Gary A. Koretzky - Publications

University of Pennsylvania, Philadelphia, PA, United States 
Cell Biology, Immunology

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Carty SA, Gohil M, Banks LB, Cotton RM, Johnson ME, Stelekati E, Wells AD, Wherry EJ, Koretzky GA, Jordan MS. The Loss of TET2 Promotes CD8(+) T Cell Memory Differentiation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29150566 DOI: 10.4049/jimmunol.1700559  0.6
2015 Lieberman SM, Kreiger PA, Koretzky GA. Reversible lacrimal gland-protective regulatory T-cell dysfunction underlies male-specific autoimmune dacryoadenitis in the non-obese diabetic mouse model of Sjögren syndrome. Immunology. 145: 232-41. PMID 25581706 DOI: 10.1111/imm.12439  0.56
2014 Carty SA, Koretzky GA, Jordan MS. Interleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation. Plos One. 9: e106659. PMID 25207963 DOI: 10.1371/journal.pone.0106659  0.6
2014 Min SH, Suzuki A, Stalker TJ, Zhao L, Wang Y, McKennan C, Riese MJ, Guzman JF, Zhang S, Lian L, Joshi R, Meng R, Seeholzer SH, Choi JK, Koretzky G, et al. Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice. Nature Communications. 5: 4691. PMID 25178411 DOI: 10.1038/ncomms5691  0.56
2014 Kim JS, Smith-Garvin JE, Koretzky GA, Jordan MS. Retraction. The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells. The Journal of Experimental Medicine. 211: 1919. PMID 25113971 DOI: 10.1084/jem.2011068007292014r  0.6
2013 Joshi RP, Schmidt AM, Das J, Pytel D, Riese MJ, Lester M, Diehl JA, Behrens EM, Kambayashi T, Koretzky GA. The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling. Science Signaling. 6: ra102. PMID 24280043 DOI: 10.1126/scisignal.2004373  0.56
2013 Kim JS, Sklarz T, Banks LB, Gohil M, Waickman AT, Skuli N, Krock BL, Luo CT, Hu W, Pollizzi KN, Li MO, Rathmell JC, Birnbaum MJ, Powell JD, Jordan MS, ... Koretzky GA, et al. Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways. Nature Immunology. 14: 611-8. PMID 23644504 DOI: 10.1038/ni.2607  0.56
2013 Riese MJ, Wang LC, Moon EK, Joshi RP, Ranganathan A, June CH, Koretzky GA, Albelda SM. Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases. Cancer Research. 73: 3566-77. PMID 23576561 DOI: 10.1158/0008-5472.CAN-12-3874  0.56
2013 Joshi RP, Koretzky GA. Diacylglycerol kinases: regulated controllers of T cell activation, function, and development. International Journal of Molecular Sciences. 14: 6649-73. PMID 23531532 DOI: 10.3390/ijms14046649  1
2012 Martínez-Moreno M, García-Liévana J, Soutar D, Torres-Ayuso P, Andrada E, Zhong XP, Koretzky GA, Mérida I, Ávila-Flores A. FoxO-dependent regulation of diacylglycerol kinase α gene expression. Molecular and Cellular Biology. 32: 4168-80. PMID 22890845 DOI: 10.1128/MCB.00654-12  0.36
2012 Lee D, Kim J, Baker RG, Koretzky GA, Hammer DA. SLP-76 is required for optimal CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow. European Journal of Immunology. 42: 2736-43. PMID 22806433 DOI: 10.1002/eji.201142303  0.56
2012 Lee D, Kim J, Beste MT, Koretzky GA, Hammer DA. Diacylglycerol kinase zeta negatively regulates CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 606-14. PMID 22546945 DOI: 10.1039/c2ib00002d  0.56
2012 Bobrovnikova-Marjon E, Pytel D, Riese MJ, Vaites LP, Singh N, Koretzky GA, Witze ES, Diehl JA. PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation. Molecular and Cellular Biology. 32: 2268-78. PMID 22493067 DOI: 10.1128/MCB.00063-12  0.56
2012 Beste MT, Lee D, King MR, Koretzky GA, Hammer DA. An integrated stochastic model of "inside-out" integrin activation and selective T-lymphocyte recruitment. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 2225-37. PMID 22149624 DOI: 10.1021/la203803e  0.56
2011 Burns JC, Corbo E, Degen J, Gohil M, Anterasian C, Schraven B, Koretzky GA, Kliche S, Jordan MS. The SLP-76 Src homology 2 domain is required for T cell development and activation. Journal of Immunology (Baltimore, Md. : 1950). 187: 4459-66. PMID 21949020 DOI: 10.4049/jimmunol.0903379  0.56
2011 Kim JS, Smith-Garvin JE, Koretzky GA, Jordan MS. The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells. The Journal of Experimental Medicine. 208: 2201-7. PMID 21948082 DOI: 10.1084/jem.20110680  0.6
2011 Sela M, Bogin Y, Beach D, Oellerich T, Lehne J, Smith-Garvin JE, Okumura M, Starosvetsky E, Kosoff R, Libman E, Koretzky G, Kambayashi T, Urlaub H, Wienands J, Chernoff J, et al. Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells Embo Journal. 30: 3160-3172. PMID 21725281 DOI: 10.1038/emboj.2011.213  0.56
2011 Chang JT, Ciocca ML, Kinjyo I, Palanivel VR, McClurkin CE, Dejong CS, Mooney EC, Kim JS, Steinel NC, Oliaro J, Yin CC, Florea BI, Overkleeft HS, Berg LJ, Russell SM, ... Koretzky GA, et al. Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity. 34: 492-504. PMID 21497118 DOI: 10.1016/j.immuni.2011.03.017  0.6
2011 Gordon SM, Carty SA, Kim JS, Zou T, Smith-Garvin J, Alonzo ES, Haimm E, Sant'Angelo DB, Koretzky GA, Reiner SL, Jordan MS. Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 4573-8. PMID 21383242 DOI: 10.4049/jimmunol.1100037  0.56
2011 Riese MJ, Grewal J, Das J, Zou T, Patil V, Chakraborty AK, Koretzky GA. Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses. The Journal of Biological Chemistry. 286: 5254-65. PMID 21138839 DOI: 10.1074/jbc.M110.171884  0.56
2010 Zou T, May RM, Koretzky GA. Understanding signal integration through targeted mutations of an adapter protein. Febs Letters. 584: 4901-9. PMID 20965179 DOI: 10.1016/j.febslet.2010.10.025  0.56
2010 Smith-Garvin JE, Burns JC, Gohil M, Zou T, Kim JS, Maltzman JS, Wherry EJ, Koretzky GA, Jordan MS. T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool. Blood. 116: 5548-59. PMID 20847203 DOI: 10.1182/blood-2010-06-292748  0.56
2010 Kambayashi T, Okumura M, Baker RG, Hsu CJ, Baumgart T, Zhang W, Koretzky GA. Independent and cooperative roles of adaptor molecules in proximal signaling during FcepsilonRI-mediated mast cell activation. Molecular and Cellular Biology. 30: 4188-96. PMID 20606011 DOI: 10.1128/MCB.00305-10  0.56
2010 Jordan MS, Koretzky GA. Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76. Cold Spring Harbor Perspectives in Biology. 2: a002501. PMID 20452948 DOI: 10.1101/cshperspect.a002501  0.6
2010 Bertozzi CC, Schmaier AA, Mericko P, Hess PR, Zou Z, Chen M, Chen CY, Xu B, Lu MM, Zhou D, Sebzda E, Santore MT, Merianos DJ, Stadtfeld M, Flake AW, ... ... Koretzky GA, et al. Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood. 116: 661-70. PMID 20363774 DOI: 10.1182/blood-2010-02-270876  0.56
2010 Juntilla MM, Patil VD, Calamito M, Joshi RP, Birnbaum MJ, Koretzky GA. AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species. Blood. 115: 4030-8. PMID 20354168 DOI: 10.1182/blood-2009-09-241000  0.56
2010 Thiel AT, Blessington P, Zou T, Feather D, Wu X, Yan J, Zhang H, Liu Z, Ernst P, Koretzky GA, Hua X. MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele. Cancer Cell. 17: 148-59. PMID 20159607 DOI: 10.1016/j.ccr.2009.12.034  0.56
2010 Calamito M, Juntilla MM, Thomas M, Northrup DL, Rathmell J, Birnbaum MJ, Koretzky G, Allman D. Akt1 and Akt2 promote peripheral B-cell maturation and survival. Blood. 115: 4043-50. PMID 20042722 DOI: 10.1182/blood-2009-09-241638  0.56
2010 Alonzo ES, Gottschalk RA, Das J, Egawa T, Hobbs RM, Pandolfi PP, Pereira P, Nichols KE, Koretzky GA, Jordan MS, Sant'Angelo DB. Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3. Journal of Immunology (Baltimore, Md. : 1950). 184: 1268-79. PMID 20038637 DOI: 10.4049/jimmunol.0903218  0.56
2010 Sonnenberg GF, Mangan PR, Bezman NA, Sekiguchi DR, Luning Prak ET, Erikson J, Maltzman JS, Jordan MS, Koretzky GA. Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production. Blood. 115: 2186-95. PMID 20029045 DOI: 10.1182/blood-2009-08-237438  0.56
2009 Epstein JA, Turka LA, Birnbaum M, Koretzky G. The physician's voice in the health care debate. The Journal of Clinical Investigation. 119: 2846. PMID 20069703 DOI: 10.1172/JCI40970  0.56
2009 Kambayashi T, Larosa DF, Silverman MA, Koretzky GA. Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation. Immunological Reviews. 232: 99-114. PMID 19909359 DOI: 10.1111/j.1600-065X.2009.00825.x  0.56
2009 Lenox LE, Kambayashi T, Okumura M, Prieto C, Sauer K, Bunte RM, Jordan MS, Koretzky GA, Nichols KE. Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritis. The Journal of Allergy and Clinical Immunology. 124: 1088-98. PMID 19895996 DOI: 10.1016/j.jaci.2009.08.038  0.56
2009 Yin B, Savic V, Juntilla MM, Bredemeyer AL, Yang-Iott KS, Helmink BA, Koretzky GA, Sleckman BP, Bassing CH. Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination. The Journal of Experimental Medicine. 206: 2625-39. PMID 19887394 DOI: 10.1084/jem.20091320  0.56
2009 Baker RG, Hsu CJ, Lee D, Jordan MS, Maltzman JS, Hammer DA, Baumgart T, Koretzky GA. The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells. Molecular and Cellular Biology. 29: 5578-89. PMID 19667077 DOI: 10.1128/MCB.00283-09  0.56
2009 Bezman NA, Baker RG, Lenox LE, Jordan MS, Koretzky GA. Cutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76. Journal of Immunology (Baltimore, Md. : 1950). 182: 5183-7. PMID 19380761 DOI: 10.4049/jimmunol.0802176  0.6
2009 Kambayashi T, Allenspach EJ, Chang JT, Zou T, Shoag JE, Reiner SL, Caton AJ, Koretzky GA. Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 182: 4686-95. PMID 19342644 DOI: 10.4049/jimmunol.0803180  0.56
2009 Kim K, Yang J, Zhong XP, Kim MH, Kim YS, Lee HW, Han S, Choi J, Han K, Seo J, Prescott SM, Topham MK, Bae YC, Koretzky G, Choi SY, et al. Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. The Embo Journal. 28: 1170-9. PMID 19229292 DOI: 10.1038/emboj.2009.44  0.36
2009 Abramovici H, Mojtabaie P, Parks RJ, Zhong XP, Koretzky GA, Topham MK, Gee SH. Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI. Molecular Biology of the Cell. 20: 2049-59. PMID 19211846 DOI: 10.1091/mbc.E07-12-1248  0.36
2009 Smith-Garvin JE, Koretzky GA, Jordan MS. T cell activation. Annual Review of Immunology. 27: 591-619. PMID 19132916 DOI: 10.1146/annurev.immunol.021908.132706  0.6
2009 Chiang YJ, Jordan MS, Horai R, Schwartzberg PL, Koretzky GA, Hodes RJ. Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation. The Journal of Biological Chemistry. 284: 4429-38. PMID 19074136 DOI: 10.1074/jbc.M808679200  0.6
2008 Bassiri H, Janice Yeo WC, Rothman J, Koretzky GA, Nichols KE. X-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses. Immunologic Research. 42: 145-59. PMID 18815745 DOI: 10.1007/s12026-008-8048-7  0.56
2008 Nunez-Cruz S, Yeo WC, Rothman J, Ojha P, Bassiri H, Juntilla M, Davidson D, Veillette A, Koretzky GA, Nichols KE. Differential requirement for the SAP-Fyn interaction during NK T cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 181: 2311-20. PMID 18684920  0.56
2008 Bezman NA, Lian L, Abrams CS, Brass LF, Kahn ML, Jordan MS, Koretzky GA. Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo. The Journal of Experimental Medicine. 205: 1775-88. PMID 18663126 DOI: 10.1084/jem.20080240  0.56
2008 Maltzman JS, Koretzky GA. CD3varepsilon: PeRuSing for positive selection. Nature Immunology. 9: 457-9. PMID 18425097 DOI: 10.1038/ni0508-457  0.32
2008 Jordan MS, Smith JE, Burns JC, Austin JE, Nichols KE, Aschenbrenner AC, Koretzky GA. Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. Immunity. 28: 359-69. PMID 18342008 DOI: 10.1016/j.immuni.2008.01.010  0.56
2008 Juntilla MM, Koretzky GA. Critical roles of the PI3K/Akt signaling pathway in T cell development. Immunology Letters. 116: 104-10. PMID 18243340 DOI: 10.1016/j.imlet.2007.12.008  1
2008 Kambayashi T, Baranski JD, Baker RG, Zou T, Allenspach EJ, Shoag JE, Jones PL, Koretzky GA. Indirect involvement of allergen-captured mast cells in antigen presentation. Blood. 111: 1489-96. PMID 18032707 DOI: 10.1182/blood-2007-07-102111  0.56
2008 Ramsey K, Luckashenak N, Koretzky GA, Clements JL. Impaired thymic selection in mice expressing altered levels of the SLP-76 adaptor protein. Journal of Leukocyte Biology. 83: 419-29. PMID 17965338 DOI: 10.1189/jlb.0507297  0.56
2008 Maltzman JS, Peterson EJ, Koretzky G. T-cell activation and tolerance Clinical Immunology. 211-223. DOI: 10.1016/B978-0-323-04404-2.10013-2  0.44
2007 Zhong XP, Olenchock BA, Koretzky GA. The role of diacylglycerol kinases in T cell anergy. Ernst Schering Foundation Symposium Proceedings. 139-49. PMID 18510102  0.36
2007 Jordan MS, Maltzman JS, Kliche S, Shabason J, Smith JE, Obstfeld A, Schraven B, Koretzky GA. In vivo disruption of T cell development by expression of a dominant-negative polypeptide designed to abolish the SLP-76/Gads interaction. European Journal of Immunology. 37: 2961-72. PMID 17823979 DOI: 10.1002/eji.200636855  0.6
2007 Bach TL, Chen QM, Kerr WT, Wang Y, Lian L, Choi JK, Wu D, Kazanietz MG, Koretzky GA, Zigmond S, Abrams CS. Phospholipase cbeta is critical for T cell chemotaxis. Journal of Immunology (Baltimore, Md. : 1950). 179: 2223-7. PMID 17675482 DOI: 10.4049/jimmunol.179.4.2223  0.56
2007 Bezman N, Koretzky GA. Compartmentalization of ITAM and integrin signaling by adapter molecules. Immunological Reviews. 218: 9-28. PMID 17624941 DOI: 10.1111/j.1600-065X.2007.00541.x  0.52
2007 Juntilla MM, Wofford JA, Birnbaum MJ, Rathmell JC, Koretzky GA. Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 104: 12105-10. PMID 17609365 DOI: 10.1073/pnas.0705285104  0.56
2007 Clemens RA, Lenox LE, Kambayashi T, Bezman N, Maltzman JS, Nichols KE, Koretzky GA. Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing. Journal of Immunology (Baltimore, Md. : 1950). 178: 4606-14. PMID 17372019  0.56
2007 Seet BT, Berry DM, Maltzman JS, Shabason J, Raina M, Koretzky GA, McGlade CJ, Pawson T. Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif. The Embo Journal. 26: 678-89. PMID 17235283 DOI: 10.1038/sj.emboj.7601535  0.56
2007 Bach TL, Kerr WT, Wang Y, Bauman EM, Kine P, Whiteman EL, Morgan RS, Williamson EK, Ostap EM, Burkhardt JK, Koretzky GA, Birnbaum MJ, Abrams CS. PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization. Blood. 109: 1147-55. PMID 17008542 DOI: 10.1182/blood-2006-02-001339  0.56
2007 Kasirer-Friede A, Moran B, Nagrampa-Orje J, Swanson K, Ruggeri ZM, Schraven B, Neel BG, Koretzky G, Shattil SJ. ADAP is required for normal αIIbβ3 activation by VWF/GP Ib-IX-V and other agonists Blood. 109: 1018-1025. PMID 17003372 DOI: 10.1182/blood-2006-05-022301  0.56
2006 Kahn ML, Koretzky GA. Integrins and ITAMs: more than just good neighbors. Nature Immunology. 7: 1286-8. PMID 17110948 DOI: 10.1038/ni1206-1286  0.56
2006 Olenchock BA, Guo R, Carpenter JH, Jordan M, Topham MK, Koretzky GA, Zhong XP. Disruption of diacylglycerol metabolism impairs the induction of T cell anergy Nature Immunology. 7: 1174-1181. PMID 17028587 DOI: 10.1038/ni1400  0.56
2006 Bunnell SC, Singer AL, Hong DI, Jacque BH, Jordan MS, Seminario MC, Barr VA, Koretzky GA, Samelson LE. Persistence of cooperatively stabilized signaling clusters drives T-cell activation. Molecular and Cellular Biology. 26: 7155-66. PMID 16980618 DOI: 10.1128/MCB.00507-06  0.56
2006 Sebzda E, Hibbard C, Sweeney S, Abtahian F, Bezman N, Clemens G, Maltzman JS, Cheng L, Liu F, Turner M, Tybulewicz V, Koretzky GA, Kahn ML. Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development. Developmental Cell. 11: 349-61. PMID 16950126 DOI: 10.1016/j.devcel.2006.07.007  0.52
2006 Abtahian F, Bezman N, Clemens R, Sebzda E, Cheng L, Shattil SJ, Kahn ML, Koretzky GA. Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells. Molecular and Cellular Biology. 26: 6936-49. PMID 16943434 DOI: 10.1128/MCB.01040-06  0.56
2006 Olenchock BA, Guo R, Silverman MA, Wu JN, Carpenter JH, Koretzky GA, Zhong XP. Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells. The Journal of Experimental Medicine. 203: 1471-80. PMID 16717114 DOI: 10.1084/jem.20052424  0.56
2006 Wu JN, Gheith S, Bezman NA, Liu QH, Fostel LV, Swanson AM, Freedman BD, Koretzky GA, Peterson EJ. Adhesion- and degranulation-promoting adapter protein is required for efficient thymocyte development and selection. Journal of Immunology (Baltimore, Md. : 1950). 176: 6681-9. PMID 16709827  0.56
2006 Koretzky GA, Abtahian F, Silverman MA. SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond. Nature Reviews. Immunology. 6: 67-78. PMID 16493428 DOI: 10.1038/nri1750  0.56
2006 Silverman MA, Shoag J, Wu J, Koretzky GA. Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells. Molecular and Cellular Biology. 26: 1826-38. PMID 16479002 DOI: 10.1128/MCB.26.5.1826-1838.2006  0.56
2006 Jordan MS, Sadler J, Austin JE, Finkelstein LD, Singer AL, Schwartzberg PL, Koretzky GA. Functional hierarchy of the N-terminal tyrosines of SLP-76. Journal of Immunology (Baltimore, Md. : 1950). 176: 2430-8. PMID 16456002  0.56
2005 Maltzman JS, Kovoor L, Clements JL, Koretzky GA. Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection. The Journal of Experimental Medicine. 202: 893-900. PMID 16186188 DOI: 10.1084/jem.20051128  0.56
2005 Nichols KE, Hom J, Gong SY, Ganguly A, Ma CS, Cannons JL, Tangye SG, Schwartzberg PL, Koretzky GA, Stein PL. Regulation of NKT cell development by SAP, the protein defective in XLP. Nature Medicine. 11: 340-5. PMID 15711562 DOI: 10.1038/nm1189  0.56
2004 Clemens RA, Newbrough SA, Chung EY, Gheith S, Singer AL, Koretzky GA, Peterson EJ. PRAM-1 is required for optimal integrin-dependent neutrophil function. Molecular and Cellular Biology. 24: 10923-32. PMID 15572693 DOI: 10.1128/MCB.24.24.10923-10932.2004  0.56
2004 Wu JN, Koretzky GA. The SLP-76 family of adapter proteins. Seminars in Immunology. 16: 379-93. PMID 15541653 DOI: 10.1016/j.smim.2004.08.018  0.32
2004 Cannons JL, Yu LJ, Hill B, Mijares LA, Dombroski D, Nichols KE, Antonellis A, Koretzky GA, Gardner K, Schwartzberg PL. SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1. Immunity. 21: 693-706. PMID 15539155 DOI: 10.1016/j.immuni.2004.09.012  0.56
2004 Artis D, Villarino A, Silverman M, He W, Thornton EM, Mu S, Summer S, Covey TM, Huang E, Yoshida H, Koretzky G, Goldschmidt M, Wu GD, de Sauvage F, Miller HR, et al. The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. Journal of Immunology (Baltimore, Md. : 1950). 173: 5626-34. PMID 15494513 DOI: 10.4049/jimmunol.173.9.5626  0.56
2004 Chiang YJ, Sommers CL, Jordan MS, Gu H, Samelson LE, Koretzky GA, Hodes RJ. Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice. The Journal of Experimental Medicine. 200: 25-34. PMID 15238603 DOI: 10.1084/jem.20040262  0.6
2004 Wu JN, Jordan MS, Silverman MA, Peterson EJ, Koretzky GA. Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function. Journal of Immunology (Baltimore, Md. : 1950). 172: 6768-74. PMID 15153494  0.56
2004 Singer AL, Bunnell SC, Obstfeld AE, Jordan MS, Wu JN, Myung PS, Samelson LE, Koretzky GA. Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function. The Journal of Biological Chemistry. 279: 15481-90. PMID 14722089 DOI: 10.1074/jbc.M313339200  0.56
2004 Nichols KE, Haines K, Myung PS, Newbrough S, Myers E, Jumaa H, Shedlock DJ, Shen H, Koretzky GA. Macrophage activation and Fcgamma receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors. Journal of Leukocyte Biology. 75: 541-52. PMID 14694181 DOI: 10.1189/jlb.0703312  0.56
2003 Zhong XP, Maltzman JS, Hainey EA, Koretzky GA. Transcriptional regulation of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa: dissection of key promoter elements. Journal of Immunology (Baltimore, Md. : 1950). 171: 6621-9. PMID 14662865  0.36
2003 Newbrough SA, Mocsai A, Clemens RA, Wu JN, Silverman MA, Singer AL, Lowell CA, Koretzky GA. SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils. Immunity. 19: 761-9. PMID 14614862 DOI: 10.1016/S1074-7613(03)00305-4  0.56
2003 Zhong XP, Hainey EA, Olenchock BA, Jordan MS, Maltzman JS, Nichols KE, Shen H, Koretzky GA. Enhanced T cell responses due to diacylglycerol kinase zeta deficiency. Nature Immunology. 4: 882-90. PMID 12883552 DOI: 10.1038/ni958  0.56
2003 Koretzky GA, Abtahian F, Derimanov GS, Dmowski SA, Guerriero A, Jordan MS, Maltzman JS, Olenchock BA, Singer AL, Wu JN, Zhong XP. Regulation of hematopoietic cell development and activation by adapter proteins. Immunologic Research. 27: 357-66. PMID 12857981 DOI: 10.1385/IR:27:2-3:357  0.56
2003 Maltzman JS, Koretzky GA. Azathioprine: old drug, new actions. The Journal of Clinical Investigation. 111: 1122-4. PMID 12697731 DOI: 10.1172/JCI18384  0.32
2003 Jordan MS, Singer AL, Koretzky GA. Adaptors as central mediators of signal transduction in immune cells. Nature Immunology. 4: 110-6. PMID 12555096 DOI: 10.1038/ni0203-110  0.6
2003 Abtahian F, Guerriero A, Sebzda E, Lu MM, Zhou R, Mocsai A, Myers EE, Huang B, Jackson DG, Ferrari VA, Tybulewicz V, Lowell CA, Lepore JJ, Koretzky GA, Kahn ML. Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk. Science (New York, N.Y.). 299: 247-51. PMID 12522250 DOI: 10.1126/science.1079477  0.56
2002 Kovacs B, Maus MV, Riley JL, Derimanov GS, Koretzky GA, June CH, Finkel TH. Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation. Proceedings of the National Academy of Sciences of the United States of America. 99: 15006-11. PMID 12419850 DOI: 10.1073/pnas.232058599  0.56
2002 Leo L, Di Paola J, Judd BA, Koretzky GA, Lentz SR. Role of the adapter protein SLP-76 in GPVI-dependent platelet procoagulant responses to collagen. Blood. 100: 2839-44. PMID 12351393 DOI: 10.1182/blood-2002-04-1234  0.56
2002 Zhong XP, Hainey EA, Olenchock BA, Zhao H, Topham MK, Koretzky GA. Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta. The Journal of Biological Chemistry. 277: 31089-98. PMID 12070163 DOI: 10.1074/jbc.M203818200  0.36
2002 Singer AL, Koretzky GA. Control of T cell function by positive and negative regulators. Science (New York, N.Y.). 296: 1639-40. PMID 12040176 DOI: 10.1126/science.1071551  0.44
2002 Judd BA, Myung PS, Obergfell A, Myers EE, Cheng AM, Watson SP, Pear WS, Allman D, Shattil SJ, Koretzky GA. Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling. The Journal of Experimental Medicine. 195: 705-17. PMID 11901197 DOI: 10.1084/jem.20011583  0.56
2001 O'Shea JJ, Johnston JA, Kehrl J, Koretzky G, Samelson LE. Key molecules involved in receptor-mediated lymphocyte activation Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. PMID 18432708 DOI: 10.1002/0471142735.im1109as44  0.56
2001 Koretzky GA, Myung PS. Positive and negative regulation of T-cell activation by adaptor proteins. Nature Reviews. Immunology. 1: 95-107. PMID 11905825 DOI: 10.1038/35100523  0.92
2001 Myung PS, Derimanov GS, Jordan MS, Punt JA, Liu QH, Judd BA, Meyers EE, Sigmund CD, Freedman BD, Koretzky GA. Differential requirement for SLP-76 domains in T cell development and function. Immunity. 15: 1011-26. PMID 11754821 DOI: 10.1016/S1074-7613(01)00253-9  0.56
2001 Tulasne D, Judd BA, Johansen M, Asazuma N, Best D, Brown EJ, Kahn M, Koretzky GA, Watson SP. C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination. Blood. 98: 3346-52. PMID 11719373 DOI: 10.1182/blood.V98.12.3346  0.56
2001 Judd BA, Koretzky GA. The role of the adapter molecule SLP-76 in platelet function. Oncogene. 20: 6291-9. PMID 11607831 DOI: 10.1038/sj.onc.1204772  0.56
2001 Peterson EJ, Woods ML, Dmowski SA, Derimanov G, Jordan MS, Wu JN, Myung PS, Liu QH, Pribila JT, Freedman BD, Shimizu Y, Koretzky GA. Coupling of the TCR to integrin activation by Slap-130/Fyb. Science (New York, N.Y.). 293: 2263-5. PMID 11567141 DOI: 10.1126/science.1063486  0.56
2001 Nichols KE, Koretzky GA, June CH. SAP: Natural inhibitor or grand SLAM of T cell activation? Nature Immunology. 2: 665-666. PMID 11477397 DOI: 10.1038/90595  0.56
2001 Allman D, Karnell FG, Punt JA, Bakkour S, Xu L, Myung P, Koretzky GA, Pui JC, Aster JC, Pear WS. Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells Journal of Experimental Medicine. 194: 99-106. PMID 11435476 DOI: 10.1084/jem.194.1.99  0.56
2001 Moog-Lutz C, Peterson EJ, Lutz PG, Eliason S, Cavé-Riant F, Singer A, Di Gioia Y, Dmowski S, Kamens J, Cayre YE, Koretzky G. PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells. The Journal of Biological Chemistry. 276: 22375-81. PMID 11301322 DOI: 10.1074/jbc.M011683200  0.56
2001 Izon DJ, Punt JA, Xu L, Karnell FG, Allman D, Myung PS, Boerth NJ, Pui JC, Koretzky GA, Pear WS. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength. Immunity. 14: 253-64. PMID 11290335 DOI: 10.1016/S1074-7613(01)00107-8  0.56
2001 Irie-Sasaki J, Sasaki T, Matsumoto W, Opavsky A, Cheng M, Welstead G, Griffiths E, Krawczyk C, Richardson CD, Aitken K, Iscove N, Koretzky G, Johnson P, Liu P, Rothstein DM, et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature. 409: 349-54. PMID 11201744 DOI: 10.1038/35053086  0.56
2001 Obergfell A, Judd BA, del Pozo MA, Schwartz MA, Koretzky GA, Shattil SJ. The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton. The Journal of Biological Chemistry. 276: 5916-23. PMID 11113155 DOI: 10.1074/jbc.M010639200  0.56
2000 Judd BA, Myung PS, Leng L, Obergfell A, Pear WS, Shattil SJ, Koretzky GA. Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 12056-61. PMID 11050236 DOI: 10.1073/pnas.97.22.12056  0.56
2000 Boerth NJ, Sadler JJ, Bauer DE, Clements JL, Gheith SM, Koretzky GA. Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling Journal of Experimental Medicine. 192: 1047-1058. PMID 11015445 DOI: 10.1084/jem.192.7.1047  0.56
2000 Myung PS, Clements JL, White DW, Malik ZA, Cowdery JS, Allen LH, Harty JT, Kusner DJ, Koretzky GA. In vitro and in vivo macrophage function can occur independently of SLP-76. International Immunology. 12: 887-97. PMID 10837416  0.56
2000 Myung PS, Boerthe NJ, Koretzky GA. Adapter proteins in lymphocyte antigen-receptor signaling. Current Opinion in Immunology. 12: 256-66. PMID 10781404  0.92
2000 Boerth NJ, Judd BA, Koretzky GA. Functional association between SLAP-130 and SLP-76 in Jurkat T cells. The Journal of Biological Chemistry. 275: 5143-52. PMID 10671560 DOI: 10.1074/jbc.275.7.5143  0.56
1999 Pasquet JM, Gross B, Quek L, Asazuma N, Zhang W, Sommers CL, Schweighoffer E, Tybulewicz V, Judd B, Lee JR, Koretzky G, Love PE, Samelson LE, Watson SP. LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI. Molecular and Cellular Biology. 19: 8326-34. PMID 10567557 DOI: 10.1128/MCB.19.12.8326  0.56
1999 Peterson EJ, Clements JL, Ballas ZK, Koretzky GA. NK cytokine secretion and cytotoxicity occur independently of the SLP-76 adaptor protein. European Journal of Immunology. 29: 2223-32. PMID 10427985 DOI: 10.1002/(SICI)1521-4141(199907)29:07<2223::AID-IMMU2223>3.0.CO;2-6  0.56
1999 Clements JL, Boerth NJ, Lee JR, Koretzky GA. Integration of T cell receptor-dependent signaling pathways by adapter proteins Annual Review of Immunology. 17: 89-108. PMID 10358754 DOI: 10.1146/annurev.immunol.17.1.89  0.56
1999 Cowdery JS, Boerth NJ, Norian LA, Myung PS, Koretzky GA. Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 162: 6770-5. PMID 10352297  0.92
1999 Clements JL, Koretzky GA. Recent developments in lymphocyte activation: Linking kinases to downstream signaling events Journal of Clinical Investigation. 103: 925-929. PMID 10194464 DOI: 10.1172/JCI6562  0.56
1999 Mallampalli RK, Peterson EJ, Carter AB, Salome RG, Mathur SN, Koretzky GA. TNF-alpha increases ceramide without inducing apoptosis in alveolar type II epithelial cells. The American Journal of Physiology. 276: L481-90. PMID 10070113 DOI: 10.1152/ajplung.1999.276.3.L481  0.56
1999 Gross BS, Lee JR, Clements JL, Turner M, Tybulewicz VL, Findell PR, Koretzky GA, Watson SP. Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets. The Journal of Biological Chemistry. 274: 5963-71. PMID 10026222 DOI: 10.1074/jbc.274.9.5963  0.56
1999 Clements JL, Lee JR, Gross B, Yang B, Olson JD, Sandra A, Watson SP, Lentz SR, Koretzky GA. Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice Journal of Clinical Investigation. 103: 19-25. PMID 9884330  0.56
1998 Lee JR, Koretzky GA. Production of reactive oxygen intermediates following CD40 ligation correlates with c-Jun N-terminal kinase activation and IL-6 secretion in murine B lymphocytes European Journal of Immunology. 28: 4188-4197. PMID 9862355 DOI: 10.1002/(SICI)1521-4141(199812)28:12<4188::AID-IMMU4188>3.0.CO;2-B  0.56
1998 Binstadt BA, Billadeau DD, Jevremović D, Williams BL, Fang N, Yi T, Koretzky GA, Abraham RT, Leibson PJ. SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors. The Journal of Biological Chemistry. 273: 27518-23. PMID 9765283 DOI: 10.1074/jbc.273.42.27518  0.56
1998 Clements JL, Yang B, Ross-Barta SE, Eliason SL, Hrstka RF, Williamson RA, Koretzky GA. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development Science. 281: 416-419. PMID 9665885 DOI: 10.1126/science.281.5375.416  0.56
1998 Peterson EJ, Clements JL, Fang N, Koretzky GA. Adaptor proteins in lymphocyte antigen-receptor signaling. Current Opinion in Immunology. 10: 337-44. PMID 9638371 DOI: 10.1016/S0952-7915(98)80173-8  0.56
1998 Peterson EJ, Latinis KM, Koretzky GA. Molecular characterization of a CD95 signaling mutant. Arthritis and Rheumatism. 41: 1047-53. PMID 9627014 DOI: 10.1002/1529-0131(199806)41:6<1047::AID-ART11>3.0.CO;2-T  0.44
1998 Zhao H, Okada S, Pessin JE, Koretzky GA. Insulin receptor-mediated dissociation of Grb2 from Sos involves phosphorylation of Sos by kinase(s) other than extracellular signal-regulated kinase. The Journal of Biological Chemistry. 273: 12061-7. PMID 9575148 DOI: 10.1074/jbc.273.20.12061  0.36
1997 Zhao H, Li YY, Fucini RV, Ross SE, Pessin JE, Koretzky GA. T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK. The Journal of Biological Chemistry. 272: 21625-34. PMID 9261185 DOI: 10.1074/jbc.272.34.21625  0.36
1997 Musci MA, Hendricks-Taylor LR, Motto DG, Paskind M, Kamens J, Turck CW, Koretzky GA. Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases Journal of Biological Chemistry. 272: 11674-11677. PMID 9115214 DOI: 10.1074/jbc.272.18.11674  0.56
1996 Goldman F, Hohl RJ, Crabtree J, Lewis-Tibesar K, Koretzky G. Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras Blood. 88: 4611-4619. PMID 8977253  0.56
1996 Onodera H, Motto DG, Koretzky GA, Rothstein DM. Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase. The Journal of Biological Chemistry. 271: 22225-30. PMID 8703037 DOI: 10.1074/jbc.271.36.22225  0.56
1996 Sunden SLF, Carr LL, Clements JL, Motto DG, Koretzky GA. Polymorphism in and localization of the gene LCP2 (SLP-76) to chromosome 5q33.1-qter Genomics. 35: 269-270. PMID 8661136 DOI: 10.1006/geno.1996.0354  0.56
1996 Motto DG, Musci MA, Ross SE, Koretzky GA. Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase Cγ1 activation in T cells Molecular and Cellular Biology. 16: 2823-2829. PMID 8649391 DOI: 10.1128/MCB.16.6.2823  0.56
1996 Holt KH, Waters SB, Okada S, Yamauchi K, Decker SJ, Saltiel AR, Motto DG, Koretzky GA, Pessin JE. Epidermal growth factor receptor targeting prevents uncoupling of the Grb2-SOS complex Journal of Biological Chemistry. 271: 8300-8306. PMID 8626525 DOI: 10.1074/jbc.271.14.8300  0.56
1995 Yang B, Jung D, Motto D, Meyer J, Koretzky G, Campbell KP. SH3 domain-mediated interaction of dystroglycan and Grb2. The Journal of Biological Chemistry. 270: 11711-4. PMID 7744812 DOI: 10.1074/jbc.270.20.11711  0.56
1995 Jackman JK, Motto DG, Sun Q, Tanemoto M, Turck CW, Peltz GA, Koretzky GA, Findell PR. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells Journal of Biological Chemistry. 270: 7029-7032. PMID 7706237 DOI: 10.1074/jbc.270.13.7029  0.56
1995 Waters SB, Holt KH, Ross SE, Syu LJ, Guan KL, Saltiel AR, Koretzky GA, Pessin JE. Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex Journal of Biological Chemistry. 270: 20883-20886. PMID 7673108 DOI: 10.1074/jbc.270.36.20883  0.56
1995 McCray PB, Armstrong K, Zabner J, Miller DW, Koretzky GA, Couture L, Robillard JE, Smith AE, Welsh MJ. Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo. The Journal of Clinical Investigation. 95: 2620-32. PMID 7539457 DOI: 10.1172/JCI117964  0.56
1994 Ross SE, Schraven B, Goldman FD, Crabtree J, Koretzky GA. The association between CD45 and LCK does not require CD4 or CD8 and is independent of T cell receptor stimulation Biochemical and Biophysical Research Communications. 198: 88-96. PMID 8292053 DOI: 10.1006/bbrc.1994.1013  0.56
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