Hsin-Hsiung Tai - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Molecular Biology, Pharmacology

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Li X, Tai HH. Thromboxane A2 receptor-mediated release of matrix metalloproteinase-1 (MMP-1) induces expression of monocyte chemoattractant protein-1 (MCP-1) by activation of protease-activated receptor 2 (PAR2) in A549 human lung adenocarcinoma cells. Molecular Carcinogenesis. 53: 659-66. PMID 23475608 DOI: 10.1002/Mc.22020  0.309
2013 Li X, Tai HH. Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein -1 (MCP-1)/chemokine (C-C motif) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells. Plos One. 8: e54073. PMID 23349788 DOI: 10.1371/Journal.Pone.0054073  0.362
2012 Li X, Tai HH. Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells. Current Cancer Drug Targets. 12: 703-15. PMID 22515524 DOI: 10.2174/156800912801784884  0.305
2011 Tai HH. Prostaglandin catabolic enzymes as tumor suppressors. Cancer Metastasis Reviews. 30: 409-17. PMID 22020925 DOI: 10.1007/S10555-011-9314-Z  0.331
2011 Tai HH, Chi X, Tong M. Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). Prostaglandins & Other Lipid Mediators. 96: 37-40. PMID 21763448 DOI: 10.1016/J.Prostaglandins.2011.06.005  0.376
2011 Wu Y, Karna S, Choi CH, Tong M, Tai HH, Na DH, Jang CH, Cho H. Synthesis and biological evaluation of novel thiazolidinedione analogues as 15-hydroxyprostaglandin dehydrogenase inhibitors. Journal of Medicinal Chemistry. 54: 5260-4. PMID 21650226 DOI: 10.1021/Jm200390U  0.303
2010 Hamza A, Tong M, AbdulHameed MD, Liu J, Goren AC, Tai HH, Zhan CG. Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis. The Journal of Physical Chemistry. B. 114: 5605-16. PMID 20369883 DOI: 10.1021/Jp100668Y  0.314
2010 Wu Y, Tai HH, Cho H. Synthesis and SAR of thiazolidinedione derivatives as 15-PGDH inhibitors. Bioorganic & Medicinal Chemistry. 18: 1428-33. PMID 20122835 DOI: 10.1016/J.Bmc.2010.01.016  0.311
2010 Wei J, Yan W, Li X, Ding Y, Tai HH. Thromboxane receptor alpha mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells. Lung Cancer (Amsterdam, Netherlands). 69: 26-32. PMID 19853959 DOI: 10.1016/J.Lungcan.2009.09.009  0.559
2010 Zhao Y, Weng CC, Tong M, Wei J, Tai HH. Restoration of leukotriene B(4)-12-hydroxydehydrogenase/15- oxo-prostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo. Lung Cancer (Amsterdam, Netherlands). 68: 161-9. PMID 19595472 DOI: 10.1016/J.Lungcan.2009.06.011  0.334
2009 Li X, Tai HH. Activation of thromboxane A(2) receptors induces orphan nuclear receptor Nurr1 expression and stimulates cell proliferation in human lung cancer cells. Carcinogenesis. 30: 1606-13. PMID 19570744 DOI: 10.1093/Carcin/Bgp161  0.405
2009 Chi X, Freeman BM, Tong M, Zhao Y, Tai HH. 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells. Archives of Biochemistry and Biophysics. 487: 139-45. PMID 19501039 DOI: 10.1016/J.Abb.2009.05.017  0.368
2009 Yang W, Pan Y, Zheng F, Cho H, Tai HH, Zhan CG. Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase. Biophysical Journal. 96: 1931-8. PMID 19254552 DOI: 10.1016/J.Bpj.2008.11.051  0.31
2007 Li X, Wei J, Tai HH. Activation of extracellular signal-regulated kinase by 12-hydroxyheptadecatrienoic acid in prostate cancer PC3 cells. Archives of Biochemistry and Biophysics. 467: 20-30. PMID 17880908 DOI: 10.1016/J.Abb.2007.08.005  0.391
2007 Wei J, Yan W, Li X, Chang WC, Tai HH. Activation of thromboxane receptor alpha induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells. Biochemical Pharmacology. 74: 787-800. PMID 17632087 DOI: 10.1016/J.Bcp.2007.06.008  0.527
2007 Tai HH, Tong M, Ding Y. 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer. Prostaglandins & Other Lipid Mediators. 83: 203-8. PMID 17481556 DOI: 10.1016/J.Prostaglandins.2007.01.007  0.361
2006 Tong M, Ding Y, Tai HH. Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. Biochemical Pharmacology. 72: 701-9. PMID 16844092 DOI: 10.1016/J.Bcp.2006.06.004  0.322
2006 Cho H, Huang L, Hamza A, Gao D, Zhan CG, Tai HH. Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2. Bioorganic & Medicinal Chemistry. 14: 6486-91. PMID 16828555 DOI: 10.1016/J.Bmc.2006.06.030  0.339
2006 Tong M, Ding Y, Tai HH. Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells. Carcinogenesis. 27: 2170-9. PMID 16632868 DOI: 10.1093/Carcin/Bgl053  0.321
2006 Huang X, Yan W, Gao D, Tong M, Tai HH, Zhan CG. Structural and functional characterization of human microsomal prostaglandin E synthase-1 by computational modeling and site-directed mutagenesis. Bioorganic & Medicinal Chemistry. 14: 3553-62. PMID 16439136 DOI: 10.1016/J.Bmc.2006.01.010  0.553
2006 Yan W, Ding Y, Tai HH. 14-3-3zeta interacts with human thromboxane receptors and is involved in the agonist-induced activation of the extracellular-signal-regulated kinase. Biochemical Pharmacology. 71: 624-33. PMID 16413928 DOI: 10.1016/J.Bcp.2005.11.027  0.569
2006 Yan W, Tai HH. Glycogen synthase kinase-3 phosphorylation, T-cell factor signaling activation, and cell morphology change following stimulation of thromboxane receptor alpha. The Journal of Pharmacology and Experimental Therapeutics. 317: 267-74. PMID 16352701 DOI: 10.1124/jpet.105.096826  0.518
2005 Hamza A, Cho H, Tai HH, Zhan CG. Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation. Bioorganic & Medicinal Chemistry. 13: 4544-51. PMID 15908215 DOI: 10.1016/J.Bmc.2005.04.053  0.322
2005 Tong M, Tai HH. 15-Hydroxyprostaglandin dehydrogenase can be induced by dexamethasone and other glucocorticoids at the therapeutic level in A549 human lung adenocarcinoma cells. Archives of Biochemistry and Biophysics. 435: 50-5. PMID 15680906 DOI: 10.1016/J.Abb.2004.11.031  0.37
2005 Cho H, Hamza A, Zhan CG, Tai HH. Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase. Archives of Biochemistry and Biophysics. 433: 447-53. PMID 15581601 DOI: 10.1016/J.Abb.2004.09.036  0.339
2005 Backlund MG, Mann JR, Holla VR, Buchanan FG, Tai HH, Musiek ES, Milne GL, Katkuri S, DuBois RN. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. The Journal of Biological Chemistry. 280: 3217-23. PMID 15542609 DOI: 10.1074/Jbc.M411221200  0.35
2005 Ding Y, Tong M, Liu S, Moscow JA, Tai HH. NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. Carcinogenesis. 26: 65-72. PMID 15358636 DOI: 10.1093/Carcin/Bgh277  0.363
2003 Cho H, Oliveira MA, Tai HH. Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. Archives of Biochemistry and Biophysics. 419: 139-46. PMID 14592457 DOI: 10.1016/J.Abb.2003.09.019  0.326
2003 Gao L, Zackert WE, Hasford JJ, Danekis ME, Milne GL, Remmert C, Reese J, Yin H, Tai HH, Dey SK, Porter NA, Morrow JD. Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase. The Journal of Biological Chemistry. 278: 28479-89. PMID 12746435 DOI: 10.1074/Jbc.M303984200  0.306
2002 Tai HH, Ensor CM, Zhou H, Yan F. Structure and function of human NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase. Advances in Experimental Medicine and Biology. 507: 245-50. PMID 12664592 DOI: 10.1007/978-1-4615-0193-0_37  0.386
2002 Tai HH, Ensor CM, Tong M, Zhou H, Yan F. Prostaglandin catabolizing enzymes. Prostaglandins & Other Lipid Mediators. 68: 483-93. PMID 12432938 DOI: 10.1016/S0090-6980(02)00050-3  0.377
2002 Cho H, Tai HH. Thiazolidinediones as a novel class of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors. Archives of Biochemistry and Biophysics. 405: 247-51. PMID 12220539 DOI: 10.1016/S0003-9861(02)00352-1  0.373
2002 Yamamoto S, Yan F, Zhou H, Tai HH. Agents that elevate cyclic AMP induce receptor phosphorylation primarily at serine 331 in HEK 293 cells overexpressing human thromboxane receptor alpha. Biochemical Pharmacology. 64: 375-83. PMID 12147288 DOI: 10.1016/S0006-2952(02)01053-5  0.367
2001 Yamamoto S, Yan F, Zhou H, Tai H. Serine 331 Is the Major Site of Receptor Phosphorylation Induced by Agents That Activate Protein Kinase G in HEK 293 Cells Overexpressing Thromboxane Receptor α Archives of Biochemistry and Biophysics. 393: 97-105. PMID 11516166 DOI: 10.1006/Abbi.2001.2505  0.365
2001 Kozak KR, Crews BC, Ray JL, Tai HH, Morrow JD, Marnett LJ. Metabolism of prostaglandin glycerol esters and prostaglandin ethanolamides in vitro and in vivo. The Journal of Biological Chemistry. 276: 36993-8. PMID 11447235 DOI: 10.1074/Jbc.M105854200  0.324
2001 Zhou H, Yan F, Tai H. C‐Terminal region of human NAD+‐dependent 15‐hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates Febs Journal. 268: 3368-3374. PMID 11422365 DOI: 10.1046/J.1432-1327.2001.02218.X  0.378
2000 Tong M, Tai HH. Induction of NAD+-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells Biochemical and Biophysical Research Communications. 276: 77-81. PMID 11006085 DOI: 10.1006/Bbrc.2000.3437  0.393
2000 Tong M, Tai HH. Dexamethasone inhibits the induction of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells Biochimica Et Biophysica Acta - Molecular Cell Research. 1497: 61-68. PMID 10838159 DOI: 10.1016/S0167-4889(00)00039-2  0.43
2000 Clish CB, Levy BD, Chiang N, Tai HH, Serhan CN. Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation. The Journal of Biological Chemistry. 275: 25372-80. PMID 10837478 DOI: 10.1074/Jbc.M002863200  0.391
2000 Zhou H, Tai H. Expression and Functional Characterization of Mutant Human CXCR4 in Insect Cells: Role of Cysteinyl and Negatively Charged Residues in Ligand Binding Archives of Biochemistry and Biophysics. 373: 211-217. PMID 10620340 DOI: 10.1006/Abbi.1999.1555  0.34
1999 Zhou H, Yan F, Yamamoto S, Tai H. Phenylalanine 138 in the second intracellular loop of human thromboxane receptor is critical for receptor-G-protein coupling. Biochemical and Biophysical Research Communications. 264: 171-175. PMID 10527859 DOI: 10.1006/Bbrc.1999.1508  0.318
1999 Zhou H, Tai H. Characterization of recombinant human CXCR4 in insect cells: role of extracellular domains and N-glycosylation in ligand binding. Archives of Biochemistry and Biophysics. 369: 267-276. PMID 10486146 DOI: 10.1006/Abbi.1999.1368  0.319
1999 Zhou H, Tai H. Threonine 188 is critical for interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. Biochemical and Biophysical Research Communications. 257: 414-417. PMID 10198228 DOI: 10.1006/Bbrc.1999.0356  0.392
1998 Chiang N, Takano T, Clish CB, Petasis NA, Tai HH, Serhan CN. Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA. The Journal of Pharmacology and Experimental Therapeutics. 287: 779-90. PMID 9808710 DOI: 10.1016/S0090-6980(99)90421-5  0.381
1998 Ensor CM, Zhang H, Tai H. Purification, cDNA cloning and expression of 15-oxoprostaglandin 13-reductase from pig lung. Biochemical Journal. 330: 103-108. PMID 9461497 DOI: 10.1042/Bj3300103  0.362
1997 Tai H, Huang C, Chiang N. Structure and Function of Prostanoid Receptors as Revealed by Site-Directed Mutagenesis Advances in Experimental Medicine and Biology. 407: 205-209. PMID 9321954 DOI: 10.1007/978-1-4899-1813-0_31  0.308
1997 Ensor CM, Tai H. Photoaffinity labeling of NAD(+)-linked enzymes. Methods in Enzymology. 280: 204-210. PMID 9211315 DOI: 10.1016/S0076-6879(97)80111-5  0.333
1997 Zhang H, Matsuo M, Zhou H, Ensor CM, Tai HH. Cloning and expression of the cDNA for rat NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. Gene. 188: 41-4. PMID 9099857 DOI: 10.1016/S0378-1119(96)00774-3  0.339
1996 Matsuo M, Ensor CM, Tai H. Cloning and expression of the cDNA for mouse NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. Biochimica Et Biophysica Acta. 1309: 21-24. PMID 8950170 DOI: 10.1016/S0167-4781(96)00123-6  0.37
1996 Ensor CM, Tai H. Site-directed mutagenesis of the conserved serine 138 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase to an alanine results in an inactive enzyme. Biochemical and Biophysical Research Communications. 220: 330-333. PMID 8645305 DOI: 10.1006/Bbrc.1996.0405  0.4
1996 Huang C, Tai HH. Ser-268 plays an important role in ligand binding of prostaglandin E2 receptor EP3alpha subtype. Archives of Biochemistry and Biophysics. 327: 161-6. PMID 8615686 DOI: 10.1006/Abbi.1996.0104  0.353
1995 Ensor CM, Tai H. 15-Hydroxyprostaglandin dehydrogenase Journal of Lipid Mediators and Cell Signalling. 12: 313-319. PMID 8777575 DOI: 10.1016/0929-7855(95)00040-W  0.307
1995 Huang C, Tai H. Expression and site-directed mutagenesis of mouse prostaglandin E2 receptor EP3 subtype in insect cells. Biochemical Journal. 307: 493-498. PMID 7733888 DOI: 10.1042/Bj3070493  0.334
1994 Shen R, Zhang L, Baek SJ, Tai H, Lee K. The porcine thromboxane synthase-encoding cDNA: sequence, mRNA expression and enzyme production m Sf9 insect cells Gene. 140: 261-265. PMID 8144035 DOI: 10.1016/0378-1119(94)90555-X  0.374
1994 Ensor CM, Tai H. Bacterial expression and site-directed mutagenesis of two critical residues (tyrosine-151 and lysine-155) of human placental NAD+ -dependent 15-hydroxyprostaglandin dehydrogenase Biochimica Et Biophysica Acta. 1208: 151-156. PMID 8086429 DOI: 10.1016/0167-4838(94)90172-4  0.418
1993 Xia Z, Shen R, Baek SJ, Tai H. Expression of two different forms of cDNA for thromboxane synthase in insect cells and site-directed mutagenesis of a critical cysteine residue. Biochemical Journal. 295: 457-461. PMID 8240243 DOI: 10.1042/Bj2950457  0.413
1991 Xun C, Ensor CM, Tai H. Regulation of synthesis and activity of NAD+-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human erythroleukemia (HEL) cells Biochemical and Biophysical Research Communications. 177: 1258-1265. PMID 2059213 DOI: 10.1016/0006-291X(91)90677-Y  0.409
1991 Ensor CM, Tai H. Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme Biochemical and Biophysical Research Communications. 176: 840-845. PMID 2025296 DOI: 10.1016/S0006-291X(05)80262-1  0.409
1991 Xun C, Tian Z, Tai H. Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester. Biochemical Journal. 279: 553-558. PMID 1953649 DOI: 10.1042/Bj2790553  0.415
1990 Mak OT, Liu Y, Tai H. Purification and characterization of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney. Biochimica Et Biophysica Acta. 1035: 190-196. PMID 2393668 DOI: 10.1016/0304-4165(90)90115-D  0.376
1990 Wu P, Fritzo M, Tai H. Purification and characterization of an NAD(+)-dependent dehydrogenase that catalyzes the oxidation of thromboxane B2 at C-11 from porcine liver. Development and application of 11-dehydro-thromboxane B2 radioimmunoassay to enzyme assay. Biochimica Et Biophysica Acta. 1036: 55-63. PMID 2223826 DOI: 10.1016/0304-4165(90)90213-G  0.34
1990 Tai CL, Mak OT, Arai T, Tai H. Monoclonal antibodies that inhibit the enzyme activity of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. Biochemical Journal. 267: 75-78. PMID 1691637 DOI: 10.1042/Bj2670075  0.35
1988 Chau L, Tai H. Monoglyceride and diglyceride lipases from human platelet microsomes. Biochimica Et Biophysica Acta. 963: 436-444. PMID 3143416 DOI: 10.1016/0005-2760(88)90312-8  0.375
1988 Fuse I, Tai H. Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets? Biochimica Et Biophysica Acta. 972: 54-59. PMID 3140902 DOI: 10.1016/0167-4889(88)90102-4  0.312
1985 Fukuda S, Hamasaki Y, Tai H. Increase in enzyme activities of prostaglandin biosynthesis and catabolism by acute ureteral ligation in rat kidney. Life Sciences. 37: 1249-1255. PMID 3930905 DOI: 10.1016/0024-3205(85)90137-7  0.322
1985 Hamasaki Y, Tai H. Gossypol, a potent inhibitor of arachidonate 5- and 12-lipoxygenases. Biochimica Et Biophysica Acta. 834: 37-41. PMID 3919771 DOI: 10.1016/0005-2760(85)90173-0  0.311
1984 Tai CL, Tai H. A radioimmunoassay for prostaglandin endoperoxide synthetase. Prostaglandins, Leukotrienes and Medicine. 14: 243-254. PMID 6204341 DOI: 10.1016/0262-1746(84)90208-7  0.35
1982 Tai HH, Sih CJ. Assay of prostacyclin synthase using [5,6-3H]PGH2. Methods in Enzymology. 86: 99-105. PMID 6813652 DOI: 10.1016/0076-6879(82)86175-2  0.325
1977 Tai HH, Yuan B. A simple and sensitive assay for 9-hydroxyprostaglandin dehydrogenase Analytical Biochemistry. 78: 410-422. PMID 851214 DOI: 10.1016/0003-2697(77)90102-6  0.38
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