Dale W. Laird - Publications

Affiliations: 
The University of Western Ontario (Canada) 
Area:
Cell Biology

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bedoukian EC, Rentas S, Skraban C, Shao Q, Treat J, Laird DW, Sullivan KE. Palmoplantar keratoderma with deafness phenotypic variability in a patient with an inherited GJB2 frameshift variant and novel missense variant. Molecular Genetics & Genomic Medicine. e1574. PMID 33443819 DOI: 10.1002/mgg3.1574  0.48
2020 Au A, Shao Q, White KK, Lucaciu SA, Esseltine JL, Barr K, Laird DW. Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes. Biomolecules. 10. PMID 33066499 DOI: 10.3390/biom10101443  0.48
2020 Beach R, Abitbol JM, Allman BL, Esseltine JL, Shao Q, Laird DW. Mutations Linked to Hearing Loss Exhibit Differential Trafficking and Functional Defects as Revealed in Cochlear-Relevant Cells. Frontiers in Cell and Developmental Biology. 8: 215. PMID 32300592 DOI: 10.3389/Fcell.2020.00215  0.48
2019 Shao Q, Esseltine JL, Huang T, Novielli-Kuntz N, Ching JE, Sampson J, Laird DW. Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence. Biomolecules. 9. PMID 31514306 DOI: 10.3390/biom9090474  0.48
2019 Shum MG, Shao Q, Lajoie P, Laird DW. Destination and consequences of Panx1 and mutant expression in polarized MDCK cells. Experimental Cell Research. PMID 31102595 DOI: 10.1016/j.yexcr.2019.05.016  0.48
2018 Press E, Alaga KC, Barr K, Shao Q, Bosen F, Willecke K, Laird DW. Correction to: Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice. Cell Death & Disease. 9: 630. PMID 29795380 DOI: 10.1038/s41419-018-0639-1  0.48
2017 Press E, Alaga KC, Barr K, Shao Q, Bosen F, Willecke K, Laird DW. Disease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice. Cell Death & Disease. 8: e2845. PMID 28569788 DOI: 10.1038/cddis.2017.234  0.48
2017 Press ER, Shao Q, Kelly JJ, Chin K, Alaga A, Laird DW. Induction of cell death and gain-of-function properties of connexin26 mutants predict severity of skin disorders and hearing loss. The Journal of Biological Chemistry. PMID 28428247 DOI: 10.1074/jbc.M116.770917  0.48
2017 Esseltine JL, Shao Q, Brooks C, Sampson J, Betts DH, Séguin C, Laird DW. Connexin43 Mutant Patient-Derived Induced Pluripotent Stem Cells Exhibit Altered Differentiation Potential. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28177159 DOI: 10.1002/jbmr.3098  0.48
2016 Johnson RG, Le HC, Evenson K, Loberg SW, Myslajek TM, Prabhu A, Manley AM, O'Shea C, Grunenwald H, Haddican M, Fitzgerald PM, Robinson T, Cisterna BA, Sáez JC, Liu TF, ... Laird DW, et al. Connexin Hemichannels: Methods for Dye Uptake and Leakage. The Journal of Membrane Biology. PMID 27586664 DOI: 10.1007/S00232-016-9925-Y  0.48
2016 Kelly JJ, Esseltine J, Shao Q, Jabs EW, Sampson J, Auranen M, Bai D, Laird DW. Specific functional pathologies of Cx43 mutations associated with oculodentodigital dysplasia. Molecular Biology of the Cell. PMID 27226478 DOI: 10.1091/mbc.E16-01-0062  0.48
2016 Siddiqui M, Swarbreck S, Shao Q, Secor D, Peng T, Laird DW, Tyml K. Critical Role of Cx40 in Reduced Endothelial Electrical Coupling by Lipopolysaccharide and Hypoxia-Reoxygenation. Journal of Vascular Research. 52: 396-403. PMID 27194161 DOI: 10.1159/000445772  0.48
2016 Shao Q, Lindstrom K, Shi R, Kelly J, Schroeder A, Juusola J, Levine KL, Esseltine JL, Penuela S, Jackson MF, Laird DW. A germline variant in PANX1 has reduced channel function and is associated with multisystem dysfunction. The Journal of Biological Chemistry. PMID 27129271 DOI: 10.1074/jbc.M116.717934  0.48
2016 Laird DW, Naus CC. Gerald M. Kidder - bridging the gap in cell and developmental biology. Seminars in Cell & Developmental Biology. 50: 1-3. PMID 26940063 DOI: 10.1016/j.semcdb.2016.02.017  0.48
2016 Merrifield PA, Laird DW. Connexins in skeletal muscle development and disease. Seminars in Cell & Developmental Biology. 50: 67-73. PMID 26688333 DOI: 10.1016/j.semcdb.2015.12.001  0.48
2016 Stewart MKG, Plante I, Penuela S, Laird DW. Loss of Panx1 impairs mammary gland development at lactation: Implications for breast tumorigenesis Plos One. 11. DOI: 10.1371/journal.pone.0154162  0.48
2016 Caskenette D, Penuela S, Lee V, Barr K, Beier F, Laird DW, Willmore KE. Global deletion of Panx3 produces multiple phenotypic effects in mouse humeri and femora Journal of Anatomy. DOI: 10.1111/joa.12437  0.48
2015 Stewart MK, Bechberger JF, Welch I, Naus CC, Laird DW. Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer. Oncotarget. 6: 37185-99. PMID 26439696 DOI: 10.18632/oncotarget.5953  0.48
2015 Kelly JJ, Shao Q, Jagger DJ, Laird DW. Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions. Journal of Cell Science. PMID 26359304 DOI: 10.1242/jcs.174698  0.48
2015 Esseltine JL, Shao Q, Huang T, Kelly JJ, Sampson J, Laird DW. Manipulating Cx43 expression triggers gene reprogramming events in dermal fibroblasts from oculodentodigital dysplasia patients. The Biochemical Journal. PMID 26349540 DOI: 10.1042/BJ20150652  0.48
2015 Moon PM, Penuela S, Barr K, Khan S, Pin CL, Welch I, Attur M, Abramson SB, Laird DW, Beier F. Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis. Journal of Molecular Medicine (Berlin, Germany). PMID 26138248 DOI: 10.1007/s00109-015-1311-1  0.48
2015 Goodson WH, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, ... ... Laird DW, et al. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis. 36: S254-96. PMID 26106142 DOI: 10.1093/Carcin/Bgv039  0.48
2015 Nahta R, Al-Mulla F, Al-Temaimi R, Amedei A, Andrade-Vieira R, Bay S, G Brown D, Calaf GM, Castellino RC, Cohen-Solal KA, Colacci A, Cruickshanks N, Dent P, Di Fiore R, Forte S, ... ... Laird DW, et al. Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis. 36: S2-S18. PMID 26106139 DOI: 10.1093/Carcin/Bgv028  0.48
2015 Kelly JJ, Simek J, Laird DW. Mechanisms linking connexin mutations to human diseases. Cell and Tissue Research. 360: 701-21. PMID 25398718 DOI: 10.1007/s00441-014-2024-4  0.48
2015 Molica F, Morel S, Meens MJ, Denis JF, Bradfield PF, Penuela S, Zufferey A, Monyer H, Imhof BA, Chanson M, Laird DW, Fontana P, Kwak BR. Functional role of a polymorphism in the pannexin1 gene in collageninduced platelet aggregation Thrombosis and Haemostasis. 114: 325-336. DOI: 10.1160/TH14-11-0981  0.48
2015 Laird DW, Lampe PD, Johnson RG. Cellular small talk Scientific American. 312: 70-77. DOI: 10.1038/scientificamerican0515-70  0.48
2014 Xiao D, Chen S, Shao Q, Chen J, Bijian K, Laird DW, Alaoui-Jamali MA. Dynamin 2 interacts with connexin 26 to regulate its degradation and function in gap junction formation. The International Journal of Biochemistry & Cell Biology. 55: 288-97. PMID 25263585 DOI: 10.1016/J.Biocel.2014.09.021  0.48
2014 Boyd-Tressler A, Penuela S, Laird DW, Dubyak GR. Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism. The Journal of Biological Chemistry. 289: 27246-63. PMID 25112874 DOI: 10.1074/Jbc.M114.590240  0.48
2014 Stewart MK, Plante I, Bechberger JF, Naus CC, Laird DW. Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function. Plos One. 9: e101546. PMID 24988191 DOI: 10.1371/journal.pone.0101546  0.48
2014 Sun Y, Tong X, Chen H, Huang T, Shao Q, Huang W, Laird DW, Bai D. An atrial-fibrillation-linked connexin40 mutant is retained in the endoplasmic reticulum and impairs the function of atrial gap-junction channels. Disease Models & Mechanisms. 7: 561-9. PMID 24626989 DOI: 10.1242/dmm.013813  0.48
2014 Penuela S, Kelly JJ, Churko JM, Barr KJ, Berger AC, Laird DW. Panx1 regulates cellular properties of keratinocytes and dermal fibroblasts in skin development and wound healing. The Journal of Investigative Dermatology. 134: 2026-35. PMID 24522432 DOI: 10.1038/Jid.2014.86  0.48
2014 Berger AC, Kelly JJ, Lajoie P, Shao Q, Laird DW. Mutations in Cx30 that are linked to skin disease and non-syndromic hearing loss exhibit several distinct cellular pathologies. Journal of Cell Science. 127: 1751-64. PMID 24522190 DOI: 10.1242/Jcs.138230  0.48
2014 Ableser MJ, Penuela S, Lee J, Shao Q, Laird DW. Connexin43 reduces melanoma growth within a keratinocyte microenvironment and during tumorigenesis in vivo. The Journal of Biological Chemistry. 289: 1592-603. PMID 24297173 DOI: 10.1074/jbc.M113.507228  0.48
2014 Huang T, Shao Q, Barr K, Simek J, Fishman GI, Laird DW. Myogenic bladder defects in mouse models of human oculodentodigital dysplasia. The Biochemical Journal. 457: 441-9. PMID 24228978 DOI: 10.1042/BJ20130810  0.48
2013 Huang T, Shao Q, MacDonald A, Xin L, Lorentz R, Bai D, Laird DW. Autosomal recessive GJA1 (Cx43) gene mutations cause oculodentodigital dysplasia by distinct mechanisms. Journal of Cell Science. 126: 2857-66. PMID 23606748 DOI: 10.1242/jcs.123315  0.48
2013 Stewart MK, Gong XQ, Barr KJ, Bai D, Fishman GI, Laird DW. The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice. The Biochemical Journal. 449: 401-13. PMID 23075222 DOI: 10.1042/BJ20121070  0.48
2013 Kranz K, Dorgau B, Pottek M, Herrling R, Schultz K, Bolte P, Monyer H, Penuela S, Laird DW, Dedek K, Weiler R, Janssen-Bienhold U. Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout. The Journal of Comparative Neurology. 521: 1119-35. PMID 22965528 DOI: 10.1002/Cne.23223  0.48
2012 Lohman AW, Weaver JL, Billaud M, Sandilos JK, Griffiths R, Straub AC, Penuela S, Leitinger N, Laird DW, Bayliss DA, Isakson BE. S-nitrosylation inhibits pannexin 1 channel function. The Journal of Biological Chemistry. 287: 39602-12. PMID 23033481 DOI: 10.1074/Jbc.M112.397976  0.48
2012 Cowan KN, Langlois S, Penuela S, Cowan BJ, Laird DW. Pannexin1 and Pannexin3 exhibit distinct localization patterns in human skin appendages and are regulated during keratinocyte differentiation and carcinogenesis. Cell Communication & Adhesion. 19: 45-53. PMID 22947051 DOI: 10.3109/15419061.2012.712575  0.48
2012 Shao Q, Liu Q, Lorentz R, Gong XQ, Bai D, Shaw GS, Laird DW. Structure and functional studies of N-terminal Cx43 mutants linked to oculodentodigital dysplasia. Molecular Biology of the Cell. 23: 3312-21. PMID 22809623 DOI: 10.1091/mbc.E12-02-0128  0.48
2012 Churko JM, Kelly JJ, Macdonald A, Lee J, Sampson J, Bai D, Laird DW. The G60S Cx43 mutant enhances keratinocyte proliferation and differentiation. Experimental Dermatology. 21: 612-8. PMID 22775996 DOI: 10.1111/j.1600-0625.2012.01532.x  0.48
2012 Lampe PD, Laird DW. Introductory paper of the special issue on gap junctions in honor of Ross Johnson. The Journal of Membrane Biology. 245: 217-9. PMID 22772443 DOI: 10.1007/S00232-012-9486-7  0.48
2012 Penuela S, Gyenis L, Ablack A, Churko JM, Berger AC, Litchfield DW, Lewis JD, Laird DW. Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype. The Journal of Biological Chemistry. 287: 29184-93. PMID 22753409 DOI: 10.1074/Jbc.M112.377176  0.48
2012 Lohman AW, Billaud M, Straub AC, Johnstone SR, Best AK, Lee M, Barr K, Penuela S, Laird DW, Isakson BE. Expression of pannexin isoforms in the systemic murine arterial network. Journal of Vascular Research. 49: 405-16. PMID 22739252 DOI: 10.1159/000338758  0.48
2012 Pocrnich CE, Shao Q, Liu H, Feng MM, Harasym S, Savage M, Khimdas S, Laird DW, Hutnik CM. The effect of connexin43 on the level of vascular endothelial growth factor in human retinal pigment epithelial cells. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 250: 515-22. PMID 22138732 DOI: 10.1007/s00417-011-1871-x  0.48
2011 Bond SR, Lau A, Penuela S, Sampaio AV, Underhill TM, Laird DW, Naus CC. Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2911-22. PMID 21915903 DOI: 10.1002/jbmr.509  0.48
2011 Churko JM, Chan J, Shao Q, Laird DW. The G60S connexin43 mutant regulates hair growth and hair fiber morphology in a mouse model of human oculodentodigital dysplasia. The Journal of Investigative Dermatology. 131: 2197-204. PMID 21716323 DOI: 10.1038/Jid.2011.183  0.48
2011 Gehi R, Shao Q, Laird DW. Pathways regulating the trafficking and turnover of pannexin1 protein and the role of the C-terminal domain. The Journal of Biological Chemistry. 286: 27639-53. PMID 21659516 DOI: 10.1074/jbc.M111.260711  0.48
2011 Sosinsky GE, Boassa D, Dermietzel R, Duffy HS, Laird DW, MacVicar B, Naus CC, Penuela S, Scemes E, Spray DC, Thompson RJ, Zhao HB, Dahl G. Pannexin channels are not gap junction hemichannels. Channels (Austin, Tex.). 5: 193-7. PMID 21532340 DOI: 10.4161/Chan.5.3.15765  0.48
2011 Turmel P, Dufresne J, Hermo L, Smith CE, Penuela S, Laird DW, Cyr DG. Characterization of pannexin1 and pannexin3 and their regulation by androgens in the male reproductive tract of the adult rat. Molecular Reproduction and Development. 78: 124-38. PMID 21337450 DOI: 10.1002/mrd.21280  0.48
2011 Churko JM, Shao Q, Gong XQ, Swoboda KJ, Bai D, Sampson J, Laird DW. Human dermal fibroblasts derived from oculodentodigital dysplasia patients suggest that patients may have wound-healing defects. Human Mutation. 32: 456-66. PMID 21305658 DOI: 10.1002/humu.21472  0.48
2011 Tsui E, Hill KA, Laliberte AM, Paluzzi D, Kisilevsky I, Shao Q, Heathcote JG, Laird DW, Kidder GM, Hutnik CM. Ocular pathology relevant to glaucoma in a Gja1(Jrt/+) mouse model of human oculodentodigital dysplasia. Investigative Ophthalmology & Visual Science. 52: 3539-47. PMID 21273537 DOI: 10.1167/iovs.10-6399  0.48
2011 Plante I, Stewart MK, Barr K, Allan AL, Laird DW. Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human disease. Oncogene. 30: 1681-92. PMID 21151177 DOI: 10.1038/onc.2010.551  0.48
2011 Sosinsky GE, Boassa D, Dermietzel R, Duffy HS, Laird DW, MacVicar BA, Naus CC, Penuela S, Scemes E, Spray DC, Thompson RJ, Zhao HB, Dahl G. Pannexin channels are not gap junction hemichannels Channels. 5.  0.48
2010 Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, Isakson BE, Bayliss DA, Ravichandran KS. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature. 467: 863-7. PMID 20944749 DOI: 10.1038/Nature09413  0.48
2010 Churko JM, Langlois S, Pan X, Shao Q, Laird DW. The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants. The Biochemical Journal. 429: 473-83. PMID 20515445 DOI: 10.1042/BJ20100155  0.48
2010 Naus CC, Laird DW. Implications and challenges of connexin connections to cancer. Nature Reviews. Cancer. 10: 435-41. PMID 20495577 DOI: 10.1038/nrc2841  0.48
2010 Langlois S, Cowan KN, Shao Q, Cowan BJ, Laird DW. The tumor-suppressive function of Connexin43 in keratinocytes is mediated in part via interaction with caveolin-1. Cancer Research. 70: 4222-32. PMID 20406988 DOI: 10.1158/0008-5472.CAN-09-3281  0.48
2010 Celetti SJ, Cowan KN, Penuela S, Shao Q, Churko J, Laird DW. Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation. Journal of Cell Science. 123: 1363-72. PMID 20332104 DOI: 10.1242/jcs.056093  0.48
2010 Toth K, Shao Q, Lorentz R, Laird DW. Decreased levels of Cx43 gap junctions result in ameloblast dysregulation and enamel hypoplasia in Gja1Jrt/+ mice. Journal of Cellular Physiology. 223: 601-9. PMID 20127707 DOI: 10.1002/jcp.22046  0.48
2010 Plante I, Wallis A, Shao Q, Laird DW. Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged. Biology of Reproduction. 82: 837-47. PMID 20089884 DOI: 10.1095/biolreprod.109.081406  0.48
2010 Bhalla-Gehi R, Penuela S, Churko JM, Shao Q, Laird DW. Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions. The Journal of Biological Chemistry. 285: 9147-60. PMID 20086016 DOI: 10.1074/jbc.M109.082008  0.48
2009 Simek J, Churko J, Shao Q, Laird DW. Cx43 has distinct mobility within plasma-membrane domains, indicative of progressive formation of gap-junction plaques. Journal of Cell Science. 122: 554-62. PMID 19174466 DOI: 10.1242/jcs.036970  0.48
2008 Manias JL, Plante I, Gong XQ, Shao Q, Churko J, Bai D, Laird DW. Fate of connexin43 in cardiac tissue harbouring a disease-linked connexin43 mutant. Cardiovascular Research. 80: 385-95. PMID 18678643 DOI: 10.1093/cvr/cvn203  0.48
2008 Penuela S, Celetti SJ, Bhalla R, Shao Q, Laird DW. Diverse subcellular distribution profiles of pannexin 1 and pannexin 3. Cell Communication & Adhesion. 15: 133-42. PMID 18649185 DOI: 10.1080/15419060802014115  0.48
2008 McLachlan E, Plante I, Shao Q, Tong D, Kidder GM, Bernier SM, Laird DW. ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 928-38. PMID 18269311 DOI: 10.1359/jbmr.080217  0.48
2008 Hutnik CM, Pocrnich CE, Liu H, Laird DW, Shao Q. The protective effect of functional connexin43 channels on a human epithelial cell line exposed to oxidative stress. Investigative Ophthalmology & Visual Science. 49: 800-6. PMID 18235030 DOI: 10.1167/iovs.07-0717  0.48
2008 Langlois S, Cowan KN, Shao Q, Cowan BJ, Laird DW. Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes. Molecular Biology of the Cell. 19: 912-28. PMID 18162583 DOI: 10.1091/mbc.E07-06-0596  0.48
2007 Penuela S, Bhalla R, Gong XQ, Cowan KN, Celetti SJ, Cowan BJ, Bai D, Shao Q, Laird DW. Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. Journal of Cell Science. 120: 3772-83. PMID 17925379 DOI: 10.1242/jcs.009514  0.48
2007 Langlois S, Maher AC, Manias JL, Shao Q, Kidder GM, Laird DW. Connexin levels regulate keratinocyte differentiation in the epidermis. The Journal of Biological Chemistry. 282: 30171-80. PMID 17693411 DOI: 10.1074/jbc.M703623200  0.48
2007 McLachlan E, Shao Q, Laird DW. Connexins and gap junctions in mammary gland development and breast cancer progression. The Journal of Membrane Biology. 218: 107-21. PMID 17661126 DOI: 10.1007/s00232-007-9052-x  0.48
2007 Thomas T, Shao Q, Laird DW. Differentiation of organotypic epidermis in the presence of skin disease-linked dominant-negative Cx26 mutants and knockdown Cx26. The Journal of Membrane Biology. 217: 93-104. PMID 17638039 DOI: 10.1007/s00232-007-9036-x  0.48
2007 Gong XQ, Shao Q, Langlois S, Bai D, Laird DW. Differential potency of dominant negative connexin43 mutants in oculodentodigital dysplasia. The Journal of Biological Chemistry. 282: 19190-202. PMID 17420259 DOI: 10.1074/jbc.M609653200  0.48
2006 McLachlan E, Shao Q, Wang HL, Langlois S, Laird DW. Connexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis. Cancer Research. 66: 9886-94. PMID 17047050 DOI: 10.1158/0008-5472.CAN-05-4302  0.48
2006 Gong XQ, Shao Q, Lounsbury CS, Bai D, Laird DW. Functional characterization of a GJA1 frameshift mutation causing oculodentodigital dysplasia and palmoplantar keratoderma. The Journal of Biological Chemistry. 281: 31801-11. PMID 16891658 DOI: 10.1074/jbc.M605961200  0.48
2006 Kalra J, Shao Q, Qin H, Thomas T, Alaoui-Jamali MA, Laird DW. Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism. Carcinogenesis. 27: 2528-37. PMID 16777986 DOI: 10.1093/Carcin/Bgl110  0.48
2006 Hernandez M, Shao Q, Yang XJ, Luh SP, Kandouz M, Batist G, Laird DW, Alaoui-Jamali MA. A histone deacetylation-dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells. The Prostate. 66: 1151-61. PMID 16652385 DOI: 10.1002/Pros.20451  0.48
2005 McLachlan E, Manias JL, Gong XQ, Lounsbury CS, Shao Q, Bernier SM, Bai D, Laird DW. Functional characterization of oculodentodigital dysplasia-associated Cx43 mutants. Cell Communication & Adhesion. 12: 279-92. PMID 16531323 DOI: 10.1080/15419060500514143  0.48
2005 Maher AC, Thomas T, Riley JL, Veitch G, Shao Q, Laird DW. Rat epidermal keratinocytes as an organotypic model for examining the role of Cx43 and Cx26 in skin differentiation. Cell Communication & Adhesion. 12: 219-30. PMID 16531317 DOI: 10.1080/15419060500511818  0.48
2005 Thomas T, Jordan K, Simek J, Shao Q, Jedeszko C, Walton P, Laird DW. Mechanisms of Cx43 and Cx26 transport to the plasma membrane and gap junction regeneration. Journal of Cell Science. 118: 4451-62. PMID 16159960 DOI: 10.1242/Jcs.02569  0.48
2005 Flenniken AM, Osborne LR, Anderson N, Ciliberti N, Fleming C, Gittens JE, Gong XQ, Kelsey LB, Lounsbury C, Moreno L, Nieman BJ, Peterson K, Qu D, Roscoe W, Shao Q, ... ... Laird DW, et al. A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (Cambridge, England). 132: 4375-86. PMID 16155213 DOI: 10.1242/Dev.02011  0.48
2005 Pollmann MA, Shao Q, Laird DW, Sandig M. Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture. Breast Cancer Research : Bcr. 7: R522-34. PMID 15987459 DOI: 10.1186/bcr1042  0.48
2005 Shao Q, Wang H, McLachlan E, Veitch GI, Laird DW. Down-regulation of Cx43 by retroviral delivery of small interfering RNA promotes an aggressive breast cancer cell phenotype. Cancer Research. 65: 2705-11. PMID 15805269 DOI: 10.1158/0008-5472.CAN-04-2367  0.48
2005 Roscoe W, Veitch GI, Gong XQ, Pellegrino E, Bai D, McLachlan E, Shao Q, Kidder GM, Laird DW. Oculodentodigital dysplasia-causing connexin43 mutants are non-functional and exhibit dominant effects on wild-type connexin43. The Journal of Biological Chemistry. 280: 11458-66. PMID 15644317 DOI: 10.1074/jbc.M409564200  0.48
2005 Wang X, Ferreira AM, Shao Q, Laird DW, Sandig M. Beta3 integrins facilitate matrix interactions during transendothelial migration of PC3 prostate tumor cells. The Prostate. 63: 65-80. PMID 15468167 DOI: 10.1002/pros.20168  0.48
2004 Veitch GI, Gittens JE, Shao Q, Laird DW, Kidder GM. Selective assembly of connexin37 into heterocellular gap junctions at the oocyte/granulosa cell interface. Journal of Cell Science. 117: 2699-707. PMID 15138288 DOI: 10.1242/jcs.01124  0.48
2004 Thomas T, Telford D, Laird DW. Functional domain mapping and selective trans-dominant effects exhibited by Cx26 disease-causing mutations. The Journal of Biological Chemistry. 279: 19157-68. PMID 14978038 DOI: 10.1074/jbc.M314117200  0.4
2003 Qin H, Shao Q, Thomas T, Kalra J, Alaoui-Jamali MA, Laird DW. Connexin26 regulates the expression of angiogenesis-related genes in human breast tumor cells by both GJIC-dependent and -independent mechanisms. Cell Communication & Adhesion. 10: 387-93. PMID 14681046 DOI: 10.1080/Cac.10.4-6.387.393  0.48
2003 Thomas T, Aasen T, Hodgins M, Laird DW. Transport and function of cx26 mutants involved in skin and deafness disorders. Cell Communication & Adhesion. 10: 353-8. PMID 14681041  0.4
2003 Qin H, Shao Q, Igdoura SA, Alaoui-Jamali MA, Laird DW. Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells. The Journal of Biological Chemistry. 278: 30005-14. PMID 12767974 DOI: 10.1074/Jbc.M300614200  0.48
2002 Qin H, Shao Q, Curtis H, Galipeau J, Belliveau DJ, Wang T, Alaoui-Jamali MA, Laird DW. Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication. The Journal of Biological Chemistry. 277: 29132-8. PMID 12042301 DOI: 10.1074/Jbc.M200797200  0.48
2002 Gaietta G, Deerinck TJ, Adams SR, Bouwer J, Tour O, Laird DW, Sosinsky GE, Tsien RY, Ellisman MH. Multicolor and electron microscopic imaging of connexin trafficking. Science (New York, N.Y.). 296: 503-7. PMID 11964472 DOI: 10.1126/Science.1068793  0.48
2002 Johnson RG, Meyer RA, Li XR, Preus DM, Tan L, Grunenwald H, Paulson AF, Laird DW, Sheridan JD. Gap junctions assemble in the presence of cytoskeletal inhibitors, but enhanced assembly requires microtubules. Experimental Cell Research. 275: 67-80. PMID 11925106 DOI: 10.1006/excr.2002.5480  0.48
2001 Thomas T, Jordan K, Laird DW. Role of cytoskeletal elements in the recruitment of Cx43-GFP and Cx26-YFP into gap junctions. Cell Communication & Adhesion. 8: 231-6. PMID 12064594  0.48
2001 Laird DW, Jordan K, Shao Q. Expression and imaging of connexin-GFP chimeras in live mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 154: 135-42. PMID 11218645  0.48
2001 Laird DW, Jordan K, Thomas T, Qin H, Fistouris P, Shao Q. Comparative analysis and application of fluorescent protein-tagged connexins. Microscopy Research and Technique. 52: 263-72. PMID 11180619 DOI: 10.1002/1097-0029(20010201)52:3<263::AID-JEMT1012>3.0.CO;2-Q  0.48
2001 Huynh HT, Alpert L, Laird DW, Batist G, Chalifour L, Alaoui-Jamali MA. Regulation of the gap junction connexin 43 gene by androgens in the prostate. Journal of Molecular Endocrinology. 26: 1-10. PMID 11174849 DOI: 10.1677/Jme.0.0260001  0.48
2001 Jordan K, Chodock R, Hand AR, Laird DW. The origin of annular junctions: a mechanism of gap junction internalization. Journal of Cell Science. 114: 763-73. PMID 11171382  0.48
2000 Mao AJ, Bechberger J, Lidington D, Galipeau J, Laird DW, Naus CCG. Neuronal differentiation and growth control of neuro-2a cells after retroviral gene delivery of connexin43 Journal of Biological Chemistry. 275: 34407-34414. PMID 10924505  0.48
2000 Bukauskas FF, Jordan K, Bukauskiene A, Bennett MV, Lampe PD, Laird DW, Verselis VK. Clustering of connexin 43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 2556-61. PMID 10706639 DOI: 10.1073/Pnas.050588497  0.48
1999 Caruso JA, Laird DW, Batist G. Role of HSP90 in mediating cross-talk between the estrogen receptor and the Ah receptor signal transduction pathways. Biochemical Pharmacology. 58: 1395-403. PMID 10513983 DOI: 10.1016/S0006-2952(99)00225-7  0.48
1999 Cyr DG, Hermo L, Egenberger N, Mertineit C, Trasler JM, Laird DW. Cellular immunolocalization of occludin during embryonic and postnatal development of the mouse testis and epididymis. Endocrinology. 140: 3815-25. PMID 10433243 DOI: 10.1210/endo.140.8.6903  0.48
1999 Jordan K, Solan JL, Dominguez M, Sia M, Hand A, Lampe PD, Laird DW. Trafficking, assembly, and function of a connexin43-green fluorescent protein chimera in live mammalian cells. Molecular Biology of the Cell. 10: 2033-50. PMID 10359613 DOI: 10.1091/Mbc.10.6.2033  0.48
1997 Xie HQ, Laird DW, Chang TH, Hu VW. A mitosis-specific phosphorylation of the gap junction protein connexin43 in human vascular cells: Biochemical characterization and localization Journal of Cell Biology. 137: 203-210. PMID 9105048 DOI: 10.1083/jcb.137.1.203  0.48
1997 Feldman PA, Kim J, Laird DW. Loss of gap junction plaques and inhibition of intercellular communication in ilimaquinone-treated BICR-M1Rk and NRK cells. The Journal of Membrane Biology. 155: 275-87. PMID 9050451 DOI: 10.1007/s002329900180  0.48
1996 Cyr DG, Hermo L, Laird DW. Immunocytochemical localization and regulation of connexin43 in the adult rat epididymis. Endocrinology. 137: 1474-84. PMID 8625926 DOI: 10.1210/endo.137.4.8625926  0.48
1993 Puranam KL, Laird DW, Revel JP. Trapping an intermediate form of connexin43 in the Golgi. Experimental Cell Research. 206: 85-92. PMID 8387024 DOI: 10.1006/excr.1993.1123  0.48
1993 Lal R, Laird DW, Revel JP. Antibody perturbation analysis of gap-junction permeability in rat cardiac myocytes. PflüGers Archiv : European Journal of Physiology. 422: 449-57. PMID 7682685 DOI: 10.1007/BF00375070  0.48
1992 Reid DM, Laird DW, Molday RS. Characterization and application of an in vitro detection system for studying the binding and phagocytosis of rod outer segments by retinal pigment epithelial cells Experimental Eye Research. 54: 775-783. PMID 1623963 DOI: 10.1016/0014-4835(92)90033-O  0.48
1992 Laird DW, Yancey SB, Bugga L, Revel JP. Connexin expression and gap junction communication compartments in the developing mouse limb. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 195: 153-61. PMID 1338686 DOI: 10.1002/aja.1001950302  0.48
1992 Meyer RA, Laird DW, Revel JP, Johnson RG. Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies. The Journal of Cell Biology. 119: 179-89. PMID 1326565  0.48
1991 Laird DW, Puranam KL, Revel JP. Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes. The Biochemical Journal. 273: 67-72. PMID 1846532  0.48
1991 Yahalom A, Warmbrodt RD, Laird DW, Traub O, Revel JP, Willecke K, Epel BL. Maize mesocotyl plasmodesmata proteins cross-react with connexin gap junction protein antibodies. The Plant Cell. 3: 407-17. PMID 1668654 DOI: 10.1105/tpc.3.4.407  0.48
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