Kevin C. Kregel - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Recreation, Medicine and Surgery, Animal Physiology Biology, Molecular Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Haak JL, Kregel KC, Bloomer SA. Altered accumulation of hepatic mitochondrial antioxidant proteins with age and environmental heat stress. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 37881850 DOI: 10.1152/japplphysiol.00610.2023  0.764
2019 Bloomer SA, Moyer ED, Brown KE, Kregel KC. Aging results in accumulation of M1 and M2 hepatic macrophages and a differential response to gadolinium chloride. Histochemistry and Cell Biology. PMID 31691025 DOI: 10.1007/S00418-019-01827-Y  0.745
2019 Bloomer SA, Brown KE, Kregel KC. Renal iron accumulation and oxidative injury with aging: effects of treatment with an iron chelator. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30794723 DOI: 10.1093/Gerona/Glz055  0.757
2014 Bloomer SA, Kregel KC, Brown KE. Heat stress stimulates hepcidin mRNA expression and C/EBPα protein expression in aged rodent liver. Archives of Gerontology and Geriatrics. 58: 145-52. PMID 23993269 DOI: 10.1016/J.Archger.2013.07.012  0.807
2014 Bloomer SA, Han O, Kregel KC, Brown KE. Altered expression of iron regulatory proteins with aging is associated with transient hepatic iron accumulation after environmental heat stress. Blood Cells, Molecules & Diseases. 52: 19-26. PMID 23900040 DOI: 10.1016/J.Bcmd.2013.07.002  0.807
2014 Stauss H, Choudhary N, Moss A, Kregel K. Differential effects of clonidine and lisinopril on thermoregulatory and cardiovascular function during chronic exposure to exertional heat stress in rats (1104.30) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1104.30  0.416
2010 Crandall CG, Wilson TE, Kregel KC. Mechanisms and modulators of temperature regulation Journal of Applied Physiology. 109: 1219-1220. PMID 20724573 DOI: 10.1152/Japplphysiol.00921.2010  0.307
2010 Swanlund JM, Kregel KC, Oberley TD. Investigating autophagy: quantitative morphometric analysis using electron microscopy. Autophagy. 6: 270-7. PMID 19923921 DOI: 10.4161/Auto.6.2.10439  0.315
2009 Bloomer SA, Zhang HJ, Brown KE, Kregel KC. Differential regulation of hepatic heme oxygenase-1 protein with aging and heat stress. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 419-25. PMID 19196643 DOI: 10.1093/Gerona/Gln056  0.821
2009 Haak JL, Buettner GR, Spitz DR, Kregel KC. Aging augments mitochondrial susceptibility to heat stress. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R812-20. PMID 19144753 DOI: 10.1152/Ajpregu.90708.2008  0.809
2008 Swanlund JM, Kregel KC, Oberley TD. Autophagy following heat stress: the role of aging and protein nitration. Autophagy. 4: 936-9. PMID 18758235 DOI: 10.4161/Auto.6768  0.634
2008 Haak J, Kregel KC. 1962-2007: a cell stress odyssey. Novartis Foundation Symposium. 291: 3-15; discussion 15-. PMID 18575263 DOI: 10.1002/9780470754030.Ch2  0.76
2008 Oberley TD, Swanlund JM, Zhang HJ, Kregel KC. Aging results in increased autophagy of mitochondria and protein nitration in rat hepatocytes following heat stress. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 56: 615-27. PMID 18379016 DOI: 10.1369/Jhc.2008.950873  0.623
2008 Bloomer SA, Brown KE, Buettner GR, Kregel KC. Dysregulation of hepatic iron with aging: implications for heat stress-induced oxidative liver injury. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R1165-74. PMID 18272664 DOI: 10.1152/Ajpregu.00719.2007  0.792
2007 Kregel KC, Zhang HJ. An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R18-36. PMID 16917020 DOI: 10.1152/Ajpregu.00327.2006  0.397
2006 Ma X, Zhang HJ, Whiteis CA, Tian X, Davisson RL, Kregel KC, Abboud FM, Chapleau MW. NAD(P)H oxidase-induced oxidative stress in sympathetic ganglia of apolipoprotein E deficient mice. Autonomic Neuroscience : Basic & Clinical. 126: 285-91. PMID 16584925 DOI: 10.1016/J.Autneu.2006.02.005  0.313
2006 Zhang HJ, Doctrow SR, Oberley LW, Kregel KC. Chronic antioxidant enzyme mimetic treatment differentially modulates hyperthermia-induced liver HSP70 expression with aging. Journal of Applied Physiology (Bethesda, Md. : 1985). 100: 1385-91. PMID 16254069 DOI: 10.1152/Japplphysiol.01046.2005  0.617
2005 Morrison JP, Coleman MC, Aunan ES, Walsh SA, Spitz DR, Kregel KC. Thiol supplementation in aged animals alters antioxidant enzyme activity after heat stress. Journal of Applied Physiology (Bethesda, Md. : 1985). 99: 2271-7. PMID 16099896 DOI: 10.1152/Japplphysiol.00412.2005  0.769
2005 Morrison JP, Coleman MC, Aunan ES, Walsh SA, Spitz DR, Kregel KC. Aging reduces responsiveness to BSO- and heat stress-induced perturbations of glutathione and antioxidant enzymes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R1035-41. PMID 15947071 DOI: 10.1152/Ajpregu.00254.2005  0.789
2004 Zhang HJ, Doctrow SR, Xu L, Oberley LW, Beecher B, Morrison J, Oberley TD, Kregel KC. Redox modulation of the liver with chronic antioxidant enzyme mimetic treatment prevents age-related oxidative damage associated with environmental stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1547-9. PMID 15319374 DOI: 10.1096/Fj.04-1629Fje  0.752
2003 Zhang HJ, Xu L, Drake VJ, Xie L, Oberley LW, Kregel KC. Heat-induced liver injury in old rats is associated with exaggerated oxidative stress and altered transcription factor activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2293-5. PMID 14500545 DOI: 10.1096/Fj.03-0139Fje  0.585
2002 Kregel KC. Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 2177-86. PMID 11960972 DOI: 10.1152/Japplphysiol.01267.2001  0.575
2002 Zhang HJ, Drake VJ, Morrison JP, Oberley LW, Kregel KC. Selected contribution: Differential expression of stress-related genes with aging and hyperthermia. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 1762-9; discussion 1. PMID 11896047 DOI: 10.1152/Japplphysiol.00733.2001  0.736
2002 Lambert GP, Gisolfi CV, Berg DJ, Moseley PL, Oberley LW, Kregel KC. Selected contribution: Hyperthermia-induced intestinal permeability and the role of oxidative and nitrosative stress. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 1750-61; discussion . PMID 11896046 DOI: 10.1152/Japplphysiol.00787.2001  0.503
2002 Zhang HJ, Drake VJ, Xu L, Hu J, Domann FE, Oberley LW, Kregel KC. Redox regulation of adenovirus-induced AP-1 activation by overexpression of manganese-containing superoxide dismutase. Journal of Virology. 76: 355-63. PMID 11739700 DOI: 10.1128/Jvi.76.1.355-363.2002  0.331
2001 Hall DM, Sattler GL, Sattler CA, Zhang HJ, Oberley LW, Pitot HC, Kregel KC. Aging lowers steady-state antioxidant enzyme and stress protein expression in primary hepatocytes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 56: B259-67. PMID 11382788 DOI: 10.1093/Gerona/56.6.B259  0.455
2000 Massett MP, Lewis SJ, Stauss HM, Kregel KC. Vascular reactivity and baroreflex function during hyperthermia in conscious rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 279: R1282-9. PMID 11003994 DOI: 10.1152/Ajpregu.2000.279.4.R1282  0.412
2000 Hall DM, Xu L, Drake VJ, Oberley LW, Oberley TD, Moseley PL, Kregel KC. Aging reduces adaptive capacity and stress protein expression in the liver after heat stress Journal of Applied Physiology. 89: 749-759. PMID 10926662 DOI: 10.1152/Jappl.2000.89.2.749  0.63
2000 Hall DM, Oberley TD, Moseley PM, Buettner GR, Oberley LW, Weindruch R, Kregel KC. Caloric restriction improves thermotolerance and reduces hyperthermia- induced cellular damage in old rats Faseb Journal. 14: 78-86. PMID 10627282 DOI: 10.1096/Fasebj.14.1.78  0.585
1999 Massett MP, Lewis SJ, Bates JN, Kregel KC. Modulation of temperature-induced tone by vasoconstrictor agents. Journal of Applied Physiology (Bethesda, Md. : 1985). 86: 963-9. PMID 10066711 DOI: 10.1152/Jappl.1999.86.3.963  0.373
1999 Moseley PL, Wallen E, Hall DM, Kregel KC. IMPACT OF AGING ON HSP70 ACCUMULATION AND THERMOTOLERANCE WITH HEAT STRESS Medicine & Science in Sports & Exercise. 31: S374. DOI: 10.1097/00005768-199905001-01907  0.501
1998 Massett MP, Lewis SJ, Kregel KC. Effect of heating on the hemodynamic responses to vasoactive agents. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 275: R844-R853. PMID 29586998 DOI: 10.1152/Ajpregu.1998.275.3.R844  0.353
1998 Massett MP, Lewis SJ, Bates JN, Kregel KC. Effect of heating on vascular reactivity in rat mesenteric arteries. Journal of Applied Physiology (Bethesda, Md. : 1985). 85: 701-8. PMID 9688749 DOI: 10.1152/Jappl.1998.85.2.701  0.434
1998 Moseley PL, Kregel KC, Buettner GR, Clarkson PM. HEAT SHOCK PROTEINS, FREE RADICALS, AND OXIDATIVE STRESS: INTEGRATING BASIC SCIENCE WITH EXERCISE STRESS Medicine & Science in Sports & Exercise. 30: 225. DOI: 10.1097/00005768-199805001-01279  0.516
1998 Kregel KC, Weindruch RH, Moseley PM. IMPACT OF CALORIC RESTRICTION ON THERMOTOLERANCE AND HSP70 ACCUMULATION WITH HEAT STRESS Medicine & Science in Sports & Exercise. 30: 16. DOI: 10.1097/00005768-199805001-00087  0.549
1997 Kregel KC, Kenney MJ, Massett MP, Morgan DA, Lewis SJ. Role of nitrosyl factors in the hemodynamic adjustments to heat stress in the rat. The American Journal of Physiology. 273: H1537-43. PMID 9321847 DOI: 10.1152/Ajpheart.1997.273.3.H1537  0.424
1997 Woodman CR, Kregel KC, Tipton CM. Influence of simulated microgravity on the sympathetic response to exercise. The American Journal of Physiology. 272: R570-5. PMID 9124480 DOI: 10.1152/Ajpregu.1997.272.2.R570  0.3
1997 Stauss HM, Morgan DA, Anderson KE, Massett MP, Kregel KC. Modulation of baroreflex sensitivity and spectral power of blood pressure by heat stress and aging. The American Journal of Physiology. 272: H776-84. PMID 9124438 DOI: 10.1152/Ajpheart.1997.272.2.H776  0.433
1997 Kregel KC. Alterations in autonomic adjustments to acute hypoxia in conscious rats with aging. Journal of Applied Physiology (Bethesda, Md. : 1985). 80: 540-6. PMID 8929596 DOI: 10.1152/Jappl.1996.80.2.540  0.409
1996 Kregel KC, Moseley PL. Differential effects of exercise and heat stress on liver HSP70 accumulation with aging Journal of Applied Physiology. 80: 547-551. PMID 8929597 DOI: 10.1152/Jappl.1996.80.2.547  0.521
1996 Massett MP, Johnson DG, Kregel KC. Cardiovascular and sympathoadrenal responses to heat stress following water deprivation in rats. The American Journal of Physiology. 270: R652-9. PMID 8780233 DOI: 10.1152/Ajpregu.1996.270.3.R652  0.44
1996 Stauss HM, Morgan DA, Anderson KE, Massett MP, Kregel KC. Aging is not accompanied by sympathetic hyperresponsiveness to air-jet stress. The American Journal of Physiology. 271: H768-75. PMID 8770121 DOI: 10.1152/Ajpheart.1996.271.2.H768  0.341
1995 Kregel KC, Moseley PL, Skidmore R, Gutierrez JA, Guerriero V. HSP70 accumulation in tissues of heat-stressed rats is blunted with advancing age. Journal of Applied Physiology (Bethesda, Md. : 1985). 79: 1673-8. PMID 8594028 DOI: 10.1152/Jappl.1995.79.5.1673  0.625
1995 Skidmore R, Gutierrez JA, Guerriero V, Kregel KC. HSP70 induction during exercise and heat stress in rats: role of internal temperature. The American Journal of Physiology. 268: R92-7. PMID 7840344 DOI: 10.1152/Ajpregu.1995.268.1.R92  0.491
1995 Kregel KC, Meuterthies P, Wallen ES, Moseley PL. HSP70 ACCUMULATION IN SOLEUS MUSCLE DURING EXERCISE AND HEAT STRESS: INFLUENCE OF AGING. Medicine & Science in Sports & Exercise. 27: S125. DOI: 10.1249/00005768-199505001-00715  0.388
1995 Moseley PL, Meuterthies P, Wallen ES, Kregel KC. DIFFERENTIATED EFFECTS OF EXERCISE AND HEAT STRESS ON LIVER HSP70 ACCUMULATION WITH AGING. Medicine & Science in Sports & Exercise. 27: S125. DOI: 10.1249/00005768-199505001-00713  0.446
1994 Kregel KC, Stauss H, Unger T. Modulation of autonomic nervous system adjustments to heat stress by central ANG II receptor antagonism. The American Journal of Physiology. 266: R1985-91. PMID 8024055 DOI: 10.1152/Ajpregu.1994.266.6.R1985  0.478
1994 Kregel KC. Influence of aging on tissue-specific noradrenergic activity at rest and during nonexertional heating in rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 76: 1226-31. PMID 7911798 DOI: 10.1152/Jappl.1994.76.3.1226  0.5
1994 Kregel KC, Skidmore RL, Gutierrez JA, Guerriero V. 753 HSP70 INDUCTION DURING EXERCISE AND HEAT STRESS IN RATS Medicine & Science in Sports & Exercise. 26: S134. DOI: 10.1249/00005768-199405001-00755  0.525
1993 Kregel KC, Johnson DG, Seals DR. Tissue-specific noradrenergic activity during acute heat stress in rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 74: 1988-93. PMID 8514720 DOI: 10.1152/Jappl.1993.74.4.1988  0.448
1991 Kregel KC, Johnson DG, Tipton CM, Seals DR. Cardiovascular-sympathetic adjustments to nonexertional heat stress in mature and senescent Fischer 344 rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 69: 2043-9. PMID 2076998 DOI: 10.1152/Jappl.1990.69.6.2043  0.419
1991 Kregel KC, Overton JM, Johnson DG, Tipton CM, Seals DR. Mechanism for pressor response to nonexertional heating in the conscious rat. Journal of Applied Physiology (Bethesda, Md. : 1985). 71: 192-6. PMID 1917742 DOI: 10.1152/Jappl.1991.71.1.192  0.394
1990 Kregel KC, Tipton CM, Seals DR. Thermal adjustments to nonexertional heat stress in mature and senescent Fischer 344 rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 1337-42. PMID 2347776 DOI: 10.1152/Jappl.1990.68.4.1337  0.417
1990 Kregel KC, Gisolfi CV. Circulatory responses to vasoconstrictor agents during passive heating in the rat. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 1220-7. PMID 2341346 DOI: 10.1152/Jappl.1990.68.3.1220  0.423
1990 Kregel KC, Johnson DG, Tipton CM, Seals DR. Arterial baroreceptor reflex modulation of sympathetic-cardiovascular adjustments to heat stress. Hypertension (Dallas, Tex. : 1979). 15: 497-504. PMID 2332240 DOI: 10.1161/01.Hyp.15.5.497  0.432
1990 Kregel KC, Overton JM, Seals DR, Tipton CM, Fisher LA. Cardiovascular responses to exercise in the rat: role of corticotropin-releasing factor. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 561-7. PMID 2318769 DOI: 10.1152/Jappl.1990.68.2.561  0.323
1989 Kregel KC, Gisolfi CV. Circulatory responses to heat after celiac ganglionectomy or adrenal demedullation. Journal of Applied Physiology (Bethesda, Md. : 1985). 66: 1359-63. PMID 2708255 DOI: 10.1152/Jappl.1989.66.3.1359  0.426
1988 Kregel KC, Wall PT, Gisolfi CV. Peripheral vascular responses to hyperthermia in the rat. Journal of Applied Physiology (Bethesda, Md. : 1985). 64: 2582-8. PMID 3403442 DOI: 10.1152/Jappl.1988.64.6.2582  0.396
1985 Owen MD, Kregel KC, Wall PT, Gisolfi CV. EFFECTS OF CARBOHYDRATE INGESTION ON THERMOREGULATION, GASTRIC EMPTYING AND PLASMA VOLUME DURING EXERCISE IN THE HEAT Medicine & Science in Sports & Exercise. 17: 185. DOI: 10.1249/00005768-198504000-00021  0.302
1985 Kregel KC, Wall PT, Gisolfi CV. THERMAL RESPONSES AND NEUROANATOMICAL CHANGES PRODUCED BY SEVERE EXERCISE-HEAT STRESS IN THE RAT Medicine & Science in Sports & Exercise. 17: 185. DOI: 10.1249/00005768-198504000-00020  0.503
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