LC, McDonald JA, Schroeter K, Carlucci C, Ferreira RB, Wang M, Yurist-Doutsch S, Hira G, Jacobson K, Davies J, Allen-Vercoe E, Finlay BB. Antivirulence activity of the human gut metabolome. Mbio. 5: e01183-14. PMID 25073640 DOI: 10.1128/mBio.01183-14  0.52
2014 Keeney KM, Yurist-Doutsch S, Arrieta MC, Finlay BB. Effects of antibiotics on human microbiota and subsequent disease. Annual Review of Microbiology. 68: 217-35. PMID 24995874 DOI: 10.1146/annurev-micro-091313-103456  0.52
2014 Wlodarska M, Thaiss CA, Nowarski R, Henao-Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB, Flavell RA. NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell. 156: 1045-59. PMID 24581500 DOI: 10.1016/j.cell.2014.01.026  0.52
2014 Kumar NS, Dullaghan EM, Finlay BB, Gong H, Reiner NE, Jon Paul Selvam J, Thorson LM, Campbell S, Vitko N, Richardson AR, Zoraghi R, Young RN. Discovery and optimization of a new class of pyruvate kinase inhibitors as potential therapeutics for the treatment of methicillin-resistant Staphylococcus aureus infections. Bioorganic & Medicinal Chemistry. 22: 1708-25. PMID 24508307 DOI: 10.1016/j.bmc.2014.01.020  0.52
2013 Brown EM, Arrieta MC, Finlay BB. A fresh look at the hygiene hypothesis: how intestinal microbial exposure drives immune effector responses in atopic disease. Seminars in Immunology. 25: 378-87. PMID 24209708 DOI: 10.1016/j.smim.2013.09.003  0.52
2013 Croxen MA, Law RJ, Scholz R, Keeney KM, Wlodarska M, Finlay BB. Recent advances in understanding enteric pathogenic Escherichia coli. Clinical Microbiology Reviews. 26: 822-80. PMID 24092857 DOI: 10.1128/CMR.00022-13  0.52
2013 Marchiando AM, Ramanan D, Ding Y, Gomez LE, Hubbard-Lucey VM, Maurer K, Wang C, Ziel JW, van Rooijen N, Nuñez G, Finlay BB, Mysorekar IU, Cadwell K. A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection. Cell Host & Microbe. 14: 216-24. PMID 23954160 DOI: 10.1016/j.chom.2013.07.013  0.52
2013 Bhavsar AP, Brown NF, Stoepel J, Wiermer M, Martin DD, Hsu KJ, Imami K, Ross CJ, Hayden MR, Foster LJ, Li X, Hieter P, Finlay BB. The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity. Plos Pathogens. 9: e1003518. PMID 23935490 DOI: 10.1371/journal.ppat.1003518  0.52
2013 Buckner MM, Antunes LC, Gill N, Russell SL, Shames SR, Finlay BB. 15-Deoxy-Δ12,14-prostaglandin J2 inhibits macrophage colonization by Salmonella enterica serovar Typhimurium. Plos One. 8: e69759. PMID 23922794 DOI: 10.1371/journal.pone.0069759  0.52
2013 Donnenberg MS, Finlay BB. Combating enteropathogenic Escherichia coli (EPEC) infections: the way forward. Trends in Microbiology. 21: 317-9. PMID 23815982 DOI: 10.1016/j.tim.2013.05.003  0.52
2013 Brown EM, Sadarangani M, Finlay BB. The role of the immune system in governing host-microbe interactions in the intestine Nature Immunology. 14: 660-667. PMID 23778793 DOI: 10.1038/ni.2611  0.52
2013 Sal-Man N, Setiaputra D, Scholz R, Deng W, Yu AC, Strynadka NC, Finlay BB. EscE and EscG are cochaperones for the type III needle protein EscF of enteropathogenic Escherichia coli. Journal of Bacteriology. 195: 2481-9. PMID 23524615 DOI: 10.1128/JB.00118-13  0.52
2013 Imami K, Bhavsar AP, Yu H, Brown NF, Rogers LD, Finlay BB, Foster LJ. Global impact of Salmonella pathogenicity island 2-secreted effectors on the host phosphoproteome. Molecular & Cellular Proteomics : McP. 12: 1632-43. PMID 23459991 DOI: 10.1074/mcp.M112.026161  0.52
2013 Olsen RL, Echtenkamp F, Cheranova D, Deng W, Finlay BB, Hardwidge PR. The enterohemorrhagic Escherichia coli effector protein NleF binds mammalian Tmp21. Veterinary Microbiology. 164: 164-70. PMID 23434013 DOI: 10.1016/j.vetmic.2013.01.028  0.52
2013 Keeney KM, Finlay BB. Microbiology: EHEC downregulates virulence in response to intestinal fucose. Current Biology : Cb. 23: R108-10. PMID 23391383 DOI: 10.1016/j.cub.2012.12.027  0.52
2013 Russell SL, Gold MJ, Willing BP, Thorson L, McNagny KM, Finlay BB. Perinatal antibiotic treatment affects murine microbiota, immune responses and allergic asthma. Gut Microbes. 4: 158-64. PMID 23333861 DOI: 10.4161/gmic.23567  0.52
2013 Kindrachuk J, Jenssen H, Elliott M, Nijnik A, Magrangeas-Janot L, Pasupuleti M, Thorson L, Ma S, Easton DM, Bains M, Finlay B, Breukink EJ, Georg-Sahl H, Hancock RE. Manipulation of innate immunity by a bacterial secreted peptide: lantibiotic nisin Z is selectively immunomodulatory. Innate Immunity. 19: 315-27. PMID 23109507 DOI: 10.1177/1753425912461456  0.52
2012 Bäckhed F, Fraser CM, Ringel Y, Sanders ME, Sartor RB, Sherman PM, Versalovic J, Young V, Finlay BB. Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications. Cell Host & Microbe. 12: 611-22. PMID 23159051 DOI: 10.1016/j.chom.2012.10.012  0.52
2012 Russell SL, Finlay BB. The impact of gut microbes in allergic diseases. Current Opinion in Gastroenterology. 28: 563-9. PMID 23010680 DOI: 10.1097/MOG.0b013e3283573017  0.52
2012 Prehna G, Li Y, Stoynov N, Okon M, Vuckovic M, McIntosh LP, Foster LJ, Finlay BB, Strynadka NC. The zinc regulated antivirulence pathway of Salmonella is a multiprotein immunoglobulin adhesion system. The Journal of Biological Chemistry. 287: 32324-37. PMID 22810234 DOI: 10.1074/jbc.M112.357210  0.52
2012 Deng W, Yu HB, de Hoog CL, Stoynov N, Li Y, Foster LJ, Finlay BB. Quantitative proteomic analysis of type III secretome of enteropathogenic Escherichia coli reveals an expanded effector repertoire for attaching/effacing bacterial pathogens. Molecular & Cellular Proteomics : McP. 11: 692-709. PMID 22661456 DOI: 10.1074/mcp.M111.013672  0.52
2012 Achtman AH, Pilat S, Law CW, Lynn DJ, Janot L, Mayer ML, Ma S, Kindrachuk J, Finlay BB, Brinkman FS, Smyth GK, Hancock RE, Schofield L. Effective adjunctive therapy by an innate defense regulatory peptide in a preclinical model of severe malaria. Science Translational Medicine. 4: 135ra64. PMID 22623740 DOI: 10.1126/scitranslmed.3003515  0.52
2012 Sal-Man N, Biemans-Oldehinkel E, Sharon D, Croxen MA, Scholz R, Foster LJ, Finlay BB. EscA is a crucial component of the type III secretion system of enteropathogenic Escherichia coli. Journal of Bacteriology. 194: 2819-28. PMID 22447907 DOI: 10.1128/JB.00103-12  0.52
2012 Russell SL, Gold MJ, Hartmann M, Willing BP, Thorson L, Wlodarska M, Gill N, Blanchet MR, Mohn WW, McNagny KM, Finlay BB. Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. Embo Reports. 13: 440-7. PMID 22422004 DOI: 10.1038/embor.2012.32  0.52
2012 Antunes LC, Wang M, Andersen SK, Ferreira RB, Kappelhoff R, Han J, Borchers CH, Finlay BB. Repression of Salmonella enterica phoP expression by small molecules from physiological bile. Journal of Bacteriology. 194: 2286-96. PMID 22366421 DOI: 10.1128/JB.00104-12  0.52
2012 Axerio-Cilies P, See RH, Zoraghi R, Worral L, Lian T, Stoynov N, Jiang J, Kaur S, Jackson L, Gong H, Swayze R, Amandoron E, Kumar NS, Moreau A, Hsing M, ... ... Finlay BB, et al. Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase. Acs Chemical Biology. 7: 350-9. PMID 22066782 DOI: 10.1021/cb2003576  0.52
2012 Auweter SD, Yu HB, Arena ET, Guttman JA, Finlay BB. Oxysterol-binding protein (OSBP) enhances replication of intracellular Salmonella and binds the Salmonella SPI-2 effector SseL via its N-terminus. Microbes and Infection / Institut Pasteur. 14: 148-54. PMID 21988961 DOI: 10.1016/j.micinf.2011.09.003  0.52
2011 Zoraghi R, Worrall L, See RH, Strangman W, Popplewell WL, Gong H, Samaai T, Swayze RD, Kaur S, Vuckovic M, Finlay BB, Brunham RC, McMaster WR, Davies-Coleman MT, Strynadka NC, et al. Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities. The Journal of Biological Chemistry. 286: 44716-25. PMID 22030393 DOI: 10.1074/jbc.M111.289033  0.52
2011 Arena ET, Auweter SD, Antunes LC, Vogl AW, Han J, Guttman JA, Croxen MA, Menendez A, Covey SD, Borchers CH, Finlay BB. The deubiquitinase activity of the Salmonella pathogenicity island 2 effector, SseL, prevents accumulation of cellular lipid droplets. Infection and Immunity. 79: 4392-400. PMID 21875964 DOI: 10.1128/IAI.05478-11  0.52
2011 Shames SR, Bhavsar AP, Croxen MA, Law RJ, Mak SH, Deng W, Li Y, Bidshari R, de Hoog CL, Foster LJ, Finlay BB. The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300. Cellular Microbiology. 13: 1542-57. PMID 21812888 DOI: 10.1111/j.1462-5822.2011.01640.x  0.52
2011 Biemans-Oldehinkel E, Sal-Man N, Deng W, Foster LJ, Finlay BB. Quantitative proteomic analysis reveals formation of an EscL-EscQ-EscN type III complex in enteropathogenic Escherichia coli. Journal of Bacteriology. 193: 5514-9. PMID 21804003 DOI: 10.1128/JB.05235-11  0.52
2011 Antunes LC, Andersen SK, Menendez A, Arena ET, Han J, Ferreira RB, Borchers CH, Finlay BB. Metabolomics reveals phospholipids as important nutrient sources during Salmonella growth in bile in vitro and in vivo. Journal of Bacteriology. 193: 4719-25. PMID 21764918 DOI: 10.1128/JB.05132-11  0.52
2011 Sham HP, Shames SR, Croxen MA, Ma C, Chan JM, Khan MA, Wickham ME, Deng W, Finlay BB, Vallance BA. Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation. Infection and Immunity. 79: 3552-62. PMID 21746856 DOI: 10.1128/IAI.05033-11  0.52
2011 Ferreira RB, Gill N, Willing BP, Antunes LC, Russell SL, Croxen MA, Finlay BB. The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization. Plos One. 6: e20338. PMID 21633507 DOI: 10.1371/journal.pone.0020338  0.52
2011 Auweter SD, Bhavsar AP, de Hoog CL, Li Y, Chan YA, van der Heijden J, Lowden MJ, Coombes BK, Rogers LD, Stoynov N, Foster LJ, Finlay BB. Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partners. The Journal of Biological Chemistry. 286: 24023-35. PMID 21566117 DOI: 10.1074/jbc.M111.224600  0.52
2011 Willing BP, Antunes LC, Keeney KM, Ferreira RB, Finlay BB. Harvesting the biological potential of the human gut microbiome. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 33: 414-8. PMID 21500237 DOI: 10.1002/bies.201100030  0.52
2011 Brown NF, Coombes BK, Bishop JL, Wickham ME, Lowden MJ, Gal-Mor O, Goode DL, Boyle EC, Sanderson KL, Finlay BB. Salmonella phage ST64B encodes a member of the SseK/NleB effector family. Plos One. 6: e17824. PMID 21445262 DOI: 10.1371/journal.pone.0017824  0.52
2011 Willing BP, Russell SL, Finlay BB. Shifting the balance: antibiotic effects on host-microbiota mutualism. Nature Reviews. Microbiology. 9: 233-43. PMID 21358670 DOI: 10.1038/nrmicro2536  0.52
2011 Keeney KM, Finlay BB. Enteric pathogen exploitation of the microbiota-generated nutrient environment of the gut. Current Opinion in Microbiology. 14: 92-8. PMID 21215681 DOI: 10.1016/j.mib.2010.12.012  0.52
2011 Cherkasov A, Hsing M, Zoraghi R, Foster LJ, See RH, Stoynov N, Jiang J, Kaur S, Lian T, Jackson L, Gong H, Swayze R, Amandoron E, Hormozdiari F, Dao P, ... ... Finlay BB, et al. Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus. Journal of Proteome Research. 10: 1139-50. PMID 21166474 DOI: 10.1021/pr100918u  0.52
2010 Xie HX, Yu HB, Zheng J, Nie P, Foster LJ, Mok YK, Finlay BB, Leung KY. EseG, an effector of the type III secretion system of Edwardsiella tarda, triggers microtubule destabilization. Infection and Immunity. 78: 5011-21. PMID 20855515 DOI: 10.1128/IAI.00152-10  0.52
2010 Zoraghi R, See RH, Gong H, Lian T, Swayze R, Finlay BB, Brunham RC, McMaster WR, Reiner NE. Functional analysis, overexpression, and kinetic characterization of pyruvate kinase from methicillin-resistant Staphylococcus aureus. Biochemistry. 49: 7733-47. PMID 20707314 DOI: 10.1021/bi100780t  0.52
2010 Xicohtencatl-Cortes J, Saldaña Z, Deng W, Castañeda E, Freer E, Tarr PI, Finlay BB, Puente JL, Girón JA. Bacterial macroscopic rope-like fibers with cytopathic and adhesive properties. The Journal of Biological Chemistry. 285: 32336-42. PMID 20688909 DOI: 10.1074/jbc.M110.162248  0.64
2010 Guttman JA, Lin AE, Veiga E, Cossart P, Finlay BB. Role for CD2AP and other endocytosis-associated proteins in enteropathogenic Escherichia coli pedestal formation. Infection and Immunity. 78: 3316-22. PMID 20515931 DOI: 10.1128/IAI.00161-10  0.52
2010 Grassl GA, Faustmann M, Gill N, Zbytnuik L, Merkens H, So L, Rossi FM, McNagny KM, Finlay BB. CD34 mediates intestinal inflammation in Salmonella-infected mice. Cellular Microbiology. 12: 1562-75. PMID 20497179 DOI: 10.1111/j.1462-5822.2010.01488.x  0.52
2010 Bergstrom KS, Kissoon-Singh V, Gibson DL, Ma C, Montero M, Sham HP, Ryz N, Huang T, Velcich A, Finlay BB, Chadee K, Vallance BA. Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. Plos Pathogens. 6: e1000902. PMID 20485566 DOI: 10.1371/journal.ppat.1000902  0.52
2010 Shames SR, Deng W, Guttman JA, de Hoog CL, Li Y, Hardwidge PR, Sham HP, Vallance BA, Foster LJ, Finlay BB. The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling. Cellular Microbiology. 12: 1322-39. PMID 20374249 DOI: 10.1111/j.1462-5822.2010.01470.x  0.52
2010 Bhavsar AP, Auweter SD, Finlay BB. Proteomics as a probe of microbial pathogenesis and its molecular boundaries. Future Microbiology. 5: 253-65. PMID 20143948 DOI: 10.2217/fmb.09.114  0.52
2010 Han J, Antunes LCM, Finlay BB, Borchers CH. Metabolomics: Towards understanding host-microbe interactions Future Microbiology. 5: 153-161. PMID 20143941 DOI: 10.2217/fmb.09.132  0.52
2010 Deng W, de Hoog CL, Yu HB, Li Y, Croxen MA, Thomas NA, Puente JL, Foster LJ, Finlay BB. A comprehensive proteomic analysis of the type III secretome of Citrobacter rodentium. The Journal of Biological Chemistry. 285: 6790-800. PMID 20034934 DOI: 10.1074/jbc.M109.086603  0.52
2009 Menendez A, Arena ET, Guttman JA, Thorson L, Vallance BA, Vogl W, Finlay BB. Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever. The Journal of Infectious Diseases. 200: 1703-13. PMID 19852670 DOI: 10.1086/646608  0.52
2009 Spreter T, Yip CK, Sanowar S, André I, Kimbrough TG, Vuckovic M, Pfuetzner RA, Deng W, Yu AC, Finlay BB, Baker D, Miller SI, Strynadka NC. A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system. Nature Structural & Molecular Biology. 16: 468-76. PMID 19396170 DOI: 10.1038/nsmb.1603  0.52
2009 Guttman JA, Finlay BB. Tight junctions as targets of infectious agents. Biochimica Et Biophysica Acta. 1788: 832-41. PMID 19059200 DOI: 10.1016/j.bbamem.2008.10.028  0.52
2009 Valdez Y, Grassl GA, Guttman JA, Coburn B, Gros P, Vallance BA, Finlay BB. Nramp1 drives an accelerated inflammatory response during Salmonella-induced colitis in mice. Cellular Microbiology. 11: 351-62. PMID 19016783 DOI: 10.1111/j.1462-5822.2008.01258.x  0.52
2008 Auweter SD, Bhavsar AP, Finlay BB. Host factor reveals the intrinsic enzymatic activity of a bacterial effector. Future Microbiology. 3: 617-20. PMID 19072178 DOI: 10.2217/17460913.3.6.617  0.52
2008 Guttman JA, Finlay BB. Subcellular alterations that lead to diarrhea during bacterial pathogenesis. Trends in Microbiology. 16: 535-42. PMID 18819802 DOI: 10.1016/j.tim.2008.08.004  0.52
2008 Champion OL, Valdez Y, Thorson L, Guttman JA, Menendez A, Gaynor EC, Finlay BB. A murine intraperitoneal infection model reveals that host resistance to Campylobacter jejuni is Nramp1 dependent. Microbes and Infection / Institut Pasteur. 10: 922-7. PMID 18656410 DOI: 10.1016/j.micinf.2008.05.001  0.52
2008 Rogers LD, Kristensen AR, Boyle EC, Robinson DP, Ly RT, Finlay BB, Foster LJ. Identification of cognate host targets and specific ubiquitylation sites on the Salmonella SPI-1 effector SopB/SigD. Journal of Proteomics. 71: 97-108. PMID 18541478 DOI: 10.1016/j.jprot.2008.01.011  0.52
2008 Zarivach R, Deng W, Vuckovic M, Felise HB, Nguyen HV, Miller SI, Finlay BB, Strynadka NC. Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS. Nature. 453: 124-7. PMID 18451864 DOI: 10.1038/nature06832  0.52
2008 Bishop JL, Sly LM, Krystal G, Finlay BB. The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo. Infection and Immunity. 76: 2913-22. PMID 18426884 DOI: 10.1128/IAI.01596-07  0.52
2008 Valdez Y, Diehl GE, Vallance BA, Grassl GA, Guttman JA, Brown NF, Rosenberger CM, Littman DR, Gros P, Finlay BB. Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection. Cellular Microbiology. 10: 1646-61. PMID 18397382 DOI: 10.1111/j.1462-5822.2008.01155.x  0.52
2008 Echtenkamp F, Deng W, Wickham ME, Vazquez A, Puente JL, Thanabalasuriar A, Gruenheid S, Finlay BB, Hardwidge PR. Characterization of the NleF effector protein from attaching and effacing bacterial pathogens. Fems Microbiology Letters. 281: 98-107. PMID 18279332 DOI: 10.1111/j.1574-6968.2008.01088.x  0.52
2008 White AP, Gibson DL, Grassl GA, Kay WW, Finlay BB, Vallance BA, Surette MG. Aggregation via the red, dry, and rough morphotype is not a virulence adaptation in Salmonella enterica serovar Typhimurium. Infection and Immunity. 76: 1048-58. PMID 18195033 DOI: 10.1128/IAI.01383-07  0.52
2007 Bhavsar AP, Guttman JA, Finlay BB. Manipulation of host-cell pathways by bacterial pathogens. Nature. 449: 827-34. PMID 17943119 DOI: 10.1038/nature06247  0.52
2007 Gallant CJ, Malik S, Jabado N, Cellier M, Simkin L, Finlay BB, Graviss EA, Gros P, Musser JM, Schurr E. Reduced in vitro functional activity of human NRAMP1 (SLC11A1) allele that predisposes to increased risk of pediatric tuberculosis disease Genes and Immunity. 8: 691-698. PMID 17917676 DOI: 10.1038/sj.gene.6364435  0.52
2007 Boyle EC, Brown NF, Brumell JH, Finlay BB. Src homology domain 2 adaptors affect adherence of Salmonella enterica serovar Typhimurium to non-phagocytic cells. Microbiology (Reading, England). 153: 3517-26. PMID 17906149 DOI: 10.1099/mic.0.2007/008581-0  0.52
2007 Bakowski MA, Cirulis JT, Brown NF, Finlay BB, Brumell JH. SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion. Cellular Microbiology. 9: 2839-55. PMID 17696999 DOI: 10.1111/j.1462-5822.2007.01000.x  0.52
2007 Thomas NA, Deng W, Baker N, Puente J, Finlay BB. Hierarchical delivery of an essential host colonization factor in enteropathogenic Escherichia coli. The Journal of Biological Chemistry. 282: 29634-45. PMID 17681945 DOI: 10.1074/jbc.M706019200  0.4
2007 Kenyon WJ, Nicholson KL, Rezuchova B, Homerova D, Garcia-del Portillo F, Finlay BB, Pallen MJ, Kormanec J, Spector MP. Sigma(s)-Dependent carbon-starvation induction of pbpG (PBP 7) is required for the starvation-stress response in Salmonella enterica serovar Typhimurium. Microbiology (Reading, England). 153: 2148-58. PMID 17600059 DOI: 10.1099/mic.0.2007/005199-0  0.52
2007 Wickham ME, Brown NF, Boyle EC, Coombes BK, Finlay BB. Virulence is positively selected by transmission success between mammalian hosts. Current Biology : Cb. 17: 783-8. PMID 17442572 DOI: 10.1016/j.cub.2007.03.067  0.52
2007 Guttman JA, Kazemi P, Lin AE, Vogl AW, Finlay BB. Desmosomes are unaltered during infections by attaching and effacing pathogens. Anatomical Record (Hoboken, N.J. : 2007). 290: 199-205. PMID 17441212 DOI: 10.1002/ar.20414  0.52
2007 Mason D, Mallo GV, Terebiznik MR, Payrastre B, Finlay BB, Brumell JH, Rameh L, Grinstein S. Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. The Journal of General Physiology. 129: 267-83. PMID 17389247 DOI: 10.1085/jgp.200609656  0.52
2007 Zarivach R, Vuckovic M, Deng W, Finlay BB, Strynadka NC. Structural analysis of a prototypical ATPase from the type III secretion system. Nature Structural & Molecular Biology. 14: 131-7. PMID 17237797 DOI: 10.1038/nsmb1196  0.52
2007 Coombes BK, Lowden MJ, Bishop JL, Wickham ME, Brown NF, Duong N, Osborne S, Gal-Mor O, Finlay BB. SseL is a salmonella-specific translocated effector integrated into the SsrB-controlled salmonella pathogenicity island 2 type III secretion system. Infection and Immunity. 75: 574-80. PMID 17158898 DOI: 10.1128/IAI.00985-06  0.52
2007 Guttman JA, Samji FN, Li Y, Deng W, Lin A, Finlay BB. Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogens. Cellular Microbiology. 9: 131-41. PMID 16889624 DOI: 10.1111/j.1462-5822.2006.00773.x  0.52
2006 Goosney DL, Kujat Choy SL, Finlay BB. Salmonella and Enteropathogenic Escherichia coli Interactions with Host Cells: Signaling Pathways. Ecosal Plus. 2. PMID 26443572 DOI: 10.1128/ecosalplus.8.8.4  0.76
2006 Guttman JA, Samji FN, Li Y, Vogl AW, Finlay BB. Evidence that tight junctions are disrupted due to intimate bacterial contact and not inflammation during attaching and effacing pathogen infection in vivo. Infection and Immunity. 74: 6075-84. PMID 16954399 DOI: 10.1128/IAI.00721-06  0.52
2006 Wickham ME, Lupp C, Mascarenhas M, Vazquez A, Coombes BK, Brown NF, Coburn BA, Deng W, Puente JL, Karmali MA, Finlay BB. Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection. The Journal of Infectious Diseases. 194: 819-27. PMID 16941350 DOI: 10.1086/506620  0.52
2006 Ma C, Wickham ME, Guttman JA, Deng W, Walker J, Madsen KL, Jacobson K, Vogl WA, Finlay BB, Vallance BA. Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map). Cellular Microbiology. 8: 1669-86. PMID 16759225 DOI: 10.1111/j.1462-5822.2006.00741.x  0.52
2006 Brown NF, Wickham ME, Coombes BK, Finlay BB. Crossing the line: selection and evolution of virulence traits. Plos Pathogens. 2: e42. PMID 16733541 DOI: 10.1371/journal.ppat.0020042  0.52
2006 Khan MA, Ma C, Knodler LA, Valdez Y, Rosenberger CM, Deng W, Finlay BB, Vallance BA. Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infection and Immunity. 74: 2522-36. PMID 16622187 DOI: 10.1128/IAI.74.5.2522-2536.2006  0.56
2006 Guttman JA, Li Y, Wickham ME, Deng W, Vogl AW, Finlay BB. Attaching and effacing pathogen-induced tight junction disruption in vivo. Cellular Microbiology. 8: 634-45. PMID 16548889 DOI: 10.1111/j.1462-5822.2005.00656.x  0.52
2006 Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. Journal of Natural Products. 69: 173-7. PMID 16499312 DOI: 10.1021/np050192h  0.52
2006 See RH, Zakhartchouk AN, Petric M, Lawrence DJ, Mok CP, Hogan RJ, Rowe T, Zitzow LA, Karunakaran KP, Hitt MM, Graham FL, Prevec L, Mahony JB, Sharon C, Auperin TC, ... ... Finlay BB, et al. Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. The Journal of General Virology. 87: 641-50. PMID 16476986 DOI: 10.1099/vir.0.81579-0  0.52
2006 Martin-Orozco N, Touret N, Zaharik ML, Park E, Kopelman R, Miller S, Finlay BB, Gros P, Grinstein S. Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Molecular Biology of the Cell. 17: 498-510. PMID 16251362 DOI: 10.1091/mbc.E04-12-1096  0.52
2005 Coombes BK, Wickham ME, Lowden MJ, Brown NF, Finlay BB. Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid. Proceedings of the National Academy of Sciences of the United States of America. 102: 17460-5. PMID 16301528 DOI: 10.1073/pnas.0505401102  0.52
2005 Coombes BK, Coburn BA, Potter AA, Gomis S, Mirakhur K, Li Y, Finlay BB. Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious enterocolitis. Infection and Immunity. 73: 7161-9. PMID 16239510 DOI: 10.1128/IAI.73.11.7161-7169.2005  0.52
2005 Gauthier A, Robertson ML, Lowden M, Ibarra JA, Puente JL, Finlay BB. Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli. Antimicrobial Agents and Chemotherapy. 49: 4101-9. PMID 16189086 DOI: 10.1128/AAC.49.10.4101-4109.2005  0.52
2005 Thomas NA, Deng W, Puente JL, Frey EA, Yip CK, Strynadka NC, Finlay BB. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli. Molecular Microbiology. 57: 1762-79. PMID 16135239 DOI: 10.1111/j.1365-2958.2005.04802.x  0.52
2005 Yip CK, Kimbrough TG, Felise HB, Vuckovic M, Thomas NA, Pfuetzner RA, Frey EA, Finlay BB, Miller SI, Strynadka NC. Structural characterization of the molecular platform for type III secretion system assembly. Nature. 435: 702-7. PMID 15931226 DOI: 10.1038/nature03554  0.52
2005 Hardwidge PR, Deng W, Vallance BA, Rodriguez-Escudero I, Cid VJ, Molina M, Finlay BB. Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspG. Infection and Immunity. 73: 2586-94. PMID 15845460 DOI: 10.1128/IAI.73.5.2586-2594.2005  0.44
2005 Coombes BK, Wickham ME, Brown NF, Lemire S, Bossi L, Hsiao WW, Brinkman FS, Finlay BB. Genetic and molecular analysis of GogB, a phage-encoded type III-secreted substrate in Salmonella enterica serovar typhimurium with autonomous expression from its associated phage. Journal of Molecular Biology. 348: 817-30. PMID 15843015 DOI: 10.1016/j.jmb.2005.03.024  0.52
2005 Lupp C, Finlay BB. Intestinal microbiota. Current Biology : Cb. 15: R235-6. PMID 15823518 DOI: 10.1016/j.cub.2005.03.032  0.52
2005 Deng W, Li Y, Hardwidge PR, Frey EA, Pfuetzner RA, Lee S, Gruenheid S, Strynakda NC, Puente JL, Finlay BB. Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens. Infection and Immunity. 73: 2135-46. PMID 15784556 DOI: 10.1128/IAI.73.4.2135-2146.2005  0.52
2005 Coombes BK, Finlay BB. Insertion of the bacterial type III translocon: not your average needle stick. Trends in Microbiology. 13: 92-5. PMID 15737725 DOI: 10.1016/j.tim.2005.01.008  0.52
2005 Yip CK, Finlay BB, Strynadka NC. Structural characterization of a type III secretion system filament protein in complex with its chaperone. Nature Structural & Molecular Biology. 12: 75-81. PMID 15619638 DOI: 10.1038/nsmb879  0.52
2004 Jiang X, Rossanese OW, Brown NF, Kujat-Choy S, Galán JE, Finlay BB, Brumell JH. The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice. Molecular Microbiology. 54: 1186-98. PMID 15554961 DOI: 10.1111/j.1365-2958.2004.04344.x  0.52
2004 Coombes BK, Valdez Y, Finlay BB. Evasive maneuvers by secreted bacterial proteins to avoid innate immune responses. Current Biology : Cb. 14: R856-67. PMID 15458668 DOI: 10.1016/j.cub.2004.09.043  0.52
2004 Coombes BK, Brown NF, Valdez Y, Brumell JH, Finlay BB. Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL. The Journal of Biological Chemistry. 279: 49804-15. PMID 15383528 DOI: 10.1074/jbc.M404299200  0.52
2004 Zaharik ML, Cullen VL, Fung AM, Libby SJ, Kujat Choy SL, Coburn B, Kehres DG, Maguire ME, Fang FC, Finlay BB. The Salmonella enterica serovar typhimurium divalent cation transport systems MntH and SitABCD are essential for virulence in an Nramp1G169 murine typhoid model. Infection and Immunity. 72: 5522-5. PMID 15322058 DOI: 10.1128/IAI.72.9.5522-5525.2004  0.52
2004 Kujat Choy SL, Boyle EC, Gal-Mor O, Goode DL, Valdez Y, Vallance BA, Finlay BB. SseK1 and SseK2 are novel translocated proteins of Salmonella enterica serovar typhimurium. Infection and Immunity. 72: 5115-25. PMID 15322005 DOI: 10.1128/IAI.72.9.5115-5125.2004  0.52
2004 Pollard AJ, Currie A, Rosenberger CM, Heale JP, Finlay BB, Speert DP. Differential post-transcriptional activation of human phagocytes by different Pseudomonas aeruginosa isolates. Cellular Microbiology. 6: 639-50. PMID 15186400 DOI: 10.1111/j.1462-5822.2004.00388.x  0.52
2004 Maaser C, Housley MP, Iimura M, Smith JR, Vallance BA, Finlay BB, Schreiber JR, Varki NM, Kagnoff MF, Eckmann L. Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infection and Immunity. 72: 3315-24. PMID 15155635 DOI: 10.1128/IAI.72.6.3315-3324.2004  0.52
2004 Harrison RE, Brumell JH, Khandani A, Bucci C, Scott CC, Jiang X, Finlay BB, Grinstein S. Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Molecular Biology of the Cell. 15: 3146-54. PMID 15121880 DOI: 10.1091/mbc.E04-02-0092  0.52
2004 Deng W, Puente JL, Gruenheid S, Li Y, Vallance BA, Vázquez A, Barba J, Ibarra JA, O'Donnell P, Metalnikov P, Ashman K, Lee S, Goode D, Pawson T, Finlay BB. Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proceedings of the National Academy of Sciences of the United States of America. 101: 3597-602. PMID 14988506 DOI: 10.1073/pnas.0400326101  0.52
2004 Hardwidge PR, Rodriguez-Escudero I, Goode D, Donohoe S, Eng J, Goodlett DR, Aebersold R, Finlay BB. Proteomic analysis of the intestinal epithelial cell response to enteropathogenic Escherichia coli. The Journal of Biological Chemistry. 279: 20127-36. PMID 14988394 DOI: 10.1074/jbc.M401228200  0.52
2004 Rosenberger CM, Gallo RL, Finlay BB. Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication. Proceedings of the National Academy of Sciences of the United States of America. 101: 2422-7. PMID 14983025 DOI: 10.1073/pnas.0304455101  0.56
2004 Gruenheid S, Sekirov I, Thomas NA, Deng W, O'Donnell P, Goode D, Li Y, Frey EA, Brown NF, Metalnikov P, Pawson T, Ashman K, Finlay BB. Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7. Molecular Microbiology. 51: 1233-49. PMID 14982621 DOI: 10.1046/j.1365-2958.2003.03911.x  0.52
2004 Zaharik ML, Finlay BB. Mn2+ and bacterial pathogenesis. Frontiers in Bioscience : a Journal and Virtual Library. 9: 1035-42. PMID 14977526  0.88
2003 Gauthier A, Finlay BB. Translocated intimin receptor and its chaperone interact with ATPase of the type III secretion apparatus of enteropathogenic Escherichia coli. Journal of Bacteriology. 185: 6747-55. PMID 14617638  0.84
2003 Coombes BK, Brown NF, Kujat-Choy S, Vallance BA, Finlay BB. SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells. Microbes and Infection / Institut Pasteur. 5: 561-70. PMID 12787732 DOI: 10.1016/S1286-4579(03)00094-7  0.52
2003 Gauthier A, Puente JL, Finlay BB. Secretin of the enteropathogenic Escherichia coli type III secretion system requires components of the type III apparatus for assembly and localization. Infection and Immunity. 71: 3310-9. PMID 12761113  0.84
2003 Gauthier A, Thomas NA, Finlay BB. Bacterial injection machines. The Journal of Biological Chemistry. 278: 25273-6. PMID 12759358 DOI: 10.1074/jbc.R300012200  0.84
2003 Rosenberger CM, Finlay BB. Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens. Nature Reviews. Molecular Cell Biology. 4: 385-96. PMID 12728272 DOI: 10.1038/nrm1104  0.56
2003 Gruenheid S, Finlay BB. Microbial pathogenesis and cytoskeletal function. Nature. 422: 775-81. PMID 12700772 DOI: 10.1038/nature01603  0.52
2003 Kurz CL, Chauvet S, Andrès E, Aurouze M, Vallet I, Michel GPF, Uh M, Celli J, Filloux A, De Bentzmann S, Steinmetz I, Hoffmann JA, Finlay BB, Gorvel JP, Ferrandon D, et al. Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening Embo Journal. 22: 1451-1460. PMID 12660152 DOI: 10.1093/emboj/cdg159  0.52
2003 Brumell JH, Kujat-Choy S, Brown NF, Vallance BA, Knodler LA, Finlay BB. SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells. Traffic (Copenhagen, Denmark). 4: 36-48. PMID 12535274 DOI: 10.1034/j.1600-0854.2003.40106.x  0.52
2002 Horne C, Vallance BA, Deng W, Finlay BB. Current progress in enteropathogenic and enterohemorrhagic Escherichia coli vaccines Expert Review of Vaccines. 1: 483-493. PMID 12901587 DOI: 10.1586/14760584.1.4.483  0.52
2002 Zaharik ML, Vallance BA, Puente JL, Gros P, Finlay BB. Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes. Proceedings of the National Academy of Sciences of the United States of America. 99: 15705-10. PMID 12441401 DOI: 10.1073/pnas.252415599  0.88
2002 Linington RG, Robertson M, Gauthier A, Finlay BB, van Soest R, Andersen RJ. Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia. Organic Letters. 4: 4089-92. PMID 12423093 DOI: 10.1021/ol0268337  0.52
2002 Terebiznik MR, Vieira OV, Marcus SL, Slade A, Yip CM, Trimble WS, Meyer T, Finlay BB, Grinstein S. Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nature Cell Biology. 4: 766-73. PMID 12360287 DOI: 10.1038/ncb854  0.52
2002 Brinkman FS, Blanchard JL, Cherkasov A, Av-Gay Y, Brunham RC, Fernandez RC, Finlay BB, Otto SP, Ouellette BF, Keeling PJ, Rose AM, Hancock RE, Jones SJ, Greberg H. Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast. Genome Research. 12: 1159-67. PMID 12176923 DOI: 10.1101/gr.341802  0.52
2002 Brumell JH, Tang P, Zaharik ML, Finlay BB. Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infection and Immunity. 70: 3264-70. PMID 12011022 DOI: 10.1128/IAI.70.6.3264-3270.2002  0.52
2002 Brumell JH, Goosney DL, Finlay BB. SifA, a type III secreted effector of Salmonella typhimurium, directs Salmonella-induced filament (Sif) formation along microtubules. Traffic (Copenhagen, Denmark). 3: 407-15. PMID 12010459 DOI: 10.1034/j.1600-0854.2002.30604.x  0.52
2002 Zaharik ML, Gruenheid S, Perrin AJ, Finlay BB. Delivery of dangerous goods: type III secretion in enteric pathogens. International Journal of Medical Microbiology : Ijmm. 291: 593-603. PMID 12008913 DOI: 10.1078/1438-4221-00179  0.52
2002 Knodler LA, Celli J, Hardt WD, Vallance BA, Yip C, Finlay BB. Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems. Molecular Microbiology. 43: 1089-103. PMID 11918798 DOI: 10.1046/j.1365-2958.2002.02820.x  0.52
2002 Steele-Mortimer O, Brumell JH, Knodler LA, Méresse S, Lopez A, Finlay BB. The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells. Cellular Microbiology. 4: 43-54. PMID 11856172 DOI: 10.1046/j.1462-5822.2002.00170.x  0.52
2002 Rosenberger CM, Finlay BB. Macrophages inhibit Salmonella typhimurium replication through MEK/ERK kinase and phagocyte NADPH oxidase activities. The Journal of Biological Chemistry. 277: 18753-62. PMID 11821396 DOI: 10.1074/jbc.M110649200  0.56
2002 Brumell JH, Perrin AJ, Goosney DL, Finlay BB. Microbial pathogenesis: New niches for Salmonella Current Biology. 12: R15-R17. PMID 11790317 DOI: 10.1016/S0960-9822(01)00640-6  0.52
2001 Rosenberger CM, Pollard AJ, Finlay BB. Gene array technology to determine host responses to Salmonella. Microbes and Infection / Institut Pasteur. 3: 1353-60. PMID 11755425  0.56
2001 DeVinney R, Puente JL, Gauthier A, Goosney D, Finlay BB. Enterohaemorrhagic and enteropathogenic Escherichia coli use a different Tir-based mechanism for pedestal formation. Molecular Microbiology. 41: 1445-58. PMID 11580847 DOI: 10.1046/J.1365-2958.2001.02617.X  0.84
2001 Brumell JH, Tang P, Mills SD, Finlay BB. Characterization of Salmonella-induced filaments (Sifs) reveals a delayed interaction between Salmonella-containing vacuoles and late endocytic compartments Traffic. 2: 643-653. PMID 11555418 DOI: 10.1034/j.1600-0854.2001.20907.x  0.52
2001 de Grado M, Rosenberger CM, Gauthier A, Vallance BA, Finlay BB. Enteropathogenic Escherichia coli infection induces expression of the early growth response factor by activating mitogen-activated protein kinase cascades in epithelial cells. Infection and Immunity. 69: 6217-24. PMID 11553563 DOI: 10.1128/IAI.69.10.6217-6224.2001  0.84
2001 Gruenheid S, DeVinney R, Bladt F, Goosney D, Gelkop S, Gish GD, Pawson T, Finlay BB. Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells Nature Cell Biology. 3: 856-859. PMID 11533668 DOI: 10.1038/ncb0901-856  0.52
2001 Gauthier A, Finlay BB. Bacterial pathogenesis: the answer to virulence is in the pore. Current Biology : Cb. 11: R264-7. PMID 11413015  0.84
2001 Marcus SL, Wenk MR, Steele-Mortimer O, Finlay BB. A synaptojanin-homologous region of Salmonella typhimurium SigD is essential for inositol phosphatase activity and Akt activation. Febs Letters. 494: 201-7. PMID 11311241 DOI: 10.1016/S0014-5793(01)02356-0  0.4
2001 Goosney DL, DeVinney R, Finlay BB. Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals. Infection and Immunity. 69: 3315-22. PMID 11292754 DOI: 10.1128/IAI.69.5.3315-3322.2001  0.76
2001 Brumell JH, Rosenberger CM, Gotto GT, Marcus SL, Finlay BB. SifA permits survival and replication of Salmonella typhimurium in murine macrophages. Cellular Microbiology. 3: 75-84. PMID 11207622 DOI: 10.1046/j.1462-5822.2001.00087.x  0.52
2001 Coppolino MG, Kong C, Mohtashami M, Schreiber AD, Brumell JH, Finlay BB, Grinstein S, Trimble WS. Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. The Journal of Biological Chemistry. 276: 4772-80. PMID 11092884 DOI: 10.1074/jbc.M007792200  0.52
2000 Rosenberger CM, Brumell JH, Finlay BB. Microbial pathogenesis: lipid rafts as pathogen portals. Current Biology : Cb. 10: R823-5. PMID 11102822 DOI: 10.1016/S0960-9822(00)00788-0  0.52
2000 Goosney DL, Gruenheid S, Finlay BB. Gut feelings: Enteropathogenic E. coli (EPEC) interactions with the host Annual Review of Cell and Developmental Biology. 16: 173-189. PMID 11031234 DOI: 10.1146/annurev.cellbio.16.1.173  0.52
2000 Steele-Mortimer O, Knodler LA, Marcus SL, Scheid MP, Goh B, Pfeifer CG, Duronio V, Finlay BB. Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD. The Journal of Biological Chemistry. 275: 37718-24. PMID 10978351 DOI: 10.1074/jbc.M008187200  0.4
2000 Scott MG, Rosenberger CM, Gold MR, Finlay BB, Hancock RE. An alpha-helical cationic antimicrobial peptide selectively modulates macrophage responses to lipopolysaccharide and directly alters macrophage gene expression. Journal of Immunology (Baltimore, Md. : 1950). 165: 3358-65. PMID 10975854  0.56
2000 Steele-Mortimer O, St-Louis M, Olivier M, Finlay BB. Vacuole Acidification is not required for survival of Salmonella enterica serovar Typhimurium within cultured macrophages and epithelial cells Infection and Immunity. 68: 5401-5404. PMID 10948170 DOI: 10.1128/IAI.68.9.5401-5404.2000  0.52
2000 Finlay BB, Brumell JH. Salmonella interactions with host cells: In vitro to in vivo Philosophical Transactions of the Royal Society B: Biological Sciences. 355: 623-631. PMID 10874735  0.52
2000 Goosney DL, DeVinney R, Pfuetzner RA, Frey EA, Strynadka NC, Finlay BB. Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin. Current Biology : Cb. 10: 735-8. PMID 10873808  0.76
2000 Gauthier A, de Grado M, Finlay BB. Mechanical fractionation reveals structural requirements for enteropathogenic Escherichia coli Tir insertion into host membranes. Infection and Immunity. 68: 4344-8. PMID 10858257  0.84
2000 Kehres DG, Zaharik ML, Finlay BB, Maguire ME. The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen. Molecular Microbiology. 36: 1085-100. PMID 10844693  0.88
2000 Brumell JH, Marcus SL, Finlay BB. N-terminal conservation of putative type III secreted effectors of Salmonella typhimurium. Molecular Microbiology. 36: 773-4. PMID 10844665 DOI: 10.1046/j.1365-2958.2000.01878.x  0.52
2000 Rosenberger CM, Scott MG, Gold MR, Hancock RE, Finlay BB. Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression. Journal of Immunology (Baltimore, Md. : 1950). 164: 5894-904. PMID 10820271  0.56
2000 Tacket CO, Sztein MB, Losonsky G, Abe A, Finlay BB, McNamara BP, Fantry GT, James SP, Nataro JP, Levine MM, Donnenberg MS. Role of EspB in experimental human enteropathogenic Escherichia coli infection Infection and Immunity. 68: 3689-3695. PMID 10816529 DOI: 10.1128/IAI.68.6.3689-3695.2000  0.52
2000 Marcus SL, Brumell JH, Pfeifer CG, Finlay BB. Salmonella pathogenicity islands: big virulence in small packages. Microbes and Infection / Institut Pasteur. 2: 145-56. PMID 10742687 DOI: 10.1016/S1286-4579(00)00273-2  0.52
1999 de Grado M, Abe A, Gauthier A, Steele-Mortimer O, DeVinney R, Finlay BB. Identification of the intimin-binding domain of Tir of enteropathogenic Escherichia coli. Cellular Microbiology. 1: 7-17. PMID 11207537  0.84
1999 Kalman D, Weiner OD, Goosney DL, Sedat JW, Finlay BB, Abo A, Bishop JM. Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals. Nature Cell Biology. 1: 389-91. PMID 10559969 DOI: 10.1038/14087  0.52
1999 Pfeifer CG, Marcus SL, Steele-Mortimer O, Knodler LA, Finlay BB. Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells. Infection and Immunity. 67: 5690-8. PMID 10531217 DOI: 10.1128/IAI.67.11.5690-5698.1999  0.4
1999 DeVinney R, Gauthier A, Abe A, Finlay BB. Enteropathogenic Escherichia coli: a pathogen that inserts its own receptor into host cells. Cellular and Molecular Life Sciences : Cmls. 55: 961-76. PMID 10412374  0.84
1999 Brumell JH, Steele-Mortimer O, Finlay BB. Bacterial invasion: Force feeding by Salmonella Current Biology. 9. PMID 10226015 DOI: 10.1016/S0960-9822(99)80178-X  0.52
1999 Govoni G, Canonne-Hergaux F, Pfeifer CG, Marcus SL, Mills SD, Hackam DJ, Grinstein S, Malo D, Finlay BB, Gros P. Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7. Infection and Immunity. 67: 2225-32. PMID 10225878  0.52
1999 Goosney DL, Knoechel DG, Finlay BB. Enteropathogenic E. coli, Salmonella, and Shigella: masters of host cell cytoskeletal exploitation. Emerging Infectious Diseases. 5: 216-23. PMID 10221873 DOI: 10.3201/eid0502.990205  0.76
1999 Goosney DL, de Grado M, Finlay BB. Putting E. coli on a pedestal: a unique system to study signal transduction and the actin cytoskeleton. Trends in Cell Biology. 9: 11-4. PMID 10087611  0.76
1999 Goosney DL, Celli J, Kenny B, Finlay BB. Enteropathogenic Escherichia coli inhibits phagocytosis. Infection and Immunity. 67: 490-5. PMID 9916050  0.76
1998 Gauthier A, Finlay BB. Protein translocation: delivering virulence into the host cell. Current Biology : Cb. 8: R768-70. PMID 9799724  0.84
1998 Mills SD, Ruschkowski SR, Stein MA, Finlay BB. Trafficking of porin-deficient Salmonella typhimurium mutants inside HeLa cells: ompR and envZ mutants are defective for the formation of Salmonella-induced filaments Infection and Immunity. 66: 1806-1811. PMID 9529120 DOI: 10.1128/IAI.66.4.1806-1811.1998  0.52
1997 Wilson DR, Finlay BB. The 'Asx-Pro turn' as a local structural motif stabilized by alternative patterns of hydrogen bonds and a consensus-derived model of the sequence Asn-Pro-Asn Protein Engineering. 10: 519-529. PMID 9215570 DOI: 10.1093/PROTEIN/10.5.519  0.52
1997 Donnenberg MS, Kaper JB, Finlay BB. Interactions between enteropathogenic Escherichia coli and host epithelial cells Trends in Microbiology. 5: 109-114. PMID 9080609 DOI: 10.1016/S0966-842X(97)01000-7  0.52
1997 Garcia-del Portillo F, Stein MA, Finlay BB. Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell Infection and Immunity. 65: 24-34. PMID 8975888 DOI: 10.1128/IAI.65.1.24-34.1997  0.52
1996 Stein M, Kenny B, Stein MA, Finlay BB. Characterization of EspC, a 110-kilodalton protein secreted by enteropathogenic Escherichia coli which is homologous to members of the immunoglobulin A protease-like family of secreted proteins Journal of Bacteriology. 178: 6546-6554. PMID 8932311 DOI: 10.1128/JB.178.22.6546-6554.1996  0.52
1996 Stein MA, Mathers DA, Yan H, Baimbridge KG, Finlay BB. Enteropathogenic Escherichia coli markedly decreases the resting membrane potential of Caco-2 and HeLa human epithelial cells Infection and Immunity. 64: 4820-4825. PMID 8890244 DOI: 10.1128/iai.64.11.4820-4825.1996  0.52
1996 Stein MA, Leung KY, Zwick M, Garcia-del Portillo F, Finlay BB. Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells Molecular Microbiology. 20: 151-164. PMID 8861213 DOI: 10.1111/j.1365-2958.1996.tb02497.x  0.52
1996 Kenny B, Lai LC, Finlay BB, Donnenberg MS. EspA, a protein secreted by enteropathogenic Escherichia coli, is required to induce signals in epithelial cells. Molecular Microbiology. 20: 313-23. PMID 8733230  0.52
1994 Stein MA, Mills SD, Finlay BB. Salmonella: Now you see it, now you don't Bioessays. 16: 537-538. PMID 8086001 DOI: 10.1002/bies.950160805  0.52
1994 Foubister V, Rosenshine I, Donnenberg MS, Finlay BB. The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells Infection and Immunity. 62: 3038-3040. PMID 8005695  0.52
1993 Canil C, Rosenshine I, Ruschkowski S, Donnenberg MS, Kaper JB, Finlay BB. Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers Infection and Immunity. 61: 2755-2762. PMID 8514377  0.52
1993 Garcia-Del Portillo F, Zwick MB, Leung KY, Finlay BB. Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 90: 10544-10548. PMID 8248143 DOI: 10.1073/PNAS.90.22.10544  0.52
1992 Garcia-del Portillo F, Foster JW, Maguire ME, Finlay BB. Characterization of the micro-environment of Salmonella typhimurium-containing vacuoles within MDCK epithelial cells. Molecular Microbiology. 6: 3289-97. PMID 1484485 DOI: 10.1111/j.1365-2958.1992.tb02197.x  0.32
1992 Leung KY, Ruschkowski SR, Finlay BB. Isolation and characterization of the aadA aminoglycoside‐resistance gene from Salmonella choleraesuis Molecular Microbiology. 6: 2453-2460. PMID 1406282 DOI: 10.1111/j.1365-2958.1992.tb01421.x  0.52
1991 Leung KY, Finlay BB. Intracellular replication is essential for the virulence of Salmonella typhimurium Proceedings of the National Academy of Sciences of the United States of America. 88: 11470-11474. PMID 1763061 DOI: 10.1073/PNAS.88.24.11470  0.52
1986 Lobe CG, Finlay BB, Paranchych W, Paetkau VH, Bleackley RC. Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes Science. 232: 858-861. PMID 3518058 DOI: 10.1126/science.3518058  0.52
1986 Worobec EA, Frost LS, Pieroni P, Armstrong GD, Hodges RS, Parker JM, Finlay BB, Paranchych W. Location of the antigenic determinants of conjugative F-like pili Journal of Bacteriology. 167: 660-665. PMID 2426247  0.52
1983 Frost LS, Armstrong GD, Finlay BB, Edwards BF, Paranchych W. N-terminal amino acid sequencing of EDP208 conjugative pili Journal of Bacteriology. 153: 950-954. PMID 6130062  0.52
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