Paul J. Chiao - Publications

Affiliations: 
The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Molecular Biology, Oncology, Cell Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ji S, Qin Y, Liang C, Huang R, Shi S, Liu J, Jin K, Liang D, Xu W, Zhang B, Liu L, Liu C, Xu J, Ni Q, Chiao PJ, et al. FBW7 (F-box and WD repeat domain-containing 7) negatively regulates glucose metabolism by targeting the c-Myc/TXNIP (thioredoxin binding protein) axis in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26983463 DOI: 10.1158/1078-0432.CCR-15-2380  0.32
2015 Zhuang ZN, Ju HQ, Aguilar M, Gocho T, Li H, Iida T, Lee H, Fan X, Zhou H, Ling J, Li Z, Fu J, Wu M, Li M, Melisi D, ... ... Chiao PJ, et al. IL-1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-κB Activation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26500238 DOI: 10.1158/1078-0432.CCR-14-3382  0.32
2014 Chang Z, Ju H, Ling J, Zhuang Z, Li Z, Wang H, Fleming JB, Freeman JW, Yu D, Huang P, Chiao PJ. Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis. Plos One. 9: e101452. PMID 25029561 DOI: 10.1371/journal.pone.0101452  0.32
2013 Zhang Y, Yang J, Cui X, Chen Y, Zhu VF, Hagan JP, Wang H, Yu X, Hodges SE, Fang J, Chiao PJ, Logsdon CD, Fisher WE, Brunicardi FC, Chen C, et al. A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth. Embo Molecular Medicine. 5: 1322-34. PMID 23857777 DOI: 10.1002/emmm.201302507  0.32
2013 Chang Z, Li Z, Wang X, Kang Y, Yuan Y, Niu J, Wang H, Chatterjee D, Fleming JB, Li M, Abbruzzese JL, Chiao PJ. Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 549-59. PMID 23340292 DOI: 10.1158/1078-0432.CCR-12-0032  0.4
2013 Zhang Y, Chen L, Yang J, Fleming JB, Chiao PJ, Logsdon CD, Li M. Study human pancreatic cancer in mice: how close are they? Biochimica Et Biophysica Acta. 1835: 110-8. PMID 23147198 DOI: 10.1016/j.bbcan.2012.11.001  0.32
2012 Ling J, Kang Y, Zhao R, Xia Q, Lee DF, Chang Z, Li J, Peng B, Fleming JB, Wang H, Liu J, Lemischka IR, Hung MC, Chiao PJ. KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 21: 105-20. PMID 22264792 DOI: 10.1016/j.ccr.2011.12.006  0.32
2010 Peng B, Ling J, Lee AJ, Wang Z, Chang Z, Jin W, Kang Y, Zhang R, Shim D, Wang H, Fleming JB, Zheng H, Sun SC, Chiao PJ. Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. Proceedings of the National Academy of Sciences of the United States of America. 107: 15193-8. PMID 20696914 DOI: 10.1073/pnas.1005533107  0.32
2009 Li Z, Chang Z, Chiao LJ, Kang Y, Xia Q, Zhu C, Fleming JB, Evans DB, Chiao PJ. TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation. Cancer Research. 69: 7851-9. PMID 19773448 DOI: 10.1158/0008-5472.CAN-08-4002  0.32
2009 Uwagawa T, Chiao PJ, Gocho T, Hirohara S, Misawa T, Yanaga K. Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation. Anticancer Research. 29: 3173-8. PMID 19661331  0.32
2009 Melisi D, Niu J, Chang Z, Xia Q, Peng B, Ishiyama S, Evans DB, Chiao PJ. Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB. Molecular Cancer Research : McR. 7: 624-33. PMID 19435817 DOI: 10.1158/1541-7786.MCR-08-0201  0.4
2008 Melisi D, Ishiyama S, Sclabas GM, Fleming JB, Xia Q, Tortora G, Abbruzzese JL, Chiao PJ. LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis. Molecular Cancer Therapeutics. 7: 829-40. PMID 18413796 DOI: 10.1158/1535-7163.MCT-07-0337  0.4
2007 Xie X, Xia W, Li Z, Kuo HP, Liu Y, Li Z, Ding Q, Zhang S, Spohn B, Yang Y, Wei Y, Lang JY, Evans DB, Chiao PJ, Abbruzzese JL, et al. Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. Cancer Cell. 12: 52-65. PMID 17613436 DOI: 10.1016/j.ccr.2007.05.009  0.32
2007 Uwagawa T, Li Z, Chang Z, Xia Q, Peng B, Sclabas GM, Ishiyama S, Hung MC, Evans DB, Abbruzzese JL, Chiao PJ. Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. Cancer. 109: 2142-53. PMID 17410536 DOI: 10.1002/cncr.22658  0.4
2007 Niu J, Chang Z, Peng B, Xia Q, Lu W, Huang P, Tsao MS, Chiao PJ. Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. The Journal of Biological Chemistry. 282: 6001-11. PMID 17200110 DOI: 10.1074/jbc.M606878200  0.4
2006 Gao Z, He Q, Peng B, Chiao PJ, Ye J. Regulation of nuclear translocation of HDAC3 by IkappaBalpha is required for tumor necrosis factor inhibition of peroxisome proliferator-activated receptor gamma function. The Journal of Biological Chemistry. 281: 4540-7. PMID 16371367 DOI: 10.1074/jbc.M507784200  0.32
2005 Yokoi K, Kim SJ, Thaker P, Yazici S, Nam DH, He J, Sasaki T, Chiao PJ, Sclabas GM, Abbruzzese JL, Hamilton SR, Fidler IJ. Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. Neoplasia (New York, N.Y.). 7: 696-704. PMID 16026649  0.4
2005 Qian J, Niu J, Li M, Chiao PJ, Tsao MS. In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Research. 65: 5045-53. PMID 15958547 DOI: 10.1158/0008-5472.CAN-04-3208  0.4
2005 Sclabas GM, Uwagawa T, Schmidt C, Hess KR, Evans DB, Abbruzzese JL, Chiao PJ. Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin. Cancer. 103: 2485-90. PMID 15861417 DOI: 10.1002/cncr.21075  0.4
2005 Sclabas GM, Fujioka S, Schmidt C, Li Z, Frederick WA, Yang W, Yokoi K, Evans DB, Abbruzzese JL, Hess KR, Zhang W, Fidler IJ, Chiao PJ. Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 440-9. PMID 15701826  0.4
2005 Li Z, Niu J, Uwagawa T, Peng B, Chiao PJ. Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response. The Journal of Biological Chemistry. 280: 16843-50. PMID 15671037 DOI: 10.1074/jbc.M410119200  0.4
2004 Fujioka S, Niu J, Schmidt C, Sclabas GM, Peng B, Uwagawa T, Li Z, Evans DB, Abbruzzese JL, Chiao PJ. NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity. Molecular and Cellular Biology. 24: 7806-19. PMID 15314185 DOI: 10.1128/MCB.24.17.7806-7819.2004  0.4
2004 Li Z, Sclabas GM, Peng B, Hess KR, Abbruzzese JL, Evans DB, Chiao PJ. Overexpression of synuclein-gamma in pancreatic adenocarcinoma. Cancer. 101: 58-65. PMID 15221989 DOI: 10.1002/cncr.20321  0.4
2004 Fujioka S, Schmidt C, Sclabas GM, Li Z, Pelicano H, Peng B, Yao A, Niu J, Zhang W, Evans DB, Abbruzzese JL, Huang P, Chiao PJ. Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. The Journal of Biological Chemistry. 279: 27549-59. PMID 15102862 DOI: 10.1074/jbc.M313435200  0.4
2004 Niu J, Li Z, Peng B, Chiao PJ. Identification of an autoregulatory feedback pathway involving interleukin-1alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells. The Journal of Biological Chemistry. 279: 16452-62. PMID 14679213 DOI: 10.1074/jbc.M309789200  0.4
2003 Schmidt C, Peng B, Li Z, Sclabas GM, Fujioka S, Niu J, Schmidt-Supprian M, Evans DB, Abbruzzese JL, Chiao PJ. Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. Molecular Cell. 12: 1287-300. PMID 14636585  0.4
2003 Sclabas GM, Fujioka S, Schmidt C, Evans DB, Chiao PJ. NF-kappaB in pancreatic cancer. International Journal of Gastrointestinal Cancer. 33: 15-26. PMID 12909735 DOI: 10.1385/IJGC:33:1:15  0.4
2003 Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ. Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. Oncogene. 22: 1365-70. PMID 12618762 DOI: 10.1038/sj.onc.1206323  0.4
2003 Sclabas GM, Fujioka S, Schmidt C, Fan Z, Evans DB, Chiao PJ. Restoring apoptosis in pancreatic cancer cells by targeting the nuclear factor-kappaB signaling pathway with the anti-epidermal growth factor antibody IMC-C225. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 7: 37-43; discussion 43. PMID 12559183  0.4
2003 Fujioka S, Sclabas GM, Schmidt C, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ. Function of nuclear factor kappaB in pancreatic cancer metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 346-54. PMID 12538487  0.4
2002 Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3628-38. PMID 12429655  0.32
2002 Chiao PJ, Na R, Niu J, Sclabas GM, Dong Q, Curley SA. Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells. Cancer. 95: 1696-705. PMID 12365017 DOI: 10.1002/cncr.10829  0.4
2002 Dong QG, Sclabas GM, Fujioka S, Schmidt C, Peng B, Wu T, Tsao MS, Evans DB, Abbruzzese JL, McDonnell TJ, Chiao PJ. The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. Oncogene. 21: 6510-9. PMID 12226754 DOI: 10.1038/sj.onc.1205848  0.4
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