Bruce M. McManus - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Pathology, Rehabilitation and Therapy, Cell Biology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sellers SL, Hensey M, Cartlidge TRG, Turner CT, Lau K, Lai A, Salcudean H, Sathananthan J, McManus BM, Granville DJ, Payne GW, Pibarot P, Webb JG, Newby DE, Blanke P, et al. Tricuspid Valve-in-Valve and Bioprosthetic Surgical Tricuspid and Pulmonic Valve Degeneration: Lessons From Imaging and Histopathology. Jacc. Cardiovascular Imaging. PMID 32739371 DOI: 10.1016/J.Jcmg.2020.06.008  0.541
2020 Aguiar JA, Tremblay BJ, Mansfield MJ, Woody O, Lobb B, Banerjee A, Chandiramohan A, Tiessen N, Cao Q, Dvorkin-Gheva A, Revill S, Miller MS, Carlsten C, Organ L, Joseph C, ... ... McManus BM, et al. Gene expression and protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue. The European Respiratory Journal. PMID 32675206 DOI: 10.1183/13993003.01123-2020  0.319
2019 Hanson PJ, Hossain AR, Qiu Y, Zhang HM, Zhao G, Li C, Lin V, Sulaimon S, Vlok M, Fung G, Chen VH, Jan E, McManus BM, Granville DJ, Yang D. Cleavage and Sub-Cellular Redistribution of Nuclear Pore Protein 98 by Coxsackievirus B3 Protease 2A Impairs Cardioprotection. Frontiers in Cellular and Infection Microbiology. 9: 265. PMID 31396490 DOI: 10.3389/Fcimb.2019.00265  0.64
2019 Sellers S, Cartlidge T, Hensey M, Turner C, Lai A, Lau K, Sathananthan J, Blanke P, Granville D, McManus B, Webb J, Newby D, Dweck M, Leipsic J. TCT-96 Tricuspid Valve-in-Valve and Bioprosthetic Surgical Tricuspid and Pulmonic Valve Degeneration: Lessons From Imaging and Histopathology Journal of the American College of Cardiology. 74. DOI: 10.1016/J.Jacc.2019.08.139  0.54
2017 Shen Y, Russo V, Zeglinski MR, Sellers SL, Wu Z, Oram C, Santacruz S, Merkulova Y, Turner C, Tauh K, Zhao H, Bozin T, Bohunek L, Zeng H, Seidman MA, ... ... McManus BM, et al. Recombinant Decorin Fusion Protein Attenuates Murine Abdominal Aortic Aneurysm Formation and Rupture. Scientific Reports. 7: 15857. PMID 29158532 DOI: 10.1038/S41598-017-16194-8  0.564
2017 Sukma Dewi I, Celik S, Karlsson A, Hollander Z, Lam K, McManus JW, Tebbutt S, Ng R, Keown P, McMaster R, McManus B, Öhman J, Gidlöf O. Exosomal miR-142-3p is increased during cardiac allograft rejection and augments vascular permeability through down-regulation of endothelial RAB11FIP2 expression. Cardiovascular Research. PMID 28073833 DOI: 10.1093/Cvr/Cvw244  0.341
2015 Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha SA, Parkinson LG, Zhao H, Westendorf K, Bohunek L, Bozin T, Hsu I, Ang LS, Williams SJ, Bleackley RC, Eriksson JE, ... ... McManus BM, et al. Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis. The American Journal of Pathology. PMID 26610869 DOI: 10.1016/J.Ajpath.2015.09.010  0.564
2015 Garmaroudi FS, Marchant D, Hendry R, Luo H, Yang D, Ye X, Shi J, McManus BM. Coxsackievirus B3 replication and pathogenesis. Future Microbiology. 10: 629-53. PMID 25865198 DOI: 10.2217/Fmb.15.5  0.361
2014 Keire PA, Bressler SL, Lemire JM, Edris B, Rubin BP, Rahmani M, McManus BM, van de Rijn M, Wight TN. A role for versican in the development of leiomyosarcoma. The Journal of Biological Chemistry. 289: 34089-103. PMID 25320080 DOI: 10.1074/Jbc.M114.607168  0.319
2014 Marchant DJ, Bellac CL, Moraes TJ, Wadsworth SJ, Dufour A, Butler GS, Bilawchuk LM, Hendry RG, Robertson AG, Cheung CT, Ng J, Ang L, Luo Z, Heilbron K, Norris MJ, ... ... McManus BM, et al. A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity. Nature Medicine. 20: 493-502. PMID 24784232 DOI: 10.1038/Nm.3508  0.581
2014 Shannon CP, Balshaw R, Ng RT, Wilson-McManus JE, Keown P, McMaster R, McManus BM, Landsberg D, Isbel NM, Knoll G, Tebbutt SJ. Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection. Plos One. 9: e95224. PMID 24733377 DOI: 10.1371/Journal.Pone.0095224  0.305
2014 Yanagawa B, Algarni KD, Singh SK, Deb S, Vincent J, Elituv R, Desai ND, Rajamani K, McManus BM, Liu PP, Cohen EA, Radhakrishnan S, Dubbin JD, Schwartz L, Fremes SE. Clinical, biochemical, and genetic predictors of coronary artery bypass graft failure. The Journal of Thoracic and Cardiovascular Surgery. 148: 515-520.e2. PMID 24332189 DOI: 10.1016/J.Jtcvs.2013.10.011  0.502
2013 Hiebert PR, Boivin WA, Zhao H, McManus BM, Granville DJ. Perforin and granzyme B have separate and distinct roles during atherosclerotic plaque development in apolipoprotein E knockout mice. Plos One. 8: e78939. PMID 24205352 DOI: 10.1371/Journal.Pone.0078939  0.589
2013 Jensen KJ, Garmaroudi FS, Zhang J, Lin J, Boroomand S, Zhang M, Luo Z, Yang D, Luo H, McManus BM, Janes KA. An ERK-p38 subnetwork coordinates host cell apoptosis and necrosis during coxsackievirus B3 infection. Cell Host & Microbe. 13: 67-76. PMID 23332156 DOI: 10.1016/J.Chom.2012.11.009  0.375
2013 Paylor B, Fernandes J, McManus B, Rossi F. Tissue-resident Sca1+ PDGFRα+ mesenchymal progenitors are the cellular source of fibrofatty infiltration in arrhythmogenic cardiomyopathy F1000research. 2. DOI: 10.12688/F1000Research.2-141.V1  0.328
2012 Marchant DJ, Boyd JH, Lin DC, Granville DJ, Garmaroudi FS, McManus BM. Inflammation in myocardial diseases. Circulation Research. 110: 126-44. PMID 22223210 DOI: 10.1161/Circresaha.111.243170  0.578
2012 Carthy JM, Luo Z, McManus BM. WNT3A induces a contractile and secretory phenotype in cultured vascular smooth muscle cells that is associated with increased gap junction communication. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 246-55. PMID 22105568 DOI: 10.1038/Labinvest.2011.164  0.306
2012 Wong J, Zhang J, Yanagawa B, Luo Z, Yang X, Chang J, McManus B, Luo H. Cleavage of serum response factor mediated by enteroviral protease 2A contributes to impaired cardiac function. Cell Research. 22: 360-71. PMID 21769134 DOI: 10.1038/Cr.2011.114  0.57
2011 Ang LS, Boivin WA, Williams SJ, Zhao H, Abraham T, Carmine-Simmen K, McManus BM, Bleackley RC, Granville DJ. Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm. Cell Death & Disease. 2: e209. PMID 21900960 DOI: 10.1038/Cddis.2011.88  0.597
2010 Marchant D, Singhera GK, Utokaparch S, Hackett TL, Boyd JH, Luo Z, Si X, Dorscheid DR, McManus BM, Hegele RG. Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism. Journal of Virology. 84: 11359-73. PMID 20702616 DOI: 10.1128/Jvi.00804-10  0.329
2010 Marchant DJ, McManus BM. Regulating viral myocarditis: allografted regulatory T cells decrease immune infiltration and viral load. Circulation. 121: 2609-11. PMID 20529996 DOI: 10.1161/Circulationaha.110.960054  0.341
2010 Chamberlain CM, Ang LS, Boivin WA, Cooper DM, Williams SJ, Zhao H, Hendel A, Folkesson M, Swedenborg J, Allard MF, McManus BM, Granville DJ. Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm. The American Journal of Pathology. 176: 1038-49. PMID 20035050 DOI: 10.2353/Ajpath.2010.090700  0.58
2010 Sall A, Zhang HM, Qiu D, Liu Z, Yuan J, Liu Z, Lim T, Ye X, Marchant D, McManus B, Yang D. Pro-apoptotic activity of mBNIP-21 depends on its BNIP-2 and Cdc42GAP homology (BCH) domain and is enhanced by coxsackievirus B3 infection. Cellular Microbiology. 12: 599-614. PMID 19951366 DOI: 10.1111/J.1462-5822.2009.01416.X  0.334
2010 Rezai N, Deisher TA, Heine HL, Wang X, Corbel SY, Leung J, Kerjner A, Rossi FM, Podor TJ, McManus BM. Effects of granulocyte-colony stimulating factor on bone marrow-derived progenitor cells in murine cardiac transplantation. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 19: 36-47. PMID 19144547 DOI: 10.1016/J.Carpath.2008.10.007  0.315
2009 Wong BW, Rahmani M, Luo Z, Yanagawa B, Wong D, Luo H, McManus BM. Vascular endothelial growth factor increases human cardiac microvascular endothelial cell permeability to low-density lipoproteins. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 28: 950-7. PMID 19716049 DOI: 10.1016/J.Healun.2009.05.005  0.529
2009 Marchant D, Sall A, Si X, Abraham T, Wu W, Luo Z, Petersen T, Hegele RG, McManus BM. ERK MAP kinase-activated Arf6 trafficking directs coxsackievirus type B3 into an unproductive compartment during virus host-cell entry. The Journal of General Virology. 90: 854-62. PMID 19264606 DOI: 10.1099/Vir.0.005868-0  0.359
2009 Marchant D, Dou Y, Luo H, Garmaroudi FS, McDonough JE, Si X, Walker E, Luo Z, Arner A, Hegele RG, Laher I, McManus BM. Bosentan enhances viral load via endothelin-1 receptor type-A-mediated p38 mitogen-activated protein kinase activation while improving cardiac function during coxsackievirus-induced myocarditis. Circulation Research. 104: 813-21. PMID 19213955 DOI: 10.1161/Circresaha.108.191171  0.312
2009 Yuan J, Liu Z, Lim T, Zhang H, He J, Walker E, Shier C, Wang Y, Su Y, Sall A, McManus B, Yang D. CXCL10 inhibits viral replication through recruitment of natural killer cells in coxsackievirus B3-induced myocarditis. Circulation Research. 104: 628-38. PMID 19168435 DOI: 10.1161/Circresaha.108.192179  0.398
2008 Wong J, Zhang J, Si X, Gao G, Mao I, McManus BM, Luo H. Autophagosome supports coxsackievirus B3 replication in host cells. Journal of Virology. 82: 9143-53. PMID 18596087 DOI: 10.1128/Jvi.00641-08  0.376
2008 Hunter AL, Kerjner A, Mueller KJ, McManus BM, Granville DJ. Cytochrome p450 2C enzymes contribute to peritransplant ischemic injury and cardiac allograft vasculopathy. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 1631-8. PMID 18557730 DOI: 10.1111/J.1600-6143.2008.02296.X  0.592
2008 Gao G, Zhang J, Si X, Wong J, Cheung C, McManus B, Luo H. Proteasome inhibition attenuates coxsackievirus-induced myocardial damage in mice. American Journal of Physiology. Heart and Circulatory Physiology. 295: H401-8. PMID 18515649 DOI: 10.1152/Ajpheart.00292.2008  0.356
2008 Marchant D, Si X, Luo H, McManus B, Yang D. The impact of CVB3 infection on host cell biology Current Topics in Microbiology and Immunology. 323: 177-198. PMID 18357770 DOI: 10.1007/978-3-540-75546-3_8  0.367
2008 Cheung C, Marchant D, Walker EK, Luo Z, Zhang J, Yanagawa B, Rahmani M, Cox J, Overall C, Senior RM, Luo H, McManus BM. Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice. Circulation. 117: 1574-82. PMID 18332263 DOI: 10.1161/Circulationaha.107.733238  0.548
2008 Esfandiarei M, McManus BM. Molecular biology and pathogenesis of viral myocarditis. Annual Review of Pathology. 3: 127-55. PMID 18039131 DOI: 10.1146/Annurev.Pathmechdis.3.121806.151534  0.331
2008 Esfandiarei M, Boroomand S, Suarez A, Si X, Rahmani M, McManus B. Coxsackievirus B3 activates nuclear factor kappa B transcription factor via a phosphatidylinositol-3 kinase/protein kinase B-dependent pathway to improve host cell viability. Cellular Microbiology. 9: 2358-71. PMID 17848167 DOI: 10.1111/J.1462-5822.2007.00964.X  0.381
2008 Marchant D, Cheung C, Walker EK, Luo H, Luo Z, Zhang J, Yanagawa B, Rahmani M, McManus BM, Cox J, Overall C, Senior RM. Response to Letter Regarding Article, “Ablation of Matrix Metalloproteinase-9 Increases Severity of Viral Myocarditis in Mice” Circulation. 118. DOI: 10.1161/Circulationaha.108.794024  0.524
2008 Yanagawa B, Cheung C, McManus B, Yang D, Spiller O. Complement reduces virus replication and myocardial injury in acute Coxsackie virus B3-induced myocarditis Molecular Immunology. 45: 4164-4165. DOI: 10.1016/J.Molimm.2008.08.208  0.532
2007 Cheung CT, Deisher TA, Luo H, Yanagawa B, Bonigut S, Samra A, Zhao H, Walker EK, McManus BM. Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 651-61. PMID 17468777 DOI: 10.1038/Labinvest.3700563  0.57
2007 Si X, Wang Y, Wong J, Zhang J, McManus BM, Luo H. Dysregulation of the ubiquitin-proteasome system by curcumin suppresses coxsackievirus B3 replication. Journal of Virology. 81: 3142-50. PMID 17229707 DOI: 10.1128/Jvi.02028-06  0.378
2007 Hunter A, Kerjner A, Mueller K, McManus B, Granville D. 149: Cytochrome P450 (CYP) 2C contributes to cardiac allograft vasculopathy The Journal of Heart and Lung Transplantation. 26: S113. DOI: 10.1016/J.Healun.2006.11.165  0.563
2006 Rahmani M, Cruz RP, Granville DJ, McManus BM. Allograft vasculopathy versus atherosclerosis. Circulation Research. 99: 801-15. PMID 17038650 DOI: 10.1161/01.Res.0000246086.93555.F3  0.607
2006 Esfandiarei M, Suarez A, Amaral A, Si X, Rahmani M, Dedhar S, McManus BM. Novel role for integrin-linked kinase in modulation of coxsackievirus B3 replication and virus-induced cardiomyocyte injury. Circulation Research. 99: 354-61. PMID 16840719 DOI: 10.1161/01.Res.0000237022.72726.01  0.388
2006 Cheung C, Luo H, Yanagawa B, Leong HS, Samarasekera D, Lai JC, Suarez A, Zhang J, McManus BM. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in coxsackievirus-induced myocarditis. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 15: 63-74. PMID 16533694 DOI: 10.1016/J.Carpath.2005.11.008  0.517
2006 Wong J, Zhang J, Gao G, Esfandiarei M, Si X, Wang Y, Yanagawa B, Suarez A, McManus B, Luo H. Liposome-mediated transient transfection reduces cholesterol-dependent coxsackievirus infectivity. Journal of Virological Methods. 133: 211-8. PMID 16375979 DOI: 10.1016/J.Jviromet.2005.11.013  0.559
2006 Cruz RP, Zhao H, Choy JC, McManus BM, Granville DJ. Granzyme B in age-associated disorders: Unique and exciting characteristics discovered in a double knockout model Vascular Pharmacology. 45: e91. DOI: 10.1016/J.Vph.2006.08.257  0.535
2006 Cruz RP, Zhao H, McManus BM, Choy J, Granville DJ. Granzyme B is expressed in macrophage foam cells and plays a key role in atherosclerosis Vascular Pharmacology. 45: 191-192. DOI: 10.1016/J.Vph.2006.08.047  0.576
2005 Si X, Luo H, Morgan A, Zhang J, Wong J, Yuan J, Esfandiarei M, Gao G, Cheung C, McManus BM. Stress-activated protein kinases are involved in coxsackievirus B3 viral progeny release. Journal of Virology. 79: 13875-81. PMID 16254323 DOI: 10.1128/Jvi.79.22.13875-13881.2005  0.342
2005 Rezai N, Corbel SY, Dabiri D, Kerjner A, Rossi FM, McManus BM, Podor TJ. Bone marrow-derived recipient cells in murine transplanted hearts: potential roles and the effect of immunosuppression. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 982-91. PMID 16205656 DOI: 10.1038/Labinvest.3700302  0.321
2005 Cheung PK, Yuan J, Zhang HM, Chau D, Yanagawa B, Suarez A, McManus B, Yang D. Specific interactions of mouse organ proteins with the 5'untranslated region of coxsackievirus B3: potential determinants of viral tissue tropism. Journal of Medical Virology. 77: 414-24. PMID 16173012 DOI: 10.1002/Jmv.20470  0.568
2005 Liu Z, Yuan J, Yanagawa B, Qiu D, McManus BM, Yang D. Coxsackievirus-induced myocarditis: new trends in treatment. Expert Review of Anti-Infective Therapy. 3: 641-50. PMID 16107202 DOI: 10.1586/14787210.3.4.641  0.553
2005 Yanagawa B, Taylor L, Deisher TA, Ng R, Schreiner GF, Triche TJ, Yang D, McManus BM. Affymetrix oligonucleotide analysis of gene expression in the injured heart. Methods in Molecular Medicine. 112: 305-20. PMID 16010026 DOI: 10.1385/1-59259-879-X:305  0.531
2005 Rezai N, Walinski H, Kerjner A, Bohunek L, Rossi FM, McManus BM, Podor TJ. Methods for examining stem cells in post-ischemic and transplanted hearts. Methods in Molecular Medicine. 112: 223-38. PMID 16010020 DOI: 10.1385/1-59259-879-X:223  0.312
2005 Zhang HM, Yuan J, Cheung P, Chau D, Wong BW, McManus BM, Yang D. Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression. Molecular and Cellular Biology. 25: 6247-58. PMID 15988033 DOI: 10.1128/Mcb.25.14.6247-6258.2005  0.375
2005 Si X, McManus BM, Zhang J, Yuan J, Cheung C, Esfandiarei M, Suarez A, Morgan A, Luo H. Pyrrolidine dithiocarbamate reduces coxsackievirus B3 replication through inhibition of the ubiquitin-proteasome pathway. Journal of Virology. 79: 8014-23. PMID 15956547 DOI: 10.1128/Jvi.79.13.8014-8023.2005  0.367
2005 Choy JC, Cruz RP, Kerjner A, Geisbrecht J, Sawchuk T, Fraser SA, Hudig D, Bleackley RC, Jirik FR, McManus BM, Granville DJ. Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 494-9. PMID 15707403 DOI: 10.1111/J.1600-6143.2004.00710.X  0.631
2005 Heine H, Bohunek L, Johnson A, So L, Pate G, Fong P, McManus BM, Rossi F, Podor T. 248 INTRAVENOUS AND DIRECT MYOCARDIAL INJECTION OF SIDE POPULATION STEM CELLS LABELED WITH GREEN FLUORESCENT PROTEIN INTO A MURINE MODEL OF MYOCARDIAL INFARCTION Journal of Investigative Medicine. 53: S121.2-S121. DOI: 10.2310/6650.2005.00005.247  0.314
2004 Hunter AL, Cruz RP, Cheyne BM, McManus BM, Granville DJ. Cytochrome p450 enzymes and cardiovascular disease. Canadian Journal of Physiology and Pharmacology. 82: 1053-60. PMID 15644946 DOI: 10.1139/Y04-118  0.561
2004 Moien-Afshari F, Skarsgard PL, McManus BM, Laher I. Cardiac transplantation and resistance artery myogenic tone. Canadian Journal of Physiology and Pharmacology. 82: 840-8. PMID 15573144 DOI: 10.1139/Y04-100  0.324
2004 Choy JC, Hung VH, Hunter AL, Cheung PK, Motyka B, Goping IS, Sawchuk T, Bleackley RC, Podor TJ, McManus BM, Granville DJ. Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 2245-50. PMID 15472125 DOI: 10.1161/01.Atv.0000147162.51930.B7  0.618
2004 Choy JC, Kerjner A, Wong BW, McManus BM, Granville DJ. Perforin mediates endothelial cell death and resultant transplant vascular disease in cardiac allografts. The American Journal of Pathology. 165: 127-33. PMID 15215168 DOI: 10.1016/S0002-9440(10)63281-6  0.604
2004 Yuan J, Cheung PK, Zhang H, Chau D, Yanagawa B, Cheung C, Luo H, Wang Y, Suarez A, McManus BM, Yang D. A phosphorothioate antisense oligodeoxynucleotide specifically inhibits coxsackievirus B3 replication in cardiomyocytes and mouse hearts. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 703-14. PMID 15094712 DOI: 10.1038/Labinvest.3700083  0.582
2004 Yanagawa B, Spiller OB, Proctor DG, Choy J, Luo H, Zhang HM, Suarez A, Yang D, McManus BM. Soluble recombinant coxsackievirus and adenovirus receptor abrogates coxsackievirus b3-mediated pancreatitis and myocarditis in mice. The Journal of Infectious Diseases. 189: 1431-9. PMID 15073680 DOI: 10.1086/382598  0.533
2004 Esfandiarei M, Luo H, Yanagawa B, Suarez A, Dabiri D, Zhang J, McManus BM. Protein kinase B/Akt regulates coxsackievirus B3 replication through a mechanism which is not caspase dependent. Journal of Virology. 78: 4289-98. PMID 15047842 DOI: 10.1128/Jvi.78.8.4289-4298.2004  0.591
2004 Choy JC, Lui AH, Moien-Afshari F, Wei K, Yanagawa B, McManus BM, Laher I. Coxsackievirus B3 infection compromises endothelial-dependent vasodilation of coronary resistance arteries. Journal of Cardiovascular Pharmacology. 43: 39-47. PMID 14668566 DOI: 10.1097/00005344-200401000-00007  0.556
2004 Rezai N, Kerjner A, Corbel S, Rossi F, McManus B, Podor T. The effect of immunosuppression on bone marrow-derived recipient cells in murine cardiac allografts The Journal of Heart and Lung Transplantation. 23: S124. DOI: 10.1016/J.Healun.2003.11.244  0.349
2004 Choy JC, Kerjner A, Wong BW, McManus BM, Granville DJ. THE ROLE OF PERFORIN IN TRANSPLANT VASCULAR DISEASE Cardiovascular Pathology. 13: 136. DOI: 10.1016/J.Carpath.2004.03.410  0.565
2004 Wing B, Wong C, Rahmani M, Luo Z, Loo S, Wong D, Yanagawa B, Yang D, McManus BM. MODULATION OF ENDOTHELIAL TIGHT JUNCTIONS AND VASCULAR PERMEABILITY BY VASCULAR ENDOTHELIAL GROWTH FACTOR Cardiovascular Pathology. 13: 41-42. DOI: 10.1016/J.Carpath.2004.03.116  0.485
2004 Cruz RP, Rezai N, Walinski H, Luo Z, Triche T, McManus BM, Granville DJ. MITRAL VALVE DISEASE: A GENOMIC COMPARISON OF VALVULAR INTERSTITIAL CELLS FROM NORMAL, FLOPPY AND RHEUMATIC VALVES Cardiovascular Pathology. 13: 32. DOI: 10.1016/J.Carpath.2004.03.089  0.553
2004 Cheung CT, Yanagawa B, Luo H, Zhang J, McManus BM. Cardiomyocytes upregulate matrix metalloproteinases following coxsackievirus infection Journal of Cardiac Failure. 10: S57. DOI: 10.1016/J.Cardfail.2004.06.139  0.518
2003 Yanagawa B, McManus B, Hollander Z, Luo H, Ng R, Yang D. From gene expression profiles to biological validation in enteroviral heart disease. Experimental and Clinical Cardiology. 8: 125-30. PMID 19641703  0.53
2003 Moien-Afshari F, McManus BM, Laher I. Immunosuppression and transplant vascular disease: benefits and adverse effects. Pharmacology & Therapeutics. 100: 141-56. PMID 14609717 DOI: 10.1016/J.Pharmthera.2003.08.002  0.335
2003 Choy JC, Podor TJ, Yanagawa B, Lai JC, Granville DJ, Walker DC, McManus BM. The regulation and consequences of immune-mediated cell death in atheromatous diseases. Cardiovascular Toxicology. 3: 269-82. PMID 14555792 DOI: 10.1385/Ct:3:3:269  0.684
2003 Lai JC, Tranfield EM, Walker DC, Dyck J, Kerjner A, Loo S, English D, Wong D, McDonald PC, Moghadasian MH, Wilson JE, McManus BM. Ultrastructural evidence of early endothelial damage in coronary arteries of rat cardiac allografts. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 22: 993-1004. PMID 12957609 DOI: 10.1016/S1053-2498(02)01163-4  0.316
2003 Carthy CM, Yanagawa B, Luo H, Granville DJ, Yang D, Cheung P, Cheung C, Esfandiarei M, Rudin CM, Thompson CB, Hunt DW, McManus BM. Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection. Virology. 313: 147-57. PMID 12951029 DOI: 10.1016/S0042-6822(03)00242-3  0.791
2003 Luo H, Zhang J, Cheung C, Suarez A, McManus BM, Yang D. Proteasome inhibition reduces coxsackievirus B3 replication in murine cardiomyocytes. The American Journal of Pathology. 163: 381-5. PMID 12875959 DOI: 10.1016/S0002-9440(10)63667-X  0.356
2003 Zhang HM, Yuan J, Cheung P, Luo H, Yanagawa B, Chau D, Stephan-Tozy N, Wong BW, Zhang J, Wilson JE, McManus BM, Yang D. Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication. The Journal of Biological Chemistry. 278: 33011-9. PMID 12819192 DOI: 10.1074/Jbc.M305352200  0.585
2003 Zhang HM, Cheung P, Yanagawa B, McManus BM, Yang DC. BNips: a group of pro-apoptotic proteins in the Bcl-2 family. Apoptosis : An International Journal On Programmed Cell Death. 8: 229-36. PMID 12766483 DOI: 10.1023/A:1023616620970  0.503
2003 Choy JC, McDonald PC, Suarez AC, Hung VH, Wilson JE, McManus BM, Granville DJ. Granzyme B in atherosclerosis and transplant vascular disease: association with cell death and atherosclerotic disease severity. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 16: 460-70. PMID 12748253 DOI: 10.1097/01.Mp.0000067424.12280.Bc  0.608
2003 Loucks EB, Godin DV, Walley KR, McManus BM, Rahimian R, Granville DJ, Hong JM, Aktary FM, Qayumi AK. Role of platelet activating factor in cardiac dysfunction, apoptosis and nitric oxide synthase mRNA expression in the ischemic-reperfused rabbit heart. The Canadian Journal of Cardiology. 19: 267-74. PMID 12677282  0.53
2003 Chockalingam A, Yanagawa B, McManus BM. Frontiers in cardiovascular research: forging further scientific collaborations between Canada and the United States. The Canadian Journal of Cardiology. 19: 94-5. PMID 12571700  0.401
2003 Yanagawa B, Spiller OB, Choy J, Luo H, Cheung P, Zhang HM, Goodfellow IG, Evans DJ, Suarez A, Yang D, McManus BM. Coxsackievirus B3-associated myocardial pathology and viral load reduced by recombinant soluble human decay-accelerating factor in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 75-85. PMID 12533688 DOI: 10.1097/01.Lab.0000049349.56211.09  0.581
2003 Yang D, Cheung P, Sun Y, Yuan J, Zhang H, Carthy CM, Anderson DR, Bohunek L, Wilson JE, McManus BM. A shine-dalgarno-like sequence mediates in vitro ribosomal internal entry and subsequent scanning for translation initiation of coxsackievirus B3 RNA. Virology. 305: 31-43. PMID 12504538 DOI: 10.1006/Viro.2002.1770  0.716
2003 Luo H, Zhang J, Dastvan F, Yanagawa B, Reidy MA, Zhang HM, Yang D, Wilson JE, McManus BM. Ubiquitin-dependent proteolysis of cyclin D1 is associated with coxsackievirus-induced cell growth arrest. Journal of Virology. 77: 1-9. PMID 12477805 DOI: 10.1128/Jvi.77.1.1-9.2003  0.556
2003 Choy J, Hung V, Myers J, Motyka B, Goping I, Sawchuck T, Bleackley R, McManus B, Granville D. Granzyme B, a cytotoxic immune protease, induces apoptosis of smooth muscle cells in the absence of perforin The Journal of Heart and Lung Transplantation. 22: S155. DOI: 10.1016/S1053-2498(02)00945-2  0.579
2002 McManus BM, Yanagawa B, Rezai N, Luo H, Taylor L, Zhang M, Yuan J, Buckley J, Triche T, Schreiner G, Yang D. Genetic determinants of coxsackievirus B3 pathogenesis. Annals of the New York Academy of Sciences. 975: 169-79. PMID 12538163 DOI: 10.1111/J.1749-6632.2002.Tb05950.X  0.577
2002 Cheung P, Zhang M, Yuan J, Chau D, Yanagawa B, McManus B, Yang D. Specific interactions of HeLa cell proteins with Coxsackievirus B3 RNA: La autoantigen binds differentially to multiple sites within the 5' untranslated region. Virus Research. 90: 23-36. PMID 12457960 DOI: 10.1016/S0168-1702(02)00138-7  0.535
2002 Zhang HM, Yanagawa B, Cheung P, Luo H, Yuan J, Chau D, Wang A, Bohunek L, Wilson JE, McManus BM, Yang D. Nip21 gene expression reduces coxsackievirus B3 replication by promoting apoptotic cell death via a mitochondria-dependent pathway. Circulation Research. 90: 1251-8. PMID 12089062 DOI: 10.1161/01.Res.0000024690.69379.5C  0.606
2002 Luo H, Yanagawa B, Zhang J, Luo Z, Zhang M, Esfandiarei M, Carthy C, Wilson JE, Yang D, McManus BM. Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway. Journal of Virology. 76: 3365-73. PMID 11884562 DOI: 10.1128/Jvi.76.7.3365-3373.2002  0.788
2001 Miller LW, Granville DJ, Narula J, McManus BM. Apoptosis in cardiac transplant rejection. Cardiology Clinics. 19: 141-54. PMID 11787808 DOI: 10.1016/S0733-8651(05)70200-9  0.636
2001 Granville DJ, Ruehlmann DO, Choy JC, Cassidy BA, Hunt DW, van Breemen C, McManus BM. Bcl-2 increases emptying of endoplasmic reticulum Ca2+ stores during photodynamic therapy-induced apoptosis. Cell Calcium. 30: 343-50. PMID 11733941 DOI: 10.1054/Ceca.2001.0243  0.555
2001 Granville DJ, Jiang H, McManus BM, Hunt DW. Fas ligand and TRAIL augment the effect of photodynamic therapy on the induction of apoptosis in JURKAT cells. International Immunopharmacology. 1: 1831-40. PMID 11562074 DOI: 10.1016/S1567-5769(01)00107-2  0.609
2001 Choy JC, Granville DJ, Hunt DW, McManus BM. Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis. Journal of Molecular and Cellular Cardiology. 33: 1673-90. PMID 11549346 DOI: 10.1006/Jmcc.2001.1419  0.626
2001 Granville DJ, Cassidy BA, Ruehlmann DO, Choy JC, Brenner C, Kroemer G, van Breemen C, Margaron P, Hunt DW, McManus BM. Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis. The American Journal of Pathology. 159: 305-11. PMID 11438477 DOI: 10.1016/S0002-9440(10)61696-3  0.608
2001 Wang A, Cheung PK, Zhang H, Carthy CM, Bohunek L, Wilson JE, McManus BM, Yang D. Specific inhibition of coxsackievirus B3 translation and replication by phosphorothioate antisense oligodeoxynucleotides. Antimicrobial Agents and Chemotherapy. 45: 1043-52. PMID 11257014 DOI: 10.1128/Aac.45.4.1043-1052.2001  0.737
2001 Granville DJ, McManus BM, Hunt DW. Photodynamic therapy: shedding light on the biochemical pathways regulating porphyrin-mediated cell death. Histology and Histopathology. 16: 309-17. PMID 11193207 DOI: 10.14670/Hh-16.309  0.606
2000 Taylor LA, Carthy CM, Yang D, Saad K, Wong D, Schreiner G, Stanton LW, McManus BM. Host gene regulation during coxsackievirus B3 infection in mice: assessment by microarrays. Circulation Research. 87: 328-34. PMID 10948068 DOI: 10.1161/01.Res.87.4.328  0.743
2000 Granville DJ, Carthy CM, Jiang H, Levy JG, McManus BM, Matroule JY, Piette J, Hunt DW. Nuclear factor-kappaB activation by the photochemotherapeutic agent verteporfin. Blood. 95: 256-62. PMID 10607710  0.783
2000 Granville DJ, Carthy CM, Jiang H, Levy JG, McManus BM, Matroule J, Piette J, Hunt DWC. Nuclear factor-κB activation by the photochemotherapeutic agent verteporfin Blood. 95: 256-262. DOI: 10.1182/Blood.V95.1.256.001K29_256_262  0.575
1999 Yu JZ, Wilson JE, Wood SM, Kandolf R, Klingel K, Yang D, McManus BM. Secondary heterotypic versus homotypic infection by Coxsackie B group viruses: impact on early and late histopathological lesions and virus genome prominence. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 8: 93-102. PMID 10724506 DOI: 10.1016/S1054-8807(98)00025-8  0.329
1999 Dong C, Granville DJ, Tuffnel CE, Kenyon J, English D, Wilson JE, McManus BM. Bax and apoptosis in acute and chronic rejection of rat cardiac allografts. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 1643-53. PMID 10616213  0.593
1999 Liu Z, Carthy CM, Cheung P, Bohunek L, Wilson JE, McManus BM, Yang D. Structural and functional analysis of the 5' untranslated region of coxsackievirus B3 RNA: In vivo translational and infectivity studies of full-length mutants. Virology. 265: 206-17. PMID 10600593 DOI: 10.1006/Viro.1999.0048  0.736
1999 Granville DJ, Shaw JR, Leong S, Carthy CM, Margaron P, Hunt DW, McManus BM. Release of cytochrome c, Bax migration, Bid cleavage, and activation of caspases 2, 3, 6, 7, 8, and 9 during endothelial cell apoptosis. The American Journal of Pathology. 155: 1021-5. PMID 10514382 DOI: 10.1016/S0002-9440(10)65202-9  0.788
1999 Carthy CM, Granville DJ, Jiang H, Levy JG, Rudin CM, Thompson CB, McManus BM, Hunt DW. Early release of mitochondrial cytochrome c and expression of mitochondrial epitope 7A6 with a porphyrin-derived photosensitizer: Bcl-2 and Bcl-xL overexpression do not prevent early mitochondrial events but still depress caspase activity. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 953-65. PMID 10462033  0.775
1999 Granville DJ, Jiang H, An MT, Levy JG, McManus BM, Hunt DW. Bcl-2 overexpression blocks caspase activation and downstream apoptotic events instigated by photodynamic therapy. British Journal of Cancer. 79: 95-100. PMID 10408699 DOI: 10.1038/Sj.Bjc.6690017  0.62
1999 Jiang H, Granville DJ, McManus BM, Levy JG, Hunt DW. Selective depletion of a thymocyte subset in vitro with an immunomodulatory photosensitizer. Clinical Immunology (Orlando, Fla.). 91: 178-87. PMID 10227810 DOI: 10.1006/Clim.1999.4695  0.553
1999 Huber M, Watson KA, Selinka HC, Carthy CM, Klingel K, McManus BM, Kandolf R. Cleavage of RasGAP and phosphorylation of mitogen-activated protein kinase in the course of coxsackievirus B3 replication. Journal of Virology. 73: 3587-94. PMID 10196249 DOI: 10.1128/Jvi.73.5.3587-3594.1999  0.735
1999 Yang D, Yu J, Luo Z, Carthy CM, Wilson JE, Liu Z, McManus BM. Viral myocarditis: identification of five differentially expressed genes in coxsackievirus B3-infected mouse heart. Circulation Research. 84: 704-12. PMID 10189358 DOI: 10.1161/01.Res.84.6.704  0.752
1999 Kanda T, Koike H, Arai M, Wilson JE, Carthy CM, Yang D, McManus BM, Nagai R, Kobayashi I. Increased severity of viral myocarditis in mice lacking lymphocyte maturation. International Journal of Cardiology. 68: 13-22. PMID 10077396 DOI: 10.1016/S0167-5273(98)00250-2  0.73
1999 Koglin J, Granville DJ, Glysing-Jensen T, Mudgett JS, Carthy CM, McManus BM, Russell ME. Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis. Circulation. 99: 836-42. PMID 9989972 DOI: 10.1161/01.Cir.99.6.836  0.786
1999 McDonald PC, Wong D, Granville DJ, McManus BM. Emerging roles of endothelial cells and smooth muscle cells in transplant vascular disease Transplantation Reviews. 13: 109-127. DOI: 10.1016/S0955-470X(99)80070-6  0.607
1998 Granville DJ, Carthy CM, Yang D, Hunt DW, McManus BM. Interaction of viral proteins with host cell death machinery. Cell Death and Differentiation. 5: 653-9. PMID 10200520 DOI: 10.1038/Sj.Cdd.4400388  0.792
1998 Granville DJ, Carthy CM, Jiang H, Shore GC, McManus BM, Hunt DW. Rapid cytochrome c release, activation of caspases 3, 6, 7 and 8 followed by Bap31 cleavage in HeLa cells treated with photodynamic therapy. Febs Letters. 437: 5-10. PMID 9804161 DOI: 10.1016/S0014-5793(98)01193-4  0.785
1998 Skarsgard PL, McManus BM, Breemen Cv, Laher I. Endothelium-smooth muscle interaction in cardiac transplantation. Clinical and Experimental Pharmacology and Physiology. 25: 836-840. PMID 9784926 DOI: 10.1111/J.1440-1681.1998.Tb02164.X  0.343
1998 Granville DJ, Carthy CM, Hunt DW, McManus BM. Apoptosis: molecular aspects of cell death and disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 78: 893-913. PMID 9714178  0.722
1998 Carthy CM, Granville DJ, Watson KA, Anderson DR, Wilson JE, Yang D, Hunt DW, McManus BM. Caspase activation and specific cleavage of substrates after coxsackievirus B3-induced cytopathic effect in HeLa cells. Journal of Virology. 72: 7669-75. PMID 9696873 DOI: 10.1128/Jvi.72.9.7669-7675.1998  0.798
1998 Granville DJ, Jiang H, An MT, Levy JG, McManus BM, Hunt DW. Overexpression of Bcl-X(L) prevents caspase-3-mediated activation of DNA fragmentation factor (DFF) produced by treatment with the photochemotherapeutic agent BPD-MA. Febs Letters. 422: 151-4. PMID 9489995 DOI: 10.1016/S0014-5793(97)01616-5  0.596
1997 Carthy CM, Yang D, Anderson DR, Wilson JE, McManus BM. Myocarditis as systemic disease: new perspectives on pathogenesis. Clinical and Experimental Pharmacology & Physiology. 24: 997-1003. PMID 9406676 DOI: 10.1111/J.1440-1681.1997.Tb02739.X  0.762
1997 Anderson DR, Carthy CM, Wilson JE, Yang D, Devine DV, McManus BM. Complement component 3 interactions with coxsackievirus B3 capsid proteins: innate immunity and the rapid formation of splenic antiviral germinal centers. Journal of Virology. 71: 8841-5. PMID 9343244 DOI: 10.1128/Jvi.71.11.8841-8845.1997  0.736
1997 Klingel K, Stephan S, Sauter M, Zell R, McManus BM, Bültmann B, Kandolf R. Pathogenesis of murine enterovirus myocarditis: virus dissemination and immune cell targets. Journal of Virology. 70: 8888-95. PMID 8971018 DOI: 10.1128/Jvi.70.12.8888-8895.1996  0.352
1996 Dong C, Redenbach D, Wood S, Battistini B, Wilson JE, McManus BM. The pathogenesis of cardiac allograft vasculopathy. Current Opinion in Cardiology. 11: 183-90. PMID 8736690 DOI: 10.1097/00001573-199603000-00012  0.365
1996 Anderson DR, Wilson JE, Carthy CM, Yang D, Kandolf R, McManus BM. Direct interactions of coxsackievirus B3 with immune cells in the splenic compartment of mice susceptible or resistant to myocarditis. Journal of Virology. 70: 4632-45. PMID 8676490 DOI: 10.1128/Jvi.70.7.4632-4645.1996  0.74
1996 Utans U, Quist WC, McManus BM, Wilson JE, Arceci RJ, Wallace AF, Russell ME. Allograft inflammatory factory-1. A cytokine-responsive macrophage molecule expressed in transplanted human hearts. Transplantation. 61: 1387-92. PMID 8629302 DOI: 10.1097/00007890-199605150-00018  0.312
1996 Kanda T, McManus JE, Nagai R, Imai S, Suzuki T, Yang D, McManus BM, Kobayashi I. Modification of viral myocarditis in mice by interleukin-6. Circulation Research. 78: 848-56. PMID 8620605 DOI: 10.1161/01.Res.78.5.848  0.309
1992 Costanzo-Nordin MR, Hubbell EA, O'Sullivan EJ, Johnson MR, Mullen GM, Heroux AL, Kao WG, McManus BM, Pifarre R, Robinson JA. Successful treatment of heart transplant rejection with photopheresis. Transplantation. 53: 808-15. PMID 1566346 DOI: 10.1097/00007890-199204000-00021  0.314
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