Thomas L. Rothstein - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Immunology, Cell Biology

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ray ME, Rothstein TL. Human VH4-34 antibodies derived from B1 cells are more frequently autoreactive than VH4-34 antibodies derived from memory cells. Frontiers in Immunology. 14: 1259827. PMID 38162664 DOI: 10.3389/fimmu.2023.1259827  0.452
2023 Gutknecht MF, Holodick NE, Rothstein TL. B cell extracellular vesicles contain monomeric IgM that binds antigen and enters target cells. Iscience. 26: 107526. PMID 37636058 DOI: 10.1016/j.isci.2023.107526  0.783
2022 Webster SE, Vos D, Rothstein TL, Holodick NE. Modulation of microbiome diversity and cytokine expression is influenced in a sex-dependent manner during aging. Frontiers in Microbiomes. 1. PMID 37426084 DOI: 10.3389/frmbi.2022.994464  0.685
2022 Rodriguez-Zhurbenko N, Quach TD, Rothstein TL, Hernandez AM. Human B-1 cells are important contributors to the naturally-occurring IgM pool against the tumor-associated ganglioside Neu5GcGM3. Frontiers in Immunology. 13: 1061651. PMID 36524112 DOI: 10.3389/fimmu.2022.1061651  0.344
2022 Srikakulapu P, Pattarabanjird T, Upadhye A, Bontha SV, Osinski V, Marshall MA, Garmey J, Deroissart J, Prohaska TA, Witztum JL, Binder CJ, Holodick NE, Rothstein TL, McNamara CA. B-1b Cells Have Unique Functional Traits Compared to B-1a Cells at Homeostasis and in Aged Hyperlipidemic Mice With Atherosclerosis. Frontiers in Immunology. 13: 909475. PMID 35935999 DOI: 10.3389/fimmu.2022.909475  0.823
2022 Husain-Krautter S, Lee J, Vos D, Gallego JA, Malhotra AK, Rothstein TL. Skewing of the Antibody Repertoire in Cerebrospinal Fluid B Cells from Healthy Controls and Patients with Schizophrenia. Behavioural Brain Research. 113743. PMID 35007628 DOI: 10.1016/j.bbr.2022.113743  0.494
2020 Khan N, Rothstein TL. The Alternate Pathway for BCR Signaling Induced by IL-4 Requires Lyn Tyrosine Kinase. Journal of Molecular Biology. PMID 33058880 DOI: 10.1016/j.jmb.2020.10.002  0.358
2020 Tsuji N, Rothstein TL, Holodick NE. Antigen Receptor Specificity and Cell Location Influence the Diversification and Selection of the B-1a Cell Pool with Age. Journal of Immunology (Baltimore, Md. : 1950). PMID 32561570 DOI: 10.4049/Jimmunol.1901302  0.79
2020 Kaku H, Rothstein TL. FAIM Is a Non-redundant Defender of Cellular Viability in the Face of Heat and Oxidative Stress and Interferes With Accumulation of Stress-Induced Protein Aggregates. Frontiers in Molecular Biosciences. 7: 32. PMID 32175331 DOI: 10.3389/Fmolb.2020.00032  0.304
2019 Guo B, Ludlow AV, Brightwell AS, Rothstein TL. Impairment of PD-L2 positive B1a cells enhances susceptibility to sepsis in RasGRP1-deficient mice. Cellular Immunology. 103993. PMID 31679751 DOI: 10.1016/J.Cellimm.2019.103993  0.383
2019 Upadhye A, Srikakulapu P, Gonen A, Hendrikx S, Perry HM, Nguyen AT, McSkimming C, Marshall M, Garmey J, Taylor A, Bender TP, Tsimikas S, Holodick NE, Rothstein TL, Witztum JL, et al. Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked To Human Coronary Atherosclerosis. Circulation Research. PMID 31549940 DOI: 10.1161/Circresaha.119.315786  0.811
2019 Ghosn E, Dorshkind K, Herzenberg LA, Holodick N, Kantor A, Montecino-Rodriguez E, Rothstein TL, Silverman GJ, Yang Y, Yoder MC, Yoshimoto M. B1 B cell progenitors. Science (New York, N.Y.). 364: 248. PMID 31000655 DOI: 10.1126/Science.Aax6784  0.825
2019 Rodriguez-Zhurbenko N, Quach TD, Hopkins TJ, Rothstein TL, Hernandez AM. Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age. Frontiers in Immunology. 10: 483. PMID 30941130 DOI: 10.3389/Fimmu.2019.00483  0.598
2018 Huang W, Quach TD, Dascalu C, Liu Z, Leung T, Byrne-Steele M, Pan W, Yang Q, Han J, Lesser M, Rothstein TL, Furie R, Mackay M, Aranow C, Davidson A. Belimumab promotes negative selection of activated autoreactive B cells in systemic lupus erythematosus patients. Jci Insight. 3. PMID 30185675 DOI: 10.1172/Jci.Insight.122525  0.604
2018 Aziz M, Ode Y, Zhou M, Ochani M, Holodick NE, Rothstein TL, Wang P. B-1a cells protect mice from sepsis-induced acute lung injury. Molecular Medicine (Cambridge, Mass.). 24: 26. PMID 30134811 DOI: 10.1186/S10020-018-0029-2  0.77
2018 Huang W, Quach T, Dascalu C, Liu Z, Leung T, Han J, Lesser M, Rothstein T, Furie R, Mackay M, Aranow C, Davidson A. AI-18 The effect of belimumab on B cell selection in human SLE Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Lsm.18  0.629
2017 Kaku H, Holodick NE, Tumang JR, Rothstein TL. CD25 (+) B-1a Cells Express Aicda. Frontiers in Immunology. 8: 672. PMID 28676801 DOI: 10.3389/Fimmu.2017.00672  0.832
2017 Aziz M, Holodick NE, Rothstein TL, Wang P. B-1a Cells Protect Mice from Sepsis: Critical Role of CREB. Journal of Immunology (Baltimore, Md. : 1950). PMID 28630091 DOI: 10.4049/Jimmunol.1602056  0.817
2016 Quách TD, Hopkins TJ, Holodick NE, Vuyyuru R, Manser T, Bayer RL, Rothstein TL. Human B-1 and B-2 B Cells Develop from Lin-CD34+CD38lo Stem Cells. Journal of Immunology (Baltimore, Md. : 1950). 197: 3950-3958. PMID 27815443 DOI: 10.4049/Jimmunol.1600630  0.822
2016 Olofsson PS, Steinberg BE, Sobbi R, Cox MA, Ahmed MN, Oswald M, Szekeres F, Hanes WM, Introini A, Liu SF, Holodick NE, Rothstein TL, Lövdahl C, Chavan SS, Yang H, et al. Blood pressure regulation by CD4(+) lymphocytes expressing choline acetyltransferase. Nature Biotechnology. PMID 27617738 DOI: 10.1038/Nbt.3663  0.746
2016 Guo B, Zhang L, Chiorazzi N, Rothstein TL. IL-4 rescues surface IgM expression in chronic lymphocytic leukemia. Blood. PMID 27226435 DOI: 10.1182/Blood-2015-11-682997  0.473
2016 Holodick NE, Vizconde T, Hopkins TJ, Rothstein TL. Age-Related Decline in Natural IgM Function: Diversification and Selection of the B-1a Cell Pool with Age. Journal of Immunology (Baltimore, Md. : 1950). 196: 4348-57. PMID 27183643 DOI: 10.4049/Jimmunol.1600073  0.793
2016 Rothstein TL. Natural Antibodies as Rheostats for Susceptibility to Chronic Diseases in the Aged. Frontiers in Immunology. 7: 127. PMID 27092140 DOI: 10.3389/Fimmu.2016.00127  0.378
2016 Holodick NE, Zeumer L, Rothstein TL, Morel L. Expansion of B-1a Cells with Germline Heavy Chain Sequence in Lupus Mice. Frontiers in Immunology. 7: 108. PMID 27047495 DOI: 10.3389/Fimmu.2016.00108  0.815
2016 Guo B, Rothstein TL. RasGRP1 Is an Essential Signaling Molecule for Development of B1a Cells with Autoantigen Receptors. Journal of Immunology (Baltimore, Md. : 1950). PMID 26851222 DOI: 10.4049/Jimmunol.1502132  0.551
2016 Sharma A, Kiripolsky J, Klimatcheva E, Howell A, Fereidouni F, Levenson R, Rothstein TL, Kramer JM. Early BAFF receptor blockade mitigates murine Sjögren's syndrome: Concomitant targeting of CXCL13 and the BAFF receptor prevents salivary hypofunction. Clinical Immunology (Orlando, Fla.). PMID 26826598 DOI: 10.1016/J.Clim.2016.01.015  0.357
2016 Quách TD, Rodríguez-Zhurbenko N, Hopkins TJ, Guo X, Hernández AM, Li W, Rothstein TL. Distinctions among Circulating Antibody-Secreting Cell Populations, Including B-1 Cells, in Human Adult Peripheral Blood. Journal of Immunology (Baltimore, Md. : 1950). PMID 26740107 DOI: 10.4049/Jimmunol.1501843  0.544
2015 Rothstein TL, Herzenberg LA, Holodick NE, Ghosn E. B-1 Cell Development and Function. Annals of the New York Academy of Sciences. 1362: v-vi. PMID 26662722 DOI: 10.1111/Nyas.12949  0.811
2015 Aziz M, Holodick NE, Rothstein TL, Wang P. The role of B-1 cells in inflammation. Immunologic Research. PMID 26427372 DOI: 10.1007/S12026-015-8708-3  0.811
2015 Kramer JM, Holodick NE, Vizconde TC, Raman I, Yan M, Li QZ, Gaile DP, Rothstein TL. Analysis of IgM antibody production and repertoire in a mouse model of Sjögren's syndrome. Journal of Leukocyte Biology. PMID 26382297 DOI: 10.1189/Jlb.2A0715-297R  0.767
2015 Engelbertsen D, Vallejo J, Quách TD, Fredrikson GN, Alm R, Hedblad B, Björkbacka H, Rothstein TL, Nilsson J, Bengtsson E. Low Levels of IgM Antibodies against an Advanced Glycation Endproduct-Modified Apolipoprotein B100 Peptide Predict Cardiovascular Events in Nondiabetic Subjects. Journal of Immunology (Baltimore, Md. : 1950). 195: 3020-5. PMID 26290603 DOI: 10.4049/Jimmunol.1402869  0.306
2015 Cui X, Zhang L, Magli AR, Catera R, Yan XJ, Griffin DO, Rothstein TL, Barrientos J, Kolitz JE, Allen SL, Rai KR, Chiorazzi N, Chu CC. Cytoplasmic myosin exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability. Leukemia. PMID 26220042 DOI: 10.1038/Leu.2015.204  0.521
2015 Holodick NE, Rothstein TL. B cells in the aging immune system: time to consider B-1 cells. Annals of the New York Academy of Sciences. 1362: 176-87. PMID 26194480 DOI: 10.1111/Nyas.12825  0.798
2015 Rothstein TL, Quach TD. The human counterpart of mouse B-1 cells. Annals of the New York Academy of Sciences. PMID 25988790 DOI: 10.1111/Nyas.12790  0.637
2014 Kaku H, Cheng KF, Al-Abed Y, Rothstein TL. A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production. Journal of Immunology (Baltimore, Md. : 1950). 193: 5904-13. PMID 25392527 DOI: 10.4049/Jimmunol.1400336  0.595
2014 Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. The Journal of Experimental Medicine. 211: 1243-56. PMID 24821911 DOI: 10.1084/Jem.20131471  0.495
2014 Holodick NE, Vizconde T, Rothstein TL. Splenic B-1a Cells Expressing CD138 Spontaneously Secrete Large Amounts of Immunoglobulin in Naïve Mice. Frontiers in Immunology. 5: 129. PMID 24734034 DOI: 10.3389/Fimmu.2014.00129  0.813
2014 Holodick NE, Vizconde T, Rothstein TL. B-1a cell diversity: nontemplated addition in B-1a cell Ig is determined by progenitor population and developmental location. Journal of Immunology (Baltimore, Md. : 1950). 192: 2432-41. PMID 24477911 DOI: 10.4049/Jimmunol.1300247  0.8
2014 Husain-krautter S, Gallego J, Malhotra A, Rothstein T. Proinflammatory cytokines, microRNAs and schizophrenia Journal of Neuroimmunology. 275: 62. DOI: 10.1016/J.Jneuroim.2014.08.164  0.401
2013 Holodick NE, Rothstein TL. Atypical Response of B-1 Cells to BCR Ligation: A Speculative Model. Frontiers in Immunology. 4: 457. PMID 24379817 DOI: 10.3389/Fimmu.2013.00457  0.814
2013 Li W, Batliwalla F, Rothstein TL. Human B-1 cells are not preplasmablasts: analysis of microarray data and other issues. Blood. 122: 3691-3. PMID 24263958 DOI: 10.1182/Blood-2013-08-520031  0.543
2013 Kramer JM, Klimatcheva E, Rothstein TL. CXCL13 is elevated in Sjögren's syndrome in mice and humans and is implicated in disease pathogenesis. Journal of Leukocyte Biology. 94: 1079-89. PMID 23904442 DOI: 10.1189/Jlb.0113036  0.36
2013 Guo B, Rothstein TL. IL-4 upregulates Igα and Igβ protein, resulting in augmented IgM maturation and B cell receptor-triggered B cell activation. Journal of Immunology (Baltimore, Md. : 1950). 191: 670-7. PMID 23776171 DOI: 10.4049/Jimmunol.1203211  0.52
2013 Rothstein TL, Griffin DO, Holodick NE, Quach TD, Kaku H. Human B-1 cells take the stage. Annals of the New York Academy of Sciences. 1285: 97-114. PMID 23692567 DOI: 10.1111/Nyas.12137  0.839
2013 Chen SS, Batliwalla F, Holodick NE, Yan XJ, Yancopoulos S, Croce CM, Rothstein TL, Chiorazzi N. Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: E1500-7. PMID 23550156 DOI: 10.1073/Pnas.1300616110  0.796
2013 Guo B, Rothstein TL. A novel Lyn-protein kinase Cδ/ε-protein kinase D axis is activated in B cells by signalosome-independent alternate pathway BCR signaling. European Journal of Immunology. 43: 1643-50. PMID 23457006 DOI: 10.1002/Eji.201242830  0.394
2012 Wang Y, Rothstein TL. Induction of Th17 cell differentiation by B-1 cells. Frontiers in Immunology. 3: 281. PMID 22973276 DOI: 10.3389/Fimmu.2012.00281  0.625
2012 Griffin DO, Rothstein TL. Human b1 cell frequency: isolation and analysis of human b1 cells. Frontiers in Immunology. 3: 122. PMID 22654880 DOI: 10.3389/Fimmu.2012.00122  0.567
2012 Griffin DO, Rothstein TL. Human "orchestrator" CD11b(+) B1 cells spontaneously secrete interleukin-10 and regulate T-cell activity. Molecular Medicine (Cambridge, Mass.). 18: 1003-8. PMID 22634719 DOI: 10.2119/Molmed.2012.00203  0.648
2012 Griffin DO, Quach T, Batliwalla F, Andreopoulos D, Holodick NE, Rothstein TL. Human CD11b+ B1 cells are not monocytes: A reply to "Gene profiling of CD11b+ and CD11b- B1 cell subsets reveals potential cell sorting artifacts". The Journal of Experimental Medicine. 209: 434-6. PMID 22412176 DOI: 10.1084/Jem.20120403  0.826
2011 Tumang JR, Holodick NE, Vizconde TC, Kaku H, Francés R, Rothstein TL. A CD25⁻ positive population of activated B1 cells expresses LIFR and responds to LIF. Frontiers in Immunology. 2: 6. PMID 22566797 DOI: 10.3389/Fimmu.2011.00006  0.813
2011 Rothstein TL. Grand challenges in B cell biology. Frontiers in Immunology. 2: 2. PMID 22566793 DOI: 10.3389/Fimmu.2011.00002  0.627
2011 Griffin DO, Holodick NE, Rothstein TL. Human B1 cells are CD3-: A reply to "A human equivalent of mouse B-1 cells?" and "The nature of circulating CD27+CD43+ B cells". The Journal of Experimental Medicine. 208: 2566-9. PMID 22184682 DOI: 10.1084/Jem.20111761  0.817
2011 Griffin DO, Rothstein TL. A small CD11b(+) human B1 cell subpopulation stimulates T cells and is expanded in lupus. The Journal of Experimental Medicine. 208: 2591-8. PMID 22110167 DOI: 10.1084/Jem.20110978  0.665
2011 Griffin DO, Holodick NE, Rothstein TL. Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-. The Journal of Experimental Medicine. 208: 67-80. PMID 21220451 DOI: 10.1084/Jem.20101499  0.802
2011 Zhong X, Rothstein TL. L2pB1: a new player in autoimmunity. Molecular Immunology. 48: 1292-300. PMID 21195478 DOI: 10.1016/J.Molimm.2010.12.006  0.781
2010 Holodick NE, Tumang JR, Rothstein TL. Immunoglobulin secretion by B1 cells: differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells. European Journal of Immunology. 40: 3007-16. PMID 21061433 DOI: 10.1002/Eji.201040545  0.84
2010 Kaku H, Rothstein TL. Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B-1 cells through lineage-specific activity of a unique, intronic promoter. Genes and Immunity. 11: 55-66. PMID 19710692 DOI: 10.1038/Gene.2009.68  0.514
2010 Kaku H, Rothstein TL. Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment (Journal of Immunology (2009) 183, (1667-1674)) Journal of Immunology. 185: 771. DOI: 10.4049/jimmunol.1090047  0.456
2010 Chen S, Batliwalla F, Holodick N, Yan X, Rothstein TL, Chiorazzi N. Murine TCL1 CLL Cells with B-Cell Receptors Specific for the Autoantigen Phosphatidylcholine Have a Selective Advantage During Adoptive Transfer Blood. 116: 373-373. DOI: 10.1182/Blood.V116.21.373.373  0.808
2009 Zhong X, Lau S, Bai C, Degauque N, Holodick NE, Steven SJ, Tumang J, Gao W, Rothstein TL. A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice. Arthritis and Rheumatism. 60: 3734-43. PMID 19950285 DOI: 10.1002/Art.25015  0.853
2009 Kaku H, Rothstein TL. Fas apoptosis inhibitory molecule expression in B cells is regulated through IRF4 in a feed-forward mechanism. Journal of Immunology (Baltimore, Md. : 1950). 183: 5575-81. PMID 19843941 DOI: 10.4049/Jimmunol.0901988  0.528
2009 Holodick NE, Repetny K, Zhong X, Rothstein TL. Adult BM generates CD5+ B1 cells containing abundant N-region additions. European Journal of Immunology. 39: 2383-94. PMID 19714574 DOI: 10.1002/Eji.200838920  0.864
2009 Kaku H, Rothstein TL. Fas apoptosis inhibitory molecule enhances CD40 signaling in B cells and augments the plasma cell compartment. Journal of Immunology (Baltimore, Md. : 1950). 183: 1667-74. PMID 19592656 DOI: 10.4049/Jimmunol.0900056  0.564
2009 Holodick NE, Tumang JR, Rothstein TL. Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells. Molecular Immunology. 46: 3029-36. PMID 19592097 DOI: 10.1016/J.Molimm.2009.06.011  0.83
2009 Rothstein TL, Guo B. Receptor crosstalk: reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin. Journal of Internal Medicine. 265: 632-43. PMID 19493057 DOI: 10.1111/J.1365-2796.2009.02103.X  0.523
2009 Repetny KJ, Zhong X, Holodick NE, Rothstein TL, Hansen U. Binding of LBP-1a to specific immunoglobulin switch regions in vivo correlates with specific repression of class switch recombination. European Journal of Immunology. 39: 1387-94. PMID 19384868 DOI: 10.1002/Eji.200838226  0.807
2009 Guo B, Tumang JR, Rothstein TL. B cell receptor crosstalk: B cells express osteopontin through the combined action of the alternate and classical BCR signaling pathways. Molecular Immunology. 46: 587-91. PMID 18952291 DOI: 10.1016/J.Molimm.2008.07.029  0.56
2007 Busconi L, Bauer JW, Tumang JR, Laws A, Perkins-Mesires K, Tabor AS, Lau C, Corley RB, Rothstein TL, Lund FE, Behrens TW, Marshak-Rothstein A. Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9. Journal of Immunology (Baltimore, Md. : 1950). 179: 7397-405. PMID 18025183 DOI: 10.4049/Jimmunol.179.11.7397  0.537
2007 Zhong X, Tumang JR, Gao W, Bai C, Rothstein TL. PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for V(H)11/V(H)12 and phosphatidylcholine binding. European Journal of Immunology. 37: 2405-10. PMID 17683117 DOI: 10.1002/Eji.200737461  0.72
2007 Zhong X, Gao W, Degauque N, Bai C, Lu Y, Kenny J, Oukka M, Strom TB, Rothstein TL. Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells. European Journal of Immunology. 37: 2400-4. PMID 17683116 DOI: 10.1002/Eji.200737296  0.776
2007 Dye JR, Palvanov A, Guo B, Rothstein TL. B cell receptor cross-talk: exposure to lipopolysaccharide induces an alternate pathway for B cell receptor-induced ERK phosphorylation and NF-kappa B activation. Journal of Immunology (Baltimore, Md. : 1950). 179: 229-35. PMID 17579042 DOI: 10.4049/Jimmunol.179.1.229  0.454
2007 Mineva ND, Rothstein TL, Meyers JA, Lerner A, Sonenshein GE. CD40 ligand-mediated activation of the de novo RelB NF-kappaB synthesis pathway in transformed B cells promotes rescue from apoptosis. The Journal of Biological Chemistry. 282: 17475-85. PMID 17446175 DOI: 10.1074/Jbc.M607313200  0.569
2007 Guo B, Blair D, Chiles TC, Lowell CA, Rothstein TL. Cutting Edge: B cell receptor (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn. Journal of Immunology (Baltimore, Md. : 1950). 178: 4726-30. PMID 17404251 DOI: 10.4049/Jimmunol.178.8.4726  0.444
2007 Francés R, Tumang JR, Rothstein TL. Extreme skewing of annexin II and S100A6 expression identified by proteomic analysis of peritoneal B-1 cells. International Immunology. 19: 59-65. PMID 17135445 DOI: 10.1093/Intimm/Dxl122  0.584
2006 Mataraza JM, Tumang JR, Gumina MR, Gurdak SM, Rothstein TL, Chiles TC. Disruption of cyclin D3 blocks proliferation of normal B-1a cells, but loss of cyclin D3 is compensated by cyclin D2 in cyclin D3-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 787-95. PMID 16818732 DOI: 10.4049/Jimmunol.177.2.787  0.49
2006 Hastings WD, Tumang JR, Behrens TW, Rothstein TL. Peritoneal B-2 cells comprise a distinct B-2 cell population with B-1b-like characteristics. European Journal of Immunology. 36: 1114-23. PMID 16609926 DOI: 10.1002/Eji.200535142  0.868
2006 Francés R, Tumang JR, Kaku H, Gurdak SM, Rothstein TL. B-1 cells express transgelin 2: unexpected lymphocyte expression of a smooth muscle protein identified by proteomic analysis of peritoneal B-1 cells. Molecular Immunology. 43: 2124-9. PMID 16487589 DOI: 10.1016/J.Molimm.2005.12.011  0.646
2006 Hastings WD, Gurdak SM, Tumang JR, Rothstein TL. CD5+/Mac-1- peritoneal B cells: a novel B cell subset that exhibits characteristics of B-1 cells. Immunology Letters. 105: 90-6. PMID 16481048 DOI: 10.1016/J.Imlet.2006.01.002  0.866
2006 Rosenbauer F, Owens BM, Yu L, Tumang JR, Steidl U, Kutok JL, Clayton LK, Wagner K, Scheller M, Iwasaki H, Liu C, Hackanson B, Akashi K, Leutz A, Rothstein TL, et al. Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1. Nature Genetics. 38: 27-37. PMID 16311598 DOI: 10.1038/Ng1679  0.488
2006 Yeo SG, Tumang JR, Rothstein TL. Characteristic features of B cells in murine cervical lymph nodes. Acta Oto-Laryngologica. 126: 56-61. PMID 16308256 DOI: 10.1080/00016480510012345  0.501
2005 Barrington RA, Zhang M, Zhong X, Jonsson H, Holodick N, Cherukuri A, Pierce SK, Rothstein TL, Carroll MC. CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses. Journal of Immunology (Baltimore, Md. : 1950). 175: 2859-67. PMID 16116172 DOI: 10.4049/Jimmunol.175.5.2859  0.845
2005 Francés R, Tumang JR, Rothstein TL. B-1 cells are deficient in Lck: defective B cell receptor signal transduction in B-1 cells occurs in the absence of elevated Lck expression. Journal of Immunology (Baltimore, Md. : 1950). 175: 27-31. PMID 15972627 DOI: 10.4049/Jimmunol.175.1.27  0.658
2005 Mizuno T, Rothstein TL. B cell receptor (BCR) cross-talk: CD40 engagement creates an alternate pathway for BCR signaling that activates I kappa B kinase/I kappa B alpha/NF-kappa B without the need for PI3K and phospholipase C gamma. Journal of Immunology (Baltimore, Md. : 1950). 174: 6062-70. PMID 15879100 DOI: 10.4049/Jimmunol.174.10.6062  0.498
2005 Guo B, Rothstein TL. B cell receptor (BCR) cross-talk: IL-4 creates an alternate pathway for BCR-induced ERK activation that is phosphatidylinositol 3-kinase independent. Journal of Immunology (Baltimore, Md. : 1950). 174: 5375-81. PMID 15843535 DOI: 10.4049/Jimmunol.174.9.5375  0.424
2005 Mizuno T, Rothstein TL. B cell receptor (BCR) cross-talk: CD40 engagement enhances BCR-induced ERK activation. Journal of Immunology (Baltimore, Md. : 1950). 174: 3369-76. PMID 15749869 DOI: 10.4049/Jimmunol.174.6.3369  0.454
2005 Tumang JR, Francés R, Yeo SG, Rothstein TL. Spontaneously Ig-secreting B-1 cells violate the accepted paradigm for expression of differentiation-associated transcription factors. Journal of Immunology (Baltimore, Md. : 1950). 174: 3173-7. PMID 15749846 DOI: 10.4049/Jimmunol.174.6.3173  0.626
2005 Mataraza JM, Tumang JR, Rothstein TL, Chiles TC. Cyclin D3 Is Required for Peritoneal B-1a Lymphocyte Proliferation. Blood. 106: 1353-1353. DOI: 10.1182/Blood.V106.11.1353.1353  0.589
2004 Foote LC, Evans JW, Cifuni JM, Siracusa MC, Monteforte GM, McCole JL, D'Orazio CC, Hastings WD, Rothstein TL. Interleukin-4 produces a breakdown of tolerance in vivo with autoantibody formation and tissue damage. Autoimmunity. 37: 569-77. PMID 15763919 DOI: 10.1080/08916930400020602  0.797
2004 Tumang JR, Hastings WD, Bai C, Rothstein TL. Peritoneal and splenic B-1 cells are separable by phenotypic, functional, and transcriptomic characteristics. European Journal of Immunology. 34: 2158-67. PMID 15259013 DOI: 10.1002/Eji.200424819  0.864
2004 Zhong X, Bai C, Gao W, Strom TB, Rothstein TL. Suppression of expression and function of negative immune regulator PD-1 by certain pattern recognition and cytokine receptor signals associated with immune system danger. International Immunology. 16: 1181-8. PMID 15237109 DOI: 10.1093/Intimm/Dxh121  0.667
2004 Piatelli MJ, Wardle C, Blois J, Doughty C, Schram BR, Rothstein TL, Chiles TC. Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kappa B signaling pathways are required for B cell antigen receptor-mediated cyclin D2 induction in mature B cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 2753-62. PMID 14978074 DOI: 10.4049/Jimmunol.172.5.2753  0.797
2004 Greenwald RJ, Tumang JR, Sinha A, Currier N, Cardiff RD, Rothstein TL, Faller DV, Denis GV. E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia. Blood. 103: 1475-84. PMID 14563639 DOI: 10.1182/Blood-2003-06-2116  0.585
2004 Yeo SG, Cho JS, Park DC, Rothstein TL. B-1 Cells Differ from Conventional B (B-2) Cells: Difference in Proliferation Immune Network. 4: 155. DOI: 10.4110/IN.2004.4.3.155  0.57
2004 Tumang JR, Frances R, Rothstein TL. A Unique Transcriptional Profile for Spontaneously Immunoglobulin Secreting B-1 Cells. Blood. 104: 3236-3236. DOI: 10.1182/Blood.V104.11.3236.3236  0.622
2004 Zhong X, Bai C, Rothstein TL. Suppression of Negative Immune Regulators PD-1 and PD-L1 Expression on Lymphocytes by Inflammatory Cytokines. Blood. 104: 2663-2663. DOI: 10.1182/Blood.V104.11.2663.2663  0.625
2003 Mizuno T, Zhong X, Rothstein TL. Fas-induced apoptosis in B cells. Apoptosis : An International Journal On Programmed Cell Death. 8: 451-60. PMID 12975576 DOI: 10.1023/A:1025534223168  0.769
2003 Piatelli M, Tanguay D, Rothstein T, Chiles T. Cell cycle control mechanisms in B-1 and B-2 lymphoid subsets. Immunologic Research. 27: 31-52. PMID 12637767 DOI: 10.1385/Ir:27:1:31  0.637
2003 Schram BR, Rothstein TL. NF-kappa B is required for surface Ig-induced Fas resistance in B cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 3118-24. PMID 12626568 DOI: 10.4049/Jimmunol.170.6.3118  0.847
2003 Mizuno T, Rothstein TL. Cutting edge: CD40 engagement eliminates the need for Bruton's tyrosine kinase in B cell receptor signaling for NF-kappa B. Journal of Immunology (Baltimore, Md. : 1950). 170: 2806-10. PMID 12626529 DOI: 10.4049/Jimmunol.170.6.2806  0.628
2002 Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ. Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. The Journal of Biological Chemistry. 277: 27169-75. PMID 12023955 DOI: 10.1074/Jbc.M201207200  0.514
2002 Rothstein TL. Cutting edge commentary: two B-1 or not to be one. Journal of Immunology (Baltimore, Md. : 1950). 168: 4257-61. PMID 11970963 DOI: 10.4049/Jimmunol.168.9.4257  0.658
2002 Irigoyen M, Mizuno T, Zhong X, Negm RS, Schneider TJ, Rothstein TL. B cell activation leads to upregulated expression of the murine Sik-similar protein gene Molecular Immunology. 38: 861-866. PMID 11922944 DOI: 10.1016/S0161-5890(01)00120-1  0.777
2002 Tumang JR, Negm RS, Solt LA, Schneider TJ, Colarusso TP, Hastings WD, Woodland RT, Rothstein TL. BCR engagement induces Fas resistance in primary B cells in the absence of functional Bruton's tyrosine kinase Journal of Immunology. 168: 2712-2719. PMID 11884437 DOI: 10.4049/Jimmunol.168.6.2712  0.823
2001 Fischer GM, Solt LA, Hastings WD, Yang K, Gerstein RM, Nikolajczyk BS, Clarke SH, Rothstein TL. Splenic and peritoneal B-1 cells differ in terms of transcriptional and proliferative features that separate peritoneal B-1 from splenic B-2 cells. Cellular Immunology. 213: 62-71. PMID 11747357 DOI: 10.1006/Cimm.2001.1860  0.872
2001 Owyang AM, Tumang JR, Schram BR, Hsia CY, Behrens TW, Rothstein TL, Liou HC. c-Rel is required for the protection of B cells from antigen receptor-mediated, but not Fas-mediated, apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 167: 4948-56. PMID 11673501 DOI: 10.4049/Jimmunol.167.9.4948  0.8
2001 Zhong X, Schneider TJ, Cabral DS, Donohoe TJ, Rothstein TL. An alternatively spliced long form of Fas apoptosis inhibitory molecule (FAIM) with tissue-specific expression in the brain. Molecular Immunology. 38: 65-72. PMID 11483211 DOI: 10.1016/S0161-5890(01)00035-9  0.634
2001 Tanguay DA, Colarusso TP, Doughty C, Pavlovic-Ewers S, Rothstein TL, Chiles TC. Cutting edge: differential signaling requirements for activation of assembled cyclin D3-cdk4 complexes in B-1 and B-2 lymphocyte subsets. Journal of Immunology (Baltimore, Md. : 1950). 166: 4273-7. PMID 11254678 DOI: 10.4049/Jimmunol.166.7.4273  0.554
2001 Fan H, Rothstein TL. Lymphokine dependence of STAT3 activation produced by surface immunoglobulin cross-linking and by phorbol ester plus calcium ionophore treatment in B cells. European Journal of Immunology. 31: 665-71. PMID 11180132 DOI: 10.1002/1521-4141(200102)31:2<665::Aid-Immu665>3.0.Co;2-1  0.527
2000 Rothstein TL. Inducible resistance to Fas-mediated apoptosis in B cells Cell Research. 10: 245-266. PMID 11191348 DOI: 10.1038/Sj.Cr.7290053  0.562
2000 Rothstein TL, Fischer GM, Tanguay DA, Pavlovic S, Colarusso TP, Gerstein RM, Clarke SH, Chiles TC. STAT3 activation, chemokine receptor expression, and cyclin-Cdk function in B-1 cells. Current Topics in Microbiology and Immunology. 252: 121-30. PMID 11125469 DOI: 10.1007/978-3-642-57284-5_13  0.765
2000 Rothstein TL, Zhong X, Schram BR, Negm RS, Donohoe TJ, Cabral DS, Foote LC, Schneider TJ. Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule. Immunological Reviews. 176: 116-33. PMID 11043772 DOI: 10.1034/J.1600-065X.2000.00616.X  0.836
2000 Karras JG, McKay RA, Lu T, Pych J, Frank DA, Rothstein TL, Monia BP. STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression. Cellular Immunology. 202: 124-35. PMID 10896772 DOI: 10.1006/Cimm.2000.1661  0.617
1999 Tanguay DA, Colarusso TP, Pavlovic S, Irigoyen M, Howard RG, Bartek J, Chiles TC, Rothstein TL. Early induction of cyclin D2 expression in phorbol ester-responsive B-1 lymphocytes. The Journal of Experimental Medicine. 189: 1685-90. PMID 10359571 DOI: 10.1084/Jem.189.11.1685  0.571
1999 Schneider TJ, Fischer GM, Donohoe TJ, Colarusso TP, Rothstein TL. A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes. The Journal of Experimental Medicine. 189: 949-56. PMID 10075978 DOI: 10.1084/Jem.189.6.949  0.771
1998 Francis DA, Sen R, Rice N, Rothstein TL. Receptor-specific induction of NF-κB components in primary B cells International Immunology. 10: 285-293. PMID 9576616 DOI: 10.1093/Intimm/10.3.285  0.475
1998 Foote LC, Marshak-Rothstein A, Rothstein TL. Tolerant B lymphocytes acquire resistance to Fas-mediated apoptosis after treatment with interleukin 4 but not after treatment with specific antigen unless a surface immunoglobulin threshold is exceeded Journal of Experimental Medicine. 187: 847-853. PMID 9500787 DOI: 10.1084/Jem.187.6.847  0.626
1997 Wang Z, Karras JG, Colarusso TP, Foote LC, Rothstein TL. Unmethylated CpG motifs protect murine B lymphocytes against Fas-mediated apoptosis. Cellular Immunology. 180: 162-7. PMID 9341746 DOI: 10.1006/Cimm.1997.1156  0.607
1997 Francis DA, Sen R, Rothstein TL. Receptor-specific regulation of NF-κB, c-Myc and Fas-mediated apoptosis in primary B cells Current Topics in Microbiology and Immunology. 224: 83-90. PMID 9308231 DOI: 10.1007/978-3-642-60801-8_8  0.314
1997 Fine A, Anderson NL, Rothstein TL, Williams MC, Gochuico BR. Fas expression in pulmonary alveolar type II cells. The American Journal of Physiology. 273: L64-71. PMID 9252541 DOI: 10.1152/Ajplung.1997.273.1.L64  0.404
1997 Jacobson BA, Foote LC, Panka DJ, Ju ST, Rothstein TL, Marshak-Rothstein A. Unique site of autoantibody production in Fas-deficient mice Annals of the New York Academy of Sciences. 815: 218-229. PMID 9186658 DOI: 10.1111/J.1749-6632.1997.Tb52063.X  0.593
1997 Foote LC, Marshak-Rothstein A, Rothstein TL. Inducible Fas-resistance mediated by IL-4 in activated B cells Annals of the New York Academy of Sciences. 815: 114-115. PMID 9186645 DOI: 10.1111/J.1749-6632.1997.Tb52050.X  0.477
1997 Jacobson BA, Rothstein TL, Marshak-Rothstein A. Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice Immunological Reviews. 156: 103-110. PMID 9176703 DOI: 10.1111/J.1600-065X.1997.Tb00962.X  0.44
1997 Karras JG, Wang Z, Huo L, Howard RG, Frank DA, Rothstein TL. Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes. The Journal of Experimental Medicine. 185: 1035-42. PMID 9091577 DOI: 10.1084/Jem.185.6.1035  0.622
1997 Rothstein TL. Signals and susceptibility to programmed death in b cells. Current Opinion in Immunology. 8: 362-71. PMID 8793998 DOI: 10.1016/S0952-7915(96)80126-9  0.472
1996 Rothstein TL, Foote LC, Schneider TJ, Fischer GM, Jacobson BA, Lynch DH, Ju ST, Marshak-Rothstein A. Inducible resistance to Fas-mediated apoptosis in primary B lymphocytes Advances in Experimental Medicine and Biology. 406: 177-189. PMID 8910684 DOI: 10.1007/978-1-4899-0274-0_19  0.756
1996 Foote LC, Schneider TJ, Fischer GM, Wang JKM, Rasmussen B, Campbell KA, Lynch DH, Ju ST, Marshak-Rothstein A, Rothstein TL. Intracellular Signaling for Inducible Antigen Receptor-Mediated Fas Resistance in B Cells Journal of Immunology. 157: 1878-1885. PMID 8757305  0.727
1996 Ahearn JM, Fischer MB, Croix D, Goerg S, Ma M, Xia J, Zhou X, Howard RG, Rothstein TL, Carroll MC. Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen. Immunity. 4: 251-62. PMID 8624815 DOI: 10.1016/S1074-7613(00)80433-1  0.592
1996 Xie H, Wang Z, Rothstein TL. Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes. Cellular Immunology. 169: 264-70. PMID 8620554 DOI: 10.1006/Cimm.1996.0117  0.432
1996 Ozdemirli M, El-Khatib M, Foote LC, Wang JKM, Marshak-Rothstein A, Rothstein TL, Ju ST. Fas (CD95)/Fas ligand interactions regulate antigen-specific, major histocompatibility complex-restricted T/B cell proliferative responses European Journal of Immunology. 26: 415-419. PMID 8617312 DOI: 10.1002/Eji.1830260222  0.59
1996 Wu M, Lee H, Bellas RE, Schauer SL, Arsura M, Katz D, FitzGerald MJ, Rothstein TL, Sherr DH, Sonenshein GE. Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells. The Embo Journal. 15: 4682-4690. DOI: 10.1002/J.1460-2075.1996.Tb00845.X  0.5
1995 Wang Z, Morris DL, Rothstein TL. Constitutive and inducible levels of egr-1 and c-myc early growth response gene expression in self-renewing B-1 lymphocytes Cellular Immunology. 162: 309-314. PMID 7743559 DOI: 10.1006/Cimm.1995.1083  0.629
1995 Francis DA, Karras JG, Ke Xy, Sen R, Rothstein TL. Induction of the transcription factors NF-κB, AP-1 and NF-AT during B cell stimulation through the CD40 receptor International Immunology. 7: 151-161. PMID 7537532 DOI: 10.1093/Intimm/7.2.151  0.534
1995 Rothstein TL, Wang JKM, Panka DJ, Foote LC, Wang Z, Stanger B, Cui H, Ju ST, Marshak-Rothstein A. Protection against Fas-dependent Thl-mediated apoptosis by antigen receptor engagement in B cells Nature. 374: 163-165. PMID 7533263 DOI: 10.1038/374163A0  0.66
1995 Dziennis S, Van Etten R, Pahl H, Morris D, Rothstein T, Blosch C, Perlmutter R, Tenen D. The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice [published erratum appears in Blood 1995 Apr 1;85(7):1983] Blood. 85: 319-329. DOI: 10.1182/Blood.V85.2.319.Bloodjournal852319  0.344
1995 Morris DL, Rothstein TL. Analysis of B-1 cell activation Methods: a Companion to Methods in Enzymology. 8: 11-25. DOI: 10.1006/Meth.1995.1040  0.639
1994 Huo L, Chung WH, Rothstein TL. C-terminal sequence of the NF-κB p50 precursor from primary murine B-lymphocytes Gene. 139: 287-288. PMID 8112620 DOI: 10.1016/0378-1119(94)90771-4  0.468
1994 Tanguay DA, Dickinson JA, McManus BJ, Huo L, Rothstein TL, Chiles TC. Activation of AP-1 in primary B lymphocytes by surface immunoglobulin requires de novo Jun-B synthesis Cellular Immunology. 158: 281-291. PMID 7923384 DOI: 10.1006/Cimm.1994.1276  0.58
1994 Venkataraman L, Francis DA, Wang Z, Liu J, Rothstein TL, Sen R. Cyclosporin-a sensitive induction of NF-AT in murine B cells Immunity. 1: 189-196. PMID 7889407 DOI: 10.1016/1074-7613(94)90097-3  0.612
1994 Morris DL, Rothstein TL. Decreased surface IgM receptor-mediated activation of phospholipase Cγ2 in B-1 lymphocytes International Immunology. 6: 1011-1016. PMID 7524640 DOI: 10.1093/Intimm/6.7.1011  0.575
1993 Liu J, Sen R, Rothstein TL. Abnormal κB-binding protein in the cytoplasm of a plasmacytoma cell line that lacks nuclear expression of NF-κB Molecular Immunology. 30: 479-489. PMID 8464429 DOI: 10.1016/0161-5890(93)90116-S  0.561
1993 Lalmanach-Girard AC, Chiles TC, Parker DC, Rothstein TL. T cell-dependent induction of NF-κB in B cells Journal of Experimental Medicine. 177: 1215-1219. PMID 8459216 DOI: 10.1084/Jem.177.4.1215  0.658
1993 Morris DL, Rothstein TL. Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes Journal of Experimental Medicine. 177: 857-861. PMID 8436914 DOI: 10.1084/Jem.177.3.857  0.622
1992 Rothstein TL, Kolber DL, Cohen DP. CD5-like phorbol-ester responsiveness in conventional B cells activated through surface immunoglobulin. Annals of the New York Academy of Sciences. 651: 176-8. PMID 1376037 DOI: 10.1111/J.1749-6632.1992.Tb24613.X  0.533
1991 Kolber DL, Shultz LD, Rothstein TL. Phorbol ester responsiveness of murine Ly-1-lineage B cells from normal and viable motheaten mutant mice. European Journal of Immunology. 21: 721-729. PMID 2009913 DOI: 10.1002/Eji.1830210327  0.596
1991 Tilzey JF, Chiles TC, Rothstein TL. Jun-B gene expression mediated by the surface immunoglobulin receptor of primary B lymphocytes. Biochemical and Biophysical Research Communications. 175: 77-83. PMID 1900155 DOI: 10.1016/S0006-291X(05)81202-1  0.574
1990 Murphy TP, Kolber DL, Rothstein TL. Elevated expression of Pgp-1 (Ly-24) by murine peritoneal B lymphocytes. European Journal of Immunology. 20: 1137-42. PMID 2192903 DOI: 10.1002/Eji.1830200529  0.632
1990 Miller PD, Pothoulakis C, Baeker TR, LaMont JT, Rothstein TL. Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore. Cellular Immunology. 126: 155-63. PMID 2105851 DOI: 10.1016/0008-8749(90)90308-E  0.401
1990 Rothstein TL. Polyreactive low-affinity IgM antibodies produced by CD5+ B cells. Immunology Today. 11: 152. PMID 1692464 DOI: 10.1016/0167-5699(90)90062-E  0.535
1989 van Haelst-Pisani C, Cragoe EJ, Rothstein TL. Cytoplasmic alkalinization produced by the combination of anti-immunoglobulin antibody plus cytochalasin D in murine B lymphocytes. Experimental Cell Research. 183: 251-6. PMID 2786816 DOI: 10.1016/0014-4827(89)90435-7  0.443
1989 Rothstein TL. Interleukin-4 enhances peritoneal B cell stimulation induced by phorbol ester. Cellular Immunology. 120: 450-9. PMID 2785861 DOI: 10.1016/0008-8749(89)90212-8  0.56
1989 Wolfowicz CB, Lyons S, Mahon CA, Marshak-Rothstein A, Rothstein TL. Isolation of self-recognizing IgG2a monoclonal rheumatoid factors Clinical Immunology and Immunopathology. 52: 313-322. PMID 2736811 DOI: 10.1016/0090-1229(89)90182-7  0.382
1989 Cohen DP, Rothstein TL. Adenosine 3',5'-cyclic monophosphate modulates the mitogenic responses of murine B lymphocytes. Cellular Immunology. 121: 113-24. PMID 2470515 DOI: 10.1016/0008-8749(89)90009-9  0.444
1988 Buckler AJ, Rothstein TL, Sonenshein GE. Two-step stimulation of B lymphocytes to enter DNA synthesis: Synergy between anti-immunoglobulin antibody and cytochalasin on expression of c-myc and a G1-specific gene Molecular and Cellular Biology. 8: 1371-1375. PMID 3285181 DOI: 10.1128/Mcb.8.3.1371  0.418
1988 Buckler AJ, Kessler DJ, Duyao MP, Rothstein TL, Sonenshein GE. Regulation of c-myc gene transcription in B lymphocytes: mechanisms of negative and positive control Current Topics in Microbiology and Immunology. 141: 238-246. PMID 3265090 DOI: 10.1007/978-3-642-74006-0_32  0.438
1987 Shlomchik MJ, Marshak-Rothstein A, Wolfowicz CB, Rothstein TL, Weigert MG. The role of clonal selection and somatic mutation in autoimmunity. Nature. 328: 805-11. PMID 3498121 DOI: 10.1038/328805A0  0.34
1987 Rothstein TL, Baeker TR, Miller RA, Kolber DL. Stimulation of murine B cells by the combination of calcium ionophore plus phorbol ester. Cellular Immunology. 102: 364-73. PMID 3492280 DOI: 10.1016/0008-8749(86)90430-2  0.494
1987 Rothstein TL, Kolber DL, Simons ER, Baeker TR. Inhibition by phorbol esters of antiimmunoglobulin-induced calcium signalling and B-cell activation. Journal of Cellular Physiology. 129: 347-55. PMID 3491085 DOI: 10.1002/Jcp.1041290313  0.383
1987 ROTHSTEIN TL, KOLBER DL. Two Dual-Signal Pathways for Stimulation of B Cells Mediated by Calcium Ionophores Annals of the New York Academy of Sciences. 494: 160-161. DOI: 10.1111/J.1749-6632.1987.Tb29510.X  0.454
1986 Baeker TR, Rothstein TL. Effects of anti-IgM on mitogen-induced proliferation of human B-lymphocyte malignancies. Clinical Immunology and Immunopathology. 39: 285-97. PMID 3084144 DOI: 10.1016/0090-1229(86)90092-9  0.487
1984 Rothstein TL, Miller RA, Parker DJ, Kelly E, Vastola AP, Marshak-Rothstein A. Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice. The Journal of Experimental Medicine. 159: 1283-8. PMID 6608575 DOI: 10.1084/Jem.159.4.1283  0.507
1983 Rothstein TL, Margolies MN, Gefter ML, Marshak Rothstein A. Fine-specificity of idiotope suppression in the A/J anti-azophenylarsonate response Journal of Experimental Medicine. 157: 795-800. PMID 6185619 DOI: 10.1084/Jem.157.2.795  0.302
1977 Mage MG, McHugh LL, Rothstein TL. Mouse lymphocytes with and without surface immunoglobulin: preparative scale separation in polystyrene tissue culture dishes coated with specifically purified anti-immunoglobulin. Journal of Immunological Methods. 15: 47-56. PMID 15036 DOI: 10.1016/0022-1759(77)90016-3  0.388
1974 Rothstein TL, Blum JJ. Lysosomal physiology in Tetrahymena. II. Effect of culture age and temperature on the extracellular release of 3 acid hydrolases. The Journal of Protozoology. 21: 163-8. PMID 4817979 DOI: 10.1111/J.1550-7408.1974.Tb03632.X  0.306
Show low-probability matches.