Stephen Sims - Publications

Affiliations: 
The University of Western Ontario (Canada) 
Area:
Cell Biology

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Beaucage KL, Pollmann SI, Sims SM, Dixon SJ, Holdsworth DW. Quantitative in vivo micro-computed tomography for assessment of age-dependent changes in murine whole-body composition. Bone Reports. 5: 70-80. PMID 28326349 DOI: 10.1016/j.bonr.2016.04.002  0.56
2016 Lorusso D, Nikolov HN, Milner JS, Ochotny NM, Sims SM, Dixon SJ, Holdsworth DW. Practical fabrication of microfluidic platforms for live-cell microscopy. Biomedical Microdevices. 18: 78. PMID 27523472 DOI: 10.1007/s10544-016-0101-z  0.32
2016 Zhang L, Lu X, Gui L, Wu Y, Sims SM, Wang G, Feng Q. Inhibition of Rac1 reduces store overload-induced calcium release and protects against ventricular arrhythmia. Journal of Cellular and Molecular Medicine. PMID 27222313 DOI: 10.1111/jcmm.12840  0.32
2014 Beaucage KL, Xiao A, Pollmann SI, Grol MW, Beach RJ, Holdsworth DW, Sims SM, Darling MR, Dixon SJ. Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice. Purinergic Signalling. 10: 291-304. PMID 24222214 DOI: 10.1007/s11302-013-9388-x  0.32
2014 Wheal BD, Beach RJ, Tanabe N, Dixon SJ, Sims SM. Subcellular elevation of cytosolic free calcium is required for osteoclast migration. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 725-34. PMID 23956003 DOI: 10.1002/jbmr.2068  0.56
2013 Shugg RP, Thomson A, Tanabe N, Kashishian A, Steiner BH, Puri KD, Pereverzev A, Lannutti BJ, Jirik FR, Dixon SJ, Sims SM. Effects of isoform-selective phosphatidylinositol 3-kinase inhibitors on osteoclasts: actions on cytoskeletal organization, survival, and resorption. The Journal of Biological Chemistry. 288: 35346-57. PMID 24133210 DOI: 10.1074/jbc.M113.507525  0.32
2013 Costa DO, Prowse PD, Chrones T, Sims SM, Hamilton DW, Rizkalla AS, Dixon SJ. The differential regulation of osteoblast and osteoclast activity by surface topography of hydroxyapatite coatings. Biomaterials. 34: 7215-26. PMID 23830579 DOI: 10.1016/j.biomaterials.2013.06.014  0.32
2013 Grol MW, Pereverzev A, Sims SM, Dixon SJ. P2 receptor networks regulate signaling duration over a wide dynamic range of ATP concentrations. Journal of Cell Science. 126: 3615-26. PMID 23750003 DOI: 10.1242/jcs.122705  0.32
2013 Reyes JP, Grol MW, Sims SM, Dixon SJ. Receptor-independent effects of 2'(3')-O-(4-benzoylbenzoyl)ATP triethylammonium salt on cytosolic pH. Purinergic Signalling. 9: 687-93. PMID 23689980 DOI: 10.1007/s11302-013-9365-4  0.32
2013 Durand M, Komarova SV, Bhargava A, Trebec-Reynolds DP, Li K, Fiorino C, Maria O, Nabavi N, Manolson MF, Harrison RE, Dixon SJ, Sims SM, Mizianty MJ, Kurgan L, Haroun S, et al. Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro Osteoclast Differentiation in Arthritis study. Arthritis and Rheumatism. 65: 148-58. PMID 23044761 DOI: 10.1002/art.37722  0.32
2013 Sims SM, Panupinthu N, Lapierre DM, Pereverzev A, Dixon SJ. Lysophosphatidic acid: a potential mediator of osteoblast-osteoclast signaling in bone. Biochimica Et Biophysica Acta. 1831: 109-16. PMID 22892679 DOI: 10.1016/j.bbalip.2012.08.001  0.32
2011 Tanabe N, Wheal BD, Kwon J, Chen HH, Shugg RP, Sims SM, Goldberg HA, Dixon SJ. Osteopontin signals through calcium and nuclear factor of activated T cells (NFAT) in osteoclasts: a novel RGD-dependent pathway promoting cell survival. The Journal of Biological Chemistry. 286: 39871-81. PMID 21940634 DOI: 10.1074/jbc.M111.295048  0.56
2011 Reyes JP, Sims SM, Dixon SJ. P2 receptor expression, signaling and function in osteoclasts. Frontiers in Bioscience (Scholar Edition). 3: 1101-18. PMID 21622259  0.56
2010 Lapierre DM, Tanabe N, Pereverzev A, Spencer M, Shugg RP, Dixon SJ, Sims SM. Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival. The Journal of Biological Chemistry. 285: 25792-801. PMID 20551326 DOI: 10.1074/jbc.M110.109322  0.32
2009 Grol MW, Panupinthu N, Korcok J, Sims SM, Dixon SJ. Expression, signaling, and function of P2X7 receptors in bone. Purinergic Signalling. 5: 205-21. PMID 19224395 DOI: 10.1007/s11302-009-9139-1  0.32
2009 Armstrong S, Pereverzev A, Dixon SJ, Sims SM. Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts. Journal of Cell Science. 122: 136-44. PMID 19066285 DOI: 10.1242/jcs.031534  0.32
2008 Panupinthu N, Rogers JT, Zhao L, Solano-Flores LP, Possmayer F, Sims SM, Dixon SJ. P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis. The Journal of Cell Biology. 181: 859-71. PMID 18519738 DOI: 10.1083/jcb.200708037  0.32
2008 Kovac JR, Chrones T, Sims SM. Temporal and spatial dynamics underlying capacitative calcium entry in human colonic smooth muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G88-98. PMID 17975132 DOI: 10.1152/ajpgi.00305.2007  0.32
2008 Pereverzev A, Komarova SV, Korcok J, Armstrong S, Tremblay GB, Dixon SJ, Sims SM. Extracellular acidification enhances osteoclast survival through an NFAT-independent, protein kinase C-dependent pathway. Bone. 42: 150-61. PMID 17964236 DOI: 10.1016/j.bone.2007.08.044  0.32
2007 Armstrong S, Korcok J, Sims SM, Dixon SJ. Activation of transcription factors by extracellular nucleotides in immune and related cell types. Purinergic Signalling. 3: 59-69. PMID 18404419 DOI: 10.1007/s11302-006-9037-8  0.56
2007 Gramoun A, Shorey S, Bashutski JD, Dixon SJ, Sims SM, Heersche JN, Manolson MF. Effects of Vitaxin, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro. Journal of Cellular Biochemistry. 102: 341-52. PMID 17390341 DOI: 10.1002/jcb.21296  0.32
2007 Panupinthu N, Zhao L, Possmayer F, Ke HZ, Sims SM, Dixon SJ. P2X7 nucleotide receptors mediate blebbing in osteoblasts through a pathway involving lysophosphatidic acid. The Journal of Biological Chemistry. 282: 3403-12. PMID 17135244 DOI: 10.1074/jbc.M605620200  0.32
2006 Kovac JR, Chrones T, Preiksaitis HG, Sims SM. Tachykinin receptor expression and function in human esophageal smooth muscle. The Journal of Pharmacology and Experimental Therapeutics. 318: 513-20. PMID 16714401 DOI: 10.1124/jpet.106.104034  0.32
2006 Jones DH, Nakashima T, Sanchez OH, Kozieradzki I, Komarova SV, Sarosi I, Morony S, Rubin E, Sarao R, Hojilla CV, Komnenovic V, Kong YY, Schreiber M, Dixon SJ, Sims SM, et al. Regulation of cancer cell migration and bone metastasis by RANKL. Nature. 440: 692-6. PMID 16572175 DOI: 10.1038/nature04524  0.32
2005 Yaghi A, Sims SM. Constrictor-induced translocation of NFAT3 in human and rat pulmonary artery smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L1061-74. PMID 16055480 DOI: 10.1152/ajplung.00096.2005  0.32
2005 Kovac JR, Preiksaitis HG, Sims SM. Functional and molecular analysis of L-type calcium channels in human esophagus and lower esophageal sphincter smooth muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G998-1006. PMID 16020652 DOI: 10.1152/ajpgi.00529.2004  0.32
2005 Korcok J, Raimundo LN, Du X, Sims SM, Dixon SJ. P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts. The Journal of Biological Chemistry. 280: 16909-15. PMID 15722352 DOI: 10.1074/jbc.M410764200  0.56
2005 Komarova SV, Pereverzev A, Shum JW, Sims SM, Dixon SJ. Convergent signaling by acidosis and receptor activator of NF-kappaB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts. Proceedings of the National Academy of Sciences of the United States of America. 102: 2643-8. PMID 15695591 DOI: 10.1073/pnas.0406874102  0.32
2005 Williams BA, Liu C, Deyoung L, Brock GB, Sims SM. Regulation of intracellular Ca2+ release in corpus cavernosum smooth muscle: synergism between nitric oxide and cGMP. American Journal of Physiology. Cell Physiology. 288: C650-8. PMID 15537706 DOI: 10.1152/ajpcell.00475.2004  0.44
2004 Korcok J, Raimundo LN, Ke HZ, Sims SM, Dixon SJ. Extracellular nucleotides act through P2X7 receptors to activate NF-kappaB in osteoclasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 642-51. PMID 15005852 DOI: 10.1359/JBMR.040108  0.56
2003 Komarova SV, Smith RJ, Dixon SJ, Sims SM, Wahl LM. Mathematical model predicts a critical role for osteoclast autocrine regulation in the control of bone remodeling. Bone. 33: 206-15. PMID 14499354 DOI: 10.1016/S8756-3282(03)00157-1  0.32
2003 Ke HZ, Qi H, Weidema AF, Zhang Q, Panupinthu N, Crawford DT, Grasser WA, Paralkar VM, Li M, Audoly LP, Gabel CA, Jee WS, Dixon SJ, Sims SM, Thompson DD. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Molecular Endocrinology (Baltimore, Md.). 17: 1356-67. PMID 12677010 DOI: 10.1210/me.2003-0021  0.56
2003 Karkanis T, Li S, Pickering JG, Sims SM. Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery. American Journal of Physiology. Heart and Circulatory Physiology. 284: H2325-34. PMID 12598232 DOI: 10.1152/ajpheart.00559.2002  0.44
2003 Komarova SV, Pilkington MF, Weidema AF, Dixon SJ, Sims SM. RANK ligand-induced elevation of cytosolic Ca2+ accelerates nuclear translocation of nuclear factor kappa B in osteoclasts. The Journal of Biological Chemistry. 278: 8286-93. PMID 12496256 DOI: 10.1074/jbc.M206421200  0.32
2003 Karkanis T, DeYoung L, Brock GB, Sims SM. Ca2+-activated Cl- channels in corpus cavernosum smooth muscle: a novel mechanism for control of penile erection. Journal of Applied Physiology (Bethesda, Md. : 1985). 94: 301-13. PMID 12391071 DOI: 10.1152/japplphysiol.00660.2002  0.44
2001 Naemsch LN, Dixon SJ, Sims SM. Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts. The Journal of Biological Chemistry. 276: 39107-14. PMID 11495918 DOI: 10.1074/jbc.M105881200  0.56
2001 Pilkington MF, Sims SM, Dixon SJ. Transforming growth factor-beta induces osteoclast ruffling and chemotaxis: potential role in osteoclast recruitment. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 16: 1237-47. PMID 11450699 DOI: 10.1359/jbmr.2001.16.7.1237  0.56
2001 Karkanis T, Jiao Y, Hurley BR, Li S, Pickering JG, Sims SM. Functional receptor-channel coupling compared in contractile and proliferative human vascular smooth muscle. Journal of Cellular Physiology. 187: 244-55. PMID 11268004 DOI: 10.1002/jcp.1069  0.44
1999 Naemsch LN, Weidema AF, Sims SM, Underhill TM, Dixon SJ. P2X(4) purinoceptors mediate an ATP-activated, non-selective cation current in rabbit osteoclasts. Journal of Cell Science. 112: 4425-35. PMID 10564660  0.56
1999 Nakamura I, Pilkington MF, Lakkakorpi PT, Lipfert L, Sims SM, Dixon SJ, Rodan GA, Duong LT. Role of alpha(v)beta(3) integrin in osteoclast migration and formation of the sealing zone. Journal of Cell Science. 112: 3985-93. PMID 10547359  0.56
1998 Pilkington MF, Sims SM, Dixon SJ. Wortmannin inhibits spreading and chemotaxis of rat osteoclasts in vitro. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 13: 688-94. PMID 9556069 DOI: 10.1359/jbmr.1998.13.4.688  0.56
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