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Year Citation  Score
2024 Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Schneider SM, Tang X, Raso MG, Jeter CR, Zal T, ... ... Watowich SS, et al. STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response. Leukemia. PMID 38467768 DOI: 10.1038/s41375-024-02218-6  0.356
2023 Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Tang X, Raso MG, Zal T, Clise-Dwyer K, Giancotti FG, ... ... Watowich SS, et al. STAT3 protects HSCs from intrinsic interferon signaling and loss of long-term blood-forming activity. Biorxiv : the Preprint Server For Biology. PMID 36798265 DOI: 10.1101/2023.02.10.528069  0.312
2022 Chrisikos TT, Zhou Y, Kahn LM, Patel B, Denne NL, Brooks A, Shen L, Wang J, Watowich SS. STAT3 Inhibits Autocrine IFN Signaling in Type I Conventional Dendritic Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 36038291 DOI: 10.4049/jimmunol.2101104  0.389
2022 Babcock RL, Zhou Y, Patel B, Chrisikos TT, Kahn LM, Dyevoich AM, Medik YB, Watowich SS. Regulation and function of Id2 in plasmacytoid dendritic cells. Molecular Immunology. 148: 6-17. PMID 35640521 DOI: 10.1016/j.molimm.2022.05.009  0.321
2021 Marie IJ, Brambilla L, Azzouz D, Chen Z, Baracho GV, Arnett A, Li HS, Liu W, Cimmino L, Chattopadhyay P, Silverman G, Watowich SS, Khor B, Levy D. Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome. Elife. 10. PMID 34378531 DOI: 10.7554/eLife.68371  0.377
2020 Deng S, Ramos-Castaneda M, Velasco WV, Clowers MJ, Gutierrez BA, Noble O, Dong Y, Zarghooni M, Alvarado L, Caetano MS, Yang S, Ostrin EJ, Behrens C, Wistuba II, Stabile LP, ... ... Watowich SS, et al. Interplay between Estrogen and Stat3/NF-κB Driven Immunomodulation in Lung Cancer. Carcinogenesis. PMID 32603404 DOI: 10.1093/Carcin/Bgaa064  0.317
2020 Wang J, Hasan F, Frey AC, Li HS, Park J, Pan K, Haymaker C, Bernatchez C, Lee DA, Watowich SS, Yee C. Histone deacetylase inhibitors and IL21 cooperate to reprogram human effector CD8+ T cells to memory T cells. Cancer Immunology Research. PMID 32213626 DOI: 10.1158/2326-6066.Cir-19-0619  0.395
2020 Chrisikos TT, Zhou Y, Li HS, Babcock RL, Wan X, Patel B, Newton K, Mancuso JJ, Watowich SS. STAT3 Inhibits CD103 cDC1 Vaccine Efficacy in Murine Breast Cancer. Cancers. 12. PMID 31947933 DOI: 10.3390/Cancers12010128  0.358
2020 Lulla AR, Akli S, Chrisikos TT, Pina MA, Zhou Y, Li H, Watowich SS, Keyomarsi K. Abstract P3-10-02: Neutrophil elastase as a therapeutic target to inhibit metastasis in breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-10-02  0.302
2019 Li Y, Yang JY, Xie X, Jie Z, Zhang L, Shi J, Lin D, Gu M, Zhou X, Li HS, Watowich SS, Jain A, Yun Jung S, Qin J, Cheng X, et al. Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization. Cell Research. PMID 31086255 DOI: 10.1038/S41422-019-0174-3  0.376
2019 Chu F, Li HS, Liu X, Cao J, Ma W, Ma Y, Weng J, Zhu Z, Cheng X, Wang Z, Liu J, Jiang ZY, Luong AU, Peng W, Wang J, ... ... Watowich SS, et al. CXCR5CD8 T cells are a distinct functional subset with an antitumor activity. Leukemia. PMID 31028278 DOI: 10.1038/S41375-019-0464-2  0.375
2019 Zuo X, Deguchi Y, Xu W, Liu Y, Li HS, Wei D, Tian R, Chen W, Xu M, Yang Y, Gao S, Jaoude JC, Liu F, Chrieki SP, Moussalli MJ, ... ... Watowich SS, et al. PPARD and Interferon gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice. Gastroenterology. PMID 30885780 DOI: 10.1053/J.Gastro.2019.03.018  0.324
2019 Yan J, Zhao Q, Gabrusiewicz K, Kong LY, Xia X, Wang J, Ott M, Xu J, Davis RE, Huo L, Rao G, Sun SC, Watowich SS, Heimberger AB, Li S. FGL2 promotes tumor progression in the CNS by suppressing CD103 dendritic cell differentiation. Nature Communications. 10: 448. PMID 30683885 DOI: 10.1038/S41467-018-08271-X  0.349
2018 Caetano MS, Hassane M, Van HT, Bugarin E, Cumpian AM, McDowell CL, Cavazos CG, Zhang H, Deng S, Diao L, Wang J, Evans SE, Behrens C, Wistuba II, Fuqua SAW, ... ... Watowich SS, et al. Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer. Nature Communications. 9: 4589. PMID 30389925 DOI: 10.1038/S41467-018-07042-Y  0.314
2018 Cardona SM, Kim SV, Church KA, Torres VO, Cleary IA, Mendiola AS, Saville SP, Watowich SS, Parker-Thornburg J, Soto-Ospina A, Araque P, Ransohoff RM, Cardona AE. Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1 Variant. Frontiers in Cellular Neuroscience. 12: 365. PMID 30386211 DOI: 10.3389/Fncel.2018.00365  0.358
2018 Nicholson SE, Watowich SS. Introduction to the Special Issue: The tumor microenvironment and molecular regulation of innate immune cells. Molecular Immunology. PMID 30318379 DOI: 10.1016/J.Molimm.2018.10.009  0.304
2018 Chrisikos TT, Zhou Y, Slone N, Babcock R, Watowich SS, Li HS. Molecular regulation of dendritic cell development and function in homeostasis, inflammation, and cancer. Molecular Immunology. PMID 29549977 DOI: 10.1016/J.Molimm.2018.01.014  0.33
2018 Zhang H, Li HS, Hillmer EJ, Zhao Y, Chrisikos TT, Hu H, Wu X, Thompson EJ, Clise-Dwyer K, Millerchip KA, Wei Y, Puebla-Osorio N, Kaushik S, Santos MA, Wang B, ... ... Watowich SS, et al. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463696 DOI: 10.1073/Pnas.1713889115  0.452
2018 Fan F, Wang R, Boulbes DR, Zhang H, Watowich SS, Xia L, Ye X, Bhattacharya R, Ellis LM. Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway. Plos One. 13: e0190070. PMID 29293549 DOI: 10.1371/Journal.Pone.0190070  0.348
2017 Caetano MS, Van H, Bugarin E, Cumpian A, McDowell CL, Zhang H, Evans SE, Watowich S, Kadara H, Moghaddam SJ. Abstract 3974: Gender specific function of epithelial IL-6-STAT3 pathway in K-ras mutant lung cancer Cancer Research. 77: 3974-3974. DOI: 10.1158/1538-7445.Am2017-3974  0.382
2017 Fan F, Wang R, Boulbes DR, Zhang H, Watowich SS, Bhattacharya R, Xia L, Ye X, Ellis LM. Abstract 2887: Macrophage conditioned medium promotes colon cancer stem cell phenotype via the hedgehog signaling pathway Cancer Research. 77: 2887-2887. DOI: 10.1158/1538-7445.Am2017-2887  0.387
2016 Li HS, Liu C, Xiao Y, Chu F, Liang X, Peng W, Hu J, Neelapu SS, Sun SC, Hwu P, Watowich SS. Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells. Science Signaling. 9: ra94. PMID 27678219 DOI: 10.1126/Scisignal.Aaf3957  0.365
2016 Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, ... Watowich SS, et al. IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer. Cancer Research. PMID 27197187 DOI: 10.1158/0008-5472.Can-15-2840  0.386
2015 Mao F, Xu M, Zuo X, Yu J, Xu W, Moussalli MJ, Elias E, Li HS, Watowich SS, Shureiqi I. 15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2359-70. PMID 25713055 DOI: 10.1096/fj.14-264515  0.377
2015 Caetano MS, Cumpian AM, Gong L, Chang SH, Zhang H, Kadara HN, Sternberg C, Ferreira CG, Watowich SS, Moghaddam SJ. Abstract 413: Targeting IL-6 as a preventive and therapeutic strategy for K-ras mutant lung cancer Cancer Research. 75: 413-413. DOI: 10.1158/1538-7445.Am2015-413  0.372
2015 Zuo X, Mao F, Xu M, Xu W, Tian R, Moussalli MJMJ, Elias E, Li HS, Watowich SS, Shureiqi I. Abstract 1959: 15-lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway Cancer Research. 75: 1959-1959. DOI: 10.1158/1538-7445.Am2015-1959  0.447
2014 Zhang H, Hu H, Greeley N, Jin J, Matthews AJ, Ohashi E, Caetano MS, Li HS, Wu X, Mandal PK, McMurray JS, Moghaddam SJ, Sun SC, Watowich SS. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nature Communications. 5: 5798. PMID 25503582 DOI: 10.1038/Ncomms6798  0.484
2014 Watowich SS. Microbial messaging to the marrow. Blood. 124: 1379-80. PMID 25170108 DOI: 10.1182/Blood-2014-07-587345  0.365
2014 Zhu S, Phatarpekar PV, Denman CJ, Senyukov VV, Somanchi SS, Nguyen-Jackson HT, Mace EM, Freeman AF, Watowich SS, Orange JS, Holland SM, Lee DA. Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation. Blood. 124: 403-11. PMID 24891320 DOI: 10.1182/Blood-2013-05-499707  0.503
2014 Zou Q, Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC. USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses. Nature Immunology. 15: 562-70. PMID 24777531 DOI: 10.1038/Ni.2885  0.389
2014 Munoz J, Dhillon N, Janku F, Watowich SS, Hong DS. STAT3 inhibitors: finding a home in lymphoma and leukemia. The Oncologist. 19: 536-44. PMID 24705981 DOI: 10.1634/Theoncologist.2013-0407  0.418
2014 Li H, Jin J, Sun s, Watowich SS. Molecular Regulation of Adult Hematopoiesis By GATA-2 Blood. 124: 4337-4337. DOI: 10.1182/Blood.V124.21.4337.4337  0.397
2014 Caetano MS, Cumpian AM, Gong L, Ochoa CE, Chang SH, Zhang H, Watowich S, Sternberg C, Ferreira CG, Moghaddam SJ. Abstract A13: Pharmacologic targeting of IL-6 suppresses tumor progression in a non-small cell lung cancer mouse model with K-ras mutation through re-educating the tumor microenvironment. Clinical Cancer Research. 20: A13-A13. DOI: 10.1158/1078-0432.14Aacriaslc-A13  0.36
2013 Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C. The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nature Immunology. 14: 732-40. PMID 23727894 DOI: 10.1038/Ni.2633  0.477
2013 Liu C, Peng W, Xu C, Lou Y, Zhang M, Wargo JA, Chen JQ, Li HS, Watowich SS, Yang Y, Tompers Frederick D, Cooper ZA, Mbofung RM, Whittington M, Flaherty KT, et al. BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 393-403. PMID 23204132 DOI: 10.1158/1078-0432.Ccr-12-1626  0.303
2012 Li HS, Yang CY, Nallaparaju KC, Zhang H, Liu YJ, Goldrath AW, Watowich SS. The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development. Blood. 120: 4363-73. PMID 23033267 DOI: 10.1182/Blood-2012-07-441311  0.31
2012 Nguyen-Jackson HT, Li HS, Zhang H, Ohashi E, Watowich SS. G-CSF-activated STAT3 enhances production of the chemokine MIP-2 in bone marrow neutrophils. Journal of Leukocyte Biology. 92: 1215-25. PMID 23024284 DOI: 10.1189/Jlb.0312126  0.471
2012 Nurieva RI, Podd A, Chen Y, Alekseev AM, Yu M, Qi X, Huang H, Wen R, Wang J, Li HS, Watowich SS, Qi H, Dong C, Wang D. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. The Journal of Biological Chemistry. 287: 11234-9. PMID 22318729 DOI: 10.1074/Jbc.M111.324046  0.51
2012 Huang X, Gelbard A, Li HS, Rodríguez-Cruz TG, Lou Y, Liu C, Hailemichael Y, Nanda VGY, Davies MA, Liu Y, Watowich SS, Overwijk WW. Abstract 5396: Interferon-α receptor dependent and independent inhibition of type I interferon production in plasmacytoid dendritic cells from mice and melanoma patients Cancer Research. 72: 5396-5396. DOI: 10.1158/1538-7445.Am2012-5396  0.37
2011 Yang CY, Best JA, Knell J, Yang E, Sheridan AD, Jesionek AK, Li HS, Rivera RR, Lind KC, D'Cruz LM, Watowich SS, Murre C, Goldrath AW. The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nature Immunology. 12: 1221-9. PMID 22057289 DOI: 10.1038/Ni.2158  0.346
2011 Li HS, Gelbard A, Martinez GJ, Esashi E, Zhang H, Nguyen-Jackson H, Liu YJ, Overwijk WW, Watowich SS. Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response. Blood. 118: 3879-89. PMID 21828128 DOI: 10.1182/Blood-2011-04-349761  0.449
2011 Watowich SS. The erythropoietin receptor: molecular structure and hematopoietic signaling pathways. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 59: 1067-72. PMID 21307776 DOI: 10.2310/Jim.0B013E31820Fb28C  0.354
2010 Qualls JE, Neale G, Smith AM, Koo MS, DeFreitas AA, Zhang H, Kaplan G, Watowich SS, Murray PJ. Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling. Science Signaling. 3: ra62. PMID 20716764 DOI: 10.1126/Scisignal.2000955  0.492
2010 Zhang H, Nguyen-Jackson H, Panopoulos AD, Li HS, Murray PJ, Watowich SS. STAT3 controls myeloid progenitor growth during emergency granulopoiesis. Blood. 116: 2462-71. PMID 20581311 DOI: 10.1182/blood-2009-12-259630  0.787
2010 Nguyen-Jackson H, Panopoulos AD, Zhang H, Li HS, Watowich SS. STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction. Blood. 115: 3354-63. PMID 20185584 DOI: 10.1182/Blood-2009-08-240317  0.802
2010 Phatarpekar P, Zhu S, Denman CJ, Nguyen-Jackson N, Watowich SS, Cooper LJ, Lee DA. STAT3 Activation Promotes NK Cell Proliferation, NKG2D Expression, and NK Cell Antitumor Activity Blood. 116: 105-105. DOI: 10.1182/Blood.V116.21.105.105  0.472
2009 Hegde S, Ni S, He S, Yoon D, Feng GS, Watowich SS, Paulson RF, Hankey PA. Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiation. Oncogene. 28: 3349-59. PMID 19581930 DOI: 10.1038/Onc.2009.202  0.672
2009 Chung Y, Chang SH, Martinez GJ, Yang XO, Nurieva R, Kang HS, Ma L, Watowich SS, Jetten AM, Tian Q, Dong C. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity. 30: 576-87. PMID 19362022 DOI: 10.1016/J.Immuni.2009.02.007  0.484
2009 Speiran K, Bailey DP, Fernando J, Macey M, Barnstein B, Kolawole M, Curley D, Watowich SS, Murray PJ, Oskeritzian C, Ryan JJ. Endogenous suppression of mast cell development and survival by IL-4 and IL-10. Journal of Leukocyte Biology. 85: 826-36. PMID 19228815 DOI: 10.1189/Jlb.0708448  0.453
2009 Esashi E, Watowich SS. Dendritic cells: transcriptional control of plasmacytoid dendritic cell development by E2-2. Immunology and Cell Biology. 87: 1-2. PMID 19048021 DOI: 10.1038/Icb.2008.93  0.301
2009 Zhang H, Nguyen-Jackson H, Panopoulos A, Li HS, Murray PJ, Watowich S. STAT3 Controls Neutrophil Progenitor Growth and Differentiation During Emergency Granulopoiesis. Blood. 114: 3619-3619. DOI: 10.1182/Blood.V114.22.3619.3619  0.471
2008 Yamazaki T, Yang XO, Chung Y, Fukunaga A, Nurieva R, Pappu B, Martin-Orozco N, Kang HS, Ma L, Panopoulos AD, Craig S, Watowich SS, Jetten AM, Tian Q, Dong C. CCR6 regulates the migration of inflammatory and regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 8391-401. PMID 19050256 DOI: 10.4049/Jimmunol.181.12.8391  0.792
2008 Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, Ma L, Wang YH, Watowich SS, Jetten AM, Tian Q, Dong C. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity. 29: 138-49. PMID 18599325 DOI: 10.1016/J.Immuni.2008.05.009  0.492
2008 Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, Shah B, Chang SH, Schluns KS, Watowich SS, Feng XH, Jetten AM, Dong C. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity. 29: 44-56. PMID 18585065 DOI: 10.1016/J.Immuni.2008.05.007  0.483
2008 Panopoulos AD, Watowich SS. Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis. Cytokine. 42: 277-88. PMID 18400509 DOI: 10.1016/J.Cyto.2008.03.002  0.773
2008 Esashi E, Wang YH, Perng O, Qin XF, Liu YJ, Watowich SS. The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8. Immunity. 28: 509-20. PMID 18342552 DOI: 10.1016/J.Immuni.2008.02.013  0.463
2008 Kennedy Norton S, Barnstein B, Brenzovich J, Bailey DP, Kashyap M, Speiran K, Ford J, Conrad D, Watowich S, Moralle MR, Kepley CL, Murray PJ, Ryan JJ. IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 180: 2848-54. PMID 18292506 DOI: 10.4049/Jimmunol.180.5.2848  0.485
2008 Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity. 28: 29-39. PMID 18164222 DOI: 10.1016/J.Immuni.2007.11.016  0.79
2008 Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, Ma L, Wang Yh, Watowich SS, Jetten AM, Tian Q, Dong C. Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages (DOI: 10.1016/j.immuni.2008.05.009) Immunity. 29. DOI: 10.1016/J.Immuni.2008.07.010  0.345
2007 El Kasmi KC, Smith AM, Williams L, Neale G, Panopoulos AD, Panopolous A, Watowich SS, Häcker H, Foxwell BM, Murray PJ. Cutting edge: A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway. Journal of Immunology (Baltimore, Md. : 1950). 179: 7215-9. PMID 18025162 DOI: 10.4049/Jimmunol.179.11.7215  0.804
2007 Nurieva R, Yang XO, Martinez G, Zhang Y, Panopoulos AD, Ma L, Schluns K, Tian Q, Watowich SS, Jetten AM, Dong C. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature. 448: 480-3. PMID 17581589 DOI: 10.1038/Nature05969  0.786
2007 Kile BT, Panopoulos AD, Stirzaker RA, Hacking DF, Tahtamouni LH, Willson TA, Mielke LA, Henley KJ, Zhang JG, Wicks IP, Stevenson WS, Nurden P, Watowich SS, Justice MJ. Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia. Blood. 110: 2371-80. PMID 17515402 DOI: 10.1182/Blood-2006-10-055087  0.764
2007 Yang XO, Panopoulos AD, Nurieva R, Chang SH, Wang D, Watowich SS, Dong C. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. The Journal of Biological Chemistry. 282: 9358-63. PMID 17277312 DOI: 10.1074/Jbc.C600321200  0.807
2007 Nurieva R, Yang XO, Martinez G, Zhang Y, Panopoulos AD, Ma L, Schluns K, Tian Q, Watowich SS, Jetten AM, Dong C. 112 Essential Autocrine Regulation by IL-21 in the Generation of Inflammatory T Cells Cytokine. 39: 31-31. DOI: 10.1016/J.Cyto.2007.07.117  0.462
2006 El Kasmi KC, Holst J, Coffre M, Mielke L, de Pauw A, Lhocine N, Smith AM, Rutschman R, Kaushal D, Shen Y, Suda T, Donnelly RP, Myers MG, Alexander W, Vignali DA, ... Watowich SS, et al. General nature of the STAT3-activated anti-inflammatory response. Journal of Immunology (Baltimore, Md. : 1950). 177: 7880-8. PMID 17114459 DOI: 10.4049/Jimmunol.177.11.7880  0.465
2006 Panopoulos AD, Zhang L, Snow JW, Jones DM, Smith AM, El Kasmi KC, Liu F, Goldsmith MA, Link DC, Murray PJ, Watowich SS. STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils. Blood. 108: 3682-90. PMID 16888100 DOI: 10.1182/Blood-2006-02-003012  0.801
2006 Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE. Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. Angiogenesis. 9: 101-10. PMID 16871430 DOI: 10.1007/S10456-006-9038-9  0.459
2006 Zhang L, Badgwell DB, Bevers JJ, Schlessinger K, Murray PJ, Levy DE, Watowich SS. IL-6 signaling via the STAT3/SOCS3 pathway: functional analysis of the conserved STAT3 N-domain. Molecular and Cellular Biochemistry. 288: 179-89. PMID 16718380 DOI: 10.1007/S11010-006-9137-3  0.791
2005 Nishimoto A, Yu Y, Lu Z, Mao X, Ren Z, Watowich SS, Mills GB, Liao WS, Chen X, Bast RC, Luo RZ. A Ras homologue member I directly inhibits signal transducers and activators of transcription 3 translocation and activity in human breast and ovarian cancer cells. Cancer Research. 65: 6701-10. PMID 16061651 DOI: 10.1158/0008-5472.Can-05-0130  0.404
2005 Butcher BA, Kim L, Panopoulos AD, Watowich SS, Murray PJ, Denkers EY. IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages. Journal of Immunology (Baltimore, Md. : 1950). 174: 3148-52. PMID 15749841 DOI: 10.4049/Jimmunol.174.6.3148  0.789
2005 Gray MJ, Zhang J, Ellis LM, Semenza GL, Evans DB, Watowich SS, Gallick GE. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene. 24: 3110-20. PMID 15735682 DOI: 10.1038/Sj.Onc.1208513  0.355
2005 Wang L, Arcasoy MO, Watowich SS, Forget BG. Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells. Experimental Hematology. 33: 308-17. PMID 15730854 DOI: 10.1016/J.Exphem.2004.11.014  0.404
2005 Yoon D, Watowich SS, Prchal JT. Truncated Human EpoR Causes Polycythemia in Fetal Erythropoiesis through Stat5 Hyperactivation. Blood. 106: 567-567. DOI: 10.1182/Blood.V106.11.567.567  0.672
2004 Pauleau AL, Rutschman R, Lang R, Pernis A, Watowich SS, Murray PJ. Enhancer-mediated control of macrophage-specific arginase I expression. Journal of Immunology (Baltimore, Md. : 1950). 172: 7565-73. PMID 15187136 DOI: 10.4049/Jimmunol.172.12.7565  0.494
2004 Panopoulos AD, Yoon D, Zhang L, Watowich SS. Stat3 Is Required for In Vivo G-CSF-Responsiveness and Neutrophil Function. Blood. 104: 817-817. DOI: 10.1182/Blood.V104.11.817.817  0.711
2003 Yoon D, Watowich SS. Hematopoietic cell survival signals are elicited through non-tyrosine-containing sequences in the membrane-proximal region of the erythropoietin receptor (EPOR) by a Stat5-dependent pathway. Experimental Hematology. 31: 1310-6. PMID 14662339 DOI: 10.1016/J.Exphem.2003.08.009  0.695
2003 Sarna MK, Ingley E, Busfield SJ, Cull VS, Lepere W, McCarthy DJ, Wright MJ, Palmer GA, Chappell D, Sayer MS, Alexander WS, Hilton DJ, Starr R, Watowich SS, Bittorf T, et al. Differential regulation of SOCS genes in normal and transformed erythroid cells. Oncogene. 22: 3221-30. PMID 12761492 DOI: 10.1038/Sj.Onc.1206381  0.41
2002 Panopoulos AD, Bartos D, Zhang L, Watowich SS. Control of myeloid-specific integrin alpha Mbeta 2 (CD11b/CD18) expression by cytokines is regulated by Stat3-dependent activation of PU.1. The Journal of Biological Chemistry. 277: 19001-7. PMID 11889125 DOI: 10.1074/Jbc.M112271200  0.787
2002 Afrikanova I, Yeh E, Bartos D, Watowich SS, Longmore GD. Oncogene cooperativity in Friend erythroleukemia: erythropoietin receptor activation by the env gene of SFFV leads to transcriptional upregulation of PU.1, independent of SFFV proviral insertion. Oncogene. 21: 1272-84. PMID 11850847 DOI: 10.1038/Sj.Onc.1205183  0.357
2001 Kubatzky KF, Ruan W, Gurezka R, Cohen J, Ketteler R, Watowich SS, Neumann D, Langosch D, Klingmüller U. Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor. Current Biology : Cb. 11: 110-5. PMID 11231127 DOI: 10.1016/S0960-9822(01)00018-5  0.343
2000 Watowich SS, Mikami A, Busche RA, Xie X, Pharr PN, Longmore GD. Erythropoietin receptors that signal through Stat5 or Stat3 support fetal liver and adult erythropoiesis: Lack of specificity of Stat signals during red blood cell development Journal of Interferon and Cytokine Research. 20: 1065-1070. PMID 11152572 DOI: 10.1089/107999000750053726  0.434
2000 Wooten DK, Xie X, Bartos D, Busche RA, Longmore GD, Watowich SS. Cytokine signaling through Stat3 activates integrins, promotes adhesion, and induces growth arrest in the myeloid cell line 32D Journal of Biological Chemistry. 275: 26566-26575. PMID 10858439 DOI: 10.1074/Jbc.M003495200  0.474
1999 Watowich SS, Liu KD, Xie X, Lai SY, Mikami A, Longmore GD, Goldsmith MA. Oligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail Journal of Biological Chemistry. 274: 5415-5421. PMID 10026152 DOI: 10.1074/Jbc.274.9.5415  0.349
1999 Watowich SS, Xie X, Klingmuller U, Kere J, Lindlof M, Berglund S, de la Chapelle A. Erythropoietin Receptor Mutations Associated With Familial Erythrocytosis Cause Hypersensitivity to Erythropoietin in the Heterozygous State Blood. 94: 2530-2532. DOI: 10.1182/Blood.V94.7.2530.419K35_2530_2532  0.315
1997 Tarr K, Watowich SS, Longmore GD. Cell surface organization of the erythropoietin receptor complex differs depending on its mode of activation Journal of Biological Chemistry. 272: 9099-9107. PMID 9083037 DOI: 10.1074/Jbc.272.14.9099  0.31
1997 Watowich SS, Wu H, Socolovsky M, Klingmuller U, Constantinescu SN, Lodish HF. Cytokine receptor signal transduction and the control of hematopoietic cell development. Annual Review of Cell and Developmental Biology. 12: 91-128. PMID 8970723 DOI: 10.1146/Annurev.Cellbio.12.1.91  0.394
1997 Lodish HF, Hilton DJ, Klingmüller U, Watowich SS, Wu H. The erythropoietin receptor: biogenesis, dimerization, and intracellular signal transduction. Cold Spring Harbor Symposia On Quantitative Biology. 60: 93-104. PMID 8824381 DOI: 10.1101/Sqb.1995.060.01.012  0.307
1996 Hilton DJ, Watowich SS, Katz L, Lodish HF. Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor. The Journal of Biological Chemistry. 271: 4699-708. PMID 8617735 DOI: 10.1074/Jbc.271.9.4699  0.331
1992 Watowich SS, Yoshimura A, Longmore GD, Hilton DJ, Yoshimura Y, Lodish HF. Homodimerization and constitutive activation of the erythropoietin receptor Proceedings of the National Academy of Sciences of the United States of America. 89: 2140-2144. PMID 1312714 DOI: 10.1073/Pnas.89.6.2140  0.313
1991 Watowich SS, Morimoto RI, Lamb RA. Flux of the paramyxovirus hemagglutinin-neuraminidase glycoprotein through the endoplasmic reticulum activates transcription of the GRP78-BiP gene. Journal of Virology. 65: 3590-7. PMID 2041085 DOI: 10.1128/Jvi.65.7.3590-3597.1991  0.527
1988 Watowich SS, Morimoto RI. Complex regulation of heat shock- and glucose-responsive genes in human cells. Molecular and Cellular Biology. 8: 393-405. PMID 3275876 DOI: 10.1128/mcb.8.1.393-405.1988  0.522
Low-probability matches (unlikely to be authored by this person)
2014 Li HS, Watowich SS. Innate immune regulation by STAT-mediated transcriptional mechanisms. Immunological Reviews. 261: 84-101. PMID 25123278 DOI: 10.1111/imr.12198  0.298
1992 Ng DT, Watowich SS, Lamb RA. Analysis in vivo of GRP78-BiP/substrate interactions and their role in induction of the GRP78-BiP gene. Molecular Biology of the Cell. 3: 143-55. PMID 1550958 DOI: 10.1091/Mbc.3.2.143  0.293
2020 Zhou Y, Slone N, Chrisikos TT, Kyrysyuk O, Babcock RL, Medik YB, Li HS, Kleinerman ES, Watowich SS. Vaccine efficacy against primary and metastatic cancer with in vitro-generated CD103 conventional dendritic cells. Journal For Immunotherapy of Cancer. 8. PMID 32273347 DOI: 10.1136/Jitc-2019-000474  0.291
1994 Watowich SS, Hilton DJ, Lodish HF. Activation and inhibition of erythropoietin receptor function: role of receptor dimerization. Molecular and Cellular Biology. 14: 3535-49. PMID 8196600 DOI: 10.1128/Mcb.14.6.3535  0.288
1995 Hilton DJ, Watowich SS, Murray PJ, Lodish HF. Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor. Proceedings of the National Academy of Sciences of the United States of America. 92: 190-4. PMID 7816815 DOI: 10.1073/Pnas.92.1.190  0.287
2017 Kadmon CS, Landers CT, Li HS, Watowich SS, Rodriguez A, King KY. Microrna-22 controls interferon alpha production and erythroid maturation in response to infectious stress in mice. Experimental Hematology. PMID 28911907 DOI: 10.1016/J.Exphem.2017.09.001  0.287
1992 Lodish HF, Hilton D, Longmore G, Watowich SS, Yoshimura A. The erythropoietin receptor: Dimerization, activation, and tumorigenesis Cold Spring Harbor Symposia On Quantitative Biology. 57: 95-106. PMID 1339709 DOI: 10.1101/Sqb.1992.057.01.013  0.279
2014 Jin J, Hu H, Li HS, Yu J, Xiao Y, Brittain GC, Zou Q, Cheng X, Mallette FA, Watowich SS, Sun SC. Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity. Immunity. 40: 342-54. PMID 24656046 DOI: 10.1016/j.immuni.2014.02.006  0.272
2015 Huang X, Li J, Dorta-Estremera S, Di Domizio J, Anthony SM, Watowich SS, Popkin D, Liu Z, Brohawn P, Yao Y, Schluns KS, Lanier LL, Cao W. Neutrophils Regulate Humoral Autoimmunity by Restricting Interferon-γ Production via the Generation of Reactive Oxygen Species. Cell Reports. 12: 1120-32. PMID 26257170 DOI: 10.1016/J.Celrep.2015.07.021  0.271
2012 Li HS, Greeley N, Sugimoto N, Liu YJ, Watowich SS. miR-22 controls Irf8 mRNA abundance and murine dendritic cell development. Plos One. 7: e52341. PMID 23251709 DOI: 10.1371/Journal.Pone.0052341  0.27
1998 Levin I, Cohen J, Supino-Rosin L, Yoshimura A, Watowich SS, Neumann D. Identification of a cytoplasmic motif in the erythropoietin receptor required for receptor internalization. Febs Letters. 427: 164-70. PMID 9607304 DOI: 10.1016/S0014-5793(98)00414-1  0.268
2017 Ni L, Wang L, Yao C, Ni Z, Liu F, Gong C, Zhu X, Yan X, Watowich SS, Lee DA, Zhu S. The histone deacetylase inhibitor valproic acid inhibits NKG2D expression in natural killer cells through suppression of STAT3 and HDAC3. Scientific Reports. 7: 45266. PMID 28338101 DOI: 10.1038/srep45266  0.268
1993 Longmore GD, Watowich SS, Hilton DJ, Lodish HF. The erythropoietin receptor: Its role in hematopoiesis and myeloproliferative diseases Journal of Cell Biology. 123: 1305-1308. PMID 8253831 DOI: 10.1083/Jcb.123.6.1305  0.264
2016 Hillmer EJ, Zhang H, Li HS, Watowich SS. STAT3 signaling in immunity. Cytokine & Growth Factor Reviews. PMID 27185365 DOI: 10.1016/j.cytogfr.2016.05.001  0.262
2017 Xiao Y, Zou Q, Xie X, Liu T, Li HS, Jie Z, Jin J, Hu H, Manyam G, Zhang L, Cheng X, Wang H, Marie I, Levy DE, Watowich SS, et al. The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity. The Journal of Experimental Medicine. PMID 28356390 DOI: 10.1084/jem.20161524  0.261
2022 Yuan B, Clowers MJ, Velasco WV, Peng S, Peng Q, Shi Y, Ramos-Castaneda M, Zarghooni M, Yang S, Babcock RL, Chang SH, Heymach JV, Zhang J, Ostrin EJ, Watowich SS, et al. Targeting IL-1β as an immune preventive and therapeutic modality for K-ras mutant lung cancer. Jci Insight. PMID 35471938 DOI: 10.1172/jci.insight.157788  0.259
1995 Murray PJ, Watowich SS, Lodish HF, Young RA, Hilton DJ. Epitope tagging of the human endoplasmic reticulum HSP70 protein, BiP, to facilitate analysis of BiP--substrate interactions. Analytical Biochemistry. 229: 170-9. PMID 7485969 DOI: 10.1006/Abio.1995.1399  0.247
2010 Watowich SS, Liu YJ. Mechanisms regulating dendritic cell specification and development. Immunological Reviews. 238: 76-92. PMID 20969586 DOI: 10.1111/j.1600-065X.2010.00949.x  0.245
2019 Yan J, Zhao Q, Gabrusiewicz K, Kong LY, Xia X, Wang J, Ott M, Xu J, Davis RE, Huo L, Rao G, Sun SC, Watowich SS, Heimberger AB, Li S. Author Correction: FGL2 promotes tumor progression in the CNS by suppressing CD103 dendritic cell differentiation. Nature Communications. 10: 862. PMID 30770835 DOI: 10.1038/S41467-019-08770-5  0.244
1999 Watowich SS. Activation of erythropoietin signaling by receptor dimerization. The International Journal of Biochemistry & Cell Biology. 31: 1075-88. PMID 10582340 DOI: 10.1016/S1357-2725(99)00075-8  0.244
2022 Zhou Y, Medik YB, Patel B, Zamler DB, Chen S, Chapman T, Schneider S, Park EM, Babcock RL, Chrisikos TT, Kahn LM, Dyevoich AM, Pineda JE, Wong MC, Mishra AK, ... ... Watowich SS, et al. Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration. The Journal of Experimental Medicine. 220. PMID 36367776 DOI: 10.1084/jem.20221333  0.234
2012 Li HS, Watowich SS. A STATus report on DC development. Journal of Leukocyte Biology. 92: 445-59. PMID 22550127 DOI: 10.1189/jlb.0212052  0.232
2000 Cull V, Tilbrook PA, Adenan AS, Chappell D, Ingley E, Sarna MK, Palmer TN, Watowich SS, Klinken SP. Dominant action of mutated erythropoietin receptors on differentiation in vitro and erythroleukemia development in vivo. Oncogene. 19: 953-60. PMID 10702804 DOI: 10.1038/sj.onc.1203370  0.23
2019 Kettner NM, Vijayaraghavan S, Durak MG, Bui T, Kohansal M, Ha MJ, Liu B, Rao X, Wang J, Yi M, Carey JP, Chen X, Eckols TK, Raghavendra AS, Ibrahim NK, ... ... Watowich SS, et al. Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30867218 DOI: 10.1158/1078-0432.Ccr-18-3274  0.221
2015 Li HS, Jin J, Liang X, Matatall KA, Ma Y, Zhang H, Ullrich SE, King KY, Sun SC, Watowich SS. Loss of c-kit and bone marrow failure upon conditional removal of the GATA-2 C-terminal zinc finger domain in adult mice. European Journal of Haematology. PMID 26660446 DOI: 10.1111/ejh.12719  0.213
2019 Kettner NM, Vijayaraghavan S, Durak MG, Bui T, Kohansal M, Ha MJ, Liu B, Rao X, Yang J, Yi M, Carey JP, Chen X, Eckols TK, Raghavendra AS, Ibrahim NK, ... ... Watowich SS, et al. Abstract 323: Combined inhibition of STAT-3 & DNA repair in palbociclib resistant breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-323  0.213
2013 Li HS, Watowich SS. Diversification of dendritic cell subsets: Emerging roles for STAT proteins. Jak-Stat. 2: e25112. PMID 24416644 DOI: 10.4161/jkst.25112  0.205
2014 Li HS, Watowich SS. Assessing the development of murine plasmacytoid dendritic cells in Peyer's patches using adoptive transfer of hematopoietic progenitors. Journal of Visualized Experiments : Jove. PMID 24686788 DOI: 10.3791/51189  0.192
2022 Zamler DB, Shingu T, Kahn LM, Huntoon K, Kassab C, Ott M, Tomczak K, Liu J, Li Y, Lai I, Zorilla-Veloz R, Yee C, Rai K, Kim BY, Watowich SS, et al. Immune landscape of a genetically engineered murine model of glioma compared to human glioma by single-cell sequencing. Jci Insight. PMID 35653194 DOI: 10.1172/jci.insight.148990  0.189
2022 Bhagat A, Shrestha P, Jeyabal P, Peng Z, Watowich SS, Kleinerman ES. Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase. Frontiers in Oncology. 12: 947604. PMID 36033503 DOI: 10.3389/fonc.2022.947604  0.174
2023 Mahadevan KK, Dyevoich AM, Chen Y, Li B, Sugimoto H, Sockwell AM, McAndrews KM, Wang H, Shalapour S, Watowich SS, Kalluri R. Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer. Biorxiv : the Preprint Server For Biology. PMID 36945457 DOI: 10.1101/2023.03.05.531191  0.172
2023 Amit M, Baruch E, Nagarajan P, Gleber-Netto F, Rao X, Xie T, Akhter S, Adewale A, Islam S, Mattson B, Ferrarotto R, Wong M, Davies M, Jindal S, Basu S, ... ... Watowich S, et al. Inflammation induced by tumor-associated nerves promotes resistance to anti-PD-1 therapy in cancer patients and is targetable by IL-6 blockade. Research Square. PMID 37503252 DOI: 10.21203/rs.3.rs-3161761/v1  0.156
2021 Andrews MC, Duong CPM, Gopalakrishnan V, Iebba V, Chen WS, Derosa L, Khan MAW, Cogdill AP, White MG, Wong MC, Ferrere G, Fluckiger A, Roberti MP, Opolon P, Alou MT, ... ... Watowich S, et al. Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade. Nature Medicine. PMID 34239137 DOI: 10.1038/s41591-021-01406-6  0.151
2022 Wurster S, Watowich SS, Kontoyiannis DP. Checkpoint inhibitors as immunotherapy for fungal infections: Promises, challenges, and unanswered questions. Frontiers in Immunology. 13: 1018202. PMID 36389687 DOI: 10.3389/fimmu.2022.1018202  0.148
2023 Lulla AR, Akli S, Karakas C, Caruso JA, Warma LD, Fowlkes NW, Rao X, Wang J, Hunt KK, Watowich SS, Keyomarsi K. Neutrophil elastase remodels mammary tumors to facilitate lung metastasis. Molecular Cancer Therapeutics. PMID 37796181 DOI: 10.1158/1535-7163.MCT-23-0414  0.144
2023 Halsey TM, Thomas AS, Hayase T, Ma W, Abu-Sbeih H, Sun B, Parra ER, Jiang ZD, DuPont HL, Sanchez C, El-Himri R, Brown A, Flores I, McDaniel L, Ortega Turrubiates M, ... ... Watowich SS, et al. Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor-induced colitis. Science Translational Medicine. 15: eabq4006. PMID 37315113 DOI: 10.1126/scitranslmed.abq4006  0.13
2023 Wang Y, Jenq RR, Wargo JA, Watowich SS. Microbiome influencers of checkpoint blockade-associated toxicity. The Journal of Experimental Medicine. 220. PMID 36622383 DOI: 10.1084/jem.20220948  0.099
2023 Park JS, Gazzaniga FS, Wu M, Luthens AK, Gillis J, Zheng W, LaFleur MW, Johnson SB, Morad G, Park EM, Zhou Y, Watowich SS, Wargo JA, Freeman GJ, Kasper DL, et al. Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance. Nature. PMID 37138075 DOI: 10.1038/s41586-023-06026-3  0.08
2021 Spencer CN, McQuade JL, Gopalakrishnan V, McCulloch JA, Vetizou M, Cogdill AP, Khan MAW, Zhang X, White MG, Peterson CB, Wong MC, Morad G, Rodgers T, Badger JH, Helmink BA, ... ... Watowich SS, et al. Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response. Science (New York, N.Y.). 374: 1632-1640. PMID 34941392 DOI: 10.1126/science.aaz7015  0.029
2023 Park JS, Gazzaniga FS, Wu M, Luthens AK, Gillis J, Zheng W, LaFleur MW, Johnson SB, Morad G, Park EM, Zhou Y, Watowich SS, Wargo JA, Freeman GJ, Kasper DL, et al. Publisher Correction: Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance. Nature. PMID 37264079 DOI: 10.1038/s41586-023-06237-8  0.015
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