Richard Loeser - Publications

Affiliations: 
Rush University, Chicago, IL, United States 
Area:
Cell Biology, Pathology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Armstrong AR, Carlson CS, Rendahl AK, Loeser RF. Optimization of histologic grading schemes in spontaneous and surgically-induced murine models of osteoarthritis. Osteoarthritis and Cartilage. PMID 33561541 DOI: 10.1016/j.joca.2021.01.006  0.48
2020 Loeser RF, Collins JA, Diekman BO, Carlson CS. Reply. Arthritis & Rheumatology (Hoboken, N.J.). 72: 2162-2163. PMID 33459503 DOI: 10.1002/art.41431  0.48
2020 Loeser RF, Kelley KL, Armstrong A, Collins JA, Diekman BO, Carlson CS. Deletion of c-Jun N-terminal Kinase Enhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32418287 DOI: 10.1002/art.41312  0.48
2019 Ewart D, Harper L, Gravely A, Miller RA, Carlson CS, Loeser RF. Naturally occurring osteoarthritis in male mice with an extended lifespan. Connective Tissue Research. 1-9. PMID 31530037 DOI: 10.1080/03008207.2019.1635590  0.48
2018 Diekman BO, Sessions GA, Collins JA, Knecht AK, Strum SL, Mitin NK, Carlson CS, Loeser RF, Sharpless NE. Expression of p16 is a biomarker of chondrocyte aging but does not cause osteoarthritis. Aging Cell. e12771. PMID 29744983 DOI: 10.1111/acel.12771  0.48
2016 Rowe MA, Harper LR, McNulty MA, Lau AG, Carlson CS, Leng L, Bucala RJ, Miller RA, Loeser RF. Deletion of Macrophage Migration Inhibitory Factor Reduces Severity of Osteoarthritis in Aged Mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27564840 DOI: 10.1002/art.39844  0.48
2016 Loeser RF, Pathmasiri W, Sumner SJ, McRitchie S, Beavers D, Saxena P, Nicklas BJ, Jordan J, Guermazi A, Hunter DJ, Messier SP. Association of Urinary Metabolites with Radiographic Progression of Knee Osteoarthritis in Overweight and Obese Adults: An Exploratory Study. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 27012755 DOI: 10.1016/j.joca.2016.03.011  0.48
2016 Collins JA, Wood ST, Nelson KJ, Rowe MA, Carlson CS, Chubinskaya S, Poole LB, Furdui CM, Loeser RF. Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signalling in Aging Chondrocytes. The Journal of Biological Chemistry. PMID 26797130 DOI: 10.1074/jbc.M115.693523  0.48
2016 Vanderman KS, Loeser RF, Chubinskaya S, Anderson A, Ferguson CM. Reduced Response of Human Meniscal Cells to Osteogenic Protein 1 during Osteoarthritis and Pro-inflammatory Stimulation. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 26778533 DOI: 10.1016/j.joca.2015.12.017  0.48
2015 Shea MK, Loeser RF, Hsu FC, Booth SL, Nevitt M, Simonsick EM, Strotmeyer ES, Vermeer C, Kritchevsky SB. Vitamin K Status and Lower Extremity Function in Older Adults: The Health Aging and Body Composition Study. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26576842 DOI: 10.1093/gerona/glv209  0.48
2015 Greene MA, Loeser RF. Aging-related inflammation in osteoarthritis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 1966-71. PMID 26521742 DOI: 10.1016/j.joca.2015.01.008  0.48
2015 Wood ST, Long DL, Reisz JA, Yammani RR, Burke EA, Klomsiri C, Poole LB, Furdui CM, Loeser RF. Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated with Fibronectin Fragments. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26314228 DOI: 10.1002/art.39326  0.48
2015 Stone AV, Vanderman KS, Willey JS, Long DL, Register TC, Shively CA, Stehle JR, Loeser RF, Ferguson CM. Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 26033163 DOI: 10.1016/j.joca.2015.05.020  0.48
2015 Long DL, Ulici V, Chubinskaya S, Loeser RF. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 1523-31. PMID 25937027 DOI: 10.1016/j.joca.2015.04.019  0.48
2015 Hunter DJ, Beavers DP, Eckstein F, Guermazi A, Loeser RF, Nicklas BJ, Mihalko SL, Miller GD, Lyles M, DeVita P, Legault C, Carr JJ, Williamson JD, Messier SP. The Intensive Diet and Exercise for Arthritis (IDEA) trial: 18-month radiographic and MRI outcomes. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 1090-8. PMID 25887362 DOI: 10.1016/j.joca.2015.03.034  0.48
2015 Greene MA, Loeser RF. Function of the chondrocyte PI-3 kinase-Akt signaling pathway is stimulus dependent. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 949-56. PMID 25659655 DOI: 10.1016/j.joca.2015.01.014  0.48
2015 Shea MK, Kritchevsky SB, Hsu FC, Nevitt M, Booth SL, Kwoh CK, McAlindon TE, Vermeer C, Drummen N, Harris TB, Womack C, Loeser RF. The association between vitamin K status and knee osteoarthritis features in older adults: the Health, Aging and Body Composition Study. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 370-8. PMID 25528106 DOI: 10.1016/j.joca.2014.12.008  0.48
2015 Beavers KM, Beavers DP, Newman JJ, Anderson AM, Loeser RF, Nicklas BJ, Lyles MF, Miller GD, Mihalko SL, Messier SP. Effects of total and regional fat loss on plasma CRP and IL-6 in overweight and obese, older adults with knee osteoarthritis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 249-56. PMID 25450847 DOI: 10.1016/j.joca.2014.11.005  0.48
2015 Hobbs GA, Mitchell LE, Arrington ME, Gunawardena HP, DeCristo MJ, Loeser RF, Chen X, Cox AD, Campbell SL. Redox regulation of Rac1 by thiol oxidation. Free Radical Biology & Medicine. 79: 237-50. PMID 25289457 DOI: 10.1016/j.freeradbiomed.2014.09.027  0.48
2015 Loeser RF, Lotz M. Osteoarthritis in the Elderly Advances in Geroscience. 309-353. DOI: 10.1007/978-3-319-23246-1_11  0.48
2015 Loeser RF, Ferguson CM, Lotz MK. Aging and post-traumatic arthritis Post-Traumatic Arthritis: Pathogenesis, Diagnosis and Management. 165-183. DOI: 10.1007/978-1-4899-7606-2_14  0.48
2014 Messier SP, Beavers DP, Loeser RF, Carr JJ, Khajanchi S, Legault C, Nicklas BJ, Hunter DJ, Devita P. Knee joint loading in knee osteoarthritis: influence of abdominal and thigh fat. Medicine and Science in Sports and Exercise. 46: 1677-83. PMID 25133996 DOI: 10.1249/MSS.0000000000000293  0.48
2014 Messier SP, Pater M, Beavers DP, Legault C, Loeser RF, Hunter DJ, DeVita P. Influences of alignment and obesity on knee joint loading in osteoarthritic gait. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 912-7. PMID 24857973 DOI: 10.1016/j.joca.2014.05.013  0.48
2014 Beavers DP, Beavers KM, Loeser RF, Walton NR, Lyles MF, Nicklas BJ, Shapses SA, Newman JJ, Messier SP. The independent and combined effects of intensive weight loss and exercise training on bone mineral density in overweight and obese older adults with osteoarthritis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 726-33. PMID 24742955 DOI: 10.1016/j.joca.2014.04.002  0.48
2014 Loeser RF, Gandhi U, Long DL, Yin W, Chubinskaya S. Aging and oxidative stress reduce the response of human articular chondrocytes to insulin-like growth factor 1 and osteogenic protein 1. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2201-9. PMID 24664641 DOI: 10.1002/art.38641  0.48
2014 Stone AV, Loeser RF, Vanderman KS, Long DL, Clark SC, Ferguson CM. Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis pathogenesis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 264-74. PMID 24315792 DOI: 10.1016/j.joca.2013.11.002  0.48
2013 Messier SP, Mihalko SL, Legault C, Miller GD, Nicklas BJ, DeVita P, Beavers DP, Hunter DJ, Lyles MF, Eckstein F, Williamson JD, Carr JJ, Guermazi A, Loeser RF. Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial. Jama. 310: 1263-73. PMID 24065013 DOI: 10.1001/jama.2013.277669  0.48
2013 Messier SP, Mihalko SL, Beavers DP, Nicklas BJ, DeVita P, Carr JJ, Hunter DJ, Williamson JD, Bennell KL, Guermazi A, Lyles M, Loeser RF. Strength Training for Arthritis Trial (START): design and rationale. Bmc Musculoskeletal Disorders. 14: 208. PMID 23855596 DOI: 10.1186/1471-2474-14-208  0.48
2013 Long DL, Willey JS, Loeser RF. Rac1 is required for matrix metalloproteinase 13 production by chondrocytes in response to fibronectin fragments. Arthritis and Rheumatism. 65: 1561-8. PMID 23460186 DOI: 10.1002/art.37922  0.48
2013 Loeser RF, Olex AL, McNulty MA, Carlson CS, Callahan M, Ferguson C, Fetrow JS. Disease progression and phasic changes in gene expression in a mouse model of osteoarthritis. Plos One. 8: e54633. PMID 23382930 DOI: 10.1371/journal.pone.0054633  0.48
2013 Willey JS, Long DL, Vanderman KS, Loeser RF. Ionizing radiation causes active degradation and reduces matrix synthesis in articular cartilage. International Journal of Radiation Biology. 89: 268-77. PMID 23134087 DOI: 10.3109/09553002.2013.747015  0.48
2012 McNulty MA, Loeser RF, Davey C, Callahan MF, Ferguson CM, Carlson CS. Histopathology of naturally occurring and surgically induced osteoarthritis in mice. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 20: 949-56. PMID 22595226 DOI: 10.1016/j.joca.2012.05.001  0.48
2012 Lotz M, Loeser RF. Effects of aging on articular cartilage homeostasis. Bone. 51: 241-8. PMID 22487298 DOI: 10.1016/j.bone.2012.03.023  0.48
2012 Loeser RF, Goldring SR, Scanzello CR, Goldring MB. Osteoarthritis: a disease of the joint as an organ. Arthritis and Rheumatism. 64: 1697-707. PMID 22392533 DOI: 10.1002/art.34453  0.48
2012 Loeser RF, Olex AL, McNulty MA, Carlson CS, Callahan MF, Ferguson CM, Chou J, Leng X, Fetrow JS. Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice. Arthritis and Rheumatism. 64: 705-17. PMID 21972019 DOI: 10.1002/art.33388  0.48
2011 McNulty MA, Loeser RF, Davey C, Callahan MF, Ferguson CM, Carlson CS. A Comprehensive Histological Assessment of Osteoarthritis Lesions in Mice. Cartilage. 2: 354-63. PMID 26069594 DOI: 10.1177/1947603511402665  0.48
2011 Ruiz J, Wallace EL, Miller DP, Loeser RF, Miles M, Dubose TD, Lichstein PR. A comprehensive 3-year internal medicine residency research curriculum. The American Journal of Medicine. 124: 469-73. PMID 21531238 DOI: 10.1016/j.amjmed.2011.01.006  0.48
2011 Chubinskaya S, Otten L, Soeder S, Borgia JA, Aigner T, Rueger DC, Loeser RF. Regulation of chondrocyte gene expression by osteogenic protein-1. Arthritis Research & Therapy. 13: R55. PMID 21447156 DOI: 10.1186/ar3300  0.48
2010 Long DL, Loeser RF. p38gamma mitogen-activated protein kinase suppresses chondrocyte production of MMP-13 in response to catabolic stimulation. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 18: 1203-10. PMID 20633667 DOI: 10.1016/j.joca.2010.05.016  0.48
2009 Yin W, Park JI, Loeser RF. Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-kinase-Akt and MEK-ERK MAPK signaling pathways Journal of Biological Chemistry. 284: 31972-31981. PMID 19762915 DOI: 10.1074/jbc.M109.056838  0.48
2009 Messier SP, Legault C, Mihalko S, Miller GD, Loeser RF, DeVita P, Lyles M, Eckstein F, Hunter DJ, Williamson JD, Nicklas BJ. The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale. Bmc Musculoskeletal Disorders. 10: 93. PMID 19638215 DOI: 10.1186/1471-2474-10-93  0.48
2009 Sevick MA, Miller GD, Loeser RF, Williamson JD, Messier SP. Cost-effectiveness of exercise and diet in overweight and obese adults with knee osteoarthritis Medicine and Science in Sports and Exercise. 41: 1167-1174. PMID 19461553 DOI: 10.1249/MSS.0b013e318197ece7  0.48
2009 Cravero JD, Carlson CS, Im HJ, Yammani RR, Long D, Loeser RF. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis. Arthritis and Rheumatism. 60: 492-500. PMID 19180501 DOI: 10.1002/art.24225  0.48
2008 Loeser RF, Erickson EA, Long DL. Mitogen-activated protein kinases as therapeutic targets in osteoarthritis. Current Opinion in Rheumatology. 20: 581-6. PMID 18698181 DOI: 10.1097/BOR.0b013e3283090463  0.48
2008 Del Carlo M, Loeser RF. Cell death in osteoarthritis. Current Rheumatology Reports. 10: 37-42. PMID 18457610  1
2008 Chua SD, Messier SP, Legault C, Lenz ME, Thonar EJMA, Loeser RF. Effect of an exercise and dietary intervention on serum biomarkers in overweight and obese adults with osteoarthritis of the knee Osteoarthritis and Cartilage. 16: 1047-1053. PMID 18359648 DOI: 10.1016/j.joca.2008.02.002  0.48
2008 Miller GD, Nicklas BJ, Loeser RF. Inflammatory biomarkers and physical function in older, obese adults with knee pain and self-reported osteoarthritis after intensive weight-loss therapy. Journal of the American Geriatrics Society. 56: 644-51. PMID 18312558 DOI: 10.1111/j.1532-5415.2007.01636.x  0.48
2007 Messier SP, Mihalko S, Loeser RF, Legault C, Jolla J, Pfruender J, Prosser B, Adrian A, Williamson JD. Glucosamine/chondroitin combined with exercise for the treatment of knee osteoarthritis: a preliminary study Osteoarthritis and Cartilage. 15: 1256-1266. PMID 17561418 DOI: 10.1016/j.joca.2007.04.016  0.48
2007 Del Carlo M, Schwartz D, Erickson EA, Loeser RF. Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments. Free Radical Biology & Medicine. 42: 1350-8. PMID 17395008 DOI: 10.1016/j.freeradbiomed.2007.01.035  0.48
2007 Gilchrist CL, Chen J, Richardson WJ, Loeser RF, Setton LA. Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 25: 829-40. PMID 17318895 DOI: 10.1002/jor.20343  0.48
2007 Im HJ, Muddasani P, Natarajan V, Schmid TM, Block JA, Davis F, van Wijnen AJ, Loeser RF. Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes. The Journal of Biological Chemistry. 282: 11110-21. PMID 17311929 DOI: 10.1074/jbc.M609040200  0.48
2007 Chubinskaya S, Hakimiyan A, Pacione C, Yanke A, Rappoport L, Aigner T, Rueger DC, Loeser RF. Synergistic effect of IGF-1 and OP-1 on matrix formation by normal and OA chondrocytes cultured in alginate beads. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 15: 421-30. PMID 17126570 DOI: 10.1016/j.joca.2006.10.004  0.48
2007 Allen EE, Diao L, Fetrow JS, John DJ, Loeser RF, Poole LB. The shuffle index and evaluation of models of signal transduction pathways Proceedings of the Annual Southeast Conference. 2007: 250-255. DOI: 10.1145/1233341.1233386  0.48
2006 Ekenstedt KJ, Sonntag WE, Loeser RF, Lindgren BR, Carlson CS. Effects of chronic growth hormone and insulin-like growth factor 1 deficiency on osteoarthritis severity in rat knee joints. Arthritis and Rheumatism. 54: 3850-8. PMID 17133593 DOI: 10.1002/art.22254  0.48
2006 Yammani RR, Carlson CS, Bresnick AR, Loeser RF. Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products. Arthritis and Rheumatism. 54: 2901-11. PMID 16948116 DOI: 10.1002/art.22042  0.48
2006 Miller GD, Nicklas BJ, Davis C, Loeser RF, Lenchik L, Messier SP. Intensive weight loss program improves physical function in older obese adults with knee osteoarthritis. Obesity (Silver Spring, Md.). 14: 1219-30. PMID 16899803 DOI: 10.1038/oby.2006.139  0.48
2005 Forsyth CB, Cole A, Murphy G, Bienias JL, Im HJ, Loeser RF. Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 1118-24. PMID 16183949  0.48
2005 Loeser RF, Yammani RR, Carlson CS, Chen H, Cole A, Im HJ, Bursch LS, Yan SD. Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. Arthritis and Rheumatism. 52: 2376-85. PMID 16052547 DOI: 10.1002/art.21199  0.48
2005 Pulai JI, Chen H, Im HJ, Kumar S, Hanning C, Hegde PS, Loeser RF. NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments. Journal of Immunology (Baltimore, Md. : 1950). 174: 5781-8. PMID 15843581 DOI: 10.4049/jimmunol.174.9.5781  0.56
2005 Starkman BG, Cravero JD, Delcarlo M, Loeser RF. IGF-I stimulation of proteoglycan synthesis by chondrocytes requires activation of the PI 3-kinase pathway but not ERK MAPK. The Biochemical Journal. 389: 723-9. PMID 15801908 DOI: 10.1042/BJ20041636  0.48
2005 Sonntag WE, Carter CS, Ikeno Y, Ekenstedt K, Carlson CS, Loeser RF, Chakrabarty S, Lee S, Bennett C, Ingram R, Moore T, Ramsey M. Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span. Endocrinology. 146: 2920-32. PMID 15790724 DOI: 10.1210/en.2005-0058  0.48
2004 Miller GD, Nicklas BJ, Davis CC, Ambrosius WT, Loeser RF, Messier SP. Is serum leptin related to physical function and is it modifiable through weight loss and exercise in older adults with knee osteoarthritis? International Journal of Obesity. 28: 1383-1390. PMID 15278105 DOI: 10.1038/sj.ijo.0802737  0.48
2004 Messier SP, Loeser RF, Miller GD, Morgan TM, Rejeski WJ, Sevick MA, Ettinger WH, Pahor M, Williamson JD. Exercise and Dietary Weight Loss in Overweight and Obese Older Adults with Knee Osteoarthritis: The Arthritis, Diet, and Activity Promotion Trial Arthritis and Rheumatism. 50: 1501-1510. PMID 15146420 DOI: 10.1002/art.20256  0.48
2004 Nicklas BJ, Ambrosius W, Messier SP, Miller GD, Penninx BWJH, Loeser RF, Palla S, Bleecker E, Pahor M. Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: A randomized controlled clinical trial American Journal of Clinical Nutrition. 79: 544-551. PMID 15051595 DOI: 10.1093/ajcn/79.4.544  0.48
2004 Ham KD, Oegema TR, Loeser RF, Carlson CS. Effects of long-term estrogen replacement therapy on articular cartilage IGFBP-2, IGFBP-3, collagen and proteoglycan levels in ovariectomized cynomolgus monkeys. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 12: 160-8. PMID 14723875 DOI: 10.1016/j.joca.2003.08.002  0.48
2003 Miller GD, Rejeski WJ, Williamson JD, Morgan T, Sevick MA, Loeser RF, Ettinger WH, Messier SP. The Arthritis, Diet and Activity Promotion Trial (ADAPT): Design, rationale, and baseline results Controlled Clinical Trials. 24: 462-480. PMID 12865040 DOI: 10.1016/S0197-2456(03)00063-1  0.48
2003 Kurtis MS, Schmidt TA, Bugbee WD, Loeser RF, Sah RL. Integrin-mediated adhesion of human articular chondrocytes to cartilage. Arthritis and Rheumatism. 48: 110-8. PMID 12528111 DOI: 10.1002/art.10704  0.48
2002 Loeser RF, Carlson CS, Del Carlo M, Cole A. Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1. Arthritis and Rheumatism. 46: 2349-57. PMID 12355482 DOI: 10.1002/art.10496  0.48
2002 Ham KD, Loeser RF, Lindgren BR, Carlson CS. Effects of long-term estrogen replacement therapy on osteoarthritis severity in cynomolgus monkeys. Arthritis and Rheumatism. 46: 1956-64. PMID 12124881 DOI: 10.1002/art.10406  0.48
2002 Pulai JI, Del Carlo M, Loeser RF. The alpha5beta1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro. Arthritis and Rheumatism. 46: 1528-35. PMID 12115183 DOI: 10.1002/art.10334  1
2002 Knudson W, Loeser RF. CD44 and integrin matrix receptors participate in cartilage homeostasis Cellular and Molecular Life Sciences. 59: 36-44. PMID 11846031 DOI: 10.1007/s00018-002-8403-0  0.48
2002 Del Carlo M, Loeser RF. Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. Arthritis and Rheumatism. 46: 394-403. PMID 11840442 DOI: 10.1002/art.10056  1
2001 Kurtis MS, Tu BP, Gaya OA, Mollenhauer J, Knudson W, Loeser RF, Knudson CB, Sah RL. Mechanisms of chondrocyte adhesion to cartilage: role of beta1-integrins, CD44, and annexin V. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 19: 1122-30. PMID 11781014 DOI: 10.1016/S0736-0266(01)00051-1  0.48
2001 Miller ME, Jack Rejeski W, Messier SP, Loeser RF. Modifiers of change in physical functioning in older adults with knee pain: The Observational Arthritis Study in Seniors (OASIS) Arthritis Care and Research. 45: 331-339. PMID 11501720 DOI: 10.1002/1529-0131(200108)45:4<331::AID-ART345>3.0.CO;2-6  0.48
2000 Loeser RF, Shanker G, Carlson CS, Gardin JF, Shelton BJ, Sonntag WE. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease. Arthritis and Rheumatism. 43: 2110-20. PMID 11014363 DOI: 10.1002/1529-0131(200009)43:9<2110::AID-ANR23>3.0.CO;2-U  0.48
2000 Richmond RS, Carlson CS, Register TC, Shanker G, Loeser RF. Functional estrogen receptors in adult articular cartilage: Estrogen replacement therapy increases chondrocyte synthesis of proteoglycans and insulin-like growth factor binding protein 2 Arthritis and Rheumatism. 43: 2081-2090. PMID 11014360 DOI: 10.1002/1529-0131(200009)43:9<2081::AID-ANR20>3.0.CO;2-I  0.48
2000 Messier SP, Loeser RF, Mitchell MN, Valle G, Morgan TP, Rejeski WJ, Ettinger WH. Exercise and weight loss in obese older adults with knee osteoarthritis: A preliminary study Journal of the American Geriatrics Society. 48: 1062-1072. PMID 10983905 DOI: 10.1111/j.1532-5415.2000.tb04781.x  0.48
1999 Fernihough JK, Richmond RS, Carlson CS, Cherpes T, Holly JMP, Loeser RF. Estrogen replacement therapy modulation of the insulin-like growth factor system in monkey knee joints Arthritis and Rheumatism. 42: 2103-2111. PMID 10524681 DOI: 10.1002/1529-0131(199910)42:10<2103::AID-ANR10>3.0.CO;2-S  0.48
1997 Loeser RF, Varnum BC, Carlson CS, Goldring MB, Liu ET, Sadiev S, Kute TE, Wallin R. Human chondrocyte expression of growth-arrest-specific gene 6 and the tyrosine kinase receptor axl: Potential role in autocrine signaling in cartilage Arthritis and Rheumatism. 40: 1455-1465. PMID 9259426 DOI: 10.1002/art.1780400814  0.48
1996 Carlson CS, Loeser RF, Purser CB, Gardin JF, Jerome CP. Osteoarthritis in cynomolgus macaques III: Effects of age, gender, and subchondral bone thickness on the severity of disease Journal of Bone and Mineral Research. 11: 1209-1217. PMID 8864894  0.48
1995 Carlson CS, Loeser RF, Johnstone B, Tulli HM, Dobson DB, Caterson B. Osteoarthritis in cynomolgus macaques. II. Detection of modulated proteoglycan epitopes in cartilage and synovial fluid. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 13: 399-409. PMID 7541454 DOI: 10.1002/jor.1100130314  0.48
1995 Loeser RF, Carlson CS, McGee MP. Expression of β1 Integrins by Cultured Articular Chondrocytes and in Osteoarthritic Cartilage Experimental Cell Research. 217: 248-257. PMID 7535235 DOI: 10.1006/excr.1995.1084  0.48
1994 Carlson CS, Loeser RF, Jayo MJ, Weaver DS, Adams MR, Jerome CP. Osteoarthritis in cynomolgus macaques: a primate model of naturally occurring disease. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 12: 331-9. PMID 8207586 DOI: 10.1002/jor.1100120305  0.48
1993 Carlson CS, Tulli HM, Jayo MJ, Loeser RF, Tracy RP, Mann KG, Adams MR. Immunolocalization of noncollagenous bone matrix proteins in lumbar vertebrae from intact and surgically menopausal cynomolgus monkeys Journal of Bone and Mineral Research. 8: 71-81. PMID 8427050  0.48
1992 Loeser R, Carlson CS, Tulli H, Jerome WG, Miller L, Wallin R. Articular-cartilage matrix γ-carboxyglutamic acid-containing protein. Characterization and immunolocalization Biochemical Journal. 282: 1-6. PMID 1540125  0.48
1990 Semble EL, Loeser RF, Wise CM. Therapeutic exercise for rheumatoid arthritis and osteoarthritis. Seminars in Arthritis and Rheumatism. 20: 32-40. PMID 2218551 DOI: 10.1016/0049-0172(90)90092-T  0.48
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